Organism Overview: Sulcia muelleri CARI


 
lipB protein networkhttps://string-db.org/network/706194.SMCARI_001lipoyl-(acyl-carrier-protein)-protein-N- lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- de [...]
yidC protein networkhttps://string-db.org/network/706194.SMCARI_002Inner membrane protein YidC.
hisS protein networkhttps://string-db.org/network/706194.SMCARI_003histidyl-tRNA synthetase.
valS protein networkhttps://string-db.org/network/706194.SMCARI_004valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
dnaN protein networkhttps://string-db.org/network/706194.SMCARI_005DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadi [...]
pheT protein networkhttps://string-db.org/network/706194.SMCARI_006phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
aroB protein networkhttps://string-db.org/network/706194.SMCARI_0073-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
gyrA protein networkhttps://string-db.org/network/706194.SMCARI_008DNA gyrase A subunit.
rpsA protein networkhttps://string-db.org/network/706194.SMCARI_009Putative 30S ribosomal protein S1.
ADM89846.1 protein networkhttps://string-db.org/network/706194.SMCARI_010Putative type II NADH dehydrogenase.
rho protein networkhttps://string-db.org/network/706194.SMCARI_011Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
prfA protein networkhttps://string-db.org/network/706194.SMCARI_012Peptide chain release factor 1.
aspS protein networkhttps://string-db.org/network/706194.SMCARI_013aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
aroD protein networkhttps://string-db.org/network/706194.SMCARI_0143-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
fabF protein networkhttps://string-db.org/network/706194.SMCARI_0153-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
acpP protein networkhttps://string-db.org/network/706194.SMCARI_016Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
atpC protein networkhttps://string-db.org/network/706194.SMCARI_017Putative ATP synthase F1, epsilon subunit.
atpD protein networkhttps://string-db.org/network/706194.SMCARI_018F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPas [...]
ksgA protein networkhttps://string-db.org/network/706194.SMCARI_019Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
ileS protein networkhttps://string-db.org/network/706194.SMCARI_021isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
lspA protein networkhttps://string-db.org/network/706194.SMCARI_022Putative signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
lepA protein networkhttps://string-db.org/network/706194.SMCARI_024GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
holB protein networkhttps://string-db.org/network/706194.SMCARI_025Putative DNA polymerase III delta' subunit.
ADM89860.1 protein networkhttps://string-db.org/network/706194.SMCARI_026Putative U32 family peptidase; Strong similarity to PFAM PF01136.
ADM89861.1 protein networkhttps://string-db.org/network/706194.SMCARI_027Conserved hypothetical protein.
glnS protein networkhttps://string-db.org/network/706194.SMCARI_028glutaminyl-tRNA synthetase.
mnmG protein networkhttps://string-db.org/network/706194.SMCARI_029tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG/GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of cert [...]
ybeY protein networkhttps://string-db.org/network/706194.SMCARI_030Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
rsmI protein networkhttps://string-db.org/network/706194.SMCARI_031Methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
prsA protein networkhttps://string-db.org/network/706194.SMCARI_033Ribose-phosphate pyrophosphokinase.
rplY protein networkhttps://string-db.org/network/706194.SMCARI_03450S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
metG protein networkhttps://string-db.org/network/706194.SMCARI_035methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
lgt protein networkhttps://string-db.org/network/706194.SMCARI_036Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
gltX protein networkhttps://string-db.org/network/706194.SMCARI_037glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
atpG protein networkhttps://string-db.org/network/706194.SMCARI_038ATP synthase F1, gamma subunit.
atpA protein networkhttps://string-db.org/network/706194.SMCARI_039ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains fa [...]
atpH protein networkhttps://string-db.org/network/706194.SMCARI_040ATP synthase F1, delta subunit.
atpF protein networkhttps://string-db.org/network/706194.SMCARI_041ATP synthase F0 B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
atpE protein networkhttps://string-db.org/network/706194.SMCARI_042ATP synthase F0 subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extram [...]
atpB protein networkhttps://string-db.org/network/706194.SMCARI_043ATP synthase F0 subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
dnaG protein networkhttps://string-db.org/network/706194.SMCARI_044DNA primase.
lysC protein networkhttps://string-db.org/network/706194.SMCARI_045Putative aspartate kinase; Belongs to the aspartokinase family.
ADM89879.1 protein networkhttps://string-db.org/network/706194.SMCARI_046MarC family integral membrane protein.
ADM89880.1 protein networkhttps://string-db.org/network/706194.SMCARI_047Putative trmH/spoU family tRNA/rRNA methyltransferase.
leuB protein networkhttps://string-db.org/network/706194.SMCARI_0483-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
leuD protein networkhttps://string-db.org/network/706194.SMCARI_0493-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. Leu [...]
leuC protein networkhttps://string-db.org/network/706194.SMCARI_0503-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
leuA protein networkhttps://string-db.org/network/706194.SMCARI_0512-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
ADM89885.1 protein networkhttps://string-db.org/network/706194.SMCARI_052Conserved hypothetical protein.
tyrS protein networkhttps://string-db.org/network/706194.SMCARI_053tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
era protein networkhttps://string-db.org/network/706194.SMCARI_054GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly als [...]
leuS protein networkhttps://string-db.org/network/706194.SMCARI_055leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
ADM89889.1 protein networkhttps://string-db.org/network/706194.SMCARI_058Putative ribosomal large subunit pseudouridine synthase; Based on similarity to Pfams PF01479 and PF00849; RsuA-like protein; Belongs to the pseudouridine synthase RsuA family.
korB protein networkhttps://string-db.org/network/706194.SMCARI_0592-oxoglutarate ferredoxin oxidoreductase beta subunit.
ADM89891.1 protein networkhttps://string-db.org/network/706194.SMCARI_060Hypothetical protein.
serS protein networkhttps://string-db.org/network/706194.SMCARI_061seryl-tRNA synthetase.
rpmB protein networkhttps://string-db.org/network/706194.SMCARI_06250S ribosomal subunit protein L28; Belongs to the bacterial ribosomal protein bL28 family.
rpmG protein networkhttps://string-db.org/network/706194.SMCARI_06350S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
ADM89895.1 protein networkhttps://string-db.org/network/706194.SMCARI_064Hypothetical protein.
truA protein networkhttps://string-db.org/network/706194.SMCARI_067tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
rpoC protein networkhttps://string-db.org/network/706194.SMCARI_068DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/706194.SMCARI_069DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/706194.SMCARI_07050S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the ba [...]
rplJ protein networkhttps://string-db.org/network/706194.SMCARI_07150S ribosomal protein L10.
rplA protein networkhttps://string-db.org/network/706194.SMCARI_07250S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/706194.SMCARI_07350S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
tuf protein networkhttps://string-db.org/network/706194.SMCARI_076Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
ADM89904.1 protein networkhttps://string-db.org/network/706194.SMCARI_081Cytochrome c.
ADM89905.1 protein networkhttps://string-db.org/network/706194.SMCARI_082Molybdopterin oxidoreductase, iron-sulfur binding subunit.
ADM89906.1 protein networkhttps://string-db.org/network/706194.SMCARI_083Molybdopterin oxidoredutase membrane subunit.
ADM89907.1 protein networkhttps://string-db.org/network/706194.SMCARI_084Conserved hypothetical protein.
ADM89908.1 protein networkhttps://string-db.org/network/706194.SMCARI_085Conserved hypothetical protein.
ADM89909.1 protein networkhttps://string-db.org/network/706194.SMCARI_086Conserved hypothetical protein.
sufE protein networkhttps://string-db.org/network/706194.SMCARI_087Cysteine desulfurase SufE subunit.
ispB protein networkhttps://string-db.org/network/706194.SMCARI_088Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
sucC protein networkhttps://string-db.org/network/706194.SMCARI_094succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus repr [...]
dnaX protein networkhttps://string-db.org/network/706194.SMCARI_095DNA polymerase III subunit gamma; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exon [...]
tatA protein networkhttps://string-db.org/network/706194.SMCARI_096Putative Sec-independent protein translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their [...]
clpP protein networkhttps://string-db.org/network/706194.SMCARI_097ATP-dependent Clp protease, proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrad [...]
clpX protein networkhttps://string-db.org/network/706194.SMCARI_098ATP-dependent protease ATP-binding subunit; Belongs to the ClpX chaperone family.
mutS protein networkhttps://string-db.org/network/706194.SMCARI_099DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA.
tsf protein networkhttps://string-db.org/network/706194.SMCARI_102Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
rpsB protein networkhttps://string-db.org/network/706194.SMCARI_10330S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
rpsI protein networkhttps://string-db.org/network/706194.SMCARI_10430S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
rplM protein networkhttps://string-db.org/network/706194.SMCARI_10550S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
dnaK protein networkhttps://string-db.org/network/706194.SMCARI_106Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
upp protein networkhttps://string-db.org/network/706194.SMCARI_107Uracil phosphoribosyltransferase; Belongs to the class-II aminoacyl-tRNA synthetase family.
infC protein networkhttps://string-db.org/network/706194.SMCARI_108Translation initiation factor 3; Belongs to the IF-3 family.
rpmI protein networkhttps://string-db.org/network/706194.SMCARI_10950S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
rplT protein networkhttps://string-db.org/network/706194.SMCARI_11050S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
def protein networkhttps://string-db.org/network/706194.SMCARI_111Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
ADM89928.1 protein networkhttps://string-db.org/network/706194.SMCARI_112Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
dapD protein networkhttps://string-db.org/network/706194.SMCARI_1132,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
ilvE protein networkhttps://string-db.org/network/706194.SMCARI_114Branched-chain amino acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
ADM89931.1 protein networkhttps://string-db.org/network/706194.SMCARI_115tRNA nucleotidyltransferase.
trmU protein networkhttps://string-db.org/network/706194.SMCARI_116tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
dnaJ protein networkhttps://string-db.org/network/706194.SMCARI_117Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an [...]
grpE protein networkhttps://string-db.org/network/706194.SMCARI_118Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is [...]
rny protein networkhttps://string-db.org/network/706194.SMCARI_119Conserved hypothetical protein; Endoribonuclease that initiates mRNA decay.
lpdA protein networkhttps://string-db.org/network/706194.SMCARI_120Dihydrolipoamide dehydrogenase.
dnaB protein networkhttps://string-db.org/network/706194.SMCARI_121Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
ADM89938.1 protein networkhttps://string-db.org/network/706194.SMCARI_122M42 family metalloprotease.
pta protein networkhttps://string-db.org/network/706194.SMCARI_123Phosphate acetyltransferase.
ackA protein networkhttps://string-db.org/network/706194.SMCARI_124Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
trmE protein networkhttps://string-db.org/network/706194.SMCARI_125tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
uvrD protein networkhttps://string-db.org/network/706194.SMCARI_126Putative DNA helicase II; Based on similarity to TIGRfam TIGR10175, Pfam PF00580.
dnaE protein networkhttps://string-db.org/network/706194.SMCARI_128DNA polymerase III, alpha subunit.
ADM89944.1 protein networkhttps://string-db.org/network/706194.SMCARI_129Putative argininosuccinate synthase/acetyltransferase activity of N-acetylglutamate synthase; ArgG/ArgA.
argC protein networkhttps://string-db.org/network/706194.SMCARI_130N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydroge [...]
argD protein networkhttps://string-db.org/network/706194.SMCARI_131Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
carA protein networkhttps://string-db.org/network/706194.SMCARI_132Carbamoyl phosphate synthase small subunit; Belongs to the CarA family.
carB protein networkhttps://string-db.org/network/706194.SMCARI_133Carbamyl phosphate synthase large subunit.
argF protein networkhttps://string-db.org/network/706194.SMCARI_134Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
argB protein networkhttps://string-db.org/network/706194.SMCARI_135Acetylglutamate kinase.
argE protein networkhttps://string-db.org/network/706194.SMCARI_136Acetylornithine deacetylase.
aroK protein networkhttps://string-db.org/network/706194.SMCARI_139Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
tilS protein networkhttps://string-db.org/network/706194.SMCARI_140Putative tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cy [...]
tal protein networkhttps://string-db.org/network/706194.SMCARI_141Putative translaldolase.
proS protein networkhttps://string-db.org/network/706194.SMCARI_142prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
lon protein networkhttps://string-db.org/network/706194.SMCARI_143ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cel [...]
lysA protein networkhttps://string-db.org/network/706194.SMCARI_144Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
aroC protein networkhttps://string-db.org/network/706194.SMCARI_146Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
htpG protein networkhttps://string-db.org/network/706194.SMCARI_147Heat shock protein 90.
ADM89960.1 protein networkhttps://string-db.org/network/706194.SMCARI_148Putative MiaB-like protein.
secA protein networkhttps://string-db.org/network/706194.SMCARI_149Translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins [...]
rplS protein networkhttps://string-db.org/network/706194.SMCARI_15050S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
ADM89963.1 protein networkhttps://string-db.org/network/706194.SMCARI_1513Fe-4S ferredoxin:4Fe-4S ferredoxin, iron-sulfur binding domain protein.
glyS protein networkhttps://string-db.org/network/706194.SMCARI_152glycyl-tRNA synthetase.
menA protein networkhttps://string-db.org/network/706194.SMCARI_1531,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
thrC protein networkhttps://string-db.org/network/706194.SMCARI_154Threonine synthase.
thrB protein networkhttps://string-db.org/network/706194.SMCARI_155Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
thrA protein networkhttps://string-db.org/network/706194.SMCARI_156Aspartokinase/homoserine dehydrogenase.
maeA protein networkhttps://string-db.org/network/706194.SMCARI_161Putative NAD(P)-dependent malic enzyme.
ccoP protein networkhttps://string-db.org/network/706194.SMCARI_163Putative cytochrome c oxidase, cbb3-type, ccoP subunit.
ADM89971.1 protein networkhttps://string-db.org/network/706194.SMCARI_164Bifunctional cbb3-type cytochrome c oxidase, ccoN subunit/ccoO subunit; Belongs to the heme-copper respiratory oxidase family.
ADM89972.1 protein networkhttps://string-db.org/network/706194.SMCARI_165Cation transport ATPase, E1-E2 family protein.
engA protein networkhttps://string-db.org/network/706194.SMCARI_166GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) G [...]
lipA protein networkhttps://string-db.org/network/706194.SMCARI_167Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, there [...]
rpmH protein networkhttps://string-db.org/network/706194.SMCARI_16850S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
efp protein networkhttps://string-db.org/network/706194.SMCARI_169Putative elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions [...]
sucD protein networkhttps://string-db.org/network/706194.SMCARI_170succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus re [...]
ADM89978.1 protein networkhttps://string-db.org/network/706194.SMCARI_171CAAX amino terminal protease family protein.
korA protein networkhttps://string-db.org/network/706194.SMCARI_1732-oxoglutarate ferredoxin oxidoreductase alpha subunit.
ADM89980.1 protein networkhttps://string-db.org/network/706194.SMCARI_174Mrp/Nbp35 family ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
trpS protein networkhttps://string-db.org/network/706194.SMCARI_175tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
ADM89982.1 protein networkhttps://string-db.org/network/706194.SMCARI_177Putative outer membrane protein.
rrf protein networkhttps://string-db.org/network/706194.SMCARI_178Ribosome recycling factor.
asnS protein networkhttps://string-db.org/network/706194.SMCARI_179asparaginyl-tRNA synthetase.
rplU protein networkhttps://string-db.org/network/706194.SMCARI_18250S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
rpmA protein networkhttps://string-db.org/network/706194.SMCARI_18350S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
rpsF protein networkhttps://string-db.org/network/706194.SMCARI_18530S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
rpsR protein networkhttps://string-db.org/network/706194.SMCARI_18630S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
rplI protein networkhttps://string-db.org/network/706194.SMCARI_18750S ribosomal protein L9.
ADM89990.1 protein networkhttps://string-db.org/network/706194.SMCARI_188Conserved hypothetical protein.
ADM89991.1 protein networkhttps://string-db.org/network/706194.SMCARI_189Conserved hypothetical protein.
dapA protein networkhttps://string-db.org/network/706194.SMCARI_190Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
prfB protein networkhttps://string-db.org/network/706194.SMCARI_192Peptide chain release factor RF2.
dapB protein networkhttps://string-db.org/network/706194.SMCARI_193Dihydrodipicolinate reductase; Belongs to the DapB family.
lepB protein networkhttps://string-db.org/network/706194.SMCARI_194Signal peptidase I; Belongs to the peptidase S26 family.
rpsU protein networkhttps://string-db.org/network/706194.SMCARI_19530S ribosomal subunit protein S21; Belongs to the bacterial ribosomal protein bS21 family.
aroE protein networkhttps://string-db.org/network/706194.SMCARI_196Putative shikimate 5-dehydrogenase.
obg protein networkhttps://string-db.org/network/706194.SMCARI_197GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role [...]
lpdA-2 protein networkhttps://string-db.org/network/706194.SMCARI_198Dihydrolipoamide dehydrogenase.
ADM90000.1 protein networkhttps://string-db.org/network/706194.SMCARI_200Conserved hypothetical protein.
alaS protein networkhttps://string-db.org/network/706194.SMCARI_202alanyl-tRNA synthetase.
sucA protein networkhttps://string-db.org/network/706194.SMCARI_2032-oxoglutarate dehydrogenase, E1 component.
sucB protein networkhttps://string-db.org/network/706194.SMCARI_2042-oxoglutarate dehydrogenase, E2 component.
tatC protein networkhttps://string-db.org/network/706194.SMCARI_205Putative Sec-independent protein translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their [...]
smpB protein networkhttps://string-db.org/network/706194.SMCARI_206SsrA (tmRNA)-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribos [...]
ADM90006.1 protein networkhttps://string-db.org/network/706194.SMCARI_207Putative Fe-S assembly protein; Based on similarity to TIGRfam TIGR02945.
ADM90007.1 protein networkhttps://string-db.org/network/706194.SMCARI_208Conserved hypothetical protein.
groEL protein networkhttps://string-db.org/network/706194.SMCARI_20960 kDa chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
groES protein networkhttps://string-db.org/network/706194.SMCARI_21010 kDa chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
sufB protein networkhttps://string-db.org/network/706194.SMCARI_211FeS assembly protein SufB.
sufC protein networkhttps://string-db.org/network/706194.SMCARI_212Putative FeS assembly ATPase SufC.
sufD protein networkhttps://string-db.org/network/706194.SMCARI_213Putative FeS assembly protein SufD.
sufS protein networkhttps://string-db.org/network/706194.SMCARI_214Cysteine desulfurase, SufS; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
infB protein networkhttps://string-db.org/network/706194.SMCARI_215Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
aroG protein networkhttps://string-db.org/network/706194.SMCARI_216Putative phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase.
pheA protein networkhttps://string-db.org/network/706194.SMCARI_217Putative prephenate dehydratase.
asd protein networkhttps://string-db.org/network/706194.SMCARI_218Aspartate semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family.
rpsT protein networkhttps://string-db.org/network/706194.SMCARI_21930S ribosomal protein S20.
aroA protein networkhttps://string-db.org/network/706194.SMCARI_2213-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
rpsP protein networkhttps://string-db.org/network/706194.SMCARI_22230S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
greB protein networkhttps://string-db.org/network/706194.SMCARI_224Putative transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property [...]
gyrB protein networkhttps://string-db.org/network/706194.SMCARI_225DNA gyrase B subunit.
gidB protein networkhttps://string-db.org/network/706194.SMCARI_226Glucose-inhibited division protein B; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
aspC protein networkhttps://string-db.org/network/706194.SMCARI_227Aspartate aminotransferase.
rpmF protein networkhttps://string-db.org/network/706194.SMCARI_22850S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
pdhB protein networkhttps://string-db.org/network/706194.SMCARI_229Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
fbaA protein networkhttps://string-db.org/network/706194.SMCARI_230Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphat [...]
rpoD protein networkhttps://string-db.org/network/706194.SMCARI_232RNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
pnp protein networkhttps://string-db.org/network/706194.SMCARI_233Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
rpsO protein networkhttps://string-db.org/network/706194.SMCARI_23430S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
ubiE protein networkhttps://string-db.org/network/706194.SMCARI_235Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
rpmE protein networkhttps://string-db.org/network/706194.SMCARI_23650S ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family.
rpsL protein networkhttps://string-db.org/network/706194.SMCARI_23730S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S an [...]
rpsG protein networkhttps://string-db.org/network/706194.SMCARI_23830S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
fusA protein networkhttps://string-db.org/network/706194.SMCARI_239Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) [...]
rpsJ protein networkhttps://string-db.org/network/706194.SMCARI_24030S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rplC protein networkhttps://string-db.org/network/706194.SMCARI_24150S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal rib [...]
rplD protein networkhttps://string-db.org/network/706194.SMCARI_24250S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel.
rplW protein networkhttps://string-db.org/network/706194.SMCARI_243Putative 50S ribosomal subunit protein L23; Based on a very weak similarity to Pfam PF00276 and ribosomal gene synteny.
rplB protein networkhttps://string-db.org/network/706194.SMCARI_24450S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rpsS protein networkhttps://string-db.org/network/706194.SMCARI_24530S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplV protein networkhttps://string-db.org/network/706194.SMCARI_24650S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wal [...]
rpsC protein networkhttps://string-db.org/network/706194.SMCARI_24730S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplP protein networkhttps://string-db.org/network/706194.SMCARI_24850S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsQ protein networkhttps://string-db.org/network/706194.SMCARI_24930S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rplN protein networkhttps://string-db.org/network/706194.SMCARI_25050S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rplX protein networkhttps://string-db.org/network/706194.SMCARI_25150S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplE protein networkhttps://string-db.org/network/706194.SMCARI_25250S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rpsN protein networkhttps://string-db.org/network/706194.SMCARI_25330S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the un [...]
rpsH protein networkhttps://string-db.org/network/706194.SMCARI_25430S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to [...]
rplF protein networkhttps://string-db.org/network/706194.SMCARI_25550S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rplR protein networkhttps://string-db.org/network/706194.SMCARI_25650S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
rpsE protein networkhttps://string-db.org/network/706194.SMCARI_25730S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 fam [...]
rplO protein networkhttps://string-db.org/network/706194.SMCARI_258Putative 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
secY protein networkhttps://string-db.org/network/706194.SMCARI_259Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at t [...]
infA protein networkhttps://string-db.org/network/706194.SMCARI_260Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
rpmJ protein networkhttps://string-db.org/network/706194.SMCARI_26150S ribosomal subunit protein L36; Belongs to the bacterial ribosomal protein bL36 family.
rpsM protein networkhttps://string-db.org/network/706194.SMCARI_26230S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpsK protein networkhttps://string-db.org/network/706194.SMCARI_26330S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsD protein networkhttps://string-db.org/network/706194.SMCARI_26430S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpoA protein networkhttps://string-db.org/network/706194.SMCARI_265DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplQ protein networkhttps://string-db.org/network/706194.SMCARI_26650S ribosomal protein L17.
dapF protein networkhttps://string-db.org/network/706194.SMCARI_267Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
mraW protein networkhttps://string-db.org/network/706194.SMCARI_268S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
putA protein networkhttps://string-db.org/network/706194.SMCARI_270Delta-1-pyrroline-5-carboxylate dehydrogenase.
mutL protein networkhttps://string-db.org/network/706194.SMCARI_271Putative DNA mismatch repair protein MutL; Belongs to the DNA mismatch repair MutL/HexB family.
argH protein networkhttps://string-db.org/network/706194.SMCARI_272Argininosuccinate lyase.
lysS protein networkhttps://string-db.org/network/706194.SMCARI_273lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
acoA protein networkhttps://string-db.org/network/706194.SMCARI_275Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
pdhC protein networkhttps://string-db.org/network/706194.SMCARI_276Dihydrolipoamide acyltransferase E2 component.
terC protein networkhttps://string-db.org/network/706194.SMCARI_277Integral membrane protein TerC family.
pfkA protein networkhttps://string-db.org/network/706194.SMCARI_2786-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
gapA protein networkhttps://string-db.org/network/706194.SMCARI_279Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
ADM90074.1 protein networkhttps://string-db.org/network/706194.SMCARI_280Conserved hypothetical protein.
ADM90075.1 protein networkhttps://string-db.org/network/706194.SMCARI_281Conserved hypothetical protein.
ADM90076.1 protein networkhttps://string-db.org/network/706194.SMCARI_282Putative trmH/spoU family tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
pheS protein networkhttps://string-db.org/network/706194.SMCARI_283phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
ilvA protein networkhttps://string-db.org/network/706194.SMCARI_284Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a producti [...]
ilvC protein networkhttps://string-db.org/network/706194.SMCARI_285Ketol-acid reductoisomerase.
ilvN protein networkhttps://string-db.org/network/706194.SMCARI_286Putative acetolactate synthase small subunit.
ilvB protein networkhttps://string-db.org/network/706194.SMCARI_287Acetolactate synthase large subunit.
ilvD protein networkhttps://string-db.org/network/706194.SMCARI_288Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.