Organism Overview: Peptoniphilus sp. ING2D1G


 
dnaA protein networkhttps://string-db.org/network/1912856.ING2D1G_0001Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically doub [...]
CDZ74203.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0002DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadi [...]
CDZ74204.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0003RNA-binding protein; The S4 domain typically occurs in a single copy at various positions in different proteins. The S4 domain can be found alone as in several small bacterial proteins. or in ass [...]
recF protein networkhttps://string-db.org/network/1912856.ING2D1G_0004DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-strand [...]
gyrB protein networkhttps://string-db.org/network/1912856.ING2D1G_0005DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
gyrA protein networkhttps://string-db.org/network/1912856.ING2D1G_0006DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
CDZ74208.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0007An anti-sigma factor antagonist is an anti-anti-sigma factor, which relieves inhibition of sigma factor activity by the anti-sigma factor. Examples include the Bacillus subtilis SpoIIAA protein, [...]
CDZ74209.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0008Putative protein; Family membership.
sigB protein networkhttps://string-db.org/network/1912856.ING2D1G_0009Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma B is not essential for sporulation; rather it is requi [...]
CDZ74211.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0010Hypothetical protein; High confidence in function and specificity.
CDZ74212.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0011The HTH GntR family has many members distributed among diverse bacterial groups that regulate various biological processes. It was named GntR after the Bacillus subtilis repressor of the gluconat [...]
mtnU protein networkhttps://string-db.org/network/1912856.ING2D1G_0012The nitrilase superfamily is comprised of nitrile-or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in [...]
CDZ74214.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0013Hypothetical protein; High confidence in function and specificity.
CDZ74215.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0014TRAP-T (Tripartite ATP-independent Periplasmic Transporter) family proteins generally consist of three components, and these systems have so far been found in Gram-negative bacteria, Gram-postive [...]
CDZ74216.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0015TRAP-T family tripartite ATP-independent periplasmic transporter, membrane protein; High confidence in function and specificity.
CDZ74217.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0016TRAP-T family tripartite ATP-independent periplasmic transporter, membrane protein; The tripartite ATP-independent periplasmic (TRAP) transport system is firmly established as a new type of extra [...]
CDZ74218.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0017Putative membrane protein; This is a family of uncharacterised bacterial proteins; High confidence in function and specificity.
CDZ74219.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0018CHR family chromate ion efflux pump; This entry represents chromate transporters (CHR).These proteins reduce chromate accumulation and are essential for chromate resistance. They are composed of [...]
CDZ74220.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0019This entry represents chromate transporters (CHR). These proteins reduce chromate accumulation and are essential for chromate resistance. They are composed of one or two copies of this region. Th [...]
CDZ74221.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0020Transposase; Autonomous mobile genetic elements such as transposon or insertion sequences (IS) encode an enzyme, transposase, that is required for excising and inserting the mobile element. Trans [...]
proC protein networkhttps://string-db.org/network/1912856.ING2D1G_0021Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
CDZ74223.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_00224-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme; The family includes the protease PfpI Q51732. This domain is also found in transcriptional regulators such as Q9RJG8. This N [...]
CDZ74224.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0023L-aminopeptidase/D-esterase; This group of serine peptidases belong to MEROPS peptidase family S58 (DmpA aminopeptidase family, clan PB(S)). The protein fold of the peptidase unit for members of [...]
CDZ74225.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0024Putative membrane protein; High confidence in function and specificity.
coaX1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0025Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
CDZ74227.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0026Putative membrane protein.
CDZ74228.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0027Putative membrane protein.
CDZ74229.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0028Hypothetical protein; High confidence in function and specificity.
CDZ74230.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0029MATE efflux family protein; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range of cati [...]
CDZ74231.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0030Putative acetyltransferase, GNAT family; This entry represents a structural domain found in several acyl-CoA acyltransferase enzymes; High confidence in function and specificity.
CDZ74232.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0031Putative DNA replication protein DnaD; This entry represents a domain found in several bacterial replication initiation and membrane attachment proteins, DnaB and DnaD.The DnaD protein is a compo [...]
CDZ74233.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0032Putative DNA replication protein DnaC; High confidence in function and specificity.
CDZ74234.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0033Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes, such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the ba [...]
CDZ74235.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0034Putative membrane protein.
CDZ74236.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0035Hypothetical protein; High confidence in function and specificity.
serA1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0036D-3-phosphoglycerate dehydrogenase; High confidence in function and specificity; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
aspC protein networkhttps://string-db.org/network/1912856.ING2D1G_0037Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes, such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the ba [...]
CDZ74239.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0038Hypothetical protein.
CDZ74240.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0039Hydrolase; The PHP (Polymerase and Histidinol Phosphatase) domain is a putative phosphoesterase domain. This family is often associated with an N-terminal region; High confidence in function and [...]
CDZ74241.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0040Hypothetical protein; High confidence in function and specificity.
CDZ74242.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0041Redoxin family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection [...]
CDZ74243.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0042Pyrazinamidase; This is a family of hydrolase enzymes. Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase catalyses the conversion of isochorismate, in the presence of wate [...]
rlmH protein networkhttps://string-db.org/network/1912856.ING2D1G_0043rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
CDZ74245.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0044Transporter, CPA2 family; Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 1 [...]
CDZ74246.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0045Hypothetical protein.
CDZ74247.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0046Putative membrane protein; High confidence in function and specificity.
CDZ74248.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0047ABC transporter, permease/ATP-binding protein; High confidence in function and specificity.
CDZ74249.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0048ABC transporter, permease/ATP-binding protein; High confidence in function and specificity.
CDZ74250.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0049This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase, Phosphatidylglycerophosphatase Band bacterial acid phosphatase The family also includes a varie [...]
CDZ74251.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0050Hypothetical protein; Family membership.
CDZ74252.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0051Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
hutG protein networkhttps://string-db.org/network/1912856.ING2D1G_0052Formimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
CDZ74254.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0053Putative membrane protein.
CDZ74255.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0054Putative membrane protein.
CDZ74256.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0055Hypothetical protein; Frameshift; Family membership.
CDZ74257.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0056Hypothetical protein; Frameshift; Family membership.
CDZ74258.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0057Hypothetical protein.
CDZ74259.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0058Hypothetical protein.
CDZ74260.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0059Putative secreted protein.
CDZ74261.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0060B3/4 domain protein; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins; High confidence in function and specificity.
CDZ74262.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0061Aminotransferase class-V is an evolutionary conserved protein domain. This domain is found in amino transferases, and other enzymes including cysteine desulphurase Aminotransferases share certain [...]
CDZ74263.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0062Hypothetical protein; High confidence in function and specificity.
CDZ74264.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0063A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related. The catalytic dom [...]
agcS protein networkhttps://string-db.org/network/1912856.ING2D1G_0064Amino acid carrier protein; Sodium symporters can be divided by sequence and functional similarity into various groups. One such group is the sodium/alanine symporter family, the members of which [...]
CDZ74266.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0065Hypothetical protein.
CDZ74267.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0066Methylated-DNA-[protein]-cysteine S-methyltransferase; The major mutagenic and carcinogenic effect of methylating agents in DNA is the formation of O6-alkylguanine. The repair of DNA containing O [...]
CDZ74268.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0067Gamma-glutamyltransferase; Gamma-glutamyltranspeptidase (GGT) catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor that may be an amino acid, a peptide or water (form [...]
CDZ74269.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0068Hypothetical protein; Frameshift; Family membership.
CDZ74270.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0069Folylpolyglutamate synthase (FPGS) [1] is the enzyme of folate metabolism that catalyzes ATP-dependent addition of glutamate moieties to tetrahydrofolate; High confidence in function and specific [...]
CDZ74271.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0070Hypothetical protein; High confidence in function and specificity.
CDZ74272.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0071Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of large serine recombinases; High confidence in function and specificity.
CDZ74273.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0072Hypothetical protein.
CDZ74274.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0073The proteins in this family are found in bacteria and viruses (Caudovirales) and represent bacteriophage hypothetical proteins and capsid proteins; High confidence in function and specificity.
CDZ74275.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0074Hypothetical protein.
CDZ74276.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0075Hypothetical protein; High confidence in function and specificity.
CDZ74277.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0076Putative protein; High confidence in function and specificity.
CDZ74278.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0077Hypothetical protein.
CDZ74279.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0078Hypothetical protein; Family membership.
CDZ74280.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0079Putative transposase; Required for the transposition of the insertion element.
CDZ74281.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0080IS256 family transposase; Required for the transposition of the insertion element.
CDZ74282.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0081Hypothetical protein; High confidence in function and specificity; Belongs to the multicopper oxidase YfiH/RL5 family.
uvrB protein networkhttps://string-db.org/network/1912856.ING2D1G_0082UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnorm [...]
uvrA protein networkhttps://string-db.org/network/1912856.ING2D1G_0083UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 [...]
CDZ74285.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0084Hypothetical protein; High confidence in function and specificity.
graR protein networkhttps://string-db.org/network/1912856.ING2D1G_0085Response regulator protein GraR; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine protein kin [...]
CDZ74287.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0086Histidine kinase; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine protein kinase (HK) and a [...]
bceA protein networkhttps://string-db.org/network/1912856.ING2D1G_0087ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDZ74289.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0088Putative membrane protein.
CDZ74290.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0089Hypothetical protein; High confidence in function and specificity.
CDZ74291.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0090Hypothetical protein; High confidence in function and specificity.
CDZ74292.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0091Hypothetical protein; Family membership.
CDZ74293.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0092EDD domain protein, DegV family; High confidence in function and specificity.
CDZ74294.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0093Hypothetical protein; Family membership.
CDZ74295.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0094Aminoacyl-histidine dipeptidase; This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification. Family M20 are Glutamate carboxypeptidases. [...]
CDZ74296.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0095Hypothetical protein; High confidence in function and specificity.
CDZ74297.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0096Putative serine protease; PDZ domains (also called Discs-large homologous regions (DHR) or GLGF) are conserved structural elements of 80 to 100 amino acids that were originally identified in the [...]
CDZ74298.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0097Putative membrane protein.
CDZ74299.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0099Hypothetical protein; High confidence in function and specificity.
CDZ74300.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0100DNA alkylation repair enzyme; Proteins in this family are predicted to be DNA alkylation repair enzymes. The structure of a hypothetical protein in this family shows it to adopt a supercoiled alp [...]
CDZ74301.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0101Hypothetical protein; Family membership.
CDZ74302.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0102Hypothetical protein; High confidence in function and specificity.
CDZ74303.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0103DNA-3-methyladenine glycosylase II; This family contains a diverse range of structurally related DNA repair proteins. The superfamily is called the HhH-GPD family after its hallmark Helix-hairpin [...]
hutI2 protein networkhttps://string-db.org/network/1912856.ING2D1G_0104Imidazolonepropionase catalyzes the third step in histidine degradation. It hydrolyses the carbon-nitrogen bonds in 4-imidazolone-5-propionic acid to yield N-formimino-l-glutamic acid. The enzyme [...]
uroc1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0106Putative urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
CDZ74306.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0107DegV family protein; The structure of this protein revealed a bound fatty-acid molecule in a pocket between the two protein domains. The structure indicates that this family has the molecular fun [...]
CDZ74310.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0115Acetamidase/formamidase; This family includes amidohydrolases of formamideand acetamide; High confidence in function and specificity.
CDZ74311.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0116Glutamate formiminotransferase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool; High [...]
hutI protein networkhttps://string-db.org/network/1912856.ING2D1G_0117Imidazolonepropionase catalyzes the third step in histidine degradation. It hydrolyses the carbon-nitrogen bonds in 4-imidazolone-5-propionic acid to yield N-formimino-l-glutamic acid. The enzyme [...]
CDZ74313.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0118Putative transcriptional regulator (IclR family); The iclR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 60 amino acids present in transcription regulators of t [...]
CDZ74314.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0119Hypothetical protein; High confidence in function and specificity.
CDZ74315.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0120DHH subfamily 1 protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
rplI protein networkhttps://string-db.org/network/1912856.ING2D1G_012150S ribosomal protein L9; Binds to the 23S rRNA.
dnaC protein networkhttps://string-db.org/network/1912856.ING2D1G_0122Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
uppP protein networkhttps://string-db.org/network/1912856.ING2D1G_0123Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
CDZ74319.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0124Predicted amidohydrolase [General function prediction only]; High confidence in function and specificity.
CDZ74320.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0125Hypothetical protein; High confidence in function and specificity.
CDZ74321.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0126Putative membrane protein.
CDZ74322.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0127Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
hppA protein networkhttps://string-db.org/network/1912856.ING2D1G_0128Inorganic diphosphatase; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosph [...]
CDZ74324.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0129Putative membrane protein; High confidence in function and specificity.
CDZ74325.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0130Putative cytidylate kinase; This family includes enzymes related to cytidylate kinase; High confidence in function and specificity.
CDZ74326.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0131Putative membrane protein.
CDZ74327.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0132Putative transcriptional regulator; This domain often appears at the C terminus of PF03816, in putative members of the LytR/CpsA/Psr regulatory protein family; High confidence in function and spe [...]
CDZ74328.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0133The nitrilase superfamily is comprised of nitrile-or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in [...]
CDZ74329.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0134Hypothetical protein; High confidence in function and specificity.
CDZ74330.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0135Hypothetical protein; Family membership.
CDZ74331.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0136Hypothetical protein.
CDZ74332.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0137This family consists of the 116kDa V-type ATPase (vacuolar (H+)-ATPases) subunits, as well as V-type ATP synthase subunit i. The V-type ATPases family are proton pumps that acidify intracellular [...]
CDZ74333.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0138V-type sodium ATPase, K subunit; Transmembrane ATPases are membrane-bound enzyme complexes/ion transporters that use ATP hydrolysis to drive the transport of protons across a membrane. Some trans [...]
CDZ74334.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0139V-type proton ATPase subunit E; This family includes the vacuolar ATP synthase E subunit as well as the archaebacterial ATP synthase E subunit; Hypothetical protein.
CDZ74335.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0140V-type sodium ATP synthase subunit C; Transmembrane ATPases are membrane-bound enzyme complexes/ion transporters that use ATP hydrolysis to drive the transport of protons across a membrane. Some [...]
atpF protein networkhttps://string-db.org/network/1912856.ING2D1G_0141V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
atpA protein networkhttps://string-db.org/network/1912856.ING2D1G_0142V-ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.
atpB protein networkhttps://string-db.org/network/1912856.ING2D1G_0143V-ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
atpD protein networkhttps://string-db.org/network/1912856.ING2D1G_0144V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
CDZ74340.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0145Hypothetical protein; Family membership.
CDZ74341.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0146Hypothetical protein; High confidence in function and specificity.
CDZ74342.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0147Hypothetical protein; Family membership.
CDZ74343.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0148Na+/H+ antiporter NhaC; A single member of the NhaC family, a protein from Bacillus firmus, has been functionally characterized.It is involved in pH homeostasis and sodium extrusion. Members of t [...]
CDZ74344.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0149Hypothetical protein; Family membership.
CDZ74345.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0150Amino acid permease-associated region; High confidence in function and specificity.
CDZ74346.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0151Putative membrane protein.
CDZ74347.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0152Hypothetical protein; High confidence in function and specificity.
CDZ74349.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0154tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; High confidence in function and specificity; Belongs to the TtcA family.
exoA protein networkhttps://string-db.org/network/1912856.ING2D1G_0155Exodeoxyribonuclease; Exonucleolytic cleavage in the 3'-to 5'-direction to yield nucleoside 5'-phosphates; High confidence in function and specificity.
CDZ74351.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0156Putative family; This model summarizes an uncharacterized family of proteins; High confidence in function and specificity.
CDZ74352.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0157Putative secreted protein.
CDZ74353.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0158Hypothetical protein; Family membership.
CDZ74354.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0159Magnesium transporter; Acts as a magnesium transporter.
CDZ74355.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0160Putative D-alanyl-D-alanine carboxypeptidase; High confidence in function and specificity; Belongs to the peptidase S11 family.
CDZ74356.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0161Hypothetical protein; High confidence in function and specificity.
ftcd protein networkhttps://string-db.org/network/1912856.ING2D1G_0162Glutamate formimidoyltransferase; The formiminotransferase (FT) domain of formiminotransferase-cyclodeaminase forms a homodimer, with each protomer being comprised of two subdomains. The formimin [...]
fhs protein networkhttps://string-db.org/network/1912856.ING2D1G_0163Formate-tetrahydrofolate ligase(formyltetrahydrofolate synthetase) (FTHFS) is one of the enzymes participating in the transfer of one-carbon units, an essential element of various biosynthetic pa [...]
fchA protein networkhttps://string-db.org/network/1912856.ING2D1G_0164Enzymes containing the cyclodeaminase domain function in channeling one-carbon units to the folate pool. In most cases, this domain catalyses the cyclisation of formimidoyltetrahydrofolate to met [...]
mutL protein networkhttps://string-db.org/network/1912856.ING2D1G_0165MutL protein; This small family includes, GlmL/MutL from Clostridium tetanomorphum and Clostridium cochlearium. GlmL is located between the genes for the two subunits, epsilon (GlmE) and sigma (G [...]
CDZ74361.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0166Hypothetical protein; High confidence in function and specificity.
CDZ74362.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0167Hypothetical protein; Family membership.
CDZ74363.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0168CBS domains contain about 60 amino acid residues and occur as tandem pairs in a variety of proteins in bacteria, archaea, and eukaryotes.hey are mainly found in proteins that are regulated by ade [...]
norV protein networkhttps://string-db.org/network/1912856.ING2D1G_0169Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredo [...]
CDZ74365.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0170GntR family transcriptional regulator; Family membership.
CDZ74366.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0171ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDZ74367.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0172Putative membrane protein.
CDZ74368.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0173Putative membrane protein.
CDZ74369.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0174Putative membrane protein; High confidence in function and specificity.
CDZ74370.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0175Hypothetical protein; High confidence in function and specificity.
CDZ74371.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0176Hypothetical protein; High confidence in function and specificity.
dnaJ3 protein networkhttps://string-db.org/network/1912856.ING2D1G_0177Chaperone protein DnaJ; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaper [...]
clpB protein networkhttps://string-db.org/network/1912856.ING2D1G_0178Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to t [...]
CDZ74374.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0179Putative protein; Family membership.
serA3 protein networkhttps://string-db.org/network/1912856.ING2D1G_0180A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related. The catalytic dom [...]
serC protein networkhttps://string-db.org/network/1912856.ING2D1G_0181Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
murJ protein networkhttps://string-db.org/network/1912856.ING2D1G_0182Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
CDZ74378.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0183Sodium transporter family protein; High confidence in function and specificity; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
CDZ74379.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0184RNA polymerase sigma-70 factor; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due t [...]
CDZ74380.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0185Hypothetical protein.
fabG1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0187The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD-or NADP-dependent oxidoreductases. As the first member of this family t [...]
CDZ74382.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0188Putative membrane protein.
CDZ74383.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0189Hypothetical protein; Family membership.
CDZ74384.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0190Radical SAM proteins catalyse diverse reactions, including unusual methylations, isomerisation, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation; High confiden [...]
CDZ74385.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0191Hypothetical protein; High confidence in function and specificity.
map protein networkhttps://string-db.org/network/1912856.ING2D1G_0192Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
CDZ74387.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0193MATE efflux family protein; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range of cati [...]
CDZ74388.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0194Putative peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the [...]
CDZ74389.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0195CapA domain protein; This protein is a putative poly-gamma-glutamate capsule biosynthesis protein found in bacteria. Poly-gamma-glutamate is a natural polymer that may be involved in virulence an [...]
CDZ74390.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0196Hypothetical protein; Family membership.
CDZ74391.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0197Putative membrane protein.
CDZ74392.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0198Transcriptional regulator CtsR; This family consists of several Firmicute transcriptional repressor of class III stress genes (CtsR) proteins. CtsR of L. monocytogenes negatively regulates the cl [...]
CDZ74393.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0199Putative UvrB/uvrC protein; During the process of Escherichia coli nucleotide excision repair, DNA damage recognition and processing are achieved by the action of the uvrA, uvrB, and uvrC gene pr [...]
CDZ74394.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0200Putative ATP:guanido phosphotransferase domain protein; The substrate binding site is located in the cleft between N and C-terminal domains, but most of the catalytic residues are found in the la [...]
clpC protein networkhttps://string-db.org/network/1912856.ING2D1G_0201Negative regulator of genetic competence ClpC/MecB; High confidence in function and specificity; Belongs to the ClpA/ClpB family.
radA protein networkhttps://string-db.org/network/1912856.ING2D1G_0202DNA repair protein RadA homolog; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated [...]
CDZ74397.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0203acyl-CoA thioester hydrolase family protein; This family contains a wide variety of enzymes, principally thioesterases. This family includes 4HBT which catalyses the final step in the biosynthesi [...]
CDZ74398.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0204Putative membrane protein.
CDZ74399.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0205ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDZ74400.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0206Transcriptional regulator, GntR family; The gntR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 60-70 residues present in transcriptional regulators of the gntR [...]
CDZ74401.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0207Hypothetical protein.
nth protein networkhttps://string-db.org/network/1912856.ING2D1G_0208Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleavi [...]
CDZ74403.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0209VanW like protein; The G5 domain (named after its conserved glycine residues) is a module of 80 residues that is found in a variety of enzymes such as Streptococcal IgA peptidases and various gly [...]
CDZ74404.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0210Hypothetical protein; High confidence in function and specificity.
CDZ74405.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0211Alpha/beta hydrolase family protein; High confidence in function and specificity.
CDZ74406.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0212Hypothetical protein; Family membership.
CDZ74407.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0213ABC-type transport system, sugar-family ATP-binding protein; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological [...]
CDZ74408.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0214ABC transporter, permease protein; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological import and export systems [...]
CDZ74409.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0215ABC transporter, permease protein; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological import and export systems [...]
CDZ74410.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0216ABC-type sugar transport system, periplasmic component; Family membership.
CDZ74411.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0217Hypothetical protein; Family membership.
CDZ74412.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0218Putative membrane protein; Family membership.
CDZ74414.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0220Hypothetical protein; High confidence in function and specificity.
CDZ74415.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0221Hypothetical protein; High confidence in function and specificity.
CDZ74416.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0222Type I restriction enzyme R protein, N-terminal domain protein; Helicases have been classified in 5 superfamilies (SF1-SF5). All of the proteins bind ATP and, consequently, all of them carry the [...]
CDZ74417.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0223Hypothetical protein; Frameshift; High confidence in function and specificity.
hsdM protein networkhttps://string-db.org/network/1912856.ING2D1G_0224Type I restriction-modification system methyltransferase subunit; N-6 adenine-specific DNA methylases (A-Mtase) are enzymes that specifically methylate the amino group at the C-6 position of aden [...]
CDZ74419.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0225Hypothetical protein; Family membership.
CDZ74420.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0226Putative RNA methyltransferase; This small domain has no known function. However it may perform a nucleic acid binding role; High confidence in function and specificity; Belongs to the class I-li [...]
CDZ74421.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0227S1 RNA binding domain protein; The S1 domain of around 70 amino acids, originally identified in ribosomal protein S1, is found in a large number of RNA-associated proteins. It has been shown that [...]
CDZ74422.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0228Hypothetical protein; Family membership.
ushA protein networkhttps://string-db.org/network/1912856.ING2D1G_02292',3'-cyclic-nucleotide 2'-phosphodiesterase is a bifunctional enzyme localized to the periplasm of Gram-negative bacteria. 2',3'-cyclic-nucleotide 2'-phosphodiesters are intermediates formed dur [...]
rnfC protein networkhttps://string-db.org/network/1912856.ING2D1G_0230Electron transport complex subunit C; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxi [...]
rnfD protein networkhttps://string-db.org/network/1912856.ING2D1G_0231Electron transport complex subunit D; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.
CDZ74426.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0232Part of a membrane complex involved in electron transport; High confidence in function and specificity.
rnfE protein networkhttps://string-db.org/network/1912856.ING2D1G_0233Electron transport complex subunit E; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
rnfA protein networkhttps://string-db.org/network/1912856.ING2D1G_0234Electron transport complex subunit A; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
rnfB protein networkhttps://string-db.org/network/1912856.ING2D1G_0235Electron transport complex B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxi [...]
CDZ74430.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0236Putative membrane protein.
CDZ74431.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0237This family contains component I of bacterial heptaprenyl diphosphate synthase ((approximately 170 residues long). This is one of the two dissociable subunits that form the enzyme, both of which [...]
CDZ74432.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0238Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nu [...]
CDZ74433.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0239DNA repair proteins; UPF0758 was previously known as the radC family. The name was assigned according to the radC102 mutant of E. coli which was later demonstrated to be an allele of the transcri [...]
CDZ74434.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0240Ribonuclease E and Ribonuclease G are related enzymes that cleave a wide variety of RNAs; High confidence in function and specificity.
CDZ74435.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0241Putative arylesterase; This entry represents the SGNH hydrolase-type esterase domain, which has a similar fold to flavoproteins, namely a three-layer alpha/beta/alpha structure, where the beta-sh [...]
CDZ74436.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0242Putative membrane protein.
CDZ74437.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0243Hypothetical protein; Family membership.
CDZ74438.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0244Putative membrane protein.
CDZ74439.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0245Hypothetical protein; Family membership.
CDZ74440.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0246Putative membrane protein.
CDZ74441.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0247Transposase; High confidence in function and specificity.
CDZ74442.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0248Hypothetical protein.
efp protein networkhttps://string-db.org/network/1912856.ING2D1G_0249Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirect [...]
CDZ74444.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0250Hypothetical protein.
CDZ74445.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0251Hypothetical protein; High confidence in function and specificity.
nusB protein networkhttps://string-db.org/network/1912856.ING2D1G_0252Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator seque [...]
xseA protein networkhttps://string-db.org/network/1912856.ING2D1G_0253Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonuc [...]
xseB protein networkhttps://string-db.org/network/1912856.ING2D1G_0254Hypothetical protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs t [...]
CDZ74449.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0255Geranyltranstransferase; A variety of isoprenoid compounds are synthesized by various organisms. For example in eukaryotes the isoprenoid biosynthetic pathway is responsible for the synthesis of [...]
yqxC protein networkhttps://string-db.org/network/1912856.ING2D1G_0256Putative rRNA methyltransferase; Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; High confidence in function and specificity.
CDZ74451.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0257DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
mutT3 protein networkhttps://string-db.org/network/1912856.ING2D1G_0258ADP-ribose pyrophosphatase; The Nudix superfamily is widespread among eucaryotes, bacteria, archaea and viruses and consists mainly of pyrophosphohydrolases that act upon substrates of general st [...]
punA protein networkhttps://string-db.org/network/1912856.ING2D1G_0259Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the forma [...]
pdp protein networkhttps://string-db.org/network/1912856.ING2D1G_0260Bacterial pyrimidine-nucleoside phosphorylase (gene pdp) [3] is an enzyme evolutionary and structurally related to thymidine phosphorylase; High confidence in function and specificity.
CDZ74455.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0261Peptidase, M50 family; Metalloproteases are the most diverse of the four main types of protease, with more than 50 families identified to date. In these enzymes, a divalent cation, usually zinc, [...]
scpA protein networkhttps://string-db.org/network/1912856.ING2D1G_0262Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA awa [...]
CDZ74457.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0263Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA awa [...]
rluB protein networkhttps://string-db.org/network/1912856.ING2D1G_0264Ribosomal large subunit pseudouridine synthase B; The S4 domain typically occurs in a single copy at various positions in different proteins. The S4 domain can be found alone as in several small [...]
CDZ74459.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0265Putative rRNA methylase; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; High confidence in function an [...]
CDZ74460.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0266Putative flavoprotein; High confidence in function and specificity.
cmk protein networkhttps://string-db.org/network/1912856.ING2D1G_0267Cytidylate kinasecatalyses the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP; High confidence in function and specificity.
plsC protein networkhttps://string-db.org/network/1912856.ING2D1G_0268This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This domain is found in tafazzins, defects in which are the cause of Barth synd [...]
ispH protein networkhttps://string-db.org/network/1912856.ING2D1G_0269Putative 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and [...]
CDZ74464.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0270Hypothetical protein; Family membership; Belongs to the UPF0237 family.
CDZ74465.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0271Hypothetical protein; High confidence in function and specificity.
CDZ74466.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0272Hypothetical protein.
CDZ74467.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0273Hypothetical protein; Family membership.
CDZ74468.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0274Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from Escherichia coli; High confidence in function and [...]
CDZ74469.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0275Putative RNA polymerase sigma factor; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is [...]
entD protein networkhttps://string-db.org/network/1912856.ING2D1G_0276Proteins families containing this domain include zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-am [...]
CDZ74471.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0277Hypothetical protein; Family membership.
CDZ74472.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0278Hypothetical protein; Family membership.
CDZ74473.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0279Putative membrane protein.
CDZ74474.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0280Putative membrane protein; Family membership.
CDZ74475.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0281Hypothetical protein; Family membership.
CDZ74476.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0282Penicillin-binding protein 1A (PBP1a); The active site serine is conserved in all members of this family; High confidence in function and specificity.
CDZ74477.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0283Protein BioY; A number of bacterial genes are involved in bioconversion of pimelate into dethiobiotin. BioY is a component of the BioMNY transport system involved in biotin uptake in prokaryotes; [...]
coaX3 protein networkhttps://string-db.org/network/1912856.ING2D1G_0284Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
CDZ74479.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0285tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; [...]
greA protein networkhttps://string-db.org/network/1912856.ING2D1G_0286Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
lysS protein networkhttps://string-db.org/network/1912856.ING2D1G_0287Lysine-tRNA ligase; Aminoacyl-tRNA synthetases [1] are a group of enzymes which activate amino acids and transfer them to specific tRNA molecules as the first step in protein biosynthesis. In pro [...]
CDZ74482.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0288Hypothetical protein; Family membership.
CDZ74483.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0289Hypothetical protein; Family membership.
CDZ74484.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0290Hypothetical protein; Family membership.
CDZ74485.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0291Hypothetical protein; Family membership.
CDZ74486.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0292Hypothetical protein; Family membership.
trmB protein networkhttps://string-db.org/network/1912856.ING2D1G_0293tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
pepT protein networkhttps://string-db.org/network/1912856.ING2D1G_0301Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
CDZ74492.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0302Putative membrane protein.
CDZ74493.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0303Flavoprotein family protein; The model when searched with a partial length search brings in proteins with a dinucleotide-binding motif (Rossman fold) over the initial 40 residues of the model, in [...]
CDZ74494.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0304Putative oxidoreductase, NAD-binding; C-terminal SAF domain of an uncharacterized family of putative dehydrogenases or oxidoreductases, which are otherwise members of the NAD(P)-dependent Rossman [...]
CDZ74495.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0305BadM/Rrf2 family transcriptional regulator; The rrf2-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 130 residues present in transcription regulators of the rrf2 [...]
ileS protein networkhttps://string-db.org/network/1912856.ING2D1G_0306Isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such erro [...]
CDZ74497.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0307Phosphoserine phosphatase [Amino acid transport and metabolism]; High confidence in function and specificity.
CDZ74498.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0308Amidohydrolase; This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification. Family M20 are Glutamate carboxypeptidases. Peptidase family [...]
ahpC protein networkhttps://string-db.org/network/1912856.ING2D1G_0309Alkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role i [...]
CDZ74500.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0310O-acetylhomoserine (thiol)-lyase; High confidence in function and specificity.
metA protein networkhttps://string-db.org/network/1912856.ING2D1G_0311Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
CDZ74502.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0312Hypothetical protein; High confidence in function and specificity.
CDZ74503.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0313ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological import and export systems. ABC transporters are minimally con [...]
CDZ74504.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0314ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDZ74505.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0318Hypothetical protein; High confidence in function and specificity.
CDZ74506.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_03195-formyltetrahydrofolate cyclo-ligase or methenyl-THF synthetasecatalyses the interchange of 5-formyltetrahydrofolate (5-FTHF) to 5-10-methenyltetrahydrofolate, this requires ATP and Mg2+. 5-FTHF [...]
ftsE protein networkhttps://string-db.org/network/1912856.ING2D1G_0320Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
ftsX protein networkhttps://string-db.org/network/1912856.ING2D1G_0321Putative cell division protein FtsX; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane [...]
CDZ74509.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0322Peptidase, M23/M37 family; Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. [...]
CDZ74510.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0323Carboxy-processing protease; The enzyme shows specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is prefera [...]
CDZ74511.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0324Integral membrane protein; High confidence in function and specificity.
ytsJ protein networkhttps://string-db.org/network/1912856.ING2D1G_0325Malic enzyme, NAD binding domain protein; Malic enzymes, or malate oxidoreductases, catalyze the oxidative decarboxylation of malate into pyruvate important for a wide range of metabolic pathways [...]
tyrS protein networkhttps://string-db.org/network/1912856.ING2D1G_0326Tyrosine-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRN [...]
nnrD protein networkhttps://string-db.org/network/1912856.ING2D1G_0327Carbohydrate kinase family protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epi [...]
CDZ74515.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0328PemK-like protein; Toxic component of a type II toxin-antitoxin (TA) system.
CDZ74516.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0329Hypothetical protein; High confidence in function and specificity.
csaB protein networkhttps://string-db.org/network/1912856.ING2D1G_0330Pyruvyl-transferases are involved in peptidoglycan-associated polymer biosynthesis. CsaB in Bacillus anthracis is necessary for the non-covalent anchoring of proteins containing an SLH (S-layer h [...]
CDZ74518.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0331Putative methyltransferase type 12; Protein in this family function as methyltransferases; High confidence in function and specificity.
tagA protein networkhttps://string-db.org/network/1912856.ING2D1G_0332Glycosyl transferase, WecB/TagA/CpsF family; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis [...]
tkt protein networkhttps://string-db.org/network/1912856.ING2D1G_0333Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
CDZ74521.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0334Putative membrane protein.
guaA protein networkhttps://string-db.org/network/1912856.ING2D1G_0335GMP synthase; Catalyzes the synthesis of GMP from XMP.
CDZ74523.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0336Transcriptional regulator, MerR family; The merR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 70 residues present in the merR family of transcriptional regulat [...]
CDZ74524.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0337Transcriptional regulator; The cro/C1-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of about 50-60 residues present in transcriptional regulators. The domain is named after the [...]
CDZ74525.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0338FMN-binding domain; This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins; Family membership.
CDZ74526.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0339Putative membrane protein; Family membership.
CDZ74527.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0340Hypothetical protein; High confidence in function and specificity.
CDZ74528.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0341Putative membrane protein.
CDZ74529.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0342Type I restriction-modification system M protein; N-6 adenine-specific DNA methylases (A-Mtase) are enzymes that specifically methylate the amino group at the C-6 position of adenines in DNA. Suc [...]
CDZ74530.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0343This enzyme has been characterized and shown to belong to a new family of the type I class of restriction and modification enzymes. This family is involved in bacterial defence by making double s [...]
CDZ74531.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0344This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domai [...]
CDZ74532.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0345TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; High confidence in function and specificity.
CDZ74533.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0346Putative membrane protein.
CDZ74534.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0347TRAP dicarboxylate transporter; High confidence in function and specificity.
CDZ74535.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0348Nitrilases; This subgroup includes mammalian Nit1 and Nit2, the Nit1-like domain of the invertebrate NitFhit, and various uncharacterized bacterial and archaeal Nit-like proteins. Nit1 and Nit2 a [...]
CDZ74536.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0349Members of this family are demethylmenaquinone methyltransferases that convert dimethylmenaquinone (DMK) to menaquinone (MK) in the final step of menaquinone biosynthesis. This region is also fou [...]
CDZ74537.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0350Hypothetical protein.
CDZ74538.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0351Hypothetical protein.
CDZ74540.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0354TRAP transporter; Tripartite ATP-independent periplasmic transporters (TRAP transporters) are a large family of solute transporters found in bacteria and archaea, but not in eukaryotes, that appe [...]
CDZ74541.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0355TRAP transporter solute receptor; This family contains the NMT1 and THI5 proteins. These proteins are proposed to be required for the biosynthesis of the pyrimidine moiety of thiamine [1]. They a [...]
CDZ74542.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0357Putative transcriptional regulator, GntR family; The GntR-like bacterial transcription factors are a family of transcription factors; High confidence in function and specificity.
CDZ74543.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0358Aspartokinase (AK) [1] catalyzes the phosphorylation of aspartate. The product of this reaction can then be used in the biosynthesis of lysine or in the pathway leading to homoserine, which parti [...]
CDZ74544.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0359Hypothetical protein; Family membership.
metN2 protein networkhttps://string-db.org/network/1912856.ING2D1G_0360Methionine import ATP-binding protein MetN 2; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
metI protein networkhttps://string-db.org/network/1912856.ING2D1G_0361ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological import and export systems (see <PDOC00185>). ABC transporters [...]
metQ protein networkhttps://string-db.org/network/1912856.ING2D1G_0362This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system; High confidence in function and specificity; Belongs to the nlpA lipoprotein fami [...]
polA protein networkhttps://string-db.org/network/1912856.ING2D1G_0364DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
coaE protein networkhttps://string-db.org/network/1912856.ING2D1G_0365dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
CDZ74550.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0366Glutamate synthase (NADPH), homotetrameric; One pathway for the assimilation of ammonia and glutamate biosynthesis involves homotetrameric glutamate synthase which transfers the amide group of gl [...]
proB protein networkhttps://string-db.org/network/1912856.ING2D1G_0367Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
proA protein networkhttps://string-db.org/network/1912856.ING2D1G_0368Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclizat [...]
CDZ74553.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0369Threonine synthase; This domain is found at the N-terminus of many threonine synthase enzymes; High confidence in function and specificity.
thrB protein networkhttps://string-db.org/network/1912856.ING2D1G_0370Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
CDZ74556.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0372Hypothetical protein; Family membership.
CDZ74557.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0373Hypothetical protein; High confidence in function and specificity.
CDZ74558.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0374YbaK/proline-tRNA ligase associated domain protein; This domain is found either on its own or in association with the tRNA synthetase class II core domain (PF00587). It is involved in the tRNA ed [...]
murJ-2 protein networkhttps://string-db.org/network/1912856.ING2D1G_0375Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
CDZ74560.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0376ABC transporter, permease/ATP-binding protein; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological import and exp [...]
CDZ74561.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0377Hypothetical protein; High confidence in function and specificity.
CDZ74562.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0378Pseudouridine synthase, RluA family; Members of this family are involved in modifying bases in RNA molecules. They carry out the conversion of uracil bases to pseudouridine. This family includes [...]
CDZ74563.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0379Hypothetical protein; Family membership.
CDZ74564.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0380UvrD/REP helicase subfamily; ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily.
copA protein networkhttps://string-db.org/network/1912856.ING2D1G_0381Putative copper-importing P-type ATPase A; High confidence in function and specificity.
CDZ74566.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0382Acetyl-CoA hydrolase/transferase C-terminal domain; This family contains several enzymes which take part in pathways involving acetyl-CoA. Acetyl-CoA hydrolasecatalyses the formation of acetate f [...]
ywdH protein networkhttps://string-db.org/network/1912856.ING2D1G_0383His family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor. The family includes the following members: The prototypical members are the aldehyde dehydrogenases P00352 [...]
CDZ74568.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0384Glycosyl transferase, group 1 family; Mutations in this domain of P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of s [...]
CDZ74569.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0385This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building, bidirectional best hits and one-to-a-genome distribution, to represent a co [...]
CDZ74570.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0386Hypothetical protein; Family membership.
CDZ74571.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0387TRAP transporter solute receptor; TRAP-type uncharacterized transport system, periplasmic component [General function prediction only]; Family membership.
CDZ74572.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0388TRAP transporter 4TM/12TM fusion protein; Tripartite ATP-independent periplasmic transporters (TRAP transporters) are a large family of solute transporters found in bacteria and archaea, but not [...]
CDZ74573.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0389Hypothetical protein; High confidence in function and specificity.
rplU protein networkhttps://string-db.org/network/1912856.ING2D1G_0390Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
CDZ74575.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0391Hypothetical protein.
rpmA protein networkhttps://string-db.org/network/1912856.ING2D1G_0392L27 is a protein from the large (50S) subunit; it is essential for ribosome function, but its exact role is unclear. It belongs to a family of ribosomal proteins, examples of which are found in b [...]
obg protein networkhttps://string-db.org/network/1912856.ING2D1G_0393GTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in contro [...]
CDZ74578.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0394Hypothetical protein; Family membership.
nadD protein networkhttps://string-db.org/network/1912856.ING2D1G_0395Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
CDZ74580.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0396HD superfamily hydrolase; Metal dependent phosphohydrolases with conserved 'HD' motif; High confidence in function and specificity.
CDZ74581.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0397Transcriptional regulator [Transcription]; High confidence in function and specificity.
rsfS protein networkhttps://string-db.org/network/1912856.ING2D1G_0398Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the [...]
CDZ74583.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0399Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation; High confidence in function and specif [...]
CDZ74584.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0400Putative ribosomal protein L7Ae-like; Provisional; Family membership.
rpsL protein networkhttps://string-db.org/network/1912856.ING2D1G_040130S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S an [...]
rpsG protein networkhttps://string-db.org/network/1912856.ING2D1G_040230S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
fusA protein networkhttps://string-db.org/network/1912856.ING2D1G_0403Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
tuf1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0404Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
acoA protein networkhttps://string-db.org/network/1912856.ING2D1G_0405Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2; High confidence in function and specifici [...]
acoB protein networkhttps://string-db.org/network/1912856.ING2D1G_0406Pyruvate dehydrogenase E1 component subunit alpha; Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine <=> [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoy [...]
CDZ74591.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0407NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydr [...]
acoC protein networkhttps://string-db.org/network/1912856.ING2D1G_0408Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Biotin and lipoic acid moieties are the covalently bound cofactors of several multicomponent enzyme complexes that [...]
acoL protein networkhttps://string-db.org/network/1912856.ING2D1G_0409TPP-dependent acetoin dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase; Protein N(6)-(dihydrolipoyl)lysine + NAD+ = protein N(6)-(lipoyl)lysine + NADH; High confidence in funct [...]
lplA protein networkhttps://string-db.org/network/1912856.ING2D1G_0410Lipoate-protein ligase A (octanoyltransferase) catalyses the formation of an amide linkage between lipoic acid and a specific lysine residue in lipoate dependent enzymes; High confidence in funct [...]
CDZ74595.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0411Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes, such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the ba [...]
CDZ74596.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0412Hypothetical protein; Family membership.
CDZ74597.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0413Putative membrane protein.
CDZ74598.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0414Hypothetical protein; High confidence in function and specificity.
CDZ74599.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0415Glutaredoxins are small redox enzymes of approximately one hundred amino-acid residues that use glutathione as a cofactor. Glutaredoxins are oxidized by substrates, and reduced non-enzymatically [...]
CDZ74600.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0416Glutaredoxin, also known as thioltransferase, is a small protein of approximately one hundred amino-acid residues. It functions as an electron carrier in the glutathione-dependent synthesis of de [...]
CDZ74601.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0417Hypothetical protein; Family membership.
CDZ74602.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0418The alpha/beta hydrolase fold is common to a number of hydrolytic enzymes of widely differing phylogenetic origin and catalytic function. The core of each enzyme is an alpha/beta-sheet (rather th [...]
CDZ74603.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0419UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murei [...]
ddl protein networkhttps://string-db.org/network/1912856.ING2D1G_0420D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
rnr protein networkhttps://string-db.org/network/1912856.ING2D1G_0421Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
smpB protein networkhttps://string-db.org/network/1912856.ING2D1G_0422SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
ribD protein networkhttps://string-db.org/network/1912856.ING2D1G_0423Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-termi [...]
ribE protein networkhttps://string-db.org/network/1912856.ING2D1G_0424Riboflavin synthase, which contains two homologous domains of this structure.Riboflavin synthase catalyses the final step in the biosynthesis of vitamin B2, namely the dismutation of two molecule [...]
ribBA protein networkhttps://string-db.org/network/1912856.ING2D1G_0425Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cycloh [...]
ribH protein networkhttps://string-db.org/network/1912856.ING2D1G_04266,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
CDZ74611.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0427Putative phosphatase; High confidence in function and specificity.
CDZ74612.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0428Hypothetical protein.
CDZ74613.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0429Putative MutS domain protein; Mismatch repair contributes to the overall fidelity of DNA replication and is essential for combating the adverse effects of damage to the genome. It involves the co [...]
CDZ74614.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_04303-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cy [...]
CDZ74615.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0431HAD-superfamily hydrolase, subfamily IB; The haloacid dehydrogenase (HAD) superfamily includes phosphatases, phosphonatases, P-type ATPases, beta-phosphoglucomutases, phosphomannomutases, and deh [...]
dinB protein networkhttps://string-db.org/network/1912856.ING2D1G_0432DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misa [...]
apt protein networkhttps://string-db.org/network/1912856.ING2D1G_0433Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
CDZ74618.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0434Hypothetical protein; Family membership.
CDZ74619.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0436Putative membrane protein.
CDZ74620.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0437Hypothetical protein.
CDZ74621.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0438ErfK/YbiS/YcfS/YnhG superfamily protein; This family was formerly called the ErfK/YbiS/YcfS/YnhG family, but is now named after the first protein of known structure.So these proteins may use pept [...]
CDZ74622.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0439Putative membrane protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-trans [...]
rplY protein networkhttps://string-db.org/network/1912856.ING2D1G_044050S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
mnmA1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0441tRNA-specific 2-thiouridylase MnmA 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
CDZ74625.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0442Thiamin biosynthesis lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavopr [...]
CDZ74626.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0443Putative membrane protein; High confidence in function and specificity.
nucH protein networkhttps://string-db.org/network/1912856.ING2D1G_0444Thermonuclease; Staphylococcus aureus secretes a thermostable nuclease, known as thermonuclease (TNase) or staphylococcal nuclease (SNase), which is a calcium-dependent enzyme that catalyzes the [...]
CDZ74628.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0445This family represents a family of bacterial phosphatidylglycerophosphatases (, known as PgpA. It appears that bacteria possess several phosphatidylglycerophosphatases, and thus, PgpA is not esse [...]
CDZ74629.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0446Putative SAM-dependent methyltransferase; This domain is found in ribosomal RNA small subunit methyltransferase C and in other methyltransferases; High confidence in function and specificity; Bel [...]
rsmI protein networkhttps://string-db.org/network/1912856.ING2D1G_0447Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
CDZ74631.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0448NurA domain protein; This domain is found in several uncharacterised proteins and in NurA, a nuclease exhibiting both single-stranded endonuclease activity and 5'-3' exonuclease activity on singl [...]
CDZ74632.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0449Hypothetical protein; High confidence in function and specificity.
nhaC protein networkhttps://string-db.org/network/1912856.ING2D1G_0450NhaC family sodium:proton (Na+:H+) antiporter; High confidence in function and specificity.
CDZ74635.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0452Hemolysin III; Members of this family are integral membrane proteins. This family includes a protein with hemolytic activity from Bacillus cereus. It has been proposed that YOL002c encodes a Sacc [...]
secA protein networkhttps://string-db.org/network/1912856.ING2D1G_0453Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the [...]
CDZ74637.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0454ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; High confidence in function and specificity.
oppB protein networkhttps://string-db.org/network/1912856.ING2D1G_0455Oligopeptide transport system permease protein OppB; High confidence in function and specificity.
dppC protein networkhttps://string-db.org/network/1912856.ING2D1G_0456Dipeptide transport system permease protein DppC; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane do [...]
oppD protein networkhttps://string-db.org/network/1912856.ING2D1G_0457Oligopeptide transport ATP-binding protein OppD; High confidence in function and specificity; Belongs to the ABC transporter superfamily.
CDZ74641.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0458Oligopeptide ABC transporter ATP-binding protein OppF; Provisional; High confidence in function and specificity; Belongs to the ABC transporter superfamily.
CDZ74642.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0459butyryl-CoA dehydrogenase; Butanoyl-CoA + electron-transfer flavoprotein <=> 2-butenoyl-CoA + reduced electron-transfer flavoprotein; High confidence in function and specificity.
CDZ74643.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0460Putative flavoproteins; High confidence in function and specificity.
CDZ74644.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0461Transporter, auxin efflux carrier (AEC) family; High confidence in function and specificity.
CDZ74645.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0462Putative membrane protein.
CDZ74646.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0463Hypothetical protein; High confidence in function and specificity.
CDZ74647.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0464Glutamate-cysteine ligase family 2(GCS2); Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
CDZ74648.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0465Hypothetical protein; Family membership.
CDZ74649.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0466Putative secreted protein.
dnaX protein networkhttps://string-db.org/network/1912856.ING2D1G_0467DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' [...]
CDZ74651.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0468DNA-binding protein, YbaB/EbfC family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
recR protein networkhttps://string-db.org/network/1912856.ING2D1G_0469Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
ftsH1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0470ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral memb [...]
CDZ74654.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0471Hypothetical protein.
CDZ74655.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0472Putative transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N-and C-terminus respectively. The transglycosylase d [...]
hflX protein networkhttps://string-db.org/network/1912856.ING2D1G_0473GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPa [...]
CDZ74657.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0474Hypothetical protein; High confidence in function and specificity.
nadE protein networkhttps://string-db.org/network/1912856.ING2D1G_0475NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
CDZ74659.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0476Hypothetical protein; Family membership.
CDZ74660.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0477This family contains many hypothetical proteins and some ABC transporter substrate binding proteins; High confidence in function and specificity.
CDZ74661.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0478ABC superfamily ATP binding cassette transporter, binding protein; High confidence in function and specificity.
CDZ74662.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0479ABC superfamily ATP binding cassette transporter, membrane protein; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as Escherichia coli [...]
CDZ74663.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0480ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
brnQ protein networkhttps://string-db.org/network/1912856.ING2D1G_0481Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.
pycB protein networkhttps://string-db.org/network/1912856.ING2D1G_0482Pyruvate carboxylase subunit B; Oxaloacetate <=> pyruvate + CO(2); High confidence in function and specificity.
fusA2 protein networkhttps://string-db.org/network/1912856.ING2D1G_0483Elongation factor G 2; This domain includes the carboxyl terminal regions of Elongation factor G, elongation factor 2 and some tetracycline resistance proteins and adopt a ferredoxin-like fold; H [...]
CDZ74667.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0484Hypothetical protein; High confidence in function and specificity.
CDZ74668.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0485LysR transcriptional regulator; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
CDZ74669.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0486Hypothetical protein; Frameshift; Family membership.
CDZ74670.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0487D-3-phosphoglycerate dehydrogenase; 3-phospho-D-glycerate + NAD(+) <=> 3-phosphonooxypyruvate + NADH, 2-hydroxyglutarate + NAD(+) <=> 2-oxoglutarate + NADH; High confidence in function and specif [...]
ispE protein networkhttps://string-db.org/network/1912856.ING2D1G_04884-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
CDZ74672.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0489Hypothetical protein; Family membership.
CDZ74673.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0490Hypothetical protein; High confidence in function and specificity.
CDZ74674.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0491Putative DnaJ domain protein; High confidence in function and specificity.
queH protein networkhttps://string-db.org/network/1912856.ING2D1G_0494Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr [...]
asd protein networkhttps://string-db.org/network/1912856.ING2D1G_0495Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the as [...]
CDZ74677.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0496L-homoserine + NAD(P)+ = L-aspartate 4-semialdehyde + NAD(P)H; High confidence in function and specificity.
CDZ74678.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0497Glycolate + NAD(+) <=> glyoxylate + NADH; High confidence in function and specificity; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
CDZ74679.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0498Ribose 5-phosphate isomerase forms a homodimer and catalyses the interconversion of D-ribose 5-phosphate and D-ribulose 5-phosphate in the non-oxidative branch of the pentose phosphate pathway. T [...]
CDZ74680.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0499Hypothetical protein; High confidence in function and specificity; Belongs to the glycosyl hydrolase 26 family.
lysC protein networkhttps://string-db.org/network/1912856.ING2D1G_0500Aspartokinase; Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to [...]
dapA protein networkhttps://string-db.org/network/1912856.ING2D1G_05014-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
dapB protein networkhttps://string-db.org/network/1912856.ING2D1G_0502Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
ddh protein networkhttps://string-db.org/network/1912856.ING2D1G_0503Diaminopimelate D-dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compo [...]
CDZ74685.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0504Putative membrane protein; Family membership.
CDZ74686.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0505Putative membrane protein.
CDZ74687.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0506Putative membrane protein; High confidence in function and specificity.
CDZ74688.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0507ABC transporter-like protein; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are m [...]
glnN protein networkhttps://string-db.org/network/1912856.ING2D1G_0508Glutamine synthetase (GS) plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine; High confidence in function and specific [...]
pyrG protein networkhttps://string-db.org/network/1912856.ING2D1G_0509CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the fo [...]
CDZ74691.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0510The Nudix family is a protein family of phosphohydrolases.Using water-mediated catalysis they break a phosphate bond in their substrate to create two products. Nudix stands for Nucleoside Diphosp [...]
cysS protein networkhttps://string-db.org/network/1912856.ING2D1G_0511Cysteine-tRNA ligase; ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys); High confidence in function and specificity; Belongs to the class-I aminoacyl-tRNA synthetase famil [...]
mrnC protein networkhttps://string-db.org/network/1912856.ING2D1G_0512Ribonuclease III domain; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc proc [...]
thyX protein networkhttps://string-db.org/network/1912856.ING2D1G_0513Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofol [...]
CDZ74695.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0514RNA methyltransferase, TrmH family, group 3; The TrmH family of RNA methyltransferases are involved in rRNA base modification; High confidence in function and specificity; Belongs to the class IV [...]
CDZ74696.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0515RNA-binding protein; High confidence in function and specificity.
ppnK protein networkhttps://string-db.org/network/1912856.ING2D1G_0516NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of [...]
CDZ74698.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0517Putative general stress protein; High confidence in function and specificity.
CDZ74699.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0518Hypothetical protein; High confidence in function and specificity.
CDZ74700.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0519The DAG-kinase catalytic domain or DAGKc domain is present in mammalian lipid kinases, such as diacylglycerol (DAG), ceramide and sphingosine kinases, as well as in related bacterial proteins; Hi [...]
CDZ74701.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0520Transcriptional regulators [Transcription]; High confidence in function and specificity.
CDZ74702.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0521Two component transcriptional regulator, LuxR family; Family membership.
secE protein networkhttps://string-db.org/network/1912856.ING2D1G_0544Putative membrane protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
nusG protein networkhttps://string-db.org/network/1912856.ING2D1G_0545Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination.
rplK protein networkhttps://string-db.org/network/1912856.ING2D1G_054650S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
rplA protein networkhttps://string-db.org/network/1912856.ING2D1G_054750S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
CDZ74710.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0548Putative peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection [...]
glpK protein networkhttps://string-db.org/network/1912856.ING2D1G_0549Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
rplJ protein networkhttps://string-db.org/network/1912856.ING2D1G_0550Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein [...]
rplL protein networkhttps://string-db.org/network/1912856.ING2D1G_0551Hypothetical protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial [...]
pyrB protein networkhttps://string-db.org/network/1912856.ING2D1G_0552Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase f [...]
CDZ74715.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0553Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase; High confidence in function and specificity.
CDZ74716.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0554Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the u [...]
pyrD protein networkhttps://string-db.org/network/1912856.ING2D1G_0555Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
whiA protein networkhttps://string-db.org/network/1912856.ING2D1G_0556Putative sporulation transcription regulator WhiA; Involved in cell division and chromosome segregation.
CDZ74719.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0557Putative Phosphotransferase; The HPr family are bacterial proteins (or domains of proteins) which function in phosphoryl transfer system (PTS) systems. They include energy-coupling components whi [...]
dnaE protein networkhttps://string-db.org/network/1912856.ING2D1G_0558DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain [...]
pfkA protein networkhttps://string-db.org/network/1912856.ING2D1G_05596-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
CDZ74722.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0560Choloylglycine hydrolase family protein; This entry includes acid ceramidases, which hydrolyse sphingolipid ceramide into sphingosine and free fatty acid. It also represents the peptidase C59 fam [...]
CDZ74723.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0561Hypothetical protein; High confidence in function and specificity.
CDZ74724.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0562Putative sodium-dependent transporter; High confidence in function and specificity.
argG protein networkhttps://string-db.org/network/1912856.ING2D1G_0563Argininosuccinate synthase (AS) is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinat [...]
argH protein networkhttps://string-db.org/network/1912856.ING2D1G_0564Argininosuccinate lyase; Arginosuccinase, which catalyzes the formation of arginine and fumarate from argininosuccinate, the last step in the biosynthesis of arginine; High confidence in function [...]
CDZ74727.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0565Transcriptional regulator [Transcription]; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
CDZ74728.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0566This family consists of fumarylacetoacetate (FAA) hydrolase, or fumarylacetoacetate hydrolase (FAH) and it also includes HHDD isomerase/OPET decarboxylase from E. coli strain W. FAA is the last e [...]
CDZ74729.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_05673-oxoacyl-[acyl-carrier-protein] reductase; Reaction catalysed, (3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) <=> 3-oxoacyl-[acyl-carrier-protein] + NADPH; High confidence in function and s [...]
gtaB protein networkhttps://string-db.org/network/1912856.ING2D1G_0568UTP-glucose-1-phosphate uridylyltransferase; Catalyzes the formation of UDP-glucose from glucose-1-phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol [...]
CDZ74731.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0569HD domains are metal dependent phosphohydrolases; High confidence in function and specificity.
resD protein networkhttps://string-db.org/network/1912856.ING2D1G_0570Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration; High [...]
CDZ74733.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0571Integral membrane sensor signal transduction histidine kinase; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved compo [...]
mraZ protein networkhttps://string-db.org/network/1912856.ING2D1G_0572Transcriptional regulator; This entry represents the 70 amino acid region found duplicated in the bacterial proteins MraZ. These proteins may be DNA-binding transcription factors, its members are [...]
rsmH protein networkhttps://string-db.org/network/1912856.ING2D1G_0573Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
CDZ74736.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0574Hypothetical protein; Family membership.
CDZ74737.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0575Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; High confidence in function and specificity.
mraY protein networkhttps://string-db.org/network/1912856.ING2D1G_0576Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...]
murD protein networkhttps://string-db.org/network/1912856.ING2D1G_0577UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF f [...]
CDZ74740.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0578Cell division protein FtsW; A number of prokaryotic integral membrane proteins involved in cell cycle processes have been found to be structurally related. These proteins include, the Escherichia [...]
murG protein networkhttps://string-db.org/network/1912856.ING2D1G_0579Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
CDZ74742.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0580Cell division protein FtsQ; Essential cell division protein.
ftsZ protein networkhttps://string-db.org/network/1912856.ING2D1G_0581Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
nrdR protein networkhttps://string-db.org/network/1912856.ING2D1G_0582Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
yrvN protein networkhttps://string-db.org/network/1912856.ING2D1G_0583Putative AAA domain-containing protein YrvN; The AAA+ superfamily of ATPases is found in all kingdoms of living organisms where they participate in diverse cellular processes including membrane f [...]
CDZ74746.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0584Putative dipeptidase B; High confidence in function and specificity.
asnS protein networkhttps://string-db.org/network/1912856.ING2D1G_0585Asparagine-tRNA ligase; Aminoacyl-tRNA synthetases are a group of enzymes which activate amino acids and transfer them to specific tRNA molecules as the first step in protein biosynthesis. In pro [...]
leuS protein networkhttps://string-db.org/network/1912856.ING2D1G_0586Leucine-tRNA ligase is an alpha monomer that belongs to class Ia. The crystal structure of leucine-tRNA ligase from the hyperthermophile Thermus thermophilus has an overall architecture that is; [...]
CDZ74749.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0587Hypothetical protein; High confidence in function and specificity.
gmk protein networkhttps://string-db.org/network/1912856.ING2D1G_0588Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
rpoZ protein networkhttps://string-db.org/network/1912856.ING2D1G_0589Putative DNA-directed RNA polymerase; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha su [...]
CDZ74752.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0590Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoyl [...]
priA protein networkhttps://string-db.org/network/1912856.ING2D1G_0591Primosomal protein N`; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its [...]
def protein networkhttps://string-db.org/network/1912856.ING2D1G_0592Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
fmt protein networkhttps://string-db.org/network/1912856.ING2D1G_0593Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
CDZ74756.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0594Hypothetical protein; High confidence in function and specificity.
CDZ74757.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0595Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
rlmN protein networkhttps://string-db.org/network/1912856.ING2D1G_0596Putative dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. [...]
CDZ74759.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0597Protein phosphatase 2C (PP2C) is one of the four major classes of mammalian serine/threonine specific protein phosphatases. PP2C is a monomeric enzyme of about 42 kDa, that shows broad substrate [...]
CDZ74760.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0598[a protein]-serine/threonine phosphate + H(2)O <=> [a protein]-serine/threonine + phosphate; High confidence in function and specificity.
rsgA protein networkhttps://string-db.org/network/1912856.ING2D1G_0599Putative ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subu [...]
CDZ74762.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0600Ribulose-phosphate 3-epimerase; D-ribulose 5-phosphate = D-xylulose 5-phosphate; High confidence in function and specificity; Belongs to the ribulose-phosphate 3-epimerase family.
CDZ74763.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0601Thiamine diphosphokinase; Thiamin pyrophosphokinase (TPK, catalyzes the transfer of a pyrophosphate group from ATP to vitamin B1 (thiamin) to form the coenzyme thiamin pyrophosphate (TPP). Thus, [...]
CDZ74764.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0602Putative membrane protein.
dacA protein networkhttps://string-db.org/network/1912856.ING2D1G_0603Protein of hypothetical; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
CDZ74766.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0604Putative membrane protein.
guaB protein networkhttps://string-db.org/network/1912856.ING2D1G_0605Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesi [...]
CDZ74768.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0606Alpha/beta hydrolase; High confidence in function and specificity.
CDZ74769.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0607Hypothetical protein; Family membership.
phoP protein networkhttps://string-db.org/network/1912856.ING2D1G_0608DNA-binding response regulator; This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain; High c [...]
CDZ74771.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0609Sensor histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine; High confidence in function and specificity.
CDZ74772.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0610Putative secreted protein.
CDZ74773.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0611Putative membrane protein; Family membership.
CDZ74774.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0612Putative endonuclease.
recX protein networkhttps://string-db.org/network/1912856.ING2D1G_0613Putative RecX protein; Modulates RecA activity; Belongs to the RecX family.
CDZ74776.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0614The forkhead-associated (FHA) domain is a putative nuclear signalling domain found in a variety of otherwise unrelated proteins. The FHA domain comprise approximately 55 to 75 amino acids and con [...]
CDZ74777.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0615Cell cycle protein; A number of prokaryotic integral membrane proteins involved in cell cycle processes have been found to be structurally related. These proteins include, the Escherichia coli an [...]
ftsI protein networkhttps://string-db.org/network/1912856.ING2D1G_0616Cell division protein FtsI/penicillin-binding protein 2; High confidence in function and specificity.
ispD protein networkhttps://string-db.org/network/1912856.ING2D1G_06172-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
ispF protein networkhttps://string-db.org/network/1912856.ING2D1G_06182-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
tal protein networkhttps://string-db.org/network/1912856.ING2D1G_0619Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
glpX protein networkhttps://string-db.org/network/1912856.ING2D1G_0620Fructose-1,6-bisphosphatase class 2; High confidence in function and specificity.
rho protein networkhttps://string-db.org/network/1912856.ING2D1G_0621Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
CDZ74784.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_062223S rRNA methyltransferase; High confidence in function and specificity.
CDZ74785.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0623Hypothetical protein; High confidence in function and specificity.
thrS protein networkhttps://string-db.org/network/1912856.ING2D1G_0624Threonine-tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end o [...]
CDZ74787.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0625Acetamidase/formamidase; This family includes amidohydrolases of formamideand acetamide. Q50228 forms a homotrimer suggesting all the members of this family also do; High confidence in function a [...]
CDZ74788.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0626Putative membrane protein.
CDZ74789.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0627Putative membrane protein.
CDZ74790.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0628This family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes. This family is also known as the FUR family; Fami [...]
CDZ74791.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0629ABC-type metal ion transport system; High confidence in function and specificity; Belongs to the bacterial solute-binding protein 9 family.
CDZ74792.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0630ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDZ74793.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0631ABC transporter, permease protein; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily, which uses the hydrolysis of ATP to energise diverse biological systems. ABC transporters [...]
CDZ74794.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0632Hypothetical protein; Family membership.
pgm protein networkhttps://string-db.org/network/1912856.ING2D1G_0633Phosphoglucomutase; Catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i. [...]
CDZ74796.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0634Putative Fructose-1-phosphate kinase; High confidence in function and specificity.
CDZ74797.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0635YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and sha [...]
CDZ74798.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0636Putative Ser/Thr protein phosphatase family protein; Predicted phosphohydrolases [General function prediction only]; High confidence in function and specificity.
CDZ74799.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0637Hypothetical protein; Family membership.
CDZ74800.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0638Ser/Thr protein phosphatase family protein; High confidence in function and specificity.
CDZ74801.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0639Adenylate cyclase; ATP <=> 3',5'-cyclic AMP + diphosphate; High confidence in function and specificity.
ppsA protein networkhttps://string-db.org/network/1912856.ING2D1G_0640Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
CDZ74803.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0641Hypothetical protein; High confidence in function and specificity.
CDZ74804.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0642Hypothetical protein; High confidence in function and specificity.
CDZ74805.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0643Fibronectin-binding protein; High confidence in function and specificity.
CDZ74806.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0644Transcriptional regulatory protein; High confidence in function and specificity.
CDZ74807.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0645Sensor histidine kinase; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine protein kinase (HK) [...]
CDZ74808.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0646This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyses the catabolism of glyci [...]
CDZ74809.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0647Hypothetical protein; Family membership.
CDZ74810.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0648Hypothetical protein; Family membership.
CDZ74811.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0649Hypothetical protein.
CDZ74812.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0650Hypothetical protein; High confidence in function and specificity.
cobB2 protein networkhttps://string-db.org/network/1912856.ING2D1G_0651NAD-dependent protein deacetylases, SIR2 family [Transcription]; High confidence in function and specificity.
CDZ74814.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0652Methyltransferase; High confidence in function and specificity.
hslO protein networkhttps://string-db.org/network/1912856.ING2D1G_065333 kDa chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial [...]
rpmB protein networkhttps://string-db.org/network/1912856.ING2D1G_0656The ribosomal 28 family includes L28 proteins from bacteria and chloroplasts. The L24 protein from yeast also contains a region of similarity to prokaryotic L28 proteins. L24 from yeast is also f [...]
asp protein networkhttps://string-db.org/network/1912856.ING2D1G_0657Alkaline shock protein; High confidence in function and specificity.
CDZ74818.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0658DAK2 domain protein; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family; High confidence in function and specificity.
recG protein networkhttps://string-db.org/network/1912856.ING2D1G_0659ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwindin [...]
CDZ74820.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0660RNA methyltransferase, RsmD family; High confidence in function and specificity.
coaD protein networkhttps://string-db.org/network/1912856.ING2D1G_0661Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial Co [...]
CDZ74822.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0662Hypothetical protein; High confidence in function and specificity.
tmcAL protein networkhttps://string-db.org/network/1912856.ING2D1G_0663Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to [...]
ackA protein networkhttps://string-db.org/network/1912856.ING2D1G_0664Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
CDZ74825.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0665Hypothetical protein; High confidence in function and specificity.
rpmF protein networkhttps://string-db.org/network/1912856.ING2D1G_066650S ribosomal protein L32; Ribosomes are the particles that catalyse mRNA-directed protein synthesis in all organisms. The codons of the mRNA are exposed on the ribosome to allow tRNA binding. Th [...]
CDZ74827.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0667Putative transcriptional regulatory protein; High confidence in function and specificity.
CDZ74828.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0668Multimeric flavodoxin domain containing protein; High confidence in function and specificity.
deoC protein networkhttps://string-db.org/network/1912856.ING2D1G_0669Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB ald [...]
lgt protein networkhttps://string-db.org/network/1912856.ING2D1G_0670Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
CDZ74831.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0671Putative Ser/Thr protein phosphatase family protein; Predicted phosphohydrolases [General function prediction only]; High confidence in function and specificity.
CDZ74832.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0672Aminopeptidase II; This group of metallopeptidases belong to MEROPS peptidase family M29 (aminopeptidase T family, clan M-). The protein fold of the peptidase domain and the active site residues [...]
CDZ74833.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0673Competence protein; High confidence in function and specificity.
CDZ74834.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0675Integrase family protein; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine re [...]
CDZ74835.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0676Hypothetical protein; High confidence in function and specificity.
CDZ74836.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0677Protein involved in cell division [Cell division and chromosome partitioning]; High confidence in function and specificity.
CDZ74837.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0678LexA protein; SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; High confidence in function and specificity.
CDZ74838.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0679Hypothetical protein; Family membership.
CDZ74839.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0680Putative transcriptional regulator; Family membership.
CDZ74840.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0681Putative secreted protein.
CDZ74841.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0682Hypothetical protein.
CDZ74842.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0683Hypothetical protein; Family membership.
CDZ74843.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0684Hypothetical protein; Family membership.
CDZ74844.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0685Hypothetical protein; Family membership.
CDZ74845.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0686Hypothetical protein.
CDZ74846.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0687Bacteriophage Mu Gam like protein; This family consists of bacterial and phage Gam proteins. The gam gene of bacteriophage Mu encodes a protein which protects linear double stranded DNA from exon [...]
CDZ74847.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0688Hypothetical protein; High confidence in function and specificity.
CDZ74848.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0689Hypothetical protein; Family membership.
CDZ74849.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0690Hypothetical protein; Family membership.
CDZ74850.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0691Hypothetical protein.
CDZ74851.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0692Hypothetical protein; Family membership.
CDZ74852.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0693Hypothetical protein.
CDZ74853.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0694Hypothetical protein.
CDZ74854.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0695Hypothetical protein; High confidence in function and specificity.
CDZ74855.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0696Prophage LambdaCh01 protein; Packaging of double-stranded viral DNA concatemers requires interaction of the prohead with virus DNA. This process is mediated by a phage-encoded DNA recognition and [...]
CDZ74856.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0697Phage terminase large subunit; Initiation of packaging of double-stranded viral DNA involves the specific interaction of the prohead with viral DNA in a process mediated by a phage-encoded termin [...]
CDZ74857.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0698Phage portal protein, SPP1 family; This protein forms a hole, or portal, that enables DNA passage during packaging and ejection. It also forms the junction between the phage head (capsid) and the [...]
CDZ74858.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0699Phage putative head morphogenesis protein; This model describes a region of about 110 amino acids found exclusively in phage-related proteins, internally or toward the C-terminus. One member, gp7 [...]
CDZ74859.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0700Hypothetical protein.
CDZ74860.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0701Hypothetical protein; Family membership.
CDZ74861.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0702Hypothetical protein; High confidence in function and specificity.
CDZ74862.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0703Hypothetical protein; Family membership.
CDZ74863.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0704Hypothetical protein.
CDZ74864.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0705Hypothetical protein; High confidence in function and specificity.
CDZ74865.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0706Hypothetical protein.
CDZ74866.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0707Conserved domain protein; High confidence in function and specificity.
CDZ74867.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0708Hypothetical protein; High confidence in function and specificity.
CDZ74868.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0709Conserved domain protein; High confidence in function and specificity.
CDZ74869.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0710Hypothetical protein.
CDZ74870.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0711Members of this family are found in putative phage tail tape measure proteins; High confidence in function and specificity.
CDZ74871.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0712Hypothetical protein; High confidence in function and specificity.
CDZ74872.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0713Hypothetical protein.
CDZ74873.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0714Conserved domain protein; High confidence in function and specificity.
CDZ74874.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0715Conserved domain protein; High confidence in function and specificity.
CDZ74875.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0716Hypothetical protein.
CDZ74876.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0717Conserved domain protein; High confidence in function and specificity.
CDZ74877.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0718Baseplate J-like protein; The P2 bacteriophage J protein lies at the edge of the baseplate. This family also includes a number of bacterial homologues, which are thought to have been horizontally [...]
CDZ74878.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0719Hypothetical protein; High confidence in function and specificity.
CDZ74879.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0720Hypothetical protein.
CDZ74880.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0721Hypothetical protein.
CDZ74881.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0722Addiction module antitoxin; Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plas [...]
CDZ74882.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0723Putative protein conserved; Family membership.
CDZ74883.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0724Hypothetical protein; Family membership.
CDZ74884.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0725Hypothetical protein; Family membership.
CDZ74885.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0726Chitin-binding domain of Chi A1-like proteins; Family membership.
CDZ74886.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0727Putative membrane protein.
CDZ74887.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0728N-acetylmuramoyl-L-alanine amidase; High confidence in function and specificity.
CDZ74888.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0729Putative membrane protein; Family membership.
CDZ74889.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0730Hypothetical protein; High confidence in function and specificity.
CDZ74890.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0731Hypothetical protein.
CDZ74891.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0732Cytotoxic translational repressor of toxin-antitoxin stability system.
CDZ74892.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0733Hypothetical protein.
CDZ74893.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0734Hypothetical protein; Family membership.
CDZ74894.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0735Hypothetical protein; Family membership.
CDZ74895.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0736Hypothetical protein; High confidence in function and specificity.
CDZ74896.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0737Cysteine desulfurase; This domain is found in amino transferases, and other enzymes including cysteine desulphurase; High confidence in function and specificity.
thiI protein networkhttps://string-db.org/network/1912856.ING2D1G_0738Putative tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes [...]
lemA protein networkhttps://string-db.org/network/1912856.ING2D1G_0739LemA family protein; The members of this family are related to the LemA protein P71452. LemA contains an amino terminal predicted transmembrane helix. It has been predicted that the small amino t [...]
CDZ74899.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0740Putative membrane protein; Family membership.
CDZ74900.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0741Helix-turn-helix XRE-family like proteins; High confidence in function and specificity.
potA protein networkhttps://string-db.org/network/1912856.ING2D1G_0742Spermidine/putrescine import ATP-binding protein PotA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport syste [...]
CDZ74902.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0743Spermidine/putrescine transport system permease protein; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; High confidence in function and spec [...]
potC protein networkhttps://string-db.org/network/1912856.ING2D1G_0744Spermidine/putrescine ABC superfamily ATP binding cassette transporter, permease protein; This region seems to be located in a cytoplasmic loop between two transmembrane domains. Apart from the c [...]
potD protein networkhttps://string-db.org/network/1912856.ING2D1G_0745Spermidine/putrescine ABC superfamily ATP binding cassette transporter, binding protein; The bacterial periplasmic spermidine/putrescine-binding proteins are involved in the polyamine transport s [...]
CDZ74905.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0746Hypothetical protein; High confidence in function and specificity.
CDZ74906.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0747HAD hydrolase; The Haloacid Dehydrogenase (HAD) superfamily includes phosphatases, phosphonatases, P-type ATPases, beta-phosphoglucomutases, phosphomannomutases, and dehalogenases, which are invo [...]
rbgA protein networkhttps://string-db.org/network/1912856.ING2D1G_0748Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
rnhB protein networkhttps://string-db.org/network/1912856.ING2D1G_0749Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
CDZ74909.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0750Hypothetical protein; Family membership; Belongs to the UPF0102 family.
CDZ74910.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0751Mg chelatase-like protein; Magnesium-chelatase is a three-component enzyme that catalyses the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio [...]
CDZ74911.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0752The SMF family, of DNA processing chain A, dprA, are a group of bacterial proteins. In H. pylori, dprA is required for natural chromosomal and plasmid transformation [1]. It has now been shown th [...]
CDZ74912.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0753Hypothetical protein; Family membership.
CDZ74913.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0754CBS domains are small intracellular modules that pair together to form a stable globular domain [2]. This family represents a single CBS domain. Pairs of these domains have been termed a Bateman [...]
CDZ74914.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0755FeS assembly ATPase Suf; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex wi [...]
CDZ74915.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0756This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation [...]
CDZ74916.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0757Putative SufB; Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; High confidence in function and specificity.
CDZ74917.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0758Cysteine desulfurase 2, chloroplastic; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
CDZ74918.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0759This domain is found in NifU in combination with PF01106. This domain is found on isolated in several bacterial species such as O53156. The nif genes are responsible for nitrogen fixation. Howeve [...]
CDZ74919.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0760Predicted transcriptional regulator [Transcription]; High confidence in function and specificity.
iscS protein networkhttps://string-db.org/network/1912856.ING2D1G_0761Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental [...]
CDZ74921.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0762Putative membrane protein; High confidence in function and specificity.
alaS protein networkhttps://string-db.org/network/1912856.ING2D1G_0763Alanine-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(A [...]
CDZ74923.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0764Hypothetical protein; Family membership.
CDZ74924.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0765Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
CDZ74925.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0766Hypothetical protein.
CDZ74926.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0767The Ferric uptake regulator (FUR) family includes metal ion uptake regulator proteins. These are responsible for controlling the intracellular concentration of iron in many bacteria. Although iro [...]
rnj protein networkhttps://string-db.org/network/1912856.ING2D1G_0768Ribonucleases; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
CDZ74928.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0769Members of this family are O-methyltransferases. The family includes catechol o-methyltransferase P21964 caffeoyl-CoA O-methyltransferase Q43095 and a family of bacterial O-methyltransferases tha [...]
yrrO protein networkhttps://string-db.org/network/1912856.ING2D1G_0770Peptidase family U32; Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; High confidence in function and specificity.
rny protein networkhttps://string-db.org/network/1912856.ING2D1G_0771Ribonuclease Y; Endoribonuclease that initiates mRNA decay.
xerC protein networkhttps://string-db.org/network/1912856.ING2D1G_0772Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chro [...]
CDZ74932.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0773Putative membrane protein.
lexA protein networkhttps://string-db.org/network/1912856.ING2D1G_0774LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causin [...]
CDZ74934.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0775Putative protein; High confidence in function and specificity.
miaA protein networkhttps://string-db.org/network/1912856.ING2D1G_0776tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(di [...]
mutL-2 protein networkhttps://string-db.org/network/1912856.ING2D1G_0777DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchm [...]
mutS protein networkhttps://string-db.org/network/1912856.ING2D1G_0778DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase act [...]
miaB protein networkhttps://string-db.org/network/1912856.ING2D1G_0779(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenos [...]
CDZ74939.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0780ATPase involved in DNA repair [DNA replication, recombination, and repair]; High confidence in function and specificity.
CDZ74940.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0781Hypothetical protein; Family membership.
CDZ74941.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0782Chromosome segregation protein; High confidence in function and specificity.
CDZ74942.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0783DNA repair exonuclease; High confidence in function and specificity.
recA protein networkhttps://string-db.org/network/1912856.ING2D1G_0784Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of hom [...]
cinA protein networkhttps://string-db.org/network/1912856.ING2D1G_0785Competence is the ability of a cell to take up exogenous DNA from its environment, resulting in transformation. It is widespread among bacteria and is probably an important mechanism for the hori [...]
CDZ74945.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0786CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; All of these members have the ability to catalyse the displacement of CMP from a CDP-alcohol by a second alcohol with formation [...]
rimO protein networkhttps://string-db.org/network/1912856.ING2D1G_0787Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
ftsK protein networkhttps://string-db.org/network/1912856.ING2D1G_0788DNA translocase FtsK; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-termi [...]
dut protein networkhttps://string-db.org/network/1912856.ING2D1G_0789Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intrace [...]
pnp4 protein networkhttps://string-db.org/network/1912856.ING2D1G_0790Polyribonucleotide nucleotidyltransferase 4; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
rpsO protein networkhttps://string-db.org/network/1912856.ING2D1G_079130S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
CDZ74951.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0792Riboflavin biosynthesis protein RibF; This family represents the C-terminal region of the bifunctional riboflavin biosynthesis protein known as RibC in Bacillus subtilis. The RibC protein from Ba [...]
truB protein networkhttps://string-db.org/network/1912856.ING2D1G_0793tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
CDZ74953.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0794Exopolyphosphatase-related proteins [General function prediction only]; High confidence in function and specificity.
rbfA protein networkhttps://string-db.org/network/1912856.ING2D1G_0795Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
infB protein networkhttps://string-db.org/network/1912856.ING2D1G_0796Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
CDZ74956.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0797Hypothetical protein; Family membership.
nusA protein networkhttps://string-db.org/network/1912856.ING2D1G_0798Transcription elongation protein NusA; Participates in both transcription termination and antitermination.
rimP protein networkhttps://string-db.org/network/1912856.ING2D1G_0799Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
CDZ74959.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0800Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; High confidence in function and specificity.
pyrR protein networkhttps://string-db.org/network/1912856.ING2D1G_0801Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the [...]
CDZ74961.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0802Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
lspA protein networkhttps://string-db.org/network/1912856.ING2D1G_0803Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
CDZ74963.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0804Putative protein; High confidence in function and specificity.
sepF protein networkhttps://string-db.org/network/1912856.ING2D1G_0805Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of F [...]
CDZ74965.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0806Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
CDZ74966.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0807Hypothetical protein; High confidence in function and specificity.
gpsA protein networkhttps://string-db.org/network/1912856.ING2D1G_0808Glycerol-3-phosphate dehydrogenase (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate (aka glycerone phosphate, outdated) to sn-glycerol 3-phosphate; [...]
plsY protein networkhttps://string-db.org/network/1912856.ING2D1G_0809Glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utili [...]
der protein networkhttps://string-db.org/network/1912856.ING2D1G_0810GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
CDZ74970.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0811Putative membrane protein; High confidence in function and specificity.
CDZ74971.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0812Putative membrane protein.
CDZ74972.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0813Putative membrane protein; Family membership.
CDZ74973.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0814Putative membrane protein.
CDZ74974.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0815Hypothetical protein; Family membership.
CDZ74975.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0816Putative membrane protein.
CDZ74976.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0817Response regulator of the LytR/AlgR family; Family membership.
nifJ1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0818Pyruvate dehydrogenase (NADP(+)); Pyruvate + CoA + NADP(+) <=> acetyl-CoA + CO(2) + NADPH; High confidence in function and specificity.
hprK protein networkhttps://string-db.org/network/1912856.ING2D1G_0819HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dep [...]
uvrC protein networkhttps://string-db.org/network/1912856.ING2D1G_0820UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible [...]
CDZ74980.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0821Peptidase, M24 family protein; This family contains metallopeptidases. It also contains non-peptidase homologues such as the N terminal domain of Spt16 which is a histone H3-H4 binding module; Hi [...]
spoVG protein networkhttps://string-db.org/network/1912856.ING2D1G_0822Stage V sporulation protein G; Could be involved in septation.
murC protein networkhttps://string-db.org/network/1912856.ING2D1G_0823UDP-N-acetylmuramate-L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
CDZ74983.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0824Hypothetical protein; High confidence in function and specificity.
CDZ74984.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0825Hypothetical protein; High confidence in function and specificity.
CDZ74985.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0826Radical SAM proteins catalyse diverse reactions, including unusual methylations, isomerisation, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation; High confiden [...]
CDZ74986.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0827Peroxiredoxin family; 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH; High confidence in function and specificity.
CDZ74987.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0828Hypothetical protein.
CDZ74988.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0829Aminoacyl-histidine dipeptidase; This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification. Family M20 are Glutamate carboxypeptidases. [...]
msrA protein networkhttps://string-db.org/network/1912856.ING2D1G_0830Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of met [...]
CDZ74990.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0831Hypothetical protein; High confidence in function and specificity.
CDZ74991.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0832PPIC-type PPIASE domain protein; Peptidylprolyl isomerase is an enzyme that accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. [...]
CDZ74992.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0833This domain is known as the 'cold-shock domain' (CSD), part of which is highly; Family membership.
CDZ74993.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0834Acyl-ACP thioesterase; This family consists of various acyl-acyl carrier protein (ACP) thioesterases (TE) these terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid; [...]
glmS protein networkhttps://string-db.org/network/1912856.ING2D1G_0835Glutamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
CDZ74995.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0836Folylpolyglutamate synthase(FPGS) is an ATP-dependent enzyme that is responsible for the addition of a polyglutamate tail to folate and folate derivatives. It plays a key role in the retention of [...]
valS protein networkhttps://string-db.org/network/1912856.ING2D1G_0837Valine-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, i [...]
trpS protein networkhttps://string-db.org/network/1912856.ING2D1G_0838Tryptophan-tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
mtaD protein networkhttps://string-db.org/network/1912856.ING2D1G_0839ATZ_TRZ_like; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate aden [...]
rpsD2 protein networkhttps://string-db.org/network/1912856.ING2D1G_084030S ribosomal protein S4 B; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
CDZ75000.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0841Hypothetical protein; Family membership.
CDZ75001.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0842Pyridoxal-5'-phosphate-dependent protein beta subunit; Pyridoxal phosphate is the active form of vitamin B6 (pyridoxine or pyridoxal). Pyridoxal 5'-phosphate (PLP) is a versatile catalyst, acting [...]
apeA protein networkhttps://string-db.org/network/1912856.ING2D1G_0843Putative M18 family aminopeptidase 1; High confidence in function and specificity.
CDZ75003.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0844TrpR-like protein YerC/YecD; High confidence in function and specificity.
purE protein networkhttps://string-db.org/network/1912856.ING2D1G_0845Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
CDZ75005.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0846Rubrerythrin (Rr), found in anaerobic sulphate-reducing bacteria, is a fusion protein containing an N-terminal diiron-binding domain and a C-terminal domain homologous to rubredoxin. The physiolo [...]
prfA protein networkhttps://string-db.org/network/1912856.ING2D1G_0847Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
hemK protein networkhttps://string-db.org/network/1912856.ING2D1G_0848protein-(glutamine-N5) methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Hig [...]
CDZ75008.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0849Hypothetical protein; High confidence in function and specificity.
rpmE protein networkhttps://string-db.org/network/1912856.ING2D1G_0850Hypothetical protein; Binds the 23S rRNA.
CDZ75010.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0851Putative membrane protein; High confidence in function and specificity.
CDZ75011.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0852Potassium uptake protein KtrA; This domain is often found next to the PF02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. [...]
CDZ75012.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0853Potassium uptake protein KtrB; This family consists of various cation transport proteins (Trk) and V-type sodium ATP synthase subunit J or translocating ATPase J These proteins are involved in ac [...]
rplT protein networkhttps://string-db.org/network/1912856.ING2D1G_0854Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing function [...]
rpmI protein networkhttps://string-db.org/network/1912856.ING2D1G_0855L35 is a basic protein of 60 to 70 amino-acid residues from the large subunit. Like many basic polypeptides, L35 completely inhibits ornithine decarboxylase when present unbound in the cell, but [...]
infC protein networkhttps://string-db.org/network/1912856.ING2D1G_0856Translation initiation factor IF3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhan [...]
polC protein networkhttps://string-db.org/network/1912856.ING2D1G_0857DNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
ispG protein networkhttps://string-db.org/network/1912856.ING2D1G_08584-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG fa [...]
CDZ75018.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0859Zinc metalloprotease; Is responsible for Site-2 cleavage of the RsiW anti-sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and th [...]
CDZ75019.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0860Phosphatidate cytidylyltransferase; The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferaseas well as Sec59 from yea [...]
uppS protein networkhttps://string-db.org/network/1912856.ING2D1G_0861Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
frr protein networkhttps://string-db.org/network/1912856.ING2D1G_0862Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
pyrH protein networkhttps://string-db.org/network/1912856.ING2D1G_0863Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
tsf protein networkhttps://string-db.org/network/1912856.ING2D1G_0864Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
rpsB protein networkhttps://string-db.org/network/1912856.ING2D1G_0865Ribosomal protein S2 is one of the proteins from the small ribosomal subunit. S2 belongs to a family of ribosomal proteins which, on the basis of sequence similarities; High confidence in functio [...]
CDZ75025.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0866Hypothetical protein; High confidence in function and specificity.
CDZ75026.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0867Putative ABC transporter, ATP-binding protein; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporter [...]
fumC protein networkhttps://string-db.org/network/1912856.ING2D1G_0868Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily [...]
engD protein networkhttps://string-db.org/network/1912856.ING2D1G_0869GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
CDZ75029.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0871Hypothetical protein; Family membership.
CDZ75030.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0872Hypothetical protein.
CDZ75031.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0873Putative membrane protein.
CDZ75032.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0874Putative membrane protein.
aspS protein networkhttps://string-db.org/network/1912856.ING2D1G_0875Aspartate-tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end [...]
CDZ75034.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0876Putative UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; High confidence in function and specificity.
CDZ75035.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0877Oxygen-independent coproporphyrinogen III oxidase 2; Members of this radical SAM protein family are HemZ, a protein involved in coproporphyrinogen III decarboxylation. Alternative names for this [...]
CDZ75036.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0878Hydroxyacylglutathione hydrolase; S-(2-hydroxyacyl)glutathione + H(2)O <=> glutathione + a 2-hydroxy carboxylatetransformation in Neisseria gonorrhoeae and could be a transporter involved in DNA [...]
dtd protein networkhttps://string-db.org/network/1912856.ING2D1G_0879D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischar [...]
relA protein networkhttps://string-db.org/network/1912856.ING2D1G_0880GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to chan [...]
CDZ75039.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0881single-stranded-DNA-specific exonuclease RecJ; It is predicted that this family of proteins all perform a phosphoesterase function. It included the single stranded DNA exonuclease RecJ; High conf [...]
CDZ75040.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0882Radical SAM domain protein; Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine; High confidence in function and specificity.
CDZ75041.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0883Hypothetical protein.
CDZ75042.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0884Preprotein translocase subunit YajC [Intracellular trafficking and secretion]; Family membership.
tgt protein networkhttps://string-db.org/network/1912856.ING2D1G_0885Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in [...]
queA protein networkhttps://string-db.org/network/1912856.ING2D1G_0886S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ [...]
CDZ75045.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0887Sporulation protein SpoIID; This model describes a domain found typically in two or three proteins per genome in Cyanobacteria and Firmicutes, and sporadically in other genomes. One member is Spo [...]
ruvB protein networkhttps://string-db.org/network/1912856.ING2D1G_0888Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may [...]
ruvA protein networkhttps://string-db.org/network/1912856.ING2D1G_0889Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may [...]
ruvC protein networkhttps://string-db.org/network/1912856.ING2D1G_0890Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to st [...]
CDZ75049.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0891Hypothetical protein; High confidence in function and specificity.
asnA protein networkhttps://string-db.org/network/1912856.ING2D1G_0892Aspartate-ammonia ligase; ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine; High confidence in function and specificity.
CDZ75051.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0893Hypothetical protein; High confidence in function and specificity.
CDZ75052.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0894Glycosyl hydrolases family 18; High confidence in function and specificity.
rplS protein networkhttps://string-db.org/network/1912856.ING2D1G_0895Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
trmD protein networkhttps://string-db.org/network/1912856.ING2D1G_0896tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rimM protein networkhttps://string-db.org/network/1912856.ING2D1G_089716S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19 [...]
CDZ75056.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0898Hypothetical protein; Family membership; Belongs to the UPF0109 family.
rpsP protein networkhttps://string-db.org/network/1912856.ING2D1G_0899Ribosomal protein S16 is one of the proteins from the small ribosomal subunit; Hypothetical protein; Belongs to the bacterial ribosomal protein bS16 family.
ffh protein networkhttps://string-db.org/network/1912856.ING2D1G_0900Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nasce [...]
CDZ75059.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0901Putative helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulato [...]
CDZ75060.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0902Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
ftsY protein networkhttps://string-db.org/network/1912856.ING2D1G_0903Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the [...]
smc protein networkhttps://string-db.org/network/1912856.ING2D1G_0904Putative SMC family, C-domain protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
CDZ75063.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0905Radical SAM proteins catalyse diverse reactions, including unusual methylations, isomerisation, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation; High confiden [...]
rnc protein networkhttps://string-db.org/network/1912856.ING2D1G_0906Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
acpP protein networkhttps://string-db.org/network/1912856.ING2D1G_0907Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
plsX protein networkhttps://string-db.org/network/1912856.ING2D1G_0908Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but n [...]
CDZ75067.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0909S-layer homology domain protein; High confidence in function and specificity.
CDZ75068.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0910Copper amine oxidases catalyse the oxidative deamination of primary amines to the corresponding aldehydes, while reducing molecular oxygen to hydrogen peroxide. These enzymes are dimers of identi [...]
CDZ75072.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0930Hypothetical protein; High confidence in function and specificity.
CDZ75073.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0931Membrane protein; High confidence in function and specificity.
CDZ75074.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0932Copper amine oxidase N-domain protein; High confidence in function and specificity.
braG protein networkhttps://string-db.org/network/1912856.ING2D1G_0933ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; High confidence in function and specificity.
livG protein networkhttps://string-db.org/network/1912856.ING2D1G_0934Component of the high-affinity branched-chain amino acid transport system; High confidence in function and specificity.
CDZ75077.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0935ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; High confidence in function and specificity; Belongs to the binding-protein-dependen [...]
livH protein networkhttps://string-db.org/network/1912856.ING2D1G_0936Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane; High confidence in functio [...]
CDZ75079.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0937This subgroup includes the type I periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of a [...]
argS protein networkhttps://string-db.org/network/1912856.ING2D1G_0938Arginine-tRNA ligase; ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg); High confidence in function and specificity.
mutS2 protein networkhttps://string-db.org/network/1912856.ING2D1G_0939MutS2 protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mis [...]
CDZ75082.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0940Peptidase, U32 family; This domain is found in a number of proteins belonging to the MEROPS peptidase family U32. Peptidase family U32 contains endopeptidases, including collagenase, from bacteri [...]
CDZ75083.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0941Protein membrane; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the di [...]
pheT protein networkhttps://string-db.org/network/1912856.ING2D1G_0942Phenylalanine-tRNA ligase beta subunit; ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe); High confidence in function and specificity; Belongs to the phenylalanyl- [...]
pheS protein networkhttps://string-db.org/network/1912856.ING2D1G_0943Phenylalanine-tRNA ligase alpha subunit; ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe); High confidence in function and specificity; Belongs to the class-II ami [...]
CDZ75086.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0944Predicted membrane protein [Function unknown]; High confidence in function and specificity.
arcC protein networkhttps://string-db.org/network/1912856.ING2D1G_0945Carbamate kinase is involved in the last step of the AD pathway, converting carbamoyl phosphate and ADP into ammonia, carbon dioxide and ATP; High confidence in function and specificity.
arcB protein networkhttps://string-db.org/network/1912856.ING2D1G_0946Ornithine carbamoyltransferase, catabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline [...]
arcA protein networkhttps://string-db.org/network/1912856.ING2D1G_0947This is a family of arginine deiminases, These enzymes catalyse the conversion of arginine + H2O to citrulline + NH3. The family member from Streptococcus pyogenes has been characterised as an an [...]
CDZ75090.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0948Hypothetical protein; High confidence in function and specificity.
CDZ75091.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0949Major Facilitator Superfamily; Among the different families of transporter, only two occur ubiquitously in all classifications of organisms. These are the ATP-Binding Cassette (ABC) superfamily a [...]
rph protein networkhttps://string-db.org/network/1912856.ING2D1G_0952Ribonuclease PH/Ham1 protein; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can [...]
CDZ75093.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0953N-acetylmuramoyl-L-alanine amidase is an enzyme that catalyzes a chemical reaction that cleaves the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopept [...]
CDZ75094.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0954Hydrogenase maturation factor; This family includes Hydrogen expression/formation protein, HypE, which may be involved in the maturation of NifE hydrogenase; AIR synthase and FGAM synthase, which [...]
CDZ75095.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0955Putative membrane protein.
CDZ75096.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0956Putative type IV prepilin leader peptidase PilD; Peptidase A24, or the prepilin peptidase as it is also known, processes the N-terminus of the prepilins. The processing is essential for the corre [...]
CDZ75097.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0957Putative type IV pilin; This short sequence motif appears a the N-terminus of type IV prokaryotic filamentous adhesins or pilins. The N-terminal residue, which is methylated, is hydrophobic (gene [...]
CDZ75098.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0958Putative bacterial type II secretion system protein F; The original family covered both the regions found by the current model. The splitting of the family has allowed the related FlaJ_arch (arch [...]
CDZ75099.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0959Type II secretory pathway; This family describes GspE, the E protein of the type II secretion system, also called the main terminal branch of the general secretion pathway. This model separates G [...]
topA protein networkhttps://string-db.org/network/1912856.ING2D1G_0960DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of [...]
CDZ75101.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0961Hypothetical protein; High confidence in function and specificity.
CDZ75102.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0962Putative conserved protein; High confidence in function and specificity.
CDZ75103.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0963Putative methyltransferase; High confidence in function and specificity.
sigA protein networkhttps://string-db.org/network/1912856.ING2D1G_0964RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the p [...]
dnaG protein networkhttps://string-db.org/network/1912856.ING2D1G_0965DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
CDZ75106.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0966Deoxyguanosinetriphosphate triphosphohydrolase-like protein; Deoxyguanosine triphosphate triphosphohydrolase (dGTPase) releases inorganic triphosphate, an unusual reaction product, from GTP.dGTPa [...]
CDZ75107.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0967Putative pyruvate, phosphate dikinase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzin [...]
ccpN protein networkhttps://string-db.org/network/1912856.ING2D1G_0968CBS domains are small intracellular modules that pair together to form a stable globular domain. This family represents a single CBS domain. Pairs of these domains have been termed a Bateman doma [...]
glyS protein networkhttps://string-db.org/network/1912856.ING2D1G_0969This entry represents the beta subunit of the tetrameric enzyme. What is most interesting is the lack of similarity between the two types: divergence at the sequence level is so great that it is [...]
glyQ protein networkhttps://string-db.org/network/1912856.ING2D1G_0970Glycine-tRNA ligase alpha subunit; ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly); High confidence in function and specificity.
recO protein networkhttps://string-db.org/network/1912856.ING2D1G_0971DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
era protein networkhttps://string-db.org/network/1912856.ING2D1G_0972GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cyc [...]
cdd protein networkhttps://string-db.org/network/1912856.ING2D1G_0973Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
CDZ75114.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0974Diacylglycerol kinase (DGK or DAGK) is a family of enzymes that catalyzes the conversion of diacylglycerol (DAG) to phosphatidic acid (PA) utilizing ATP as a source of the phosphate. In non-stimu [...]
ybeY protein networkhttps://string-db.org/network/1912856.ING2D1G_0975Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
phoH protein networkhttps://string-db.org/network/1912856.ING2D1G_0976PhoH is a cytoplasmic protein and predicted ATPase that is induced by phosphate starvation; High confidence in function and specificity.
CDZ75117.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0977Hypothetical protein; Family membership.
CDZ75118.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0978UPF0365 protein; High confidence in function and specificity.
CDZ75119.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0979Nodulation efficiency protein D (NfeD); NfeD-like proteins are widely distributed throughout prokaryotes and are frequently associated with genes encoding stomatin-like proteins (slipins). There [...]
CDZ75120.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0980GatB/Yqey domain protein; The function of this domain found in the YqeY protein is uncertain; High confidence in function and specificity.
rpsU protein networkhttps://string-db.org/network/1912856.ING2D1G_0981Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
hinT protein networkhttps://string-db.org/network/1912856.ING2D1G_0982Purine nucleoside phosphoramidase; HIT (histidine triad) proteins, named for a short motif related to the sequence (His-x-His-x-His-x-x, where x is a hydrophobic residue) [1,2] are a superfamily [...]
mtaB protein networkhttps://string-db.org/network/1912856.ING2D1G_0983Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB; Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t6A), leading to the formation of 2-methylthio-N6-threonylcarbamoylade [...]
CDZ75124.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0984RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
prmA protein networkhttps://string-db.org/network/1912856.ING2D1G_0985Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
dnaJ protein networkhttps://string-db.org/network/1912856.ING2D1G_0986Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an [...]
dnaK protein networkhttps://string-db.org/network/1912856.ING2D1G_0987Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
grpE protein networkhttps://string-db.org/network/1912856.ING2D1G_0988Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nu [...]
hrcA protein networkhttps://string-db.org/network/1912856.ING2D1G_0989Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
iadA protein networkhttps://string-db.org/network/1912856.ING2D1G_0990Beta-aspartyl peptidase; Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation. Belong [...]
CDZ75131.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0991Hypothetical protein membrane; High confidence in function and specificity.
spsB protein networkhttps://string-db.org/network/1912856.ING2D1G_0992Signal peptidase IB; Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins; High confidence in function and specificity; Belongs to the peptidase S [...]
lepA protein networkhttps://string-db.org/network/1912856.ING2D1G_0993Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon bac [...]
CDZ75134.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_0994Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalentl [...]
rpsT protein networkhttps://string-db.org/network/1912856.ING2D1G_099530S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
CDZ75136.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_0996DNA polymerase III, delta subunit is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalysed reacti [...]
CDZ75137.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0997DNA internalization-related competence protein ComEC/Rec2; Apparant orthologs are found in 5 species so far (Haemophilus influenzae, Escherichia coli, Bacillus subtilis, Neisseria gonorrhoeae, St [...]
cadA protein networkhttps://string-db.org/network/1912856.ING2D1G_0998Cadmium, zinc and cobalt-transporting ATPase; High confidence in function and specificity.
CDZ75139.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_0999Hypothetical protein; High confidence in function and specificity.
pgpB protein networkhttps://string-db.org/network/1912856.ING2D1G_1000Membrane-associated phospholipid phosphatase; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase, Phosphatidylglycerophosphatase Band bacterial aci [...]
CDZ75141.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1001DNA helicase II; The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyse ATP dependent unwinding of double stranded DNA to sing [...]
CDZ75142.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1002Magnesium transporter; Acts as a magnesium transporter.
CDZ75143.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1003This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins; Family membership.
sfsA protein networkhttps://string-db.org/network/1912856.ING2D1G_1004This family contains Sugar fermentation stimulation proteins. Which is probably a regulatory factor involved in maltose metabolism. SfsA has been shown to bind DNA [2] and it contains a helix-tur [...]
rpsI protein networkhttps://string-db.org/network/1912856.ING2D1G_1005Ribosomal protein S9 is one of the proteins from the small ribosomal subunit. It belongs to the S9P family of ribosomal proteins which, on the basis of sequence similarities,groups bacterial; alg [...]
rplM protein networkhttps://string-db.org/network/1912856.ING2D1G_100650S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
etfA1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1007An electron transfer flavoprotein (ETF) is a flavoprotein and functions as a specific electron acceptor for primary dehydrogenases, transferring the electrons to terminal respiratory systems such [...]
etfB1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1008An electron transfer flavoprotein (ETF) is a flavoprotein and functions as a specific electron acceptor for primary dehydrogenases, transferring the electrons to terminal respiratory systems such [...]
bcd1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1009Acyl-CoA dehydrogenase, short-chain specific; Butanoyl-CoA + electron-transfer flavoprotein = 2-butenoyl-CoA + reduced electron-transfer flavoprotein; High confidence in function and specificity.
ilvD1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1010Dihydroxy-acid dehydratase catalyses the fourth step in the biosynthesis of isoleucine and valine, the dehydratation of 2,3-dihydroxy-isovaleic acid into alpha-ketoisovaleric acid. 6-Phosphogluco [...]
yloB protein networkhttps://string-db.org/network/1912856.ING2D1G_1011Calcium-transporting ATPase; High confidence in function and specificity.
CDZ75152.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1012Hypothetical protein; High confidence in function and specificity.
CDZ75153.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1013Nitrogen regulatory protein P-II; P-II modulates the activity of glutamine synthetase; High confidence in function and specificity.
CDZ75154.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1014Hypothetical protein; High confidence in function and specificity.
truA protein networkhttps://string-db.org/network/1912856.ING2D1G_1015tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
ecfT protein networkhttps://string-db.org/network/1912856.ING2D1G_1016Energy-coupling factor transporter transmembrane protein EcfT; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF tra [...]
ecfA1-1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1017Energy-coupling factor transporter ATP-binding protein EcfA 1; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF [...]
ecfA1-2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1018Energy-coupling factor transporter ATP-binding protein EcfA 1; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF [...]
pyrE protein networkhttps://string-db.org/network/1912856.ING2D1G_1019Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
pyrF protein networkhttps://string-db.org/network/1912856.ING2D1G_1020Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamil [...]
CDZ75161.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1021Hypothetical protein; Family membership; Belongs to the UPF0145 family.
prfB protein networkhttps://string-db.org/network/1912856.ING2D1G_1022Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
yacL protein networkhttps://string-db.org/network/1912856.ING2D1G_1023Putative PIN and TRAM-domain containing protein YacL; High confidence in function and specificity.
CDZ75164.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1024Transcriptional regulator, CarD family; CarD is a Myxococcus xanthus protein required for the activation of light-and starvation-inducible genes. This family includes the presumed N-terminal doma [...]
CDZ75165.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1025Na+-driven multidrug efflux pump; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range o [...]
ftnB protein networkhttps://string-db.org/network/1912856.ING2D1G_1026Nonheme iron-containing ferritin; Iron-storage protein.
CDZ75167.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1027Hypothetical protein.
CDZ75168.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1028Hypothetical protein; High confidence in function and specificity.
yaaT protein networkhttps://string-db.org/network/1912856.ING2D1G_1029Stage 0 sporulation protein YaaT; High confidence in function and specificity.
CDZ75170.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1030DNA polymerase III, gamma/tau subunits [DNA replication, recombination, and repair]; High confidence in function and specificity.
CDZ75171.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1031Putative protein conserved in bacteria; Family membership.
CDZ75172.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1032Hypothetical protein; High confidence in function and specificity.
tmk protein networkhttps://string-db.org/network/1912856.ING2D1G_1033Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
CDZ75174.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1034In molecular biology, group III pyridoxal-dependent decarboxylases are a family of bacterial enzymes comprising ornithine decarboxylase, lysine decarboxylaseand arginine decarboxylase; High confi [...]
CDZ75175.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1035Hypothetical protein; Family membership.
citF protein networkhttps://string-db.org/network/1912856.ING2D1G_1036In citrate-utilising prokaryotes, citrate lyasecleaves intracellular citrate into acetate and oxaloacetate, and is organised as a functional complex consisting of alpha, beta, and gamma subunits. [...]
citE protein networkhttps://string-db.org/network/1912856.ING2D1G_1037In citrate-utilising prokaryotes, citrate lyasecleaves intracellular citrate into acetate and oxaloacetate, and is organised as a functional complex consisting of alpha, beta, and gamma subunits. [...]
CDZ75178.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1038Citrate lyase, gamma subunit [Energy production and conversion]; Family membership.
CDZ75179.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1039Membrane protein; Family membership.
CDZ75180.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1040TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; High confidence in function and specificity.
CDZ75181.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1041Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible fo [...]
CDZ75182.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1042LysR substrate binding domain; The structure of this domain is known and is; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
nnrE protein networkhttps://string-db.org/network/1912856.ING2D1G_1043Hypothetical protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite fo [...]
CDZ75184.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1044MUG-like Uracil-DNA glycosylase enzyme family; G:T/U mismatch-specific DNA glycosylase [DNA replication, recombination, and repair]; High confidence in function and specificity.
CDZ75185.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1045ABC-type uncharacterized transport system; High confidence in function and specificity.
CDZ75186.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1046This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH P08340 and LivM P22729 both of which are form the LIV-I transport system [...]
CDZ75187.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1047This family contains many hypothetical proteins and some ABC transporter substrate binding proteins; High confidence in function and specificity.
CDZ75188.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1048Flavin reductase; Multimeric flavodoxin WrbA [General function prediction only]; High confidence in function and specificity.
CDZ75189.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1049NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; High confidence in function and specificity.
CDZ75190.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1050Pirin-related protein; Pirin is composed of two structurally similar domains arranged face to face. Although the two domains are similar, the C-terminal domain of Pirin differs from the N-termina [...]
pyrP protein networkhttps://string-db.org/network/1912856.ING2D1G_1051Uracil permease; Proteins in this family are uracil transporters. The Escherichia coli uracil/H(+) symporter UraA is the representative member. UraA has a structural fold consisting of 14 transme [...]
CDZ75192.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1052TRAP-type uncharacterized transport system; High confidence in function and specificity.
CDZ75193.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1053Hypothetical protein; Family membership.
CDZ75194.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1054TRAP-type uncharacterized transport system; High confidence in function and specificity.
CDZ75195.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1055Hypothetical protein; High confidence in function and specificity; Belongs to the CoA-transferase III family.
CDZ75196.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1056Methylmalonyl-CoA carboxyltransferase 12S subunit; High confidence in function and specificity.
CDZ75197.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1057Hypothetical protein; The structure of this domain is known and is; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
CDZ75198.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1058Hydantoin racemase; This family contains aspartate racemase, maleate isomerases, glutamate racemase, hydantoin racemase and arylmalonate decarboxylase; Family membership.
CDZ75199.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1059Amidase, hydantoinase/carbamoylase family; Hydantoinase and carbamoylasehydrolyse the amide bonds of compounds containing carbamoyl groups or hydantoin rings.Enzymes in this subfamily are key bio [...]
CDZ75200.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1060Amidohydrolase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; High confidence in function and specificity.
CDZ75201.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1061Na+/proline symporter; Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro-and eukaryotic cells. Thereby the energy stored [...]
CDZ75202.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1062Putative membrane protein.
CDZ75203.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1063Putative membrane protein.
CDZ75204.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1064Hypothetical protein; The structure of this domain is known and is; Family membership; Belongs to the LysR transcriptional regulatory family.
CDZ75205.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1065Putative membrane protein.
CDZ75206.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1066Metal cation transporter, ZIP family; The ZIP family consists of zinc transport proteins and many putative metal transporters. The main contribution to this family is from the Arabidopsis thalian [...]
ftsH2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1067ATP-dependent zinc metalloprotease FtsH 2; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral me [...]
CDZ75208.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1068IMP + diphosphate <=> hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate; High confidence in function and specificity; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
tilS protein networkhttps://string-db.org/network/1912856.ING2D1G_1069tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidinesynthetase); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP- [...]
CDZ75210.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1070Hypothetical protein; High confidence in function and specificity.
CDZ75211.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1071Septum formation initiator; Family membership.
CDZ75212.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1072Hypothetical protein.
hup protein networkhttps://string-db.org/network/1912856.ING2D1G_1073DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
CDZ75214.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1074Hypothetical protein.
CDZ75215.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1075Putative tetrapyrrole methylase family protein/MazG family protein; Tetrapyrroles are large macrocyclic compounds derived from a common biosynthetic pathway. The end-product, uroporphyrinogen III [...]
CDZ75216.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1076Peptidyl-prolyl cis-trans isomerase; Peptidylprolyl isomerase is an enzyme that accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopepti [...]
mfd protein networkhttps://string-db.org/network/1912856.ING2D1G_1077Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated tr [...]
pth protein networkhttps://string-db.org/network/1912856.ING2D1G_1078Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
prs protein networkhttps://string-db.org/network/1912856.ING2D1G_1079Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
glmU protein networkhttps://string-db.org/network/1912856.ING2D1G_1080Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer [...]
CDZ75221.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1081Hypothetical protein; Family membership.
CDZ75222.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1082Phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related protein [...]
phoB protein networkhttps://string-db.org/network/1912856.ING2D1G_1083Phosphate regulon response regulator; Two-component signal transduction systems enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; Hig [...]
phoU protein networkhttps://string-db.org/network/1912856.ING2D1G_1084Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.
pstB3 protein networkhttps://string-db.org/network/1912856.ING2D1G_1085Phosphate import ATP-binding protein PstB 3; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC [...]
pstA protein networkhttps://string-db.org/network/1912856.ING2D1G_1086Phosphate ABC superfamily ATP binding cassette transporter, membrane protein; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop [...]
pstC protein networkhttps://string-db.org/network/1912856.ING2D1G_1087Phosphate ABC superfamily ATP binding cassette transporter, permease protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of t [...]
CDZ75228.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1088ABC-type phosphate transport system periplasmic component-like protein; This domain belongs to the periplasmic binding protein superfamily; High confidence in function and specificity.
CDZ75229.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1089Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transc [...]
CDZ75230.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1090NAD/nadp octopine/nopaline dehydrogenase; The octopine dehydrogenase family of enzymes act on the CH-NH substrate bond using NAD(+) or NADP(+) as an acceptor. The family includes octopine dehydro [...]
CDZ75231.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1091The anaerobic C4-dicarboxylate membrane transporter protein family (or C4-dicarboxylate Uptake (Dcu) family) is a family of proteins which includes the DcuA, DcuB and DcuC proteins. Many members [...]
rplQ protein networkhttps://string-db.org/network/1912856.ING2D1G_1092Ribosomal protein L17 is one of the proteins from the large ribosomal subunit. Bacterial L17 is a protein of 120 to 130 amino-acid residues while yeast YmL8 is twice as large (238 residues). The [...]
rpoA protein networkhttps://string-db.org/network/1912856.ING2D1G_1093DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpsK protein networkhttps://string-db.org/network/1912856.ING2D1G_109430S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsM protein networkhttps://string-db.org/network/1912856.ING2D1G_109530S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpmJ protein networkhttps://string-db.org/network/1912856.ING2D1G_1096Ribosomal protein L36 is the smallest protein from the large subunit of the prokaryotic ribosome. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities can be [...]
infA protein networkhttps://string-db.org/network/1912856.ING2D1G_1097Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
CDZ75238.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1098Hypothetical protein.
adk protein networkhttps://string-db.org/network/1912856.ING2D1G_1099Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
secY protein networkhttps://string-db.org/network/1912856.ING2D1G_1100Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at [...]
rplO protein networkhttps://string-db.org/network/1912856.ING2D1G_110150S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
rpmD protein networkhttps://string-db.org/network/1912856.ING2D1G_1102Ribosomal protein L30 is one of the proteins from the large ribosomal subunit. L30 belongs to a family of ribosomal proteins which, on the basis of sequence similarities, groups bacteria and arch [...]
rpsE protein networkhttps://string-db.org/network/1912856.ING2D1G_110330S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 fam [...]
rplR protein networkhttps://string-db.org/network/1912856.ING2D1G_1104Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
rplF protein networkhttps://string-db.org/network/1912856.ING2D1G_110550S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rpsH protein networkhttps://string-db.org/network/1912856.ING2D1G_110630S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to [...]
rpsZ protein networkhttps://string-db.org/network/1912856.ING2D1G_1107Hypothetical protein; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
rplE protein networkhttps://string-db.org/network/1912856.ING2D1G_110850S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rplX protein networkhttps://string-db.org/network/1912856.ING2D1G_1109Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplN protein networkhttps://string-db.org/network/1912856.ING2D1G_111050S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rpsQ protein networkhttps://string-db.org/network/1912856.ING2D1G_1111Hypothetical protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rpmC protein networkhttps://string-db.org/network/1912856.ING2D1G_1112Ribosomal protein L29 is one of the proteins from the large ribosomal subunit. L29 belongs to a family of ribosomal proteins of 63 to 138 amino-acid residues which; Family membership.
rplP protein networkhttps://string-db.org/network/1912856.ING2D1G_111350S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsC protein networkhttps://string-db.org/network/1912856.ING2D1G_111430S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplV protein networkhttps://string-db.org/network/1912856.ING2D1G_111550S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wal [...]
rpsS protein networkhttps://string-db.org/network/1912856.ING2D1G_1116Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplB protein networkhttps://string-db.org/network/1912856.ING2D1G_111750S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rplW protein networkhttps://string-db.org/network/1912856.ING2D1G_111850S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplD protein networkhttps://string-db.org/network/1912856.ING2D1G_111950S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
rplC protein networkhttps://string-db.org/network/1912856.ING2D1G_112050S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal rib [...]
rpsJ protein networkhttps://string-db.org/network/1912856.ING2D1G_1121Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
CDZ75262.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1122Thioredoxin; Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, [...]
CDZ75263.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1123Putative protein; Family membership.
CDZ75264.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1124Hypothetical protein; Family membership.
CDZ75265.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1125DNA-binding transcriptional regulator, PadR family; Family membership.
CDZ75266.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1126Members of this family are all pyridoxal-phosphate dependent enzymes. This family includes: serine dehydrataseP20132, threonine dehydrataseP04968 tryptophan synthase beta chainthreonine synthasec [...]
CDZ75267.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1127Na+/alanine symporter; These transporters are believed to possess 8 transmembrane (TM) helices, forming a channel or pore through the cytoplasmic membrane, the interior face being hydrophilic to [...]
glsA protein networkhttps://string-db.org/network/1912856.ING2D1G_1128Glutaminases deaminate glutamine to glutamate. In Bacillus subtilis, glutaminase is encoded by glnA, which is part of an operon, glnA-glnT (formerly ybgJ-ybgH), where glnT encodes a glutamine tra [...]
CDZ75269.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1129TrmH family RNA methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltrans [...]
CDZ75270.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1130Putative secreted protein.
bdhA protein networkhttps://string-db.org/network/1912856.ING2D1G_1131Alcohol dehydrogenases (ADH) are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of n [...]
gcp protein networkhttps://string-db.org/network/1912856.ING2D1G_1132Putative tRNA threonylcarbamoyladenosine biosynthesis protein Gcp; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginnin [...]
CDZ75273.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1133Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negativ [...]
CDZ75274.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1134O-sialoglycoprotein endopeptidase; This domain was identified in proteins including Kae1 and Gcp (YgjD), which were originally thought to be endopeptidases belonging to the peptidase M22 family. [...]
CDZ75275.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1135tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE [Translation, ribosomal structure and biogenesis]; High confidence in function and specificity.
CDZ75276.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1136The nitroreductase family comprises a group of FMN-or FAD-dependent and NAD(P)H-dependent enzymes able to metabolize nitrosubstituted compounds; High confidence in function and specificity.
CDZ75277.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1137Family of uncharacterized bacterial proteins; Family membership.
CDZ75278.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1138Hypothetical protein; High confidence in function and specificity.
CDZ75279.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1139Putative Aconitase X catalytic domain. It is predicted by comparative genomic analysis. The proteins are mainly found in archaea and proteobacteria. They are distantly related to Aconitase family [...]
CDZ75280.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1140Putative Aconitase; Family membership.
CDZ75281.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1141This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase. It [...]
lysA protein networkhttps://string-db.org/network/1912856.ING2D1G_1142Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
CDZ75283.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1143Endoribonuclease L-PSP; High confidence in function and specificity.
CDZ75284.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1144Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes, such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the ba [...]
CDZ75285.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1145Putative membrane protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
CDZ75286.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1146NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity [...]
CDZ75287.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1147ArsR family transcriptional regulator; Family membership.
rsmA protein networkhttps://string-db.org/network/1912856.ING2D1G_1148Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S part [...]
rnmV protein networkhttps://string-db.org/network/1912856.ING2D1G_1149Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
CDZ75290.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1150TatD like proteins; This family of proteins are related to a large superfamily of metalloenzymes. TatD, a member of this family has been shown experimentally to be a DNase enzyme; High confidence [...]
metG protein networkhttps://string-db.org/network/1912856.ING2D1G_1151Methionine-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
CDZ75292.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1152Universal stress protein UspA; Transcriptional induction of the uspA gene of Escherichia coli occurs when conditions cause growth arrest; cells deficient in UspA survive poorly in stationary phas [...]
nrdG protein networkhttps://string-db.org/network/1912856.ING2D1G_1153Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radic [...]
nrdD protein networkhttps://string-db.org/network/1912856.ING2D1G_1154This entry is found in the oxygen-sensitive (anaerobic, class III) ribonucleotide reductase. The mechanism of the enzyme involves a glycine-centred radical a C-terminal zinc binding site, and a s [...]
CDZ75295.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1155Hypothetical protein; High confidence in function and specificity.
rpoC protein networkhttps://string-db.org/network/1912856.ING2D1G_1156DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/1912856.ING2D1G_1157DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
CDZ75298.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1158Hypothetical protein; Family membership.
CDZ75299.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1159Alpha/beta hydrolase family; High confidence in function and specificity.
CDZ75300.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1160Hypothetical protein; High confidence in function and specificity.
hutH protein networkhttps://string-db.org/network/1912856.ING2D1G_1161Histidine ammonia-lyase deaminates histidine to urocanic acid, the first step in histidine degradation. It is closely related to the plant enzyme phenylalanine ammonia-lyase but is absent in plan [...]
CDZ75302.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1162Putative histidine transporter YuiF; High confidence in function and specificity.
CDZ75303.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1163Predicted ATPase [General function prediction only]; High confidence in function and specificity.
CDZ75304.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1164Putative proton-coupled thiamine transporter YuaJ; Members of this protein family have been assigned as thiamine transporters by a phylogenetic analysis of families of genes regulated by the THI [...]
CDZ75305.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1165Hypothetical protein; Family membership.
pta protein networkhttps://string-db.org/network/1912856.ING2D1G_1166This entry contains both phosphate acetyltransferase: Acetyl-CoA + phosphate = CoA + acetyl phosphate and phosphate butaryltransferase:, Butanoyl-CoA + phosphate = CoA + butanoyl phosphate, These [...]
CDZ75307.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1167Metallo-beta-lactamase domain protein; Apart from the beta-lactamases and metallo-beta-lactamases, a number of other proteins contain this domain. These proteins include thiolesterases, members o [...]
CDZ75308.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1168Hypothetical protein; Family membership.
CDZ75309.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1169Protein-tyrosine-phosphatase [Signal transduction mechanisms]; High confidence in function and specificity; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
CDZ75310.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1170Thioredoxin domain; Family membership.
CDZ75311.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1171Permease family protein; A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the pref [...]
CDZ75312.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1172ArsR family transcriptional regulator; Members of this family contains a DNA binding 'helix-turn-helix' motif. This family includes other proteins which are not included in the Prosite definition [...]
gatB protein networkhttps://string-db.org/network/1912856.ING2D1G_1173Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu [...]
gatA protein networkhttps://string-db.org/network/1912856.ING2D1G_1174Glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-t [...]
CDZ75315.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1175Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gl [...]
ligA protein networkhttps://string-db.org/network/1912856.ING2D1G_1176DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sourc [...]
pcrA protein networkhttps://string-db.org/network/1912856.ING2D1G_1177This entry reprsents ATP-dependent DNA helicase PcrA in bacteria, wich belongs to the UvrD/Rep helicase family. It has a broad nucleotide specificity, even being able to hydrolyze ethenonucleotid [...]
CDZ75318.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1178tRNA A37 threonylcarbamoyladenosine dehydratase [Translation, ribosomal structure and biogenesis]; High confidence in function and specificity.
CDZ75319.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1179Putative S-layer homology domain protein; High confidence in function and specificity.
CDZ75320.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1180Acyl-coenzyme A thioesterase PaaI, contains HGG motif [Secondary metabolites biosynthesis, transport and catabolism]; Family membership.
CDZ75321.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1181Phosphohistidine phosphatase (SixA); The histidine phosphatase superfamily is so named because catalysis centres on a conserved His residue that is transiently phosphorylated during the catalytic [...]
eno protein networkhttps://string-db.org/network/1912856.ING2D1G_1182Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
gpmI protein networkhttps://string-db.org/network/1912856.ING2D1G_1183Phosphoglycerate mutase (2,3-diphosphoglycerate-independent); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
tpiA protein networkhttps://string-db.org/network/1912856.ING2D1G_1184Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to th [...]
pgk protein networkhttps://string-db.org/network/1912856.ING2D1G_1185Phosphoglycerate kinase is an enzyme that catalyses the formation of ATP to ADP and vice versa. In the second step of the second phase in glycolysis, 1,3-diphosphoglycerate is converted to 3-phos [...]
gapB protein networkhttps://string-db.org/network/1912856.ING2D1G_1186Glyceraldehyde-3-phosphate dehydrogenase 2; D-glyceraldehyde 3-phosphate + phosphate + NAD(P)(+) <=> 3-phospho-D-glyceroyl phosphate + NAD(P)H; High confidence in function and specificity; Belong [...]
CDZ75327.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1187Putative central glycolytic genes regulator; This probable domain is found in bacterial transcriptional regulators such as DeoR, SorC and CggR. One of these proteins, Q8U7I7, has an N-terminal he [...]
gltX protein networkhttps://string-db.org/network/1912856.ING2D1G_1188Glutamate-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of [...]
CDZ75329.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1189Membrane protein; High confidence in function and specificity.
CDZ75330.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1190Putative membrane protein.
CDZ75331.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1191Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) [...]
CDZ75332.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1192Ferrous iron transport protein A; The C-terminal domain of several bacterial transcriptional repressors show structural homology to one another. These domains are characterised by an SH3-like str [...]
CDZ75333.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1193FeoA domain; This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcripti [...]
birA protein networkhttps://string-db.org/network/1912856.ING2D1G_1195biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
pgi protein networkhttps://string-db.org/network/1912856.ING2D1G_1196Glucose-6-phosphate isomerase (alternatively known as phosphoglucose isomerase or phosphohexose isomerase) is an enzyme that catalyzes the conversion of glucose-6-phosphate into fructose 6-phosph [...]
CDZ75336.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1197Serine phosphatase RsbU; High confidence in function and specificity.
ypsC protein networkhttps://string-db.org/network/1912856.ING2D1G_1198Putative RNA methyltransferase YpsC; In prokaryotes, the major role of DNA methylation is to protect host DNA against degradation by restriction enzymes. There are 2 major classes of DNA methyltr [...]
CDZ75338.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1199ABC superfamily ATP binding cassette transporter; High confidence in function and specificity.
yknY protein networkhttps://string-db.org/network/1912856.ING2D1G_1200Putative ABC transporter ATP-binding protein; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division ( [...]
CDZ75340.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1201Putative efflux transporter, RND family, MFP subunit; High confidence in function and specificity.
CDZ75341.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1202Putative membrane protein; High confidence in function and specificity.
CDZ75342.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1203Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix [...]
nifJ3 protein networkhttps://string-db.org/network/1912856.ING2D1G_1204Pyruvate-flavodoxin oxidoreductase; The oxidative decarboxylation of pyruvate to acetyl-CoA, a central step in energy metabolism, can occur by two different mechanisms. In anaerobic organisms, th [...]
CDZ75344.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1205L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
CDZ75345.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1206TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; High confidence in function and specificity.
CDZ75346.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1207Hypothetical protein; Family membership.
CDZ75347.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1208PBP2_TRAP_Siap_TeaA_like; This subfamily includes the periplasmic-binding component of TRAP transport systems such as SiaP (a sialic acid binding virulence factor), TeaA (an ectoine binding prote [...]
CDZ75348.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1209Hypothetical protein; Family membership.
abfD protein networkhttps://string-db.org/network/1912856.ING2D1G_1210Catalyzes the reversible conversion of 4-hydroxybutyryl-CoA to crotonyl-CoA. The mechanism of the reaction seems to go through three steps: (1) the FAD-dependent oxidation of 4-hydroxybutyryl-CoA [...]
CDZ75350.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1211This family of bacterial transcriptional regulators includes the glycerol operon regulatory protein and acetate operon repressor both of which are members of the iclR family. These proteins have [...]
ilvE protein networkhttps://string-db.org/network/1912856.ING2D1G_1212Putative branched-chain-amino-acid aminotransferase; L-leucine + 2-oxoglutarate <=> 4-methyl-2-oxopentanoate + L-glutamate, L-isoleucine + 2-oxoglutarate <=> (S)-3-methyl-2-oxopentanoate + L-glut [...]
ilvA protein networkhttps://string-db.org/network/1912856.ING2D1G_1213Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a produc [...]
ilvD3 protein networkhttps://string-db.org/network/1912856.ING2D1G_1214Two dehydratases, dihydroxy-acid dehydratase (gene ilvD or ILV3) and 6-phosphogluconate dehydratase (gene edd) have been shown to be evolutionary related. Dihydroxy-acid dehydratase catalyzes the [...]
ilvC protein networkhttps://string-db.org/network/1912856.ING2D1G_1215Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
ilvH protein networkhttps://string-db.org/network/1912856.ING2D1G_1216Acetolactate synthases are a group of biosynthetic enzymes apparently found in plants, fungi and bacteria that are capable of de novo synthesis of the branched-chain amino acids. They can all syn [...]
ilvI protein networkhttps://string-db.org/network/1912856.ING2D1G_1217Acetolactate synthase large subunit; 2 pyruvate = 2-acetolactate + CO2; High confidence in function and specificity.
CDZ75357.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1218ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily, which uses the hydrolysis of ATP to energise diverse biological systems. ABC transporters minimally consist of two conserved [...]
sorA protein networkhttps://string-db.org/network/1912856.ING2D1G_1219Superoxide reductase; Desulfoferrodoxins contains two types of iron: an Fe-S4 site very; High confidence in function and specificity.
CDZ75359.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1220S-layer homology domain; High confidence in function and specificity.
CDZ75360.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1221Putative permease MJ0326; This family includes permeases for diverse substrates such as xanthine P42086 uracil P39766 and vitamin C Q9UGH3. However many members of this family are functionally un [...]
CDZ75361.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1222Peptidase family protein; High confidence in function and specificity.
CDZ75362.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1223Putative uncharacterized protein; Family membership.
CDZ75363.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1224polyphosphate:AMP phosphotransferase; Members of this protein family contain a domain duplication. The characterized member from Acinetobacter johnsonii is polyphosphate:AMP phosphotransferase (P [...]
CDZ75364.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1225YbaK/prolyl-tRNA synthetase associated regio; Family membership.
clsA protein networkhttps://string-db.org/network/1912856.ING2D1G_1226Major cardiolipin synthase ClsA; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glyce [...]
typA protein networkhttps://string-db.org/network/1912856.ING2D1G_1227GTP-binding protein TypA/BipA homolog; High confidence in function and specificity.
CDZ75367.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1228Hypothetical protein; High confidence in function and specificity.
ung protein networkhttps://string-db.org/network/1912856.ING2D1G_1229Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
CDZ75369.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1230Putative potassium uptake protein TrkA; The Trk system is a low to medium affinity potassium uptake system, widely found in both in bacteria and archaea, where the uptake of K(+) is believed to b [...]
CDZ75370.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1231Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA and requires TrkE for transport activity. Selective for permeation of potassium ion and rubidium i [...]
CDZ75371.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1232Potassium uptake protein TrkA; High confidence in function and specificity.
CDZ75372.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1233Cobalt-zinc-cadmium resistance protein CzcD; Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. [...]
CDZ75373.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1234Hypothetical protein; Family membership.
CDZ75374.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1235Putative secreted protein.
CDZ75375.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1236Hypothetical protein; High confidence in function and specificity.
CDZ75376.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1237Putative 4Fe-4S ferredoxin, iron-sulfur binding protein; Ferredoxins are a group of iron-sulphur proteins which mediate electron transfer in a wide variety of metabolic reactions. Ferredoxins can [...]
CDZ75377.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1238Hypothetical protein.
CDZ75378.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1239Hypothetical protein; High confidence in function and specificity.
pyc protein networkhttps://string-db.org/network/1912856.ING2D1G_1240Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate [...]
rbr protein networkhttps://string-db.org/network/1912856.ING2D1G_1242Rubrerythrin (Rr), found in anaerobic sulphate-reducing bacteria [PMID: 7830612], is a fusion protein containing an N-terminal diiron-binding domain and a C-terminal domain homologous to rubredox [...]
CDZ75381.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1243Hypothetical protein.
CDZ75382.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1244Hypothetical protein.
CDZ75383.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1245Radical SAM domain protein; High confidence in function and specificity.
CDZ75384.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1246Hypothetical protein; Family membership.
CDZ75385.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1247Hypothetical protein; Family membership.
CDZ75386.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1248Transposase; High confidence in function and specificity.
CDZ75387.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1249Rubredoxin; Family membership.
CDZ75388.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1250Hypothetical protein; High confidence in function and specificity.
CDZ75389.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1251Putative membrane protein; High confidence in function and specificity.
CDZ75390.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_12528-oxoguanine DNA glycosylase; High confidence in function and specificity.
rex protein networkhttps://string-db.org/network/1912856.ING2D1G_1253CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
CDZ75392.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1254ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily, which uses the hydrolysis of ATP to energise diverse biological systems. ABC transporters minimally consist of two conserved [...]
CDZ75393.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1255Hypothetical protein.
CDZ75394.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1256Hypothetical protein; Family membership.
CDZ75395.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1257This family includes glycerate kinase 2 (EC), which catalyses the phosphorylation of (R)-glycerate to 3-phospho-(R)-glycerate in the presence of ATP. These proteins consist of two different alpha [...]
garR protein networkhttps://string-db.org/network/1912856.ING2D1G_12582-hydroxy-3-oxopropionate reductase; D-glycerate + NAD(P)+ = 2-hydroxy-3-oxopropanoate + NAD(P)H; High confidence in function and specificity.
CDZ75397.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1259Hypothetical protein; Family membership.
CDZ75398.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1260Putative membrane protein.
CDZ75399.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1261Nitroreductases are a family of evolutionarily related proteins involved in the reduction of nitrogen-containing compounds, including those containing the nitro functional group. Members of this [...]
CDZ75400.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1262Diacylglycerol kinase family enzyme; Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. The catalytic domain is assumed from the finding of bacterial homologues [...]
hisC protein networkhttps://string-db.org/network/1912856.ING2D1G_1263Histidinol-phosphate aminotransferase; L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate; High confidence in function and specificity; Belongs to the [...]
hisS protein networkhttps://string-db.org/network/1912856.ING2D1G_1264Histidine-tRNA ligase; ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His); High confidence in function and specificity.
CDZ75403.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1265NA+/H+ antiporter NHAC; This family includes integral membrane proteins, some of which are NA+/H+ antiporters; High confidence in function and specificity.
murI-2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1266Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
CDZ75405.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1267Guanylate kinase, also called GMP kinase, is essential for recycling GMP and indirectly, cGMP. This enzyme transfers a phosphate from ATP to GMP, yielding ADP and GDP. Guanylate kinase is a highl [...]
CDZ75406.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1268Na/Pi-cotransporter family protein; Na+/phosphate symporter [Inorganic ion transport and metabolism]; High confidence in function and specificity.
CDZ75407.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1269Putative secreted protein.
CDZ75408.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1270Hypothetical protein; Family membership.
CDZ75409.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1271Hypothetical protein; Family membership.
CDZ75410.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1272Hypothetical protein; Uroporphyrinogen decarboxylase (URO-D), the fifth enzyme of the haem biosynthetic pathway, catalyses the sequential decarboxylation of the four acetyl side chains of uroporp [...]
CDZ75411.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1273Hypothetical protein; High confidence in function and specificity.
CDZ75412.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1274Hypothetical protein; Family membership.
CDZ75413.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1275Hypothetical protein; Family membership.
CDZ75414.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1276UPF0597 protein; High confidence in function and specificity; Belongs to the UPF0597 family.
CDZ75415.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1277Sigma-54 dependent transcriptional regulator; High confidence in function and specificity.
CDZ75416.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1278BadF/BadG/BcrA/BcrD ATPase family protein; High confidence in function and specificity.
CDZ75417.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1279Hypothetical protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
rpsR protein networkhttps://string-db.org/network/1912856.ING2D1G_1280Hypothetical protein; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal pr [...]
CDZ75419.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1281Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of act [...]
rpsF protein networkhttps://string-db.org/network/1912856.ING2D1G_1282Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
murA1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1283UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
CDZ75422.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1284Permease domain protein; High confidence in function and specificity.
CDZ75423.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1285ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters, ABC transporters belong to the ATP-Binding Cassette superfamily, which uses the hydrolysis of A [...]
CDZ75424.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1286Hypothetical protein; Family membership.
CDZ75425.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1287Hypothetical protein; Family membership.
CDZ75426.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1288Putative membrane protein.
artM protein networkhttps://string-db.org/network/1912856.ING2D1G_1289Arginine transport ATP-binding protein ArtM; ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters, ABC transporters belong to the ATP-Binding Cassett [...]
glnP protein networkhttps://string-db.org/network/1912856.ING2D1G_1290ABC transporters are minimally constituted of two conserved regions: a highly conserved ATP binding cassette (ABC) and a less conserved transmembrane domain (TMD). These regions can be found on t [...]
CDZ75429.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1291Arginine/lysine/histidine transporter system substrate-binding protein; High confidence in function and specificity.
CDZ75430.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1292Diacylglycerol kinase catalytic subunit; The Escherichia coli member of this family, YegS, has been purified and shown to have phosphatidylglycerol kinase activity. DagK from Bacillus subtilis ca [...]
CDZ75431.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1293Nitroreductase; High confidence in function and specificity.
fabG3 protein networkhttps://string-db.org/network/1912856.ING2D1G_1294The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD-or NADP-dependent oxidoreductases. As the first member of this family t [...]
CDZ75433.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1295Hypothetical protein; Family membership.
hsp20 protein networkhttps://string-db.org/network/1912856.ING2D1G_1296Hsp20 is a mammalian small heat-shock protein family that occurs most abundantly in skeletal muscle and heart. It has a tendency to form dimers, via a disulphide linkage formed by an N-terminal c [...]
CDZ75435.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1297Putative membrane protein.
CDZ75436.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1298Hypothetical protein; Family membership.
CDZ75437.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1299Hypothetical protein; Family membership.
CDZ75438.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1300Hypothetical protein; Family membership.
CDZ75439.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1301Hypothetical protein; High confidence in function and specificity.
CDZ75440.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1302Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need [...]
CDZ75441.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1303Family of patatin-like phospholipases consists of various patatin glycoproteins from the total soluble protein from potato tubers, and also some proteins found in vertebrates. Patatin is a storag [...]
mscL protein networkhttps://string-db.org/network/1912856.ING2D1G_1304Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within th [...]
CDZ75443.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1305His protein is found in the ComE operon for 'late competence' as characterized in B. subtilis. Proteins in this family contain homology to a cytidine/deoxycytidine deaminase domain family (pfam00 [...]
CDZ75444.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1306RNase H digests the RNA strand of an RNA/DNA hybrid. Important enzyme in retroviral replication cycle, and often found as a domain associated with reverse transcriptases. Structure is a mixed alp [...]
fda protein networkhttps://string-db.org/network/1912856.ING2D1G_1307Fructose-bisphosphate aldolase class 1; D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate; High confidence in function and specificity.
CDZ75446.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1308Metal- dependentamidase/aminoacylase/carboxypeptidase; High confidence in function and specificity.
groL protein networkhttps://string-db.org/network/1912856.ING2D1G_130960 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
groS protein networkhttps://string-db.org/network/1912856.ING2D1G_1310Co-chaperonin GroES (HSP10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
CDZ75449.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1311Hypothetical protein; Family membership.
CDZ75450.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1312Mechanosensitive ion channel family protein; Two members of this protein family: Q57634 and Q58543 of M. jannaschii have been functionally characterised. Both proteins form mechanosensitive (MS) [...]
CDZ75451.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1313Hypothetical protein; High confidence in function and specificity.
CDZ75452.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1314Putative S-layer homology domain protein; High confidence in function and specificity.
purD protein networkhttps://string-db.org/network/1912856.ING2D1G_1315Phosphoribosylformylglycinamidine synthase; Phosphoribosylglycinamide synthetase catalyses the second step in the de novo biosynthesis of purine. The reaction catalysed by Phosphoribosylglycinami [...]
purH protein networkhttps://string-db.org/network/1912856.ING2D1G_1316Bifunctional purine biosynthesis protein PurH; 10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole [...]
purN protein networkhttps://string-db.org/network/1912856.ING2D1G_1317Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylg [...]
purM protein networkhttps://string-db.org/network/1912856.ING2D1G_1318Phosphoribosylformylglycinamidine cyclo-ligase; The purine biosynthetic pathway in procaryotes enlists eleven enzymes, six of which use ATP. Enzymes 5 and 6 of this pathway, formylglycinamide rib [...]
purF protein networkhttps://string-db.org/network/1912856.ING2D1G_1319Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
CDZ75458.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1320Putative membrane protein.
gcdB1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1321Na+-transporting oxaloacetate decarboxylase beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
CDZ75460.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1322Glutamate dehydrogenases (EC, EC, and EC) (GluDH) are enzymes that catalyse the NAD-and/or NADP-dependent reversible deamination of L-glutamate into alpha-ketoglutarate. GluDH isozymes are genera [...]
CDZ75461.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1323Formate/nitrite transporter; Proteins in this entry belong to the Formate-Nitrite Transporter (FNT) family (TC 2.A.44). The prokaryotic proteins of the FNT family probably function in the transpo [...]
CDZ75462.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1324UPF0317 protein; This family represents a conserved region approximately 150 residues long within a number of hypothetical bacterial and eukaryotic proteins of unknown function; High confidence i [...]
CDZ75463.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1325This domain forms the second subunit of allophanate hydrolase. In yeast urea amidolyase this domain is found between pfam00289 and pfam00364; High confidence in function and specificity.
CDZ75464.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1326Allophanate hydrolase; In bacteria, the second step in the urea degradation pathway is also the ATP-dependent allophanate hydrolase. The gene encoding this enzyme is found adjacent to the urea ca [...]
ycsG protein networkhttps://string-db.org/network/1912856.ING2D1G_1327Putative membrane protein; High confidence in function and specificity.
pxpA protein networkhttps://string-db.org/network/1912856.ING2D1G_1328Lactam utilization protein B; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
CDZ75467.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1329This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in pe [...]
CDZ75468.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1330Hypothetical protein.
CDZ75469.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1331Radical SAM proteins catalyse diverse reactions, including unusual methylations, isomerisation, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation; High confiden [...]
pncB protein networkhttps://string-db.org/network/1912856.ING2D1G_1332Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and [...]
CDZ75471.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1333Putative pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH [...]
CDZ75472.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1334Hypothetical protein; Family membership.
CDZ75473.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1335Hypothetical protein; High confidence in function and specificity.
fabZ protein networkhttps://string-db.org/network/1912856.ING2D1G_1336(3R)-hydroxymyristoyl-[acyl-carrier- protein]dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated [...]
fabF protein networkhttps://string-db.org/network/1912856.ING2D1G_13373-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
fabG5 protein networkhttps://string-db.org/network/1912856.ING2D1G_13383-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongati [...]
fabD protein networkhttps://string-db.org/network/1912856.ING2D1G_1339Malonyl CoA-acyl carrier protein transacylases transfer the malonyl moiety from coenzyme A to acyl-carrier protein. These include proteins involved in fatty acid biosynthesis, antibiotic bosynthe [...]
CDZ75478.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1340Nitronate monooxygenase (NMO), formerly referred to as 2-nitropropane dioxygenase (NPD) (, is an FMN-dependent enzyme that uses molecular oxygen to oxidize (anionic) alkyl nitronates and, in the [...]
fabK1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1341Enoyl-[acyl carrier protein] reductase II; 2-Nitropropane dioxygenase catalyses the oxidation of nitroalkanes into their corresponding carbonyl compounds and nitrite using eithr FAD or FMN as a c [...]
fabK3 protein networkhttps://string-db.org/network/1912856.ING2D1G_1342Enoyl-[acyl carrier protein] reductase II; Dioxygenases related to 2-nitropropane dioxygenase; High confidence in function and specificity.
fabH protein networkhttps://string-db.org/network/1912856.ING2D1G_13433-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first [...]
accA protein networkhttps://string-db.org/network/1912856.ING2D1G_1344Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on [...]
accD protein networkhttps://string-db.org/network/1912856.ING2D1G_1345Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin [...]
accC1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1346Acetyl-CoA carboxylase, biotin carboxylase; ATP + biotin-[carboxyl-carrier-protein] + HCO(3)(-) <=> ADP + phosphate + carboxy-biotin-[carboxyl-carrier-protein]; High confidence in function and sp [...]
CDZ75485.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1347acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the car [...]
acpP-2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1348Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
tuf2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1349Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; High confidence in function and specificity.
gloA protein networkhttps://string-db.org/network/1912856.ING2D1G_1350Lactoylglutathione lyase; Glyoxalase I (EC) catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid. Glyoxalase I is an ubiquitous [...]
CDZ75489.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1351Hypothetical protein; High confidence in function and specificity.
CDZ75490.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1352Hypothetical protein; High confidence in function and specificity.
CDZ75491.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1353LYSR family transcriptional regulatory protein; The structure of this domain is known and is; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
CDZ75492.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1354This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in pe [...]
glmM protein networkhttps://string-db.org/network/1912856.ING2D1G_1355Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
CDZ75494.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1356tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; High confidence in function and specificity.
CDZ75495.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1357Hypothetical protein; Family membership.
CDZ75496.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1358Copper amine oxidases catalyse the oxidative deamination of primary amines to the corresponding aldehydes, while reducing molecular oxygen to hydrogen peroxide. These enzymes are dimers of identi [...]
leuB protein networkhttps://string-db.org/network/1912856.ING2D1G_13593-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
leuD protein networkhttps://string-db.org/network/1912856.ING2D1G_13603-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. Le [...]
leuC protein networkhttps://string-db.org/network/1912856.ING2D1G_13613-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
leuA protein networkhttps://string-db.org/network/1912856.ING2D1G_13622-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isoprop [...]
etfB3 protein networkhttps://string-db.org/network/1912856.ING2D1G_1363An electron transfer flavoprotein (ETF) or electron transfer flavoprotein complex (CETF) is a flavoprotein located on the matrix face of the inner mitochondrial membrane and functions as a specif [...]
eftA protein networkhttps://string-db.org/network/1912856.ING2D1G_1364An electron transfer flavoprotein (ETF) or electron transfer flavoprotein complex (CETF) is a flavoprotein located on the matrix face of the inner mitochondrial membrane and functions as a specif [...]
CDZ75503.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1365Hypothetical protein; Family membership.
CDZ75504.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1366Hypothetical protein; High confidence in function and specificity.
CDZ75505.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1367S-layer family domain protein; High confidence in function and specificity.
CDZ75506.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1368Putative ABC transporter ATP-binding protein TM_0352; High confidence in function and specificity.
engB protein networkhttps://string-db.org/network/1912856.ING2D1G_1369Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. E [...]
lon protein networkhttps://string-db.org/network/1912856.ING2D1G_1370Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular home [...]
clpX protein networkhttps://string-db.org/network/1912856.ING2D1G_1371ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in th [...]
clpP protein networkhttps://string-db.org/network/1912856.ING2D1G_1372ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
tig protein networkhttps://string-db.org/network/1912856.ING2D1G_1373Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs t [...]
CDZ75512.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1374Hypothetical protein.
proS protein networkhttps://string-db.org/network/1912856.ING2D1G_1375Proline-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(P [...]
murI protein networkhttps://string-db.org/network/1912856.ING2D1G_1376Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
CDZ75515.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1377Hypothetical protein; High confidence in function and specificity.
CDZ75516.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1378Hypothetical protein; High confidence in function and specificity.
CDZ75517.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1379Putative haloacid dehalogenase, IA family protein; The haloacid dehydrogenase (HAD) superfamily includes phosphatases, phosphonatases, P-type ATPases, beta-phosphoglucomutases, phosphomannomutase [...]
raiA protein networkhttps://string-db.org/network/1912856.ING2D1G_1381Ribosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present d [...]
CDZ75519.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1382Hypothetical protein; High confidence in function and specificity.
CDZ75520.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1383Hypothetical protein.
CDZ75521.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1384This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90; Family membership.
CDZ75522.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1385Sensor histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine; High confidence in function and specificity.
CDZ75523.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1386DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain [Signal transduction mechanisms, Transcription]; High confidence in function and specificity.
CDZ75524.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1387His family acts as a virulence factor. In Bordetella pertussis, brkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease [...]
CDZ75525.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1388Predicted amidophosphoribosyltransferases [General function prediction only]; High confidence in function and specificity.
recD2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1389Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase a [...]
metK protein networkhttps://string-db.org/network/1912856.ING2D1G_1390S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formati [...]
CDZ75528.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1391Putative permease; High confidence in function and specificity.
CDZ75529.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1392seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further c [...]
trxB protein networkhttps://string-db.org/network/1912856.ING2D1G_1393Thioredoxin reductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger F [...]
fni protein networkhttps://string-db.org/network/1912856.ING2D1G_1394Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, [...]
CDZ75532.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1395Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
CDZ75533.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1396UPF0042 nucleotide-binding protein; Displays ATPase and GTPase activities.
murB protein networkhttps://string-db.org/network/1912856.ING2D1G_1397UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
CDZ75535.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1398Hypothetical protein; Family membership.
CDZ75536.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1399Hypothetical protein; High confidence in function and specificity.
CDZ75537.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1400Hypothetical protein; Family membership.
CDZ75538.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1401Macro domain-containing protein MA_1614; This domain is an ADP-ribose binding module. It is found in a number of otherwise unrelated proteins. It is found at the C-terminus of the macro-H2A histo [...]
etfA3 protein networkhttps://string-db.org/network/1912856.ING2D1G_1402An electron transfer flavoprotein (ETF) or electron transfer flavoprotein complex (CETF) is a flavoprotein located on the matrix face of the inner mitochondrial membrane and functions as a specif [...]
CDZ75540.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1403An electron transfer flavoprotein (ETF) or electron transfer flavoprotein complex (CETF) is a flavoprotein located on the matrix face of the inner mitochondrial membrane and functions as a specif [...]
bcd3 protein networkhttps://string-db.org/network/1912856.ING2D1G_1404Acyl-CoA dehydrogenase, short-chain specific; Butanoyl-CoA + electron-transfer flavoprotein <=> 2-butenoyl-CoA + reduced electron-transfer flavoprotein; High confidence in function and specificit [...]
frc protein networkhttps://string-db.org/network/1912856.ING2D1G_1405This enzyme, formyl-CoA transferase, transfers coenzyme A from formyl-CoA to oxalate. It forms a pathway, together with oxalyl-CoA decarboxylase, for oxalate degradation; decarboxylation by the l [...]
CDZ75543.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1406Putative membrane protein.
bcd5 protein networkhttps://string-db.org/network/1912856.ING2D1G_1407Acyl-CoA dehydrogenase, short-chain specific; Butanoyl-CoA + electron-transfer flavoprotein <=> 2-butenoyl-CoA + reduced electron-transfer flavoprotein; High confidence in function and specificit [...]
hbd protein networkhttps://string-db.org/network/1912856.ING2D1G_14083-hydroxyacyl-CoA dehydrogenase (EC) (HCDH) [PUBMED:3479790] is an enzyme involved in fatty acid metabolism, it catalyzes the reduction of 3-hydroxyacyl-CoA to 3-oxoacyl-CoA. Most eukaryotic cell [...]
crt protein networkhttps://string-db.org/network/1912856.ING2D1G_14093-hydroxbutyryl-CoA dehydratase (crotonase; EC), a bacterial enzyme involved in the butyrate/butanol-producing pathway; High confidence in function and specificity; Belongs to the enoyl-CoA hydra [...]
thlA protein networkhttps://string-db.org/network/1912856.ING2D1G_14102 acetyl-CoA <=> CoA + acetoacetyl-CoA; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
CDZ75548.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1411An UDP-N-acetylglucosamine 2-epimerase is an enzyme that catalyzes the chemical reaction, UDP-N-acetyl-D-glucosamine ightleftharpoons UDP-N-acetyl-D-mannosamine; High confidence in function and [...]
CDZ75549.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1412Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase; High confidence in function and specificity.
upp protein networkhttps://string-db.org/network/1912856.ING2D1G_1413Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
ywlC protein networkhttps://string-db.org/network/1912856.ING2D1G_1414tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC [; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons be [...]
CDZ75552.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1415Hypothetical protein; High confidence in function and specificity.
CDZ75553.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1416This family contains the bacterial Ornithine cyclodeaminase enzyme, which catalyses the deamination of ornithine to proline; High confidence in function and specificity.
CDZ75554.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1417Putative NAD/nadp octopine/nopaline dehydrogenase; This group of enzymes act on the CH-NH substrate bond using NAD(+) or NADP(+) as an acceptor. The Pfam family consists mainly of octopine and no [...]
CDZ75555.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1418Sodium/glutamate symporter superfamily; High confidence in function and specificity.
hgdB protein networkhttps://string-db.org/network/1912856.ING2D1G_1419(R)-2-hydroxyglutaryl-CoA dehydratase subunit beta; Catalyzes the reversible dehydration of 2-hydroxyglutaryl-CoA to glutaconyl-CoA. This is a key step in the fermentation of glutamate; High conf [...]
hgdA protein networkhttps://string-db.org/network/1912856.ING2D1G_1420(R)-2-hydroxyglutaryl-CoA dehydratase alpha subunit; Degradation of glutamate via the hydroxyglutarate pathway involves the syn-elimination of water from 2-hydroxyglutaryl-CoA. This anaerobic pro [...]
hgdC protein networkhttps://string-db.org/network/1912856.ING2D1G_1421Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid transport and metabolism]; High confidence in function and specificity.
gcdA protein networkhttps://string-db.org/network/1912856.ING2D1G_1422Glutaconyl-CoA decarboxylase subunit alpha; 4-carboxybut-2-enoyl-CoA <=> but-2-enoyl-CoA + CO(2); High confidence in function and specificity.
gctB protein networkhttps://string-db.org/network/1912856.ING2D1G_1423Glutaconate CoA-transferase subunit B; High confidence in function and specificity.
gctA protein networkhttps://string-db.org/network/1912856.ING2D1G_1424Glutaconate CoA-transferase subunit A; High confidence in function and specificity.
gcdB3 protein networkhttps://string-db.org/network/1912856.ING2D1G_1425Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
CDZ75563.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1426Biotin carboxyl carrier protein; Family membership.
CDZ75564.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1427Hypothetical protein; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the OadG family.
CDZ75565.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1428Hypothetical protein; High confidence in function and specificity.
CDZ75566.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1429Fe-hydrogenase large subunit family protein; Iron only hydrogenase large subunit, C-terminal domain (pfam02906); High confidence in function and specificity.
sigI protein networkhttps://string-db.org/network/1912856.ING2D1G_1430Putative RNA polymerase sigma-I factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; Belongs to the sigma [...]
CDZ75568.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1431Putative membrane protein.
CDZ75569.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1432Hypothetical protein; Family membership.
CDZ75570.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1433L-Ala-DL-Glu_epimerase; L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of th [...]
CDZ75571.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1434Hypothetical protein; High confidence in function and specificity.
appF protein networkhttps://string-db.org/network/1912856.ING2D1G_1435Oligopeptide transport ATP-binding protein AppF; High confidence in function and specificity; Belongs to the ABC transporter superfamily.
appD protein networkhttps://string-db.org/network/1912856.ING2D1G_1436Oligopeptide transport ATP-binding protein AppD; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily, which uses the hydrolysis of ATP to energise diverse biological systems. AB [...]
CDZ75574.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1437ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism]; High confidence in function and specific [...]
CDZ75575.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1438ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism]; High confidence in function and specific [...]
CDZ75576.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1439PBP2_NikA_DppA_OppA_like; This family represents the periplasmic substrate-binding domain of nickel/dipeptide/oligopeptide transport systems, which function in the import of nickel and peptides, [...]
CDZ75577.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1440Putative N-acyltransferase; This domain catalyses N-acetyltransferase reactions; Family membership.
CDZ75578.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1441Putative helix-turn-helix protein; High confidence in function and specificity.
CDZ75579.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1442Glycosyl transferases; Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transf [...]
CDZ75580.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1443Putative membrane protein.
CDZ75581.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1444Threonine-phosphate decarboxylase; Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin [...]
CDZ75582.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1445L-threonine <=> glycine + acetaldehyde; High confidence in function and specificity.
CDZ75583.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1446The alpha/beta hydrolase fold [PMID: 1409539] is common to a number of hydrolytic enzymes of widely differing phylogenetic origin and catalytic function. The core of each enzyme is an alpha/beta- [...]
CDZ75584.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1447Putative membrane protein.
surE protein networkhttps://string-db.org/network/1912856.ING2D1G_1448Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
CDZ75586.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1449Metallo-beta-lactamase superfamily hydrolase; Apart from the beta-lactamases and metallo-beta-lactamases, a number of other proteins contain this domain [PUBMED:7588620]. These proteins include t [...]
CDZ75587.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_14502-Hacid_dh_4; 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyr [...]
CDZ75588.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1451Hypothetical protein; High confidence in function and specificity.
CDZ75589.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1452Putative membrane protein.
CDZ75590.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1453Sensory transduction histidine kinase; High confidence in function and specificity.
walR protein networkhttps://string-db.org/network/1912856.ING2D1G_1454Transcriptional regulatory protein WalR; Two-component signal transduction systems enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions [ [...]
nfo protein networkhttps://string-db.org/network/1912856.ING2D1G_1455Putative endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyri [...]
CDZ75593.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1456Putative membrane protein; High confidence in function and specificity.
dctP protein networkhttps://string-db.org/network/1912856.ING2D1G_1457Sodium:dicarboxylate symporter family; It has been shown [PUBMED:8031825] that integral membrane proteins that mediate the uptake of a wide variety of molecules with the concomitant uptake of sod [...]
sdhA protein networkhttps://string-db.org/network/1912856.ING2D1G_1458L-serine dehydratase, alpha chain; L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulphur-dependent [...]
sdhB protein networkhttps://string-db.org/network/1912856.ING2D1G_1459L-serine dehydratase is found as a heterodimer of alpha and beta chain or as a fusion of the two chains in a single protein. This enzyme catalyses the deamination of serine to form pyruvate and i [...]
pyrC protein networkhttps://string-db.org/network/1912856.ING2D1G_1460Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
CDZ75598.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1461Hypothetical protein; Family membership.
folD protein networkhttps://string-db.org/network/1912856.ING2D1G_1462Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahy [...]
ypfJ protein networkhttps://string-db.org/network/1912856.ING2D1G_1463Putative metalloprotease; High confidence in function and specificity.
ybaK protein networkhttps://string-db.org/network/1912856.ING2D1G_1464Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase; This model represents the YbaK family, bacterial proteins whose full length sequence is homologous to an insertion domain in proline-tRNA ligases. The domai [...]
aroQ protein networkhttps://string-db.org/network/1912856.ING2D1G_14653-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
aroK protein networkhttps://string-db.org/network/1912856.ING2D1G_1466Shikimate 5-dehydrogenase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
CDZ75604.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1467Chorismate mutase / prephenate dehydratase.The bifunctional P-protein, which plays a central role in phenylalanine biosynthesis, contains two catalytic domains (chorismate mutase and prephenate d [...]
aroC protein networkhttps://string-db.org/network/1912856.ING2D1G_1468Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
aroA protein networkhttps://string-db.org/network/1912856.ING2D1G_14693-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
CDZ75607.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_14703-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
CDZ75608.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1471Hypothetical protein; This entry represents prephenate dehydrogenase (PDHG), an enzyme involved in tyrosine biosynthesis [PMID: 21798280], Three enzymes catalyse the conversion of chorismate to h [...]
aroF protein networkhttps://string-db.org/network/1912856.ING2D1G_14723-Deoxy-D-arabinoheptulosonate 7-phosphate (DAHP) synthase is the first enzyme in a series of metabolic reactions known as the shikimate pathway, which is responsible for the biosynthesis of the [...]
CDZ75610.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1473GT8_A4GalT_like; The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bact [...]
CDZ75611.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1474Putative membrane protein.
ftsH3 protein networkhttps://string-db.org/network/1912856.ING2D1G_1475ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral memb [...]
CDZ75613.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1476Hypothetical protein; Family membership.
CDZ75614.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1477Hypothetical protein; High confidence in function and specificity.
CDZ75615.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1478Putative membrane protein.
sigI-2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1479Putative RNA polymerase sigma factor SigI; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; Belongs to the si [...]
CDZ75617.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1480Hypothetical protein; Family membership.
CDZ75618.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1481Hypothetical protein; Family membership.
CDZ75619.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1482Hypothetical protein; Family membership.
CDZ75620.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1483Hypothetical protein; Family membership.
CDZ75621.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1484Hypothetical protein; High confidence in function and specificity.
CDZ75622.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1485Putative membrane protein.
CDZ75623.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1486Hypothetical protein; High confidence in function and specificity.
CDZ75624.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1487Hypothetical protein; High confidence in function and specificity.
CDZ75625.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1488Hypothetical protein; High confidence in function and specificity.
CDZ75626.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1489Hypothetical protein; High confidence in function and specificity.
CDZ75627.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1490Hypothetical protein.
CDZ75628.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1491Putative membrane protein.
CDZ75629.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1492Hypothetical protein; Family membership.
CDZ75631.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1494TetR family transcriptional regulator; High confidence in function and specificity.
CDZ75632.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1495Major Facilitator Superfamily transporter; High confidence in function and specificity.
CDZ75633.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1496ABC transporter permease; High confidence in function and specificity.
CDZ75634.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1497In molecular biology, ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters, ABC transporters belong to the ATP-Binding Cassette superfamily, which us [...]
CDZ75635.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1498Hypothetical protein; Family membership.
CDZ75636.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1499Putative membrane protein.
CDZ75637.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1500Hypothetical protein; Family membership.
CDZ75638.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1501Hypothetical protein.
CDZ75639.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1502SDR_c; SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an N [...]
CDZ75640.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1503Metallo-beta-lactamase domain protein; Apart from the beta-lactamases a number of other proteins contain this domain. These proteins include thiolesterases, members of the glyoxalase II family, t [...]
CDZ75641.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1504Hypothetical protein; High confidence in function and specificity.
CDZ75642.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1505Hypothetical protein.
hcp protein networkhttps://string-db.org/network/1912856.ING2D1G_1506Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
CDZ75644.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1507Hypothetical protein; Family membership.
CDZ75645.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1508Hypothetical protein; High confidence in function and specificity.
CDZ75646.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1509Hypothetical protein; High confidence in function and specificity.
CDZ75647.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1510Hypothetical protein; Family membership.
CDZ75648.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1511Hypothetical protein; Family membership.
CDZ75649.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1512Group II intron reverse transcriptase/maturase; Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobi [...]
CDZ75650.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1513Hypothetical protein; Family membership.
CDZ75651.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1514Sortase B (SrtB) or subfamily-2 sortases are membrane cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. [...]
CDZ75652.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1515Hypothetical protein; Family membership.
CDZ75653.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1516The large serine recombinases (LSRs) are DNA-rearranging enzymes that are members of the serine recombinase or resolvase/invertase superfamily. Most resolvases/invertases have a catalytic domain [...]
CDZ75654.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1517Putative recombinase; This domain is usually found associated with pfam00239 in putative integrases/recombinases of mobile genetic elements of diverse bacteria and phages; High confidence in func [...]
CDZ75655.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1518DNA recombinase, putative; This domain is usually found associated with INTERPRO in putative integrases/recombinases of mobile genetic elements of diverse bacteria and phages; High confidence in [...]
CDZ75656.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1519Hypothetical protein; Family membership.
CDZ75657.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1520DNA polymerase I family protein; The DNA polymerases are enzymes that create DNA molecules by assembling nucleotides, the building blocks of DNA. These enzymes are essential to DNA replication an [...]
CDZ75658.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1521Helix-turn-helix XRE-family like proteins; Family membership.
CDZ75659.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1522Hypothetical protein; High confidence in function and specificity.
CDZ75660.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1523Hypothetical protein; High confidence in function and specificity.
CDZ75661.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1524Hypothetical protein; High confidence in function and specificity.
CDZ75662.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1525Helix-turn-helix XRE-family like proteins; Family membership.
CDZ75663.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1526Hypothetical protein; High confidence in function and specificity.
CDZ75664.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1527The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domai [...]
CDZ75665.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1528Hypothetical protein.
CDZ75666.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1529Hypothetical protein; High confidence in function and specificity; Belongs to the 'phage' integrase family.
CDZ75667.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1530Hypothetical protein.
CDZ75668.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1531Putative membrane protein.
CDZ75669.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1532Hypothetical protein; High confidence in function and specificity.
CDZ75670.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1533Putative protein; High confidence in function and specificity.
ermGT protein networkhttps://string-db.org/network/1912856.ING2D1G_1534Ribosomal RNA adenine dimethylase; The bacterial enzyme KsgA catalyses the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases in 16S [...]
CDZ75672.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1535Hypothetical protein.
CDZ75673.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1536Hyothetical protein; Family membership.
CDZ75674.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1537Resolvase, N-terminal domain protein; High confidence in function and specificity.
CDZ75675.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1538Translation elongation factor EF-G, a GTPase [Translation, ribosomal structure and biogenesis]; High confidence in function and specificity.
CDZ75676.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1539Hypothetical protein; Family membership.
CDZ75677.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1540Hypothetical protein.
trmA protein networkhttps://string-db.org/network/1912856.ING2D1G_154123S rRNA methyluridine methyltransferase; High confidence in function and specificity; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
CDZ75680.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1543Putative D-lactate dehydrogenase; (R)-lactate + NAD(+) <=> pyruvate + NADH; High confidence in function and specificity.
CDZ75681.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1544TRAP-type C4-dicarboxylate transport system; Tripartite ATP-independent periplasmic transporters (TRAP transporters) are a large family of solute transporters found in bacteria and archaea, but n [...]
CDZ75682.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1545Hypothetical protein; Family membership.
CDZ75683.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1546PBP2_TRAP_DctP10; This subgroup includes TRAP transporter DctP10 and its similar proteins. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. [...]
CDZ75684.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1547Metallo-beta-lactamase superfamily; Apart from the beta-lactamases a number of other proteins contain this domain. These proteins include thiolesterases, members of the glyoxalase II family, that [...]
CDZ75685.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1548SAF_AH_GD; Altronate dehydratase converts D-altronate into 2-dehydro-3-deoxy-D-gluconate and is part of a bacterial pathway for the degradation of D-galacturonate. D-galactarate dehydratase elimi [...]
CDZ75686.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1549Altronate hydrolase (Altronic acid hydratase); Family members include the C termini of D-galactarate dehydratase (which is thought to catalyse the reaction D-galactarate = 5-keto-4-deoxy-D-glucar [...]
CDZ75687.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1550Type I restriction system adenine methylase HsdM; Type I enzymes cleave at sites remote from recognition site; require both ATP and S-adenosyl-L-methionine to function; multifunctional protein wi [...]
CDZ75688.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1551Putative RNA methyltransferase TTE1797; Methyltransferases (MTs) constitute an important class of enzymes present in every life form. They transfer a methyl group most frequently from S-adenosyl [...]
CDZ75689.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1552Putative polysaccharide deacetylase family protein; This family contains an uncharacterized protein yadE from Escherichia coli and its bacterial homologs. Although its molecular function remains [...]
CDZ75690.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1553LysR family transcriptional regulator; This group of sequences represents a number of related clades with numerous examples of members adjacent to operons for the degradation of 2-aminoethylphosp [...]
CDZ75691.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1554This entry represents a subset of the broader family of phosphate/phosphonate binding protein ABC transporter components. Many of the proteins in this entry can be associated with pathways for th [...]
phnC2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1555Phosphonates import ATP-binding protein PhnC 2; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the [...]
CDZ75693.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1556Phosphonate ABC transporter inner membrane subunit; ABC transporters are minimally constituted of two conserved regions: a highly conserved ATP binding cassette (ABC) and a less conserved transme [...]
CDZ75694.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1557Type I phosphodiesterase/nucleotide pyrophosphatase; This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase i / nucleotide [...]
purC protein networkhttps://string-db.org/network/1912856.ING2D1G_1558Phosphoribosylaminoimidazole- succinocarboxamidesynthase; ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate <=> ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)im [...]
CDZ75696.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1559Hypothetical protein; Family membership.
CDZ75697.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1560Alkaline phosphatase (ALP, ALKP, ALPase, Alk Phos) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. Th [...]
CDZ75698.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1561Flagellum-specific peptidoglycan hydrolase FlgJ [Cell wall/membrane/envelope biogenesis, Cell motility]; High confidence in function and specificity.
CDZ75699.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1562RNA polymerase sigma-54 factor; A sigma factor is a DNA-binding protein protein that binds to the DNA-directed RNA polymerase core to produce the holoenzyme capable of initiating transcription at [...]
CDZ75700.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1563Hypothetical protein; High confidence in function and specificity.
tadA protein networkhttps://string-db.org/network/1912856.ING2D1G_1564Cytidine/deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase [...]
CDZ75702.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1565D-isomer specific 2-hydroxyacid dehydrogenase; This domain is inserted into the catalytic domain, the large dehydrogenase and D-lactate dehydrogenase families in SCOP. N-terminal portion of which [...]
CDZ75703.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1566TRAP transporters; Tripartite ATP-independent periplasmic transporters are a large family of solute transporters found in bacteria and archaea, but not in eukaryotes, that appear to be specific f [...]
CDZ75704.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1567TRAP transporters; Tripartite ATP-independent periplasmic transporters are a large family of solute transporters found in bacteria and archaea, but not in eukaryotes, that appear to be specific f [...]
CDZ75705.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1568TRAP transporter; Tripartite ATP-independent periplasmic transporters (TRAP transporters) are a large family of solute transporters found in bacteria and archaea, but not in eukaryotes, that appe [...]
CDZ75706.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1569Hypothetical protein; High confidence in function and specificity.
CDZ75707.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1570Hypothetical protein; High confidence in function and specificity.
nimB protein networkhttps://string-db.org/network/1912856.ING2D1G_1572Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily [Defense mechanisms]; High confidence in function and specificity.
CDZ75709.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1573Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; High confidence in function and specificity.
CDZ75710.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1574RpiR family transcriptional regulator; High confidence in function and specificity.
CDZ75711.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1575Peptidase family T4; This group of serine peptidases belong to MEROPS peptidase family S58 (DmpA aminopeptidase family, clan PB(S)). The protein fold of the peptidase unit for members of this fam [...]
CDZ75712.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1576Putative secreted protein.
CDZ75713.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1577Hemolysin; Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes, such as the covalent binding of the pyridoxal-phosphate group to a lysine residue [...]
CDZ75714.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1578ABC transporter permease; ABC-type proline/glycine betaine transport systems, periplasmic components; High confidence in function and specificity.
opuAA protein networkhttps://string-db.org/network/1912856.ING2D1G_1579Glycine betaine transport ATP-binding protein OpuAA; High confidence in function and specificity.
pyk protein networkhttps://string-db.org/network/1912856.ING2D1G_1580ATP + pyruvate = ADP + phosphoenolpyruvate; High confidence in function and specificity; Belongs to the pyruvate kinase family.
CDZ75717.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1581D-3-phosphoglycerate dehydrogenase; 3-phospho-D-glycerate + NAD+ = 3-phosphonooxypyruvate + NADH, 2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH; High confidence in function and specificity; B [...]
CDZ75718.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1582Hypothetical protein.
CDZ75719.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1583Hypothetical protein; Family membership.
CDZ75720.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1584Hypothetical protein.
CDZ75721.2 protein networkhttps://string-db.org/network/1912856.ING2D1G_1585Hypothetical protein; Family membership.
CDZ75722.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1586Stage 0 sporulation protein J; High confidence in function and specificity; Belongs to the ParB family.
soj protein networkhttps://string-db.org/network/1912856.ING2D1G_1587Inhibits the initiation of sporulation, Spo0J antagonizes this inhibition. Soj ultimately inhibits the activation (phosphorylation) of Spo0A; High confidence in function and specificity.
rsmG protein networkhttps://string-db.org/network/1912856.ING2D1G_1588Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
mnmG protein networkhttps://string-db.org/network/1912856.ING2D1G_1589tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
mnmE protein networkhttps://string-db.org/network/1912856.ING2D1G_1590tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
CDZ75727.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1591Hypothetical protein; High confidence in function and specificity.
CDZ75728.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1592Putative membrane protein.
CDZ75729.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1593Hypothetical protein; Family membership.
CDZ75730.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1594Hypothetical protein; High confidence in function and specificity.
CDZ75731.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1595Hypothetical protein.
CDZ75732.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1596Putative membrane protein.
CDZ75733.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1597Putative membrane protein.
CDZ75734.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1598Putative tellurite resistance protein; This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance [PUBMED:9406390] and plasmid fertility [...]
CDZ75735.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1599Putative membrane protein.
CDZ75736.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1600Beta-lactamase; This entry represents a beta-lactamase structural motif, which contains a cluster of alpha-helices and an alpha/beta sandwich. In addition to beta-lactamases, this domain is also [...]
CDZ75737.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1601Hypothetical protein; High confidence in function and specificity.
CDZ75738.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1602L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]; High confidence in function and specificity.
CDZ75739.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1603Dipeptidase PepV; High confidence in function and specificity.
CDZ75740.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1604Hypothetical protein; High confidence in function and specificity.
CDZ75741.1 protein networkhttps://string-db.org/network/1912856.ING2D1G_1605Membrane protein insertase; High confidence in function and specificity.
rnpA protein networkhttps://string-db.org/network/1912856.ING2D1G_1606Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]