Organism Overview: Doolittlea endobia


 
lepA protein networkhttps://string-db.org/network/1778262.MHIR_DE00001Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon bac [...]
lepB protein networkhttps://string-db.org/network/1778262.MHIR_DE00002Signal peptidase I; Belongs to the peptidase S26 family.
rnc protein networkhttps://string-db.org/network/1778262.MHIR_DE00004Ribonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRN [...]
era protein networkhttps://string-db.org/network/1778262.MHIR_DE00005GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cyc [...]
suhB protein networkhttps://string-db.org/network/1778262.MHIR_DE00006Inositol-1-monophosphatase.
CUX96366.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00007Hypothetical protein.
fabI protein networkhttps://string-db.org/network/1778262.MHIR_DE00008Enoyl-[acyl-carrier-protein] reductase [NADH] FabI.
tsaB protein networkhttps://string-db.org/network/1778262.MHIR_DE00010tRNA threonylcarbamoyladenosine biosynthesis protein TsaB.
rluB protein networkhttps://string-db.org/network/1778262.MHIR_DE00011Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family.
zwf protein networkhttps://string-db.org/network/1778262.MHIR_DE00012Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
lptB protein networkhttps://string-db.org/network/1778262.MHIR_DE00014Lipopolysaccharide export system ATP-binding protein LptB.
lptA protein networkhttps://string-db.org/network/1778262.MHIR_DE00015Lipopolysaccharide export system protein LptA precursor; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. [...]
lptC protein networkhttps://string-db.org/network/1778262.MHIR_DE00016Lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitat [...]
kdsD protein networkhttps://string-db.org/network/1778262.MHIR_DE00018Arabinose 5-phosphate isomerase KdsD.
mlaF protein networkhttps://string-db.org/network/1778262.MHIR_DE00019Putative phospholipid import ATP-binding protein MlaF.
mlaE protein networkhttps://string-db.org/network/1778262.MHIR_DE00020Putative phospholipid ABC transporter permease protein MlaE.
mlaD protein networkhttps://string-db.org/network/1778262.MHIR_DE00021Putative phospholipid ABC transporter-binding protein MlaD.
mlaC protein networkhttps://string-db.org/network/1778262.MHIR_DE00022Putative phospholipid-binding protein MlaC precursor.
mlaB protein networkhttps://string-db.org/network/1778262.MHIR_DE00023Putative phospholipid ABC transporter-binding protein MlaB.
CUX96389.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00024Hypothetical protein.
ffh protein networkhttps://string-db.org/network/1778262.MHIR_DE00025Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nasce [...]
rpsP protein networkhttps://string-db.org/network/1778262.MHIR_DE0002630S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
rimM protein networkhttps://string-db.org/network/1778262.MHIR_DE00027Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. [...]
trmD protein networkhttps://string-db.org/network/1778262.MHIR_DE00028tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rplS protein networkhttps://string-db.org/network/1778262.MHIR_DE0002950S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
ompC protein networkhttps://string-db.org/network/1778262.MHIR_DE00031Outer membrane protein C precursor.
bolA protein networkhttps://string-db.org/network/1778262.MHIR_DE00032Transcriptional regulator BolA; Belongs to the BolA/IbaG family.
murA protein networkhttps://string-db.org/network/1778262.MHIR_DE00033UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
degQ protein networkhttps://string-db.org/network/1778262.MHIR_DE00034Periplasmic pH-dependent serine endoprotease DegQ precursor; Belongs to the peptidase S1C family.
rplM protein networkhttps://string-db.org/network/1778262.MHIR_DE0003650S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
rpsI protein networkhttps://string-db.org/network/1778262.MHIR_DE0003730S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
ubiE_1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00038Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE.
mutS2 protein networkhttps://string-db.org/network/1778262.MHIR_DE00039Endonuclease MutS2.
CUX96404.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00040Hypothetical protein.
pssA protein networkhttps://string-db.org/network/1778262.MHIR_DE00041CDP-diacylglycerol--serine O-phosphatidyltransferase.
dnaQ protein networkhttps://string-db.org/network/1778262.MHIR_DE00042DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing funct [...]
rnhA protein networkhttps://string-db.org/network/1778262.MHIR_DE00043Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
ydjM protein networkhttps://string-db.org/network/1778262.MHIR_DE00044Inner membrane protein YdjM.
pheT protein networkhttps://string-db.org/network/1778262.MHIR_DE00046Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
pheS protein networkhttps://string-db.org/network/1778262.MHIR_DE00047Phenylalanine--tRNA ligase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
rplT protein networkhttps://string-db.org/network/1778262.MHIR_DE0004850S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
rpmI protein networkhttps://string-db.org/network/1778262.MHIR_DE0004950S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
infC protein networkhttps://string-db.org/network/1778262.MHIR_DE00050Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
thrS protein networkhttps://string-db.org/network/1778262.MHIR_DE00051Threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end [...]
metG_1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00052Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
metG_2 protein networkhttps://string-db.org/network/1778262.MHIR_DE00053Methionine--tRNA ligase.
nfuA protein networkhttps://string-db.org/network/1778262.MHIR_DE00057Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S protei [...]
mrdB protein networkhttps://string-db.org/network/1778262.MHIR_DE00058Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
spoVD protein networkhttps://string-db.org/network/1778262.MHIR_DE00059Stage V sporulation protein D; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
CUX96422.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00060Hypothetical protein.
holA protein networkhttps://string-db.org/network/1778262.MHIR_DE00061DNA polymerase III subunit delta.
lptE protein networkhttps://string-db.org/network/1778262.MHIR_DE00062LPS-assembly lipoprotein LptE precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD [...]
leuS protein networkhttps://string-db.org/network/1778262.MHIR_DE00063Leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
ispA protein networkhttps://string-db.org/network/1778262.MHIR_DE00068Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
xseB protein networkhttps://string-db.org/network/1778262.MHIR_DE00069Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleo [...]
thiI protein networkhttps://string-db.org/network/1778262.MHIR_DE00070tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the tran [...]
yajL protein networkhttps://string-db.org/network/1778262.MHIR_DE00071Chaperone protein YajL.
mutS protein networkhttps://string-db.org/network/1778262.MHIR_DE00072DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase act [...]
xseA protein networkhttps://string-db.org/network/1778262.MHIR_DE00073Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleo [...]
glk protein networkhttps://string-db.org/network/1778262.MHIR_DE00085Glucokinase; Belongs to the bacterial glucokinase family.
rpmG protein networkhttps://string-db.org/network/1778262.MHIR_DE0008850S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/1778262.MHIR_DE0008950S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
mreB protein networkhttps://string-db.org/network/1778262.MHIR_DE00090Rod shape-determining protein MreB.
mreC protein networkhttps://string-db.org/network/1778262.MHIR_DE00091Cell shape-determining protein MreC.
mreD protein networkhttps://string-db.org/network/1778262.MHIR_DE00092Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
typA protein networkhttps://string-db.org/network/1778262.MHIR_DE00094GTP-binding protein TypA/BipA.
mnmA protein networkhttps://string-db.org/network/1778262.MHIR_DE00095tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step o [...]
hflD protein networkhttps://string-db.org/network/1778262.MHIR_DE00096High frequency lysogenization protein HflD.
phoP_1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00098Virulence transcriptional regulatory protein PhoP.
phoQ protein networkhttps://string-db.org/network/1778262.MHIR_DE00099Virulence sensor histidine kinase PhoQ.
CUX96446.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00102Hypothetical protein.
CUX96447.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00103Hypothetical protein.
sodA protein networkhttps://string-db.org/network/1778262.MHIR_DE00104Superoxide dismutase [Mn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
clpP protein networkhttps://string-db.org/network/1778262.MHIR_DE00105ATP-dependent Clp protease proteolytic subunit precursor; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in t [...]
clpX protein networkhttps://string-db.org/network/1778262.MHIR_DE00106ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in th [...]
lon protein networkhttps://string-db.org/network/1778262.MHIR_DE00107Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular home [...]
hupB protein networkhttps://string-db.org/network/1778262.MHIR_DE00108DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
smpB protein networkhttps://string-db.org/network/1778262.MHIR_DE00109SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
rsmH protein networkhttps://string-db.org/network/1778262.MHIR_DE00111Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
CUX96455.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00112Hypothetical protein.
murE protein networkhttps://string-db.org/network/1778262.MHIR_DE00115UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (U [...]
murF protein networkhttps://string-db.org/network/1778262.MHIR_DE00116UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of mure [...]
mraY protein networkhttps://string-db.org/network/1778262.MHIR_DE00117Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...]
murD protein networkhttps://string-db.org/network/1778262.MHIR_DE00118UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF [...]
murG protein networkhttps://string-db.org/network/1778262.MHIR_DE00120Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
murC protein networkhttps://string-db.org/network/1778262.MHIR_DE00121UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
ftsA protein networkhttps://string-db.org/network/1778262.MHIR_DE00122Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
ftsZ protein networkhttps://string-db.org/network/1778262.MHIR_DE00123Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
lpxC protein networkhttps://string-db.org/network/1778262.MHIR_DE00124UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed st [...]
CUX96465.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00125Hypothetical protein.
secM protein networkhttps://string-db.org/network/1778262.MHIR_DE00126Secretion monitor.
secA protein networkhttps://string-db.org/network/1778262.MHIR_DE00127Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the [...]
erpA protein networkhttps://string-db.org/network/1778262.MHIR_DE00128Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG.
htpX protein networkhttps://string-db.org/network/1778262.MHIR_DE00129Protease HtpX; Belongs to the peptidase M48B family.
CUX96470.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00130Hypothetical protein.
proQ protein networkhttps://string-db.org/network/1778262.MHIR_DE00131ProP effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belon [...]
proS protein networkhttps://string-db.org/network/1778262.MHIR_DE00132Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA( [...]
lspA protein networkhttps://string-db.org/network/1778262.MHIR_DE00133Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
ileS protein networkhttps://string-db.org/network/1778262.MHIR_DE00134Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such err [...]
ribF protein networkhttps://string-db.org/network/1778262.MHIR_DE00135Riboflavin biosynthesis protein RibF.
rpsT protein networkhttps://string-db.org/network/1778262.MHIR_DE0013630S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
ribE protein networkhttps://string-db.org/network/1778262.MHIR_DE001376,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
nusB protein networkhttps://string-db.org/network/1778262.MHIR_DE00138N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of t [...]
pgpA protein networkhttps://string-db.org/network/1778262.MHIR_DE00139Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
nlpD protein networkhttps://string-db.org/network/1778262.MHIR_DE00141Murein hydrolase activator NlpD precursor.
cca protein networkhttps://string-db.org/network/1778262.MHIR_DE00142Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order [...]
CUX96482.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00143Hypothetical protein.
plsC protein networkhttps://string-db.org/network/1778262.MHIR_DE001441-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
parC protein networkhttps://string-db.org/network/1778262.MHIR_DE00145DNA topoisomerase 4 subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular [...]
tyrS protein networkhttps://string-db.org/network/1778262.MHIR_DE00146Tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tR [...]
ung protein networkhttps://string-db.org/network/1778262.MHIR_DE00147Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
pyrG protein networkhttps://string-db.org/network/1778262.MHIR_DE00153CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the fo [...]
eno protein networkhttps://string-db.org/network/1778262.MHIR_DE00154Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
pmbA protein networkhttps://string-db.org/network/1778262.MHIR_DE00155Peptidase PmbA.
galP protein networkhttps://string-db.org/network/1778262.MHIR_DE00156Galactose-proton symporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
tgt protein networkhttps://string-db.org/network/1778262.MHIR_DE00157Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in [...]
yajC protein networkhttps://string-db.org/network/1778262.MHIR_DE00158Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into memb [...]
secD protein networkhttps://string-db.org/network/1778262.MHIR_DE00159Protein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protei [...]
secF protein networkhttps://string-db.org/network/1778262.MHIR_DE00160Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete pr [...]
rpmE protein networkhttps://string-db.org/network/1778262.MHIR_DE0016150S ribosomal protein L31; Binds the 23S rRNA.
priA protein networkhttps://string-db.org/network/1778262.MHIR_DE00162Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its h [...]
rsmA protein networkhttps://string-db.org/network/1778262.MHIR_DE00163Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S part [...]
surA protein networkhttps://string-db.org/network/1778262.MHIR_DE00165Chaperone SurA precursor; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side ch [...]
lptD protein networkhttps://string-db.org/network/1778262.MHIR_DE00166LPS-assembly protein LptD precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
glyA protein networkhttps://string-db.org/network/1778262.MHIR_DE00168Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
CUX96502.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00169Hypothetical protein.
CUX96503.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00170Hypothetical protein.
CUX96504.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00172Putative inner membrane protein.
CUX96505.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00173Hypothetical protein.
iscS protein networkhttps://string-db.org/network/1778262.MHIR_DE00174Cysteine desulfurase.
CUX96507.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00176Hypothetical protein.
fmt protein networkhttps://string-db.org/network/1778262.MHIR_DE00177Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
def protein networkhttps://string-db.org/network/1778262.MHIR_DE00178Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
greA protein networkhttps://string-db.org/network/1778262.MHIR_DE00179Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
rlmE protein networkhttps://string-db.org/network/1778262.MHIR_DE00181Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
ftsH protein networkhttps://string-db.org/network/1778262.MHIR_DE00182ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral memb [...]
aroQ_1 protein networkhttps://string-db.org/network/1778262.MHIR_DE001863-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
accB_1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00187Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the c [...]
gmk protein networkhttps://string-db.org/network/1778262.MHIR_DE00188Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
rpoZ protein networkhttps://string-db.org/network/1778262.MHIR_DE00189DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alp [...]
spoT protein networkhttps://string-db.org/network/1778262.MHIR_DE00190Bifunctional (p)ppGpp synthase/hydrolase SpoT; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activi [...]
alaS protein networkhttps://string-db.org/network/1778262.MHIR_DE00194Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA( [...]
lysS protein networkhttps://string-db.org/network/1778262.MHIR_DE00195Lysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family.
prfB protein networkhttps://string-db.org/network/1778262.MHIR_DE00196Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
recJ protein networkhttps://string-db.org/network/1778262.MHIR_DE00197Single-stranded-DNA-specific exonuclease RecJ.
fldA protein networkhttps://string-db.org/network/1778262.MHIR_DE00198Flavodoxin-1; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
sppA protein networkhttps://string-db.org/network/1778262.MHIR_DE00199Protease 4.
CUX96525.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00200Hypothetical protein.
tktA protein networkhttps://string-db.org/network/1778262.MHIR_DE00201Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
CUX96528.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00203Hypothetical protein.
murJ protein networkhttps://string-db.org/network/1778262.MHIR_DE00204Putative peptidoglycan biosynthesis protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic [...]
CUX96530.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00205Hypothetical protein.
gltC protein networkhttps://string-db.org/network/1778262.MHIR_DE00206HTH-type transcriptional regulator GltC; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
rne protein networkhttps://string-db.org/network/1778262.MHIR_DE00210Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation [...]
rluC protein networkhttps://string-db.org/network/1778262.MHIR_DE00212Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
CUX96536.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00213Hypothetical protein.
CUX96537.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00214Hypothetical protein.
rpmF protein networkhttps://string-db.org/network/1778262.MHIR_DE0021550S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
CUX96539.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00216Hypothetical protein.
fabH protein networkhttps://string-db.org/network/1778262.MHIR_DE002173-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first c [...]
fabD protein networkhttps://string-db.org/network/1778262.MHIR_DE00218Malonyl CoA-acyl carrier protein transacylase.
fabG protein networkhttps://string-db.org/network/1778262.MHIR_DE002193-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongati [...]
acpP protein networkhttps://string-db.org/network/1778262.MHIR_DE00220Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
slyA protein networkhttps://string-db.org/network/1778262.MHIR_DE00222Transcriptional regulator SlyA; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.
slyB protein networkhttps://string-db.org/network/1778262.MHIR_DE00223Outer membrane lipoprotein SlyB precursor.
lpdA protein networkhttps://string-db.org/network/1778262.MHIR_DE00224Dihydrolipoyl dehydrogenase.
aceF protein networkhttps://string-db.org/network/1778262.MHIR_DE00225Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
aceE protein networkhttps://string-db.org/network/1778262.MHIR_DE00226Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
dnaX protein networkhttps://string-db.org/network/1778262.MHIR_DE00227DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuc [...]
ybaB protein networkhttps://string-db.org/network/1778262.MHIR_DE00228Nucleoid-associated protein YbaB; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
rlmB protein networkhttps://string-db.org/network/1778262.MHIR_DE0023423S rRNA (guanosine-2'-O-)-methyltransferase RlmB; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA me [...]
rnr protein networkhttps://string-db.org/network/1778262.MHIR_DE00235Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily.
hflC protein networkhttps://string-db.org/network/1778262.MHIR_DE00236Modulator of FtsH protease HflC; HflC and HflK could regulate a protease.
hflK protein networkhttps://string-db.org/network/1778262.MHIR_DE00237Modulator of FtsH protease HflK; HflC and HflK could encode or regulate a protease.
hfq protein networkhttps://string-db.org/network/1778262.MHIR_DE00238RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and chang [...]
miaA protein networkhttps://string-db.org/network/1778262.MHIR_DE00239tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(di [...]
amiB protein networkhttps://string-db.org/network/1778262.MHIR_DE00242N-acetylmuramoyl-L-alanine amidase AmiB precursor.
tsaE protein networkhttps://string-db.org/network/1778262.MHIR_DE00243tRNA threonylcarbamoyladenosine biosynthesis protein TsaE.
birA protein networkhttps://string-db.org/network/1778262.MHIR_DE00244Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5 [...]
murB protein networkhttps://string-db.org/network/1778262.MHIR_DE00245UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
rplU protein networkhttps://string-db.org/network/1778262.MHIR_DE0024650S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
ispF protein networkhttps://string-db.org/network/1778262.MHIR_DE002472-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
CUX96564.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00248Hypothetical protein.
rpsF protein networkhttps://string-db.org/network/1778262.MHIR_DE0024930S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
priB protein networkhttps://string-db.org/network/1778262.MHIR_DE00250Primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
rpsR protein networkhttps://string-db.org/network/1778262.MHIR_DE0025130S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
rplI protein networkhttps://string-db.org/network/1778262.MHIR_DE0025250S ribosomal protein L9; Binds to the 23S rRNA.
speG protein networkhttps://string-db.org/network/1778262.MHIR_DE00253Spermidine N(1)-acetyltransferase.
CUX96570.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00256HIT-like protein.
lpoB protein networkhttps://string-db.org/network/1778262.MHIR_DE00257Penicillin-binding protein activator LpoB precursor.
CUX96572.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00258Hypothetical protein.
infA protein networkhttps://string-db.org/network/1778262.MHIR_DE00259Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
yheH protein networkhttps://string-db.org/network/1778262.MHIR_DE00260Putative multidrug resistance ABC transporter ATP-binding/permease protein YheH.
cydD protein networkhttps://string-db.org/network/1778262.MHIR_DE00261ATP-binding/permease protein CydD.
pgl protein networkhttps://string-db.org/network/1778262.MHIR_DE002636-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.
ddlA protein networkhttps://string-db.org/network/1778262.MHIR_DE00264D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
mnmE protein networkhttps://string-db.org/network/1778262.MHIR_DE00266tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
CUX96581.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00267Hypothetical protein.
yidC protein networkhttps://string-db.org/network/1778262.MHIR_DE00268Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane pro [...]
rnpA protein networkhttps://string-db.org/network/1778262.MHIR_DE00269Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]
rpmH protein networkhttps://string-db.org/network/1778262.MHIR_DE0027050S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
tsaA protein networkhttps://string-db.org/network/1778262.MHIR_DE00271Putative peroxiredoxin.
clpB protein networkhttps://string-db.org/network/1778262.MHIR_DE00272Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to t [...]
rho protein networkhttps://string-db.org/network/1778262.MHIR_DE00274Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
trxA protein networkhttps://string-db.org/network/1778262.MHIR_DE00275Thioredoxin-1; Belongs to the thioredoxin family.
cvrA protein networkhttps://string-db.org/network/1778262.MHIR_DE00276K(+)/H(+) antiporter NhaP2; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the [...]
CUX96591.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00277Hypothetical protein.
yqjA protein networkhttps://string-db.org/network/1778262.MHIR_DE00279Inner membrane protein YqjA.
gltX protein networkhttps://string-db.org/network/1778262.MHIR_DE00284Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of [...]
tilS protein networkhttps://string-db.org/network/1778262.MHIR_DE00286tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is c [...]
pfkA protein networkhttps://string-db.org/network/1778262.MHIR_DE002876-phosphofructokinase isozyme 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
CUX96596.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00291Hypothetical protein.
CUX96597.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00292Hypothetical protein.
tldD protein networkhttps://string-db.org/network/1778262.MHIR_DE00293Protease TldD.
CUX96599.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00295Hypothetical protein.
rlmN protein networkhttps://string-db.org/network/1778262.MHIR_DE00296Dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial rol [...]
CUX96601.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00297Hypothetical protein.
rodZ protein networkhttps://string-db.org/network/1778262.MHIR_DE00298Cytoskeleton protein RodZ; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. Belongs to the RodZ family.
hisS protein networkhttps://string-db.org/network/1778262.MHIR_DE00299Histidine--tRNA ligase.
bamB protein networkhttps://string-db.org/network/1778262.MHIR_DE00300Outer membrane protein assembly factor BamB precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer memb [...]
lolB protein networkhttps://string-db.org/network/1778262.MHIR_DE00301Outer-membrane lipoprotein LolB precursor; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
prs protein networkhttps://string-db.org/network/1778262.MHIR_DE00302Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
pth protein networkhttps://string-db.org/network/1778262.MHIR_DE00303Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
ychF protein networkhttps://string-db.org/network/1778262.MHIR_DE00304Ribosome-binding ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
dsbB protein networkhttps://string-db.org/network/1778262.MHIR_DE00309Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
tpiA protein networkhttps://string-db.org/network/1778262.MHIR_DE00310Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
msbA protein networkhttps://string-db.org/network/1778262.MHIR_DE00313Lipid A export ATP-binding/permease protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) [...]
lpxK protein networkhttps://string-db.org/network/1778262.MHIR_DE00314Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis [...]
CUX96614.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00315Hypothetical protein.
accC protein networkhttps://string-db.org/network/1778262.MHIR_DE00316Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarbox [...]
aroQ_2 protein networkhttps://string-db.org/network/1778262.MHIR_DE003173-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
amiD protein networkhttps://string-db.org/network/1778262.MHIR_DE00318N-acetylmuramoyl-L-alanine amidase AmiD precursor.
tusE protein networkhttps://string-db.org/network/1778262.MHIR_DE00319Sulfurtransferase TusE; Part of a sulfur-relay system.
trpA protein networkhttps://string-db.org/network/1778262.MHIR_DE00320Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
trpB protein networkhttps://string-db.org/network/1778262.MHIR_DE00321Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpC protein networkhttps://string-db.org/network/1778262.MHIR_DE00322Tryptophan biosynthesis protein TrpCF.
trpGD protein networkhttps://string-db.org/network/1778262.MHIR_DE00323Bifunctional protein TrpGD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
trpG protein networkhttps://string-db.org/network/1778262.MHIR_DE00324Anthranilate synthase component 2.
trpE protein networkhttps://string-db.org/network/1778262.MHIR_DE00325Anthranilate synthase component 1.
carA protein networkhttps://string-db.org/network/1778262.MHIR_DE00326Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
carB protein networkhttps://string-db.org/network/1778262.MHIR_DE00327Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.
folA protein networkhttps://string-db.org/network/1778262.MHIR_DE00328Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
engB protein networkhttps://string-db.org/network/1778262.MHIR_DE00332Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. E [...]
ybgI protein networkhttps://string-db.org/network/1778262.MHIR_DE00333Putative GTP cyclohydrolase 1 type 2.
phoP_2 protein networkhttps://string-db.org/network/1778262.MHIR_DE00336Alkaline phosphatase synthesis transcriptional regulatory protein PhoP.
pykA protein networkhttps://string-db.org/network/1778262.MHIR_DE00337Pyruvate kinase II; Belongs to the pyruvate kinase family.
CUX96632.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00338Hypothetical protein.
CUX96633.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00339Hypothetical protein.
fabA protein networkhttps://string-db.org/network/1778262.MHIR_DE003403-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-deceno [...]
lon1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00341Lon protease 1.
rsmC protein networkhttps://string-db.org/network/1778262.MHIR_DE00345Ribosomal RNA small subunit methyltransferase C; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.
rnt protein networkhttps://string-db.org/network/1778262.MHIR_DE00346Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP [...]
dnaB protein networkhttps://string-db.org/network/1778262.MHIR_DE00347Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
ssb protein networkhttps://string-db.org/network/1778262.MHIR_DE00348Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of act [...]
lapB protein networkhttps://string-db.org/network/1778262.MHIR_DE00349Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity [...]
yciS protein networkhttps://string-db.org/network/1778262.MHIR_DE00350Inner membrane protein YciS.
pgpB protein networkhttps://string-db.org/network/1778262.MHIR_DE00351Phosphatidylglycerophosphatase B.
truA protein networkhttps://string-db.org/network/1778262.MHIR_DE00352tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
panC protein networkhttps://string-db.org/network/1778262.MHIR_DE00354Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
panB protein networkhttps://string-db.org/network/1778262.MHIR_DE003553-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to [...]
CUX96648.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00357Hypothetical protein.
CUX96649.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00358Hypothetical protein.
yebC protein networkhttps://string-db.org/network/1778262.MHIR_DE00361Putative transcriptional regulatory protein YebC.
ruvC protein networkhttps://string-db.org/network/1778262.MHIR_DE00362Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to st [...]
ruvA protein networkhttps://string-db.org/network/1778262.MHIR_DE00363Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may [...]
ruvB protein networkhttps://string-db.org/network/1778262.MHIR_DE00364Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may [...]
CUX96654.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00365Hypothetical protein.
CUX96655.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00366Hypothetical protein.
fpr protein networkhttps://string-db.org/network/1778262.MHIR_DE00367Ferredoxin--NADP reductase.
tusD protein networkhttps://string-db.org/network/1778262.MHIR_DE00370Sulfurtransferase TusD; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfer [...]
argS protein networkhttps://string-db.org/network/1778262.MHIR_DE00371Arginine--tRNA ligase.
dnaJ protein networkhttps://string-db.org/network/1778262.MHIR_DE00372Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an [...]
dnaK protein networkhttps://string-db.org/network/1778262.MHIR_DE00373Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
CUX96662.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00374Hypothetical protein.
ygfZ protein networkhttps://string-db.org/network/1778262.MHIR_DE00375tRNA-modifying protein YgfZ; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act [...]
glyQ_1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00376Glycine--tRNA ligase alpha subunit.
rpoC protein networkhttps://string-db.org/network/1778262.MHIR_DE00377DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/1778262.MHIR_DE00378DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/1778262.MHIR_DE0037950S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the ba [...]
rplJ protein networkhttps://string-db.org/network/1778262.MHIR_DE0038050S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
rplA protein networkhttps://string-db.org/network/1778262.MHIR_DE0038150S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/1778262.MHIR_DE0038250S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/1778262.MHIR_DE00383Transcription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elong [...]
secE protein networkhttps://string-db.org/network/1778262.MHIR_DE00384Protein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belon [...]
CUX96673.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00385Hypothetical protein.
tufA protein networkhttps://string-db.org/network/1778262.MHIR_DE00386Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
valS protein networkhttps://string-db.org/network/1778262.MHIR_DE00393Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, [...]
lptF protein networkhttps://string-db.org/network/1778262.MHIR_DE00395Lipopolysaccharide export system permease protein LptF.
lptG protein networkhttps://string-db.org/network/1778262.MHIR_DE00396Lipopolysaccharide export system permease protein LptG.
glyS protein networkhttps://string-db.org/network/1778262.MHIR_DE00397Glycine--tRNA ligase beta subunit.
envC protein networkhttps://string-db.org/network/1778262.MHIR_DE00402Murein hydrolase activator EnvC precursor.
pitA protein networkhttps://string-db.org/network/1778262.MHIR_DE00403Low-affinity inorganic phosphate transporter 1.
cydX protein networkhttps://string-db.org/network/1778262.MHIR_DE00404Cytochrome bd-I ubiquinol oxidase subunit X.
cydB protein networkhttps://string-db.org/network/1778262.MHIR_DE00405Cytochrome bd-I ubiquinol oxidase subunit 2.
cydA protein networkhttps://string-db.org/network/1778262.MHIR_DE00406Cytochrome bd-I ubiquinol oxidase subunit 1.
gapA_1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00407Glyceraldehyde-3-phosphate dehydrogenase A; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
groS protein networkhttps://string-db.org/network/1778262.MHIR_DE0041110 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
groL protein networkhttps://string-db.org/network/1778262.MHIR_DE0041260 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
efp protein networkhttps://string-db.org/network/1778262.MHIR_DE00413Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by [...]
secB protein networkhttps://string-db.org/network/1778262.MHIR_DE00415Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, [...]
glpE protein networkhttps://string-db.org/network/1778262.MHIR_DE00416Thiosulfate sulfurtransferase GlpE.
gyrA protein networkhttps://string-db.org/network/1778262.MHIR_DE00417DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
nrdA protein networkhttps://string-db.org/network/1778262.MHIR_DE00418Ribonucleoside-diphosphate reductase 1 subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotide [...]
nrdB protein networkhttps://string-db.org/network/1778262.MHIR_DE00419Ribonucleoside-diphosphate reductase 1 subunit beta.
kdsA protein networkhttps://string-db.org/network/1778262.MHIR_DE004202-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family.
CUX96696.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00421Hypothetical protein.
iscA protein networkhttps://string-db.org/network/1778262.MHIR_DE00422Iron-binding protein IscA; Belongs to the HesB/IscA family.
sufB protein networkhttps://string-db.org/network/1778262.MHIR_DE00423FeS cluster assembly protein SufB.
sufC protein networkhttps://string-db.org/network/1778262.MHIR_DE00424Putative ATP-dependent transporter SufC.
sufD protein networkhttps://string-db.org/network/1778262.MHIR_DE00425FeS cluster assembly protein SufD.
sufS protein networkhttps://string-db.org/network/1778262.MHIR_DE00426Cysteine desulfurase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomo [...]
sufE protein networkhttps://string-db.org/network/1778262.MHIR_DE00427Cysteine desulfuration protein SufE; Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L- alanine and constitutes an essent [...]
lpp protein networkhttps://string-db.org/network/1778262.MHIR_DE00428Major outer membrane lipoprotein Lpp precursor.
thyA protein networkhttps://string-db.org/network/1778262.MHIR_DE00431Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...]
lgt protein networkhttps://string-db.org/network/1778262.MHIR_DE00432Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
grxD protein networkhttps://string-db.org/network/1778262.MHIR_DE00434Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily.
tsaD protein networkhttps://string-db.org/network/1778262.MHIR_DE00435tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is [...]
hns protein networkhttps://string-db.org/network/1778262.MHIR_DE00436DNA-binding protein H-NS; Belongs to the histone-like protein H-NS family.
ybeY protein networkhttps://string-db.org/network/1778262.MHIR_DE00437Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
lnt protein networkhttps://string-db.org/network/1778262.MHIR_DE00438Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrol [...]
uvrD protein networkhttps://string-db.org/network/1778262.MHIR_DE00439DNA helicase II.
zur protein networkhttps://string-db.org/network/1778262.MHIR_DE00440Zinc uptake regulation protein; Belongs to the Fur family.
mntH protein networkhttps://string-db.org/network/1778262.MHIR_DE00445Divalent metal cation transporter MntH; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
mepM protein networkhttps://string-db.org/network/1778262.MHIR_DE00446Murein DD-endopeptidase MepM.
plsB protein networkhttps://string-db.org/network/1778262.MHIR_DE00447Glycerol-3-phosphate acyltransferase; Belongs to the GPAT/DAPAT family.
lexA protein networkhttps://string-db.org/network/1778262.MHIR_DE00448LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response).
CUX96718.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00449Hypothetical protein.
obgE protein networkhttps://string-db.org/network/1778262.MHIR_DE00450GTPase ObgE/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in [...]
rppH protein networkhttps://string-db.org/network/1778262.MHIR_DE00452RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can [...]
ycfH protein networkhttps://string-db.org/network/1778262.MHIR_DE00453Putative deoxyribonuclease YcfH.
holB protein networkhttps://string-db.org/network/1778262.MHIR_DE00454DNA polymerase III subunit delta'.
tmk protein networkhttps://string-db.org/network/1778262.MHIR_DE00455Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
psd protein networkhttps://string-db.org/network/1778262.MHIR_DE00457Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
recC protein networkhttps://string-db.org/network/1778262.MHIR_DE00463RecBCD enzyme subunit RecC; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidi [...]
recB protein networkhttps://string-db.org/network/1778262.MHIR_DE00464RecBCD enzyme subunit RecB; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidi [...]
serS protein networkhttps://string-db.org/network/1778262.MHIR_DE00465Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further co [...]
lolA protein networkhttps://string-db.org/network/1778262.MHIR_DE00466Outer-membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if t [...]
secG protein networkhttps://string-db.org/network/1778262.MHIR_DE00469Protein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
bamD protein networkhttps://string-db.org/network/1778262.MHIR_DE00470Outer membrane protein assembly factor BamD precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer memb [...]
rluD protein networkhttps://string-db.org/network/1778262.MHIR_DE00471Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
cspC protein networkhttps://string-db.org/network/1778262.MHIR_DE00474Cold shock-like protein CspC.
recA protein networkhttps://string-db.org/network/1778262.MHIR_DE00475Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of hom [...]
CUX96734.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00476Hypothetical protein.
accD protein networkhttps://string-db.org/network/1778262.MHIR_DE00477Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its [...]
CUX96736.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00479Hypothetical protein; Belongs to the UPF0270 family.
CUX96737.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00480Hypothetical protein.
glnS protein networkhttps://string-db.org/network/1778262.MHIR_DE00481Glutamine--tRNA ligase.
CUX96739.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00482Hypothetical protein; Belongs to the UPF0434 family.
kdsB protein networkhttps://string-db.org/network/1778262.MHIR_DE004833-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
tadA protein networkhttps://string-db.org/network/1778262.MHIR_DE00484tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
CUX96742.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00485Hypothetical protein.
CUX96743.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00486Hypothetical protein.
ndhC protein networkhttps://string-db.org/network/1778262.MHIR_DE00488NAD(P)H-quinone oxidoreductase subunit 3; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the [...]
nuoB protein networkhttps://string-db.org/network/1778262.MHIR_DE00489NADH-quinone oxidoreductase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoC protein networkhttps://string-db.org/network/1778262.MHIR_DE00490NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the [...]
nuoE protein networkhttps://string-db.org/network/1778262.MHIR_DE00491NADH-quinone oxidoreductase subunit E.
nuoF protein networkhttps://string-db.org/network/1778262.MHIR_DE00492NADH-quinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit fa [...]
nuoG protein networkhttps://string-db.org/network/1778262.MHIR_DE00493NADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton trans [...]
nuoH protein networkhttps://string-db.org/network/1778262.MHIR_DE00494NADH-quinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoI protein networkhttps://string-db.org/network/1778262.MHIR_DE00495NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoJ protein networkhttps://string-db.org/network/1778262.MHIR_DE00496NADH-quinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton trans [...]
nuoK protein networkhttps://string-db.org/network/1778262.MHIR_DE00497NADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoL protein networkhttps://string-db.org/network/1778262.MHIR_DE00498NADH-quinone oxidoreductase subunit L.
nuoM protein networkhttps://string-db.org/network/1778262.MHIR_DE00499NADH-quinone oxidoreductase subunit M.
nuoN protein networkhttps://string-db.org/network/1778262.MHIR_DE00500NADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
aspS protein networkhttps://string-db.org/network/1778262.MHIR_DE00501Aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor en [...]
rpoH protein networkhttps://string-db.org/network/1778262.MHIR_DE00502RNA polymerase sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is invol [...]
ftsY protein networkhttps://string-db.org/network/1778262.MHIR_DE00506Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal [...]
rsmD protein networkhttps://string-db.org/network/1778262.MHIR_DE00507Ribosomal RNA small subunit methyltransferase D; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD [...]
CUX96761.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00508Hypothetical protein.
tusA protein networkhttps://string-db.org/network/1778262.MHIR_DE00509Sulfurtransferase TusA; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modifie [...]
ackA protein networkhttps://string-db.org/network/1778262.MHIR_DE00510Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
pta protein networkhttps://string-db.org/network/1778262.MHIR_DE00511Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
topA protein networkhttps://string-db.org/network/1778262.MHIR_DE00512DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of [...]
dcd protein networkhttps://string-db.org/network/1778262.MHIR_DE00513Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
CUX96767.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00514Hypothetical protein; Belongs to the UPF0250 family.
lipB protein networkhttps://string-db.org/network/1778262.MHIR_DE00515Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also ac [...]
lipA protein networkhttps://string-db.org/network/1778262.MHIR_DE00516Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, there [...]
ribC protein networkhttps://string-db.org/network/1778262.MHIR_DE00517Riboflavin synthase.
lolE protein networkhttps://string-db.org/network/1778262.MHIR_DE00518Lipoprotein-releasing system transmembrane protein LolE.
lolD protein networkhttps://string-db.org/network/1778262.MHIR_DE00519Lipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
lolC protein networkhttps://string-db.org/network/1778262.MHIR_DE00520Lipoprotein-releasing system transmembrane protein LolC.
mfd protein networkhttps://string-db.org/network/1778262.MHIR_DE00521Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated tr [...]
orn protein networkhttps://string-db.org/network/1778262.MHIR_DE00522Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
osmY protein networkhttps://string-db.org/network/1778262.MHIR_DE00524Osmotically-inducible protein Y precursor.
rsmI protein networkhttps://string-db.org/network/1778262.MHIR_DE00525Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
atpH protein networkhttps://string-db.org/network/1778262.MHIR_DE00531ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extra [...]
atpC protein networkhttps://string-db.org/network/1778262.MHIR_DE00537ATP synthase epsilon chain.
parE protein networkhttps://string-db.org/network/1778262.MHIR_DE00539DNA topoisomerase 4 subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular [...]
der protein networkhttps://string-db.org/network/1778262.MHIR_DE00541GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
hemG protein networkhttps://string-db.org/network/1778262.MHIR_DE00542Protoporphyrinogen IX dehydrogenase [menaquinone].
fbaA protein networkhttps://string-db.org/network/1778262.MHIR_DE00543Fructose-bisphosphate aldolase class 2; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bis [...]
pgk protein networkhttps://string-db.org/network/1778262.MHIR_DE00544Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
hspQ protein networkhttps://string-db.org/network/1778262.MHIR_DE00545Heat shock protein HspQ; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.
fis protein networkhttps://string-db.org/network/1778262.MHIR_DE00547DNA-binding protein Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.
mnmG protein networkhttps://string-db.org/network/1778262.MHIR_DE00548tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
pgi protein networkhttps://string-db.org/network/1778262.MHIR_DE00549Glucose-6-phosphate isomerase; Belongs to the GPI family.
pgsA protein networkhttps://string-db.org/network/1778262.MHIR_DE00551CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyl [...]
ibpA protein networkhttps://string-db.org/network/1778262.MHIR_DE00552Small heat shock protein IbpA; Belongs to the small heat shock protein (HSP20) family.
CUX96796.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00554Putative periplasmic iron-binding protein precursor; Belongs to the bacterial solute-binding protein 9 family.
mntB protein networkhttps://string-db.org/network/1778262.MHIR_DE00555Manganese transport system membrane protein MntB.
fhuC protein networkhttps://string-db.org/network/1778262.MHIR_DE00556Iron(3+)-hydroxamate import ATP-binding protein FhuC.
CUX96799.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00557Hypothetical protein.
CUX96800.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00558Hypothetical protein.
yciB protein networkhttps://string-db.org/network/1778262.MHIR_DE00559Intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
gpmA protein networkhttps://string-db.org/network/1778262.MHIR_DE005602,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- depende [...]
rplQ protein networkhttps://string-db.org/network/1778262.MHIR_DE0056150S ribosomal protein L17.
rpoA protein networkhttps://string-db.org/network/1778262.MHIR_DE00562DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpsD protein networkhttps://string-db.org/network/1778262.MHIR_DE0056330S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpsK protein networkhttps://string-db.org/network/1778262.MHIR_DE0056430S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsM protein networkhttps://string-db.org/network/1778262.MHIR_DE0056530S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpmJ protein networkhttps://string-db.org/network/1778262.MHIR_DE0056750S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
secY protein networkhttps://string-db.org/network/1778262.MHIR_DE00568Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the [...]
rplO protein networkhttps://string-db.org/network/1778262.MHIR_DE0056950S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
rpmD protein networkhttps://string-db.org/network/1778262.MHIR_DE0057050S ribosomal protein L30.
rpsE protein networkhttps://string-db.org/network/1778262.MHIR_DE0057130S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 fam [...]
rplR protein networkhttps://string-db.org/network/1778262.MHIR_DE0057250S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
rplF protein networkhttps://string-db.org/network/1778262.MHIR_DE0057350S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rpsH protein networkhttps://string-db.org/network/1778262.MHIR_DE0057430S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to [...]
rpsN protein networkhttps://string-db.org/network/1778262.MHIR_DE0057530S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the un [...]
rplE protein networkhttps://string-db.org/network/1778262.MHIR_DE0057650S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rplX protein networkhttps://string-db.org/network/1778262.MHIR_DE0057750S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplN protein networkhttps://string-db.org/network/1778262.MHIR_DE0057850S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rpsQ protein networkhttps://string-db.org/network/1778262.MHIR_DE0057930S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rpmC protein networkhttps://string-db.org/network/1778262.MHIR_DE0058050S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
rplP protein networkhttps://string-db.org/network/1778262.MHIR_DE0058150S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsC protein networkhttps://string-db.org/network/1778262.MHIR_DE0058230S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplV protein networkhttps://string-db.org/network/1778262.MHIR_DE0058350S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wal [...]
rpsS protein networkhttps://string-db.org/network/1778262.MHIR_DE0058430S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplB protein networkhttps://string-db.org/network/1778262.MHIR_DE0058550S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rplW protein networkhttps://string-db.org/network/1778262.MHIR_DE0058650S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplD protein networkhttps://string-db.org/network/1778262.MHIR_DE0058750S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
rplC protein networkhttps://string-db.org/network/1778262.MHIR_DE0058850S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rpsJ protein networkhttps://string-db.org/network/1778262.MHIR_DE0058930S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
tamA protein networkhttps://string-db.org/network/1778262.MHIR_DE00590Translocation and assembly module TamA precursor.
tamB protein networkhttps://string-db.org/network/1778262.MHIR_DE00591Translocation and assembly module TamB.
polA protein networkhttps://string-db.org/network/1778262.MHIR_DE00592DNA polymerase I.
ppa protein networkhttps://string-db.org/network/1778262.MHIR_DE00593Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
adk protein networkhttps://string-db.org/network/1778262.MHIR_DE00596Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
hemH protein networkhttps://string-db.org/network/1778262.MHIR_DE00597Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
rpmA protein networkhttps://string-db.org/network/1778262.MHIR_DE0059850S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
cls protein networkhttps://string-db.org/network/1778262.MHIR_DE00599Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
trxB protein networkhttps://string-db.org/network/1778262.MHIR_DE00600Thioredoxin reductase.
waaA protein networkhttps://string-db.org/network/1778262.MHIR_DE006013-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV( [...]
htrB protein networkhttps://string-db.org/network/1778262.MHIR_DE00602Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
rplY protein networkhttps://string-db.org/network/1778262.MHIR_DE0060550S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
prmC protein networkhttps://string-db.org/network/1778262.MHIR_DE00606Release factor glutamine methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; B [...]
prfA protein networkhttps://string-db.org/network/1778262.MHIR_DE00607Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
fnr protein networkhttps://string-db.org/network/1778262.MHIR_DE00608Fumarate and nitrate reduction regulatory protein.
gyrB protein networkhttps://string-db.org/network/1778262.MHIR_DE00610DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
dnaN protein networkhttps://string-db.org/network/1778262.MHIR_DE00611DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadin [...]
dnaA protein networkhttps://string-db.org/network/1778262.MHIR_DE00612Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically doub [...]
CUX96852.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00613YGGT family protein.
hemN protein networkhttps://string-db.org/network/1778262.MHIR_DE00614Oxygen-independent coproporphyrinogen-III oxidase 1; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Bind [...]
yqgF protein networkhttps://string-db.org/network/1778262.MHIR_DE00615Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
folD protein networkhttps://string-db.org/network/1778262.MHIR_DE00617Bifunctional protein FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formy [...]
cysS protein networkhttps://string-db.org/network/1778262.MHIR_DE00618Cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
CUX96857.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00619Hypothetical protein.
lpxH protein networkhttps://string-db.org/network/1778262.MHIR_DE00620UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water [...]
CUX96859.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00621Hypothetical protein.
purE protein networkhttps://string-db.org/network/1778262.MHIR_DE00623N5-carboxyaminoimidazole ribonucleotide mutase.
rpsU protein networkhttps://string-db.org/network/1778262.MHIR_DE0062430S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
dnaG protein networkhttps://string-db.org/network/1778262.MHIR_DE00625DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpoD protein networkhttps://string-db.org/network/1778262.MHIR_DE00626RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the p [...]
dut protein networkhttps://string-db.org/network/1778262.MHIR_DE00627Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intrace [...]
fabB protein networkhttps://string-db.org/network/1778262.MHIR_DE006283-oxoacyl-[acyl-carrier-protein] synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
asnS protein networkhttps://string-db.org/network/1778262.MHIR_DE00630Asparagine--tRNA ligase.
aroK protein networkhttps://string-db.org/network/1778262.MHIR_DE00632Shikimate kinase 1; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
rpe protein networkhttps://string-db.org/network/1778262.MHIR_DE00633Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
CUX96870.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00634Hypothetical protein.
trpS protein networkhttps://string-db.org/network/1778262.MHIR_DE00635Tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
acpS protein networkhttps://string-db.org/network/1778262.MHIR_DE00637Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
CUX96873.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00638Hypothetical protein.
mlaA protein networkhttps://string-db.org/network/1778262.MHIR_DE00639Putative phospholipid-binding lipoprotein MlaA precursor.
gnd protein networkhttps://string-db.org/network/1778262.MHIR_DE006406-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
fusA protein networkhttps://string-db.org/network/1778262.MHIR_DE00641Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
rpsG protein networkhttps://string-db.org/network/1778262.MHIR_DE0064230S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
rpsL protein networkhttps://string-db.org/network/1778262.MHIR_DE0064330S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S an [...]
tusB protein networkhttps://string-db.org/network/1778262.MHIR_DE00644Protein TusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
dsrF protein networkhttps://string-db.org/network/1778262.MHIR_DE00645Intracellular sulfur oxidation protein DsrF; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
pcnB protein networkhttps://string-db.org/network/1778262.MHIR_DE00647Poly(A) polymerase I precursor; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, throug [...]
dksA protein networkhttps://string-db.org/network/1778262.MHIR_DE00648RNA polymerase-binding transcription factor DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive [...]
CUX96883.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00649Hypothetical protein.
mrcB protein networkhttps://string-db.org/network/1778262.MHIR_DE00650Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domai [...]
dapB protein networkhttps://string-db.org/network/1778262.MHIR_DE006524-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
CUX96887.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00654Hypothetical protein.
mutY protein networkhttps://string-db.org/network/1778262.MHIR_DE00655A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
trmB protein networkhttps://string-db.org/network/1778262.MHIR_DE00656tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB f [...]
mhqR protein networkhttps://string-db.org/network/1778262.MHIR_DE00657HTH-type transcriptional regulator MhqR.
ybiS protein networkhttps://string-db.org/network/1778262.MHIR_DE00658Putative L,D-transpeptidase YbiS precursor.
ligA protein networkhttps://string-db.org/network/1778262.MHIR_DE00659DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sourc [...]
bamE protein networkhttps://string-db.org/network/1778262.MHIR_DE00660Outer membrane protein assembly factor BamE precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer memb [...]
CUX96894.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00663Hypothetical protein.
grpE protein networkhttps://string-db.org/network/1778262.MHIR_DE00664Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleot [...]
CUX96896.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00665Hypothetical protein.
deaD protein networkhttps://string-db.org/network/1778262.MHIR_DE00666ATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
pnp protein networkhttps://string-db.org/network/1778262.MHIR_DE00667Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
rpsO protein networkhttps://string-db.org/network/1778262.MHIR_DE0066930S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
truB protein networkhttps://string-db.org/network/1778262.MHIR_DE00671tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
rbfA protein networkhttps://string-db.org/network/1778262.MHIR_DE00672Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
infB protein networkhttps://string-db.org/network/1778262.MHIR_DE00673Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
nusA protein networkhttps://string-db.org/network/1778262.MHIR_DE00674Transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination.
mdtK protein networkhttps://string-db.org/network/1778262.MHIR_DE00675Multidrug resistance protein MdtK.
CUX96905.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00676Hypothetical protein.
nth protein networkhttps://string-db.org/network/1778262.MHIR_DE00677Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- [...]
fabR protein networkhttps://string-db.org/network/1778262.MHIR_DE00678HTH-type transcriptional repressor FabR.
minC protein networkhttps://string-db.org/network/1778262.MHIR_DE00680Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments tha [...]
minD protein networkhttps://string-db.org/network/1778262.MHIR_DE00681Septum site-determining protein MinD.
minE protein networkhttps://string-db.org/network/1778262.MHIR_DE00682Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures c [...]
rpsA protein networkhttps://string-db.org/network/1778262.MHIR_DE0068330S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
cmk protein networkhttps://string-db.org/network/1778262.MHIR_DE00684Cytidylate kinase.
zapD protein networkhttps://string-db.org/network/1778262.MHIR_DE00685Cell division protein ZapD; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activ [...]
yacG protein networkhttps://string-db.org/network/1778262.MHIR_DE00686DNA gyrase inhibitor YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably d [...]
map protein networkhttps://string-db.org/network/1778262.MHIR_DE00688Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
CUX96917.1 protein networkhttps://string-db.org/network/1778262.MHIR_DE00689Hypothetical protein.
rpsB protein networkhttps://string-db.org/network/1778262.MHIR_DE0069130S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/1778262.MHIR_DE00692Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
frr protein networkhttps://string-db.org/network/1778262.MHIR_DE00693Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
pyrH protein networkhttps://string-db.org/network/1778262.MHIR_DE00694Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
ispU protein networkhttps://string-db.org/network/1778262.MHIR_DE00695Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate [...]
cdsA protein networkhttps://string-db.org/network/1778262.MHIR_DE00696Phosphatidate cytidylyltransferase; Belongs to the CDS family.
bamA protein networkhttps://string-db.org/network/1778262.MHIR_DE00697Outer membrane protein assembly factor BamA precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer memb [...]
skp protein networkhttps://string-db.org/network/1778262.MHIR_DE00698Chaperone protein Skp precursor; Belongs to the skp family.
lpxD protein networkhttps://string-db.org/network/1778262.MHIR_DE00699UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved [...]
fabZ protein networkhttps://string-db.org/network/1778262.MHIR_DE007003-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated an [...]
lpxA protein networkhttps://string-db.org/network/1778262.MHIR_DE00701Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer memb [...]
lpxB protein networkhttps://string-db.org/network/1778262.MHIR_DE00702Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid t [...]
dnaE protein networkhttps://string-db.org/network/1778262.MHIR_DE00703DNA polymerase III subunit alpha.
accA protein networkhttps://string-db.org/network/1778262.MHIR_DE00704Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on [...]
ptsN protein networkhttps://string-db.org/network/1778262.MHIR_DE00722Nitrogen regulatory protein.