Organism Overview: Walczuchella monophlebidarum


 
gidA protein networkhttps://string-db.org/network/1415657.FNIIJ_001tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
ybeY protein networkhttps://string-db.org/network/1415657.FNIIJ_002Metalloprotein, YbeY/ UPF0054family; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
korB protein networkhttps://string-db.org/network/1415657.FNIIJ_0042-oxoglutarate:ferredoxin oxidoreductase subunit beta.
ileS protein networkhttps://string-db.org/network/1415657.FNIIJ_007isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
yeaZ protein networkhttps://string-db.org/network/1415657.FNIIJ_008Peptidase M22.
prs protein networkhttps://string-db.org/network/1415657.FNIIJ_010Ribose-phosphate pyrophosphokinase.
rplY protein networkhttps://string-db.org/network/1415657.FNIIJ_01150S ribosomal protein L25, Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal prote [...]
engA protein networkhttps://string-db.org/network/1415657.FNIIJ_012Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA [...]
hflX protein networkhttps://string-db.org/network/1415657.FNIIJ_013GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPa [...]
ccoI protein networkhttps://string-db.org/network/1415657.FNIIJ_014Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase.
ccoS protein networkhttps://string-db.org/network/1415657.FNIIJ_015Putative cytochrome cbb3 oxidase maturation protein CcoS.
ccoNO protein networkhttps://string-db.org/network/1415657.FNIIJ_016Cbb3-type cytochrome c oxidase subunits CcoN/CcoO; Belongs to the heme-copper respiratory oxidase family.
ccoP protein networkhttps://string-db.org/network/1415657.FNIIJ_017Cbb3-type cytochrome c oxidase ccoP subunit III.
ccoH protein networkhttps://string-db.org/network/1415657.FNIIJ_018Cytochrome cbb3 oxidase maturation protein CcoH.
korA protein networkhttps://string-db.org/network/1415657.FNIIJ_0192-oxoglutarate ferredoxin oxidoreductase subunit alpha.
glnS protein networkhttps://string-db.org/network/1415657.FNIIJ_020glutaminyl-tRNA synthetase.
ykpA protein networkhttps://string-db.org/network/1415657.FNIIJ_022ABC transporter, ATP-binding protein.
smpB protein networkhttps://string-db.org/network/1415657.FNIIJ_023SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
tatC protein networkhttps://string-db.org/network/1415657.FNIIJ_024tatC: twin arginine-targeting protein translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in t [...]
FNIIJ_025 protein networkhttps://string-db.org/network/1415657.FNIIJ_025Hypothetical protein.
rpmG protein networkhttps://string-db.org/network/1415657.FNIIJ_02650S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/1415657.FNIIJ_02750S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
yidC protein networkhttps://string-db.org/network/1415657.FNIIJ_028Inner membrane protein translocase component YidC.
ftsH protein networkhttps://string-db.org/network/1415657.FNIIJ_029AAA-metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; [...]
dnaK protein networkhttps://string-db.org/network/1415657.FNIIJ_030Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
rplM protein networkhttps://string-db.org/network/1415657.FNIIJ_03150S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
rpsI protein networkhttps://string-db.org/network/1415657.FNIIJ_03230S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
rpsB protein networkhttps://string-db.org/network/1415657.FNIIJ_03330S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/1415657.FNIIJ_034Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
rpsL protein networkhttps://string-db.org/network/1415657.FNIIJ_036Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50 [...]
rpsG protein networkhttps://string-db.org/network/1415657.FNIIJ_037Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interfac [...]
fusA protein networkhttps://string-db.org/network/1415657.FNIIJ_038Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) [...]
rpsJ protein networkhttps://string-db.org/network/1415657.FNIIJ_03930S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rplC protein networkhttps://string-db.org/network/1415657.FNIIJ_04050S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal rib [...]
rplD protein networkhttps://string-db.org/network/1415657.FNIIJ_04150S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
rplW protein networkhttps://string-db.org/network/1415657.FNIIJ_04250S ribosomal protein L23.
rplB protein networkhttps://string-db.org/network/1415657.FNIIJ_04350S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rpsS protein networkhttps://string-db.org/network/1415657.FNIIJ_04450S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplV protein networkhttps://string-db.org/network/1415657.FNIIJ_045Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of [...]
rpsC protein networkhttps://string-db.org/network/1415657.FNIIJ_046Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplP protein networkhttps://string-db.org/network/1415657.FNIIJ_047Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsQ protein networkhttps://string-db.org/network/1415657.FNIIJ_04830S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rplN protein networkhttps://string-db.org/network/1415657.FNIIJ_049Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rplX protein networkhttps://string-db.org/network/1415657.FNIIJ_050Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplE protein networkhttps://string-db.org/network/1415657.FNIIJ_051Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In [...]
rpsN protein networkhttps://string-db.org/network/1415657.FNIIJ_052Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the univer [...]
rpsH protein networkhttps://string-db.org/network/1415657.FNIIJ_053Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the [...]
rplF protein networkhttps://string-db.org/network/1415657.FNIIJ_054Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA [...]
rplR protein networkhttps://string-db.org/network/1415657.FNIIJ_055Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
rpsE protein networkhttps://string-db.org/network/1415657.FNIIJ_056Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
rpmD protein networkhttps://string-db.org/network/1415657.FNIIJ_057Ribosomal protein L30.
rplO protein networkhttps://string-db.org/network/1415657.FNIIJ_058Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
secY protein networkhttps://string-db.org/network/1415657.FNIIJ_059Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at [...]
infA protein networkhttps://string-db.org/network/1415657.FNIIJ_060Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
rpmJ protein networkhttps://string-db.org/network/1415657.FNIIJ_061Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
rpsM protein networkhttps://string-db.org/network/1415657.FNIIJ_06230S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpsK protein networkhttps://string-db.org/network/1415657.FNIIJ_06330S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsD protein networkhttps://string-db.org/network/1415657.FNIIJ_064Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpoA protein networkhttps://string-db.org/network/1415657.FNIIJ_065DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
FNIIJ_066 protein networkhttps://string-db.org/network/1415657.FNIIJ_066Hypothetical protein.
rplQ protein networkhttps://string-db.org/network/1415657.FNIIJ_067Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.
valS protein networkhttps://string-db.org/network/1415657.FNIIJ_068valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
argS protein networkhttps://string-db.org/network/1415657.FNIIJ_069arginyl-tRNA synthetase.
thrS protein networkhttps://string-db.org/network/1415657.FNIIJ_071threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor en [...]
infC protein networkhttps://string-db.org/network/1415657.FNIIJ_072Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
rpmI protein networkhttps://string-db.org/network/1415657.FNIIJ_073Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
rplT protein networkhttps://string-db.org/network/1415657.FNIIJ_074Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing function [...]
def protein networkhttps://string-db.org/network/1415657.FNIIJ_075Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
yqgF protein networkhttps://string-db.org/network/1415657.FNIIJ_076Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
dapD protein networkhttps://string-db.org/network/1415657.FNIIJ_0772,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
lipA protein networkhttps://string-db.org/network/1415657.FNIIJ_079Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, there [...]
FNIIJ_080 protein networkhttps://string-db.org/network/1415657.FNIIJ_080Hypothetical protein.
trmU protein networkhttps://string-db.org/network/1415657.FNIIJ_081tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
dnaJ protein networkhttps://string-db.org/network/1415657.FNIIJ_082HSP40 chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonom [...]
grpE protein networkhttps://string-db.org/network/1415657.FNIIJ_083GrpE protein (HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. [...]
lpdA protein networkhttps://string-db.org/network/1415657.FNIIJ_084Dihydrolipoamide dehydrogenase.
aroK protein networkhttps://string-db.org/network/1415657.FNIIJ_087Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
tilS protein networkhttps://string-db.org/network/1415657.FNIIJ_088tRNAIle-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is c [...]
tatA protein networkhttps://string-db.org/network/1415657.FNIIJ_091Putative Sec-independent-protein-translocase protein TatA/E.
rpsA protein networkhttps://string-db.org/network/1415657.FNIIJ_092Ribosomal protein S1.
gyrA protein networkhttps://string-db.org/network/1415657.FNIIJ_093DNA gyrase A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
aroB protein networkhttps://string-db.org/network/1415657.FNIIJ_0943-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
ndh protein networkhttps://string-db.org/network/1415657.FNIIJ_095NADH dehydrogenase.
aroC protein networkhttps://string-db.org/network/1415657.FNIIJ_096Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
miaA protein networkhttps://string-db.org/network/1415657.FNIIJ_097tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(di [...]
htpG protein networkhttps://string-db.org/network/1415657.FNIIJ_098Heat shock protein 90; Molecular chaperone. Has ATPase activity.
rpmH protein networkhttps://string-db.org/network/1415657.FNIIJ_099Ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
efp protein networkhttps://string-db.org/network/1415657.FNIIJ_100Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functi [...]
sucD protein networkhttps://string-db.org/network/1415657.FNIIJ_101succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus re [...]
ahpC protein networkhttps://string-db.org/network/1415657.FNIIJ_102Alkyl hydroperoxide reductase subunit C.
FNIIJ_103 protein networkhttps://string-db.org/network/1415657.FNIIJ_103MiaB-like tRNA modifying protein.
pfkA protein networkhttps://string-db.org/network/1415657.FNIIJ_1046-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
holA protein networkhttps://string-db.org/network/1415657.FNIIJ_105DNA polymerase III delta subunit.
dnaE/dnaQ protein networkhttps://string-db.org/network/1415657.FNIIJ_109Putative DNA polymerase III, alpha subunit (dnaE)/DNA polymerase III, epsilon subunit (dnaQ) fusion protein.
argGA protein networkhttps://string-db.org/network/1415657.FNIIJ_110Bifunctional argininosuccinate synthase/acetyltransferase activity of N-acetylglutamate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
argC protein networkhttps://string-db.org/network/1415657.FNIIJ_111N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydroge [...]
carA protein networkhttps://string-db.org/network/1415657.FNIIJ_113Carbamoyl phosphate synthase small subunit; Belongs to the CarA family.
argB protein networkhttps://string-db.org/network/1415657.FNIIJ_116Acetylglutamate kinase.
thrA protein networkhttps://string-db.org/network/1415657.FNIIJ_118Bifunctional aspartokinase/homoserine dehydrogenase.
thrB protein networkhttps://string-db.org/network/1415657.FNIIJ_119Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
thrC protein networkhttps://string-db.org/network/1415657.FNIIJ_120Threonine synthase.
clpB protein networkhttps://string-db.org/network/1415657.FNIIJ_121Heat shock ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to [...]
prfB protein networkhttps://string-db.org/network/1415657.FNIIJ_122Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
secA protein networkhttps://string-db.org/network/1415657.FNIIJ_123Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to [...]
FNIIJ_124 protein networkhttps://string-db.org/network/1415657.FNIIJ_124Hypothetical protein.
metE protein networkhttps://string-db.org/network/1415657.FNIIJ_125Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 indepe [...]
fmt protein networkhttps://string-db.org/network/1415657.FNIIJ_126methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
dnaN protein networkhttps://string-db.org/network/1415657.FNIIJ_128DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadi [...]
pheT protein networkhttps://string-db.org/network/1415657.FNIIJ_129phenylalanyl-tRNA synthetase subunit beta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
obg protein networkhttps://string-db.org/network/1415657.FNIIJ_130GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Play [...]
dapA protein networkhttps://string-db.org/network/1415657.FNIIJ_132Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
FNIIJ_133 protein networkhttps://string-db.org/network/1415657.FNIIJ_133Hypothetical protein.
lipB protein networkhttps://string-db.org/network/1415657.FNIIJ_135Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can al [...]
rplS protein networkhttps://string-db.org/network/1415657.FNIIJ_136Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
lon protein networkhttps://string-db.org/network/1415657.FNIIJ_138ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for [...]
lysA protein networkhttps://string-db.org/network/1415657.FNIIJ_139Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
FNIIJ_143 protein networkhttps://string-db.org/network/1415657.FNIIJ_143PcrA-like UvrD/Rep family ATP-dependent DNA helicase.
ilvC protein networkhttps://string-db.org/network/1415657.FNIIJ_144Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
ilvB protein networkhttps://string-db.org/network/1415657.FNIIJ_146Acetolactate synthase large subunit.
ilvD protein networkhttps://string-db.org/network/1415657.FNIIJ_147Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
lysS protein networkhttps://string-db.org/network/1415657.FNIIJ_148lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
argH protein networkhttps://string-db.org/network/1415657.FNIIJ_149Argininosuccinate lyase.
FNIIJ_150 protein networkhttps://string-db.org/network/1415657.FNIIJ_1504Fe-4S ferredoxin.
rpsU protein networkhttps://string-db.org/network/1415657.FNIIJ_151Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
FNIIJ_152 protein networkhttps://string-db.org/network/1415657.FNIIJ_152Putative CAAX amino terminal protease family protein.
truA protein networkhttps://string-db.org/network/1415657.FNIIJ_153tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
rpoC protein networkhttps://string-db.org/network/1415657.FNIIJ_154DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/1415657.FNIIJ_155DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/1415657.FNIIJ_156Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacter [...]
rplJ protein networkhttps://string-db.org/network/1415657.FNIIJ_157Ribosomal protein L10.
rplA protein networkhttps://string-db.org/network/1415657.FNIIJ_158Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/1415657.FNIIJ_159Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/1415657.FNIIJ_160Transcription termination/antitermination factor; Participates in transcription elongation, termination and antitermination.
secE protein networkhttps://string-db.org/network/1415657.FNIIJ_161Putative preprotein translocase subunit SecE; Belongs to the SecE/SEC61-gamma family.
tufA protein networkhttps://string-db.org/network/1415657.FNIIJ_163Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
prfA protein networkhttps://string-db.org/network/1415657.FNIIJ_168Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
rho protein networkhttps://string-db.org/network/1415657.FNIIJ_169Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
trpE protein networkhttps://string-db.org/network/1415657.FNIIJ_170Anthranilate synthase component I.
trpG protein networkhttps://string-db.org/network/1415657.FNIIJ_171Anthranilate synthase component II.
trpD protein networkhttps://string-db.org/network/1415657.FNIIJ_172Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranila [...]
trpF protein networkhttps://string-db.org/network/1415657.FNIIJ_174Phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
trpB protein networkhttps://string-db.org/network/1415657.FNIIJ_175Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpA protein networkhttps://string-db.org/network/1415657.FNIIJ_176Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
menA protein networkhttps://string-db.org/network/1415657.FNIIJ_1771,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
menB protein networkhttps://string-db.org/network/1415657.FNIIJ_178Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
rpsR protein networkhttps://string-db.org/network/1415657.FNIIJ_181Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal p [...]
rpsF protein networkhttps://string-db.org/network/1415657.FNIIJ_182Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
iscS protein networkhttps://string-db.org/network/1415657.FNIIJ_183Cysteine desulfurase.
pheS protein networkhttps://string-db.org/network/1415657.FNIIJ_184phenylalanyl-tRNA synthetase subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
FNIIJ_185 protein networkhttps://string-db.org/network/1415657.FNIIJ_185TrmH family RNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
rpmF protein networkhttps://string-db.org/network/1415657.FNIIJ_187Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
nusB protein networkhttps://string-db.org/network/1415657.FNIIJ_188Transcription antitermination factor NusB.
rpoD protein networkhttps://string-db.org/network/1415657.FNIIJ_189RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
pnp protein networkhttps://string-db.org/network/1415657.FNIIJ_190Polyribonucleotide nucleotidyltransferase (pnpASE); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
rpsO protein networkhttps://string-db.org/network/1415657.FNIIJ_191Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
rpmE2 protein networkhttps://string-db.org/network/1415657.FNIIJ_192Ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family.
gcp protein networkhttps://string-db.org/network/1415657.FNIIJ_193Glycoprotease family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the tr [...]
dapB protein networkhttps://string-db.org/network/1415657.FNIIJ_198Dihydrodipicolinate reductase; Belongs to the DapB family.
lepB protein networkhttps://string-db.org/network/1415657.FNIIJ_199Signal peptidase I; Belongs to the peptidase S26 family.
rbfA protein networkhttps://string-db.org/network/1415657.FNIIJ_200Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
mraW protein networkhttps://string-db.org/network/1415657.FNIIJ_202S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
gidB protein networkhttps://string-db.org/network/1415657.FNIIJ_20416S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
gyrB protein networkhttps://string-db.org/network/1415657.FNIIJ_205DNA gyrase subunit B.
rpsP protein networkhttps://string-db.org/network/1415657.FNIIJ_207Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
FNIIJ_209 protein networkhttps://string-db.org/network/1415657.FNIIJ_209Hypothetical protein.
FNIIJ_210 protein networkhttps://string-db.org/network/1415657.FNIIJ_210FeS assembly SUF system protein.
FNIIJ_211 protein networkhttps://string-db.org/network/1415657.FNIIJ_211Cytochrome c.
nrfC protein networkhttps://string-db.org/network/1415657.FNIIJ_212Molybdopterin oxidoreductase iron-sulfur binding subunit.
nrfD protein networkhttps://string-db.org/network/1415657.FNIIJ_213Molybdopterin oxidoreductase membrane subunit.
FNIIJ_214 protein networkhttps://string-db.org/network/1415657.FNIIJ_214Hypothetical protein.
FNIIJ_215 protein networkhttps://string-db.org/network/1415657.FNIIJ_215Cytochrome c family protein.
FNIIJ_216 protein networkhttps://string-db.org/network/1415657.FNIIJ_216Hypothetical protein.
sufE protein networkhttps://string-db.org/network/1415657.FNIIJ_217SufE Fe/S-cluster-related protein.
groEL protein networkhttps://string-db.org/network/1415657.FNIIJ_21960 kDa chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
groES protein networkhttps://string-db.org/network/1415657.FNIIJ_22010 kDa chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
FNIIJ_221 protein networkhttps://string-db.org/network/1415657.FNIIJ_221Sigma-54-dependent transcriptional regulator.
miaB protein networkhttps://string-db.org/network/1415657.FNIIJ_222(dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine ( [...]
sucB protein networkhttps://string-db.org/network/1415657.FNIIJ_2232-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion o [...]
sucA protein networkhttps://string-db.org/network/1415657.FNIIJ_2242-oxoglutarate dehydrogenase, E1 component.
alaS protein networkhttps://string-db.org/network/1415657.FNIIJ_225alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
trpS protein networkhttps://string-db.org/network/1415657.FNIIJ_227tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
atpF protein networkhttps://string-db.org/network/1415657.FNIIJ_230F0F1 ATP synthase subunit B; Belongs to the ATPase B chain family.
cysS protein networkhttps://string-db.org/network/1415657.FNIIJ_232cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
proS protein networkhttps://string-db.org/network/1415657.FNIIJ_233prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
greA protein networkhttps://string-db.org/network/1415657.FNIIJ_234Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a [...]
rpsT protein networkhttps://string-db.org/network/1415657.FNIIJ_236Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
aroA protein networkhttps://string-db.org/network/1415657.FNIIJ_2375-enolpyruvyl shikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
aroG/pheA protein networkhttps://string-db.org/network/1415657.FNIIJ_238Putative phospho-2-dehydro-3-deoxyheptonate aldolase (aroG)/chorismate mutase (pheA).
infB protein networkhttps://string-db.org/network/1415657.FNIIJ_239Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
nusA protein networkhttps://string-db.org/network/1415657.FNIIJ_240Transcription factor NusA, N-terminal domain protein; Participates in both transcription termination and antitermination.
hisG protein networkhttps://string-db.org/network/1415657.FNIIJ_243ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
hisB protein networkhttps://string-db.org/network/1415657.FNIIJ_244Bifunctional imidazole glycerol-phosphate dehydratase, histidinol phosphatase.
hisH protein networkhttps://string-db.org/network/1415657.FNIIJ_245Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glu [...]
hisA protein networkhttps://string-db.org/network/1415657.FNIIJ_2461-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase.
hisF protein networkhttps://string-db.org/network/1415657.FNIIJ_247Imidazole glycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that [...]
hisIE protein networkhttps://string-db.org/network/1415657.FNIIJ_248Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
ksgA protein networkhttps://string-db.org/network/1415657.FNIIJ_249Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
lgt protein networkhttps://string-db.org/network/1415657.FNIIJ_250Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
nrdB protein networkhttps://string-db.org/network/1415657.FNIIJ_251Ribonucleoside-diphosphate reductase subunit beta.
nrdE protein networkhttps://string-db.org/network/1415657.FNIIJ_252Ribonucleotide-diphosphate reductase subunit alpha.
ispB protein networkhttps://string-db.org/network/1415657.FNIIJ_260Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
ccmC protein networkhttps://string-db.org/network/1415657.FNIIJ_261Cytochrome c assembly protein.
mutS protein networkhttps://string-db.org/network/1415657.FNIIJ_264DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase act [...]
clpX protein networkhttps://string-db.org/network/1415657.FNIIJ_265ATP-dependent protease ATP-binding subunit.
clpP protein networkhttps://string-db.org/network/1415657.FNIIJ_266ATP-dependent Clp protease proteolytic subunit 2; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degra [...]
FNIIJ_267 protein networkhttps://string-db.org/network/1415657.FNIIJ_267Putative cell division trigger factor.
tatB protein networkhttps://string-db.org/network/1415657.FNIIJ_268Sec-independent protein translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal pe [...]
dnaX protein networkhttps://string-db.org/network/1415657.FNIIJ_269DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' [...]
sucC protein networkhttps://string-db.org/network/1415657.FNIIJ_270succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus repr [...]
asd protein networkhttps://string-db.org/network/1415657.FNIIJ_271Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the as [...]
FNIIJ_272 protein networkhttps://string-db.org/network/1415657.FNIIJ_272tRNA/rRNA methyltransferase family protein.
FNIIJ_273 protein networkhttps://string-db.org/network/1415657.FNIIJ_273Putative ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as [...]
sufS protein networkhttps://string-db.org/network/1415657.FNIIJ_274Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
sufD protein networkhttps://string-db.org/network/1415657.FNIIJ_275FeS assembly protein SufD.
sufC protein networkhttps://string-db.org/network/1415657.FNIIJ_276FeS assembly ATPase SufC.
sufB protein networkhttps://string-db.org/network/1415657.FNIIJ_277Cysteine desulfurase activator complex subunit SufB.
lepA protein networkhttps://string-db.org/network/1415657.FNIIJ_278GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
rplU protein networkhttps://string-db.org/network/1415657.FNIIJ_279Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
rpmA protein networkhttps://string-db.org/network/1415657.FNIIJ_280Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
serS protein networkhttps://string-db.org/network/1415657.FNIIJ_281serine-tRNA synthetase.
metF protein networkhttps://string-db.org/network/1415657.FNIIJ_2825,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
frr protein networkhttps://string-db.org/network/1415657.FNIIJ_283Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
asnS protein networkhttps://string-db.org/network/1415657.FNIIJ_284asparaginyl-tRNA synthetase.
rpoN protein networkhttps://string-db.org/network/1415657.FNIIJ_285RNA polymerase sigma 54 subunit.
gltX protein networkhttps://string-db.org/network/1415657.FNIIJ_288glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
acp protein networkhttps://string-db.org/network/1415657.FNIIJ_289Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
leuB protein networkhttps://string-db.org/network/1415657.FNIIJ_2903-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
leuD protein networkhttps://string-db.org/network/1415657.FNIIJ_2913-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. Leu [...]
leuC protein networkhttps://string-db.org/network/1415657.FNIIJ_2923-isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
leuA protein networkhttps://string-db.org/network/1415657.FNIIJ_2932-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
tyrS protein networkhttps://string-db.org/network/1415657.FNIIJ_294tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
era protein networkhttps://string-db.org/network/1415657.FNIIJ_295Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possi [...]
ysxC protein networkhttps://string-db.org/network/1415657.FNIIJ_296Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase sup [...]
aroD protein networkhttps://string-db.org/network/1415657.FNIIJ_2973-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
rluB protein networkhttps://string-db.org/network/1415657.FNIIJ_298Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family.
pth protein networkhttps://string-db.org/network/1415657.FNIIJ_300peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
rluD protein networkhttps://string-db.org/network/1415657.FNIIJ_301Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
rseP protein networkhttps://string-db.org/network/1415657.FNIIJ_302M50 family membrane-associated zinc metalloprotease.
FNIIJ_303 protein networkhttps://string-db.org/network/1415657.FNIIJ_3034Fe-4S ferredoxin.
FNIIJ_304 protein networkhttps://string-db.org/network/1415657.FNIIJ_304Peptidase U32.
holB protein networkhttps://string-db.org/network/1415657.FNIIJ_305DNA polymerase III subunit delta'.
leuS protein networkhttps://string-db.org/network/1415657.FNIIJ_306leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.