Organism Overview: secondary endosymbiont of Heteropsylla


 
dnaA protein networkhttps://string-db.org/network/134287.A35E_00001Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically doub [...]
A35E_00002 protein networkhttps://string-db.org/network/134287.A35E_00002DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadi [...]
A35E_00003 protein networkhttps://string-db.org/network/134287.A35E_00003Transcriptional regulator; PFAM: MarR family.
A35E_00004 protein networkhttps://string-db.org/network/134287.A35E_00004Cysteine export CydDC family ABC transporter permease subunit/ATP-binding protein CydC; PFAM: ABC transporter; TIGRFAM: thiol reductant ABC exporter, CydC subunit.
A35E_00005 protein networkhttps://string-db.org/network/134287.A35E_00005Cysteine export CydDC family ABC transporter permease subunit/ATP-binding protein CydD; PFAM: ABC transporter transmembrane region; ABC transporter; TIGRFAM: thiol reductant ABC exporter, CydD su [...]
A35E_00006 protein networkhttps://string-db.org/network/134287.A35E_00006PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.
pcnB protein networkhttps://string-db.org/network/134287.A35E_00007poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencin [...]
A35E_00008 protein networkhttps://string-db.org/network/134287.A35E_00008Putative permease; PFAM: Domain of unknown function DUF20.
aspS protein networkhttps://string-db.org/network/134287.A35E_00009aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
A35E_00011 protein networkhttps://string-db.org/network/134287.A35E_00011Hypothetical protein.
A35E_00012 protein networkhttps://string-db.org/network/134287.A35E_00012Hypothetical protein.
glmU protein networkhttps://string-db.org/network/134287.A35E_00013UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (U [...]
glmS protein networkhttps://string-db.org/network/134287.A35E_00014Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [...]
A35E_00015 protein networkhttps://string-db.org/network/134287.A35E_00015Membrane-bound metallopeptidase; PFAM: Peptidase family M23.
rpmA protein networkhttps://string-db.org/network/134287.A35E_00016PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
rplU protein networkhttps://string-db.org/network/134287.A35E_00017Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
hslU protein networkhttps://string-db.org/network/134287.A35E_00018ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by Hsl [...]
hslV protein networkhttps://string-db.org/network/134287.A35E_00019ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
rpoH protein networkhttps://string-db.org/network/134287.A35E_00020Alternative sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved [...]
bamD protein networkhttps://string-db.org/network/134287.A35E_00021Outer membrane assembly lipoprotein YfiO; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constit [...]
A35E_00022 protein networkhttps://string-db.org/network/134287.A35E_00022Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
ligA protein networkhttps://string-db.org/network/134287.A35E_00023DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as t [...]
A35E_00024 protein networkhttps://string-db.org/network/134287.A35E_00024PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase).
cmk protein networkhttps://string-db.org/network/134287.A35E_00025PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
A35E_00026 protein networkhttps://string-db.org/network/134287.A35E_00026Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
A35E_00027 protein networkhttps://string-db.org/network/134287.A35E_00027Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tra [...]
A35E_00028 protein networkhttps://string-db.org/network/134287.A35E_00028PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family.
A35E_00029 protein networkhttps://string-db.org/network/134287.A35E_000293-carboxymuconate cyclase; PFAM: 3-carboxy-cis,cis-muconate lactonizing enzyme.
A35E_00030 protein networkhttps://string-db.org/network/134287.A35E_00030Putative periplasmic or secreted lipoprotein; PFAM: Putative phospholipid-binding domain.
guaC protein networkhttps://string-db.org/network/134287.A35E_00031Guanosine monophosphate reductase, eukaryotic; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide deriva [...]
engB protein networkhttps://string-db.org/network/134287.A35E_00032Ribosome biogenesis GTP-binding protein YsxC/EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPas [...]
obg protein networkhttps://string-db.org/network/134287.A35E_00035Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a ro [...]
A35E_00036 protein networkhttps://string-db.org/network/134287.A35E_00036Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
A35E_00037 protein networkhttps://string-db.org/network/134287.A35E_00037TIGR00255 family protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein.
A35E_00039 protein networkhttps://string-db.org/network/134287.A35E_00039acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier [...]
A35E_00040 protein networkhttps://string-db.org/network/134287.A35E_00040acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the car [...]
A35E_00041 protein networkhttps://string-db.org/network/134287.A35E_00041Cytochrome bd-type quinol oxidase, subunit 1; PFAM: Bacterial Cytochrome Ubiquinol Oxidase.
A35E_00042 protein networkhttps://string-db.org/network/134287.A35E_00042PFAM: Cytochrome oxidase subunit II; TIGRFAM: cytochrome d oxidase, subunit II (cydB).
nadK protein networkhttps://string-db.org/network/134287.A35E_00043Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-h [...]
A35E_00044 protein networkhttps://string-db.org/network/134287.A35E_00044PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ.
dxs protein networkhttps://string-db.org/network/134287.A35E_000451-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (D [...]
A35E_00046 protein networkhttps://string-db.org/network/134287.A35E_00046Hypothetical protein.
trpA protein networkhttps://string-db.org/network/134287.A35E_00048Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
trpB protein networkhttps://string-db.org/network/134287.A35E_00049Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpF protein networkhttps://string-db.org/network/134287.A35E_00050PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpC family.
trpD protein networkhttps://string-db.org/network/134287.A35E_00051Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranila [...]
A35E_00054 protein networkhttps://string-db.org/network/134287.A35E_00054ABC-type Mn2+/Zn2+ transport system, permease component; PFAM: ABC 3 transport family.
znuC protein networkhttps://string-db.org/network/134287.A35E_00055ATPase component of Mn/Zn ABC-type transporter; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC tra [...]
A35E_00056 protein networkhttps://string-db.org/network/134287.A35E_00056ABC-type Zn2+ transport system, periplasmic component/surface adhesin; PFAM: Periplasmic solute binding protein family.
A35E_00057 protein networkhttps://string-db.org/network/134287.A35E_00057Metalloendopeptidase-like membrane protein; PFAM: Opacity-associated protein A LysM-like domain; Peptidase family M23.
recD protein networkhttps://string-db.org/network/134287.A35E_00058DNA helicase/exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and proce [...]
recB protein networkhttps://string-db.org/network/134287.A35E_00059DNA helicase/exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and proces [...]
A35E_00060 protein networkhttps://string-db.org/network/134287.A35E_00060RNA methyltransferase, RsmD family; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
nth protein networkhttps://string-db.org/network/134287.A35E_00061Endonuclease III, DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various dama [...]
tdk protein networkhttps://string-db.org/network/134287.A35E_00062PFAM: Thymidine kinase.
A35E_00063 protein networkhttps://string-db.org/network/134287.A35E_00063PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
ftsY protein networkhttps://string-db.org/network/134287.A35E_00065Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the [...]
A35E_00066 protein networkhttps://string-db.org/network/134287.A35E_00066PFAM: ABC transporter; TIGRFAM: cell division ATP-binding protein FtsE.
A35E_00067 protein networkhttps://string-db.org/network/134287.A35E_00067Cell division protein; PFAM: Predicted permease.
rpmG protein networkhttps://string-db.org/network/134287.A35E_00068PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/134287.A35E_00069PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
A35E_00070 protein networkhttps://string-db.org/network/134287.A35E_00070Putative HD superfamily hydrolase; PFAM: HD domain.
prs protein networkhttps://string-db.org/network/134287.A35E_00071Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
A35E_00072 protein networkhttps://string-db.org/network/134287.A35E_00072Hypothetical protein; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase.
A35E_00073 protein networkhttps://string-db.org/network/134287.A35E_00073Hypothetical protein.
lolB protein networkhttps://string-db.org/network/134287.A35E_00074Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
kdsA protein networkhttps://string-db.org/network/134287.A35E_00075PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family.
A35E_00077 protein networkhttps://string-db.org/network/134287.A35E_00077Hypothetical protein.
A35E_00078 protein networkhttps://string-db.org/network/134287.A35E_00078Helicase subunit of the DNA excision repair complex; PFAM: Helicase conserved C-terminal domain.
mntH protein networkhttps://string-db.org/network/134287.A35E_00080Natural resistance-associated macrophage protein metal ion transporter NRAMP; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
A35E_00081 protein networkhttps://string-db.org/network/134287.A35E_00081Rhodanese-related sulfurtransferase; PFAM: Rhodanese-like domain.
A35E_00082 protein networkhttps://string-db.org/network/134287.A35E_00082Glutaredoxin, GrxC family; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
secB protein networkhttps://string-db.org/network/134287.A35E_00083Protein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor protein [...]
gpsA protein networkhttps://string-db.org/network/134287.A35E_00084PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase fam [...]
A35E_00085 protein networkhttps://string-db.org/network/134287.A35E_00085Enoyl-(acyl-carrier-protein) reductase (NADH); PFAM: short chain dehydrogenase.
coaD protein networkhttps://string-db.org/network/134287.A35E_00086Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial Co [...]
argS protein networkhttps://string-db.org/network/134287.A35E_00087arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase.
coaE protein networkhttps://string-db.org/network/134287.A35E_00088dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
A35E_00094 protein networkhttps://string-db.org/network/134287.A35E_00094PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB.
A35E_00095 protein networkhttps://string-db.org/network/134287.A35E_00095Phosphate/sulfate permease; PFAM: Phosphate transporter family.
murJ protein networkhttps://string-db.org/network/134287.A35E_00096Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
tpiA protein networkhttps://string-db.org/network/134287.A35E_00097Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
infA protein networkhttps://string-db.org/network/134287.A35E_00098Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
asnS protein networkhttps://string-db.org/network/134287.A35E_00099PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase.
A35E_00101 protein networkhttps://string-db.org/network/134287.A35E_00101Outer membrane protein; PFAM: Surface antigen.
A35E_00102 protein networkhttps://string-db.org/network/134287.A35E_00102Hypothetical protein; PFAM: Family of unknown function (DUF490).
A35E_00103 protein networkhttps://string-db.org/network/134287.A35E_001032-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
hldD protein networkhttps://string-db.org/network/134287.A35E_00104ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the [...]
A35E_00105 protein networkhttps://string-db.org/network/134287.A35E_00105Lipopolysaccharide heptosyltransferase II; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase II.
A35E_00106 protein networkhttps://string-db.org/network/134287.A35E_00106PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase I.
A35E_00107 protein networkhttps://string-db.org/network/134287.A35E_00107Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
A35E_00108 protein networkhttps://string-db.org/network/134287.A35E_00108Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
A35E_00109 protein networkhttps://string-db.org/network/134287.A35E_00109PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family.
hda protein networkhttps://string-db.org/network/134287.A35E_00110Regulatory inactivation of DnaA Hda protein; Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of AT [...]
hspQ protein networkhttps://string-db.org/network/134287.A35E_00111Hemimethylated DNA binding domain protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.
tal protein networkhttps://string-db.org/network/134287.A35E_00112Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
A35E_00113 protein networkhttps://string-db.org/network/134287.A35E_00113Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
trpS protein networkhttps://string-db.org/network/134287.A35E_00114tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
pth protein networkhttps://string-db.org/network/134287.A35E_00115peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
ychF protein networkhttps://string-db.org/network/134287.A35E_00116GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
kdsB protein networkhttps://string-db.org/network/134287.A35E_001173-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
apaH protein networkhttps://string-db.org/network/134287.A35E_00118Symmetrical bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
A35E_00119 protein networkhttps://string-db.org/network/134287.A35E_00119PFAM: Glutaredoxin; TIGRFAM: monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily.
rnt protein networkhttps://string-db.org/network/134287.A35E_00120Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP [...]
tilS protein networkhttps://string-db.org/network/134287.A35E_00121tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is [...]
murB protein networkhttps://string-db.org/network/134287.A35E_00122UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
birA protein networkhttps://string-db.org/network/134287.A35E_00123birA, biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA- [...]
dnaJ protein networkhttps://string-db.org/network/134287.A35E_00124Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an [...]
dnaK protein networkhttps://string-db.org/network/134287.A35E_00125Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
rplI protein networkhttps://string-db.org/network/134287.A35E_00126Ribosomal protein L9; Binds to the 23S rRNA.
rpsR protein networkhttps://string-db.org/network/134287.A35E_00127Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal p [...]
A35E_00128 protein networkhttps://string-db.org/network/134287.A35E_00128Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS).
rpsF protein networkhttps://string-db.org/network/134287.A35E_00129Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
djlA protein networkhttps://string-db.org/network/134287.A35E_00131Protein with DnaJ-like domain; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic ac [...]
lptD protein networkhttps://string-db.org/network/134287.A35E_00132Organic solvent tolerance protein OstA; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
surA protein networkhttps://string-db.org/network/134287.A35E_00133Parvulin-like peptidyl-prolyl isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation o [...]
pdxA protein networkhttps://string-db.org/network/134287.A35E_001344-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decar [...]
rsmA protein networkhttps://string-db.org/network/134287.A35E_00135Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
A35E_00136 protein networkhttps://string-db.org/network/134287.A35E_00136Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
dusA protein networkhttps://string-db.org/network/134287.A35E_00137tRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines [...]
A35E_00140 protein networkhttps://string-db.org/network/134287.A35E_00140EF-P lysine aminoacylase GenX; PFAM: tRNA synthetases class II (D, K and N); TIGRFAM: EF-P lysine aminoacylase GenX.
murI protein networkhttps://string-db.org/network/134287.A35E_00141Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
A35E_00142 protein networkhttps://string-db.org/network/134287.A35E_00142PFAM: Mechanosensitive ion channel.
psd protein networkhttps://string-db.org/network/134287.A35E_00143Phosphatidylserine decarboxylase precursor; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
deoB protein networkhttps://string-db.org/network/134287.A35E_00144Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
deoD protein networkhttps://string-db.org/network/134287.A35E_00145PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD).
pal protein networkhttps://string-db.org/network/134287.A35E_00146Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
era protein networkhttps://string-db.org/network/134287.A35E_00147GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly als [...]
rnc protein networkhttps://string-db.org/network/134287.A35E_00148Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
A35E_00149 protein networkhttps://string-db.org/network/134287.A35E_00149PFAM: Peptidase S26; Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
lepA protein networkhttps://string-db.org/network/134287.A35E_00150GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
gltX protein networkhttps://string-db.org/network/134287.A35E_00151glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
bioD protein networkhttps://string-db.org/network/134287.A35E_00152Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an urei [...]
bioB protein networkhttps://string-db.org/network/134287.A35E_00153Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily [...]
A35E_00155 protein networkhttps://string-db.org/network/134287.A35E_00155PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase family M24; Belongs to the peptidase M24B family.
A35E_00156 protein networkhttps://string-db.org/network/134287.A35E_00156Zn-dependent hydrolase, glyoxylase; PFAM: Metallo-beta-lactamase superfamily.
glyQ protein networkhttps://string-db.org/network/134287.A35E_00157PFAM: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, alpha subunit.
glyS protein networkhttps://string-db.org/network/134287.A35E_00158PFAM: Glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, beta subunit.
A35E_00159 protein networkhttps://string-db.org/network/134287.A35E_00159PFAM: Na+ dependent nucleoside transporter C-terminus; Na+ dependent nucleoside transporter N-terminus; TIGRFAM: nucleoside transporter.
metK protein networkhttps://string-db.org/network/134287.A35E_00160Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet format [...]
polA protein networkhttps://string-db.org/network/134287.A35E_00162DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
mnmG protein networkhttps://string-db.org/network/134287.A35E_00163Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s( [...]
A35E_00164 protein networkhttps://string-db.org/network/134287.A35E_00164Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
A35E_00165 protein networkhttps://string-db.org/network/134287.A35E_00165Putative integral membrane protein; PFAM: YGGT family.
A35E_00166 protein networkhttps://string-db.org/network/134287.A35E_00166Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalentl [...]
A35E_00167 protein networkhttps://string-db.org/network/134287.A35E_00167Sulfur relay protein, TusE/DsrC/DsvC family; Part of a sulfur-relay system.
orn protein networkhttps://string-db.org/network/134287.A35E_00168Oligoribonuclease (3'->5' exoribonuclease); 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
accD protein networkhttps://string-db.org/network/134287.A35E_00169acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carr [...]
A35E_00170 protein networkhttps://string-db.org/network/134287.A35E_00170Folylpolyglutamate synthase/dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroat [...]
A35E_00171 protein networkhttps://string-db.org/network/134287.A35E_00171Peroxiredoxin; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family.
groL protein networkhttps://string-db.org/network/134287.A35E_00172Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
groS protein networkhttps://string-db.org/network/134287.A35E_00173Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
lpxL protein networkhttps://string-db.org/network/134287.A35E_00174Lipid A biosynthesis lauroyl/palmitoleoyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
A35E_00175 protein networkhttps://string-db.org/network/134287.A35E_00175Putative membrane protein, required for colicin V production; PFAM: Colicin V production protein.
hldE protein networkhttps://string-db.org/network/134287.A35E_00176D-heptose-7- phosphate 1-kinase,D-heptose-1-phosphate adenylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- [...]
ribB protein networkhttps://string-db.org/network/134287.A35E_001773,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
pgi protein networkhttps://string-db.org/network/134287.A35E_00178PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
htpG protein networkhttps://string-db.org/network/134287.A35E_00179Molecular chaperone of HSP90 family; Molecular chaperone. Has ATPase activity.
adk protein networkhttps://string-db.org/network/134287.A35E_00180Adenylate kinase family protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucle [...]
guaA protein networkhttps://string-db.org/network/134287.A35E_00181GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
A35E_00182 protein networkhttps://string-db.org/network/134287.A35E_00182Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
proS protein networkhttps://string-db.org/network/134287.A35E_00183prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
prfC protein networkhttps://string-db.org/network/134287.A35E_00184Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for U [...]
A35E_00185 protein networkhttps://string-db.org/network/134287.A35E_00185PFAM: Radical SAM superfamily; TIGRFAM: KamA family protein; lysine-2,3-aminomutase-related protein.
bioA protein networkhttps://string-db.org/network/134287.A35E_00186Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-dia [...]
tyrS protein networkhttps://string-db.org/network/134287.A35E_00187tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
pdxH protein networkhttps://string-db.org/network/134287.A35E_00188Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
arnT protein networkhttps://string-db.org/network/134287.A35E_00189PMT family glycosyltransferase, 4-amino-4-deoxy-L-arabinose transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modifi [...]
arnD protein networkhttps://string-db.org/network/134287.A35E_00190Putative xylanase/chitin deacetylase; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabino [...]
arnA protein networkhttps://string-db.org/network/134287.A35E_00191methionyl-tRNA formyltransferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a fo [...]
arnC protein networkhttps://string-db.org/network/134287.A35E_00192Glycosyl transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to [...]
A35E_00193 protein networkhttps://string-db.org/network/134287.A35E_00193Hypothetical protein.
A35E_00194 protein networkhttps://string-db.org/network/134287.A35E_00194PFAM: Glycosyl transferase family 2.
A35E_00195 protein networkhttps://string-db.org/network/134287.A35E_001953-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV( [...]
A35E_00196 protein networkhttps://string-db.org/network/134287.A35E_00196Glycosyltransferase; PFAM: Glycosyl transferases group 1.
A35E_00197 protein networkhttps://string-db.org/network/134287.A35E_00197DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonu [...]
A35E_00198 protein networkhttps://string-db.org/network/134287.A35E_001983-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorga [...]
lptC protein networkhttps://string-db.org/network/134287.A35E_00199Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS fr [...]
lptA protein networkhttps://string-db.org/network/134287.A35E_00200Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. M [...]
A35E_00201 protein networkhttps://string-db.org/network/134287.A35E_00201ABC-type (unclassified) transport system, ATPase component; PFAM: ABC transporter.
acpS protein networkhttps://string-db.org/network/134287.A35E_00202Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
pdxJ protein networkhttps://string-db.org/network/134287.A35E_00203Pyridoxine 5''-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-ami [...]
A35E_00204 protein networkhttps://string-db.org/network/134287.A35E_00204L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
A35E_00205 protein networkhttps://string-db.org/network/134287.A35E_00205DNA recombination-dependent growth factor C; May be involved in recombination. Belongs to the RdgC family.
A35E_00207 protein networkhttps://string-db.org/network/134287.A35E_00207PFAM: Protein of unknown function (DUF496); Belongs to the UPF0265 family.
A35E_00208 protein networkhttps://string-db.org/network/134287.A35E_00208SufE protein probably involved in Fe-S center assembly; PFAM: Fe-S metabolism associated domain.
A35E_00209 protein networkhttps://string-db.org/network/134287.A35E_00209Cysteine desulfurase-like protein, SufS subfamily; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a varie [...]
A35E_00210 protein networkhttps://string-db.org/network/134287.A35E_00210FeS assembly protein SufD; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD.
A35E_00211 protein networkhttps://string-db.org/network/134287.A35E_00211PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC.
A35E_00212 protein networkhttps://string-db.org/network/134287.A35E_00212FeS assembly protein SufB; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB.
A35E_00213 protein networkhttps://string-db.org/network/134287.A35E_00213PFAM: Iron-sulphur cluster biosynthesis; TIGRFAM: FeS assembly scaffold SufA; Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
A35E_00214 protein networkhttps://string-db.org/network/134287.A35E_00214PFAM: Predicted permease YjgP/YjgQ family.
A35E_00215 protein networkhttps://string-db.org/network/134287.A35E_00215PFAM: Predicted permease YjgP/YjgQ family.
A35E_00217 protein networkhttps://string-db.org/network/134287.A35E_00217PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
A35E_00218 protein networkhttps://string-db.org/network/134287.A35E_00218Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate ac [...]
A35E_00219 protein networkhttps://string-db.org/network/134287.A35E_00219TIGR00255 family protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein.
clsA protein networkhttps://string-db.org/network/134287.A35E_00220Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin ( [...]
nadE protein networkhttps://string-db.org/network/134287.A35E_00221NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
rlmB protein networkhttps://string-db.org/network/134287.A35E_00222rRNA methylase, putative, group 3; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase [...]
rnr protein networkhttps://string-db.org/network/134287.A35E_00223Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily.
purA protein networkhttps://string-db.org/network/134287.A35E_00224Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
A35E_00225 protein networkhttps://string-db.org/network/134287.A35E_00225HflC protein; HflC and HflK could regulate a protease.
A35E_00226 protein networkhttps://string-db.org/network/134287.A35E_00226HflK protein; HflC and HflK could encode or regulate a protease.
hfq protein networkhttps://string-db.org/network/134287.A35E_00227RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in [...]
miaA protein networkhttps://string-db.org/network/134287.A35E_00228tRNA isopentenyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6- [...]
A35E_00229 protein networkhttps://string-db.org/network/134287.A35E_00229DNA mismatch repair enzyme (predicted ATPase); PFAM: MutL C terminal dimerisation domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA mismatch repair protein, C-terminal domain; [...]
A35E_00230 protein networkhttps://string-db.org/network/134287.A35E_00230PFAM: N-acetylmuramoyl-L-alanine amidase; LysM domain.
A35E_00231 protein networkhttps://string-db.org/network/134287.A35E_00231ATPase, YjeE family; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family.
A35E_00233 protein networkhttps://string-db.org/network/134287.A35E_00233Hypothetical protein.
A35E_00234 protein networkhttps://string-db.org/network/134287.A35E_00234Hypothetical protein.
A35E_00235 protein networkhttps://string-db.org/network/134287.A35E_00235Hypothetical protein.
A35E_00237 protein networkhttps://string-db.org/network/134287.A35E_002372-polyprenylphenol hydroxylase-like oxidoreductase; PFAM: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain.
ffh protein networkhttps://string-db.org/network/134287.A35E_00238Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of [...]
rpsP protein networkhttps://string-db.org/network/134287.A35E_00239PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
rimM protein networkhttps://string-db.org/network/134287.A35E_0024016S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19 [...]
trmD protein networkhttps://string-db.org/network/134287.A35E_00241tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rplS protein networkhttps://string-db.org/network/134287.A35E_00242Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
A35E_00243 protein networkhttps://string-db.org/network/134287.A35E_00243Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
A35E_00245 protein networkhttps://string-db.org/network/134287.A35E_00245Putative membrane protein; PFAM: YhhN-like protein.
A35E_00246 protein networkhttps://string-db.org/network/134287.A35E_00246Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
A35E_00247 protein networkhttps://string-db.org/network/134287.A35E_00247PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long for [...]
A35E_00248 protein networkhttps://string-db.org/network/134287.A35E_00248Pyruvate dehydrogenase E1 component, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
ribA protein networkhttps://string-db.org/network/134287.A35E_00249GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
A35E_00250 protein networkhttps://string-db.org/network/134287.A35E_00250Membrane-associated phospholipid phosphatase; PFAM: PAP2 superfamily.
A35E_00251 protein networkhttps://string-db.org/network/134287.A35E_00251Hypothetical protein.
A35E_00252 protein networkhttps://string-db.org/network/134287.A35E_00252Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of th [...]
A35E_00253 protein networkhttps://string-db.org/network/134287.A35E_00253Flavodoxin reductase family protein; PFAM: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain.
tusA protein networkhttps://string-db.org/network/134287.A35E_00254Putative redox protein, regulator of disulfide bond formation; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during sy [...]
rplY protein networkhttps://string-db.org/network/134287.A35E_00255Ribosomal protein L25 (general stress protein Ctc); This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial [...]
A35E_00257 protein networkhttps://string-db.org/network/134287.A35E_00257PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
A35E_00258 protein networkhttps://string-db.org/network/134287.A35E_00258ATPase component of ABC transporters with duplicated ATPase domain; PFAM: ABC transporter.
A35E_00259 protein networkhttps://string-db.org/network/134287.A35E_00259PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
A35E_00260 protein networkhttps://string-db.org/network/134287.A35E_00260Leucyl aminopeptidase; Probably plays an important role in intracellular peptide degradation.
A35E_00263 protein networkhttps://string-db.org/network/134287.A35E_00263NADH dehydrogenase, FAD-containing subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
A35E_00264 protein networkhttps://string-db.org/network/134287.A35E_00264Ferredoxin; PFAM: 2Fe-2S iron-sulfur cluster binding domain.
pgk protein networkhttps://string-db.org/network/134287.A35E_00266PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
A35E_00267 protein networkhttps://string-db.org/network/134287.A35E_00267Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-b [...]
A35E_00268 protein networkhttps://string-db.org/network/134287.A35E_00268Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase.
leuS protein networkhttps://string-db.org/network/134287.A35E_00269PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; Belongs to the class-I aminoacyl-tRNA synthetase f [...]
lptE protein networkhttps://string-db.org/network/134287.A35E_00270Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may s [...]
A35E_00271 protein networkhttps://string-db.org/network/134287.A35E_00271PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
nadD protein networkhttps://string-db.org/network/134287.A35E_00272Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
mrdA protein networkhttps://string-db.org/network/134287.A35E_00273Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
mrdB protein networkhttps://string-db.org/network/134287.A35E_00274Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
gyrA protein networkhttps://string-db.org/network/134287.A35E_00275DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
rplQ protein networkhttps://string-db.org/network/134287.A35E_00276PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17.
rpoA protein networkhttps://string-db.org/network/134287.A35E_00277DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpsD protein networkhttps://string-db.org/network/134287.A35E_00278Ribosomal protein S4, bacterial/organelle type; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpsK protein networkhttps://string-db.org/network/134287.A35E_0027930S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
A35E_00280 protein networkhttps://string-db.org/network/134287.A35E_00280PFAM: Ribosomal protein S13/S18; TIGRFAM: 30S ribosomal protein S13.
rpmJ protein networkhttps://string-db.org/network/134287.A35E_00282PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type; Belongs to the bacterial ribosomal protein bL36 family.
secY protein networkhttps://string-db.org/network/134287.A35E_00283Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral [...]
rplO protein networkhttps://string-db.org/network/134287.A35E_00284Ribosomal protein L15, bacterial/organelle; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
rpmD protein networkhttps://string-db.org/network/134287.A35E_00285PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle.
rpsE protein networkhttps://string-db.org/network/134287.A35E_00286Ribosomal protein S5, bacterial/organelle type; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal rib [...]
rplR protein networkhttps://string-db.org/network/134287.A35E_00287Ribosomal protein L18, bacterial type; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the centr [...]
rplF protein networkhttps://string-db.org/network/134287.A35E_00288Ribosomal protein L6, bacterial type; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, an [...]
rpsH protein networkhttps://string-db.org/network/134287.A35E_00289Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the [...]
rpsN protein networkhttps://string-db.org/network/134287.A35E_00290Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the univer [...]
rplE protein networkhttps://string-db.org/network/134287.A35E_00291Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In [...]
rplX protein networkhttps://string-db.org/network/134287.A35E_00292Ribosomal protein L24, bacterial/organelle; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplN protein networkhttps://string-db.org/network/134287.A35E_00293Ribosomal protein L14, bacterial/organelle; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rpsQ protein networkhttps://string-db.org/network/134287.A35E_0029430S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rpmC protein networkhttps://string-db.org/network/134287.A35E_00295PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
rplP protein networkhttps://string-db.org/network/134287.A35E_00296Ribosomal protein L16, bacterial/organelle; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsC protein networkhttps://string-db.org/network/134287.A35E_00297Ribosomal protein S3, bacterial type; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 [...]
rplV protein networkhttps://string-db.org/network/134287.A35E_00298Ribosomal protein L22, bacterial type; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that l [...]
rpsS protein networkhttps://string-db.org/network/134287.A35E_00299Ribosomal protein S19, bacterial/organelle; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplB protein networkhttps://string-db.org/network/134287.A35E_00300Ribosomal protein L2, bacterial/organellar; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide b [...]
rplW protein networkhttps://string-db.org/network/134287.A35E_00301Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking [...]
rplD protein networkhttps://string-db.org/network/134287.A35E_0030250S ribosomal protein L4, bacterial/organelle; Forms part of the polypeptide exit tunnel.
rplC protein networkhttps://string-db.org/network/134287.A35E_0030350S ribosomal protein L3, bacterial; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rpsJ protein networkhttps://string-db.org/network/134287.A35E_00304Ribosomal protein S10, bacterial/organelle; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rho protein networkhttps://string-db.org/network/134287.A35E_00305Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
A35E_00306 protein networkhttps://string-db.org/network/134287.A35E_00306TDP-4-keto-6-deoxy-D-glucose transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; TIGRFAM: TDP-4-keto-6-deoxy-D-glucose transaminase; Belongs to the DegT/DnrJ/EryC1 family.
rsmI protein networkhttps://string-db.org/network/134287.A35E_00307Putative S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
rpmH protein networkhttps://string-db.org/network/134287.A35E_00308PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type; Belongs to the bacterial ribosomal protein bL34 family.
rnpA protein networkhttps://string-db.org/network/134287.A35E_00309Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]
A35E_00310 protein networkhttps://string-db.org/network/134287.A35E_00310Conserved hypothetical protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
yidC protein networkhttps://string-db.org/network/134287.A35E_00311Membrane protein insertase, YidC/Oxa1 family, N-terminal domain protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. [...]
mnmE protein networkhttps://string-db.org/network/134287.A35E_00312tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
gloB protein networkhttps://string-db.org/network/134287.A35E_00313Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
A35E_00314 protein networkhttps://string-db.org/network/134287.A35E_00314Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
lysS protein networkhttps://string-db.org/network/134287.A35E_00315lysyl-tRNA synthetase (class II); PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belon [...]
gpmA protein networkhttps://string-db.org/network/134287.A35E_00316Phosphoglycerate mutase, BPG-dependent, family 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM s [...]
panC protein networkhttps://string-db.org/network/134287.A35E_00317Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase f [...]
panB protein networkhttps://string-db.org/network/134287.A35E_003183-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to [...]
tsaD protein networkhttps://string-db.org/network/134287.A35E_00319Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the tran [...]
rpoC protein networkhttps://string-db.org/network/134287.A35E_00320DNA-directed RNA polymerase, beta'' subunit, predominant form; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/134287.A35E_00321DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/134287.A35E_00323Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacter [...]
rplJ protein networkhttps://string-db.org/network/134287.A35E_00324Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein [...]
rplA protein networkhttps://string-db.org/network/134287.A35E_00325Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/134287.A35E_0032650S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/134287.A35E_00327Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the [...]
secE protein networkhttps://string-db.org/network/134287.A35E_00328Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; B [...]
A35E_00330 protein networkhttps://string-db.org/network/134287.A35E_00330Hypothetical protein.
A35E_00332 protein networkhttps://string-db.org/network/134287.A35E_00332Hypothetical protein.
queC protein networkhttps://string-db.org/network/134287.A35E_00334Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
A35E_00335 protein networkhttps://string-db.org/network/134287.A35E_00335PFAM: DNA polymerase III chi subunit, HolC.
valS protein networkhttps://string-db.org/network/134287.A35E_00337valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
smpB protein networkhttps://string-db.org/network/134287.A35E_00338SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
cysS protein networkhttps://string-db.org/network/134287.A35E_00343PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
folD protein networkhttps://string-db.org/network/134287.A35E_003445,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hyd [...]
lnt protein networkhttps://string-db.org/network/134287.A35E_00346Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrol [...]
rpmE protein networkhttps://string-db.org/network/134287.A35E_00347Ribosomal protein L31; Binds the 23S rRNA.
priA protein networkhttps://string-db.org/network/134287.A35E_00348Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA [...]
A35E_00349 protein networkhttps://string-db.org/network/134287.A35E_00349Nicotinate-nucleotide pyrophosphorylase (carboxylating); PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicot [...]
serC protein networkhttps://string-db.org/network/134287.A35E_00351Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreon [...]
A35E_00352 protein networkhttps://string-db.org/network/134287.A35E_003526-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
ybeY protein networkhttps://string-db.org/network/134287.A35E_00353Metalloprotein, YbeY/UPF0054 family; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
A35E_00354 protein networkhttps://string-db.org/network/134287.A35E_00354Folate-binding protein YgfZ; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act [...]
map protein networkhttps://string-db.org/network/134287.A35E_00355Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and [...]
A35E_00356 protein networkhttps://string-db.org/network/134287.A35E_00356Putative transcriptional regulator, BolA superfamily; PFAM: BolA-like protein; Belongs to the BolA/IbaG family.
murA protein networkhttps://string-db.org/network/134287.A35E_00357UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
pfkA protein networkhttps://string-db.org/network/134287.A35E_003596-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
zapB protein networkhttps://string-db.org/network/134287.A35E_00360Hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating [...]
A35E_00361 protein networkhttps://string-db.org/network/134287.A35E_00361Mismatch repair ATPase (MutS family); PFAM: MutS domain V.
glyA protein networkhttps://string-db.org/network/134287.A35E_00364Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the [...]
ispF protein networkhttps://string-db.org/network/134287.A35E_003662-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
ispD protein networkhttps://string-db.org/network/134287.A35E_003672-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to [...]
ihfA protein networkhttps://string-db.org/network/134287.A35E_00368Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tr [...]
pheT protein networkhttps://string-db.org/network/134287.A35E_00369phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthe [...]
pheS protein networkhttps://string-db.org/network/134287.A35E_00370phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha s [...]
rplT protein networkhttps://string-db.org/network/134287.A35E_00371Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing function [...]
rpmI protein networkhttps://string-db.org/network/134287.A35E_00372PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
thrS protein networkhttps://string-db.org/network/134287.A35E_00374threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor en [...]
aroK protein networkhttps://string-db.org/network/134287.A35E_00375Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
rpoD protein networkhttps://string-db.org/network/134287.A35E_00376RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma fac [...]
dnaG protein networkhttps://string-db.org/network/134287.A35E_00377DNA primase, catalytic core; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpsU protein networkhttps://string-db.org/network/134287.A35E_00378PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
A35E_00379 protein networkhttps://string-db.org/network/134287.A35E_00379PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family.
A35E_00380 protein networkhttps://string-db.org/network/134287.A35E_00380Ferritin-like protein; Iron-storage protein.
A35E_00381 protein networkhttps://string-db.org/network/134287.A35E_00381Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphat [...]
ribH protein networkhttps://string-db.org/network/134287.A35E_003826,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
nusB protein networkhttps://string-db.org/network/134287.A35E_00383NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the rib [...]
rne protein networkhttps://string-db.org/network/134287.A35E_00384Ribonuclease, Rne/Rng family; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in t [...]
csrA protein networkhttps://string-db.org/network/134287.A35E_00385Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from ra [...]
alaS protein networkhttps://string-db.org/network/134287.A35E_00386alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
secA protein networkhttps://string-db.org/network/134287.A35E_00387Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to [...]
A35E_00388 protein networkhttps://string-db.org/network/134287.A35E_00388PFAM: Protein of unknown function (DUF721).
lpxC protein networkhttps://string-db.org/network/134287.A35E_00389UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed st [...]
ftsZ protein networkhttps://string-db.org/network/134287.A35E_00390Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
ftsA protein networkhttps://string-db.org/network/134287.A35E_00391Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
A35E_00392 protein networkhttps://string-db.org/network/134287.A35E_00392PFAM: Cell division protein FtsQ.
A35E_00393 protein networkhttps://string-db.org/network/134287.A35E_00393Cell division septal protein; Essential cell division protein.
murC protein networkhttps://string-db.org/network/134287.A35E_00394UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
murG protein networkhttps://string-db.org/network/134287.A35E_00395Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
A35E_00396 protein networkhttps://string-db.org/network/134287.A35E_00396Bacterial cell division membrane protein; PFAM: Cell cycle protein; Belongs to the SEDS family.
murD protein networkhttps://string-db.org/network/134287.A35E_00397UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF [...]
mraY protein networkhttps://string-db.org/network/134287.A35E_00398Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...]
murF protein networkhttps://string-db.org/network/134287.A35E_00399UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of mure [...]
murE protein networkhttps://string-db.org/network/134287.A35E_00400UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of b [...]
A35E_00401 protein networkhttps://string-db.org/network/134287.A35E_00401Cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain.
A35E_00402 protein networkhttps://string-db.org/network/134287.A35E_00402Cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin-binding Protein dimerisation domain.
A35E_00403 protein networkhttps://string-db.org/network/134287.A35E_00403Hypothetical protein.
rsmH protein networkhttps://string-db.org/network/134287.A35E_00404S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
A35E_00405 protein networkhttps://string-db.org/network/134287.A35E_00405Ribosomal RNA small subunit methyltransferase RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
gpt protein networkhttps://string-db.org/network/134287.A35E_00406PRPP-binding protein, adenine/guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. [...]
grpE protein networkhttps://string-db.org/network/134287.A35E_00408Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with [...]
bamE protein networkhttps://string-db.org/network/134287.A35E_00410Small protein A (tmRNA-binding); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
A35E_00412 protein networkhttps://string-db.org/network/134287.A35E_00412Hypothetical protein; PFAM: SlyX.
queF protein networkhttps://string-db.org/network/134287.A35E_004137-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
pyrG protein networkhttps://string-db.org/network/134287.A35E_00414CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the fo [...]
eno protein networkhttps://string-db.org/network/134287.A35E_00415Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
queE protein networkhttps://string-db.org/network/134287.A35E_00416Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to [...]
A35E_00417 protein networkhttps://string-db.org/network/134287.A35E_00417Queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.
dnaQ protein networkhttps://string-db.org/network/134287.A35E_00418DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing func [...]
A35E_00419 protein networkhttps://string-db.org/network/134287.A35E_00419ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter transmembrane region; ABC transporter.
A35E_00420 protein networkhttps://string-db.org/network/134287.A35E_00420ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter; ABC transporter transmembrane region.
rpiA protein networkhttps://string-db.org/network/134287.A35E_00421Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
pdxB protein networkhttps://string-db.org/network/134287.A35E_00422Phosphoglycerate dehydrogenase-like oxidoreductase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
A35E_00423 protein networkhttps://string-db.org/network/134287.A35E_00423PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit.
A35E_00424 protein networkhttps://string-db.org/network/134287.A35E_00424Arabinose efflux permease family protein; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; Multidrug resistance protein.
metG protein networkhttps://string-db.org/network/134287.A35E_00425methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
A35E_00426 protein networkhttps://string-db.org/network/134287.A35E_00426Outer membrane protein (porin); PFAM: Gram-negative porin.
rnhA protein networkhttps://string-db.org/network/134287.A35E_00427Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
truA protein networkhttps://string-db.org/network/134287.A35E_00428Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
recC protein networkhttps://string-db.org/network/134287.A35E_00429DNA helicase/exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and proce [...]
A35E_00430 protein networkhttps://string-db.org/network/134287.A35E_00430DNA polymerase III, subunit gamma/tau; PFAM: ATPase family associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; DNA polymerase III tau subunit [...]
A35E_00431 protein networkhttps://string-db.org/network/134287.A35E_00431TIGRFAM: haloacid dehalogenase superfamily, subfamily IF hydrolase, YfhB.
A35E_00432 protein networkhttps://string-db.org/network/134287.A35E_00432Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehyd [...]
A35E_00433 protein networkhttps://string-db.org/network/134287.A35E_00433PFAM: NAD dependent epimerase/dehydratase family.
A35E_00434 protein networkhttps://string-db.org/network/134287.A35E_00434Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth).
glnS protein networkhttps://string-db.org/network/134287.A35E_00435PFAM: tRNA synthetases class I (E and Q), catalytic domain; tRNA synthetases class I (E and Q), anti-codon binding domain; TIGRFAM: glutaminyl-tRNA synthetase.
ackA protein networkhttps://string-db.org/network/134287.A35E_00436Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
A35E_00437 protein networkhttps://string-db.org/network/134287.A35E_00437Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
ppa protein networkhttps://string-db.org/network/134287.A35E_00438Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
minE protein networkhttps://string-db.org/network/134287.A35E_00439Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensu [...]
A35E_00440 protein networkhttps://string-db.org/network/134287.A35E_00440PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: septum site-determining protein MinD.
minC protein networkhttps://string-db.org/network/134287.A35E_00441Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments tha [...]
tusD protein networkhttps://string-db.org/network/134287.A35E_00442Sulfur relay protein TusD/DsrE; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and [...]
A35E_00443 protein networkhttps://string-db.org/network/134287.A35E_00443PFAM: DsrE/DsrF-like family; TIGRFAM: sulfur relay protein TusC/DsrF; Belongs to the DsrF/TusC family.
tusB protein networkhttps://string-db.org/network/134287.A35E_00444Sulfur relay protein TusB/DsrH; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
rpsL protein networkhttps://string-db.org/network/134287.A35E_00445Ribosomal protein S12, bacterial/organelle; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interf [...]
rpsG protein networkhttps://string-db.org/network/134287.A35E_00446Ribosomal protein S7, bacterial/organelle; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at [...]
fusA protein networkhttps://string-db.org/network/134287.A35E_00447Translation elongation factor EF-G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PR [...]
tuf protein networkhttps://string-db.org/network/134287.A35E_00448Translation elongation factor TU; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
rppH protein networkhttps://string-db.org/network/134287.A35E_00449NTP pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can [...]
A35E_00450 protein networkhttps://string-db.org/network/134287.A35E_00450Phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III [...]
lpxH protein networkhttps://string-db.org/network/134287.A35E_00451UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water [...]
A35E_00452 protein networkhttps://string-db.org/network/134287.A35E_00452PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
mnmA protein networkhttps://string-db.org/network/134287.A35E_00453tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of [...]
rplM protein networkhttps://string-db.org/network/134287.A35E_00454Ribosomal protein L13, bacterial type; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the [...]
rpsI protein networkhttps://string-db.org/network/134287.A35E_00455PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family.
fmt protein networkhttps://string-db.org/network/134287.A35E_00457methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
def protein networkhttps://string-db.org/network/134287.A35E_00458Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
A35E_00460 protein networkhttps://string-db.org/network/134287.A35E_00460PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
tsaC protein networkhttps://string-db.org/network/134287.A35E_00461Putative translation factor (SUA5); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the c [...]
bamB protein networkhttps://string-db.org/network/134287.A35E_00462Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
A35E_00463 protein networkhttps://string-db.org/network/134287.A35E_00463Hypothetical protein.
hisS protein networkhttps://string-db.org/network/134287.A35E_00464PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase.
ispG protein networkhttps://string-db.org/network/134287.A35E_004651-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG [...]
A35E_00466 protein networkhttps://string-db.org/network/134287.A35E_00466Hypothetical protein.
rlmN protein networkhttps://string-db.org/network/134287.A35E_0046723S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the [...]
A35E_00468 protein networkhttps://string-db.org/network/134287.A35E_00468PFAM: Protein of unknown function (DUF493); Belongs to the UPF0250 family.
lipB protein networkhttps://string-db.org/network/134287.A35E_00469Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can al [...]
lipA protein networkhttps://string-db.org/network/134287.A35E_00470Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, ther [...]
gmhA protein networkhttps://string-db.org/network/134287.A35E_00471Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
A35E_00472 protein networkhttps://string-db.org/network/134287.A35E_00472PFAM: 'Cold-shock' DNA-binding domain.
efp protein networkhttps://string-db.org/network/134287.A35E_00473Translation elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, [...]
ddl protein networkhttps://string-db.org/network/134287.A35E_00476D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
A35E_00477 protein networkhttps://string-db.org/network/134287.A35E_00477PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
A35E_00478 protein networkhttps://string-db.org/network/134287.A35E_00478Membrane protein TerC, possibly involved in tellurium resistance; PFAM: Integral membrane protein TerC family.
ispH protein networkhttps://string-db.org/network/134287.A35E_00479(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and d [...]
lspA protein networkhttps://string-db.org/network/134287.A35E_00480Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
ileS protein networkhttps://string-db.org/network/134287.A35E_00481Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
A35E_00482 protein networkhttps://string-db.org/network/134287.A35E_00482PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family.
A35E_00483 protein networkhttps://string-db.org/network/134287.A35E_00483Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
A35E_00484 protein networkhttps://string-db.org/network/134287.A35E_00484Zn-dependent oxidoreductase, NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
folE protein networkhttps://string-db.org/network/134287.A35E_00485PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
cca protein networkhttps://string-db.org/network/134287.A35E_00486tRNA nucleotidyltransferase/poly(A) polymerase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucle [...]
yqgF protein networkhttps://string-db.org/network/134287.A35E_00488RNAse H-fold protein YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
A35E_00489 protein networkhttps://string-db.org/network/134287.A35E_00489Putative transcriptional regulator; PFAM: Uncharacterized ACR, COG1678.
gshB protein networkhttps://string-db.org/network/134287.A35E_00490PFAM: Prokaryotic glutathione synthetase, N-terminal domain; Prokaryotic glutathione synthetase, ATP-grasp domain; TIGRFAM: glutathione synthetase, prokaryotic; Belongs to the prokaryotic GSH syn [...]
zipA protein networkhttps://string-db.org/network/134287.A35E_00491Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also req [...]
A35E_00492 protein networkhttps://string-db.org/network/134287.A35E_00492PFAM: Inositol monophosphatase family.
A35E_00495 protein networkhttps://string-db.org/network/134287.A35E_00495D,D-heptose 1,7-bisphosphate phosphatase; PFAM: Polynucleotide kinase 3 phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosp [...]
rpsB protein networkhttps://string-db.org/network/134287.A35E_00496PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/134287.A35E_00497Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis [...]
pyrH protein networkhttps://string-db.org/network/134287.A35E_00498Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
frr protein networkhttps://string-db.org/network/134287.A35E_00499Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
dxr protein networkhttps://string-db.org/network/134287.A35E_005001-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).
uppS protein networkhttps://string-db.org/network/134287.A35E_00501Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,3 [...]
A35E_00502 protein networkhttps://string-db.org/network/134287.A35E_00502CDP-diglyceride synthetase; PFAM: Cytidylyltransferase family.
A35E_00503 protein networkhttps://string-db.org/network/134287.A35E_00503RIP metalloprotease RseP; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP.
bamA protein networkhttps://string-db.org/network/134287.A35E_00504Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer memb [...]
A35E_00505 protein networkhttps://string-db.org/network/134287.A35E_00505PFAM: Outer membrane protein (OmpH-like); Belongs to the skp family.
lpxD protein networkhttps://string-db.org/network/134287.A35E_00506UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved [...]
fabZ protein networkhttps://string-db.org/network/134287.A35E_00507Beta-hydroxyacyl-(acyl carrier protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated [...]
lpxA protein networkhttps://string-db.org/network/134287.A35E_00508acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer memb [...]
lpxB protein networkhttps://string-db.org/network/134287.A35E_00509lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid t [...]
A35E_00510 protein networkhttps://string-db.org/network/134287.A35E_00510PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc).
accA protein networkhttps://string-db.org/network/134287.A35E_00511acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its c [...]
dksA protein networkhttps://string-db.org/network/134287.A35E_00512Transcriptional regulator, TraR/DksA family; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regu [...]
A35E_00513 protein networkhttps://string-db.org/network/134287.A35E_00513Metalloendopeptidase-like membrane protein; PFAM: Peptidase family M23; LysM domain.
tadA protein networkhttps://string-db.org/network/134287.A35E_00514Cytosine/adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
topA protein networkhttps://string-db.org/network/134287.A35E_00515DNA topoisomerase I, bacterial; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one [...]
lgt protein networkhttps://string-db.org/network/134287.A35E_00516Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
A35E_00517 protein networkhttps://string-db.org/network/134287.A35E_00517PFAM: PTS system fructose IIA component; PTS system sorbose subfamily IIB component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component; PTS system, mannose/fructose/sorbose fami [...]
A35E_00518 protein networkhttps://string-db.org/network/134287.A35E_00518PFAM: PTS system sorbose-specific iic component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC component.
A35E_00519 protein networkhttps://string-db.org/network/134287.A35E_00519PFAM: PTS system mannose/fructose/sorbose family IID component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IID component.
yajC protein networkhttps://string-db.org/network/134287.A35E_00520Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into mem [...]
tgt protein networkhttps://string-db.org/network/134287.A35E_00521tRNA-guanine transglycosylase, queuosine-34-forming; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon [...]
coaA protein networkhttps://string-db.org/network/134287.A35E_00522PFAM: Phosphoribulokinase / Uridine kinase family; TIGRFAM: pantothenate kinase, bacterial type.
A35E_00523 protein networkhttps://string-db.org/network/134287.A35E_00523PFAM: Domain of unknown function (DUF3458); Peptidase family M1; TIGRFAM: aminopeptidase N, Escherichia coli type.
A35E_00524 protein networkhttps://string-db.org/network/134287.A35E_00524PFAM: Predicted permease; TIGRFAM: lipoprotein releasing system, transmembrane protein LolE; lipoprotein releasing system, transmembrane protein, LolC/E family.
lolD protein networkhttps://string-db.org/network/134287.A35E_00525Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
A35E_00526 protein networkhttps://string-db.org/network/134287.A35E_00526PFAM: Predicted permease; TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family.
mfd protein networkhttps://string-db.org/network/134287.A35E_00527Transcription-repair coupling factor Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncate [...]
lolA protein networkhttps://string-db.org/network/134287.A35E_00528Periplasmic chaperone LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-ter [...]
serS protein networkhttps://string-db.org/network/134287.A35E_00529seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
udk protein networkhttps://string-db.org/network/134287.A35E_00531PFAM: Phosphoribulokinase / Uridine kinase family; TIGRFAM: uridine kinase.
rep protein networkhttps://string-db.org/network/134287.A35E_00532ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded [...]
A35E_00533 protein networkhttps://string-db.org/network/134287.A35E_00533PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.
slyA protein networkhttps://string-db.org/network/134287.A35E_00534Transcriptional regulator; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.
der protein networkhttps://string-db.org/network/134287.A35E_00536Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA [...]
A35E_00537 protein networkhttps://string-db.org/network/134287.A35E_00537Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein; PFAM: short chain dehydrogenase.
trmB protein networkhttps://string-db.org/network/134287.A35E_00538tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB f [...]
A35E_00540 protein networkhttps://string-db.org/network/134287.A35E_00540Single stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of act [...]
A35E_00541 protein networkhttps://string-db.org/network/134287.A35E_00541PFAM: Stringent starvation protein B.
A35E_00542 protein networkhttps://string-db.org/network/134287.A35E_00542PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase.
A35E_00543 protein networkhttps://string-db.org/network/134287.A35E_00543PFAM: Exonuclease; Exonuclease C-terminal.
A35E_00544 protein networkhttps://string-db.org/network/134287.A35E_00544PFAM: Ribonucleotide reductase, small chain.
A35E_00545 protein networkhttps://string-db.org/network/134287.A35E_00545Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [...]
rpsT protein networkhttps://string-db.org/network/134287.A35E_00546Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
A35E_00548 protein networkhttps://string-db.org/network/134287.A35E_00548A/G-specific DNA glycosylase; PFAM: HhH-GPD superfamily base excision DNA repair protein; TIGRFAM: A/G-specific adenine glycosylase.
A35E_00549 protein networkhttps://string-db.org/network/134287.A35E_00549A/G-specific DNA glycosylase; Adenine glycosylase active on G-A mispairs.
A35E_00550 protein networkhttps://string-db.org/network/134287.A35E_00550Fe-S cluster protector protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic en [...]
A35E_00551 protein networkhttps://string-db.org/network/134287.A35E_00551Soluble lytic murein transglycosylase-like protein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
tig protein networkhttps://string-db.org/network/134287.A35E_00552Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs t [...]
lpxK protein networkhttps://string-db.org/network/134287.A35E_00553lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-pho [...]
msbA protein networkhttps://string-db.org/network/134287.A35E_00554Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) [...]
gshA protein networkhttps://string-db.org/network/134287.A35E_00558PFAM: Glutamate-cysteine ligase; TIGRFAM: glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
A35E_00559 protein networkhttps://string-db.org/network/134287.A35E_00559Periplasmic serine protease, Do/DeqQ family; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family; Belongs to the peptidase S1C family.
A35E_00560 protein networkhttps://string-db.org/network/134287.A35E_00560PFAM: Bacterial regulatory proteins, tetR family.
dut protein networkhttps://string-db.org/network/134287.A35E_00561Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the int [...]
A35E_00562 protein networkhttps://string-db.org/network/134287.A35E_00562Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantot [...]
A35E_00563 protein networkhttps://string-db.org/network/134287.A35E_00563PFAM: Uracil DNA glycosylase superfamily; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
A35E_00564 protein networkhttps://string-db.org/network/134287.A35E_00564Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the u [...]
A35E_00565 protein networkhttps://string-db.org/network/134287.A35E_00565PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
A35E_00566 protein networkhttps://string-db.org/network/134287.A35E_00566Parvulin-like peptidyl-prolyl isomerase; PFAM: PPIC-type PPIASE domain.
A35E_00568 protein networkhttps://string-db.org/network/134287.A35E_00568PFAM: NlpB/DapX lipoprotein.
gyrB protein networkhttps://string-db.org/network/134287.A35E_00569DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
A35E_00570 protein networkhttps://string-db.org/network/134287.A35E_00570Flavodoxin, long chain; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
rpmF protein networkhttps://string-db.org/network/134287.A35E_00571PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
plsX protein networkhttps://string-db.org/network/134287.A35E_00572Phosphate:acyl-(acyl carrier protein) acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-AC [...]
fabH protein networkhttps://string-db.org/network/134287.A35E_005733-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first [...]
A35E_00574 protein networkhttps://string-db.org/network/134287.A35E_00574PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
A35E_00575 protein networkhttps://string-db.org/network/134287.A35E_005753-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cy [...]
acpP protein networkhttps://string-db.org/network/134287.A35E_00576Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
A35E_00577 protein networkhttps://string-db.org/network/134287.A35E_00577Hypothetical protein.
A35E_00578 protein networkhttps://string-db.org/network/134287.A35E_00578Hypothetical protein.
A35E_00579 protein networkhttps://string-db.org/network/134287.A35E_00579Hypothetical protein.
fabA protein networkhttps://string-db.org/network/134287.A35E_00580Beta-hydroxyacyl-(acyl carrier protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-de [...]
mtnN protein networkhttps://string-db.org/network/134287.A35E_005815''-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy [...]
zwf protein networkhttps://string-db.org/network/134287.A35E_00582Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
A35E_00583 protein networkhttps://string-db.org/network/134287.A35E_00583PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
A35E_00584 protein networkhttps://string-db.org/network/134287.A35E_00584Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
greA protein networkhttps://string-db.org/network/134287.A35E_00585Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a [...]
rlmE protein networkhttps://string-db.org/network/134287.A35E_0058623S rRNA methylase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
ftsH protein networkhttps://string-db.org/network/134287.A35E_00587ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane [...]
A35E_00588 protein networkhttps://string-db.org/network/134287.A35E_00588PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase.
A35E_00589 protein networkhttps://string-db.org/network/134287.A35E_00589Dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase.
glmM protein networkhttps://string-db.org/network/134287.A35E_00590Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
A35E_00591 protein networkhttps://string-db.org/network/134287.A35E_00591Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
rimP protein networkhttps://string-db.org/network/134287.A35E_00594Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
nusA protein networkhttps://string-db.org/network/134287.A35E_00595Transcription termination factor NusA; Participates in both transcription termination and antitermination.
infB protein networkhttps://string-db.org/network/134287.A35E_00596Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
rbfA protein networkhttps://string-db.org/network/134287.A35E_00597Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
truB protein networkhttps://string-db.org/network/134287.A35E_00598tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
pnp protein networkhttps://string-db.org/network/134287.A35E_00600Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
deaD protein networkhttps://string-db.org/network/134287.A35E_00601DNA/RNA helicase, superfamily II; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
A35E_00602 protein networkhttps://string-db.org/network/134287.A35E_00602Hydrolase, TatD family; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family.
A35E_00603 protein networkhttps://string-db.org/network/134287.A35E_00603PFAM: DNA polymerase III, delta subunit, C terminal; TIGRFAM: DNA polymerase III, delta' subunit.
tmk protein networkhttps://string-db.org/network/134287.A35E_00604Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
rnb protein networkhttps://string-db.org/network/134287.A35E_00605Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
rpoZ protein networkhttps://string-db.org/network/134287.A35E_00606DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and al [...]
gmk protein networkhttps://string-db.org/network/134287.A35E_00607Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
prfA protein networkhttps://string-db.org/network/134287.A35E_00608Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
prmC protein networkhttps://string-db.org/network/134287.A35E_00609protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally [...]
queA protein networkhttps://string-db.org/network/134287.A35E_00610S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ [...]
A35E_00611 protein networkhttps://string-db.org/network/134287.A35E_00611GTP-binding protein TypA/BipA; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-bind [...]
clpP protein networkhttps://string-db.org/network/134287.A35E_00612ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the d [...]
clpX protein networkhttps://string-db.org/network/134287.A35E_00613Endopeptidase Clp ATP-binding regulatory subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in [...]
lon protein networkhttps://string-db.org/network/134287.A35E_00614ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for [...]
A35E_00615 protein networkhttps://string-db.org/network/134287.A35E_00615Cysteine desulfurase family protein; PFAM: Aminotransferase class-V.
A35E_00616 protein networkhttps://string-db.org/network/134287.A35E_00616Transcriptional regulator, BadM/Rrf2 family; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
erpA protein networkhttps://string-db.org/network/134287.A35E_00622Hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG.
A35E_00623 protein networkhttps://string-db.org/network/134287.A35E_00623PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs [...]
A35E_00624 protein networkhttps://string-db.org/network/134287.A35E_00624Hypothetical protein.
plsB protein networkhttps://string-db.org/network/134287.A35E_00625PFAM: Acyltransferase; TIGRFAM: glycerol-3-phosphate O-acyltransferase; Belongs to the GPAT/DAPAT family.
nfuA protein networkhttps://string-db.org/network/134287.A35E_00626Hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Coul [...]