Organism Overview: Clostridium bornimense


 
dnaA protein networkhttps://string-db.org/network/1216932.CM240_0001Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically doub [...]
dnaN protein networkhttps://string-db.org/network/1216932.CM240_0002DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadin [...]
CDM67201.1 protein networkhttps://string-db.org/network/1216932.CM240_0003S4 domain-containing protein; Family membership.
recF protein networkhttps://string-db.org/network/1216932.CM240_0004DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-strand [...]
CDM67203.1 protein networkhttps://string-db.org/network/1216932.CM240_0005Hypothetical protein; Family membership.
gyrB1 protein networkhttps://string-db.org/network/1216932.CM240_0006DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
gyrA protein networkhttps://string-db.org/network/1216932.CM240_0007DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
CDM67206.1 protein networkhttps://string-db.org/network/1216932.CM240_0013Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope,biogenesis, outer membrane]; High confidence in function and specificity.
CDM67207.1 protein networkhttps://string-db.org/network/1216932.CM240_0014Hypothetical protein.
CDM67208.1 protein networkhttps://string-db.org/network/1216932.CM240_0015Putative protein; Family membership.
CDM67209.1 protein networkhttps://string-db.org/network/1216932.CM240_0016Transcriptional regulator; High confidence in function and specificity.
CDM67210.1 protein networkhttps://string-db.org/network/1216932.CM240_0017UPF0182 protein; High confidence in function and specificity.
CDM67211.1 protein networkhttps://string-db.org/network/1216932.CM240_0018In molecular biology, the FAD dependent oxidoreductase family of proteins is a family of FAD dependent oxidoreductases.This entry includes various FAD dependent oxidoreductases: Glycerol-3-phosph [...]
CDM67212.1 protein networkhttps://string-db.org/network/1216932.CM240_0019Hypothetical protein.
serS protein networkhttps://string-db.org/network/1216932.CM240_0020Serine-tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further con [...]
CDM67214.1 protein networkhttps://string-db.org/network/1216932.CM240_0021Heavy metal translocating P-type ATPase; Heavy-metal-associated domain (HMA) is a conserved,domain of approximately 30 amino acid residues found in a,number of proteins that transport or detoxify [...]
CDM67215.1 protein networkhttps://string-db.org/network/1216932.CM240_0022Putative membrane protein.
CDM67216.1 protein networkhttps://string-db.org/network/1216932.CM240_0023This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conser [...]
CDM67217.1 protein networkhttps://string-db.org/network/1216932.CM240_0027GNAT family acetyltransferase; The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions f [...]
CDM67218.1 protein networkhttps://string-db.org/network/1216932.CM240_0029Hypothetical protein; Family membership.
CDM67219.1 protein networkhttps://string-db.org/network/1216932.CM240_0030Putative membrane protein.
CDM67220.1 protein networkhttps://string-db.org/network/1216932.CM240_0031Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; This entry represents various Fe-S type hydro-lyases, including the alpha subunit from both L-tartrate dehydratase and class 1 [...]
CDM67221.1 protein networkhttps://string-db.org/network/1216932.CM240_0032Fumarate hydratase; Provisional; High confidence in function and specificity.
CDM67222.1 protein networkhttps://string-db.org/network/1216932.CM240_0033Malic enzymes (malate oxidoreductases) catalyse the oxidative decarboxylation of malate to form pyruvate [PUBMED:], a reaction important in a number of metabolic pathways -e.g. carbon dioxide rel [...]
CDM67223.1 protein networkhttps://string-db.org/network/1216932.CM240_0034Putative protein.
CDM67224.1 protein networkhttps://string-db.org/network/1216932.CM240_0035Hypothetical protein; High confidence in function and specificity.
pncB protein networkhttps://string-db.org/network/1216932.CM240_0036Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and [...]
psd1 protein networkhttps://string-db.org/network/1216932.CM240_0037Phosphatidylserine decarboxylase proenzyme 1; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
CDM67227.1 protein networkhttps://string-db.org/network/1216932.CM240_0038TetR family transcriptional regulator; This entry represents a DNA-binding domain with a helix-turn-helix (HTH) structure that is found in several bacterial and archaeal transcriptional regulator [...]
tadA protein networkhttps://string-db.org/network/1216932.CM240_0040Cytidine/deoxycytidylate deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
CDM67229.1 protein networkhttps://string-db.org/network/1216932.CM240_0041Putative protein; Family membership.
CDM67230.1 protein networkhttps://string-db.org/network/1216932.CM240_0042Transcriptional regulator, AbrB family; Family membership.
CDM67231.1 protein networkhttps://string-db.org/network/1216932.CM240_0043ABC transporter, substrate-binding protein; ABC-type metal ion transport system,periplasmic,component/surface adhesin [Inorganic ion transport and,metabolism; High confidence in function and spec [...]
dnaX protein networkhttps://string-db.org/network/1216932.CM240_0045DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' t [...]
CDM67233.1 protein networkhttps://string-db.org/network/1216932.CM240_0046Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
recR protein networkhttps://string-db.org/network/1216932.CM240_0047Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
CDM67235.1 protein networkhttps://string-db.org/network/1216932.CM240_0048Hypothetical protein.
CDM67236.1 protein networkhttps://string-db.org/network/1216932.CM240_0049Hypothetical protein; Frameshift.
CDM67237.1 protein networkhttps://string-db.org/network/1216932.CM240_0054Hypothetical protein; Family membership.
CDM67238.1 protein networkhttps://string-db.org/network/1216932.CM240_0055Putative membrane protein; Family membership.
CDM67239.1 protein networkhttps://string-db.org/network/1216932.CM240_0056Putative membrane protein.
CDM67240.1 protein networkhttps://string-db.org/network/1216932.CM240_0057Aminotransferase, class V; Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes,such as the covalent binding of the pyridoxal-phosphate group to a [...]
trpB1 protein networkhttps://string-db.org/network/1216932.CM240_0062Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
CDM67242.1 protein networkhttps://string-db.org/network/1216932.CM240_0063Alkyl hydroperoxide reductase (AhpC) is responsible for directly reducing organic hyperoxides in its reduced dithiol form. Thiol specific antioxidant (TSA) is a physiologically important antioxid [...]
CDM67243.1 protein networkhttps://string-db.org/network/1216932.CM240_0064Stage V sporulation protein B; Members of this family are integral membrane proteins [1]. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part [...]
aroF protein networkhttps://string-db.org/network/1216932.CM240_0065This model describes one of at least three types of phospho-2-dehydro-3-deoxyheptonate aldolase (DAHP synthase). This enzyme catalyzes the first of 7 steps in the biosynthesis of chorismate, that [...]
tyrA protein networkhttps://string-db.org/network/1216932.CM240_0066Members of this family are prephenate dehydrogenasesinvolved in tyrosine biosynthesis; High confidence in function and specificity.
aroB protein networkhttps://string-db.org/network/1216932.CM240_00673-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
aroA1 protein networkhttps://string-db.org/network/1216932.CM240_00683-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
aroC protein networkhttps://string-db.org/network/1216932.CM240_0069Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
CDM67249.1 protein networkhttps://string-db.org/network/1216932.CM240_0070Chorismate mutase; All the other members of this clade are mono-functional. Members of this clade from Streptococcus and Lactococcus have been found which represent the sole chorismate mutase dom [...]
aroK protein networkhttps://string-db.org/network/1216932.CM240_0071Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
aroQ protein networkhttps://string-db.org/network/1216932.CM240_00723-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
CDM67252.1 protein networkhttps://string-db.org/network/1216932.CM240_0073Hypothetical protein; Family membership.
CDM67253.1 protein networkhttps://string-db.org/network/1216932.CM240_0074Hypothetical protein; Family membership.
CDM67254.1 protein networkhttps://string-db.org/network/1216932.CM240_0075Hypothetical protein; High confidence in function and specificity.
CDM67255.1 protein networkhttps://string-db.org/network/1216932.CM240_0076Hypothetical protein; High confidence in function and specificity.
CDM67256.1 protein networkhttps://string-db.org/network/1216932.CM240_0077Proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues. The best studied of these proteins is the prokaryotic catabolite gene activator (also known a [...]
CDM67257.1 protein networkhttps://string-db.org/network/1216932.CM240_0078Hypothetical protein.
exoA protein networkhttps://string-db.org/network/1216932.CM240_0079Exodeoxyribonuclease; This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling; High confidence in function [...]
rnz protein networkhttps://string-db.org/network/1216932.CM240_0080Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs [...]
CDM67260.1 protein networkhttps://string-db.org/network/1216932.CM240_0081N-acetyltransferase GCN5; N-Acyltransferase superfamily: Various enzymes that,characteristically catalyze the transfer of an acyl group,to a substrate; High confidence in function and specificity [...]
CDM67261.1 protein networkhttps://string-db.org/network/1216932.CM240_0082Hypothetical protein; Family membership.
braG protein networkhttps://string-db.org/network/1216932.CM240_0083High-affinity branched-chain amino acid transport ATP-binding protein BraG; Component of the high affinity leucine,isoleucine,valine, transport system (LIV-I), which is operative without Na+ and [...]
livG protein networkhttps://string-db.org/network/1216932.CM240_0084High-affinity branched-chain amino acid transport ATP-binding protein LivG; High confidence in function and specificity.
CDM67264.1 protein networkhttps://string-db.org/network/1216932.CM240_0085Transposase and inactivated derivatives [DNA,replication, recombination, and repair]; High confidence in function and specificity.
CDM67265.1 protein networkhttps://string-db.org/network/1216932.CM240_0086HAAT family amino acid/amide ABC transporter membrane protein 2; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH P08340 [...]
CDM67266.1 protein networkhttps://string-db.org/network/1216932.CM240_0087Inner-membrane translocator; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH P08340 and LivM P22729 both of which are fo [...]
CDM67267.1 protein networkhttps://string-db.org/network/1216932.CM240_0088Extracellular ligand-binding receptor; Leu/Ile/Val/Thr-and Leu-binding proteins, which share a high degree of sequence similarity, are components of the leucine-specific transport system. This is [...]
CDM67268.1 protein networkhttps://string-db.org/network/1216932.CM240_0089Isopentenyl-diphosphate delta-isomerase.
CDM67269.1 protein networkhttps://string-db.org/network/1216932.CM240_0090M6 family metalloprotease domain; TIGR03296; High confidence in function and specificity.
CDM67270.1 protein networkhttps://string-db.org/network/1216932.CM240_0091Dockerin type 1; Dockerin is a protein domain found in the cellulosome cellular structure. It is found on many endoglucanase enzymes. The dockerin's binding partner is the cohesin domain, located [...]
CDM67271.1 protein networkhttps://string-db.org/network/1216932.CM240_0092Sensor histidine kinase/response regulator; Signal transduction histidine kinase [Signal transduction mechanisms]; Family membership.
CDM67272.1 protein networkhttps://string-db.org/network/1216932.CM240_0093Bacterial regulatory proteins, tetR family;,pfam00440; High confidence in function and specificity.
CDM67273.1 protein networkhttps://string-db.org/network/1216932.CM240_0094Aminopeptidase, M42 family; These peptidases are found in Archaea and Bacteria. The example in Lactococcus lactis, PepA, aids growth on milk [1]. Pyrococcus horikoshii contain a thermostable de-b [...]
CDM67274.1 protein networkhttps://string-db.org/network/1216932.CM240_0095Hypothetical protein; Family membership.
CDM67275.1 protein networkhttps://string-db.org/network/1216932.CM240_0096VTC domain-containing protein; This presumed domain is found in the yeast vacuolar transport chaperone proteins VTC2, VTC3 and VTC4. This domain is also found in a variety of bacterial proteins; [...]
CDM67276.1 protein networkhttps://string-db.org/network/1216932.CM240_0097Hypothetical protein; Family membership.
CDM67277.1 protein networkhttps://string-db.org/network/1216932.CM240_0098Aminoglycoside 3'-phosphotransferase (APH) and,Choline Kinase (ChoK) family. The APH/ChoK family is part, of a larger superfamily that includes the catalytic,domains of other kinases, such as the [...]
CDM67278.1 protein networkhttps://string-db.org/network/1216932.CM240_0099eamA-like transporter family protein; High confidence in function and specificity.
CDM67279.1 protein networkhttps://string-db.org/network/1216932.CM240_0100Haloacid dehalogenase-like hydrolases. The haloacid,dehalogenase-like (HAD) superfamily includes L-2-haloacid,dehalogenase, epoxide hydrolase,phosphoserine,phosphatase,phosphomannomutase, phospho [...]
CDM67280.1 protein networkhttps://string-db.org/network/1216932.CM240_0101Hypothetical protein; Family membership.
CDM67281.1 protein networkhttps://string-db.org/network/1216932.CM240_0102Hypothetical protein; Family membership.
CDM67282.1 protein networkhttps://string-db.org/network/1216932.CM240_0103Hypothetical protein; Family membership.
CDM67283.1 protein networkhttps://string-db.org/network/1216932.CM240_0104Hypothetical protein.
feoB protein networkhttps://string-db.org/network/1216932.CM240_0105Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) [...]
CDM67285.1 protein networkhttps://string-db.org/network/1216932.CM240_0106Hypothetical protein.
CDM67286.1 protein networkhttps://string-db.org/network/1216932.CM240_0107StbA family protein; This entry represents bacterial plasmid segregation proteins ParM and StbA. They are involved in the control of plasmid partition and required for the accurate segregation of [...]
CDM67287.1 protein networkhttps://string-db.org/network/1216932.CM240_0108Hypothetical protein; Family membership.
CDM67288.1 protein networkhttps://string-db.org/network/1216932.CM240_0109Transposase; High confidence in function and specificity.
CDM67289.1 protein networkhttps://string-db.org/network/1216932.CM240_0110Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS [...]
CDM67290.1 protein networkhttps://string-db.org/network/1216932.CM240_0111Hypothetical protein.
CDM67291.1 protein networkhttps://string-db.org/network/1216932.CM240_0112Putative protein.
CDM67292.1 protein networkhttps://string-db.org/network/1216932.CM240_0113Putative membrane protein.
CDM67293.1 protein networkhttps://string-db.org/network/1216932.CM240_0114Hypothetical protein; Family membership.
CDM67294.1 protein networkhttps://string-db.org/network/1216932.CM240_0115Hypothetical protein; Family membership.
CDM67295.1 protein networkhttps://string-db.org/network/1216932.CM240_0116Hypothetical protein; Family membership.
CDM67296.1 protein networkhttps://string-db.org/network/1216932.CM240_0117Putative membrane protein.
CDM67297.1 protein networkhttps://string-db.org/network/1216932.CM240_0118Hypothetical protein; Family membership.
CDM67299.1 protein networkhttps://string-db.org/network/1216932.CM240_0120ABC transporter, permease protein; Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two recip [...]
CDM67300.1 protein networkhttps://string-db.org/network/1216932.CM240_0121Polar amino acid ABC transporter; Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two recipr [...]
artM protein networkhttps://string-db.org/network/1216932.CM240_0122Arginine transport ATP-binding protein ArtM; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters [...]
CDM67302.1 protein networkhttps://string-db.org/network/1216932.CM240_0123ABC transporter, substrate-binding protein,family 3; Bacterial high affinity transport systems are involved in active transport of solutes across the cytoplasmic membrane. The protein components [...]
CDM67303.1 protein networkhttps://string-db.org/network/1216932.CM240_0124Putative membrane protein; Family membership.
CDM67304.1 protein networkhttps://string-db.org/network/1216932.CM240_0125Iron-containing alcohol dehydrogenase; Currently three, structurally and catalytically,different types of alcohol dehydrogenases are known:Zinc-containing 'long-chain' alcohol dehydrogenases,Inse [...]
CDM67305.1 protein networkhttps://string-db.org/network/1216932.CM240_0126SNF family Na+-dependent transporter; High confidence in function and specificity.
CDM67306.1 protein networkhttps://string-db.org/network/1216932.CM240_0127Signal peptidase I; The enzyme is found in bacterial membranes and in chloroplast thylakoid membranes. Unaffected by inhibitors of most serine peptidases, but site-directed mutagenesis implicates [...]
CDM67307.1 protein networkhttps://string-db.org/network/1216932.CM240_0128Hypothetical protein; Family membership.
CDM67308.1 protein networkhttps://string-db.org/network/1216932.CM240_0129Hypothetical protein; Family membership.
CDM67309.1 protein networkhttps://string-db.org/network/1216932.CM240_0130Putative membrane protein.
CDM67310.1 protein networkhttps://string-db.org/network/1216932.CM240_0131Putative protein.
CDM67311.1 protein networkhttps://string-db.org/network/1216932.CM240_0132Hypothetical protein; Family membership.
CDM67312.1 protein networkhttps://string-db.org/network/1216932.CM240_0133Hypothetical protein.
CDM67313.1 protein networkhttps://string-db.org/network/1216932.CM240_0134Hypothetical protein; Family membership.
CDM67314.1 protein networkhttps://string-db.org/network/1216932.CM240_0135Hypothetical protein; Family membership.
CDM67315.1 protein networkhttps://string-db.org/network/1216932.CM240_0136Hypothetical protein; Family membership.
CDM67316.1 protein networkhttps://string-db.org/network/1216932.CM240_0137PrkA proteins are bacterial and archaeal serine kinases approximately 630 residues in length; High confidence in function and specificity.
CDM67317.1 protein networkhttps://string-db.org/network/1216932.CM240_0138Hypothetical protein; High confidence in function and specificity; Belongs to the UPF0229 family.
CDM67318.1 protein networkhttps://string-db.org/network/1216932.CM240_0139SpoVR family protein; Family member P37875 is Bacillus subtilis stage V sporulation protein R, which is involved in spore cortex formation. Little is known about cortex biosynthesis,except that i [...]
asnO protein networkhttps://string-db.org/network/1216932.CM240_0140Asparagine synthetase [glutamine-hydrolyzing] 3; Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the assembly of aspa [...]
ykfA protein networkhttps://string-db.org/network/1216932.CM240_0146Peptidase U61 LD-carboxypeptidase; This entry represents the C-terminal domain of the LD-carboxypeptidase A. Muramoyl-tetrapeptide carboxypeptidase or LD-carboxypeptidase A hydrolyses a peptide b [...]
CDM67321.1 protein networkhttps://string-db.org/network/1216932.CM240_0147Magnesium transporter, CorA family; The CorA transport system is the primary Mg2+ influx system of Salmonella typhimurium and Escherichia coli. CorA is virtually ubiquitous in the Bacteria and Ar [...]
CDM67322.1 protein networkhttps://string-db.org/network/1216932.CM240_0148Hypothetical protein; Family membership.
CDM67323.1 protein networkhttps://string-db.org/network/1216932.CM240_0149Amidohydrolase; High confidence in function and specificity.
CDM67324.1 protein networkhttps://string-db.org/network/1216932.CM240_0150Hypothetical protein; Family membership.
CDM67325.1 protein networkhttps://string-db.org/network/1216932.CM240_0151Hypothetical protein; Family membership.
CDM67326.1 protein networkhttps://string-db.org/network/1216932.CM240_0152Pyridoxal-dependent decarboxylases are bacterial proteins acting on ornithine, lysine, arginine and related substrates. One of the regions of sequence similarity contains a conserved lysine resid [...]
tmk protein networkhttps://string-db.org/network/1216932.CM240_0153Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
CDM67328.1 protein networkhttps://string-db.org/network/1216932.CM240_0154Hypothetical protein; Family membership.
CDM67329.1 protein networkhttps://string-db.org/network/1216932.CM240_0155The Escherichia coli DNA polymerase III gamma complex clamp loader assembles the ring-shaped beta sliding clamp onto DNA. The core polymerase is tethered to the template by beta, enabling progres [...]
yaaT protein networkhttps://string-db.org/network/1216932.CM240_0156Stage 0 sporulation protein YaaT; Bacillus subtilis yaaT protein, which plays a significant role in phosphorelay during initiation of sporulation. It is possible that the yaaT protein is also rel [...]
CDM67331.1 protein networkhttps://string-db.org/network/1216932.CM240_0157Hypothetical protein; Family membership.
CDM67332.1 protein networkhttps://string-db.org/network/1216932.CM240_0158Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
CDM67333.1 protein networkhttps://string-db.org/network/1216932.CM240_0159This domain appears to be a methyltransferase domain; High confidence in function and specificity.
rsmI protein networkhttps://string-db.org/network/1216932.CM240_0160Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
CDM67335.1 protein networkhttps://string-db.org/network/1216932.CM240_0161NLP/P60 protein; The function of this domain is unknown. It is found in several lipoproteins; Family membership.
CDM67336.1 protein networkhttps://string-db.org/network/1216932.CM240_0162Hypothetical protein; Family membership.
CDM67337.1 protein networkhttps://string-db.org/network/1216932.CM240_0163Hypothetical protein.
CDM67338.1 protein networkhttps://string-db.org/network/1216932.CM240_0164NlpC/P60 family protein; The function of this domain is unknown. It is found in several lipoproteins; Family membership.
CDM67339.1 protein networkhttps://string-db.org/network/1216932.CM240_0165Hypothetical protein; Family membership.
CDM67340.1 protein networkhttps://string-db.org/network/1216932.CM240_0166Transcriptional regulator, AbrB family; This domain is found in AbrB from Bacillus subtilis. AbrB is an ambiactive repressor and activator of the transcription of genes expressed during the trans [...]
CDM67341.1 protein networkhttps://string-db.org/network/1216932.CM240_0167Two component transcriptional regulator, winged helix family; Two-component signal transduction systems enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, an [...]
CDM67342.1 protein networkhttps://string-db.org/network/1216932.CM240_0168Histidine kinase, Adenylyl cyclase,Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bact [...]
CDM67343.1 protein networkhttps://string-db.org/network/1216932.CM240_0169Putative Serine protease; This group of serine peptidases and non-peptidase homologues belong to the MEROPS peptidase family S1,subfamily S1C (protease Do subfamily, clan PS(S)). A type example i [...]
CDM67344.1 protein networkhttps://string-db.org/network/1216932.CM240_0170Putative secreted protein.
CDM67345.1 protein networkhttps://string-db.org/network/1216932.CM240_0171ABC-3 transport family; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily, which uses the hydrolysis of ATP to energise diverse biological systems. ABC transporters minimally [...]
CDM67346.1 protein networkhttps://string-db.org/network/1216932.CM240_0172ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters; High confidence in function and specificity.
CDM67347.1 protein networkhttps://string-db.org/network/1216932.CM240_0173Hypothetical protein.
CDM67348.1 protein networkhttps://string-db.org/network/1216932.CM240_0174This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virule [...]
CDM67349.1 protein networkhttps://string-db.org/network/1216932.CM240_0175Hypothetical protein.
CDM67350.1 protein networkhttps://string-db.org/network/1216932.CM240_0176Putative membrane protein.
CDM67351.1 protein networkhttps://string-db.org/network/1216932.CM240_0177Hypothetical protein; High confidence in function and specificity.
CDM67352.1 protein networkhttps://string-db.org/network/1216932.CM240_0178Hypothetical protein.
CDM67353.1 protein networkhttps://string-db.org/network/1216932.CM240_0179VanW family protein; Family members include vancomycin resistance protein W (VanW). Genes encoding members of this family have been found in vancomycin resistance gene clusters vanB and vanG; Hig [...]
CDM67354.1 protein networkhttps://string-db.org/network/1216932.CM240_0180Putative protein.
CDM67355.1 protein networkhttps://string-db.org/network/1216932.CM240_01812-nitropropane dioxygenase; Nitronate monooxygenase (NMO), formerly referred to as 2-nitropropane dioxygenase (NPD) (, is an FMN-dependent enzyme that uses molecular oxygen to oxidize (anionic) a [...]
CDM67356.1 protein networkhttps://string-db.org/network/1216932.CM240_0182Peptidil-prolyl cis-trans isomerase; Peptidylprolyl isomerase is an enzyme that accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopepti [...]
CDM67358.1 protein networkhttps://string-db.org/network/1216932.CM240_0185Hypothetical protein; Family membership.
CDM67359.1 protein networkhttps://string-db.org/network/1216932.CM240_0186Hypothetical protein; High confidence in function and specificity.
CDM67360.1 protein networkhttps://string-db.org/network/1216932.CM240_0189Hypothetical protein; Family membership.
CDM67361.1 protein networkhttps://string-db.org/network/1216932.CM240_0190Hypothetical protein.
yqjE protein networkhttps://string-db.org/network/1216932.CM240_0191Putative Peptidase T-like protein; This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification. Family M20 are Glutamate carboxypeptidases [...]
CDM67363.1 protein networkhttps://string-db.org/network/1216932.CM240_0192Hypothetical protein; Family membership.
CDM67364.1 protein networkhttps://string-db.org/network/1216932.CM240_0193Transcriptional regulator, AsnC family; The many bacterial transcription regulation proteins which bind DNA through a 'helix-turn-helix' motif can be classified into subfamilies on the basis of s [...]
CDM67365.1 protein networkhttps://string-db.org/network/1216932.CM240_0194Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes,such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the bas [...]
CDM67366.1 protein networkhttps://string-db.org/network/1216932.CM240_0195Transposase; High confidence in function and specificity.
CDM67367.1 protein networkhttps://string-db.org/network/1216932.CM240_0196Hypothetical protein; High confidence in function and specificity.
CDM67368.1 protein networkhttps://string-db.org/network/1216932.CM240_0197Peptidase family M50; pfam02163; High confidence in function and specificity.
CDM67369.1 protein networkhttps://string-db.org/network/1216932.CM240_0198Putative amidohydrolase; The carbon-nitrogen hydrolase domain is an around 265-residue domain found in numerous enzymes involved in the reduction of organic nitrogen compounds and ammonia product [...]
CDM67370.1 protein networkhttps://string-db.org/network/1216932.CM240_0200Rhodanese Homology Domain; Family membership.
CDM67371.1 protein networkhttps://string-db.org/network/1216932.CM240_0201Thioredoxin; Family membership; Belongs to the thioredoxin family.
CDM67372.1 protein networkhttps://string-db.org/network/1216932.CM240_0202Thioredoxin reductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger F [...]
CDM67373.1 protein networkhttps://string-db.org/network/1216932.CM240_0203Hypothetical protein; Family membership.
CDM67374.1 protein networkhttps://string-db.org/network/1216932.CM240_0204Hypothetical protein.
CDM67375.1 protein networkhttps://string-db.org/network/1216932.CM240_0205Putative transcriptional regulator; High confidence in function and specificity.
cas6 protein networkhttps://string-db.org/network/1216932.CM240_0206Crispr-associated protein Cas6; This group of families is one of several protein families that are always found associated with prokaryotic CRISPRs, themselves a family of clustered regularly int [...]
CDM67377.1 protein networkhttps://string-db.org/network/1216932.CM240_0207CRISPR-associated protein CXXC_CXXC region; CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these rep [...]
CDM67378.1 protein networkhttps://string-db.org/network/1216932.CM240_0208CRISPR-associated regulatory protein Cst2; This group of families is one of several protein families that are always found associated with prokaryotic CRISPRs, themselves a family of clustered re [...]
CDM67379.1 protein networkhttps://string-db.org/network/1216932.CM240_0209CRISPR-associated protein Cas5 family; CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats [...]
CDM67380.1 protein networkhttps://string-db.org/network/1216932.CM240_0210Cas3 appears to be a helicase, with regions found by PF00270 (DEAD/DEAH box helicase) and PF00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain reg [...]
CDM67381.1 protein networkhttps://string-db.org/network/1216932.CM240_0211CRISPR-associated Cas4 family protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (vir [...]
cas1 protein networkhttps://string-db.org/network/1216932.CM240_0212CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viru [...]
cas2 protein networkhttps://string-db.org/network/1216932.CM240_0213Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposab [...]
CDM67385.1 protein networkhttps://string-db.org/network/1216932.CM240_0215Hypothetical protein.
CDM67386.1 protein networkhttps://string-db.org/network/1216932.CM240_0216Hypothetical protein.
CDM67387.1 protein networkhttps://string-db.org/network/1216932.CM240_0217Hypothetical protein; Family membership.
CDM67388.1 protein networkhttps://string-db.org/network/1216932.CM240_0218Hypothetical protein; Family membership.
CDM67389.1 protein networkhttps://string-db.org/network/1216932.CM240_0219Putative membrane protein; High confidence in function and specificity.
CDM67390.1 protein networkhttps://string-db.org/network/1216932.CM240_0220Hypothetical protein; Family membership.
CDM67391.1 protein networkhttps://string-db.org/network/1216932.CM240_0221Hypothetical protein; High confidence in function and specificity.
CDM67392.1 protein networkhttps://string-db.org/network/1216932.CM240_0222DNA/RNA helicase, superfamily II, SNF2 family; Bacterial SNF2 helicase associated; pfam08455 and pfam00176; High confidence in function and specificity.
CDM67393.1 protein networkhttps://string-db.org/network/1216932.CM240_0223Hypothetical protein; Family membership.
CDM67394.1 protein networkhttps://string-db.org/network/1216932.CM240_0224Hypothetical protein; Family membership.
CDM67395.1 protein networkhttps://string-db.org/network/1216932.CM240_0225Hypothetical protein.
CDM67396.1 protein networkhttps://string-db.org/network/1216932.CM240_0226Hypothetical protein; Family membership.
CDM67397.1 protein networkhttps://string-db.org/network/1216932.CM240_0227Hypothetical protein; Family membership.
CDM67398.1 protein networkhttps://string-db.org/network/1216932.CM240_0228Hypothetical protein; High confidence in function and specificity.
CDM67399.1 protein networkhttps://string-db.org/network/1216932.CM240_0229Putative membrane protein.
CDM67400.1 protein networkhttps://string-db.org/network/1216932.CM240_0230Putative membrane protein.
CDM67401.1 protein networkhttps://string-db.org/network/1216932.CM240_0231Hypothetical protein; Family membership.
CDM67402.1 protein networkhttps://string-db.org/network/1216932.CM240_02326-Pyruvoyl tetrahydrobiopterin synthase catalyses the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin, the second of three enzymatic steps in the synthesis of tetrahydr [...]
queE protein networkhttps://string-db.org/network/1216932.CM240_02337-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to [...]
folE protein networkhttps://string-db.org/network/1216932.CM240_0234GTP cyclohydrolase I catalyses the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP. This reaction is the first step in the biosynthesis of tetrahydrofolate in prokaryotes.T [...]
queC protein networkhttps://string-db.org/network/1216932.CM240_02357-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
queF protein networkhttps://string-db.org/network/1216932.CM240_0236NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydro [...]
CDM67407.1 protein networkhttps://string-db.org/network/1216932.CM240_0237Peptidase family M28; pfam04389; Family membership.
CDM67408.1 protein networkhttps://string-db.org/network/1216932.CM240_0238Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond. Some members with only the active site are not separated from [...]
CDM67409.1 protein networkhttps://string-db.org/network/1216932.CM240_0239Hypothetical protein.
CDM67410.1 protein networkhttps://string-db.org/network/1216932.CM240_0240Hypothetical protein; High confidence in function and specificity.
CDM67411.1 protein networkhttps://string-db.org/network/1216932.CM240_0241Putative transcriptional regulator; Bacterial regulatory helix-turn-helix proteins, AraC family; pfam00165; Family membership.
CDM67412.1 protein networkhttps://string-db.org/network/1216932.CM240_0242Hypothetical protein; Frameshift; Family membership.
CDM67413.1 protein networkhttps://string-db.org/network/1216932.CM240_0243Putative iron transporter; High confidence in function and specificity.
CDM67414.1 protein networkhttps://string-db.org/network/1216932.CM240_0244ATP binding cassette (ABC) transporters are a ubiquitous family of importer and exporter proteins that consist of two alpha-helical transmembrane (TM) domains,which form a translocation pathway, [...]
CDM67415.1 protein networkhttps://string-db.org/network/1216932.CM240_0245Iron ABC transporter permease; This is a subfamily of bacterial binding-protein-dependent transport systems family, and includes transport system permease proteins involved in the transport acros [...]
CDM67416.1 protein networkhttps://string-db.org/network/1216932.CM240_0246Putative iron chelate uptake ABC transporter,ATP-binding protein; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membran [...]
CDM67418.1 protein networkhttps://string-db.org/network/1216932.CM240_0248Putative secreted protein.
CDM67419.1 protein networkhttps://string-db.org/network/1216932.CM240_0249Putative membrane protein; Family membership.
CDM67420.1 protein networkhttps://string-db.org/network/1216932.CM240_0250ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDM67421.1 protein networkhttps://string-db.org/network/1216932.CM240_0251ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDM67422.1 protein networkhttps://string-db.org/network/1216932.CM240_0252Hypothetical protein.
CDM67423.1 protein networkhttps://string-db.org/network/1216932.CM240_0253Putative membrane protein.
CDM67424.1 protein networkhttps://string-db.org/network/1216932.CM240_0254Hypothetical protein; Family membership.
ftsH1 protein networkhttps://string-db.org/network/1216932.CM240_0255ATP-dependent zinc metalloprotease FtsH 1; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral me [...]
CDM67426.1 protein networkhttps://string-db.org/network/1216932.CM240_0256Hypothetical protein; Family membership.
CDM67427.1 protein networkhttps://string-db.org/network/1216932.CM240_0257HAD hydrolase; The Haloacid Dehydrogenase (HAD) superfamily includes phosphatases, phosphonatases, P-type ATPases,beta-phosphoglucomutases, phosphomannomutases, and dehalogenases, which are invol [...]
CDM67428.1 protein networkhttps://string-db.org/network/1216932.CM240_0258Hypothetical protein; Family membership.
vgaB protein networkhttps://string-db.org/network/1216932.CM240_0259ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
speE protein networkhttps://string-db.org/network/1216932.CM240_0260Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermid [...]
speH protein networkhttps://string-db.org/network/1216932.CM240_0261S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of th [...]
CDM67432.1 protein networkhttps://string-db.org/network/1216932.CM240_0262Amino acid permeases are membrane permeases involved in the transport of amino acids into the cell. A number of such proteins have been found to be evolutionary related; High confidence in functi [...]
CDM67433.1 protein networkhttps://string-db.org/network/1216932.CM240_0263Methyl-accepting chemotaxis protein; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs; High confidence in function and specificity.
aspS1 protein networkhttps://string-db.org/network/1216932.CM240_0264Aspartate-tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end [...]
gatC protein networkhttps://string-db.org/network/1216932.CM240_0265Aspartyl/glutamyl-tRNA(Asn/Gln)amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) [...]
gatA2 protein networkhttps://string-db.org/network/1216932.CM240_0266Glutamyl-tRNA(Gln) amidotransferase subunit A 2; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl [...]
gatB protein networkhttps://string-db.org/network/1216932.CM240_0267Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu [...]
CDM67438.1 protein networkhttps://string-db.org/network/1216932.CM240_0268Hypothetical protein.
CDM67439.1 protein networkhttps://string-db.org/network/1216932.CM240_0269Hypothetical protein.
rbr3A1 protein networkhttps://string-db.org/network/1216932.CM240_0270Reverse rubrerythrin-1; Functions as the terminal component of an NADH peroxidase (NADH:H2O2 oxidoreductase) when using NADH:rubredoxin oxidoreductase (NROR) and rubredoxin (Rd) as electron trans [...]
rbr3A3 protein networkhttps://string-db.org/network/1216932.CM240_0271Reverse rubrerythrin-1; Rubrerythrin (Rr), found in anaerobic sulphate-reducing bacteria, is a fusion protein containing an N-terminal diiron-binding domain and a C-terminal domain homologous to [...]
CDM67442.1 protein networkhttps://string-db.org/network/1216932.CM240_0272Putative membrane protein.
asd protein networkhttps://string-db.org/network/1216932.CM240_0273The semialdehyde dehydrogenase family is found in N-acetyl-glutamine semialdehyde dehydrogenase (AgrC),which is involved in arginine biosynthesis, and aspartate-semialdehyde dehydrogenase,an enzy [...]
CDM67444.1 protein networkhttps://string-db.org/network/1216932.CM240_0274Putative membrane protein.
CDM67445.1 protein networkhttps://string-db.org/network/1216932.CM240_0278Hypothetical protein; Family membership.
CDM67446.1 protein networkhttps://string-db.org/network/1216932.CM240_0279Hypothetical protein; Family membership.
CDM67447.1 protein networkhttps://string-db.org/network/1216932.CM240_0280Hypothetical protein; Family membership.
CDM67448.1 protein networkhttps://string-db.org/network/1216932.CM240_0281Hypothetical protein; High confidence in function and specificity.
CDM67449.1 protein networkhttps://string-db.org/network/1216932.CM240_0282Two component transcriptional regulator, winged helix family protein; High confidence in function and specificity.
bcrA protein networkhttps://string-db.org/network/1216932.CM240_0283Bacitracin transport ATP-binding protein BcrA; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporter [...]
CDM67451.1 protein networkhttps://string-db.org/network/1216932.CM240_0284Hypothetical protein; High confidence in function and specificity.
CDM67452.1 protein networkhttps://string-db.org/network/1216932.CM240_0285Histidine kinase; Two-component signal transduction systems enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions, Some bacteria can conta [...]
CDM67453.1 protein networkhttps://string-db.org/network/1216932.CM240_0286CBS domain-containing protein; CBS domains are small intracellular modules that pair together to form a stable globular domain. This family represents a single CBS domain. Pairs of these domains [...]
CDM67454.1 protein networkhttps://string-db.org/network/1216932.CM240_0287HAD-superfamily hydrolase; The Haloacid Dehydrogenase (HAD) superfamily includes phosphatases, phosphonatases, P-type ATPases,beta-phosphoglucomutases, phosphomannomutases, and dehalogenases, whi [...]
CDM67455.1 protein networkhttps://string-db.org/network/1216932.CM240_0288Transposase; High confidence in function and specificity.
CDM67456.1 protein networkhttps://string-db.org/network/1216932.CM240_0289Transposase; The helix-turn-helix (HTH) is a major structural motif capable of binding DNA. It is composed of two alpha helices joined by a short strand of amino acids and is found in many protei [...]
CDM67457.1 protein networkhttps://string-db.org/network/1216932.CM240_0290Arsenical pump membrane protein; This domain is found in proteins belonging to the CitM transporter and Na+/sulphate symporter families; High confidence in function and specificity.
CDM67458.1 protein networkhttps://string-db.org/network/1216932.CM240_0291This family of proteins are found in a range of bacteria. The conserved region contains a conserved histidine and cysteine, suggesting that these proteins have an enzymatic activity. Several memb [...]
fruA protein networkhttps://string-db.org/network/1216932.CM240_0293PTS system fructose-specific EIIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphor [...]
fruK protein networkhttps://string-db.org/network/1216932.CM240_02941-phosphofructokinase; This domain is found in a variety of carbohydrate and pyrimidine kinases. It is found in phosphomethylpyrimidine kinase, which is part of the thiamine pyrophosphate (TPP) s [...]
fruR protein networkhttps://string-db.org/network/1216932.CM240_0295Putative HTH-type transcriptional regulator FruR; The deoR-type HTH domain is a DNA-binding,helix-turn-helix (HTH) domain of about 50-60 amino acids present in transcription regulators of the deo [...]
CDM67463.1 protein networkhttps://string-db.org/network/1216932.CM240_0296Hypothetical protein.
CDM67464.1 protein networkhttps://string-db.org/network/1216932.CM240_0297Iron (Metal) dependent repressor, DtxR family; The dtxR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 65 residues present in metalloregulators of the dtxR/mntR [...]
CDM67465.1 protein networkhttps://string-db.org/network/1216932.CM240_0298Hypothetical protein; Family membership.
CDM67466.1 protein networkhttps://string-db.org/network/1216932.CM240_0299Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) [...]
CDM67467.1 protein networkhttps://string-db.org/network/1216932.CM240_0300Iron transporter FeoB; Escherichia coli has an iron(II) transport system (feo) which may make an important contribution to the iron supply of the cell under anaerobic conditions [1]. FeoB has bee [...]
CDM67468.1 protein networkhttps://string-db.org/network/1216932.CM240_0301Cystathionine gamma-lyase; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase,Cystathi [...]
CDM67469.1 protein networkhttps://string-db.org/network/1216932.CM240_0302Radical SAM proteins catalyse diverse reactions,including unusual methylations,isomerisation,sulphur insertion, ring formation, anaerobic oxidation and protein radical formation; High confidence [...]
CDM67470.1 protein networkhttps://string-db.org/network/1216932.CM240_0303O-acetylhomoserine (thiol)-lyase; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase,C [...]
nifD1 protein networkhttps://string-db.org/network/1216932.CM240_0304Nitrogenase; Enzymes belonging to this family include cofactor-requiring nitrogenases and protochlorophyllide reductase. The key enzymatic reactions in nitrogen fixation are catalysed by the nitr [...]
nifK1 protein networkhttps://string-db.org/network/1216932.CM240_0305Nitrogenase; Enzymes belonging to this family include cofactor-requiring nitrogenases and protochlorophyllide reductase. The key enzymatic reactions in nitrogen fixation are catalysed by the nitr [...]
CDM67473.1 protein networkhttps://string-db.org/network/1216932.CM240_0306NLPA lipoprotein; This family of bacterial lipoproteins contains several antigenic members, that may be involved in bacterial virulence. Their precise function is unknown. However they are probab [...]
metN1 protein networkhttps://string-db.org/network/1216932.CM240_0307Methionine import ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC t [...]
CDM67475.1 protein networkhttps://string-db.org/network/1216932.CM240_0308ABC transporter permease; Bacterial binding protein-dependent transport systems multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two reciprocally homol [...]
CDM67476.1 protein networkhttps://string-db.org/network/1216932.CM240_0309NifB-domain protein; This family contains several NIF (B, Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen t [...]
CDM67477.1 protein networkhttps://string-db.org/network/1216932.CM240_0310Hypothetical protein.
CDM67478.1 protein networkhttps://string-db.org/network/1216932.CM240_0311Oxidoreductase/nitrogenase component 1; Enzymes belonging to this family include cofactor-requiring nitrogenases and protochlorophyllide reductase. The key enzymatic reactions in nitrogen fixatio [...]
CDM67479.1 protein networkhttps://string-db.org/network/1216932.CM240_0312Oxidoreductase/nitrogenase component 1; Enzymes belonging to this family include cofactor-requiring nitrogenases and protochlorophyllide reductase. The key enzymatic reactions in nitrogen fixatio [...]
nifH4 protein networkhttps://string-db.org/network/1216932.CM240_0313Nitrogenase iron protein 4; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Be [...]
CDM67481.1 protein networkhttps://string-db.org/network/1216932.CM240_0314A N-acetylmuramoyl-L-alanine amidase is an enzyme that catalyzes a chemical reaction that cleaves the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycope [...]
CDM67482.1 protein networkhttps://string-db.org/network/1216932.CM240_0315Hypothetical protein; Family membership.
CDM67483.1 protein networkhttps://string-db.org/network/1216932.CM240_0316ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters; Family membership.
CDM67484.1 protein networkhttps://string-db.org/network/1216932.CM240_0317Hypothetical protein; Family membership.
CDM67485.1 protein networkhttps://string-db.org/network/1216932.CM240_0318Hypothetical protein; Family membership.
CDM67486.1 protein networkhttps://string-db.org/network/1216932.CM240_0319MoxR-like ATPases; Family membership.
CDM67487.1 protein networkhttps://string-db.org/network/1216932.CM240_0320Hypothetical protein; High confidence in function and specificity.
CDM67488.1 protein networkhttps://string-db.org/network/1216932.CM240_0321Putative membrane protein.
CDM67489.1 protein networkhttps://string-db.org/network/1216932.CM240_0322Hypothetical protein; Family membership.
vanR1 protein networkhttps://string-db.org/network/1216932.CM240_0323DNA-binding response regulator; Some bacteria can contain up to as many as 200 two-component systems that need tight regulation to prevent unwanted cross-talk.These pathways have been adapted to [...]
CDM67491.1 protein networkhttps://string-db.org/network/1216932.CM240_0324Histidine kinases usually have an N-terminal ligand-binding domain and a C-terminal kinase domain, but other domains may also be present. The kinase domain is responsible for the autophosphorylat [...]
pdxT protein networkhttps://string-db.org/network/1216932.CM240_0325Glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to th [...]
pdxS protein networkhttps://string-db.org/network/1216932.CM240_0326Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the Pd [...]
CDM67494.1 protein networkhttps://string-db.org/network/1216932.CM240_0327Hypothetical protein; High confidence in function and specificity.
cypC protein networkhttps://string-db.org/network/1216932.CM240_0328Fatty-acid peroxygenase; Cytochrome P450 enzymes are a superfamily of haem-containing mono-oxygenases that are found in all kingdoms of life, and which show extraordinary diversity in their react [...]
dexB protein networkhttps://string-db.org/network/1216932.CM240_0329Glucan 1,6-alpha-glucosidase; Alpha amylase is classified as family 13 of the glycosyl hydrolases. The structure is an 8 stranded alpha/beta barrel containing the active site, interrupted by a 70 [...]
CDM67497.1 protein networkhttps://string-db.org/network/1216932.CM240_0330Hypothetical protein; Family membership.
ywdH protein networkhttps://string-db.org/network/1216932.CM240_0331Aldehyde dehydrogenases are enzymes that oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor; High confidence in function and specificity.
CDM67499.1 protein networkhttps://string-db.org/network/1216932.CM240_0332Putative protein.
CDM67500.1 protein networkhttps://string-db.org/network/1216932.CM240_0333Putative uncharacterized protein; Family membership.
CDM67501.1 protein networkhttps://string-db.org/network/1216932.CM240_0334Sortase family protein; Sortase D (SrtD) is a membrane transpeptidase found,in gram-positive bacteria that anchors surface proteins to,peptidoglycans of the bacterial cell wall envelope. This,inv [...]
CDM67502.1 protein networkhttps://string-db.org/network/1216932.CM240_0335Putative uncharacterized protein; Family membership.
CDM67503.1 protein networkhttps://string-db.org/network/1216932.CM240_0336Putative membrane protein.
CDM67504.1 protein networkhttps://string-db.org/network/1216932.CM240_0337Involved in spore core dehydration; might be involved in the transport of something into or out of the forespore or could be required for some modification of the cortex peptidoglycan structure; [...]
CDM67505.1 protein networkhttps://string-db.org/network/1216932.CM240_0338Hypothetical protein.
CDM67506.1 protein networkhttps://string-db.org/network/1216932.CM240_0339Acetyltransferase, GNAT family; Acetyltransferase (or transacetylase) is a type of transferase enzyme that transfers an acetyl group; Family membership.
CDM67507.1 protein networkhttps://string-db.org/network/1216932.CM240_0340Hypothetical protein; Family membership.
CDM67508.1 protein networkhttps://string-db.org/network/1216932.CM240_0341Hypothetical protein; Family membership.
metG protein networkhttps://string-db.org/network/1216932.CM240_0342Methionine-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
CDM67510.1 protein networkhttps://string-db.org/network/1216932.CM240_0343Putative membrane protein.
CDM67511.1 protein networkhttps://string-db.org/network/1216932.CM240_0344Hypothetical protein; Family membership.
CDM67512.1 protein networkhttps://string-db.org/network/1216932.CM240_0345TatD family hydrolase; His family of proteins are related to a large superfamily of metalloenzyme. TatD, a member of this family has been shown experimentally to be a DNase enzyme; High confidenc [...]
CDM67513.1 protein networkhttps://string-db.org/network/1216932.CM240_0346Hypothetical protein; High confidence in function and specificity.
rnmV protein networkhttps://string-db.org/network/1216932.CM240_0347Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
rsmA protein networkhttps://string-db.org/network/1216932.CM240_0348Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S part [...]
CDM67516.1 protein networkhttps://string-db.org/network/1216932.CM240_0349Hypothetical protein.
lgt1 protein networkhttps://string-db.org/network/1216932.CM240_0350Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
CDM67518.1 protein networkhttps://string-db.org/network/1216932.CM240_0351Putative protein.
mrp protein networkhttps://string-db.org/network/1216932.CM240_0352MinD family ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
CDM67520.1 protein networkhttps://string-db.org/network/1216932.CM240_0353Members of this family are transcriptional regulators that appear to be related to the PF01047 family. This family includes PadR Q9EXE6 a protein that is involved in negative regulation of phenol [...]
CDM67521.1 protein networkhttps://string-db.org/network/1216932.CM240_0354DegV domain-containing protein CA_C1624; The structure of this protein revealed a bound fatty-acid molecule in a pocket between the two protein domains. The structure indicates that this family h [...]
CDM67522.1 protein networkhttps://string-db.org/network/1216932.CM240_0355Transcriptional regulator; High confidence in function and specificity.
rplY protein networkhttps://string-db.org/network/1216932.CM240_035650S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
CDM67524.1 protein networkhttps://string-db.org/network/1216932.CM240_0357Dhha1 domain protein; This domain is often found adjacent to the DHH domain PF01368 and is called DHHA1 for DHH associated domain. This domain is diagnostic of DHH subfamily 1 members. This domai [...]
CDM67525.1 protein networkhttps://string-db.org/network/1216932.CM240_0358Putative nitric oxide reductase flavoprotein; High confidence in function and specificity.
truA1 protein networkhttps://string-db.org/network/1216932.CM240_0359tRNA pseudouridine synthase A 1; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
CDM67527.1 protein networkhttps://string-db.org/network/1216932.CM240_0360Putative membrane protein.
CDM67528.1 protein networkhttps://string-db.org/network/1216932.CM240_0361Hypothetical protein.
CDM67529.1 protein networkhttps://string-db.org/network/1216932.CM240_0362Hypothetical protein; Family membership.
CDM67530.1 protein networkhttps://string-db.org/network/1216932.CM240_0363HD domains are metal dependent phosphohydrolases; High confidence in function and specificity.
rlmH protein networkhttps://string-db.org/network/1216932.CM240_0364Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
CDM67532.1 protein networkhttps://string-db.org/network/1216932.CM240_0365Transcriptional regulator.
CDM67533.1 protein networkhttps://string-db.org/network/1216932.CM240_0366The Nudix family is a protein family of phosphohydrolases.[1][2][3] Using water-mediated catalysis they break a phosphate bond in their substrate to create two products; High confidence in functi [...]
CDM67534.1 protein networkhttps://string-db.org/network/1216932.CM240_0367Sensor histidine kinase/response regulator; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine [...]
CDM67535.1 protein networkhttps://string-db.org/network/1216932.CM240_0368Hypothetical protein; Family membership.
CDM67536.1 protein networkhttps://string-db.org/network/1216932.CM240_0369IS66 Orf2 like protein; This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition; Family member [...]
CDM67537.1 protein networkhttps://string-db.org/network/1216932.CM240_0370Transposase and inactivated derivatives [DNA,replication, recombination, and repair]; High confidence in function and specificity.
CDM67538.1 protein networkhttps://string-db.org/network/1216932.CM240_0371Hypothetical protein; Family membership.
CDM67539.1 protein networkhttps://string-db.org/network/1216932.CM240_0372Hypothetical protein; Family membership.
aroA3 protein networkhttps://string-db.org/network/1216932.CM240_0373This entry represents the core domain of 3-phosphoshikimate 1-carboxyvinyltransferase and UDP-N-acetylglucosamine 1-carboxyvinyltransferase. It transfers enolpryruvate from phosphoenolpyruvate to [...]
CDM67541.1 protein networkhttps://string-db.org/network/1216932.CM240_0374Hypothetical protein.
CDM67542.1 protein networkhttps://string-db.org/network/1216932.CM240_0375Hypothetical protein; Family membership.
CDM67543.1 protein networkhttps://string-db.org/network/1216932.CM240_0376Hypothetical protein; Family membership.
CDM67544.1 protein networkhttps://string-db.org/network/1216932.CM240_0377Hypothetical protein; Family membership.
CDM67545.1 protein networkhttps://string-db.org/network/1216932.CM240_0378Hypothetical protein; Family membership.
CDM67546.1 protein networkhttps://string-db.org/network/1216932.CM240_0379Putative membrane protein.
CDM67547.1 protein networkhttps://string-db.org/network/1216932.CM240_0380Putative membrane protein.
CDM67548.1 protein networkhttps://string-db.org/network/1216932.CM240_0381Histidine kinase, Adenylyl cyclase,Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bact [...]
CDM67549.1 protein networkhttps://string-db.org/network/1216932.CM240_0382Response regulators consisting of a CheY-like,receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; High confidence in function and specificity.
CDM67550.1 protein networkhttps://string-db.org/network/1216932.CM240_0383Hypothetical protein; Family membership.
CDM67551.1 protein networkhttps://string-db.org/network/1216932.CM240_0384Putative membrane protein.
CDM67552.1 protein networkhttps://string-db.org/network/1216932.CM240_0385Hypothetical protein; Family membership.
CDM67553.1 protein networkhttps://string-db.org/network/1216932.CM240_0386Hypothetical protein.
CDM67554.1 protein networkhttps://string-db.org/network/1216932.CM240_0387Hypothetical protein.
CDM67555.1 protein networkhttps://string-db.org/network/1216932.CM240_0388Transcriptional regulator, HxlR family; The hxlR-type HTH domain is a domain of 90-100 amino acids present in putative transcription regulators with a winged helix-turn-helix (wHTH) structure. Th [...]
azoR2 protein networkhttps://string-db.org/network/1216932.CM240_0389FMN-dependent NADH-azoreductase 2; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its a [...]
CDM67557.1 protein networkhttps://string-db.org/network/1216932.CM240_0390MDR-type permease; Among the different families of transporter, only two occur ubiquitously in all classifications of organisms. These are the ATP-Binding Cassette (ABC) superfamily and the Major [...]
CDM67558.1 protein networkhttps://string-db.org/network/1216932.CM240_0391MarR-family transcriptional regulator; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a r [...]
CDM67559.1 protein networkhttps://string-db.org/network/1216932.CM240_0392MFS transporter; Among the different families of transporter, only two occur ubiquitously in all classifications of organisms. These are the ATP-Binding Cassette (ABC) superfamily and the Major F [...]
CDM67560.1 protein networkhttps://string-db.org/network/1216932.CM240_0393Putative transcription regulator; High confidence in function and specificity.
CDM67561.1 protein networkhttps://string-db.org/network/1216932.CM240_0394NlpA lipoprotein; High confidence in function and specificity.
CDM67562.1 protein networkhttps://string-db.org/network/1216932.CM240_0395Binding-protein-dependent transport system inner membrane protein; This region seems [PMID: 1738314] to be located in a cytoplasmic loop between two transmembrane domains. Apart from the conserve [...]
CDM67563.1 protein networkhttps://string-db.org/network/1216932.CM240_0396ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDM67564.1 protein networkhttps://string-db.org/network/1216932.CM240_0397Cobalamin (vitamin B12) biosynthesis CbiM protein; This entry represents the integral membrane protein CbiM, which forms part of the energy-coupling factor (ECF) transporter complex CbiMNOQ that [...]
CDM67565.1 protein networkhttps://string-db.org/network/1216932.CM240_0398Cobalt ABC transporter permease CbiQ; This protein represents the transmembrane component from a number of ABC and ECF transporters; Hypothetical protein.
CDM67566.1 protein networkhttps://string-db.org/network/1216932.CM240_0399ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDM67567.1 protein networkhttps://string-db.org/network/1216932.CM240_0400Carbon-monoxide dehydrogenase, catalytic subunit; This family includes both hybrid-cluster proteins and the beta chain of carbon monoxide dehydrogenase. The hybrid-cluster proteins contain two Fe [...]
CDM67568.1 protein networkhttps://string-db.org/network/1216932.CM240_0401ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDM67569.1 protein networkhttps://string-db.org/network/1216932.CM240_0402Hypothetical protein; High confidence in function and specificity.
CDM67570.1 protein networkhttps://string-db.org/network/1216932.CM240_0403Transcriptional regulator; This entry represents a domain that is almost always found associated with the response regulator receiver domain (see IPR001789). It may play a role in DNA binding [PM [...]
CDM67571.1 protein networkhttps://string-db.org/network/1216932.CM240_0404Hypothetical protein; High confidence in function and specificity.
CDM67572.1 protein networkhttps://string-db.org/network/1216932.CM240_0405Hypothetical protein; Family membership.
CDM67573.1 protein networkhttps://string-db.org/network/1216932.CM240_0406MATE efflux family protein; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range of cati [...]
CDM67574.1 protein networkhttps://string-db.org/network/1216932.CM240_0407Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; This family contains hydrolases that break carbon-nitrogen bonds. The family includes: NitrilaseAliphatic amidaseBiotidinaseP4325 [...]
CDM67575.1 protein networkhttps://string-db.org/network/1216932.CM240_0408The PhnA protein family includes the uncharacterised Escherichia coli protein PhnA and its homologues. The E. coli phnA gene is part of a large operon associated with alkylphosphonate uptake and [...]
CDM67576.1 protein networkhttps://string-db.org/network/1216932.CM240_0409Hypothetical protein.
CDM67577.1 protein networkhttps://string-db.org/network/1216932.CM240_0410Hypothetical protein; Family membership.
CDM67578.1 protein networkhttps://string-db.org/network/1216932.CM240_0411Hypothetical protein; High confidence in function and specificity.
malP protein networkhttps://string-db.org/network/1216932.CM240_0412Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural s [...]
CDM67580.1 protein networkhttps://string-db.org/network/1216932.CM240_0413TrkA C-terminal domain protein; This domain is often found next to the PF02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. [...]
cpx protein networkhttps://string-db.org/network/1216932.CM240_0414Putative permease; These proteins generally contain 12 transmembrane regions. Many members of this family are uncharacterised and may transport other substrates; High confidence in function and s [...]
xpt protein networkhttps://string-db.org/network/1216932.CM240_0415Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
rbr protein networkhttps://string-db.org/network/1216932.CM240_0416Rubrerythrin; May provide oxidative stress protection via catalytic reduction of intracellular hydrogen peroxide; High confidence in function and specificity.
sodA protein networkhttps://string-db.org/network/1216932.CM240_0417Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
CDM67585.1 protein networkhttps://string-db.org/network/1216932.CM240_0418ExsB family protein; IPR011063 -This entry represents the PP-loop motif superfamily; High confidence in function and specificity; Belongs to the TtcA family.
CDM67586.1 protein networkhttps://string-db.org/network/1216932.CM240_0419Glyoxalase; IPR025870. Glyoxalase-like_dom; High confidence in function and specificity.
CDM67587.1 protein networkhttps://string-db.org/network/1216932.CM240_0420Alpha amylase is classified as family 13 of the glycosyl hydrolases. The structure is an 8 stranded alpha/beta barrel containing the active site, interrupted by a 70 a.a. calcium-binding domain p [...]
CDM67588.1 protein networkhttps://string-db.org/network/1216932.CM240_0421Citrate synthase (CS) catalyzes the condensation of,acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form,citrate and coenzyme A (CoA), the first step in the,oxidative citric acid cycle (TCA or [...]
CDM67589.1 protein networkhttps://string-db.org/network/1216932.CM240_0422Potassium channel subunit; IPR013099 This entry includes the two membrane helix type ion channels found in bacteria; High confidence in function and specificity.
ddl1 protein networkhttps://string-db.org/network/1216932.CM240_0423D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
CDM67591.1 protein networkhttps://string-db.org/network/1216932.CM240_0424DeoR family transcriptional regulator; High confidence in function and specificity.
CDM67592.1 protein networkhttps://string-db.org/network/1216932.CM240_0425Pyridoxine kinase; This protein is required for the synthesis of pyridoxal-5-phosphate from vitamin B6, and catalyses the conversion of pyridoxal to pyridoxal 5'-phosphate in the presence of ATP. [...]
CDM67593.1 protein networkhttps://string-db.org/network/1216932.CM240_0426Radical SAM proteins catalyse diverse reactions,including unusual methylations,isomerisation,sulphur insertion, ring formation, anaerobic oxidation and protein radical formation; High confidence [...]
gpmA protein networkhttps://string-db.org/network/1216932.CM240_04272,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
CDM67595.1 protein networkhttps://string-db.org/network/1216932.CM240_0428Putative membrane protein.
CDM67596.1 protein networkhttps://string-db.org/network/1216932.CM240_0429Hypothetical protein; Family membership.
CDM67597.1 protein networkhttps://string-db.org/network/1216932.CM240_0430Putative secreted protein.
uppP1 protein networkhttps://string-db.org/network/1216932.CM240_0431Undecaprenyl-diphosphatase 1; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
CDM67599.1 protein networkhttps://string-db.org/network/1216932.CM240_0432PAP2 family protein; PAP2 enzymes catalyse the dephosphorylation of phosphatidate, yielding diacylglycerol and inorganic phosphate; High confidence in function and specificity.
CDM67600.1 protein networkhttps://string-db.org/network/1216932.CM240_0433DNA polymerase beta domain-containing protein; Nucleotidyltransferase domain; pfam01909; High confidence in function and specificity.
CDM67601.1 protein networkhttps://string-db.org/network/1216932.CM240_0434Multicopper oxidases oxidise their substrate by accepting electrons at a mononuclear copper centre and transferring them to a trinuclear copper centre; dioxygen binds to the trinuclear centre and [...]
CDM67602.1 protein networkhttps://string-db.org/network/1216932.CM240_0435Hypothetical protein; High confidence in function and specificity; Belongs to the UPF0246 family.
CDM67603.1 protein networkhttps://string-db.org/network/1216932.CM240_0436Triacylglycerol lipase; Predicted acetyltransferases and hydrolases wit the alpha/beta hydrolase fold [General function prediction only; High confidence in function and specificity.
CDM67604.1 protein networkhttps://string-db.org/network/1216932.CM240_0437Hypothetical protein.
CDM67605.1 protein networkhttps://string-db.org/network/1216932.CM240_0438ArsC family protein; Several bacterial taxon have a chromosomal resistance system, encoded by the ars operon, for the detoxification of arsenate, arsenite, and antimonite; Family membership; Belo [...]
thiE protein networkhttps://string-db.org/network/1216932.CM240_0439Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monopho [...]
CDM67607.1 protein networkhttps://string-db.org/network/1216932.CM240_0440Predicted hydrolase (HAD superfamily) [General,function prediction only; High confidence in function and specificity.
CDM67608.1 protein networkhttps://string-db.org/network/1216932.CM240_0441Putative membrane protein.
CDM67609.1 protein networkhttps://string-db.org/network/1216932.CM240_0442Hypothetical protein; Family membership.
CDM67610.1 protein networkhttps://string-db.org/network/1216932.CM240_0443ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters; High confidence in function and specificity.
CDM67611.1 protein networkhttps://string-db.org/network/1216932.CM240_0444Putative ABC transporter; The domain this protein is found in predicted permeases and hypothetical transmembrane proteins; High confidence in function and specificity.
CDM67612.1 protein networkhttps://string-db.org/network/1216932.CM240_0445Galactose-1-phosphate uridylyltransferase is involved in the metabolism of galactose via the Leloir pathway.GalT catalyses the transfer of a uridine 5 -phosphoryl group from UDP-galactose 1-phosp [...]
CDM67613.1 protein networkhttps://string-db.org/network/1216932.CM240_0448Hypothetical protein; High confidence in function and specificity.
CDM67614.1 protein networkhttps://string-db.org/network/1216932.CM240_0449Hypothetical protein; High confidence in function and specificity.
CDM67615.1 protein networkhttps://string-db.org/network/1216932.CM240_0450Hypothetical protein; High confidence in function and specificity.
vanRB protein networkhttps://string-db.org/network/1216932.CM240_0451Regulatory protein VanRB; High confidence in function and specificity.
CDM67617.1 protein networkhttps://string-db.org/network/1216932.CM240_0452Sensor histidine kinase; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine protein kinase (HK) [...]
CDM67618.1 protein networkhttps://string-db.org/network/1216932.CM240_0453Putative membrane protein.
CDM67619.1 protein networkhttps://string-db.org/network/1216932.CM240_0454Macrolide export ATP-binding/permease protein,macB; High confidence in function and specificity.
yclH protein networkhttps://string-db.org/network/1216932.CM240_0455Putative ABC transporter ATP-binding protein; High confidence in function and specificity.
CDM67621.1 protein networkhttps://string-db.org/network/1216932.CM240_0456Hypothetical protein; High confidence in function and specificity.
CDM67622.1 protein networkhttps://string-db.org/network/1216932.CM240_0457Hypothetical protein; High confidence in function and specificity.
CDM67623.1 protein networkhttps://string-db.org/network/1216932.CM240_0458DNA mismatch repair protein MutS domain-containing protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacter [...]
CDM67624.1 protein networkhttps://string-db.org/network/1216932.CM240_0459Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS [...]
CDM67625.1 protein networkhttps://string-db.org/network/1216932.CM240_0460Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS [...]
CDM67626.1 protein networkhttps://string-db.org/network/1216932.CM240_0461Methyl-accepting chemotaxis proteins (MCPs) are a family of bacterial receptors that mediate chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellent [...]
CDM67627.1 protein networkhttps://string-db.org/network/1216932.CM240_0462Putative methyl-accepting chemotaxis protein; Bacterial chemotactic-signal transducers are proteins that respond to changes in the concentration of attractants and repellents in the environment, [...]
cax protein networkhttps://string-db.org/network/1216932.CM240_0463This is a family of sodium/calcium exchanger integral membrane proteins. This family covers the integral membrane regions of the proteins; High confidence in function and specificity.
CDM67629.1 protein networkhttps://string-db.org/network/1216932.CM240_0464Hypothetical protein; Family membership.
CDM67630.1 protein networkhttps://string-db.org/network/1216932.CM240_0465Putative undecaprenyl diphosphate synthetase; Previously known as uncharacterized protein family UPF0015, a single member of this family O82827 has been identified as an undecaprenyl diphosphate [...]
CDM67631.1 protein networkhttps://string-db.org/network/1216932.CM240_0466This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase. It [...]
CDM67632.1 protein networkhttps://string-db.org/network/1216932.CM240_0467Hypothetical protein.
CDM67633.1 protein networkhttps://string-db.org/network/1216932.CM240_0468Hypothetical protein.
CDM67634.1 protein networkhttps://string-db.org/network/1216932.CM240_0469Multi antimicrobial extrusion protein (MATE) also known as multidrug and toxin extrusion or multidrug and toxic compound extrusion is a family of proteins which function as drug/sodium or proton [...]
pepT protein networkhttps://string-db.org/network/1216932.CM240_0470Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
CDM67636.1 protein networkhttps://string-db.org/network/1216932.CM240_0471Hypothetical protein.
CDM67637.1 protein networkhttps://string-db.org/network/1216932.CM240_0472Peptidase S15; High confidence in function and specificity.
CDM67638.1 protein networkhttps://string-db.org/network/1216932.CM240_0473It has been found in bacterial sensor protein/histidine kinases. Signal transducing histidine kinases are the key elements in two-component signal transduction systems, which control complex proc [...]
CDM67639.1 protein networkhttps://string-db.org/network/1216932.CM240_0474Hypothetical protein.
CDM67640.1 protein networkhttps://string-db.org/network/1216932.CM240_0475Hypothetical protein; Family membership.
CDM67641.1 protein networkhttps://string-db.org/network/1216932.CM240_0476Hypothetical protein.
topB protein networkhttps://string-db.org/network/1216932.CM240_0477DNA topoisomerase 3; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of [...]
CDM67643.1 protein networkhttps://string-db.org/network/1216932.CM240_0478The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD-or NADP-dependent oxidoreductases; High confidence in function and spec [...]
CDM67644.1 protein networkhttps://string-db.org/network/1216932.CM240_0479Transcriptional regulator, AraC family; DNA-binding domain-containing protein, AraC-type; High confidence in function and specificity.
CDM67645.1 protein networkhttps://string-db.org/network/1216932.CM240_0480Hypothetical protein.
CDM67646.1 protein networkhttps://string-db.org/network/1216932.CM240_0481Aspartate transaminase; Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes,such as the covalent binding of the pyridoxal-phosphate group to a ly [...]
CDM67647.1 protein networkhttps://string-db.org/network/1216932.CM240_0482Putative phytase; High confidence in function and specificity.
CDM67648.1 protein networkhttps://string-db.org/network/1216932.CM240_0483Iron hydrogenase 1; Proteins containing this domain may be involved in the mechanism of biological hydrogen activation and contain 4FE-4S clusters. They can use molecular hydrogen for the reducti [...]
hisC1 protein networkhttps://string-db.org/network/1216932.CM240_0484Histidinol-phosphate aminotransferase; L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate; High confidence in function and specificity; Belongs to the [...]
CDM67650.1 protein networkhttps://string-db.org/network/1216932.CM240_0485Cation-transporting ATPase, P-type; P-ATPases function to transport a variety of different compounds, including ions and phospholipids,across a membrane using ATP hydrolysis for energy. There are [...]
cshA protein networkhttps://string-db.org/network/1216932.CM240_0486DEAD-box ATP-dependent RNA helicase CshA; May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. Unwinds dsRNA in both [...]
CDM67652.1 protein networkhttps://string-db.org/network/1216932.CM240_0487Peptidyl-prolyl cis-trans isomerase (PPIase or rotamase) is an enzyme that accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; [...]
CDM67653.1 protein networkhttps://string-db.org/network/1216932.CM240_0488Sirohydrochlorin cobaltochelatase; Anaerobic cobalamin biosynthetic cobalt chelatase,(CbiK), C-terminal domain. CbiK is part of the,cobalt-early path for cobalamin biosynthesis. It catalyzes, the [...]
cobB1 protein networkhttps://string-db.org/network/1216932.CM240_0489Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen so [...]
CDM67655.1 protein networkhttps://string-db.org/network/1216932.CM240_0490This is a family Precorrin-8X methylmutases also known as Precorrin isomerase, CbiC/CobH, This enzyme catalyses the reaction: Precorrin-8X <=> hydrogenobyrinate. This enzyme is part of the Cobala [...]
cbiD protein networkhttps://string-db.org/network/1216932.CM240_0491Putative cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
CDM67657.1 protein networkhttps://string-db.org/network/1216932.CM240_0492Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; Probably catalyzes the methylation of C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W-a; High confidence in function a [...]
CDM67658.1 protein networkhttps://string-db.org/network/1216932.CM240_0493precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; In many organisms, this protein is fused to the CbiE subunit. The fused protein, when found in organisms catalyzing the oxida [...]
cobI protein networkhttps://string-db.org/network/1216932.CM240_0494Precorrin-2 C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.
cbiF protein networkhttps://string-db.org/network/1216932.CM240_0495Putative cobalt-precorrin-4 C(11)-methyltransferase; Catalyzes the methylation of C-11 in cobalt-precorrin-4 to form cobalt-precorrin-5A; High confidence in function and specificity.
cbiG protein networkhttps://string-db.org/network/1216932.CM240_0496Cobalamin biosynthesis protein CbiG; The gene encoded has been designated cbiH but in fact represents a fusion between cbiH and cbiG. As other multi-functional proteins involved in cobalamin bios [...]
cbiH protein networkhttps://string-db.org/network/1216932.CM240_0497Methyltransferase that catalyzes the methylation of C-17 in cobalt-precorrin-3B to form cobalt-precorrin-4; High confidence in function and specificity.
CDM67663.1 protein networkhttps://string-db.org/network/1216932.CM240_0498Cobalt-precorrin-6x reductase; This enzyme catalyzes a step in cobalamin biosynthesis. It has been identified experimentally in Pseudomonas denitrificans and has been shown to be part of cobalami [...]
CDM67664.1 protein networkhttps://string-db.org/network/1216932.CM240_0499Hypothetical protein; High confidence in function and specificity.
CDM67665.1 protein networkhttps://string-db.org/network/1216932.CM240_0500Putative membrane protein.
CDM67666.1 protein networkhttps://string-db.org/network/1216932.CM240_0501Putative secreted protein.
CDM67667.1 protein networkhttps://string-db.org/network/1216932.CM240_0502Putative membrane protein; Family membership.
vanR3 protein networkhttps://string-db.org/network/1216932.CM240_0503Regulatory protein VanR; High confidence in function and specificity.
CDM67669.1 protein networkhttps://string-db.org/network/1216932.CM240_0504Hypothetical protein; Family membership.
CDM67670.1 protein networkhttps://string-db.org/network/1216932.CM240_0505MutS-like mismatch repair protein, ATPase; The mutS family of proteins is named after the Salmonella typhimurium MutS protein involved in mismatch repair; other members of the family included the [...]
CDM67671.1 protein networkhttps://string-db.org/network/1216932.CM240_0506Phage infection protein; High confidence in function and specificity.
CDM67672.1 protein networkhttps://string-db.org/network/1216932.CM240_0507Phage infection protein; YhgE/Pip N-terminal domain; TIGR03061; High confidence in function and specificity.
CDM67673.1 protein networkhttps://string-db.org/network/1216932.CM240_0508Hypothetical protein; High confidence in function and specificity.
CDM67674.1 protein networkhttps://string-db.org/network/1216932.CM240_0509Hypothetical protein; Family membership.
CDM67675.1 protein networkhttps://string-db.org/network/1216932.CM240_0510Glycosyl transferase, family 2; Diverse family, transferring sugar from UDP-glucose,UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol [...]
CDM67676.1 protein networkhttps://string-db.org/network/1216932.CM240_0511Anaerobic ribonucleoside-triphosphate reductase; In ribonucleotide reductase protein R1 from Escherichia coli this domain is located at the N terminus,and is composed mostly of helices. It forms [...]
CDM67677.1 protein networkhttps://string-db.org/network/1216932.CM240_0512Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radic [...]
CDM67678.1 protein networkhttps://string-db.org/network/1216932.CM240_0513Hypothetical protein; Family membership.
CDM67679.1 protein networkhttps://string-db.org/network/1216932.CM240_0514Zn-dependent hydrolase of the beta-lactamase fold protein.
CDM67680.1 protein networkhttps://string-db.org/network/1216932.CM240_0515Putative membrane protein; Family membership.
CDM67681.1 protein networkhttps://string-db.org/network/1216932.CM240_0516Hypothetical protein; Family membership.
ileS protein networkhttps://string-db.org/network/1216932.CM240_0517Isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such erro [...]
regA protein networkhttps://string-db.org/network/1216932.CM240_0518HTH-type transcriptional regulator RegA; Involved in the regulation of amylase production; High confidence in function and specificity.
CDM67684.1 protein networkhttps://string-db.org/network/1216932.CM240_0519Hypothetical protein; Family membership.
CDM67685.1 protein networkhttps://string-db.org/network/1216932.CM240_0520Hypothetical protein; High confidence in function and specificity.
CDM67686.1 protein networkhttps://string-db.org/network/1216932.CM240_0521Glycosyltransferase; These enzymes catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds; High confidence in function and [...]
uvrB protein networkhttps://string-db.org/network/1216932.CM240_0522UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnorm [...]
uvrA protein networkhttps://string-db.org/network/1216932.CM240_0523UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 [...]
CDM67689.1 protein networkhttps://string-db.org/network/1216932.CM240_0524Hypothetical protein; Family membership.
CDM67690.1 protein networkhttps://string-db.org/network/1216932.CM240_0525Cell cycle protein; A number of prokaryotic integral membrane proteins involved in cell cycle processes have been found to be structurally related; High confidence in function and specificity; Be [...]
CDM67691.1 protein networkhttps://string-db.org/network/1216932.CM240_0526Penicillin binding protein transpeptidase domain; High confidence in function and specificity.
uvrC protein networkhttps://string-db.org/network/1216932.CM240_0527UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible [...]
CDM67693.1 protein networkhttps://string-db.org/network/1216932.CM240_0528Putative phosphatase CLB_3435; The PHP (Polymerase and Histidinol Phosphatase) domain is a putative phosphoesterase domain; High confidence in function and specificity.
murB protein networkhttps://string-db.org/network/1216932.CM240_0529UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
CDM67695.1 protein networkhttps://string-db.org/network/1216932.CM240_0530Hypothetical protein; Family membership.
CDM67696.1 protein networkhttps://string-db.org/network/1216932.CM240_0531Hepn domain, putative; The crystal structure of the HEPN domain from the TM0613 protein of Thermotoga maritima indicates that it is structurally; High confidence in function and specificity.
CDM67697.1 protein networkhttps://string-db.org/network/1216932.CM240_0532The presence of 8-oxoguanine residues in DNA can give rise to G-C to T-A transversion mutations. This enzyme is found in archaeal, bacterial and eukaryotic species, and is specifically responsibl [...]
groS protein networkhttps://string-db.org/network/1216932.CM240_0533GroES protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
groL protein networkhttps://string-db.org/network/1216932.CM240_0534Heat shock protein 60; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
CDM67700.1 protein networkhttps://string-db.org/network/1216932.CM240_0535Bacterial Peptidase A24 N-domain family; This family is found at the N-terminus of the pre-pilin peptidases (PF01478). It's function has not been specifically determined; however some of the fami [...]
CDM67701.1 protein networkhttps://string-db.org/network/1216932.CM240_0536This family contains both type II and type IV P54907 pathway secretion proteins from bacteria. P07169 VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer sys [...]
CDM67702.1 protein networkhttps://string-db.org/network/1216932.CM240_0537Type II secretion system protein F; Proteins with this domain in form a platform for the machiney of the Type II secretion system, as well as the Type 4 pili and the archaeal flagella. This domai [...]
CDM67703.1 protein networkhttps://string-db.org/network/1216932.CM240_0538Fimbrial assembly family protein; PilN is a plasmid-encoded, lipoprotein which locates to the outer membrane of bacteria and are part of a thin pilus required only for liquid mating; Family membe [...]
CDM67704.1 protein networkhttps://string-db.org/network/1216932.CM240_0539This protein is required for the assembly of the type IV fimbria in P. aeruginosa and for a similar pilus-like structure in Synechocystis. It is also found in species such as Deinococcus describe [...]
CDM67705.1 protein networkhttps://string-db.org/network/1216932.CM240_0540Fimbrial assembly protein; PilN is a plasmid-encoded, lipoprotein which locates to the outer membrane of bacteria and are part of a thin pilus required only for liquid mating; Family membership.
CDM67706.1 protein networkhttps://string-db.org/network/1216932.CM240_0541Hypothetical protein; Family membership.
CDM67707.1 protein networkhttps://string-db.org/network/1216932.CM240_0542Putative membrane protein; Family membership.
CDM67708.1 protein networkhttps://string-db.org/network/1216932.CM240_0543Hypothetical protein; Family membership.
CDM67709.1 protein networkhttps://string-db.org/network/1216932.CM240_0544Hypothetical protein; Family membership.
CDM67710.1 protein networkhttps://string-db.org/network/1216932.CM240_0545Putative membrane protein.
guaB protein networkhttps://string-db.org/network/1216932.CM240_0546Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesi [...]
guaA protein networkhttps://string-db.org/network/1216932.CM240_0547GMP synthase; Catalyzes the synthesis of GMP from XMP.
CDM67713.1 protein networkhttps://string-db.org/network/1216932.CM240_05481-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (D [...]
CDM67714.1 protein networkhttps://string-db.org/network/1216932.CM240_0549Multimeric flavodoxin; NADPH-dependent FMN reductase (EC) reduces FMN and also reduces riboflavin and FAD, although more slowly. Members of this entry catalyse the reaction NAD(P)H + FMN = NAD(P) [...]
CDM67715.1 protein networkhttps://string-db.org/network/1216932.CM240_0550Hypothetical protein; Family membership.
CDM67716.1 protein networkhttps://string-db.org/network/1216932.CM240_0551Putative membrane protein.
CDM67717.1 protein networkhttps://string-db.org/network/1216932.CM240_0552Hypothetical protein.
CDM67718.1 protein networkhttps://string-db.org/network/1216932.CM240_0553Hypothetical protein; Family membership; Belongs to the sigma-70 factor family.
CDM67719.1 protein networkhttps://string-db.org/network/1216932.CM240_0554poly(A) polymerase; This enzyme adds the poly (A) tail to mRNA; High confidence in function and specificity.
nadE protein networkhttps://string-db.org/network/1216932.CM240_0555NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
CDM67721.1 protein networkhttps://string-db.org/network/1216932.CM240_0556Group 1 glycosyl transferase; Members of this family transfer activated sugars to a variety of substrates, including glycogen,Fructose-6-phosphate and lipopolysaccharides; High confidence in func [...]
prmA1 protein networkhttps://string-db.org/network/1216932.CM240_0557Ribosomal protein L11 methyltransferase; The role of L11 methylation in ribosome function is,as yet, unknown; High confidence in function and specificity.
CDM67723.1 protein networkhttps://string-db.org/network/1216932.CM240_0558UPF0042 nucleotide-binding protein; Displays ATPase and GTPase activities.
CDM67724.1 protein networkhttps://string-db.org/network/1216932.CM240_0559Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
whiA protein networkhttps://string-db.org/network/1216932.CM240_0560Putative sporulation transcription regulator WhiA; Involved in cell division and chromosome segregation.
CDM67726.1 protein networkhttps://string-db.org/network/1216932.CM240_0561Putative membrane protein.
CDM67727.1 protein networkhttps://string-db.org/network/1216932.CM240_0562Hypothetical protein; Family membership.
CDM67728.1 protein networkhttps://string-db.org/network/1216932.CM240_0563Hypothetical protein.
CDM67729.1 protein networkhttps://string-db.org/network/1216932.CM240_0564Hypothetical protein.
CDM67730.1 protein networkhttps://string-db.org/network/1216932.CM240_0565Putative membrane protein.
CDM67731.1 protein networkhttps://string-db.org/network/1216932.CM240_0566Hypothetical protein; Family membership.
CDM67732.1 protein networkhttps://string-db.org/network/1216932.CM240_0567Hypothetical protein.
CDM67733.1 protein networkhttps://string-db.org/network/1216932.CM240_0568Hypothetical protein; Family membership.
CDM67734.1 protein networkhttps://string-db.org/network/1216932.CM240_0569Hypothetical protein; Family membership.
CDM67735.1 protein networkhttps://string-db.org/network/1216932.CM240_0570Hypothetical protein; High confidence in function and specificity.
CDM67736.1 protein networkhttps://string-db.org/network/1216932.CM240_0571Hypothetical protein; Family membership.
CDM67737.1 protein networkhttps://string-db.org/network/1216932.CM240_0572Putative membrane protein.
CDM67738.1 protein networkhttps://string-db.org/network/1216932.CM240_0573Putative secreted protein.
dnaE protein networkhttps://string-db.org/network/1216932.CM240_0574DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain [...]
pfkA protein networkhttps://string-db.org/network/1216932.CM240_05756-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
pyk protein networkhttps://string-db.org/network/1216932.CM240_0576Pyruvate kinase catalyses the final step in glycolysis; High confidence in function and specificity.
gltB1 protein networkhttps://string-db.org/network/1216932.CM240_0577Glutamate synthase (GltS)1 is a key enzyme in the early stages of the assimilation of ammonia in bacteria,yeasts, and plants. In bacteria, L-glutamate is involved in osmoregulation, is the precur [...]
gltB3 protein networkhttps://string-db.org/network/1216932.CM240_0578Glutamate synthase [NADPH] small chain; One pathway for the assimilation of ammonia and glutamate biosynthesis involves glutamate synthase which transfers the amide group of glutamine to 2-oxoglu [...]
CDM67744.1 protein networkhttps://string-db.org/network/1216932.CM240_0579LacI family transcriptional regulator; These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family groups together a [...]
CDM67745.1 protein networkhttps://string-db.org/network/1216932.CM240_0580Glucokinase; The protein belonging to groups transcriptional repressors, sugar kinases and yet uncharacterised open reading frames.This group, known as ROK (Repressor,ORF,Kinase) includes the xyl [...]
exp5-1 protein networkhttps://string-db.org/network/1216932.CM240_0581PTS system glucose-specific EIICBA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphory [...]
CDM67747.1 protein networkhttps://string-db.org/network/1216932.CM240_0582Endonuclease/exonuclease/phosphatase family protein; This domain is found in a large number of proteins including magnesium dependent endonucleases and phosphatases involved in intracellular sign [...]
exp5-2 protein networkhttps://string-db.org/network/1216932.CM240_0583PTS system glucose-specific EIICBA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphory [...]
CDM67749.1 protein networkhttps://string-db.org/network/1216932.CM240_0584Mismatch repair protein MutS-like protein; Mismatch repair contributes to the overall fidelity of DNA replication and is essential for combating the adverse effects of damage to the genome. It in [...]
CDM67750.1 protein networkhttps://string-db.org/network/1216932.CM240_0585Putative membrane protein.
CDM67751.1 protein networkhttps://string-db.org/network/1216932.CM240_0586HTH DNA-binding protein; High confidence in function and specificity.
CDM67752.1 protein networkhttps://string-db.org/network/1216932.CM240_0587Putative membrane protein.
CDM67753.1 protein networkhttps://string-db.org/network/1216932.CM240_0588Hypothetical protein; High confidence in function and specificity.
CDM67754.1 protein networkhttps://string-db.org/network/1216932.CM240_0589Putative membrane protein; Family membership.
CDM67755.1 protein networkhttps://string-db.org/network/1216932.CM240_0590Hypothetical protein; Family membership.
metA protein networkhttps://string-db.org/network/1216932.CM240_0591Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
CDM67757.1 protein networkhttps://string-db.org/network/1216932.CM240_0592First proposed to be RNA methyltransferases by homology to the TrmA family. The member from Escherichia coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939; Hi [...]
CDM67758.1 protein networkhttps://string-db.org/network/1216932.CM240_0593Hypothetical protein; Family membership.
llaIM protein networkhttps://string-db.org/network/1216932.CM240_0594Modification methylase; Methylation of specific adenine residues; required for both restriction and modification activities. May recognize a non-palindromic sequence; High confidence in function [...]
CDM67760.1 protein networkhttps://string-db.org/network/1216932.CM240_0595Hypothetical protein; Family membership.
CDM67761.1 protein networkhttps://string-db.org/network/1216932.CM240_0596Hypothetical protein; High confidence in function and specificity.
CDM67762.1 protein networkhttps://string-db.org/network/1216932.CM240_0597Hypothetical protein.
CDM67763.1 protein networkhttps://string-db.org/network/1216932.CM240_0598Hypothetical protein; High confidence in function and specificity.
CDM67764.1 protein networkhttps://string-db.org/network/1216932.CM240_0599Hypothetical protein; High confidence in function and specificity.
CDM67765.1 protein networkhttps://string-db.org/network/1216932.CM240_0600rRNA biogenesis protein rrp5; High confidence in function and specificity.
CDM67766.1 protein networkhttps://string-db.org/network/1216932.CM240_0601Hypothetical protein; High confidence in function and specificity.
CDM67767.1 protein networkhttps://string-db.org/network/1216932.CM240_0602Hypothetical protein; High confidence in function and specificity.
L1 protein networkhttps://string-db.org/network/1216932.CM240_0603A DNA polymerase is a cellular or viral polymerase enzyme that synthesizes DNA molecules from their nucleotide building blocks. DNA polymerases are essential for DNA replication, and usually func [...]
CDM67769.1 protein networkhttps://string-db.org/network/1216932.CM240_0604Hypothetical protein; High confidence in function and specificity.
CDM67770.1 protein networkhttps://string-db.org/network/1216932.CM240_0605Hypothetical protein; High confidence in function and specificity.
CDM67771.1 protein networkhttps://string-db.org/network/1216932.CM240_0606This family contains several bacterial virulence-associated protein E like proteins; High confidence in function and specificity.
CDM67772.1 protein networkhttps://string-db.org/network/1216932.CM240_0607VRR-NUC domain-containing protein; High confidence in function and specificity.
CDM67773.1 protein networkhttps://string-db.org/network/1216932.CM240_0608Putative Phage-related DNA helicase; Proteins that contain this domain appear to be distantly related to the DEAX box helicases, however no helicase activity has ever been demonstrated for these [...]
CDM67774.1 protein networkhttps://string-db.org/network/1216932.CM240_0609Hypothetical protein; High confidence in function and specificity.
CDM67775.1 protein networkhttps://string-db.org/network/1216932.CM240_0610HNH endonuclease is found in bacteria and viruses. This family includes pyocins, colicins and anaredoxins; High confidence in function and specificity.
CDM67776.1 protein networkhttps://string-db.org/network/1216932.CM240_0611Hypothetical protein; High confidence in function and specificity.
CDM67777.1 protein networkhttps://string-db.org/network/1216932.CM240_0612Hypothetical protein; High confidence in function and specificity.
CDM67778.1 protein networkhttps://string-db.org/network/1216932.CM240_0613DNA-methyltransferase; The DNA methyltransferase (DNA MTase) family of enzymes catalyze the transfer of a methyl group to DNA. In prokaryotes, the major role of DNA methylation is to protect host [...]
CDM67779.1 protein networkhttps://string-db.org/network/1216932.CM240_0614C-5 cytosine-specific DNA methylases (EC) (C5 Mtase) are enzymes that specifically methylate the C-5 carbon of cytosines in DNA to produce C5-methylcytosine; High confidence in function and speci [...]
CDM67780.1 protein networkhttps://string-db.org/network/1216932.CM240_0615Hypothetical protein; High confidence in function and specificity.
CDM67781.1 protein networkhttps://string-db.org/network/1216932.CM240_0616Hypothetical protein; High confidence in function and specificity.
CDM67782.1 protein networkhttps://string-db.org/network/1216932.CM240_0617Phage terminase-like protein large subunit; This entry is represented by Lactococcus phage bIL285, Orf41 (terminase). The characteristics of the protein distribution suggest prophage matches in a [...]
CDM67783.1 protein networkhttps://string-db.org/network/1216932.CM240_0618Bacteriophage portal proteins form a dodecamer and is located at a five-fold vertex of the viral capsid. The portal complex forms a channel through which the viral DNA is packaged into the capsid [...]
CDM67784.2 protein networkhttps://string-db.org/network/1216932.CM240_0619Hypothetical protein; High confidence in function and specificity; Belongs to the peptidase S14 family.
CDM67785.1 protein networkhttps://string-db.org/network/1216932.CM240_0620Family of bacteriophage hypothetical proteins and capsid proteins; High confidence in function and specificity.
CDM67786.1 protein networkhttps://string-db.org/network/1216932.CM240_0621Hypothetical protein.
CDM67787.1 protein networkhttps://string-db.org/network/1216932.CM240_0622Hypothetical protein; High confidence in function and specificity.
CDM67788.1 protein networkhttps://string-db.org/network/1216932.CM240_0623Phi13 family phage major tail protein; This is a set of proteins that share low levels of sequence similarity but similar lengths and similar patterns of charged, hydrophobic, and Gly/Pro residue [...]
CDM67789.1 protein networkhttps://string-db.org/network/1216932.CM240_0624Hypothetical protein; High confidence in function and specificity.
CDM67790.1 protein networkhttps://string-db.org/network/1216932.CM240_0625Hypothetical protein; High confidence in function and specificity.
CDM67791.1 protein networkhttps://string-db.org/network/1216932.CM240_0626This family consists of several Siphovirus and other phage tail component proteins as well as some bacterial proteins of unknown function. The characteristics of the protein distribution suggest [...]
CDM67792.1 protein networkhttps://string-db.org/network/1216932.CM240_0627Phage minor structural protein; The characteristics of the protein distribution suggest prophage matches in addition to the phage matches; High confidence in function and specificity.
CDM67793.1 protein networkhttps://string-db.org/network/1216932.CM240_0628Hypothetical protein; High confidence in function and specificity.
CDM67794.2 protein networkhttps://string-db.org/network/1216932.CM240_0629O-Glycosyl hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety; High confide [...]
CDM67795.1 protein networkhttps://string-db.org/network/1216932.CM240_0630Toxin secretion/phage lysis holin; Phage holins and lytic enzymes are both necessary for bacterial lysis and virus dissemination.This family also includes TcdE/UtxA involved in toxin secretion in [...]
CDM67796.1 protein networkhttps://string-db.org/network/1216932.CM240_0631LysM domain-containing protein; This domain is about 40 residues long and is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglyca [...]
CDM67797.1 protein networkhttps://string-db.org/network/1216932.CM240_0632Hypothetical protein.
CDM67798.1 protein networkhttps://string-db.org/network/1216932.CM240_0633Serine Recombinase family, catalytic domain; a DNA,binding domain may be present either N-or C-terminal to,the catalytic domain. These enzymes perform site-specific,recombination of DNA molecules [...]
CDM67799.1 protein networkhttps://string-db.org/network/1216932.CM240_0634Recombinase; High confidence in function and specificity.
CDM67800.2 protein networkhttps://string-db.org/network/1216932.CM240_0635Resolvase; Serine Recombinase family, catalytic domain; a DNA,binding domain may be present either N-or C-terminal to,the catalytic domain. These enzymes perform site-specific,recombination of DN [...]
CDM67801.1 protein networkhttps://string-db.org/network/1216932.CM240_0636Hypothetical protein.
CDM67802.1 protein networkhttps://string-db.org/network/1216932.CM240_0637Hypothetical protein.
CDM67803.1 protein networkhttps://string-db.org/network/1216932.CM240_0638Methyl-accepting chemotaxis proteins (MCPs) are a family of bacterial receptors that mediate chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellent [...]
CDM67804.1 protein networkhttps://string-db.org/network/1216932.CM240_0639Hypothetical protein; Family membership.
CDM67805.1 protein networkhttps://string-db.org/network/1216932.CM240_0640Hypothetical protein.
CDM67806.1 protein networkhttps://string-db.org/network/1216932.CM240_0641Hypothetical protein.
CDM67807.1 protein networkhttps://string-db.org/network/1216932.CM240_0642Hypothetical protein.
CDM67808.1 protein networkhttps://string-db.org/network/1216932.CM240_0643Hypothetical protein; Family membership.
CDM67809.1 protein networkhttps://string-db.org/network/1216932.CM240_0644Hypothetical protein; Family membership.
CDM67810.1 protein networkhttps://string-db.org/network/1216932.CM240_0645C-5 cytosine-specific DNA methylases (C5 Mtase) are enzymes that specifically methylate the C-5 carbon of cytosines in DNA to produce C5-methylcytosine; High confidence in function and specificit [...]
CDM67811.1 protein networkhttps://string-db.org/network/1216932.CM240_0646C-5 cytosine-specific DNA methylases (EC) (C5 Mtase) are enzymes that specifically methylate the C-5 carbon of cytosines in DNA to produce C5-methylcytosine; High confidence in function and speci [...]
CDM67812.1 protein networkhttps://string-db.org/network/1216932.CM240_0647Hypothetical protein; Family membership.
CDM67813.1 protein networkhttps://string-db.org/network/1216932.CM240_0648This entry includes LlaJI which recognises GACGC restriction endonucleases; Hypothetical protein.
CDM67814.1 protein networkhttps://string-db.org/network/1216932.CM240_0649Hypothetical protein; High confidence in function and specificity.
CDM67815.1 protein networkhttps://string-db.org/network/1216932.CM240_0650Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif; High confidence in function and specificity.
CDM67816.1 protein networkhttps://string-db.org/network/1216932.CM240_0651Hypothetical protein.
CDM67817.1 protein networkhttps://string-db.org/network/1216932.CM240_0652rRNA biogenesis protein rrp5; High confidence in function and specificity.
CDM67818.1 protein networkhttps://string-db.org/network/1216932.CM240_0653Hypothetical protein; High confidence in function and specificity.
CDM67819.1 protein networkhttps://string-db.org/network/1216932.CM240_0654Hypothetical protein; High confidence in function and specificity.
L3 protein networkhttps://string-db.org/network/1216932.CM240_0655DNA-directed DNA polymerases are the key enzymes catalysing the accurate replication of DNA. They require either a small RNA molecule or a protein as a primer for the de novo synthesis of a DNA c [...]
CDM67821.1 protein networkhttps://string-db.org/network/1216932.CM240_0656Prophage antirepressor; This entry is represented by Bacteriophage P1,Ant1 C-terminal domain, which represents the processed Ant2 chain. The characteristics of the protein distribution suggest pr [...]
CDM67822.1 protein networkhttps://string-db.org/network/1216932.CM240_0657Hypothetical protein; High confidence in function and specificity.
CDM67823.1 protein networkhttps://string-db.org/network/1216932.CM240_0658This family contains several bacterial virulence-associated protein E like proteins; High confidence in function and specificity.
CDM67824.1 protein networkhttps://string-db.org/network/1216932.CM240_0659VRR-NUC domain-containing protein; It is associated with members of the PD-(D/E)XK nuclease superfamily, which include the type III restriction modification enzymes; High confidence in function a [...]
CDM67825.1 protein networkhttps://string-db.org/network/1216932.CM240_0660SNF2-like protein; SNF2 functions as the ATPase component of the SNF2/SWI multisubunit complex, which utilises energy derived from ATP hydrolysis to disrupt histone-DNA interactions, resulting in [...]
CDM67826.1 protein networkhttps://string-db.org/network/1216932.CM240_0661Hypothetical protein; High confidence in function and specificity.
CDM67827.1 protein networkhttps://string-db.org/network/1216932.CM240_0662HNH nucleases; HNH endonuclease signature which is,found in viral, prokaryotic, and eukaryotic proteins. The,alignment includes members of the large group of homing,endonucleases, yeast intron 1 [...]
CDM67828.1 protein networkhttps://string-db.org/network/1216932.CM240_0663Hypothetical protein; High confidence in function and specificity.
metK1 protein networkhttps://string-db.org/network/1216932.CM240_0664S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formati [...]
CDM67830.1 protein networkhttps://string-db.org/network/1216932.CM240_0665DNA methylase; In prokaryotes, the major role of DNA methylation is to protect host DNA against degradation by restriction enzymes. This family contains both N-4 cytosine-specific DNA methylases [...]
CDM67831.1 protein networkhttps://string-db.org/network/1216932.CM240_0666DNA-cytosine methyltransferase; C-5 cytosine-specific DNA methylases (EC) (C5 Mtase) are enzymes that specifically methylate the C-5 carbon of cytosines in DNA to produce C5-methylcytosine; High [...]
CDM67832.1 protein networkhttps://string-db.org/network/1216932.CM240_0667Hypothetical protein; High confidence in function and specificity.
CDM67833.1 protein networkhttps://string-db.org/network/1216932.CM240_0668Hypothetical protein; Family membership.
CDM67834.1 protein networkhttps://string-db.org/network/1216932.CM240_0669This family of proteins are likely to act as amidoligase enzymes Protein in this family are found in conserved gene neighborhoods encoding a glutamine amidotransferase-like thiol peptidase (in pr [...]
CDM67835.1 protein networkhttps://string-db.org/network/1216932.CM240_0670Hypothetical protein; High confidence in function and specificity.
CDM67836.1 protein networkhttps://string-db.org/network/1216932.CM240_0671Hypothetical protein.
CDM67837.1 protein networkhttps://string-db.org/network/1216932.CM240_0672Phage terminase family; The majority of the members of this family are bacteriophage proteins, several of which are thought to be terminase large subunit proteins. There are also a number of bact [...]
CDM67838.1 protein networkhttps://string-db.org/network/1216932.CM240_0673Phage portal protein, HK97 family; This is a family of bacteriophage, prophage and Gene Transfer Agent (GTA) portal proteins. Positioned at one of the twelve icosahedral vertices, of the viral ca [...]
CDM67839.1 protein networkhttps://string-db.org/network/1216932.CM240_0674Peptidase S14, ClpP; ClpP is an ATP-dependent protease that cleaves a number of proteins, such as casein and albumin. It exists as a heterodimer of ATP-binding regulatory A and catalytic P subuni [...]
CDM67840.1 protein networkhttps://string-db.org/network/1216932.CM240_0675Phage major capsid protein, HK97 family; The proteins in this family are found in bacteria and viruses (Caudovirales) and represent bacteriophage hypothetical proteins and capsid proteins; High c [...]
CDM67841.1 protein networkhttps://string-db.org/network/1216932.CM240_0676Hypothetical protein; Family membership.
CDM67842.1 protein networkhttps://string-db.org/network/1216932.CM240_0677Putative phage protein; High confidence in function and specificity.
CDM67843.1 protein networkhttps://string-db.org/network/1216932.CM240_0678The head-tail adaptor protein of bacteriophage SPP1 and related proteins in other bacteriophage and prophage regions of bacterial genomes; High confidence in function and specificity.
CDM67844.2 protein networkhttps://string-db.org/network/1216932.CM240_0679This protein represents a family of highly divergent putative prophage and bacteriophage proteins of unknown function. The family includes Gp10 from phages HK022 and HK97; High confidence in func [...]
CDM67845.1 protein networkhttps://string-db.org/network/1216932.CM240_0680Hypothetical protein; High confidence in function and specificity.
CDM67846.1 protein networkhttps://string-db.org/network/1216932.CM240_0681Phage major tail protein, phi13 family; TIGR01603; High confidence in function and specificity.
CDM67847.1 protein networkhttps://string-db.org/network/1216932.CM240_0682Hypothetical protein; High confidence in function and specificity.
CDM67848.1 protein networkhttps://string-db.org/network/1216932.CM240_0683Phage tape measure protein; Proteins containing this domain are strictly bacterial, including bacteriophage and prophage regions of bacterial genomes. Most members are 800 to 1800 amino acids lon [...]
CDM67849.1 protein networkhttps://string-db.org/network/1216932.CM240_0684Putative phage tail component; Phage-related protein [Function unknown]; High confidence in function and specificity.
CDM67850.1 protein networkhttps://string-db.org/network/1216932.CM240_0685Phage minor structural protein; The characteristics of the protein distribution suggest prophage matches in addition to the phage matches; High confidence in function and specificity.
CDM67851.1 protein networkhttps://string-db.org/network/1216932.CM240_0686Hypothetical protein; Family membership.
CDM67852.1 protein networkhttps://string-db.org/network/1216932.CM240_0687Hypothetical protein; High confidence in function and specificity.
CDM67853.1 protein networkhttps://string-db.org/network/1216932.CM240_0688Glycosyl hydrolase-like protein; Glycoside hydrolase family 18 is a family of glycoside hydrolases.Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic b [...]
CDM67854.1 protein networkhttps://string-db.org/network/1216932.CM240_0689Toxin secretion/phage lysis holin; Phage holins and lytic enzymes are both necessary for bacterial lysis and virus dissemination.This family also includes TcdE/UtxA involved in toxin secretion in [...]
CDM67855.1 protein networkhttps://string-db.org/network/1216932.CM240_0690N-acetylmuramoyl-L-alanine amidase is an enzyme that catalyzes a chemical reaction that cleaves the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopept [...]
CDM67856.1 protein networkhttps://string-db.org/network/1216932.CM240_0691Hypothetical protein; Family membership.
CDM67857.1 protein networkhttps://string-db.org/network/1216932.CM240_0692Resolvase domain-containing protein; Groups enzymes which share the following structural characteristics: an N-terminal catalytic and dimerization domain that contains a conserved serine residue [...]
CDM67858.2 protein networkhttps://string-db.org/network/1216932.CM240_0693Recombinase; High confidence in function and specificity.
CDM67859.2 protein networkhttps://string-db.org/network/1216932.CM240_0694Resolvase domain-containing protein; Groups enzymes which share the following structural characteristics: an N-terminal catalytic and dimerization domain that contains a conserved serine residue [...]
CDM67860.1 protein networkhttps://string-db.org/network/1216932.CM240_0695Hypothetical protein.
CDM67861.1 protein networkhttps://string-db.org/network/1216932.CM240_0696Hypothetical protein; Family membership.
CDM67862.1 protein networkhttps://string-db.org/network/1216932.CM240_0697Hypothetica protein; High confidence in function and specificity.
CDM67863.1 protein networkhttps://string-db.org/network/1216932.CM240_0698Hypothetical protein.
CDM67864.1 protein networkhttps://string-db.org/network/1216932.CM240_0699Hypothetical protein; High confidence in function and specificity.
CDM67865.1 protein networkhttps://string-db.org/network/1216932.CM240_0700Multi antimicrobial extrusion protein (MATE) also known as multidrug and toxin extrusion or multidrug and toxic compound extrusion is a family of proteins which function as drug/sodium or proton [...]
thiM protein networkhttps://string-db.org/network/1216932.CM240_0701Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
thiDE protein networkhttps://string-db.org/network/1216932.CM240_0702Phosphomethylpyrimidine kinase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine mono [...]
CDM67868.1 protein networkhttps://string-db.org/network/1216932.CM240_0703Hypothetical protein; Family membership.
CDM67869.1 protein networkhttps://string-db.org/network/1216932.CM240_0704Hypothetical protein; Family membership.
CDM67870.1 protein networkhttps://string-db.org/network/1216932.CM240_0705Transcription regulator; This protein represents a subset of the winged helix domain superfamily which is predominantly found in bacterial proteins, though there are also some archaeal and eukary [...]
CDM67871.1 protein networkhttps://string-db.org/network/1216932.CM240_0706Hypothetical protein; Family membership.
CDM67872.1 protein networkhttps://string-db.org/network/1216932.CM240_0707The metallo-beta-lactamase protein fold is a protein domain contained in class B beta-lactamases and a number of other proteins .[1] These proteins include thiolesterases,members of the glyoxalas [...]
CDM67873.1 protein networkhttps://string-db.org/network/1216932.CM240_0708HAD family phosphatase; Haloacid dehalogenase-like hydrolases. The haloacid,dehalogenase-like (HAD) superfamily includes L-2-haloacid,dehalogenase, epoxide hydrolase,phosphoserine,phosphatase,pho [...]
CDM67874.1 protein networkhttps://string-db.org/network/1216932.CM240_0709Predicted permeases [General function prediction,only]; High confidence in function and specificity.
CDM67875.1 protein networkhttps://string-db.org/network/1216932.CM240_0710Hypothetical protein.
CDM67876.1 protein networkhttps://string-db.org/network/1216932.CM240_0711Xanthine/uracil permease family protein; Many members of this family are functionally uncharacterised and may transport other substrates. Members of this family have ten predicted transmembrane h [...]
htpG protein networkhttps://string-db.org/network/1216932.CM240_0712Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
CDM67878.1 protein networkhttps://string-db.org/network/1216932.CM240_0713Hypothetical protein; High confidence in function and specificity.
CDM67879.1 protein networkhttps://string-db.org/network/1216932.CM240_0714Hypothetical protein.
CDM67880.1 protein networkhttps://string-db.org/network/1216932.CM240_0715HD family hydrolase; The HD domain is a conserved protein domain. It is found in a superfamily of enzymes with a predicted or known phosphohydrolase activity. These enzymes appear to be involved [...]
CDM67881.1 protein networkhttps://string-db.org/network/1216932.CM240_0716Hypothetical protein.
CDM67882.1 protein networkhttps://string-db.org/network/1216932.CM240_0717O-acetylhomoserine (thiol)-lyase; High confidence in function and specificity.
CDM67883.1 protein networkhttps://string-db.org/network/1216932.CM240_0718Hypothetical protein; High confidence in function and specificity.
CDM67884.1 protein networkhttps://string-db.org/network/1216932.CM240_0719Hypothetical protein; Family membership.
lgt3 protein networkhttps://string-db.org/network/1216932.CM240_0720Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
CDM67886.1 protein networkhttps://string-db.org/network/1216932.CM240_0721Putative thioredoxin reductase; FAD flavoproteins belonging to the family of pyridine nucleotide-disulphide oxidoreductases (glutathione reductase, thioredoxin reductase, alkyl hydroperoxide redu [...]
ahpC protein networkhttps://string-db.org/network/1216932.CM240_0722Alkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role i [...]
CDM67888.1 protein networkhttps://string-db.org/network/1216932.CM240_0723Hypothetical protein.
CDM67889.1 protein networkhttps://string-db.org/network/1216932.CM240_0724S1 RNA binding domain protein; The S1 domain was originally identified in ribosomal protein S1 but is found in a large number of RNA-associated proteins. The structure of the S1 RNA-binding domai [...]
CDM67890.1 protein networkhttps://string-db.org/network/1216932.CM240_0725Putative membrane protein.
CDM67891.1 protein networkhttps://string-db.org/network/1216932.CM240_0726TspO/MBR family protein; Tryptophan-rich sensory protein (TspO) is an integral membrane protein that acts as a negative regulator of the expression of specific photosynthesis genes in response to [...]
CDM67892.1 protein networkhttps://string-db.org/network/1216932.CM240_0727Putative amidohydrolase; This enzymes represents a large metal dependent hydrolase superfamily; High confidence in function and specificity.
argS protein networkhttps://string-db.org/network/1216932.CM240_0728Arginine-tRNA ligase; The aminoacyl-tRNA synthetases catalyse the attachment of an amino acid to its cognate transfer RNA molecule in a highly specific two-step reaction. These proteins differ wi [...]
CDM67894.1 protein networkhttps://string-db.org/network/1216932.CM240_0729Hypothetical protein; Frameshift; Family membership; Belongs to the glycosyl hydrolase 13 family.
CDM67895.1 protein networkhttps://string-db.org/network/1216932.CM240_0730Putative membrane protein.
CDM67896.1 protein networkhttps://string-db.org/network/1216932.CM240_0731Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) [...]
CDM67897.1 protein networkhttps://string-db.org/network/1216932.CM240_0732This family includes FeoA a small protein,probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulator [...]
metN3 protein networkhttps://string-db.org/network/1216932.CM240_0733Methionine import ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
CDM67899.1 protein networkhttps://string-db.org/network/1216932.CM240_0734Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-m [...]
metQ protein networkhttps://string-db.org/network/1216932.CM240_0735D-methionine-binding lipoprotein MetQ; This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system; High confidence in function and specificit [...]
CDM67901.1 protein networkhttps://string-db.org/network/1216932.CM240_0736Hypothetical protein; High confidence in function and specificity.
CDM67902.1 protein networkhttps://string-db.org/network/1216932.CM240_0737Putative protein; Family membership.
CDM67903.1 protein networkhttps://string-db.org/network/1216932.CM240_0738Hypothetical protein; Family membership.
CDM67904.1 protein networkhttps://string-db.org/network/1216932.CM240_0739OmpA/MotB domain-containing protein; The OmpA domain is a conserved protein domain with a beta/alpha/beta/alpha-beta(2) structure found in the C-terminal region of many Gram-negative bacterial ou [...]
CDM67905.1 protein networkhttps://string-db.org/network/1216932.CM240_0740D-alanyl-D-alanine carboxypeptidase; pfam00768; Family membership; Belongs to the peptidase S11 family.
CDM67906.1 protein networkhttps://string-db.org/network/1216932.CM240_0741Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, [...]
CDM67907.1 protein networkhttps://string-db.org/network/1216932.CM240_0742Rrf2 family protein; This entry represents transcriptional regulators such as Desulfovibrio vulgaris Protein Rrf2, Escherichia coli IscR and Bacillus subtilis NsrR. Protein Rrf2 is a repressor of [...]
cysK1 protein networkhttps://string-db.org/network/1216932.CM240_0743Catalyzes the conversion of O-acetylserine (OAS) to cysteine through the elimination of acetate and addition of hydrogen sulfide; High confidence in function and specificity; Belongs to the cyste [...]
trpE protein networkhttps://string-db.org/network/1216932.CM240_0744Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first [...]
trpGD1 protein networkhttps://string-db.org/network/1216932.CM240_0745Anthranilate synthase component II; Enzyme that catalyzes the transfer of an alpha-amino group from an amino acid to an alpha-keto acid. The amino group is usually covalently bound by the prosthe [...]
trpD protein networkhttps://string-db.org/network/1216932.CM240_0746Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranila [...]
CDM67912.1 protein networkhttps://string-db.org/network/1216932.CM240_0747Indole-3-glycerol phosphate synthase catalyses the fourth step in the biosynthesis of tryptophan, the ring closure of 1-(2-carboxy-phenylamino)-1-deoxyribulose into indol-3-glycerol-phosphate; Hi [...]
trpF protein networkhttps://string-db.org/network/1216932.CM240_0748Phosphoribosylanthranilate isomerase is an enzyme that catalyzes the third step of tryptophan biosynthesis; Hypothetical protein; Belongs to the TrpF family.
trpB3 protein networkhttps://string-db.org/network/1216932.CM240_0749Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpA protein networkhttps://string-db.org/network/1216932.CM240_0750Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
CDM67916.1 protein networkhttps://string-db.org/network/1216932.CM240_0751Citrate synthase (CS) catalyzes the condensation of,acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form,citrate and coenzyme A (CoA), the first step in the,oxidative citric acid cycle (TCA or [...]
CDM67917.1 protein networkhttps://string-db.org/network/1216932.CM240_0752Putative membrane protein.
CDM67918.1 protein networkhttps://string-db.org/network/1216932.CM240_0753Hypothetical protein; High confidence in function and specificity; Belongs to the glycosyl hydrolase 57 family.
CDM67919.1 protein networkhttps://string-db.org/network/1216932.CM240_0754The M16 family of zinc peptidases comprises a pair of homologous domains that form two halves of a 'clam-shell' surrounding the active site. This entry represents this domain found in metallopept [...]
recX protein networkhttps://string-db.org/network/1216932.CM240_0755Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
CDM67921.1 protein networkhttps://string-db.org/network/1216932.CM240_0756Transglutaminase-like enzyme, putative cysteine protease; This domain is found in many proteins known to have transglutaminase activity, i.e. which cross-link proteins through an acyl-transfer re [...]
CDM67922.1 protein networkhttps://string-db.org/network/1216932.CM240_0757Hypothetical protein; Family membership.
CDM67923.1 protein networkhttps://string-db.org/network/1216932.CM240_0758Putative CoA-substrate-specific enzyme activase; High confidence in function and specificity.
valS protein networkhttps://string-db.org/network/1216932.CM240_0759Valine-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, i [...]
glnS protein networkhttps://string-db.org/network/1216932.CM240_0760Glutamine-tRNA ligase; The aminoacyl-tRNA synthetases (EC 6.1.1.) catalyse the attachment of an amino acid to its cognate transfer RNA molecule in a highly specific two-step reaction. These prote [...]
CDM67926.1 protein networkhttps://string-db.org/network/1216932.CM240_0761Hypothetical protein; Family membership.
CDM67927.1 protein networkhttps://string-db.org/network/1216932.CM240_0762Putative N-acetyltransferase; Acetyltransferase (or transacetylase) is a type of transferase enzyme that transfers an acetyl group; Family membership.
gltX protein networkhttps://string-db.org/network/1216932.CM240_0763Glutamate-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of [...]
CDM67929.1 protein networkhttps://string-db.org/network/1216932.CM240_0764Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Conversion of folates to polyglutamate derivatives. It prefers 5,10-methylenetetrahydrofolate,rather than 10-formyltetrahydrofola [...]
CDM67930.1 protein networkhttps://string-db.org/network/1216932.CM240_0765Hypothetical protein; High confidence in function and specificity.
CDM67931.1 protein networkhttps://string-db.org/network/1216932.CM240_0766Hypothetical protein.
CDM67932.1 protein networkhttps://string-db.org/network/1216932.CM240_0767Capsule chain length determinant protein; Capsular polysaccharide biosynthesis protein [Cell,envelope biogenesis, outer membrane}; High confidence in function and specificity.
CDM67933.1 protein networkhttps://string-db.org/network/1216932.CM240_0768Tyrosine-protein kinase etk; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrog [...]
CDM67934.1 protein networkhttps://string-db.org/network/1216932.CM240_0769Protein-tyrosine-phosphatase; Involved in the regulation of capsular polysaccharide biosynthesis; High confidence in function and specificity.
CDM67935.1 protein networkhttps://string-db.org/network/1216932.CM240_0770Glycosyltransferase; These enzymes catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. A classification of glycosyltra [...]
CDM67936.1 protein networkhttps://string-db.org/network/1216932.CM240_0771Hypothetical protein; High confidence in function and specificity.
CDM67937.1 protein networkhttps://string-db.org/network/1216932.CM240_0772Putative Glycosyl transferase family 2; The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes cat [...]
CDM67938.1 protein networkhttps://string-db.org/network/1216932.CM240_0773Putative glycosyl transferase; The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the [...]
CDM67939.1 protein networkhttps://string-db.org/network/1216932.CM240_0774Group 1 glycosyl transferase; Members of this family transfer activated sugars to a variety of substrates, including glycogen,Fructose-6-phosphate and lipopolysaccharides. Members of this family [...]
CDM67940.1 protein networkhttps://string-db.org/network/1216932.CM240_0775Putative membrane protein.
CDM67941.1 protein networkhttps://string-db.org/network/1216932.CM240_0776Hypothetical protein; Family membership.
CDM67942.1 protein networkhttps://string-db.org/network/1216932.CM240_0777Hypothetical protein; Family membership.
CDM67943.1 protein networkhttps://string-db.org/network/1216932.CM240_0778Polysaccharide biosynthesis protein; Members of this family are integral membrane proteins, and many are implicated in the production of polysaccharide. The family includes RfbX part of the O ant [...]
CDM67944.1 protein networkhttps://string-db.org/network/1216932.CM240_0779Hypothetical protein.
CDM67945.1 protein networkhttps://string-db.org/network/1216932.CM240_0780Hypothetical protein.
CDM67946.1 protein networkhttps://string-db.org/network/1216932.CM240_0781Hypothetical protein; Family membership.
CDM67947.1 protein networkhttps://string-db.org/network/1216932.CM240_0782Hypothetical protein; High confidence in function and specificity.
CDM67948.1 protein networkhttps://string-db.org/network/1216932.CM240_0783Putative polysaccharide deacetylase; Necessary to maintain spores after the late stage of sporulation. Might be involved in cortex formation; High confidence in function and specificity.
CDM67949.1 protein networkhttps://string-db.org/network/1216932.CM240_0784ssDNA-binding protein; The Escherichia coli single-strand binding protein (gene ssb), also known as the helix-destabilising protein,is a protein of 177 amino acids. It binds tightly,as a homotetr [...]
dapH protein networkhttps://string-db.org/network/1216932.CM240_07852,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
yugH protein networkhttps://string-db.org/network/1216932.CM240_0786Putative aminotransferase YugH; Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes,such as the covalent binding of the pyridoxal-phosphate group [...]
CDM67952.1 protein networkhttps://string-db.org/network/1216932.CM240_0787Hypothetical protein; Frameshift; Family membership.
CDM67953.1 protein networkhttps://string-db.org/network/1216932.CM240_0788Hypothetical protein; Frameshift; Family membership; Belongs to the glycosyl hydrolase 13 family.
CDM67954.1 protein networkhttps://string-db.org/network/1216932.CM240_0789Hypothetical protein; From: 1, To: 411, outside.
CDM67955.1 protein networkhttps://string-db.org/network/1216932.CM240_0790Hypothetical protein; Frameshift; Family membership.
azoR protein networkhttps://string-db.org/network/1216932.CM240_0791FMN-dependent NADH-azoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its act [...]
recQ protein networkhttps://string-db.org/network/1216932.CM240_0792ATP-dependent DNA helicase RecQ; Helicases have been classified in 5 superfamilies (SF1-SF5). For the two largest groups, commonly referred to as SF1 and SF2, a total of seven characteristic moti [...]
CDM67958.1 protein networkhttps://string-db.org/network/1216932.CM240_0793Putative AgrB-like protein; May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor; Belongs to the AgrB family.
CDM67959.1 protein networkhttps://string-db.org/network/1216932.CM240_0794Hypothetical protein.
hppA protein networkhttps://string-db.org/network/1216932.CM240_0795Putative K(+)-stimulated pyrophosphate-energized sodium pump; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs [...]
CDM67961.1 protein networkhttps://string-db.org/network/1216932.CM240_0796Response regulator; Some bacteria can contain up to as many as 200 two-component systems that need tight regulation to prevent unwanted cross-talk; High confidence in function and specificity.
CDM67962.1 protein networkhttps://string-db.org/network/1216932.CM240_0797Hypothetical protein; Family membership.
CDM67963.1 protein networkhttps://string-db.org/network/1216932.CM240_0798Putative protein.
CDM67964.1 protein networkhttps://string-db.org/network/1216932.CM240_0799Hypothetical protein.
CDM67965.1 protein networkhttps://string-db.org/network/1216932.CM240_0800Phosphoribosylpyrophosphate synthetase; Members of Phosphoribosyltransferase (PRT) are catalytic and are regulatory proteins involved in nucleotide synthesis and salvage. This includes a range of [...]
CDM67966.1 protein networkhttps://string-db.org/network/1216932.CM240_0801This domain called GIY-YIG is found in the amino terminal region of excinuclease abc subunit c (uvrC),bacteriophage T4 endonucleases segA, segB,segC,segD and segE; it is also found in putative en [...]
tdcB protein networkhttps://string-db.org/network/1216932.CM240_0802Threonine dehydratase, catabolic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and [...]
CDM67968.1 protein networkhttps://string-db.org/network/1216932.CM240_0803Putative protein; High confidence in function and specificity; Belongs to the UPF0178 family.
CDM67969.1 protein networkhttps://string-db.org/network/1216932.CM240_0804Methyl-accepting chemotaxis sensory transducer; These proteins undergo two covalent modifications: deamidation and reversible methylation. Attractants increase the level of methylation while repe [...]
CDM67970.1 protein networkhttps://string-db.org/network/1216932.CM240_0805Hypothetical protein; Family membership.
CDM67971.1 protein networkhttps://string-db.org/network/1216932.CM240_0806Putative ribonuclease HI; Ribonuclease H (RNase H) recognizes and cleaves the RNA strand of RNA-DNA heteroduplexes.In prokaryotes RNase H is involved in removing the RNA of RNA-DNA hybrids,partic [...]
nagA protein networkhttps://string-db.org/network/1216932.CM240_0807N-acetylglucosamine-6-phosphate deacetylase; Proteins containing this domain are enzymes from a large metal dependent hydrolase superfamily; High confidence in function and specificity.
CDM67973.1 protein networkhttps://string-db.org/network/1216932.CM240_0808Putative membrane protein.
CDM67974.1 protein networkhttps://string-db.org/network/1216932.CM240_0809This family includes a diverse range of phosphoesterases including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as [...]
CDM67975.1 protein networkhttps://string-db.org/network/1216932.CM240_0810Putative sortase B; Sortase refers to a group of prokaryotic enzymes that modify surface proteins by recognizing and cleaving a carboxyl-terminal sorting signal. For most substrates of sortase en [...]
CDM67976.1 protein networkhttps://string-db.org/network/1216932.CM240_0811Cys/Met metabolism PLP-dependent enzyme family is a family of proteins including enzymes involved in cysteine and methionine metabolism which use PLP (pyridoxal-5'-phosphate) as a cofactor; High [...]
CDM67977.1 protein networkhttps://string-db.org/network/1216932.CM240_0812Hypothetical protein; Family membership.
CDM67978.1 protein networkhttps://string-db.org/network/1216932.CM240_0813Hypothetical protein.
CDM67979.1 protein networkhttps://string-db.org/network/1216932.CM240_0814Hypothetical protein.
CDM67980.1 protein networkhttps://string-db.org/network/1216932.CM240_0815Putative secreted protein.
CDM67981.1 protein networkhttps://string-db.org/network/1216932.CM240_0816SNF2 family helicase; Helicases have been classified in 5 superfamilies (SF1-SF5). For the two largest groups, commonly referred to as SF1 and SF2, a total of seven characteristic motifs has been [...]
CDM67982.1 protein networkhttps://string-db.org/network/1216932.CM240_0817Hypothetical protein; Family membership.
CDM67983.1 protein networkhttps://string-db.org/network/1216932.CM240_0818Hypothetical protein; Family membership.
ftsH3 protein networkhttps://string-db.org/network/1216932.CM240_0819ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral memb [...]
CDM67985.1 protein networkhttps://string-db.org/network/1216932.CM240_0820Rubrerythrin (Rr), found in anaerobic sulphate-reducing bacteria [PUBMED:7830612], is a fusion protein containing an N-terminal diiron-binding domain and a C-terminal domain homologous to rubredo [...]
CDM67986.1 protein networkhttps://string-db.org/network/1216932.CM240_0821Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, [...]
CDM67987.1 protein networkhttps://string-db.org/network/1216932.CM240_0822Hypothetical protein; Family membership.
CDM67988.1 protein networkhttps://string-db.org/network/1216932.CM240_0823Putative Zn-dependent protease-like protein; Predicted Zn-dependent proteases and their,inactivated homologs [General function prediction only]; High confidence in function and specificity.
CDM67989.1 protein networkhttps://string-db.org/network/1216932.CM240_0824Hypothetical protein; High confidence in function and specificity.
CDM67990.1 protein networkhttps://string-db.org/network/1216932.CM240_0825Putative membrane protein.
ykwC protein networkhttps://string-db.org/network/1216932.CM240_08262-hydroxy-3-oxopropionate reductase catalyses the NAP(P)H dependent reduction of 2-hydroxy-3-oxopropionate (tartronate semialdehyde) to D-glycerate; High confidence in function and specificity.
CDM67992.1 protein networkhttps://string-db.org/network/1216932.CM240_0827Membrane protein; Family membership.
CDM67993.1 protein networkhttps://string-db.org/network/1216932.CM240_0828HAD family phosphatase; High confidence in function and specificity.
CDM67994.1 protein networkhttps://string-db.org/network/1216932.CM240_0829Hypothetical protein; Family membership.
CDM67995.1 protein networkhttps://string-db.org/network/1216932.CM240_0830Hypothetical protein; Family membership.
CDM67997.1 protein networkhttps://string-db.org/network/1216932.CM240_0833ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDM67998.1 protein networkhttps://string-db.org/network/1216932.CM240_0834Hypothetical protein.
CDM67999.1 protein networkhttps://string-db.org/network/1216932.CM240_0835Fe-S oxidoreductase; Radical SAM proteins catalyze diverse reactions,including unusual methylations,isomerization,sulphur insertion, ring formation, anaerobic oxidation and protein radical format [...]
CDM68000.1 protein networkhttps://string-db.org/network/1216932.CM240_0836Hypothetical protein; Family membership.
CDM68001.1 protein networkhttps://string-db.org/network/1216932.CM240_0837Beta-lactamases are enzymes produced by some bacteria that provide resistance to beta-lactam antibiotics like penicillins, cephamycins, and carbapenems (ertapenem),although carbapenems are relati [...]
CDM68002.2 protein networkhttps://string-db.org/network/1216932.CM240_0838Helicases have been classified in 5 superfamilies (SF1-SF5). All of the proteins bind ATP and,consequently,all of them carry the classical Walker A (phosphate-binding loop or P-loop) and Walker B [...]
CDM68003.1 protein networkhttps://string-db.org/network/1216932.CM240_0839Hypothetical protein; High confidence in function and specificity; Belongs to the peptidase S24 family.
CDM68004.1 protein networkhttps://string-db.org/network/1216932.CM240_0840Hypothetical protein; High confidence in function and specificity.
sau3AIM protein networkhttps://string-db.org/network/1216932.CM240_0841Modification methylase Sau3AI; High confidence in function and specificity.
CDM68006.1 protein networkhttps://string-db.org/network/1216932.CM240_0842There are four classes of restriction endonucleases: types I, II,III and IV. All types of enzymes recognise specific short DNA sequences and carry out the endonucleolytic cleavage of DNA to give [...]
CDM68007.1 protein networkhttps://string-db.org/network/1216932.CM240_0843HKD family nuclease/DNA/RNA helicase; Helicases have been classified in 5 superfamilies (SF1-SF5). For the two largest groups, commonly referred to as SF1 and SF2, a total of seven characteristic [...]
CDM68008.1 protein networkhttps://string-db.org/network/1216932.CM240_0844Hypothetical protein.
CDM68009.1 protein networkhttps://string-db.org/network/1216932.CM240_0845Hypothetical protein; Family membership.
CDM68010.1 protein networkhttps://string-db.org/network/1216932.CM240_0846Putative integral membrane protein; High confidence in function and specificity.
CDM68011.1 protein networkhttps://string-db.org/network/1216932.CM240_0847Nitroreductase family protein; This domain is characteristic of nitroreductase enzymes and related oxidoreductases. Members of this family utilise FMN as a cofactor and are often found to be homo [...]
CDM68012.1 protein networkhttps://string-db.org/network/1216932.CM240_0848Beta-lactamase domain-containing protein; Metallo-beta-lactamase superfamily; smart00849; High confidence in function and specificity.
CDM68013.1 protein networkhttps://string-db.org/network/1216932.CM240_0849Transcriptional regulator, ArsR family; The arsR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain present in transcription regulators of the arsR/smtB family, involved in s [...]
CDM68014.1 protein networkhttps://string-db.org/network/1216932.CM240_0850Putative membrane protein; Family membership.
CDM68015.1 protein networkhttps://string-db.org/network/1216932.CM240_0851Hypothetical protein; High confidence in function and specificity.
CDM68016.1 protein networkhttps://string-db.org/network/1216932.CM240_0852Hypothetical protein; Family membership.
CDM68017.1 protein networkhttps://string-db.org/network/1216932.CM240_0853Hypothetical protein; Family membership.
CDM68018.1 protein networkhttps://string-db.org/network/1216932.CM240_0854Hypothetical protein; Family membership.
CDM68019.1 protein networkhttps://string-db.org/network/1216932.CM240_0855Hypothetical protein; High confidence in function and specificity.
CDM68020.1 protein networkhttps://string-db.org/network/1216932.CM240_0856Hypothetical protein; Family membership.
CDM68021.1 protein networkhttps://string-db.org/network/1216932.CM240_0857Hypothetical protein; High confidence in function and specificity; Belongs to the UPF0251 family.
CDM68022.1 protein networkhttps://string-db.org/network/1216932.CM240_0858Transcriptional regulator, MerR family; The merR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 70 residues present in the merR family of transcriptional regulat [...]
CDM68023.1 protein networkhttps://string-db.org/network/1216932.CM240_0859Hypothetical protein; Family membership.
CDM68024.1 protein networkhttps://string-db.org/network/1216932.CM240_0860Hypothetical protein.
ytiB protein networkhttps://string-db.org/network/1216932.CM240_0861Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide. In Escherichia coli, CA (gene cynT) is involved in recycling carbon dioxide formed in t [...]
CDM68026.1 protein networkhttps://string-db.org/network/1216932.CM240_0862Peptidase, M24 family; This family contains metallopeptidases. It also contains non-peptidase homologues such as the N terminal domain of Spt16 which is a histone H3-H4 binding module; High confi [...]
CDM68027.1 protein networkhttps://string-db.org/network/1216932.CM240_0863Putative membrane protein.
CDM68028.1 protein networkhttps://string-db.org/network/1216932.CM240_0864DNAk protein; High confidence in function and specificity; Belongs to the heat shock protein 70 family.
CDM68029.1 protein networkhttps://string-db.org/network/1216932.CM240_0865Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the [...]
dnaK1 protein networkhttps://string-db.org/network/1216932.CM240_0866Chaperone protein DnaK; Members of this family are the chaperone DnaK, of the DnaK-DnaJ-GrpE chaperone system. All members of the seed alignment were taken from completely sequenced bacterial or [...]
CDM68031.1 protein networkhttps://string-db.org/network/1216932.CM240_0867Hypothetical protein; High confidence in function and specificity.
CDM68032.1 protein networkhttps://string-db.org/network/1216932.CM240_0868Hypothetical protein; Family membership.
CDM68033.1 protein networkhttps://string-db.org/network/1216932.CM240_0869Putative secreted protein.
sbcD protein networkhttps://string-db.org/network/1216932.CM240_0870Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' dou [...]
CDM68035.1 protein networkhttps://string-db.org/network/1216932.CM240_0871SMC domain protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' d [...]
CDM68036.1 protein networkhttps://string-db.org/network/1216932.CM240_0872Hypothetical protein; High confidence in function and specificity.
CDM68037.1 protein networkhttps://string-db.org/network/1216932.CM240_0873Hypothetical protein.
CDM68038.1 protein networkhttps://string-db.org/network/1216932.CM240_0874Putative cellulose synthase; These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are puta [...]
CDM68039.1 protein networkhttps://string-db.org/network/1216932.CM240_0875MgtC/SapB transporter; The MgtC protein is found in an operon with the Mg2+ transporter protein MgtB. The function of MgtC and its homologues is not known; High confidence in function and specifi [...]
CDM68040.2 protein networkhttps://string-db.org/network/1216932.CM240_0876Alpha amylase catalytic domain protein; Alpha amylase is classified as family 13 of the glycosyl hydrolases. The structure is an 8 stranded alpha/beta barrel containing the active site, interrupt [...]
CDM68041.1 protein networkhttps://string-db.org/network/1216932.CM240_0877Putative membrane protein; Family membership.
CDM68042.1 protein networkhttps://string-db.org/network/1216932.CM240_0878Hypothetical protein; Family membership.
CDM68043.1 protein networkhttps://string-db.org/network/1216932.CM240_0879Putative membrane protein.
CDM68044.1 protein networkhttps://string-db.org/network/1216932.CM240_0880This protein represents chromate transporters (CHR). These proteins reduce chromate accumulation and are essential for chromate resistance. They are composed of one or two copies of this region. [...]
CDM68045.1 protein networkhttps://string-db.org/network/1216932.CM240_0881This entry represents chromate transporters (CHR). These proteins reduce chromate accumulation and are essential for chromate resistance. They are composed of one or two copies of this region. Th [...]
CDM68046.1 protein networkhttps://string-db.org/network/1216932.CM240_0882ABC transporters belong to the ATP-Binding Cassette superfamily, which uses the hydrolysis of ATP to translocate a variety of compounds across biological membranes. ABC transporters are minimally [...]
CDM68047.1 protein networkhttps://string-db.org/network/1216932.CM240_0883Hypothetical protein; Family membership.
CDM68048.1 protein networkhttps://string-db.org/network/1216932.CM240_0884Sulfate transporter; A number of proteins involved in the transport of sulphate across a membrane as well as some yet uncharacterised proteins have been shown to be evolutionary related; High con [...]
CDM68049.1 protein networkhttps://string-db.org/network/1216932.CM240_0885Hypothetical protein; Family membership.
CDM68050.1 protein networkhttps://string-db.org/network/1216932.CM240_0886Putative membrane protein; High confidence in function and specificity.
ycaM protein networkhttps://string-db.org/network/1216932.CM240_0887Inner membrane transporter YcaM; Amino acid permeases are membrane permeases involved in the transport of amino acids into the cell. A number of such proteins have been found to be evolutionary r [...]
CDM68052.1 protein networkhttps://string-db.org/network/1216932.CM240_0888Putative membrane protein; Family membership.
CDM68053.1 protein networkhttps://string-db.org/network/1216932.CM240_0889The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD-or NADP-dependent oxidoreductases. As the first member of this family t [...]
CDM68054.1 protein networkhttps://string-db.org/network/1216932.CM240_0890Aminopeptidase 2; This group of metallopeptidases belong to MEROPS peptidase family M29 (aminopeptidase T family, clan M-). The protein fold of the peptidase domain and the active site residues a [...]
CDM68055.1 protein networkhttps://string-db.org/network/1216932.CM240_0891Hypothetical protein; High confidence in function and specificity.
CDM68056.1 protein networkhttps://string-db.org/network/1216932.CM240_0892Putative signal peptidase I; SPase I is an integral membrane protein that is anchored in the cytoplasmic membrane by one (in B. subtilis) or two (in E. coli) N-terminal transmembrane domains with [...]
CDM68057.1 protein networkhttps://string-db.org/network/1216932.CM240_0893Putative membrane protein.
CDM68058.1 protein networkhttps://string-db.org/network/1216932.CM240_0894Hypothetical protein; Family membership.
CDM68059.1 protein networkhttps://string-db.org/network/1216932.CM240_0895UvrD/REP helicase; Members of this family are helicases that catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA. THe family includes both Rep and UvrD helcases. The Re [...]
gapN1 protein networkhttps://string-db.org/network/1216932.CM240_0896NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; This protein belongs to the aldehyde dehydrogenase family.Aldehyde dehydrogenases are enzymes that oxidize a wide variety of aliphatic and [...]
CDM68061.1 protein networkhttps://string-db.org/network/1216932.CM240_0897Hypothetical protein.
CDM68062.1 protein networkhttps://string-db.org/network/1216932.CM240_0898Hypothetical protein.
czcD protein networkhttps://string-db.org/network/1216932.CM240_0899Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps [...]
apeB protein networkhttps://string-db.org/network/1216932.CM240_0900Putative M18 family aminopeptidase 2; The proteins have two catalytic zinc ions at the active site, bound by His/Asp, Asp, Glu, Asp/Glu and His. The catalysed reaction involves the release of an [...]
lysA protein networkhttps://string-db.org/network/1216932.CM240_0901Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
dapA2 protein networkhttps://string-db.org/network/1216932.CM240_09024-hydroxy-tetrahydrodipicolinate synthase 2; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
CDM68067.1 protein networkhttps://string-db.org/network/1216932.CM240_0903Hypothetical protein.
CDM68068.1 protein networkhttps://string-db.org/network/1216932.CM240_0904Putative lipoprotein; Family membership.
CDM68069.1 protein networkhttps://string-db.org/network/1216932.CM240_0905Putative membrane protein.
CDM68070.1 protein networkhttps://string-db.org/network/1216932.CM240_0906Glycosyltransferase 36; This domain is found in the NvdB protein, which is involved in the production of beta-(1->2)-glucan; High confidence in function and specificity.
CDM68071.1 protein networkhttps://string-db.org/network/1216932.CM240_0907Putative Phospholipase, patatin family; This domain is found in the patatin glycoproteins from the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymat [...]
CDM68072.1 protein networkhttps://string-db.org/network/1216932.CM240_0908Patatin-like phospholipase family protein; His domain is found in the patatin glycoproteins from the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzym [...]
ribD protein networkhttps://string-db.org/network/1216932.CM240_0909Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-termi [...]
CDM68074.1 protein networkhttps://string-db.org/network/1216932.CM240_0910Riboflavin synthase (RS-alpha) catalyzes the biosynthesis of riboflavin (vitamin B2) by dismutation of 6,7-dimethyl-8-(1'-D-ribityl)lumazine (Lum). Riboflavin synthases of bacteria and fungi are [...]
ribBA protein networkhttps://string-db.org/network/1216932.CM240_0911Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cycloh [...]
ribH protein networkhttps://string-db.org/network/1216932.CM240_09126,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
CDM68077.1 protein networkhttps://string-db.org/network/1216932.CM240_0913NAD-dependent epimerase/dehydratase; This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions [PUBMED:917 [...]
CDM68078.1 protein networkhttps://string-db.org/network/1216932.CM240_0914Putative membrane protein.
CDM68079.1 protein networkhttps://string-db.org/network/1216932.CM240_0915Hypothetical protein; Family membership.
CDM68080.1 protein networkhttps://string-db.org/network/1216932.CM240_0916Putative membrane protein.
CDM68081.1 protein networkhttps://string-db.org/network/1216932.CM240_0917Hypothetical protein.
CDM68082.1 protein networkhttps://string-db.org/network/1216932.CM240_0918Putative membrane protein.
trpS protein networkhttps://string-db.org/network/1216932.CM240_0919Tryptophan-tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
CDM68084.1 protein networkhttps://string-db.org/network/1216932.CM240_0920Putative membrane protein.
CDM68085.1 protein networkhttps://string-db.org/network/1216932.CM240_0921Radical SAM proteins catalyse diverse reactions,including unusual methylations,isomerisation,sulphur insertion, ring formation, anaerobic oxidation and protein radical formation; High confidence [...]
CDM68086.1 protein networkhttps://string-db.org/network/1216932.CM240_0922These transporters are proteins of about 280 residues and seem to contain six transmembrane regions. As signature patterns, we selected two conserved regions. The first one is located in what see [...]
CDM68087.1 protein networkhttps://string-db.org/network/1216932.CM240_0923Hypothetical protein.
CDM68088.1 protein networkhttps://string-db.org/network/1216932.CM240_0924Putative membrane protein.
yidA protein networkhttps://string-db.org/network/1216932.CM240_0925Phosphatase YidA; Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates erythrose 4-phosphate and mannose 1-phosphat [...]
CDM68090.1 protein networkhttps://string-db.org/network/1216932.CM240_0926Hypothetical protein; High confidence in function and specificity.
prfC protein networkhttps://string-db.org/network/1216932.CM240_0927Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for U [...]
CDM68092.1 protein networkhttps://string-db.org/network/1216932.CM240_0928Two CBS domain containing protein; CBS domains contain about 60 amino acid residues and occur as tandem pairs in a variety of proteins in bacteria,archaea, and eukaryotes. They are mainly found i [...]
CDM68093.1 protein networkhttps://string-db.org/network/1216932.CM240_0929Putative membrane protein.
tyrS protein networkhttps://string-db.org/network/1216932.CM240_0930Tyrosine-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRN [...]
CDM68095.1 protein networkhttps://string-db.org/network/1216932.CM240_0931Hypothetical protein.
CDM68096.1 protein networkhttps://string-db.org/network/1216932.CM240_0932Putative protein; Family membership.
CDM68097.1 protein networkhttps://string-db.org/network/1216932.CM240_0933Metallophosphoesterase; Protein with this domain is found in a diverse range of phosphoesterases, including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and [...]
CDM68098.1 protein networkhttps://string-db.org/network/1216932.CM240_0934Putative methyl-accepting chemotaxis sensory transducer; Methyl-accepting chemotaxis proteins (MCPs) are a family of bacterial receptors that mediate chemotaxis to diverse signals, responding to [...]
CDM68099.1 protein networkhttps://string-db.org/network/1216932.CM240_0935Hypothetical protein; High confidence in function and specificity.
yjbM protein networkhttps://string-db.org/network/1216932.CM240_0936GTP pyrophosphokinase YjbM; Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of [...]
CDM68101.1 protein networkhttps://string-db.org/network/1216932.CM240_0937RNA polymerase recruits alternative sigma factors as a means of switching on specific regulons. Most bacteria express a multiplicity of sigma factors. Two of these factors, sigma-70 (gene rpoD), [...]
CDM68102.1 protein networkhttps://string-db.org/network/1216932.CM240_0938Putative membrane protein.
CDM68103.1 protein networkhttps://string-db.org/network/1216932.CM240_0939This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6; High confidence i [...]
leuS protein networkhttps://string-db.org/network/1216932.CM240_0940Leucine-tRNA ligase; Aminoacyl-tRNA synthetases [1] are a group of enzymes which activate amino acids and transfer them to specific tRNA molecules as the first step in protein biosynthesis. In pr [...]
CDM68105.1 protein networkhttps://string-db.org/network/1216932.CM240_0941Putative membrane protein.
CDM68106.1 protein networkhttps://string-db.org/network/1216932.CM240_0942Putative membrane protein; Family membership.
CDM68107.1 protein networkhttps://string-db.org/network/1216932.CM240_0943Putative membrane protein.
CDM68108.1 protein networkhttps://string-db.org/network/1216932.CM240_0944Putative membrane protein.
CDM68109.1 protein networkhttps://string-db.org/network/1216932.CM240_0945Putative membrane protein.
CDM68110.1 protein networkhttps://string-db.org/network/1216932.CM240_0946DnaJ is a member of the hsp40 family of molecular chaperones, which is also called the J-protein family,the members of which regulate the activity of hsp70s. DnaJ (hsp40) binds to dnaK (hsp70) an [...]
CDM68111.1 protein networkhttps://string-db.org/network/1216932.CM240_0947Hypothetical protein; High confidence in function and specificity.
CDM68112.1 protein networkhttps://string-db.org/network/1216932.CM240_0948Adenylate cyclase; These sequences are functionally identified as members of the adenylate cyclase family, which catalyses the conversion of ATP to 3',5'-cyclic AMP and pyrophosphate. Six distinc [...]
CDM68113.1 protein networkhttps://string-db.org/network/1216932.CM240_0949Hypothetical protein; High confidence in function and specificity.
pepA protein networkhttps://string-db.org/network/1216932.CM240_0950Putative cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various [...]
CDM68115.1 protein networkhttps://string-db.org/network/1216932.CM240_0951Putative membrane protein; Family membership.
CDM68116.1 protein networkhttps://string-db.org/network/1216932.CM240_0952Putative membrane protein.
CDM68117.1 protein networkhttps://string-db.org/network/1216932.CM240_0953Putative transmembrane protein; High confidence in function and specificity.
CDM68118.1 protein networkhttps://string-db.org/network/1216932.CM240_0954Hypothetical protein; High confidence in function and specificity.
CDM68119.1 protein networkhttps://string-db.org/network/1216932.CM240_0955Hypothetical protein.
CDM68120.1 protein networkhttps://string-db.org/network/1216932.CM240_0956Putative membrane protein; Probably functions as a manganese efflux pump.
sdhB protein networkhttps://string-db.org/network/1216932.CM240_0957L-serine dehydratase (is a found as a heterodimer of alpha and beta chain or as a fusion of the two chains in a single protein. This enzyme catalyses the deamination of serine to form pyruvate. T [...]
sdaAA protein networkhttps://string-db.org/network/1216932.CM240_0958L-serine dehydratase (is a found as a heterodimer of alpha and beta chain or as a fusion of the two chains in a single protein. This enzyme catalyses the deamination of serine to form pyruvate. T [...]
CDM68123.1 protein networkhttps://string-db.org/network/1216932.CM240_0959Rubrerythrin; The rubredoxin-like domain is a 45-to 55-residue domain containing one iron atom tetrahedrally coordinated to four cysteinyl residues (Fe(S-Cys)4 center). It is involved in electron [...]
CDM68124.1 protein networkhttps://string-db.org/network/1216932.CM240_0960Hypothetical protein.
CDM68125.1 protein networkhttps://string-db.org/network/1216932.CM240_0961Hypothetical protein.
CDM68126.1 protein networkhttps://string-db.org/network/1216932.CM240_0962CDP-diacylglycerol/serine O-phosphatidyltransferase; All of these members have the ability to catalyse the displacement of CMP from a CDP-alcohol by a second alcohol with formation of a phosphodi [...]
BmrU protein networkhttps://string-db.org/network/1216932.CM240_0963Lipid kinase; Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. The catalytic domain is assumed from the finding of bacterial homologues. YegS is the Escherich [...]
CDM68128.1 protein networkhttps://string-db.org/network/1216932.CM240_0964Putative membrane protein.
CDM68129.1 protein networkhttps://string-db.org/network/1216932.CM240_0965UPF0313 protein; This domain is functionally uncharacterised. This domain is found in bacteria and archaea. This presumed domain is typically between 117 to 158 amino acids in length; High confid [...]
CDM68130.1 protein networkhttps://string-db.org/network/1216932.CM240_0966MgtE intracellular region; This domain is found at the N-terminus of eubacterial magnesium transporters of the MgtE family PF01769. This domain is an intracellular domain that has an alpha-helica [...]
cysE protein networkhttps://string-db.org/network/1216932.CM240_0967Serine O-acetyltransferase (SAT) (gene cysE), an enzyme involved in cysteine biosynthesis. Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine; High confidence in function and specificity.
CDM68132.1 protein networkhttps://string-db.org/network/1216932.CM240_0968The iron-sulfur proteins of the succinate dehydrogenase and the fumarate reductase complexes. These enzyme complexes, which are components of the tricarboxylic acid cycle, each contain three subu [...]
CDM68133.1 protein networkhttps://string-db.org/network/1216932.CM240_0969This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function.This domain is found in tafazzins, defects in which are the cause of Barth syndr [...]
nth protein networkhttps://string-db.org/network/1216932.CM240_0970Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- [...]
CDM68135.1 protein networkhttps://string-db.org/network/1216932.CM240_0971Hypothetical protein; Family membership.
CDM68136.1 protein networkhttps://string-db.org/network/1216932.CM240_0972Hypothetical protein; High confidence in function and specificity.
ddl3 protein networkhttps://string-db.org/network/1216932.CM240_0973D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
yeaC1 protein networkhttps://string-db.org/network/1216932.CM240_0974Putative protein YeaC; High confidence in function and specificity.
CDM68139.1 protein networkhttps://string-db.org/network/1216932.CM240_0975Hypothetical protein; Family membership.
CDM68140.1 protein networkhttps://string-db.org/network/1216932.CM240_0976Putative membrane protein; Family membership.
CDM68141.1 protein networkhttps://string-db.org/network/1216932.CM240_0977HAD superfamily hydrolase; Haloacid dehalogenase-like hydrolases. The haloacid,dehalogenase-like (HAD) superfamily includes L-2-haloacid,dehalogenase, epoxide hydrolase,phosphoserine,phosphatase, [...]
CDM68142.1 protein networkhttps://string-db.org/network/1216932.CM240_0978Cof family hydrolase; The following uncharacterized proteins have been shown to share regions of similarities: Escherichia coli protein cof;Escherichia coli hypothetical protein ybhA and many oth [...]
CDM68143.1 protein networkhttps://string-db.org/network/1216932.CM240_0979Putative tRNA/rRNA methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltr [...]
CDM68144.1 protein networkhttps://string-db.org/network/1216932.CM240_0980The DegV protein family received its name based on sequence similarity to the DegV protein from Bacillus subtilis. All members of the DegV family are from bacteria,mostly Firmicutes. The function [...]
CDM68145.1 protein networkhttps://string-db.org/network/1216932.CM240_0981This family contains the N-terminal domain of a family of multiple membrane-spanning proteins of Gram-positive bacteria. One member was shown to be a host protein essential for phage infection, s [...]
CDM68146.1 protein networkhttps://string-db.org/network/1216932.CM240_0982Bmp family lipoprotein; This is a family of basic membrane lipoproteins form Borrelia and various putative lipoproteins form other bacteria. All of these proteins are outer membrane proteins and [...]
CDM68147.1 protein networkhttps://string-db.org/network/1216932.CM240_0983This is a family of basic membrane lipoproteins from Borrelia and various putative lipoproteins from other bacteria. All of these proteins are outer membrane proteins and are thus antigenic in na [...]
yufO protein networkhttps://string-db.org/network/1216932.CM240_0984ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM68149.1 protein networkhttps://string-db.org/network/1216932.CM240_0985Sugar ABC transporter, permease protein; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as Escherichia coli LivH and both of which are [...]
CDM68150.1 protein networkhttps://string-db.org/network/1216932.CM240_0986Putative ABC transporter, permease protein; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM both of which are f [...]
cggR protein networkhttps://string-db.org/network/1216932.CM240_0987Central glycolytic genes regulator; In the absence of glucose, represses the transcription of the gapA operon, which encodes five key glycolytic enzymes; High confidence in function and specifici [...]
gap protein networkhttps://string-db.org/network/1216932.CM240_0988Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is a tetrameric NAD-binding enzyme common to both the glycolytic and gluconeogenic pathways. A cysteine in the middle of the molecule is involved [...]
pgk protein networkhttps://string-db.org/network/1216932.CM240_0989Phosphoglycerate kinase catalyzes the second step in the second phase of glycolysis, the reversible conversion of 1,3-diphospho-glycerate to 3-phosphoglycerate with generation of one molecule of [...]
tpiA protein networkhttps://string-db.org/network/1216932.CM240_0990Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
gpmI protein networkhttps://string-db.org/network/1216932.CM240_09912,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
CDM68156.1 protein networkhttps://string-db.org/network/1216932.CM240_0992Putative membrane protein; Family membership.
CDM68157.1 protein networkhttps://string-db.org/network/1216932.CM240_0993Hypothetical protein; High confidence in function and specificity.
CDM68158.1 protein networkhttps://string-db.org/network/1216932.CM240_0994Putative membrane protein.
eno protein networkhttps://string-db.org/network/1216932.CM240_0995Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
CDM68160.1 protein networkhttps://string-db.org/network/1216932.CM240_0996Hypothetical protein; High confidence in function and specificity.
CDM68161.1 protein networkhttps://string-db.org/network/1216932.CM240_0997Putative membrane protein; High confidence in function and specificity.
CDM68162.1 protein networkhttps://string-db.org/network/1216932.CM240_0998Putative membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
rnr protein networkhttps://string-db.org/network/1216932.CM240_0999Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
smpB protein networkhttps://string-db.org/network/1216932.CM240_1000SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
ytjP protein networkhttps://string-db.org/network/1216932.CM240_1001Putative dipeptidase YtjP; The following enzymes have been shown to be evolutionary and functionally related: Xaa-His dipeptidase (carnosinase) from Lactobacillus (gene pepV), a metalloenzyme wit [...]
CDM68166.1 protein networkhttps://string-db.org/network/1216932.CM240_1002Putative protein.
CDM68167.1 protein networkhttps://string-db.org/network/1216932.CM240_1003Hypothetical protein; Frameshift; Family membership.
CDM68168.1 protein networkhttps://string-db.org/network/1216932.CM240_1004Signal transduction histidine kinase regulating citrate/malate metabolism; This domain is found in several ATP-binding proteins for example: histidine kinase, DNA gyrase B,topoisomerases,heat sho [...]
CDM68169.1 protein networkhttps://string-db.org/network/1216932.CM240_1005Two component transcriptional regulator, LytTR family; The LytTR domain is a DNA-binding, potential winged helix-turn-helix (wHTH) domain of about 100 amino acids,present in bacterial transcripti [...]
CDM68170.1 protein networkhttps://string-db.org/network/1216932.CM240_1006Putative membrane protein; Family membership.
CDM68171.1 protein networkhttps://string-db.org/network/1216932.CM240_1007Hypothetical protein; Family membership.
CDM68172.1 protein networkhttps://string-db.org/network/1216932.CM240_1008Members of this protein family are CoA-disulfide reductase, as characterized in Staphylococcus aureus,Pyrococcus horikoshii, and Borrelia burgdorferi,and inferred in several other species on the [...]
CDM68173.1 protein networkhttps://string-db.org/network/1216932.CM240_1009Sodium:dicarboxylate symporter family protein; It has been shown that integral membrane proteins that mediate the uptake of a wide variety of molecules with the concomitant uptake of sodium ions [...]
CDM68174.1 protein networkhttps://string-db.org/network/1216932.CM240_1010This entry represents mycolic acid cyclopropane synthases and related enzymes, including CmaA1, CmaA2 (cyclopropane mycolic acid synthase A1 and A2) and MmaA1-4 (methoxymycolic acid synthase A1-4 [...]
CDM68175.1 protein networkhttps://string-db.org/network/1216932.CM240_1011Pyridine nucleotide-disulphide oxidoreductase family protein; This is a family of conserved hypothetical proteins that may include proteins with a dinucleotide-binding motif (Rossman fold), inclu [...]
pbpC protein networkhttps://string-db.org/network/1216932.CM240_1012Penicillin-binding proteins (PBPs) are a group of proteins that are characterized by their affinity for and binding of penicillin. They are a normal constituent of many bacteria; the name just re [...]
CDM68177.1 protein networkhttps://string-db.org/network/1216932.CM240_1013Hypothetical protein.
CDM68178.1 protein networkhttps://string-db.org/network/1216932.CM240_1014Family of patatin-like phospholipases consists of various patatin glycoproteins from the total soluble protein from potato tubers, and also some proteins found in vertebrates. Patatin is a storag [...]
CDM68179.1 protein networkhttps://string-db.org/network/1216932.CM240_1015NLP/P60 protein; The function of this domain is unknown. It is found in several lipoproteins; Family membership.
CDM68180.1 protein networkhttps://string-db.org/network/1216932.CM240_1016Metallo-beta-lactamase family protein; Apart from the beta-lactamases a number of other proteins contain this domain. These proteins include thiolesterases, members of the glyoxalase II family, t [...]
CDM68181.1 protein networkhttps://string-db.org/network/1216932.CM240_1017Putative membrane protein.
CDM68182.1 protein networkhttps://string-db.org/network/1216932.CM240_1018Hypothetical protein; High confidence in function and specificity.
CDM68183.1 protein networkhttps://string-db.org/network/1216932.CM240_1019Hypothetical protein; Family membership.
CDM68184.1 protein networkhttps://string-db.org/network/1216932.CM240_1020Hypothetical protein; Family membership.
CDM68185.1 protein networkhttps://string-db.org/network/1216932.CM240_1021Hypothetical protein; High confidence in function and specificity.
CDM68186.1 protein networkhttps://string-db.org/network/1216932.CM240_1022Hypothetical protein; High confidence in function and specificity.
CDM68187.1 protein networkhttps://string-db.org/network/1216932.CM240_1023Putative membrane protein.
CDM68188.1 protein networkhttps://string-db.org/network/1216932.CM240_1024ErfK family protein; This family was formerly called the ErfK/YbiS/YcfS/YnhG family, but is now named after the first protein of known structure.This family of proteins are found in a range of ba [...]
CDM68189.1 protein networkhttps://string-db.org/network/1216932.CM240_1025Hypothetical protein.
CDM68190.1 protein networkhttps://string-db.org/network/1216932.CM240_1026Hypothetical protein; Family membership.
CDM68191.1 protein networkhttps://string-db.org/network/1216932.CM240_1027Hypopthetical protein; Family membership.
CDM68192.1 protein networkhttps://string-db.org/network/1216932.CM240_1028Putative secreted protein.
CDM68193.1 protein networkhttps://string-db.org/network/1216932.CM240_1029Protein of unknown function DUF939; This entry represents a C-terminal domain found in a set of bacterial proteins. The proteins are about 160 amino acids in length and are predicted to be multi- [...]
CDM68194.1 protein networkhttps://string-db.org/network/1216932.CM240_1030Putative membrane protein.
CDM68195.1 protein networkhttps://string-db.org/network/1216932.CM240_1031Hypothetical protein; Family membership.
CDM68196.1 protein networkhttps://string-db.org/network/1216932.CM240_1032AMP-forming long-chain acyl-CoA synthetase; A number of prokaryotic and eukaryotic enzymes,which appear to act via an ATP-dependent covalent binding of AMP to their substrate, share a region of s [...]
acpP protein networkhttps://string-db.org/network/1216932.CM240_1033Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
CDM68198.1 protein networkhttps://string-db.org/network/1216932.CM240_1034ABC-type antimicrobial peptide transport system; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transport [...]
CDM68199.1 protein networkhttps://string-db.org/network/1216932.CM240_1035aBC-type transport system; This entry represents the periplasmic core domain found in a variety of ABC transporters. The structure of this family has been solved for the MacB protein. Some struct [...]
CDM68200.1 protein networkhttps://string-db.org/network/1216932.CM240_1036Hypothetical protein.
CDM68201.1 protein networkhttps://string-db.org/network/1216932.CM240_1037Hypothetical protein.
CDM68202.1 protein networkhttps://string-db.org/network/1216932.CM240_1038Putative membrane protein; High confidence in function and specificity.
CDM68203.1 protein networkhttps://string-db.org/network/1216932.CM240_1039Hypothetical protein.
pyc protein networkhttps://string-db.org/network/1216932.CM240_1040Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate [...]
CDM68205.1 protein networkhttps://string-db.org/network/1216932.CM240_1041Hypothetical protein; High confidence in function and specificity.
CDM68206.1 protein networkhttps://string-db.org/network/1216932.CM240_1042Hypothetical protein; High confidence in function and specificity.
CDM68207.1 protein networkhttps://string-db.org/network/1216932.CM240_1043Hypothetical protein.
greA-2 protein networkhttps://string-db.org/network/1216932.CM240_1044Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
CDM68209.1 protein networkhttps://string-db.org/network/1216932.CM240_1045Putative membrane protein; High confidence in function and specificity.
CDM68210.1 protein networkhttps://string-db.org/network/1216932.CM240_1046Toxic anion resistance family protein; This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance and plasmid fertility inhibition; High [...]
CDM68211.1 protein networkhttps://string-db.org/network/1216932.CM240_1047Hypothetical protein; Family membership.
CDM68212.1 protein networkhttps://string-db.org/network/1216932.CM240_1048ABC1 family protein; This entry represents a domain found in Escherichia coli UbiB, known in Providencia stuartii as Aarf, which is required for the first monooxygenase step in ubiquinone (CoQ) b [...]
CDM68213.1 protein networkhttps://string-db.org/network/1216932.CM240_1049PTS system, IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS) [1,2] is a major carbohydrate transport system in bacteria. The PTS catalyzes the phosphorylat [...]
bglC protein networkhttps://string-db.org/network/1216932.CM240_10506-phospho-beta-glucosidase; Is able to catalyze the hydrolysis of aryl-phospho-beta-D-glucosides such as 4-methylumbelliferyl-phospho-beta-D-glucopyranoside (MUG-P), phosphoarbutin and phosphosal [...]
CDM68215.1 protein networkhttps://string-db.org/network/1216932.CM240_1051Hypothetical protein; High confidence in function and specificity.
CDM68216.1 protein networkhttps://string-db.org/network/1216932.CM240_1052Putative membrane protein.
CDM68217.1 protein networkhttps://string-db.org/network/1216932.CM240_1053methylated-DNA-protein- cysteinemethyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the m [...]
CDM68218.1 protein networkhttps://string-db.org/network/1216932.CM240_1054Beta-lactamase superfamily hydrolase; Apart from the beta-lactamases and metallo-beta-lactamases, a number of other proteins contain this domain. These proteins include thiolesterases, members of [...]
CDM68219.1 protein networkhttps://string-db.org/network/1216932.CM240_1055Putative membrane protein.
CDM68220.1 protein networkhttps://string-db.org/network/1216932.CM240_1056Hypothetical protein; Family membership.
CDM68221.1 protein networkhttps://string-db.org/network/1216932.CM240_1057Putative membrane protein; Family membership.
CDM68222.1 protein networkhttps://string-db.org/network/1216932.CM240_1058Putative membrane protein; High confidence in function and specificity.
CDM68223.1 protein networkhttps://string-db.org/network/1216932.CM240_1059Transposase; The retroviral integrase is the enzyme responsible for the insertion of a DNA copy of the viral genome into host DNA, an essential step in the replication cycle of viruses. Integrase [...]
CDM68224.1 protein networkhttps://string-db.org/network/1216932.CM240_1060Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS [...]
CDM68225.1 protein networkhttps://string-db.org/network/1216932.CM240_1061HAD-superfamily hydrolase; The Haloacid Dehydrogenase (HAD) superfamily includes phosphatases, phosphonatases, P-type ATPases,beta-phosphoglucomutases, phosphomannomutases, and dehalogenases, whi [...]
CDM68226.1 protein networkhttps://string-db.org/network/1216932.CM240_1062Na/Pi-cotransporter family protein/PhoU family protein; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria so [...]
CDM68227.1 protein networkhttps://string-db.org/network/1216932.CM240_1063HAD family hydrolase; The Haloacid Dehalogenase (HAD) superfamily is defined by the presence of three short catalytic motifs. The subfamilies are defined based on the location and the observed or [...]
CDM68228.1 protein networkhttps://string-db.org/network/1216932.CM240_1064Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate [...]
codB protein networkhttps://string-db.org/network/1216932.CM240_1065Cytosine permease; The Nucleobase Cation Symporter-1 (NCS1) family consists of bacterial and yeast transporters for nucleobases including purines and pyrimidines. Members of this family possess t [...]
codA protein networkhttps://string-db.org/network/1216932.CM240_1066Cytosine deaminase; Amidohydrolases are a diverse superfamily of enzymes which catalyse the hydrolysis of amide or amine bonds in a large number of different substrates including urea,cytosine, A [...]
fabV protein networkhttps://string-db.org/network/1216932.CM240_1067trans-2-enoyl-CoA reductase; Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (Co [...]
CDM68232.1 protein networkhttps://string-db.org/network/1216932.CM240_1068AraC-family transcriptional regulator; Many bacterial transcription regulation proteins bind DNA through a 'helix-turn-helix' (HTH) motif. One major subfamily of these proteins is related to the [...]
clpP1 protein networkhttps://string-db.org/network/1216932.CM240_1069ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
CDM68234.1 protein networkhttps://string-db.org/network/1216932.CM240_1070Hypothetical protein; Family membership.
CDM68235.1 protein networkhttps://string-db.org/network/1216932.CM240_1071GtrA family protein; Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharid [...]
CDM68236.1 protein networkhttps://string-db.org/network/1216932.CM240_1072Putative membrane protein; This is probably a bacterial ABC transporter permease; High confidence in function and specificity.
CDM68237.1 protein networkhttps://string-db.org/network/1216932.CM240_1073ybaK/ebsC protein; This domain is found either on its own or in association with the tRNA synthetase class II core domain (PF00587). It is involved in the tRNA editing of mis-charged tRNAs includ [...]
nfo protein networkhttps://string-db.org/network/1216932.CM240_1074Putative endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyri [...]
CDM68239.1 protein networkhttps://string-db.org/network/1216932.CM240_1075Hypothetical protein.
CDM68240.1 protein networkhttps://string-db.org/network/1216932.CM240_1076This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins; Family membership.
CDM68241.1 protein networkhttps://string-db.org/network/1216932.CM240_1077The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions from bacterial antibiotic resist [...]
CDM68242.1 protein networkhttps://string-db.org/network/1216932.CM240_1078Glutaredoxin-like protein; Glutaredoxins[1][2][3] are small redox enzymes of approximately one hundred amino-acid residues that use glutathione as a cofactor. Glutaredoxins are oxidized by substr [...]
CDM68243.1 protein networkhttps://string-db.org/network/1216932.CM240_1079Hypothetical protein; Frameshift; Family membership.
glxK protein networkhttps://string-db.org/network/1216932.CM240_1080This family includes glycerate kinase 2, which catalyses the phosphorylation of (R)-glycerate to 3-phospho-(R)-glycerate in the presence of ATP. These proteins consist of two different alpha/beta [...]
CDM68245.1 protein networkhttps://string-db.org/network/1216932.CM240_1081Putative membrane protein.
CDM68246.1 protein networkhttps://string-db.org/network/1216932.CM240_1082Hypothetical protein.
CDM68247.1 protein networkhttps://string-db.org/network/1216932.CM240_1083Pentapeptide repeats are a family of sequence motifs found in multiple tandem copies in protein molecules.Pentapeptide repeat proteins are found in all species, but they are found in many copies [...]
CDM68248.1 protein networkhttps://string-db.org/network/1216932.CM240_1084Hypothetical protein.
CDM68249.1 protein networkhttps://string-db.org/network/1216932.CM240_1085Putative protein.
CDM68250.1 protein networkhttps://string-db.org/network/1216932.CM240_1086Mechanosensitive (MS) channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation. They are present in the membranes [...]
CDM68251.1 protein networkhttps://string-db.org/network/1216932.CM240_1087Group 1 glycosyl transferase; The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the [...]
CDM68252.1 protein networkhttps://string-db.org/network/1216932.CM240_1088Hypothetical protein; High confidence in function and specificity.
CDM68253.1 protein networkhttps://string-db.org/network/1216932.CM240_1089Hypothetical protein; Family membership.
CDM68254.1 protein networkhttps://string-db.org/network/1216932.CM240_1090Glycosyl transferase family protein; The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes cataly [...]
CDM68255.1 protein networkhttps://string-db.org/network/1216932.CM240_1091Glycosyl transferase family protein; The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes cataly [...]
CDM68256.1 protein networkhttps://string-db.org/network/1216932.CM240_1092Group 1 glycosyl transferase; The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the [...]
CDM68257.1 protein networkhttps://string-db.org/network/1216932.CM240_1093Glycosyl transferase family protein; The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes cataly [...]
CDM68258.1 protein networkhttps://string-db.org/network/1216932.CM240_1094Hypothetical protein; Family membership.
rffA protein networkhttps://string-db.org/network/1216932.CM240_1095Lipopolysaccharide biosynthesis protein RffA; Sugar aminotransferase involved in enterobacterial common antigen (ECA) elongation; High confidence in function and specificity; Belongs to the DegT/ [...]
CDM68260.1 protein networkhttps://string-db.org/network/1216932.CM240_1096Hypothetical protein; Family membership.
CDM68261.1 protein networkhttps://string-db.org/network/1216932.CM240_1097Hypothetical protein; Family membership.
CDM68262.1 protein networkhttps://string-db.org/network/1216932.CM240_1098Putative membrane protein.
fba protein networkhttps://string-db.org/network/1216932.CM240_1099Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphat [...]
CDM68264.1 protein networkhttps://string-db.org/network/1216932.CM240_1100Pts system glucose-specific eiicba component; Sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. T [...]
CDM68265.1 protein networkhttps://string-db.org/network/1216932.CM240_1101PTS system, glucose-like IIB subunint; Sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The suga [...]
CDM68266.1 protein networkhttps://string-db.org/network/1216932.CM240_1102Peptidase M23 family; Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Pepti [...]
ftsE1 protein networkhttps://string-db.org/network/1216932.CM240_1103Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
CDM68268.1 protein networkhttps://string-db.org/network/1216932.CM240_1104Cell division protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family [...]
clpS protein networkhttps://string-db.org/network/1216932.CM240_1105ATP-dependent Clp protease adapter protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
clpA protein networkhttps://string-db.org/network/1216932.CM240_1106ATP-dependent specificity component of the ClpAP protease. It directs the protease to specific substrates. It has unfoldase activity. The primary function of the ClpA-ClpP complex appears to be t [...]
CDM68271.1 protein networkhttps://string-db.org/network/1216932.CM240_1107Chitinase A1 family protein; Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. From the view point of sequence similarity chi [...]
proA protein networkhttps://string-db.org/network/1216932.CM240_1108Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclizat [...]
CDM68273.1 protein networkhttps://string-db.org/network/1216932.CM240_1109Hypothetical protein; Family membership.
CDM68274.1 protein networkhttps://string-db.org/network/1216932.CM240_1110Trk system potassium uptake protein TrkH; This family consists of various cation transport proteins (Trk) and V-type sodium ATP synthase subunit J or translocating ATPase J These proteins are inv [...]
CDM68275.1 protein networkhttps://string-db.org/network/1216932.CM240_1111TrkA-N domain-containing protein; This domain is often found next to the PF02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligan [...]
CDM68276.1 protein networkhttps://string-db.org/network/1216932.CM240_1112Putative permease; This transmembrane region is found in putative permeases and predicted transmembrane proteins it has no known function. It is not clear what source suggested that these protein [...]
CDM68277.1 protein networkhttps://string-db.org/network/1216932.CM240_1113Protein of unknown function DUF815; High confidence in function and specificity.
CDM68278.1 protein networkhttps://string-db.org/network/1216932.CM240_1114Transcriptional regulator, AraC family; Many bacterial transcription regulation proteins bind DNA through a 'helix-turn-helix' (HTH) motif. One major subfamily of these proteins is related to the [...]
CDM68279.1 protein networkhttps://string-db.org/network/1216932.CM240_1115Cyclomaltodextrinase; High confidence in function and specificity; Belongs to the glycosyl hydrolase 13 family.
CDM68280.1 protein networkhttps://string-db.org/network/1216932.CM240_1116Putative Mn-containing catalase; This uncharacterized bacterial protein family has a ferritin-like domain; Family membership.
CDM68281.1 protein networkhttps://string-db.org/network/1216932.CM240_1117Hypothetical protein; High confidence in function and specificity.
CDM68282.1 protein networkhttps://string-db.org/network/1216932.CM240_1118Putative membrane protein.
CDM68283.1 protein networkhttps://string-db.org/network/1216932.CM240_1119Putative membrane protein.
CDM68284.1 protein networkhttps://string-db.org/network/1216932.CM240_1120Putative ammonium transporter sll0108; A number of proteins involved in the transport of ammonium ions across a membrane as well as some yet uncharacterized proteins have been shown to be evoluti [...]
CDM68285.1 protein networkhttps://string-db.org/network/1216932.CM240_1121P-II family proteins are regulators of nitrogen metabolism, with a length of 110 amino acid residues,found throughout the bacteria and most archaea. P-II proteins sense cellular 2-oxoglutarate as [...]
glnA protein networkhttps://string-db.org/network/1216932.CM240_1122Glutamine synthetase plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine; High confidence in function and specificity.
CDM68287.1 protein networkhttps://string-db.org/network/1216932.CM240_1123Response regulator receiver/ANTAR domain-containing protein; ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antiterminati [...]
CDM68288.1 protein networkhttps://string-db.org/network/1216932.CM240_1124Hypothetical protein; This entry represents a family of functionally uncharacterised proteins that are found in bacteria. Proteins in this family are approximately 190 amino acids in length; High [...]
CDM68289.1 protein networkhttps://string-db.org/network/1216932.CM240_1125Putative biotin synthase; Catalyzes the last step of the biotin biosynthesis pathway. All members of the seed alignment are in the immediate gene neighborhood of a bioA gene; Conserved hypothetic [...]
CDM68290.1 protein networkhttps://string-db.org/network/1216932.CM240_1126The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides, with a preference for [...]
hemA protein networkhttps://string-db.org/network/1216932.CM240_1127Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
CDM68292.1 protein networkhttps://string-db.org/network/1216932.CM240_1128Putative precorrin-2 dehydrogenase/oxidase; This domain is found in fungi, plants, archaea and bacteria; Family membership.
hemC protein networkhttps://string-db.org/network/1216932.CM240_1129Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
hemD protein networkhttps://string-db.org/network/1216932.CM240_1130Uroporphyrin-III C-methyltransferase (SUMT) catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the [...]
hemB protein networkhttps://string-db.org/network/1216932.CM240_1131Porphobilinogen synthase; Delta-aminolevulinic acid dehydratase (ALAD) catalyzes the second step in the biosynthesis of heme,the condensation of two molecules of 5-aminolevulinate to form porphob [...]
hemL protein networkhttps://string-db.org/network/1216932.CM240_1132Glutamate-1-semialdehyde aminotransferase (GSA). GSA is the enzyme involved in the second step of porphyrin biosynthesis, via the C5 pathway. It transfers the amino group on carbon 2 of glutamate [...]
CDM68297.1 protein networkhttps://string-db.org/network/1216932.CM240_1133The protein kinase domain is a structurally conserved protein domain containing the catalytic function of protein kinases.[2][3][4] Protein kinases are a group of enzymes that move a phosphate gr [...]
CDM68298.1 protein networkhttps://string-db.org/network/1216932.CM240_1134Putative membrane protein.
CDM68299.1 protein networkhttps://string-db.org/network/1216932.CM240_1135Hypothetical protein; Family membership.
CDM68300.1 protein networkhttps://string-db.org/network/1216932.CM240_1136Hypothetical protein; Family membership; Belongs to the WXG100 family.
CDM68301.1 protein networkhttps://string-db.org/network/1216932.CM240_1137Hypothetical protein; Family membership.
CDM68302.1 protein networkhttps://string-db.org/network/1216932.CM240_1138Hypothetical protein; Family membership.
CDM68303.1 protein networkhttps://string-db.org/network/1216932.CM240_1139Hypothetical protein; Family membership; Belongs to the WXG100 family.
CDM68304.1 protein networkhttps://string-db.org/network/1216932.CM240_1140Hypothetical protein.
CDM68305.1 protein networkhttps://string-db.org/network/1216932.CM240_1141This domain is found in protein phosphatase 2C, as well as other proteins eg. pyruvate dehydrogenase (lipoamide)-phosphatase, adenylate cyclase and some bacterial stage II sporulation E proteins; [...]
CDM68306.1 protein networkhttps://string-db.org/network/1216932.CM240_1142Putative membrane protein; Family membership.
CDM68307.1 protein networkhttps://string-db.org/network/1216932.CM240_1143MinD family ATPase from ParA/SOJ subfamily; AAA or AAA+ is an abbreviation for ATPases Associated with diverse cellular Activities. They share a common conserved module of approximately 230 amino [...]
CDM68308.1 protein networkhttps://string-db.org/network/1216932.CM240_1144Hypothetical protein.
CDM68309.1 protein networkhttps://string-db.org/network/1216932.CM240_1145DNA translocase FtsK; The FtsK domain contains a highly conserved putative ATP-binding P-loop motif and is assumed to be cytoplasmic. It can be found in one to three copies and is thought to be i [...]
CDM68310.1 protein networkhttps://string-db.org/network/1216932.CM240_1146Hypothetical protein; Family membership; Belongs to the WXG100 family.
CDM68311.1 protein networkhttps://string-db.org/network/1216932.CM240_1147Hypothetical protein; Family membership.
cobT protein networkhttps://string-db.org/network/1216932.CM240_1148Nicotinate-nucleotide- dimethylbenzimidazolephosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole ( [...]
CDM68313.1 protein networkhttps://string-db.org/network/1216932.CM240_1149cob(I)yrinic acid a,c-diamide adenosyltransferase (also known as ATP:cob(I)alamin or ATP:corrinoid adenosyltransferase)is an enzyme which catalyses the conversion of cobalamin (vitamin B12) into [...]
CDM68314.1 protein networkhttps://string-db.org/network/1216932.CM240_1150Putative Cobalbumin biosynthesis protein; This family is composed of a group of bifunctional cobalamin biosynthesis enzymes which display cobinamide kinase and cobinamide phosphate guanyltransfer [...]
cobS protein networkhttps://string-db.org/network/1216932.CM240_1151Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and [...]
CDM68316.1 protein networkhttps://string-db.org/network/1216932.CM240_1152This family is composed of a group of bifunctional cobalamin biosynthesis enzymes which display cobinamide kinase and cobinamide phosphate guanyltransferase activity. The crystal structure of the [...]
CDM68317.1 protein networkhttps://string-db.org/network/1216932.CM240_1153Phosphoglycerate mutase (PGAM) and bisphosphoglycerate mutase(BPGM) are structurally related enzymes that catalyse reactions involving the transfer of phospho groups between the three carbon atom [...]
cobD protein networkhttps://string-db.org/network/1216932.CM240_1154Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
CDM68319.1 protein networkhttps://string-db.org/network/1216932.CM240_1155Threonine-phosphate decarboxylase; Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin [...]
CDM68320.1 protein networkhttps://string-db.org/network/1216932.CM240_11562,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; Family membership.
CDM68321.1 protein networkhttps://string-db.org/network/1216932.CM240_1157Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of pe [...]
CDM68322.1 protein networkhttps://string-db.org/network/1216932.CM240_1158Iron chelate uptake ABC transporter, FeCT family,permease protein; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner compone [...]
CDM68323.1 protein networkhttps://string-db.org/network/1216932.CM240_1159ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDM68324.1 protein networkhttps://string-db.org/network/1216932.CM240_1160Conserved domain protein; High confidence in function and specificity.
cobQ protein networkhttps://string-db.org/network/1216932.CM240_1161Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for eac [...]
CDM68326.1 protein networkhttps://string-db.org/network/1216932.CM240_1162Putative membrane protein.
CDM68327.1 protein networkhttps://string-db.org/network/1216932.CM240_1163Nitroreductases are a family of evolutionarily related proteins involved in the reduction of nitrogen-containing compounds, including those containing the nitro functional group. Members of this [...]
CDM68328.1 protein networkhttps://string-db.org/network/1216932.CM240_1164Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins [General function prediction only; High confidence in function and specificity.
CDM68329.1 protein networkhttps://string-db.org/network/1216932.CM240_1165It is predicted that this family of proteins all perform a phosphoesterase function. It included the single stranded DNA exonuclease RecJ; High confidence in function and specificity.
CDM68330.1 protein networkhttps://string-db.org/network/1216932.CM240_1166Sodium/alanine symporter family protein; Sodium symporters can be divided by sequence and functional similarity into various groups. One such group is the sodium/alanine symporter family, the mem [...]
CDM68331.1 protein networkhttps://string-db.org/network/1216932.CM240_1167This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase. It [...]
CDM68332.1 protein networkhttps://string-db.org/network/1216932.CM240_1168ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
rex protein networkhttps://string-db.org/network/1216932.CM240_1169Redox-sensing transcriptional repressor rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
crt protein networkhttps://string-db.org/network/1216932.CM240_11703-hydroxbutyryl-CoA dehydratase (crotonase; EC), a bacterial enzyme involved in the butyrate/butanol-producing pathway; High confidence in function and specificity; Belongs to the enoyl-CoA hydra [...]
bcd protein networkhttps://string-db.org/network/1216932.CM240_1171Acyl-CoA dehydrogenase, short-chain specific; Acyl-CoA dehydrogenases are a family of flavoproteins that catalyse the alpha,beta-dehydrogenation of acyl-CoA thioesters to the corresponding trans [...]
etfB protein networkhttps://string-db.org/network/1216932.CM240_1172Electron transfer flavoproteins (ETFs) serve as specific electron acceptors for primary dehydrogenases,transferring the electrons to terminal respiratory systems. They can be functionally classif [...]
etfA protein networkhttps://string-db.org/network/1216932.CM240_1173He electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF [...]
hbd protein networkhttps://string-db.org/network/1216932.CM240_11743-hydroxyacyl-CoA dehydrogenase (HCDH) is an enzyme involved in fatty acid metabolism, it catalyzes the reduction of 3-hydroxyacyl-CoA to 3-oxoacyl-CoA. Most eukaryotic cells have 2 fatty-acid be [...]
CDM68339.1 protein networkhttps://string-db.org/network/1216932.CM240_1175Hypothetical protein.
trmB protein networkhttps://string-db.org/network/1216932.CM240_1176tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
CDM68341.1 protein networkhttps://string-db.org/network/1216932.CM240_11773-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongati [...]
CDM68342.1 protein networkhttps://string-db.org/network/1216932.CM240_1178Hypothetical protein; Family membership.
CDM68343.1 protein networkhttps://string-db.org/network/1216932.CM240_1179Aconitate hydratase; Aconitase [1] is the enzyme from the tricarboxylic acid cycle that catalyzes the reversible isomerization of citrate and isocitrate. Cis-aconitate is formed as an intermediar [...]
argG protein networkhttps://string-db.org/network/1216932.CM240_1180Argininosuccinate synthase (AS) is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinat [...]
argH protein networkhttps://string-db.org/network/1216932.CM240_1181Argininosuccinate lyase; Arginosuccinase, which catalyzes the formation of arginine and fumarate from argininosuccinate, the last step in the biosynthesis of arginine; High confidence in function [...]
CDM68346.1 protein networkhttps://string-db.org/network/1216932.CM240_1182Hypothetical protein; High confidence in function and specificity.
CDM68347.1 protein networkhttps://string-db.org/network/1216932.CM240_1183Putative membrane protein.
CDM68348.1 protein networkhttps://string-db.org/network/1216932.CM240_1184Transcriptional regulator, AsnC family; The asnC-type HTH domain is a DNA-binding,helix-turn-helix (HTH) domain of about 60 amino acids present in transcription regulators of the asnC/lrp family. [...]
CDM68349.1 protein networkhttps://string-db.org/network/1216932.CM240_1185Aminoacyl-tRNA synthetase, class II (D, K and N) (EC 6.1.1.) is a protein domain that catalyses the attachment of an amino acid to its cognate transfer RNA molecule in a highly specific two-step [...]
CDM68350.1 protein networkhttps://string-db.org/network/1216932.CM240_1186Putative membrane protein.
CDM68351.1 protein networkhttps://string-db.org/network/1216932.CM240_1187Putative membrane protein.
CDM68352.1 protein networkhttps://string-db.org/network/1216932.CM240_1188NLP/P60 protein; The function of this domain is unknown. It is found in several lipoproteins; Family membership.
CDM68353.1 protein networkhttps://string-db.org/network/1216932.CM240_1189Calcium-translocating P-type ATPase; Calcium (Ca++) ATPases (calcium pump) from the sarcoplasmic reticulum (SR), the endoplasmic reticulum (ER) and the plasma membrane; High confidence in functio [...]
CDM68354.1 protein networkhttps://string-db.org/network/1216932.CM240_1190Hypothetical protein; High confidence in function and specificity.
CDM68355.1 protein networkhttps://string-db.org/network/1216932.CM240_1191Hypothetical protein.
CDM68356.1 protein networkhttps://string-db.org/network/1216932.CM240_1192Hypothetical protein; High confidence in function and specificity.
CDM68357.1 protein networkhttps://string-db.org/network/1216932.CM240_1193Stage V sporulation protein B; Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of t [...]
CDM68358.1 protein networkhttps://string-db.org/network/1216932.CM240_1194Hypothetical protein; Family membership.
CDM68359.1 protein networkhttps://string-db.org/network/1216932.CM240_1195This domain conveys a zinc dependent phospholipase C activity. It is found in a monomeric phospholipase C of Bacillus cereus as well as in the alpha toxin of Clostridium perfringens and Clostridi [...]
CDM68360.1 protein networkhttps://string-db.org/network/1216932.CM240_1196Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC m [...]
CDM68361.1 protein networkhttps://string-db.org/network/1216932.CM240_1197Hypothetical protein; Family membership.
ntpI protein networkhttps://string-db.org/network/1216932.CM240_1198V-type sodium ATPase, I subunit; This article is about the vacuolar H+, ATPase. For the gastric H+/K+ATPase, see Hydrogen potassium ATPase. For the plant/fungal plasma membrane H+, ATPase, see Pr [...]
CDM68363.1 protein networkhttps://string-db.org/network/1216932.CM240_1199V-type ATPase, K subunit; Transmembrane ATPases are membrane-bound enzyme complexes/ion transporters that use ATP hydrolysis to drive the transport of protons across a membrane. Some transmembran [...]
CDM68364.1 protein networkhttps://string-db.org/network/1216932.CM240_1200V-type ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane; Family membership.
CDM68365.1 protein networkhttps://string-db.org/network/1216932.CM240_1201V-type sodium ATPase, C subunit; This family includes the AC39 subunit from vacuolar ATP synthase P32366 and the C subunit from archaebacterial ATP synthase. The family also includes subunit C fr [...]
atpF protein networkhttps://string-db.org/network/1216932.CM240_1202V-type sodium ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
atpA1 protein networkhttps://string-db.org/network/1216932.CM240_1203V-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta ch [...]
atpB1 protein networkhttps://string-db.org/network/1216932.CM240_1204V-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
atpD1 protein networkhttps://string-db.org/network/1216932.CM240_1205V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
CDM68370.1 protein networkhttps://string-db.org/network/1216932.CM240_1206The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA. [...]
fprA1 protein networkhttps://string-db.org/network/1216932.CM240_1207Flavo-diiron protein FprA1; Catalyzes the four-electron reduction of molecular oxygen to water. In fact, functions as the terminal component of an NADH oxidase (NADH:O2 oxidoreductase) when using [...]
cls1 protein networkhttps://string-db.org/network/1216932.CM240_1208Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
CDM68373.1 protein networkhttps://string-db.org/network/1216932.CM240_1209Flavoredoxin; This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial biolum [...]
rluB protein networkhttps://string-db.org/network/1216932.CM240_1210Responsible for synthesis of pseudouridine from uracil-2633 in 23S ribosomal RNA; High confidence in function and specificity; Belongs to the pseudouridine synthase RsuA family.
CDM68375.1 protein networkhttps://string-db.org/network/1216932.CM240_1211Transcriptional regulator, RpiR family; The rpiR-type HTH domain is a DNA-binding,helix-turn-helix (HTH) domain of about 75-80 amino acids present in prokaryotic regulators of transcription. The [...]
CDM68376.1 protein networkhttps://string-db.org/network/1216932.CM240_1212NAD(FAD)-utilizing dehydrogenase; This is a family of conserved hypothetical proteins that may include proteins with a dinucleotide-binding motif (Rossman fold), including oxidoreductases and deh [...]
cmk protein networkhttps://string-db.org/network/1216932.CM240_1213Cytidylate kinasecatalyses the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP; High confidence in function and specificity.
ispH protein networkhttps://string-db.org/network/1216932.CM240_12144-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethyl [...]
CDM68379.1 protein networkhttps://string-db.org/network/1216932.CM240_1215Acetyltransferase, GNAT family; Acetyltransferase (or transacetylase) is a type of transferase enzyme that transfers an acetyl group; Family membership.
CDM68380.1 protein networkhttps://string-db.org/network/1216932.CM240_1216Hypothetical protein.
miaB protein networkhttps://string-db.org/network/1216932.CM240_1217(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenos [...]
CDM68382.1 protein networkhttps://string-db.org/network/1216932.CM240_1218Hypothetical protein.
CDM68383.1 protein networkhttps://string-db.org/network/1216932.CM240_1219Hypothetical protein; High confidence in function and specificity.
CDM68384.1 protein networkhttps://string-db.org/network/1216932.CM240_1220Hypothetical protein; High confidence in function and specificity.
CDM68385.1 protein networkhttps://string-db.org/network/1216932.CM240_1221Hypothetical protein.
rluF protein networkhttps://string-db.org/network/1216932.CM240_1222Responsible for synthesis of pseudouridine from uracil-2604 in 23S ribosomal RNA. Can, to a small extent,also react with uracil-2605; High confidence in function and specificity; Belongs to the p [...]
CDM68387.1 protein networkhttps://string-db.org/network/1216932.CM240_1223Hypothetical protein.
CDM68388.1 protein networkhttps://string-db.org/network/1216932.CM240_1224Putative permease MJ0326; This family includes permeases for diverse substrates such as xanthine P42086 uracil P39766 and vitamin C Q9UGH3. However many members of this family are functionally un [...]
CDM68389.1 protein networkhttps://string-db.org/network/1216932.CM240_1225Hypothetical protein.
yisQ protein networkhttps://string-db.org/network/1216932.CM240_1226Putative transporter YisQ; High confidence in function and specificity.
mutS protein networkhttps://string-db.org/network/1216932.CM240_1227DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase act [...]
mutL protein networkhttps://string-db.org/network/1216932.CM240_1228DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchm [...]
miaA protein networkhttps://string-db.org/network/1216932.CM240_1229tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(di [...]
hfq protein networkhttps://string-db.org/network/1216932.CM240_1230RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and chang [...]
ynbB protein networkhttps://string-db.org/network/1216932.CM240_1231Aluminum resistance protein; This is a putative pyridoxal 5'-phosphate-dependent methionine gamma-lyase enzyme involved in methionine catabolism; High confidence in function and specificity.
CDM68396.1 protein networkhttps://string-db.org/network/1216932.CM240_12324'-phosphopantetheinyl transferase; Activates the five peptidyl carrier protein (PCP) domains of gramicidin synthase GrsAB, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) t [...]
lexA protein networkhttps://string-db.org/network/1216932.CM240_1233LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causin [...]
CDM68398.1 protein networkhttps://string-db.org/network/1216932.CM240_1234Hypothetical protein.
CDM68399.1 protein networkhttps://string-db.org/network/1216932.CM240_1235Integrase family protein; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine re [...]
CDM68400.1 protein networkhttps://string-db.org/network/1216932.CM240_1236Hypothetical protein; Family membership.
CDM68402.1 protein networkhttps://string-db.org/network/1216932.CM240_1238Hypothetical protein; Family membership.
CDM68403.1 protein networkhttps://string-db.org/network/1216932.CM240_1239Putative membrane protein; Family membership.
CDM68404.1 protein networkhttps://string-db.org/network/1216932.CM240_1240TetR-family transcriptional regulator; This entry represents a DNA-binding domain with a helix-turn-helix (HTH) structure that is found in several bacterial and archaeal transcriptional regulator [...]
CDM68406.1 protein networkhttps://string-db.org/network/1216932.CM240_1242The Nudix family is a protein family of phosphohydrolases.[1][2][3] Using water-mediated catalysis they break a phosphate bond in their substrate to create two products. Nudix stands for Nucleosi [...]
CDM68407.1 protein networkhttps://string-db.org/network/1216932.CM240_1243Putative acetyltransferase; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins; Family membership.
yvgN protein networkhttps://string-db.org/network/1216932.CM240_1244Oxidoreductase, aldo/keto reductase family protein; The aldo-keto reductase family [1,2] groups together a number of structurally and functionally related NADPH-dependent oxidoreductases as well [...]
CDM68409.1 protein networkhttps://string-db.org/network/1216932.CM240_1245Putative transcriptional regulator; The merR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 70 residues present in the merR family of transcriptional regulators. [...]
CDM68410.1 protein networkhttps://string-db.org/network/1216932.CM240_1246Putative membrane protein.
CDM68411.1 protein networkhttps://string-db.org/network/1216932.CM240_1247TetR family transcriptional regulator; The tetR-type HTH domain is a DNA-binding,helix-turn-helix (HTH) domain of about 60 residues present in the tetR family of prokaryotic transcription regulat [...]
CDM68412.1 protein networkhttps://string-db.org/network/1216932.CM240_1248ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDM68413.1 protein networkhttps://string-db.org/network/1216932.CM240_1249ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological import and export systems. ABC transporters are minimally con [...]
CDM68414.1 protein networkhttps://string-db.org/network/1216932.CM240_1250Putative membrane protein.
CDM68415.1 protein networkhttps://string-db.org/network/1216932.CM240_1251RecF/RecN/SMC domain protein; Family membership.
CDM68416.1 protein networkhttps://string-db.org/network/1216932.CM240_1252Hypothetical protein.
CDM68417.1 protein networkhttps://string-db.org/network/1216932.CM240_1253Hypothetical protein.
CDM68418.1 protein networkhttps://string-db.org/network/1216932.CM240_1254Hypothetical protein; Frameshift.
CDM68419.1 protein networkhttps://string-db.org/network/1216932.CM240_1255Transposon Tn7 transposition protein TnsC; TnsABC + TnsD promote high-frequency insertion of Tn7 into a specific target site known as att-Tn7 whereas TnsABC + TnsE promote low-frequency insertion [...]
CDM68420.1 protein networkhttps://string-db.org/network/1216932.CM240_1256Integrase comprises three domains capable of folding independently and whose three-dimensional structures are known. However, the manner in which the N-terminal,catalytic, and C-terminal domains [...]
CDM68421.1 protein networkhttps://string-db.org/network/1216932.CM240_1257TnsA endonuclease; The Tn7 transposase is composed of proteins TnsA and TnsB. DNA breakage at the 5' end of the transposon is carried out by TnsA, and breakage and joining at the 3' end is carrie [...]
CDM68422.1 protein networkhttps://string-db.org/network/1216932.CM240_1258The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-tu [...]
CDM68423.1 protein networkhttps://string-db.org/network/1216932.CM240_1259Hypothetical protein; Family membership.
CDM68424.2 protein networkhttps://string-db.org/network/1216932.CM240_1260Hypothetical protein; Family membership.
CDM68425.1 protein networkhttps://string-db.org/network/1216932.CM240_1261Hpothetical protein; Family membership.
CDM68426.1 protein networkhttps://string-db.org/network/1216932.CM240_1262Helicase, RecD/TraA family; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold; Family membership.
CDM68427.1 protein networkhttps://string-db.org/network/1216932.CM240_1263Hypothetical protein.
CDM68428.1 protein networkhttps://string-db.org/network/1216932.CM240_1264LtrC-like protein; The function is this domain is not known. It is often associated with a Toprim (topoisomerase-primase) domain; High confidence in function and specificity.
CDM68429.1 protein networkhttps://string-db.org/network/1216932.CM240_1265Hypothetical protein.
CDM68430.1 protein networkhttps://string-db.org/network/1216932.CM240_1266Putative membrane protein.
CDM68431.1 protein networkhttps://string-db.org/network/1216932.CM240_1267Hypothetical protein.
CDM68432.1 protein networkhttps://string-db.org/network/1216932.CM240_1268Hypothetical protein; Family membership.
CDM68433.1 protein networkhttps://string-db.org/network/1216932.CM240_1269Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens; High confidence in function and specificity.
CDM68434.1 protein networkhttps://string-db.org/network/1216932.CM240_1270IS66 Orf2 like; This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition; Family membership.
CDM68435.1 protein networkhttps://string-db.org/network/1216932.CM240_1271Hypothetical protein; Family membership.
CDM68436.1 protein networkhttps://string-db.org/network/1216932.CM240_1272Putative ATP-dependent Lon protease; Members of this entry are uncharacterised proteins sporadically distributed in bacteria and archaea, about 470 amino acids in length. Several members of this [...]
CDM68437.1 protein networkhttps://string-db.org/network/1216932.CM240_1273This family is a member of the Alkaline phosphatase clan; High confidence in function and specificity.
CDM68438.1 protein networkhttps://string-db.org/network/1216932.CM240_1274Type II restriction enzyme, methylase subunits [Defense mechanisms]; High confidence in function and specificity.
CDM68439.1 protein networkhttps://string-db.org/network/1216932.CM240_1275Hypothetical protein; High confidence in function and specificity.
CDM68440.1 protein networkhttps://string-db.org/network/1216932.CM240_1276Hypothetical protein; High confidence in function and specificity.
CDM68441.1 protein networkhttps://string-db.org/network/1216932.CM240_1277Hypothetical protein; High confidence in function and specificity.
CDM68442.1 protein networkhttps://string-db.org/network/1216932.CM240_1278Hypothetical protein; Family membership.
CDM68443.1 protein networkhttps://string-db.org/network/1216932.CM240_1279Hypothetical protein.
CDM68444.1 protein networkhttps://string-db.org/network/1216932.CM240_1280Hypothetical protein; High confidence in function and specificity.
CDM68445.1 protein networkhttps://string-db.org/network/1216932.CM240_1281Hypothetical protein; High confidence in function and specificity.
CDM68446.1 protein networkhttps://string-db.org/network/1216932.CM240_1282Cysteine synthase; Reaction catalysed O(3)-acetyl-L-serine + H(2)S <=> L-cysteine + acetate; High confidence in function and specificity; Belongs to the cysteine synthase/cystathionine beta- synt [...]
DJ1D protein networkhttps://string-db.org/network/1216932.CM240_1283Putative intracellular protease/amidase; Pyrococcus furiosus protease I (PfpI) is an intracellular cysteine peptidase, characterized by its stability and proposed to represent the predominant pro [...]
YisY protein networkhttps://string-db.org/network/1216932.CM240_1284AB hydrolase superfamily; The alpha/beta hydrolase fold is common to a number of hydrolytic enzymes of widely differing phylogenetic origin and catalytic function. The core of each enzyme is an a [...]
CDM68449.1 protein networkhttps://string-db.org/network/1216932.CM240_1285Hypothetical protein.
CDM68450.1 protein networkhttps://string-db.org/network/1216932.CM240_1286Hypothetical protein; High confidence in function and specificity.
CDM68451.1 protein networkhttps://string-db.org/network/1216932.CM240_1287Hypothetical protein; High confidence in function and specificity.
CDM68452.1 protein networkhttps://string-db.org/network/1216932.CM240_1289Glutaredoxin-like protein; Glutaredoxins are small redox enzymes of approximately one hundred amino-acid residues that use glutathione as a cofactor. Glutaredoxins are oxidized by substrates, and [...]
CDM68453.1 protein networkhttps://string-db.org/network/1216932.CM240_1290Thioredoxin + NADP+ = thioredoxin disulfide + NADPH; High confidence in function and specificity.
CDM68454.1 protein networkhttps://string-db.org/network/1216932.CM240_1291Putative secreted protein.
CDM68455.1 protein networkhttps://string-db.org/network/1216932.CM240_1292Bifunctional folate synthesis protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
CDM68456.1 protein networkhttps://string-db.org/network/1216932.CM240_1293Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate [...]
CDM68457.1 protein networkhttps://string-db.org/network/1216932.CM240_1294Hypothetical protein; Family membership.
CDM68458.1 protein networkhttps://string-db.org/network/1216932.CM240_12954-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate. Based on the information a [...]
pabB protein networkhttps://string-db.org/network/1216932.CM240_1296Aminodeoxychorismate synthase component 1; Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC),a precursor of p-aminobenzoate (PABA) and te [...]
trpGD3 protein networkhttps://string-db.org/network/1216932.CM240_1297Anthranilate synthase component II; Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first [...]
CDM68461.1 protein networkhttps://string-db.org/network/1216932.CM240_1298Metal-dependent phosphoesterase (PHP family) protein; The PHP (Polymerase and Histidinol Phosphatase) domain is a putative phosphoesterase domain; High confidence in function and specificity.
pheA protein networkhttps://string-db.org/network/1216932.CM240_1299Prephenate dehydratase; Inhibited by L-phenylalanine but not by L-tyrosine or L-tryptophan; High confidence in function and specificity.
apeA protein networkhttps://string-db.org/network/1216932.CM240_1300Putative aminopeptidase 1; High confidence in function and specificity.
CDM68464.1 protein networkhttps://string-db.org/network/1216932.CM240_13015-formyltetrahydrofolate cyclo-ligase or methenyl-THF synthetasecatalyses the interchange of 5-formyltetrahydrofolate (5-FTHF) to 5-10-methenyltetrahydrofolate, this requires ATP and Mg2+ [1]. 5- [...]
hprK protein networkhttps://string-db.org/network/1216932.CM240_1302HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-depend [...]
CDM68466.1 protein networkhttps://string-db.org/network/1216932.CM240_1303Hypothetical protein; Family membership.
CDM68467.1 protein networkhttps://string-db.org/network/1216932.CM240_1304This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin Q16635 the Barth syndrome gene; High confide [...]
CDM68468.1 protein networkhttps://string-db.org/network/1216932.CM240_1305The metallo-beta-lactamase protein fold is a protein domain contained in class B beta-lactamases and a number of other proteins .These proteins include thiolesterases,members of the glyoxalase II [...]
CDM68469.1 protein networkhttps://string-db.org/network/1216932.CM240_1306This family includes human glycogen branching enzyme P35573. This enzyme contains a number of distinct catalytic activities. It has been shown for the yeast homologue O93808 that mutations in thi [...]
pfkA2 protein networkhttps://string-db.org/network/1216932.CM240_13116-phosphofructokinase 2; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase t [...]
uppP protein networkhttps://string-db.org/network/1216932.CM240_1312Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
CDM68472.1 protein networkhttps://string-db.org/network/1216932.CM240_1313Putative membrane protein; High confidence in function and specificity.
CDM68473.1 protein networkhttps://string-db.org/network/1216932.CM240_1314Mur ligase family protein; The bacterial cell wall provides strength and rigidity to counteract internal osmotic pressure, and protection against the environment. The peptidoglycan layer gives th [...]
CDM68474.1 protein networkhttps://string-db.org/network/1216932.CM240_1315CobB/CobQ domain-containing protein glutamine amidotransferase; This group of enzymes was suggested to be related to the MinD family of ATPases involved in regulation of cell division in bacteria [...]
CDM68475.1 protein networkhttps://string-db.org/network/1216932.CM240_1316This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase. It [...]
clpB1 protein networkhttps://string-db.org/network/1216932.CM240_1317Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to t [...]
CDM68477.1 protein networkhttps://string-db.org/network/1216932.CM240_1318Putative protein; Family membership.
CDM68478.1 protein networkhttps://string-db.org/network/1216932.CM240_1319Hypothetical protein; High confidence in function and specificity.
CDM68479.1 protein networkhttps://string-db.org/network/1216932.CM240_1320Putative membrane protein.
CDM68480.1 protein networkhttps://string-db.org/network/1216932.CM240_1321Hypothetical protein.
glnA3 protein networkhttps://string-db.org/network/1216932.CM240_1322Glutamine synthetase is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine; High confidence in function [...]
CDM68482.1 protein networkhttps://string-db.org/network/1216932.CM240_1323Hemolysin III; Members of this family are integral membrane proteins. This family includes a protein with hemolytic activity from Bacillus cereus. It has been proposed that YOL002c encodes a Sacc [...]
CDM68483.1 protein networkhttps://string-db.org/network/1216932.CM240_1324Hypothetical protein.
CDM68484.1 protein networkhttps://string-db.org/network/1216932.CM240_1325Hypothetical protein.
argF protein networkhttps://string-db.org/network/1216932.CM240_1326Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
glmS protein networkhttps://string-db.org/network/1216932.CM240_1327Glutamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
CDM68487.1 protein networkhttps://string-db.org/network/1216932.CM240_1328Helicase, SNF2/RAD54 family; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that [...]
CDM68488.1 protein networkhttps://string-db.org/network/1216932.CM240_1329Helicase domain protein; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that thi [...]
CDM68489.1 protein networkhttps://string-db.org/network/1216932.CM240_1330Hypothetical protein.
CDM68490.1 protein networkhttps://string-db.org/network/1216932.CM240_1331Hypothetical protein; Family membership.
CDM68491.1 protein networkhttps://string-db.org/network/1216932.CM240_1332Putative membrane protein.
CDM68492.1 protein networkhttps://string-db.org/network/1216932.CM240_1333Putative membrane protein; Family membership.
CDM68493.1 protein networkhttps://string-db.org/network/1216932.CM240_1334Hypothetial membrane protein; Family membership.
CDM68494.1 protein networkhttps://string-db.org/network/1216932.CM240_1335Hypothetical protein; Family membership.
CDM68495.1 protein networkhttps://string-db.org/network/1216932.CM240_1336Putative memrbane protein; Family membership.
CDM68496.1 protein networkhttps://string-db.org/network/1216932.CM240_1337Cell division protein; Family membership.
CDM68497.2 protein networkhttps://string-db.org/network/1216932.CM240_1338Type IV leader peptidase family protein; This family is found at the N-terminus of the pre-pilin peptidases (PF01478). It's function has not been specifically determined; however some of the fami [...]
CDM68498.1 protein networkhttps://string-db.org/network/1216932.CM240_1339Putative membrane protein; Family membership.
CDM68499.1 protein networkhttps://string-db.org/network/1216932.CM240_1340Hypothetical protein.
CDM68500.1 protein networkhttps://string-db.org/network/1216932.CM240_1341Putative membrane protein.
CDM68501.1 protein networkhttps://string-db.org/network/1216932.CM240_1342Hypothetical protein; Family membership.
CDM68502.1 protein networkhttps://string-db.org/network/1216932.CM240_1343Hypothetical protein; Family membership.
CDM68503.1 protein networkhttps://string-db.org/network/1216932.CM240_1344Type II secretion system protein; The original family covered both the regions found by the current model. The splitting of the family has allowed the related FlaJ_arch (archaeal FlaJ family) to [...]
CDM68504.1 protein networkhttps://string-db.org/network/1216932.CM240_1345Type IV fimbrial assembly protein PilB; This family contains both type II and type IV P54907 pathway secretion proteins from bacteria. P07169 VirB11 ATPase is a subunit of the Agrobacterium tumef [...]
CDM68505.1 protein networkhttps://string-db.org/network/1216932.CM240_1346Putative membrane protein.
galE protein networkhttps://string-db.org/network/1216932.CM240_1347UDP-glucose 4-epimerase; This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions; High confidence in fun [...]
CDM68507.1 protein networkhttps://string-db.org/network/1216932.CM240_1348Putative membrane protein.
CDM68508.1 protein networkhttps://string-db.org/network/1216932.CM240_1349RluA family pseudouridine synthase; Members of this family are involved in modifying bases in RNA molecules. They carry out the conversion of uracil bases to pseudouridine. This family includes R [...]
CDM68509.1 protein networkhttps://string-db.org/network/1216932.CM240_1350Amidohydrolase; This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification [1]. Family M20 are Glutamate carboxypeptidases. Peptidase fam [...]
CDM68510.1 protein networkhttps://string-db.org/network/1216932.CM240_1351FtsA is essential for bacterial cell division, and co-localizes to the septal ring with FtsZ. It has been suggested that the interaction of FtsA-FtsZ has arisen through coevolution in different b [...]
CDM68511.1 protein networkhttps://string-db.org/network/1216932.CM240_1352Superfamily I DNA helicase (rep-like helicase); The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyse ATP dependent unwinding [...]
CDM68512.1 protein networkhttps://string-db.org/network/1216932.CM240_1353Hypothetical protein; Family membership.
thiI protein networkhttps://string-db.org/network/1216932.CM240_1354Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also cataly [...]
CDM68514.1 protein networkhttps://string-db.org/network/1216932.CM240_1355Cysteine desulfurase; A pyridoxal-phosphate protein. The sulfur from free L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors. [...]
CDM68515.1 protein networkhttps://string-db.org/network/1216932.CM240_1356Putative membrane protein; High confidence in function and specificity.
CDM68516.1 protein networkhttps://string-db.org/network/1216932.CM240_1357Hypothetical protein; Family membership.
CDM68517.1 protein networkhttps://string-db.org/network/1216932.CM240_1358Hypothetical protein; Family membership.
cysK3 protein networkhttps://string-db.org/network/1216932.CM240_1359O-acetylserine sulfhydrylase; Cysteine synthase (CSase) is the pyridoxal-phosphate dependent enzyme responsible [1] for the formation of cysteine from O-acetyl-serine and hydrogen sulfide with th [...]
CDM68519.1 protein networkhttps://string-db.org/network/1216932.CM240_1360This family of proteins belongs to the PP-loop superfamily; High confidence in function and specificity.
CDM68520.1 protein networkhttps://string-db.org/network/1216932.CM240_1361Cysteine desulfurase; A pyridoxal-phosphate protein. The sulfur from free L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors. [...]
yfmR protein networkhttps://string-db.org/network/1216932.CM240_1362ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDM68522.1 protein networkhttps://string-db.org/network/1216932.CM240_1363Hypothetical protein; Family membership; Belongs to the peptidase S24 family.
CDM68523.1 protein networkhttps://string-db.org/network/1216932.CM240_1364Putative membrane protein.
CDM68524.1 protein networkhttps://string-db.org/network/1216932.CM240_1365Hypothetical protein; Family membership.
CDM68525.1 protein networkhttps://string-db.org/network/1216932.CM240_1366Hypothetical protein.
CDM68526.1 protein networkhttps://string-db.org/network/1216932.CM240_1367Hypothetical protein; High confidence in function and specificity.
serA protein networkhttps://string-db.org/network/1216932.CM240_13683-phosphoglycerate dehydrogenase, a bacterial enzyme that catalyzes the oxidation of D-3-phosphoglycerate to 3-phosphohydroxypyruvate. This reaction is the first committed step in the 'phosphoryl [...]
CDM68528.1 protein networkhttps://string-db.org/network/1216932.CM240_1369Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes,such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the bas [...]
ycbJ protein networkhttps://string-db.org/network/1216932.CM240_1370Macrolide 2'-phosphotransferase; This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include: aminoglycoside 3'-phosphotransf [...]
CDM68530.1 protein networkhttps://string-db.org/network/1216932.CM240_1371Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; High confidence in function and specificity.
CDM68531.1 protein networkhttps://string-db.org/network/1216932.CM240_1372Hypothetical protein; High confidence in function and specificity.
CDM68532.1 protein networkhttps://string-db.org/network/1216932.CM240_1373The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domai [...]
CDM68533.1 protein networkhttps://string-db.org/network/1216932.CM240_1374Recombinase; This domain is usually found associated with pfam00239 in putative integrases/recombinases of mobile genetic elements of diverse bacteria and phages; High confidence in function and [...]
CDM68534.1 protein networkhttps://string-db.org/network/1216932.CM240_1375Resolvase, N-terminal domain; This domain is usually found associated with PF00239 in putative integrases/recombinases of mobile genetic elements of diverse bacteria and phages; High confidence i [...]
CDM68535.1 protein networkhttps://string-db.org/network/1216932.CM240_1376N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; Proteins families containing this domain include zinc amidases that have N-acetylmuramoyl-L-alanine amidase activityThis enzym [...]
CDM68536.1 protein networkhttps://string-db.org/network/1216932.CM240_1377Toxin secretion/phage lysis holin; Phage holins and lytic enzymes are both necessary for bacterial lysis and virus dissemination.This family also includes TcdE/UtxA involved in toxin secretion in [...]
CDM68537.1 protein networkhttps://string-db.org/network/1216932.CM240_1378O-Glycosyl hydrolases (EC) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A class [...]
CDM68538.1 protein networkhttps://string-db.org/network/1216932.CM240_1379Hypothetical protein; High confidence in function and specificity.
CDM68539.1 protein networkhttps://string-db.org/network/1216932.CM240_1380This family is of prophage tail proteins that are probably acting as endopeptidases; High confidence in function and specificity.
CDM68540.1 protein networkhttps://string-db.org/network/1216932.CM240_1381Phage tail component; This family consists of several Siphovirus and other phage tail component proteins as well as some bacterial proteins of unknown function; High confidence in function and sp [...]
CDM68541.1 protein networkhttps://string-db.org/network/1216932.CM240_1382Hypothetical protein; High confidence in function and specificity.
CDM68542.1 protein networkhttps://string-db.org/network/1216932.CM240_1383Hypothetical protein; High confidence in function and specificity.
CDM68543.1 protein networkhttps://string-db.org/network/1216932.CM240_1384Phage major tail protein, phi13 family; This is a set of proteins that share low levels of sequence similarity but similar lengths and similar patterns of charged, hydrophobic, and Gly/Pro residu [...]
CDM68544.1 protein networkhttps://string-db.org/network/1216932.CM240_1385Hypothetical protein; High confidence in function and specificity.
CDM68545.1 protein networkhttps://string-db.org/network/1216932.CM240_1386Phage protein, HK97 gp10 family; This family of proteins is found in the caudovirales. It may be a tail component; High confidence in function and specificity.
CDM68546.1 protein networkhttps://string-db.org/network/1216932.CM240_1387This entry describes the head-tail adaptor protein of bacteriophage SPP1 and related proteins in other bacteriophage and prophage regions of bacterial genomes. Homologues are also found in Gene T [...]
CDM68547.1 protein networkhttps://string-db.org/network/1216932.CM240_1388Hypothetical protein.
CDM68548.1 protein networkhttps://string-db.org/network/1216932.CM240_1389Family of bacteriophage hypothetical proteins and capsid proteins; High confidence in function and specificity.
CDM68549.1 protein networkhttps://string-db.org/network/1216932.CM240_1390Peptidase S14 ClpP; The Clp protease has an active site catalytic triad. In E. coli Clp protease, ser-111, his-136 and asp-185 form the catalytic triad. P48254 has lost all of these active site r [...]
CDM68550.1 protein networkhttps://string-db.org/network/1216932.CM240_1391Phage portal protein, HK97 family; Bacteriophage portal proteins form a dodecamer and is located at a five-fold vertex of the viral capsid. The portal complex forms a channel through which the vi [...]
CDM68551.1 protein networkhttps://string-db.org/network/1216932.CM240_1392Terminase; The majority of the members of this family are bacteriophage proteins, several of which are thought to be terminase large subunit proteins. There are also a number of bacterial protein [...]
CDM68552.1 protein networkhttps://string-db.org/network/1216932.CM240_1393Hypothetical protein.
CDM68553.1 protein networkhttps://string-db.org/network/1216932.CM240_1394Hypothetical protein; High confidence in function and specificity.
CDM68554.1 protein networkhttps://string-db.org/network/1216932.CM240_1395Hypothetical protein; High confidence in function and specificity.
CDM68555.1 protein networkhttps://string-db.org/network/1216932.CM240_1396Hypothetical protein.
CDM68556.1 protein networkhttps://string-db.org/network/1216932.CM240_1397Hypothetical protein; High confidence in function and specificity.
CDM68557.1 protein networkhttps://string-db.org/network/1216932.CM240_1398DNA-cytosine methyltransferase; C-5 cytosine-specific DNA methylases (EC) (C5 Mtase) are enzymes that specifically methylate the C-5 carbon of cytosines in DNA to produce C5-methylcytosine. In ma [...]
CDM68558.1 protein networkhttps://string-db.org/network/1216932.CM240_1399DNA methylase N-4/N-6 domain-containing protein; N-6 adenine-specific DNA methylases (A-Mtase) are enzymes that specifically methylate the amino group at the C-6 position of adenines in DNA. Such [...]
metK3 protein networkhttps://string-db.org/network/1216932.CM240_1400Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate h [...]
CDM68560.1 protein networkhttps://string-db.org/network/1216932.CM240_1401Hypothetical protein; High confidence in function and specificity.
CDM68561.1 protein networkhttps://string-db.org/network/1216932.CM240_1402HNH endonuclease is found in bacteria and viruses. This family includes pyocins, colicins and anaredoxins; High confidence in function and specificity.
CDM68562.1 protein networkhttps://string-db.org/network/1216932.CM240_1403Hypothetical protein; High confidence in function and specificity.
CDM68563.1 protein networkhttps://string-db.org/network/1216932.CM240_1404Hypothetical protein.
CDM68564.1 protein networkhttps://string-db.org/network/1216932.CM240_1405Phage-associated helicase, snf2 family; This domain is found in proteins involved in a variety of processes including transcription regulation (e.g, SNF2, STH1, brahma, MOT1), DNA repair (e.g,ERC [...]
CDM68565.1 protein networkhttps://string-db.org/network/1216932.CM240_1406Hypothetical protein; High confidence in function and specificity.
CDM68566.1 protein networkhttps://string-db.org/network/1216932.CM240_1407Hypothetical protein; This family contains several bacterial virulence-associated protein E like proteins. These proteins contain a P-loop motif; High confidence in function and specificity.
CDM68567.1 protein networkhttps://string-db.org/network/1216932.CM240_1408Hypothetical protein; High confidence in function and specificity.
CDM68568.1 protein networkhttps://string-db.org/network/1216932.CM240_1409Phage antirepressor protein; This domain was called the KilAC domain by Iyer and colleagues; High confidence in function and specificity.
CDM68569.1 protein networkhttps://string-db.org/network/1216932.CM240_1410Putative membrane protein.
CDM68570.1 protein networkhttps://string-db.org/network/1216932.CM240_1411Putative membrane protein; High confidence in function and specificity.
CDM68571.1 protein networkhttps://string-db.org/network/1216932.CM240_1412TetR family transcriptional regulator; This entry represents a DNA-binding domain with a helix-turn-helix (HTH) structure that is found in several bacterial and archaeal transcriptional regulator [...]
L5 protein networkhttps://string-db.org/network/1216932.CM240_1413DNA-directed DNA polymerases are the key enzymes catalysing the accurate replication of DNA. They require either a small RNA molecule or a protein as a primer for the de novo synthesis of a DNA c [...]
CDM68573.1 protein networkhttps://string-db.org/network/1216932.CM240_1414Hypothetical protein; High confidence in function and specificity.
CDM68574.1 protein networkhttps://string-db.org/network/1216932.CM240_1415Hypothetical protein; High confidence in function and specificity.
CDM68575.1 protein networkhttps://string-db.org/network/1216932.CM240_1416Hypothetical protein; High confidence in function and specificity.
CDM68576.1 protein networkhttps://string-db.org/network/1216932.CM240_1417Hypothetical protein; High confidence in function and specificity.
CDM68577.1 protein networkhttps://string-db.org/network/1216932.CM240_1418Hypothetical protein; High confidence in function and specificity.
CDM68578.1 protein networkhttps://string-db.org/network/1216932.CM240_1419Restriction endonuclease; This family includes the NgoFVII (recognises GCSGC but cleavage site unknown) restriction endonuclease; High confidence in function and specificity.
CDM68579.1 protein networkhttps://string-db.org/network/1216932.CM240_1420Hypothetical protein; High confidence in function and specificity.
CDM68580.1 protein networkhttps://string-db.org/network/1216932.CM240_1421Hypothetical protein; High confidence in function and specificity.
bbvIM protein networkhttps://string-db.org/network/1216932.CM240_1422Modification methylase BbvI; High confidence in function and specificity.
CDM68582.1 protein networkhttps://string-db.org/network/1216932.CM240_1423Hypothetical protein; High confidence in function and specificity.
CDM68583.1 protein networkhttps://string-db.org/network/1216932.CM240_1424Putative RNA methyltransferase CTC_01941; This family consists of (Uracil-5-)-methyltransferasesfrom bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conser [...]
CDM68584.1 protein networkhttps://string-db.org/network/1216932.CM240_1425Putative membrane protein; Family membership.
CDM68585.1 protein networkhttps://string-db.org/network/1216932.CM240_1426Putative membrane protein.
CDM68586.1 protein networkhttps://string-db.org/network/1216932.CM240_1427Putative membrane protein.
CDM68587.1 protein networkhttps://string-db.org/network/1216932.CM240_1428Hypothetical protein; Family membership.
CDM68588.1 protein networkhttps://string-db.org/network/1216932.CM240_1429Hypothetical protein.
CDM68589.1 protein networkhttps://string-db.org/network/1216932.CM240_1430Hypothetical protein.
pdp protein networkhttps://string-db.org/network/1216932.CM240_1431Pyrimidine-nucleoside phosphorylase; This domain is found at the C-terminal end of the large alpha/beta domain making up various pyrimidine nucleoside phosphorylases.It has slightly different con [...]
punA1 protein networkhttps://string-db.org/network/1216932.CM240_1432Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the forma [...]
punA3 protein networkhttps://string-db.org/network/1216932.CM240_1433Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the forma [...]
deoB protein networkhttps://string-db.org/network/1216932.CM240_1434Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
CDM68594.1 protein networkhttps://string-db.org/network/1216932.CM240_1435Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chro [...]
CDM68595.1 protein networkhttps://string-db.org/network/1216932.CM240_1436Putative membrane protein.
CDM68596.1 protein networkhttps://string-db.org/network/1216932.CM240_1437The generic name 'NUDIX hydrolases' (NUcleoside DIphosphate linked to some other moiety X) has been coined for this domain family. The family can be divided into a number of subgroups, of which M [...]
ilvB1 protein networkhttps://string-db.org/network/1216932.CM240_1438Acetolactate synthase large subunit; A number of enzymes require thiamine pyrophosphate (TPP) (vitamin B1) as a cofactor. It has been shown that some of these enzymes are structurally related; Hi [...]
leuB protein networkhttps://string-db.org/network/1216932.CM240_14393-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
leuD protein networkhttps://string-db.org/network/1216932.CM240_14403-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. Leu [...]
leuC protein networkhttps://string-db.org/network/1216932.CM240_14413-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
ilvC protein networkhttps://string-db.org/network/1216932.CM240_1442Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
CDM68602.1 protein networkhttps://string-db.org/network/1216932.CM240_1443Acetolactate synthase, small subunit; ALS_ss_C is the C-terminal half of a family of proteins which are the small subunits of acetolactate synthase. Acetolactate synthase is a tetrameric enzyme,c [...]
spo0A protein networkhttps://string-db.org/network/1216932.CM240_1444Stage 0 sporulation protein A homolog; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in res [...]
CDM68604.1 protein networkhttps://string-db.org/network/1216932.CM240_1445The protein SpoIVB is a serine peptidase that plays a central role in a regulatory checkpoint (the sigma-K checkpoint) which coordinates gene expression during the later stages of spore formation [...]
CDM68605.1 protein networkhttps://string-db.org/network/1216932.CM240_1446DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
argR protein networkhttps://string-db.org/network/1216932.CM240_1447Arginine repressor; Regulates arginine biosynthesis genes.
ppnK protein networkhttps://string-db.org/network/1216932.CM240_1448Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically t [...]
yqxC protein networkhttps://string-db.org/network/1216932.CM240_1449Putative rRNA methyltransferase YqxC; This family consists of FtsJ from various bacterial and archaeal sources FtsJ is a methyltransferase, but actually has no effect on cell division. FtsJ's sub [...]
dxs protein networkhttps://string-db.org/network/1216932.CM240_14501-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (D [...]
ispA protein networkhttps://string-db.org/network/1216932.CM240_1451Farnesyl diphosphate synthase; Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)-farnesyl diphosphate; High confidence in function and specificity; Belongs to the FPP/GGPP syn [...]
xseB protein networkhttps://string-db.org/network/1216932.CM240_1452Hypothetical protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs t [...]
xseA protein networkhttps://string-db.org/network/1216932.CM240_1453Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleo [...]
folD protein networkhttps://string-db.org/network/1216932.CM240_1454Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahy [...]
nusB protein networkhttps://string-db.org/network/1216932.CM240_1455Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator seque [...]
CDM68615.1 protein networkhttps://string-db.org/network/1216932.CM240_1456Asp23 family protein; This entry represents the alkaline shock protein 23 family. These small proteins are involved in alkaline pH tolerance of Staphylococcus aureus; Hypothetical protein.
CDM68616.1 protein networkhttps://string-db.org/network/1216932.CM240_1457Stage III sporulation protein AH (SpoIIIAH) is a protein that is involved in forespore engulfment. It forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the [...]
CDM68617.1 protein networkhttps://string-db.org/network/1216932.CM240_1458This entry represents the stage III sporulation protein AG, which is encoded in a spore formation operon: spoIIIAABCDEFGH under the control of sigma G. A comparative genome analysis of all sequen [...]
CDM68618.1 protein networkhttps://string-db.org/network/1216932.CM240_1459This family represents the stage III sporulation protein AF (SpoIIIAF) of the bacterial endospore formation program, which exists in some but not all members of the Firmicutes (formerly called lo [...]
CDM68619.1 protein networkhttps://string-db.org/network/1216932.CM240_1460This represents the stage III sporulation protein AE, which is encoded in a spore formation operon spoIIIAABCDEFGH under the control of sigma G. A comparative genome analysis of all sequenced gen [...]
CDM68620.1 protein networkhttps://string-db.org/network/1216932.CM240_1461This family consists of several bacterial stage III sporulation protein AC (SpoIIIAC) and SpoIIIAD sequences. The exact function of this family is unknown. SpoIIIAD is an uncharacterised protein [...]
CDM68621.1 protein networkhttps://string-db.org/network/1216932.CM240_1462Putative membrane protein.
CDM68622.1 protein networkhttps://string-db.org/network/1216932.CM240_1463SpoIIIAB represents the stage III sporulation protein AB, which is encoded in a spore formation operon: spoIIIAABCDEFGH that is under sigma G regulation [1]. A comparative genome analysis of all [...]
spoIIIAA protein networkhttps://string-db.org/network/1216932.CM240_1464Proteins in this entry include the stage III sporulation protein AA that is encoded by one of several genes in the spoIIIA locus. This protein is only found in species that are capable of endospo [...]
CDM68624.1 protein networkhttps://string-db.org/network/1216932.CM240_1465Hypothetical protein; Family membership.
recO protein networkhttps://string-db.org/network/1216932.CM240_1466DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
era protein networkhttps://string-db.org/network/1216932.CM240_1467GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cyc [...]
cdd protein networkhttps://string-db.org/network/1216932.CM240_1468Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
CDM68628.1 protein networkhttps://string-db.org/network/1216932.CM240_1469Diacylglycerol kinase/PAP2 family protein; In bacteria, dialcylglycerol kinase is very small (13 to 15 kD) membrane protein which seems to contain three transmembrane domains. The best conserved [...]
ybeY protein networkhttps://string-db.org/network/1216932.CM240_1470Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
CDM68630.1 protein networkhttps://string-db.org/network/1216932.CM240_1471Putative hydrolase; The HD domain is found in a superfamily of enzymes with a predicted or known phosphohydrolase activity. These enzymes appear to be involved in the nucleic acid metabolism, sig [...]
CDM68631.1 protein networkhttps://string-db.org/network/1216932.CM240_1472This family consists of several putative bacterial stage IV sporulation (SpoIV) proteins. YqfD of Bacillus subtilis (P54469) is known to be essential for efficient sporulation although its exact [...]
CDM68632.1 protein networkhttps://string-db.org/network/1216932.CM240_1473Hypothetical protein; Family membership.
rpsU protein networkhttps://string-db.org/network/1216932.CM240_1474Ribosomal protein S21 is one of the proteins from the small ribosomal subunit. So far S21 has only been found in eubacteria. It is a protein of 55 to 70 amino-acid residues; Hypothetical protein.
CDM68634.1 protein networkhttps://string-db.org/network/1216932.CM240_1475HIT family hydrolase; The Histidine Triad (HIT) motif,His-x-His-x-His-x-x (x, a hydrophobic amino acid) was identified as being highly conserved in a variety of organisms. Crystal structure of ra [...]
mtaB protein networkhttps://string-db.org/network/1216932.CM240_1476Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB; Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t6A), leading to the formation of 2-methylthio-N6-threonylcarbamoylade [...]
2.1.1.193 protein networkhttps://string-db.org/network/1216932.CM240_1477Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subuni [...]
prmA3 protein networkhttps://string-db.org/network/1216932.CM240_1478Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
dnaJ protein networkhttps://string-db.org/network/1216932.CM240_1479Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an [...]
dnaK3 protein networkhttps://string-db.org/network/1216932.CM240_1480Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
grpE protein networkhttps://string-db.org/network/1216932.CM240_1481Putative heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and Grp [...]
hrcA protein networkhttps://string-db.org/network/1216932.CM240_1482Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
hemN protein networkhttps://string-db.org/network/1216932.CM240_1483Oxygen-independent coproporphyrinogen-III oxidase 1; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Bind [...]
lepA protein networkhttps://string-db.org/network/1216932.CM240_1484Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon bac [...]
CDM68644.1 protein networkhttps://string-db.org/network/1216932.CM240_1485This family contains the bacterial stage II sporulation protein P (SpoIIP) (approximately 350 residues long). It has been shown that a block in polar cytokinesis in Bacillus subtilis is mediated [...]
gpr protein networkhttps://string-db.org/network/1216932.CM240_1486Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
rpsT protein networkhttps://string-db.org/network/1216932.CM240_148730S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
CDM68647.1 protein networkhttps://string-db.org/network/1216932.CM240_1488DNA polymerase III, delta subunit is required for,along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalysed reactio [...]
CDM68648.1 protein networkhttps://string-db.org/network/1216932.CM240_1489Putative membrane protein.
CDM68649.1 protein networkhttps://string-db.org/network/1216932.CM240_1490Hypothetical protein; Family membership.
CDM68650.1 protein networkhttps://string-db.org/network/1216932.CM240_1491Putative comE operon protein 1; The soluble ligand-binding beta-grasp domain (SLBB) contains a beta-grasp fold. They are found in a diverse set of proteins that include the animal vitamin B12 upt [...]
CDM68651.1 protein networkhttps://string-db.org/network/1216932.CM240_1492RluA family pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
CDM68652.1 protein networkhttps://string-db.org/network/1216932.CM240_1493Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation [2]. This protein may also be involved [...]
CDM68653.1 protein networkhttps://string-db.org/network/1216932.CM240_1494Putative membrane protein.
nadD protein networkhttps://string-db.org/network/1216932.CM240_1495Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
CDM68655.1 protein networkhttps://string-db.org/network/1216932.CM240_1496Hypothetical protein; Family membership.
obg protein networkhttps://string-db.org/network/1216932.CM240_1497GTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in contro [...]
rpmA protein networkhttps://string-db.org/network/1216932.CM240_1498L27 is a protein from the large (50S) subunit; it is essential for ribosome function, but its exact role is unclear. It belongs to a family of ribosomal proteins,examples of which are found in ba [...]
CDM68658.1 protein networkhttps://string-db.org/network/1216932.CM240_1499Hypothetical protein.
rplU protein networkhttps://string-db.org/network/1216932.CM240_150050S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
CDM68660.1 protein networkhttps://string-db.org/network/1216932.CM240_1501Ribonuclease, Rne/Rng family; Ribonuclease E and Ribonuclease G are related enzymes that cleave a wide variety of RNAs; High confidence in function and specificity.
CDM68661.1 protein networkhttps://string-db.org/network/1216932.CM240_1502Hypothetical protein; High confidence in function and specificity.
CDM68662.1 protein networkhttps://string-db.org/network/1216932.CM240_1503Radical SAM protein; High confidence in function and specificity.
CDM68663.1 protein networkhttps://string-db.org/network/1216932.CM240_1504Putative membrane protein; High confidence in function and specificity.
rodA-2 protein networkhttps://string-db.org/network/1216932.CM240_1505Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
minE protein networkhttps://string-db.org/network/1216932.CM240_1506Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures c [...]
minD protein networkhttps://string-db.org/network/1216932.CM240_1507Septum site-determining protein MinD; ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blockin [...]
minC protein networkhttps://string-db.org/network/1216932.CM240_1508Putative septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ fila [...]
CDM68668.1 protein networkhttps://string-db.org/network/1216932.CM240_1509Penicillin-binding protein; This domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. Its function has not been precisely defined, but is strongly impli [...]
CDM68669.1 protein networkhttps://string-db.org/network/1216932.CM240_1510Putative membrane protein.
CDM68670.1 protein networkhttps://string-db.org/network/1216932.CM240_1511Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape.
mreB protein networkhttps://string-db.org/network/1216932.CM240_1512This family consists of bacterial MreB and Mbl proteins as well as two related archaeal sequences. MreB is known to be a rod shape-determining protein in bacteria and goes to make up the bacteria [...]
CDM68672.1 protein networkhttps://string-db.org/network/1216932.CM240_1513A family of proteins present widely across the bacteria. This family was named initially with reference to the E. coli radC102 mutation which suggested that RadC was involved in repair of DNA les [...]
maf protein networkhttps://string-db.org/network/1216932.CM240_1514Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides in [...]
CDM68674.1 protein networkhttps://string-db.org/network/1216932.CM240_1515Putative membrane protein.
CDM68675.1 protein networkhttps://string-db.org/network/1216932.CM240_1516Hypothetical protein; Family membership.
CDM68676.1 protein networkhttps://string-db.org/network/1216932.CM240_1517Hypothetical protein.
CDM68677.1 protein networkhttps://string-db.org/network/1216932.CM240_1518Hypothetical protein; High confidence in function and specificity; Belongs to the UPF0735 family.
CDM68678.1 protein networkhttps://string-db.org/network/1216932.CM240_1519Cytidine deaminase (EC) (cytidine aminohydrolase) catalyzes the hydrolysis of cytidine into uridine and ammonia while deoxycytidylate deaminase (EC) (dCMP deaminase) hydrolyzes dCMP into dUMP. Bo [...]
CDM68679.1 protein networkhttps://string-db.org/network/1216932.CM240_1520Hypothetical protein; Family membership.
CDM68680.1 protein networkhttps://string-db.org/network/1216932.CM240_1521Putative exonuclease; This protein belongs to IPR013520.This entry includes a variety of exonuclease proteins, such as ribonuclease T [PUBMED:8506149] and the epsilon subunit of DNA polymerase II [...]
CDM68681.1 protein networkhttps://string-db.org/network/1216932.CM240_1522Putative membrane protein.
CDM68682.1 protein networkhttps://string-db.org/network/1216932.CM240_1523Putative secreted protein.
CDM68683.1 protein networkhttps://string-db.org/network/1216932.CM240_1525Transglycosylase; This family is distantly related to PF00062. Members are found in phages, type II, type III and type IV secretion systems; High confidence in function and specificity.
coaE protein networkhttps://string-db.org/network/1216932.CM240_1526dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
polA protein networkhttps://string-db.org/network/1216932.CM240_1527DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
CDM68686.1 protein networkhttps://string-db.org/network/1216932.CM240_1528Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
CDM68687.1 protein networkhttps://string-db.org/network/1216932.CM240_1529Hypothetical protein; Family membership.
CDM68688.1 protein networkhttps://string-db.org/network/1216932.CM240_1530Appr-1-p processing domain protein; The Macro or A1pp domain is a module of about 180 amino acids which can bind ADP-ribose, an NAD metabolite or related ligands. Binding to ADP-ribose could be e [...]
CDM68689.1 protein networkhttps://string-db.org/network/1216932.CM240_1531Hypothetical protein.
CDM68690.1 protein networkhttps://string-db.org/network/1216932.CM240_1532ArsC family protein; Several bacterial taxon have a chromosomal resistance system, encoded by the ars operon, for the detoxification of arsenate, arsenite, and antimonite.This system transports a [...]
CDM68691.1 protein networkhttps://string-db.org/network/1216932.CM240_1533Aspartokinase (AK) [1] catalyzes the phosphorylation of aspartate. The product of this reaction can then be used in the biosynthesis of lysine or in the pathway leading to homoserine, which parti [...]
kat protein networkhttps://string-db.org/network/1216932.CM240_1534Catalase or more correctly, hydroperoxidase is a heme-containing enzyme, present in all aerobic cells,that decomposes hydrogen peroxide to molecular oxygen and water. Its main function is to prot [...]
CDM68693.1 protein networkhttps://string-db.org/network/1216932.CM240_1535D-alanyl-D-alanine carboxypeptidase; Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Required specifically for the synthesis of the spore form of peptidoglycan (cort [...]
CDM68694.1 protein networkhttps://string-db.org/network/1216932.CM240_1536Hypothetical protein; Family membership.
CDM68695.1 protein networkhttps://string-db.org/network/1216932.CM240_1537Sporulation protein YtfJ; Members of this protein family, exemplified by YtfJ of Bacillus subtilis, are encoded by bacterial genomes if and only if the species is capable of endospore formation. [...]
scpB protein networkhttps://string-db.org/network/1216932.CM240_1538Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA awa [...]
scpA protein networkhttps://string-db.org/network/1216932.CM240_1539Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA awa [...]
CDM68698.1 protein networkhttps://string-db.org/network/1216932.CM240_1540Serine-type D-Ala-D-Ala carboxypeptidase; '; High confidence in function and specificity; Belongs to the peptidase S11 family.
CDM68699.1 protein networkhttps://string-db.org/network/1216932.CM240_1541The flagellar motor switch in Escherichia coli and Salmonella typhimurium regulates the direction of flagellar rotation and hence controls swimming behaviour. The switch is a complex apparatus th [...]
CDM68700.1 protein networkhttps://string-db.org/network/1216932.CM240_1542Flagellar motor switch protein FliM; One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins [...]
CDM68701.1 protein networkhttps://string-db.org/network/1216932.CM240_1543Putative chemotaxis protein; The CheW-like domain is an around 150-residue domain that is found in proteins involved in the two-component signaling systems regulating bacterial chemotaxis. Two co [...]
CDM68702.1 protein networkhttps://string-db.org/network/1216932.CM240_1544Chemotaxis protein CheY; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY seems to regulate the clockwise (CW) rotation; High confidence in fu [...]
CDM68703.1 protein networkhttps://string-db.org/network/1216932.CM240_1545CheC, inhibitor of MCP methylation; The restoration of pre-stimulus levels of the chemotactic response regulator, CheY-P, is important for allowing bacteria to respond to new environmental stimul [...]
cheA protein networkhttps://string-db.org/network/1216932.CM240_1546Chemotaxis protein CheA; High confidence in function and specificity.
cheR protein networkhttps://string-db.org/network/1216932.CM240_1547CheR proteins are part of the chemotaxis signaling mechanism in bacteria. CheR methylates the chemotaxis receptor at specific glutamate residues. CheR is an S-adenosylmethionine-dependent methylt [...]
cheB protein networkhttps://string-db.org/network/1216932.CM240_1548Chemotaxis response regulator protein-glutamate methylesterase; Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced in [...]
cheD protein networkhttps://string-db.org/network/1216932.CM240_1549Putative chemoreceptor glutamine deamidase CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belo [...]
CDM68708.1 protein networkhttps://string-db.org/network/1216932.CM240_1550CheW proteins are part of the chemotaxis signaling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller r [...]
CDM68709.1 protein networkhttps://string-db.org/network/1216932.CM240_1551Hypothetical protein; Family membership.
ldh1 protein networkhttps://string-db.org/network/1216932.CM240_1552L-lactate dehydrogenase 1; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
CDM68711.1 protein networkhttps://string-db.org/network/1216932.CM240_1553Branched-chain amino-acid aminotransferase (transaminase B), a bacterial (gene ilvE) and eukaryotic enzyme which catalyzes the reversible transfer of an amino group from 4-methyl-2-oxopentanoate [...]
CDM68712.1 protein networkhttps://string-db.org/network/1216932.CM240_1554Hypothetical protein.
nifJ protein networkhttps://string-db.org/network/1216932.CM240_1555Pyruvate-flavodoxin oxidoreductase; High confidence in function and specificity.
murG protein networkhttps://string-db.org/network/1216932.CM240_1556Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
CDM68715.1 protein networkhttps://string-db.org/network/1216932.CM240_1557Hypothetical protein; Family membership.
CDM68716.1 protein networkhttps://string-db.org/network/1216932.CM240_1558single-stranded-DNA-specific exonuclease RecJ; It is predicted that this family of proteins all perform a phosphoesterase function. It included the single stranded DNA exonuclease RecJ; High conf [...]
CDM68717.1 protein networkhttps://string-db.org/network/1216932.CM240_1559Cadmium-translocating P-type ATPase; Couples the hydrolysis of ATP with the transport of cadmium, zinc and cobalt out of the cell. Does not seem to transport copper; High confidence in function a [...]
CDM68718.1 protein networkhttps://string-db.org/network/1216932.CM240_1560Zinc protease; These domains share the same active site motif of HxxEH located in the first core helix, but differ in one of the metal-binding residues. LuxS, the AI-2 (autoinducer-2) producing e [...]
CDM68719.1 protein networkhttps://string-db.org/network/1216932.CM240_1561DJ-1 family protein; The family includes the protease PfpI Q51732. This domain is also found in transcriptional regulators such as Q9RJG8. This N-terminal region of the full-length AdpA proteins [...]
CDM68720.1 protein networkhttps://string-db.org/network/1216932.CM240_1562Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; High confidence [...]
gyrB3 protein networkhttps://string-db.org/network/1216932.CM240_1563DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, i [...]
CDM68722.1 protein networkhttps://string-db.org/network/1216932.CM240_1564Hypothetical protein; Family membership.
CDM68723.1 protein networkhttps://string-db.org/network/1216932.CM240_1565Hypothetical protein; Family membership.
CDM68724.1 protein networkhttps://string-db.org/network/1216932.CM240_1566Putative GTP cyclohydrolase 1 type 2; Converts GTP to dihydroneopterin triphosphate; High confidence in function and specificity.
CDM68725.1 protein networkhttps://string-db.org/network/1216932.CM240_1567This family of proteins are uncharacterised have no known function; High confidence in function and specificity.
CDM68726.1 protein networkhttps://string-db.org/network/1216932.CM240_1568Putative membrane protein.
rpoD protein networkhttps://string-db.org/network/1216932.CM240_1569RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the p [...]
dnaG protein networkhttps://string-db.org/network/1216932.CM240_1570DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
CDM68729.1 protein networkhttps://string-db.org/network/1216932.CM240_1571Deoxyguanosinetriphosphate triphosphohydrolase-like protein; dGTP triphosphohydrolase (dgt) releases inorganic triphosphate, an unusual activity reaction product, from GTP. Its activity has been [...]
CDM68730.1 protein networkhttps://string-db.org/network/1216932.CM240_1572Hypothetical protein; High confidence in function and specificity.
ppdK protein networkhttps://string-db.org/network/1216932.CM240_1573Pyruvate, phosphate dikinase; High confidence in function and specificity; Belongs to the PEP-utilizing enzyme family.
CDM68732.1 protein networkhttps://string-db.org/network/1216932.CM240_1574CBS domain protein; CBS (cystathionine-beta-synthase) domains are small intracellular modules, mostly found in two or four copies within a protein, that occur in a variety of proteins in bacteria [...]
CDM68733.1 protein networkhttps://string-db.org/network/1216932.CM240_1575Hypothetical protein; Family membership.
efp protein networkhttps://string-db.org/network/1216932.CM240_1576Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirect [...]
CDM68735.1 protein networkhttps://string-db.org/network/1216932.CM240_1577Putative membrane protein.
CDM68736.1 protein networkhttps://string-db.org/network/1216932.CM240_1578Hypothetical protein; Family membership.
CDM68737.1 protein networkhttps://string-db.org/network/1216932.CM240_1579Hypothetical protein; Family membership.
CDM68738.1 protein networkhttps://string-db.org/network/1216932.CM240_1580Putative membrane protein.
CDM68739.1 protein networkhttps://string-db.org/network/1216932.CM240_1581Hypothetical protein; Family membership.
CDM68740.1 protein networkhttps://string-db.org/network/1216932.CM240_1582Hypothetical protein; Family membership.
CDM68741.1 protein networkhttps://string-db.org/network/1216932.CM240_1583Type II secretion system protein E; A number of bacterial proteins, some of which are involved in a general secretion pathway (GSP) for the export of proteins (also called the type II pathway),ha [...]
CDM68742.1 protein networkhttps://string-db.org/network/1216932.CM240_1584Hypothetical protein; Family membership.
CDM68743.1 protein networkhttps://string-db.org/network/1216932.CM240_1585Fibronectin-binding protein; This family consists of the N-terminal region of the prokaryotic fibronectin-binding protein. Fibronectin binding is considered to be an important virulence factor in [...]
CDM68744.1 protein networkhttps://string-db.org/network/1216932.CM240_1586Hypothetical protein; High confidence in function and specificity.
dinB protein networkhttps://string-db.org/network/1216932.CM240_1587DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misa [...]
CDM68746.1 protein networkhttps://string-db.org/network/1216932.CM240_1588Putative membrane protein.
CDM68747.1 protein networkhttps://string-db.org/network/1216932.CM240_1589Stage V sporulation protein AF; Dormant Bacillus subtilis spores germinate in the presence of particular nutrients called germinants. The spores are thought to recognise germinants through recept [...]
pyrP protein networkhttps://string-db.org/network/1216932.CM240_1590Uric acid permeases which promotes uptake of uric acid into the cell in limiting-nitrogen conditions; High confidence in function and specificity.
pyrR protein networkhttps://string-db.org/network/1216932.CM240_1591Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase fami [...]
ylyB protein networkhttps://string-db.org/network/1216932.CM240_1592Putative RNA pseudouridine synthase YlyB; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
lspA protein networkhttps://string-db.org/network/1216932.CM240_1593Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
CDM68752.1 protein networkhttps://string-db.org/network/1216932.CM240_1594Putative RNA polymerase-binding protein DksA; Family membership.
CDM68753.1 protein networkhttps://string-db.org/network/1216932.CM240_1595MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thio [...]
CDM68754.1 protein networkhttps://string-db.org/network/1216932.CM240_1596Putative septum site-determining protein divIVA; The Bacillus subtilis divIVA1 mutation causes misplacement of the septum during cell division,resulting in the formation of small, circular, anucl [...]
CDM68755.1 protein networkhttps://string-db.org/network/1216932.CM240_1597Hypothetical protein; High confidence in function and specificity.
sepF protein networkhttps://string-db.org/network/1216932.CM240_1598Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of F [...]
CDM68757.1 protein networkhttps://string-db.org/network/1216932.CM240_1599Proline synthetase associated protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
CDM68758.1 protein networkhttps://string-db.org/network/1216932.CM240_1600Hypothetical protein; Family membership.
CDM68759.1 protein networkhttps://string-db.org/network/1216932.CM240_1601Putative membrane protein.
CDM68760.1 protein networkhttps://string-db.org/network/1216932.CM240_1602Hypothetical protein; High confidence in function and specificity.
CDM68761.1 protein networkhttps://string-db.org/network/1216932.CM240_1603Cell division protein DivIB; Essential cell division protein.
CDM68762.1 protein networkhttps://string-db.org/network/1216932.CM240_1604Cell cycle protein, FtsW/RodA/SpoVE family; A number of prokaryotic integral membrane proteins involved in cell cycle processes have been found to be structurally related. These proteins include, [...]
mraY protein networkhttps://string-db.org/network/1216932.CM240_1605Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...]
murF protein networkhttps://string-db.org/network/1216932.CM240_1606UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptid [...]
murE protein networkhttps://string-db.org/network/1216932.CM240_1607UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UM [...]
CDM68766.1 protein networkhttps://string-db.org/network/1216932.CM240_1608Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation i [...]
CDM68767.1 protein networkhttps://string-db.org/network/1216932.CM240_1609Putative membrane protein.
rsmH protein networkhttps://string-db.org/network/1216932.CM240_1610Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
mraZ protein networkhttps://string-db.org/network/1216932.CM240_1611Protein MraZ; This small 70 amino acid domain is found duplicated in a family of bacterial proteins. These proteins may be DNA-binding transcription factors; High confidence in function and speci [...]
engD protein networkhttps://string-db.org/network/1216932.CM240_1612GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
CDM68771.1 protein networkhttps://string-db.org/network/1216932.CM240_1613ATP-dependent protease La; The Lon serine proteases must hydrolyse ATP to degrade protein substrates. In Escherichia coli, these proteases are involved in turnover of intracellular proteins, incl [...]
deoC protein networkhttps://string-db.org/network/1216932.CM240_1614Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB ald [...]
CDM68773.1 protein networkhttps://string-db.org/network/1216932.CM240_1615Hypothetical protein.
CDM68774.1 protein networkhttps://string-db.org/network/1216932.CM240_1616Calcium-translocating P-type ATPase, PMCA-type; Members of this families are involved in Na+/K+,H+/K+, Ca++ and Mg++ transport. This family represents 5 transmembrane helices; High confidence in [...]
CDM68775.1 protein networkhttps://string-db.org/network/1216932.CM240_1617Manganese-dependent inorganic pyrophosphatase; CBS domains contain about 60 amino acid residues and occur as tandem pairs in a variety of proteins in bacteria,archaea, and eukaryotes. They are ma [...]
CDM68776.1 protein networkhttps://string-db.org/network/1216932.CM240_1618Putative chemotaxis protein MotB; This is the MotB member of the E.coli MotA/MotB proton-channel complex that forms the stator of the bacterial membrane flagellar motor. Key residues act as a plu [...]
motA protein networkhttps://string-db.org/network/1216932.CM240_1619Hypothetical protein; This family groups together integral membrane proteins that appear to be involved translocation of proteins across a membrane. These proteins are probably proton channels. M [...]
CDM68778.1 protein networkhttps://string-db.org/network/1216932.CM240_1620Fagellar hook-basal body protein; Many bacterial species swim actively by means of flagella. The flagella organelle is made of three parts: the basal body, the hook and the filament. The basal bo [...]
flgG protein networkhttps://string-db.org/network/1216932.CM240_1621Flagellar basal body rod protein FlgG; Many bacterial species swim actively by means of flagella. The flagella organelle is made of three parts: the basal body, the hook and the filament. The bas [...]
CDM68780.1 protein networkhttps://string-db.org/network/1216932.CM240_1622Hypothetical protein.
CDM68781.1 protein networkhttps://string-db.org/network/1216932.CM240_1623Hypothetical protein; Family membership.
CDM68782.1 protein networkhttps://string-db.org/network/1216932.CM240_1624Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; High confidence in function and specificity.
CDM68783.1 protein networkhttps://string-db.org/network/1216932.CM240_1625Putative Flagellar protein; Family membership.
CDM68784.1 protein networkhttps://string-db.org/network/1216932.CM240_1626MinD family ATPase; This domain is found in various cobyrinic acid a,c-diamide synthases. These include CbiA and CbiP from S. typhimurium, and CobQ from R. capsulatus. These amidases catalyse ami [...]
CDM68785.1 protein networkhttps://string-db.org/network/1216932.CM240_1627Flagellar biosynthesis protein FlhF; This family includes relatives of the G-domain of the SRP54 family of proteins; Family membership.
flhA protein networkhttps://string-db.org/network/1216932.CM240_1628Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs [...]
CDM68787.1 protein networkhttps://string-db.org/network/1216932.CM240_1629Flagellar biosynthetic protein FlhB; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.
fliQ protein networkhttps://string-db.org/network/1216932.CM240_1630Putative Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.
fliP protein networkhttps://string-db.org/network/1216932.CM240_1631Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
CDM68790.1 protein networkhttps://string-db.org/network/1216932.CM240_1632Flagellar biosynthesis domain protein; FliO is an essential component of the flagellum-specific protein export apparatus. It is an integral membrane protein. Its precise molecular function is unk [...]
CDM68791.1 protein networkhttps://string-db.org/network/1216932.CM240_1633Putative flagellar basal body-associated protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
CDM68792.1 protein networkhttps://string-db.org/network/1216932.CM240_1634Chemotaxis protein MotB; This is the MotB member of the E.coli MotA/MotB proton-channel complex that forms the stator of the bacterial membrane flagellar motor. Key residues act as a plug to prev [...]
CDM68793.1 protein networkhttps://string-db.org/network/1216932.CM240_1635Chemotaxis protein MotA; This family groups together integral membrane proteins that appear to be involved translocation of proteins across a membrane. These proteins are probably proton channels [...]
CDM68794.1 protein networkhttps://string-db.org/network/1216932.CM240_1636Flagellar protein flbD; This family consists of several bacterial FlbD flagellar proteins. The exact function of this family is unknown; Hypothetical protein.
CDM68795.1 protein networkhttps://string-db.org/network/1216932.CM240_1637Fagellar hook-basal body protein; Many bacterial species swim actively by means of flagella. The flagella organelle is made of three parts: the basal body, the hook and the filament. The basal bo [...]
CDM68796.1 protein networkhttps://string-db.org/network/1216932.CM240_1638Flagellar operon protein; This domain family is found in bacteria, and is approximately 20 amino acids in length. There is a conserved FTNID sequence motif. There is a single completely conserved [...]
CDM68797.1 protein networkhttps://string-db.org/network/1216932.CM240_1639Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.
CDM68798.1 protein networkhttps://string-db.org/network/1216932.CM240_1640Putative flagellar hook-length control protein; This is the C terminal domain of FliK. FliK controls the length of the flagellar hook by directly measuring the hook length as a molecular ruler. T [...]
CDM68799.1 protein networkhttps://string-db.org/network/1216932.CM240_1641Members of this family are the FliJ protein found,in nearly every case, in the midst of other flagellar biosynthesis genes in bacgterial genomes. Typically the fliJ gene is found adjacent to the [...]
fliI protein networkhttps://string-db.org/network/1216932.CM240_1642This family includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho; High confidence in function and specificity.
CDM68801.1 protein networkhttps://string-db.org/network/1216932.CM240_1643This entry represents a region found in the flagellar assembly protein FliH, as well as in type III secretion system protein HrpE. Many flagellar proteins are exported by a flagellum-specific exp [...]
fliG protein networkhttps://string-db.org/network/1216932.CM240_1644This is the N-terminal domain of the flagellar rotor protein FliG; High confidence in function and specificity.
CDM68803.1 protein networkhttps://string-db.org/network/1216932.CM240_1645Hypothetical protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
fliE protein networkhttps://string-db.org/network/1216932.CM240_1646fliE is a component of the flagellar hook-basal body complex located possibly at (MS-ring)-rod junction; Hypothetical protein.
CDM68805.1 protein networkhttps://string-db.org/network/1216932.CM240_1647Flagellar basal-body rod protein FlgC; In Salmonella typhimurium and related organisms the rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portio [...]
CDM68806.1 protein networkhttps://string-db.org/network/1216932.CM240_1648Flagellar basal body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
CDM68807.1 protein networkhttps://string-db.org/network/1216932.CM240_1649Acylneuraminate cytidylyltransferase (CMP-NeuAc synthetase) catalyzes the reaction of CTP and NeuAc to form CMP-NeuAc, which is the nucleotide sugar donor used by sialyltransferases. The outer me [...]
CDM68808.1 protein networkhttps://string-db.org/network/1216932.CM240_1650Flagellin family protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
CDM68809.1 protein networkhttps://string-db.org/network/1216932.CM240_1651Hypothetical protein; Family membership.
CDM68810.1 protein networkhttps://string-db.org/network/1216932.CM240_1652UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; This family of enzymes are aminotransferases of the pfam01041 family involved in the biosynthesis of pseudaminic acid. They convert UDP- [...]
CDM68811.1 protein networkhttps://string-db.org/network/1216932.CM240_1653NAD-dependent epimerase/dehydratase; This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions; High confi [...]
pseI protein networkhttps://string-db.org/network/1216932.CM240_1654Pseudaminic acid synthase; Catalyzes the fifth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Catalyzes the condensation of phosphoenolpy [...]
CDM68813.1 protein networkhttps://string-db.org/network/1216932.CM240_1655The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase and UDP-N-acetylglucosamine transferase. Structural analysis suggests the C-terminal domain contains the UDP-GlcNA [...]
CDM68814.1 protein networkhttps://string-db.org/network/1216932.CM240_1656Hypothetical protein; Family membership.
CDM68815.1 protein networkhttps://string-db.org/network/1216932.CM240_1657Hypothetical protein.
CDM68816.1 protein networkhttps://string-db.org/network/1216932.CM240_1658Putative glycosyltransferase; Mutations in this domain of P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrate [...]
CDM68817.1 protein networkhttps://string-db.org/network/1216932.CM240_1659Hypothetical protein; Family membership.
CDM68818.1 protein networkhttps://string-db.org/network/1216932.CM240_1660Hypothetical protein; Family membership.
CDM68819.1 protein networkhttps://string-db.org/network/1216932.CM240_1661Hypothetical protein; Family membership.
CDM68820.1 protein networkhttps://string-db.org/network/1216932.CM240_1662Hypothetical protein; High confidence in function and specificity.
CDM68821.1 protein networkhttps://string-db.org/network/1216932.CM240_1663Hypothetical protein; Family membership.
CDM68822.1 protein networkhttps://string-db.org/network/1216932.CM240_1664Carbamoylphosphate synthase large subunit; The ATP-grasp superfamily currently includes 17 groups of enzymes, catalyzing ATP-dependent ligation of a carboxylate containing molecule to an amino or [...]
CDM68823.1 protein networkhttps://string-db.org/network/1216932.CM240_1665DegT/DnrJ/EryC1/StrS aminotransferase; The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family include [...]
CDM68824.1 protein networkhttps://string-db.org/network/1216932.CM240_1666Hypothetical protein; This domain is characterised by two well-conserved short regions separated by a variable region in both sequence and length. The first of the two regions is found in a large [...]
CDM68825.1 protein networkhttps://string-db.org/network/1216932.CM240_1667HAD superfamily hydrolase; High confidence in function and specificity.
CDM68826.1 protein networkhttps://string-db.org/network/1216932.CM240_1668Carbamoyl phosphate synthetase catalyzes the ATP-dependent synthesis of carbamoyl phosphate from glutamine or ammonia and bicarbonate. This enzyme catalyzes the reaction of ATP and bicarbonate to [...]
CDM68827.1 protein networkhttps://string-db.org/network/1216932.CM240_1669Exopolysaccharide biosynthesis protein; This domain is found in diverse bacterial polysaccharide biosynthesis proteins including the CapD protein from Staphylococcus aureus, the WalL protein,mann [...]
CDM68828.1 protein networkhttps://string-db.org/network/1216932.CM240_1670Hypothetical protein.
CDM68829.1 protein networkhttps://string-db.org/network/1216932.CM240_1671Hypothetical protein.
hag1 protein networkhttps://string-db.org/network/1216932.CM240_1672Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
hag3 protein networkhttps://string-db.org/network/1216932.CM240_1673Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
CDM68832.1 protein networkhttps://string-db.org/network/1216932.CM240_1674Hypothetical protein.
CDM68833.1 protein networkhttps://string-db.org/network/1216932.CM240_1675Flagellar hook-associated protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filam [...]
CDM68834.1 protein networkhttps://string-db.org/network/1216932.CM240_1676Flagellar protein fliS; FliS is coded for by the FliD operon and is transcribed in conjunction with FliD and FliT, however this protein has no known function; Family membership.
CDM68835.1 protein networkhttps://string-db.org/network/1216932.CM240_1677Hypothetical protein.
CDM68836.1 protein networkhttps://string-db.org/network/1216932.CM240_1678Hypothetical protein; Family membership.
csrA protein networkhttps://string-db.org/network/1216932.CM240_1679Carbon storage regulator homolog; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno se [...]
fliW protein networkhttps://string-db.org/network/1216932.CM240_1680Flagellar assembly factor FliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and partici [...]
flgL protein networkhttps://string-db.org/network/1216932.CM240_1681This protein family consists of flagellar hook-associated proteins designated FlgL (or HAP3) encoded in bacterial flagellar operons. A N-terminal region of about 150 residues and a C-terminal reg [...]
flgK protein networkhttps://string-db.org/network/1216932.CM240_1682Flagellar hook-associated protein FlgK; In Salmonella typhimurium and related organisms the rod has been shown to consist of four different, yet evolutionary related proteins: in the distal porti [...]
CDM68841.1 protein networkhttps://string-db.org/network/1216932.CM240_1683Hypothetical protein.
CDM68842.1 protein networkhttps://string-db.org/network/1216932.CM240_1684Hypothetical protein.
Adsl protein networkhttps://string-db.org/network/1216932.CM240_1685Adenylosuccinate lyase; Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate (SAICAR) to fumarate plus 5- [...]
CDM68844.1 protein networkhttps://string-db.org/network/1216932.CM240_1686Putative membrane protein.
CDM68845.1 protein networkhttps://string-db.org/network/1216932.CM240_1687Phosphocarrier, HPr family; The histidine-containing phosphocarrier protein (HPr) is a central component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), which transfer [...]
aspB protein networkhttps://string-db.org/network/1216932.CM240_1688Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes,such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the bas [...]
CDM68847.1 protein networkhttps://string-db.org/network/1216932.CM240_1689Stage V sporulation protein S; In Bacillus subtilis this protein interferes with sporulation at an early stage and this inhibitory effect is overcome by SpoIIB and SpoVG. SpoVS seems to play a po [...]
rny protein networkhttps://string-db.org/network/1216932.CM240_1690Ribonuclease Y; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
recA protein networkhttps://string-db.org/network/1216932.CM240_1691Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of hom [...]
pgsA protein networkhttps://string-db.org/network/1216932.CM240_1692CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; All of these members have the ability to catalyse the displacement of CMP from a CDP-alcohol by a second alcohol with formation [...]
rimO protein networkhttps://string-db.org/network/1216932.CM240_1693Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
ftsK protein networkhttps://string-db.org/network/1216932.CM240_1694DNA translocase FtsK; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-termi [...]
tepA protein networkhttps://string-db.org/network/1216932.CM240_1695The Clp protease has an active site catalytic triad. In E. coli Clp protease, ser-111, his-136 and asp-185 form the catalytic triad. P48254 has lost all of these active site residues and is there [...]
dapG protein networkhttps://string-db.org/network/1216932.CM240_1696Aspartokinase 1; Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading [...]
pnp protein networkhttps://string-db.org/network/1216932.CM240_1697Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
rpsO protein networkhttps://string-db.org/network/1216932.CM240_169830S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
CDM68857.1 protein networkhttps://string-db.org/network/1216932.CM240_1699Riboflavin biosynthesis protein RibF; Riboflavin is converted into catalytically active cofactors (FAD and FMN) by the actions of riboflavin kinase (EC), which converts it into FMN, and FAD synth [...]
truB protein networkhttps://string-db.org/network/1216932.CM240_1700tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
CDM68859.1 protein networkhttps://string-db.org/network/1216932.CM240_1701It is predicted that this family of proteins all perform a phosphoesterase function. It included the single stranded DNA exonuclease RecJ; High confidence in function and specificity.
rbfA protein networkhttps://string-db.org/network/1216932.CM240_1702Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
infB protein networkhttps://string-db.org/network/1216932.CM240_1703Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
CDM68862.1 protein networkhttps://string-db.org/network/1216932.CM240_1704LSU ribosomal protein L7AE; This family includes: Ribosomal L7A from metazoa,Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from euka [...]
CDM68863.1 protein networkhttps://string-db.org/network/1216932.CM240_1705Hypothetical protein.
nusA protein networkhttps://string-db.org/network/1216932.CM240_1706Transcription elongation protein NusA; Participates in both transcription termination and antitermination.
rimP protein networkhttps://string-db.org/network/1216932.CM240_1707Ribosome maturation factor RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
polC protein networkhttps://string-db.org/network/1216932.CM240_1708DNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
ispG protein networkhttps://string-db.org/network/1216932.CM240_17094-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG fa [...]
rseP protein networkhttps://string-db.org/network/1216932.CM240_1710RIP metalloprotease RseP; Metalloproteases are the most diverse of the four main types of protease, with more than 50 families identified to date. In these enzymes, a divalent cation,usually zinc [...]
dxr protein networkhttps://string-db.org/network/1216932.CM240_17111-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Be [...]
CDM68870.1 protein networkhttps://string-db.org/network/1216932.CM240_1712Putative membrane protein.
cdsA protein networkhttps://string-db.org/network/1216932.CM240_1713CDP-diglyceride synthetase; Phosphatidate cytidylyltransferase (also known as CDP-diacylglycerol synthase) (CDS) is the enzyme that catalyzes the synthesis of CDP-diacylglycerol from cytidine tri [...]
uppS protein networkhttps://string-db.org/network/1216932.CM240_1714Isoprenyl transferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
frr protein networkhttps://string-db.org/network/1216932.CM240_1715Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
pyrH protein networkhttps://string-db.org/network/1216932.CM240_1716Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
tsf protein networkhttps://string-db.org/network/1216932.CM240_1717Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
rpsB protein networkhttps://string-db.org/network/1216932.CM240_1718Ribosomal protein S2 is one of the proteins from the small ribosomal subunit.S2 is a protein of 235 to 394 amino-acid residues. As signature patterns, we selected two conserved regions. One is lo [...]
codY protein networkhttps://string-db.org/network/1216932.CM240_1719GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth [...]
topA protein networkhttps://string-db.org/network/1216932.CM240_1720DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of [...]
CDM68879.1 protein networkhttps://string-db.org/network/1216932.CM240_1721The SMF family, of DNA processing chain A, dprA,are a group of bacterial proteins. In H. pylori, dprA is required for natural chromosomal and plasmid transformation. It has now been shown that Dp [...]
CDM68880.1 protein networkhttps://string-db.org/network/1216932.CM240_1722Putative Mg chelatase family protein; Magnesium-chelatase is a three-component enzyme that catalyses the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis o [...]
CDM68881.1 protein networkhttps://string-db.org/network/1216932.CM240_1723Hypothetical protein; Family membership; Belongs to the UPF0102 family.
rnhB protein networkhttps://string-db.org/network/1216932.CM240_1724Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
rbgA protein networkhttps://string-db.org/network/1216932.CM240_1725Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
rplS protein networkhttps://string-db.org/network/1216932.CM240_172650S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
trmD protein networkhttps://string-db.org/network/1216932.CM240_1727tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rimM protein networkhttps://string-db.org/network/1216932.CM240_1728Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. [...]
CDM68887.1 protein networkhttps://string-db.org/network/1216932.CM240_1729Hypothetical protein; Belongs to the UPF0109 family.
rpsP protein networkhttps://string-db.org/network/1216932.CM240_1730Ribosomal protein S16 is one of the proteins from the small ribosomal subunit.S16 is a protein of about 100 amino-acid residues. As a signature pattern, we selected a conserved region located in [...]
ffh protein networkhttps://string-db.org/network/1216932.CM240_1731Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nasce [...]
CDM68890.1 protein networkhttps://string-db.org/network/1216932.CM240_1732Hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
ftsY protein networkhttps://string-db.org/network/1216932.CM240_1733Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the [...]
smc protein networkhttps://string-db.org/network/1216932.CM240_1734Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family.
pflB protein networkhttps://string-db.org/network/1216932.CM240_1735Pyruvate formate lyase (PFL) catalyzes the non-oxidative conversion of pyruvate and CoA to formate and acetyl-CoA. Several other enzymes have been identified in the pyruvate formate lyase family: [...]
CDM68894.1 protein networkhttps://string-db.org/network/1216932.CM240_1736Hypothetical protein.
CDM68895.1 protein networkhttps://string-db.org/network/1216932.CM240_1737Putative membrane protein; High confidence in function and specificity.
CDM68896.1 protein networkhttps://string-db.org/network/1216932.CM240_1738MATE efflux family protein; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range of cati [...]
CDM68897.1 protein networkhttps://string-db.org/network/1216932.CM240_1739This domain appears to be a methyltransferase domain; High confidence in function and specificity.
CDM68898.1 protein networkhttps://string-db.org/network/1216932.CM240_1740Glycerophosphoryl diester phosphodiesterases display broad specificity for glycerophosphodiesters; glycerophosphocholine,glycerophosphoethanolamine, glycerophosphoglycerol, and bis(glycerophospho [...]
CDM68899.1 protein networkhttps://string-db.org/network/1216932.CM240_1741Putative membrane protein; High confidence in function and specificity.
CDM68900.1 protein networkhttps://string-db.org/network/1216932.CM240_1742Radical SAM proteins catalyse diverse reactions,including unusual methylations,isomerisation,sulphur insertion, ring formation, anaerobic oxidation and protein radical formation; High confidence [...]
CDM68901.1 protein networkhttps://string-db.org/network/1216932.CM240_1743Putative esterase; This family contains several seemingly unrelated proteins, including human esterase D; mycobacterial antigen 85, which is responsible for the high affinity of mycobacteria to f [...]
CDM68902.1 protein networkhttps://string-db.org/network/1216932.CM240_1744Drug resistance transporter, EmrB/QacA subfamily; This subfamily of drug efflux proteins, a part of the major facilitator family, is predicted to have 14 potential membrane-spanning regions. Memb [...]
CDM68903.1 protein networkhttps://string-db.org/network/1216932.CM240_1745Thermostable carboxypeptidase 2; This domain consists of 4 beta strands and two alpha helices which make up the dimerisation surface of members of the M20 family of peptidases.This family include [...]
CDM68904.1 protein networkhttps://string-db.org/network/1216932.CM240_1746L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
CDM68905.1 protein networkhttps://string-db.org/network/1216932.CM240_1747This entry represents a haemerythrin/HHE cation-binding domain that occurs as a duplicated domain in haemerythrins, myohemerythrins and related proteins. A bacterial protein, is a regulator of re [...]
CDM68906.1 protein networkhttps://string-db.org/network/1216932.CM240_1748Xanthine/uracil/vitamin C permease; High confidence in function and specificity.
ade2 protein networkhttps://string-db.org/network/1216932.CM240_1749Adenine deaminase 2; This protein hydrolyses adenine to form hypoxanthine and ammonia. Adenine deaminases reaction is important for adenine utilisation as a purine and also as a nitrogen source; [...]
ade1 protein networkhttps://string-db.org/network/1216932.CM240_1750Adenine deaminase hydrolyses adenine to form hypoxanthine and ammonia. Adenine deaminases reaction is important for adenine utilisation as a purine and also as a nitrogen source; High confidence [...]
CDM68909.1 protein networkhttps://string-db.org/network/1216932.CM240_1751ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM68910.1 protein networkhttps://string-db.org/network/1216932.CM240_1752ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDM68911.1 protein networkhttps://string-db.org/network/1216932.CM240_1753Two component transcriptional regulator, winged helix family; This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA b [...]
CDM68912.1 protein networkhttps://string-db.org/network/1216932.CM240_1754Integral membrane sensor signal transduction histidine kinase; The HAMP linker domain (present in Histidine kinases, Adenyl cyclases, Methyl-accepting proteins and Phosphatases) is an approximate [...]
ascB protein networkhttps://string-db.org/network/1216932.CM240_17556-phospho-beta-glucosidase AscB; Catalyzes the hydrolysis of phosphorylated beta-glucosides into glucose-6-phosphate (G-6-P) and aglycone. It has a high affinity for phosphorylated aromatic beta- [...]
bglP protein networkhttps://string-db.org/network/1216932.CM240_1756PTS system beta-glucoside-specific EIIBCA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the ph [...]
CDM68915.1 protein networkhttps://string-db.org/network/1216932.CM240_1757Transcriptional regulator, LysR family; Family membership; Belongs to the LysR transcriptional regulatory family.
CDM68916.1 protein networkhttps://string-db.org/network/1216932.CM240_1758Pyridine nucleotide-disulfide oxidoreductase domain protein; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small [...]
CDM68917.1 protein networkhttps://string-db.org/network/1216932.CM240_1759Pyridine nucleotide-disulfide oxidoreductase domain protein; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small [...]
CDM68918.1 protein networkhttps://string-db.org/network/1216932.CM240_1760Hypothetical protein; High confidence in function and specificity.
CDM68919.1 protein networkhttps://string-db.org/network/1216932.CM240_1761Hypothetical protein; High confidence in function and specificity.
CDM68920.1 protein networkhttps://string-db.org/network/1216932.CM240_1762Putative membrane protein; High confidence in function and specificity.
CDM68921.1 protein networkhttps://string-db.org/network/1216932.CM240_1763Hypothetical protein; High confidence in function and specificity.
CDM68922.1 protein networkhttps://string-db.org/network/1216932.CM240_1764Proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues [1,2,3]. The best studied of these proteins is the prokaryotic catabolite gene activator (also [...]
CDM68923.1 protein networkhttps://string-db.org/network/1216932.CM240_1765Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
cbh protein networkhttps://string-db.org/network/1216932.CM240_1766Choloylglycine hydrolase; High confidence in function and specificity.
CDM68925.1 protein networkhttps://string-db.org/network/1216932.CM240_1767Urease accessory protein UreI; This family includes UreI and proton gated urea channel as well as putative amide transporters; High confidence in function and specificity.
ureD protein networkhttps://string-db.org/network/1216932.CM240_1768Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
ureG protein networkhttps://string-db.org/network/1216932.CM240_1769Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
ureF protein networkhttps://string-db.org/network/1216932.CM240_1770Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
ureE protein networkhttps://string-db.org/network/1216932.CM240_1771Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
ureC protein networkhttps://string-db.org/network/1216932.CM240_1772Urease subunit alpha; Urease is a nickel-binding enzyme that catalyzes the hydrolysis of urea to carbon dioxide and ammonia. Historically, it was the first enzyme to be crystallized. It is mainly [...]
ureB protein networkhttps://string-db.org/network/1216932.CM240_1773Urease subunit beta; Urease is a nickel-binding enzyme that catalyses the hydrolysis of urea to carbon dioxide and ammonia: Urea + H2O = CO2 + 2 NH3; Family membership; Belongs to the urease beta [...]
ureA protein networkhttps://string-db.org/network/1216932.CM240_1774Urease subunit gamma; Urease catalyses the hydrolysis of urea to form ammonia and carbamate. The subunit composition of urease from different sources varies, but each holoenzyme consists of four [...]
CDM68933.1 protein networkhttps://string-db.org/network/1216932.CM240_1775Cobalamin; This family of proteins forms part of the cobalt-transport complex in prokaryotes, CbiMNQO. CbiMNQO and NikMNQO are the most widespread groups of microbial transporters for cobalt and [...]
CDM68934.1 protein networkhttps://string-db.org/network/1216932.CM240_1776Transcriptional regulator AraC family; This family represents the arabinose-binding and dimerisation domain of the bacterial gene regulatory protein AraC. The domain is found in conjunction with [...]
CDM68935.1 protein networkhttps://string-db.org/network/1216932.CM240_1777Putative MATE family multidrug efflux pumps; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a w [...]
CDM68936.1 protein networkhttps://string-db.org/network/1216932.CM240_1778Hypothetical protein; Family membership.
CDM68937.1 protein networkhttps://string-db.org/network/1216932.CM240_1779HAD hydrolase; The haloacid dehydrogenase (HAD) superfamily includes phosphatases, phosphonatases, P-type ATPases,beta-phosphoglucomutases, phosphomannomutases, and dehalogenases, which are invol [...]
CDM68938.1 protein networkhttps://string-db.org/network/1216932.CM240_1780Hypothetical protein; High confidence in function and specificity.
CDM68939.1 protein networkhttps://string-db.org/network/1216932.CM240_1781Hypothetical protein; High confidence in function and specificity.
CDM68940.1 protein networkhttps://string-db.org/network/1216932.CM240_1782Hypothetical protein; High confidence in function and specificity.
CDM68941.1 protein networkhttps://string-db.org/network/1216932.CM240_1783ABC transporter, permease protein; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological import and export systems [...]
CDM68942.1 protein networkhttps://string-db.org/network/1216932.CM240_1784MATE efflux family protein; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range of cati [...]
CDM68943.1 protein networkhttps://string-db.org/network/1216932.CM240_1785Transcriptional regulator MarR/EmrR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled b [...]
CDM68944.1 protein networkhttps://string-db.org/network/1216932.CM240_1786Putative membrane protein; High confidence in function and specificity.
CDM68946.1 protein networkhttps://string-db.org/network/1216932.CM240_1788Hypothetical protein; High confidence in function and specificity.
CDM68948.1 protein networkhttps://string-db.org/network/1216932.CM240_1790Hypothetical protein; Family membership.
CDM68949.1 protein networkhttps://string-db.org/network/1216932.CM240_1791Hypothetical protein; Family membership.
CDM68950.1 protein networkhttps://string-db.org/network/1216932.CM240_1792Beta-N-acetylhexosaminidase; Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; High confidence in function and specificity.
CDM68951.1 protein networkhttps://string-db.org/network/1216932.CM240_1793Hypothetical protein; Frameshift; Family membership.
CDM68952.1 protein networkhttps://string-db.org/network/1216932.CM240_1794Small, acid-soluble spore protein 1; SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone f [...]
hisE protein networkhttps://string-db.org/network/1216932.CM240_1795Phosphoribosyl-ATP pyrophosphatase; This enzyme catalyses the second step in the histidine biosynthetic pathway; Family membership.
CDM68954.1 protein networkhttps://string-db.org/network/1216932.CM240_1796Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family.
hisF protein networkhttps://string-db.org/network/1216932.CM240_1797Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that prod [...]
hisA protein networkhttps://string-db.org/network/1216932.CM240_17981-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; This protein family consists of HisA,phosphoribosylformimino-5-aminoimidazole carboxamide ribo [...]
hisH protein networkhttps://string-db.org/network/1216932.CM240_1799Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glu [...]
hisB protein networkhttps://string-db.org/network/1216932.CM240_1800Imidazoleglycerol-phosphate dehydratase is the enzyme that catalyzes the seventh step in the biosynthesis of histidine in bacteria, fungi and plants. In most organisms it is a monofunctional prot [...]
hisD protein networkhttps://string-db.org/network/1216932.CM240_1801Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisG protein networkhttps://string-db.org/network/1216932.CM240_1802ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
hisZ protein networkhttps://string-db.org/network/1216932.CM240_1803ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
CDM68963.1 protein networkhttps://string-db.org/network/1216932.CM240_1805Putative membrane protein.
gcp protein networkhttps://string-db.org/network/1216932.CM240_1806tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is [...]
CDM68965.1 protein networkhttps://string-db.org/network/1216932.CM240_1807Hypothetical protein.
CDM68966.1 protein networkhttps://string-db.org/network/1216932.CM240_1808Endodeoxyribonuclease RusA; This family consists of several bacterial and phage Holliday junction resolvase (RusA) like proteins. The RusA protein of Escherichia coli is an endonuclease that can [...]
CDM68967.1 protein networkhttps://string-db.org/network/1216932.CM240_1809Oxidoreductase; High confidence in function and specificity.
CDM68968.1 protein networkhttps://string-db.org/network/1216932.CM240_1810AsnC family transcriptional regulator; The asnC-type HTH domain is a DNA-binding,helix-turn-helix (HTH) domain of about 60 amino acids present in transcription regulators of the asnC/lrp family. [...]
CDM68969.1 protein networkhttps://string-db.org/network/1216932.CM240_1811Putative cellulase; High confidence in function and specificity; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CDM68970.1 protein networkhttps://string-db.org/network/1216932.CM240_1812Putative membrane protein; This domain is found in predicted permeases and hypothetical transmembrane proteins. SWISSPROT has been shown to transport lipids targeted to the outer membrane across [...]
bceA protein networkhttps://string-db.org/network/1216932.CM240_1813Part of the ABC transporter complex BceAB involved in bacitracin export. Responsible for energy coupling to the transport system; High confidence in function and specificity.
CDM68972.1 protein networkhttps://string-db.org/network/1216932.CM240_1814Sensor histidine kinase; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine protein kinase (HK) [...]
CDM68973.1 protein networkhttps://string-db.org/network/1216932.CM240_1815Hypothetical protein; This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain.
hslO1 protein networkhttps://string-db.org/network/1216932.CM240_1816Chaperone HSP33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial de [...]
CDM68976.1 protein networkhttps://string-db.org/network/1216932.CM240_1818Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide; High confidence in function and specificity.
ArtM3 protein networkhttps://string-db.org/network/1216932.CM240_1819ABC transporters belong to the ATP-Binding Cassette superfamily, which uses the hydrolysis of ATP to translocate a variety of compounds across biological membranes. ABC transporters are minimally [...]
CDM68978.1 protein networkhttps://string-db.org/network/1216932.CM240_1820Putative ABC transporter permease; Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two recip [...]
CDM68979.1 protein networkhttps://string-db.org/network/1216932.CM240_1821Amino acid ABC transporter; Bacterial high affinity transport systems are involved in active transport of solutes across the cytoplasmic membrane. The protein components of these traffic systems [...]
CDM68980.1 protein networkhttps://string-db.org/network/1216932.CM240_1822A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related. All contain a gly [...]
hisC3 protein networkhttps://string-db.org/network/1216932.CM240_1823Histidinol-phosphate aminotransferase, which catalyzes the eighth step in histidine biosynthetic pathway: the transfer of an amino group from 3-(imidazol-4-yl)-2-oxopropyl phosphate to glutamic a [...]
CDM68982.1 protein networkhttps://string-db.org/network/1216932.CM240_18244-aminobutyrate aminotransferase (GABA transaminase), which catalyzes the transfer of an amino group from GABA to alpha-ketoglutarate, yielding succinate semialdehyde and glutamic acid; High conf [...]
CDM68983.1 protein networkhttps://string-db.org/network/1216932.CM240_1825This group contains RocB of Bacillus subtilis and related proteins. RocB is one of the three genes found in the rocABC operon in B. subtilis, which is sigma L dependent and induced by arginine, s [...]
CDM68984.1 protein networkhttps://string-db.org/network/1216932.CM240_1826Transcriptional regulator; The gntR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 60-70 residues present in transcriptional regulators of the gntR family. This [...]
CDM68985.1 protein networkhttps://string-db.org/network/1216932.CM240_1827N-dimethylarginine dimethylaminohydrolase; Arginine deiminase [Amino acid transport and metabolism]; High confidence in function and specificity.
CDM68986.1 protein networkhttps://string-db.org/network/1216932.CM240_1828Putative methyl-accepting chemotaxis sensory transducer; Bacterial chemotactic-signal transducers [1,2] are proteins that respond to changes in the concentration of attractants and repellents in [...]
CDM68987.1 protein networkhttps://string-db.org/network/1216932.CM240_1829Hypothetical protein; Family membership.
glnT protein networkhttps://string-db.org/network/1216932.CM240_1830Sodium/alanine symporter family protein; It has been shown that integral membrane proteins that mediate the intake of a wide variety of molecules with the concomitant uptake of sodium ions (sodiu [...]
CDM68989.1 protein networkhttps://string-db.org/network/1216932.CM240_1831Acylphosphatase [1,2] catalyzes the hydrolysis of various acyl phosphate carboxyl-phosphate bonds such as carbamyl phosphate, succinyl phosphate,1,3-diphosphoglycerate, etc. The physiological rol [...]
idhM protein networkhttps://string-db.org/network/1216932.CM240_1832Isocitrate dehydrogenase (IDH) is an important enzyme of carbohydrate metabolism which catalyzes the oxidative decarboxylation of isocitrate into alpha-ketoglutarate. IDH is either dependent on N [...]
CDM68991.1 protein networkhttps://string-db.org/network/1216932.CM240_1833Putative transporter; CBS domains contain about 60 amino acid residues and occur as tandem pairs in a variety of proteins in bacteria,archaea, and eukaryotes. They are mainly found in proteins th [...]
CDM68992.1 protein networkhttps://string-db.org/network/1216932.CM240_1834The Multi Antimicrobial Extrusion (MATE) Family The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, [...]
CDM68993.1 protein networkhttps://string-db.org/network/1216932.CM240_1835Putative membrane protein.
CDM68994.1 protein networkhttps://string-db.org/network/1216932.CM240_1836Sensor histidine kinase; The HAMP linker domain (domain present in Histidine kinases, Adenyl cyclases, Methyl-accepting proteins and Phosphatases) is an approximately 50-amino acid alpha-helical [...]
CDM68995.1 protein networkhttps://string-db.org/network/1216932.CM240_1837Two component transcriptional regulator; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine pro [...]
YkpA protein networkhttps://string-db.org/network/1216932.CM240_1838ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM68997.1 protein networkhttps://string-db.org/network/1216932.CM240_1839Hypothetical protein; Family membership.
adhE protein networkhttps://string-db.org/network/1216932.CM240_1840Alcohol dehydrogenase (ADH) catalyzes the reversible oxidation of ethanol to acetaldehyde with the concomitant reduction of NAD; High confidence in function and specificity.
ydaH protein networkhttps://string-db.org/network/1216932.CM240_1841AbgT transporter family protein; AbgT expression is apparently cryptic in wild type cells, but when present on a high copy number plasmid, or when expressed at higher levels due to mutation, it a [...]
CDM69000.1 protein networkhttps://string-db.org/network/1216932.CM240_1842PfkB family kinase; This family includes a variety of carbohydrate and pyrimidine kinases; High confidence in function and specificity.
CDM69001.1 protein networkhttps://string-db.org/network/1216932.CM240_1843Hypothetical protein.
CDM69002.1 protein networkhttps://string-db.org/network/1216932.CM240_1844Hypothetical protein.
CDM69003.1 protein networkhttps://string-db.org/network/1216932.CM240_1845Hypothetical protein.
potD protein networkhttps://string-db.org/network/1216932.CM240_1846ABC transporter spermidine/putrescine solute-binding protein; Bacterial high affinity transport systems are involved in active transport of solutes across the cytoplasmic membrane. The protein co [...]
CDM69005.1 protein networkhttps://string-db.org/network/1216932.CM240_1847Spermidine/putrescine transport system permease protein PotC; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; High confidence in function and [...]
potB protein networkhttps://string-db.org/network/1216932.CM240_1848ABC transporter spermidine/putrescine permease; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; High confidence in function and specificity.
potA protein networkhttps://string-db.org/network/1216932.CM240_1849Spermidine/putrescine import ATP-binding protein PotA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport syste [...]
CDM69008.1 protein networkhttps://string-db.org/network/1216932.CM240_1850Transcriptional regulator, HTH; The cro/C1-type HTH domain is a DNA-binding,helix-turn-helix (HTH) domain of about 50-60 residues present in transcriptional regulators. The domain is named after [...]
CDM69009.1 protein networkhttps://string-db.org/network/1216932.CM240_1851Acetyltransferase, GNAT family; The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions [...]
CDM69010.1 protein networkhttps://string-db.org/network/1216932.CM240_1852Putative membrane protein.
CDM69011.1 protein networkhttps://string-db.org/network/1216932.CM240_1853Putative transmembrane protein; High confidence in function and specificity.
CDM69012.1 protein networkhttps://string-db.org/network/1216932.CM240_1854ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
ilvB3 protein networkhttps://string-db.org/network/1216932.CM240_1855Acetolactate synthase isozymes, large subunit; This type of acetolactate synthase catalyzes the formation of acetohydroxybutyrate from pyruvate and 2-oxobutyrate, an early step in the branched ch [...]
CDM69014.1 protein networkhttps://string-db.org/network/1216932.CM240_1856Acetolactate synthase, small subunit; These enzymes generally require thiamin diphosphate,FAD and a divalent metal ion for catalysis,though some enzymes specific for acetolactate synthesis do not [...]
CDM69015.1 protein networkhttps://string-db.org/network/1216932.CM240_1857ATP-dependent RNA helicase; Helicases have been classified in 5 superfamilies (SF1-SF5). For the two largest groups, commonly referred to as SF1 and SF2, a total of seven characteristic motifs ha [...]
CDM69016.1 protein networkhttps://string-db.org/network/1216932.CM240_1858This family of proteins are found in a range of bacteria. The conserved region contains a conserved histidine and cysteine, suggesting that these proteins have an enzymatic activity. Several memb [...]
CDM69017.1 protein networkhttps://string-db.org/network/1216932.CM240_1859Hypothetical protein; Family membership.
CDM69018.2 protein networkhttps://string-db.org/network/1216932.CM240_1860Alpha/beta hydrolase fold is common to a number of hydrolytic enzymes of widely differing phylogenetic origin and catalytic function.[1] The core of each enzyme is an alpha/beta-sheet (rather tha [...]
CDM69019.2 protein networkhttps://string-db.org/network/1216932.CM240_1861Hydrolase of alpha/beta superfamily; High confidence in function and specificity.
CDM69020.1 protein networkhttps://string-db.org/network/1216932.CM240_1862Putative membrane protein; High confidence in function and specificity.
CDM69021.1 protein networkhttps://string-db.org/network/1216932.CM240_1863This family consists of Carbon starvation protein CstA a predicted membrane protein. It has been suggested that CstA is involved in peptide utilisation; High confidence in function and specificit [...]
cobW protein networkhttps://string-db.org/network/1216932.CM240_1864Cobalamin synthesis protein; Cobalamin (vitamin B12) is a structurally complex cofactor, consisting of a modified tetrapyrrole with a centrally chelated cobalt. Cobalamin is usually found in one [...]
ydaD protein networkhttps://string-db.org/network/1216932.CM240_1865The short-chain dehydrogenases/reductases family (SDR) [1] is a very large family of enzymes, most of which are known to be NAD-or NADP-dependent oxidoreductases; High confidence in function and [...]
CDM69024.1 protein networkhttps://string-db.org/network/1216932.CM240_1866Hypothetical protein; Family membership.
CDM69025.1 protein networkhttps://string-db.org/network/1216932.CM240_1867Major facilitator family transporter; Among the different families of transporter, only two occur ubiquitously in all classifications of organisms. These are the ATP-Binding Cassette (ABC) superf [...]
CDM69026.1 protein networkhttps://string-db.org/network/1216932.CM240_1868Hypothetical protein; High confidence in function and specificity.
CDM69027.1 protein networkhttps://string-db.org/network/1216932.CM240_1869This family includes a variety of exonuclease proteins, such as ribonuclease T and the epsilon subunit of DNA polymerase III; High confidence in function and specificity.
CDM69028.1 protein networkhttps://string-db.org/network/1216932.CM240_1870Putative Myosin-cross-reactive antigen family protein; Members of this family are thought to have structural features in common with the beta chain of the class II antigens; High confidence in fu [...]
CDM69029.1 protein networkhttps://string-db.org/network/1216932.CM240_1871This family includes integral membrane proteins,some of which are NA+/H+ antiporters; High confidence in function and specificity.
dedA protein networkhttps://string-db.org/network/1216932.CM240_1872Protein DedA; High confidence in function and specificity.
CDM69031.1 protein networkhttps://string-db.org/network/1216932.CM240_1873O-acetylhomoserine (thiol)-lyase; This family of sequences is a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulf [...]
CDM69032.1 protein networkhttps://string-db.org/network/1216932.CM240_1874Hypothetical protein; Family membership.
aat protein networkhttps://string-db.org/network/1216932.CM240_1875Leucyl/phenylalanyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-ter [...]
CDM69034.1 protein networkhttps://string-db.org/network/1216932.CM240_1876Putative membrane protein.
CDM69035.1 protein networkhttps://string-db.org/network/1216932.CM240_1877Transcriptional regulator, CarD family; CarD is a Myxococcus xanthus protein required for the activation of light-and starvation-inducible genes; Family membership.
CDM69036.1 protein networkhttps://string-db.org/network/1216932.CM240_1878Putative membrane protein; Family membership.
CDM69037.1 protein networkhttps://string-db.org/network/1216932.CM240_1879Ferredoxin-dependent glutamate synthases have been implicated in a number of functions including photorespiration in Arabidopsis where they may also play a role in primary nitrogen assimilation i [...]
CDM69038.1 protein networkhttps://string-db.org/network/1216932.CM240_1880Nicotinate phosphoribosyltransferase is the rate limiting enzyme that catalyses the first reaction in the NAD salvage synthesis. This family also includes Pre-B cell enhancing factor that is a cy [...]
CDM69039.1 protein networkhttps://string-db.org/network/1216932.CM240_1881Amidase; Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide [...]
CDM69040.1 protein networkhttps://string-db.org/network/1216932.CM240_1882Ribose-phosphate pyrophosphokinase; The name PRT comes from phosphoribosyltransferase (PRTase) enzymes, which carry out phosphoryl transfer reactions on 5-phosphoribosyl-alpha1-pyrophosphate PRPP [...]
CDM69041.1 protein networkhttps://string-db.org/network/1216932.CM240_1883The Nudix family is a protein family of phosphohydrolases. Using water-mediated catalysis they break a phosphate bond in their substrate to create two products. Nudix stands for Nucleoside Diphos [...]
CDM69042.1 protein networkhttps://string-db.org/network/1216932.CM240_1884Hypothetical protein; High confidence in function and specificity.
CDM69043.1 protein networkhttps://string-db.org/network/1216932.CM240_1885Putative membrane protein; High confidence in function and specificity.
CDM69044.1 protein networkhttps://string-db.org/network/1216932.CM240_1886Hypothetical protein; High confidence in function and specificity.
CDM69045.1 protein networkhttps://string-db.org/network/1216932.CM240_1887Accessory gene regulator protein C; Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; High confidence in function and specificity.
agrA protein networkhttps://string-db.org/network/1216932.CM240_1888Accessory gene regulator A; This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain; High confi [...]
CDM69047.1 protein networkhttps://string-db.org/network/1216932.CM240_1889Putative membrane protein; Family membership.
CDM69048.1 protein networkhttps://string-db.org/network/1216932.CM240_1890Hypothetical protein; Family membership; Belongs to the glycosyl hydrolase 13 family.
CDM69049.1 protein networkhttps://string-db.org/network/1216932.CM240_1891A N-acetylmuramoyl-L-alanine amidase is an enzyme that catalyzes a chemical reaction that cleaves the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycope [...]
CDM69050.1 protein networkhttps://string-db.org/network/1216932.CM240_1892Hypothetical protein.
CDM69051.1 protein networkhttps://string-db.org/network/1216932.CM240_1893Stage V sporulation protein S; In Bacillus subtilis this protein interferes with sporulation at an early stage and this inhibitory effect is overcome by SpoIIB and SpoVG. SpoVS seems to play a po [...]
CDM69052.1 protein networkhttps://string-db.org/network/1216932.CM240_1894Radical SAM proteins catalyse diverse reactions,including unusual methylations,isomerisation,sulphur insertion, ring formation, anaerobic oxidation and protein radical formation; Conserved hypoth [...]
rnc protein networkhttps://string-db.org/network/1216932.CM240_1895Ribonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRN [...]
acpP-2 protein networkhttps://string-db.org/network/1216932.CM240_1896Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
plsX protein networkhttps://string-db.org/network/1216932.CM240_1897Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but n [...]
rpmF protein networkhttps://string-db.org/network/1216932.CM240_189850S ribosomal protein L32; Most of the proteins interact with multiple RNA elements, often from different domains. In the large subunit, about 1/3 of the 23S rRNA nucleotides are at least in van [...]
CDM69057.1 protein networkhttps://string-db.org/network/1216932.CM240_1899Hypothetical protein.
ackA protein networkhttps://string-db.org/network/1216932.CM240_1900Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
pta protein networkhttps://string-db.org/network/1216932.CM240_1901This family contains both phosphate acetyltransferase and phosphate butaryltransferase. These enzymes catalyse the transfer of an acetyl or butaryl group to orthophosphate; High confidence in fun [...]
tmcAL protein networkhttps://string-db.org/network/1216932.CM240_1902Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to [...]
CDM69061.1 protein networkhttps://string-db.org/network/1216932.CM240_1903Putative membrane protein; High confidence in function and specificity.
CDM69062.1 protein networkhttps://string-db.org/network/1216932.CM240_1904Members of this family are transcriptional regulators that appear to be related to the PF01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic aci [...]
CDM69063.1 protein networkhttps://string-db.org/network/1216932.CM240_1905Hypothetical protein; High confidence in function and specificity.
CDM69064.1 protein networkhttps://string-db.org/network/1216932.CM240_1906Hypothetical protein; Family membership.
coaD protein networkhttps://string-db.org/network/1216932.CM240_1907Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD [...]
CDM69066.1 protein networkhttps://string-db.org/network/1216932.CM240_1908RNA methyltransferase, RsmD family; This entry contains Ribosomal RNA small subunit methyltransferase D as well as the putative rRNA methyltransferase YlbH. They methylate the guanosine in positi [...]
recG protein networkhttps://string-db.org/network/1216932.CM240_1909ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwindin [...]
yloV protein networkhttps://string-db.org/network/1216932.CM240_1910DAK2 domain protein; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family; High confidence in function and specificity.
CDM69069.1 protein networkhttps://string-db.org/network/1216932.CM240_1911Putative alkaline shock protein; A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using [...]
rpmB protein networkhttps://string-db.org/network/1216932.CM240_1912The ribosomal 28 family includes L28 proteins from bacteria and chloroplasts. The L24 protein from yeast P36525 also contains a region of similarity to prokaryotic L28 proteins. L24 from yeast is [...]
CDM69071.1 protein networkhttps://string-db.org/network/1216932.CM240_1913Thiamine diphosphokinase; Family of thiamin pyrophosphokinase (. Thiamin pyrophosphokinase (TPK) catalyses the transfer of a pyrophosphate group from ATP to vitamin B1 (thiamin) to form the coenz [...]
rpe protein networkhttps://string-db.org/network/1216932.CM240_1914Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate; High confidence in function and specificity; Belongs to the ribulose-ph [...]
rsgA protein networkhttps://string-db.org/network/1216932.CM240_1915Putative ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subu [...]
CDM69074.1 protein networkhttps://string-db.org/network/1216932.CM240_1916The protein kinase domain is a structurally conserved protein domain containing the catalytic function of protein kinases.[2][3][4] Protein kinases are a group of enzymes that move a phosphate gr [...]
CDM69075.1 protein networkhttps://string-db.org/network/1216932.CM240_1917Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase; High confidence in function and specificity.
rlmN protein networkhttps://string-db.org/network/1216932.CM240_1918Putative dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. [...]
CDM69077.1 protein networkhttps://string-db.org/network/1216932.CM240_1919Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
fmt protein networkhttps://string-db.org/network/1216932.CM240_1920Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
def protein networkhttps://string-db.org/network/1216932.CM240_1921Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
priA protein networkhttps://string-db.org/network/1216932.CM240_1922Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex [...]
coaBC protein networkhttps://string-db.org/network/1216932.CM240_1923Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoyl [...]
rpoZ protein networkhttps://string-db.org/network/1216932.CM240_1924Putative RNAP omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
gmk protein networkhttps://string-db.org/network/1216932.CM240_1925Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
CDM69084.1 protein networkhttps://string-db.org/network/1216932.CM240_1926Hypothetical protein; High confidence in function and specificity; Belongs to the RemA family.
CDM69085.1 protein networkhttps://string-db.org/network/1216932.CM240_1927Hypothetical protein; High confidence in function and specificity.
ansA protein networkhttps://string-db.org/network/1216932.CM240_1928L-asparaginase; Asparaginase is an enzyme that catalyzes the hydrolysis of asparagine to aspartic acid. Asparaginases are naturally occurring enzymes expressed and produced by microorganisms; Hig [...]
CDM69087.1 protein networkhttps://string-db.org/network/1216932.CM240_1929Renal dipeptidase (rDP), also known as microsomal dipeptidase or membrane dipeptidase, is a zinc-dependent metalloenzyme which hydrolyzes a wide range of dipeptides. It is involved in renal metab [...]
spoIVA protein networkhttps://string-db.org/network/1216932.CM240_1930Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
gpsA protein networkhttps://string-db.org/network/1216932.CM240_1931Glycerol-3-phosphate dehydrogenase (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate (aka glycerone phosphate,outdated) to sn-glycerol 3-phosphate; [...]
der protein networkhttps://string-db.org/network/1216932.CM240_1932GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
CDM69091.1 protein networkhttps://string-db.org/network/1216932.CM240_1933Hypothetical protein; High confidence in function and specificity.
CDM69092.1 protein networkhttps://string-db.org/network/1216932.CM240_1934Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS [...]
CDM69093.1 protein networkhttps://string-db.org/network/1216932.CM240_1935Transposase; The integrase catalytic domain catalyzes a series of reactions to integrate the viral genome into a host chromosome. In the first step, it removes two 3' end nucleotides from each st [...]
phoU protein networkhttps://string-db.org/network/1216932.CM240_1936Phosphate-specific transport system accessory protein PhoU homolog; Plays a role in the regulation of phosphate uptake.
pstB protein networkhttps://string-db.org/network/1216932.CM240_1937Phosphate import ATP-binding protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC tr [...]
CDM69096.1 protein networkhttps://string-db.org/network/1216932.CM240_1938ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological import and export systems. ABC transporters are minimally con [...]
CDM69097.1 protein networkhttps://string-db.org/network/1216932.CM240_1939Phosphate ABC transporter, inner membrane subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across th [...]
CDM69098.1 protein networkhttps://string-db.org/network/1216932.CM240_1940Phosphate-binding periplasmic protein; High confidence in function and specificity.
CDM69099.1 protein networkhttps://string-db.org/network/1216932.CM240_1941Sensor histidine kinase; The HAMP linker domain (present in Histidine kinases, Adenyl cyclases, Methyl-accepting proteins and Phosphatases) is an approximately 50-amino acid alpha-helical region. [...]
phoP protein networkhttps://string-db.org/network/1216932.CM240_1942Transcriptional regulatory protein; Two-component signal transduction systems enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; High [...]
CDM69101.1 protein networkhttps://string-db.org/network/1216932.CM240_1943Hypothetical protein; High confidence in function and specificity; Belongs to the multicopper oxidase YfiH/RL5 family.
nrdR protein networkhttps://string-db.org/network/1216932.CM240_1944Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
CDM69103.1 protein networkhttps://string-db.org/network/1216932.CM240_1945Hypothetical protein.
sigG protein networkhttps://string-db.org/network/1216932.CM240_1946RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
sigE protein networkhttps://string-db.org/network/1216932.CM240_1947RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
CDM69106.1 protein networkhttps://string-db.org/network/1216932.CM240_1948sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide i [...]
ftsZ protein networkhttps://string-db.org/network/1216932.CM240_1949Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
ftsA protein networkhttps://string-db.org/network/1216932.CM240_1950Cell division protein ftsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
CDM69109.1 protein networkhttps://string-db.org/network/1216932.CM240_1951Glycosyltransferases, probably involved in cell wall biogenesis; High confidence in function and specificity.
pilT protein networkhttps://string-db.org/network/1216932.CM240_1952Twitching mobility protein; A number of bacterial proteins, some of which are involved in a general secretion pathway (GSP) for the export of proteins (also called the type II pathway) belong to [...]
sigK protein networkhttps://string-db.org/network/1216932.CM240_1953RNA polymerase sigma-28 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
udk protein networkhttps://string-db.org/network/1216932.CM240_1954Uridine kinase (pyrimidine ribonucleoside kinase) is the rate-limiting enzyme in the pyrimidine salvage pathway; High confidence in function and specificity.
yrrO protein networkhttps://string-db.org/network/1216932.CM240_1955Putative protease YrrO; High confidence in function and specificity.
CDM69114.1 protein networkhttps://string-db.org/network/1216932.CM240_1956O-methyltransferase family protein; Methyltransferases constitute an important class of enzymes present in every life form. They transfer a methyl group most frequently from S-adenosyl L-methioni [...]
mltG protein networkhttps://string-db.org/network/1216932.CM240_1957Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
typA protein networkhttps://string-db.org/network/1216932.CM240_1958GTP-binding protein TypA/BipA homolog; Probably interacts with the ribosomes in a GTP dependent manner. GTPase that mediates interactions between enteropathogenic E.coli (EPEC) and epithelial cel [...]
rnjA protein networkhttps://string-db.org/network/1216932.CM240_1959Ribonuclease J 1; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
CDM69118.1 protein networkhttps://string-db.org/network/1216932.CM240_1960This family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes. This family is also known as the FUR family; High [...]
CDM69119.1 protein networkhttps://string-db.org/network/1216932.CM240_1961Hypothetical protein.
CDM69120.1 protein networkhttps://string-db.org/network/1216932.CM240_1962Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
CDM69121.1 protein networkhttps://string-db.org/network/1216932.CM240_1963Hypothetical protein; Family membership; Belongs to the UPF0297 family.
alaS protein networkhttps://string-db.org/network/1216932.CM240_1964Alanine-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(A [...]
CDM69123.1 protein networkhttps://string-db.org/network/1216932.CM240_1965Hypothetical protein; Family membership.
CDM69124.1 protein networkhttps://string-db.org/network/1216932.CM240_1966Hypothetical protein; Family membership.
CDM69125.1 protein networkhttps://string-db.org/network/1216932.CM240_1967Hypothetical protein; Family membership.
CDM69126.1 protein networkhttps://string-db.org/network/1216932.CM240_1968Putative membrane protein.
CDM69127.1 protein networkhttps://string-db.org/network/1216932.CM240_1969Hypothetical protein.
mnmA protein networkhttps://string-db.org/network/1216932.CM240_1970tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
CDM69129.1 protein networkhttps://string-db.org/network/1216932.CM240_1971NifU-like protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; High confidence in function and specificity.
iscS protein networkhttps://string-db.org/network/1216932.CM240_1972Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental [...]
CDM69131.1 protein networkhttps://string-db.org/network/1216932.CM240_1973This entry represents transcriptional regulators such as Desulfovibrio vulgaris Protein Rrf2, Escherichia coli IscR and Bacillus subtilis NsrR. Protein Rrf2 is a repressor of the hmc operon encod [...]
hom protein networkhttps://string-db.org/network/1216932.CM240_1974Homoserine dehydrogenase catalyzes NAD-dependent reduction of aspartate beta-semialdehyde into homoserine. This reaction is the third step in a pathway leading from aspartate to homoserine. The l [...]
thrB protein networkhttps://string-db.org/network/1216932.CM240_1975Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
CDM69134.1 protein networkhttps://string-db.org/network/1216932.CM240_1976Threonine synthase; Shikimate kinase is an enzyme that catalyzes the ATP-dependent phosphorylation of shikimate to form shikimate 3-phosphate. This reaction is the fifth step of the shikimate pat [...]
CDM69135.1 protein networkhttps://string-db.org/network/1216932.CM240_1977Hypothetical protein; Family membership.
CDM69136.1 protein networkhttps://string-db.org/network/1216932.CM240_1978Hypothetical protein; Family membership.
greA-3 protein networkhttps://string-db.org/network/1216932.CM240_1979Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
CDM69138.1 protein networkhttps://string-db.org/network/1216932.CM240_1980Putative membrane protein.
yrvN protein networkhttps://string-db.org/network/1216932.CM240_1981Replication-associated recombination protein A; High confidence in function and specificity.
CDM69140.1 protein networkhttps://string-db.org/network/1216932.CM240_1982Putative membrane protein; High confidence in function and specificity; Belongs to the BI1 family.
act protein networkhttps://string-db.org/network/1216932.CM240_1983Pyruvate formate-lyase-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodo [...]
pfl protein networkhttps://string-db.org/network/1216932.CM240_1984Pyruvate formate lyase catalyzes the non-oxidative conversion of pyruvate and CoA to formate and acetyl-CoA. Several other enzymes have been identified in the pyruvate formate lyase family: ketoa [...]
CDM69143.1 protein networkhttps://string-db.org/network/1216932.CM240_1985The HD domain is a conserved protein domain. It is found in a superfamily of enzymes with a predicted or known phosphohydrolase activity. These enzymes appear to be involved in nucleic acid metab [...]
addA protein networkhttps://string-db.org/network/1216932.CM240_1986ATP-dependent helicase/nuclease subunit A; ATP-dependent DNA helicase.
CDM69145.1 protein networkhttps://string-db.org/network/1216932.CM240_1987ATP-dependent nuclease subunit B; ATP-dependent DNA helicase.
glyA protein networkhttps://string-db.org/network/1216932.CM240_1988Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
CDM69147.1 protein networkhttps://string-db.org/network/1216932.CM240_1989Putative membrane protein; High confidence in function and specificity.
CDM69148.1 protein networkhttps://string-db.org/network/1216932.CM240_1990Putative membrane protein; Family membership.
CDM69149.1 protein networkhttps://string-db.org/network/1216932.CM240_1991Integral membrane protein; High confidence in function and specificity.
CDM69150.1 protein networkhttps://string-db.org/network/1216932.CM240_1992Hypothetical protein.
malQ protein networkhttps://string-db.org/network/1216932.CM240_19934-alpha-glucanotransferase; High confidence in function and specificity.
CDM69152.1 protein networkhttps://string-db.org/network/1216932.CM240_1994Transcriptional regulator, LacI family; Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may [...]
CDM69153.1 protein networkhttps://string-db.org/network/1216932.CM240_1995Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane; Hypothetical protein.
CDM69154.1 protein networkhttps://string-db.org/network/1216932.CM240_1996Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane; Hypothetical protein.
CDM69155.1 protein networkhttps://string-db.org/network/1216932.CM240_1997Putative maltose/maltodextrin ABC transporter; Maltodextrin binding protein (MBP) is the primary component of bacterial high-affinity active transport and chemotaxis; Family membership.
CDM69156.1 protein networkhttps://string-db.org/network/1216932.CM240_1998Hypothetical protein; Family membership.
msmX protein networkhttps://string-db.org/network/1216932.CM240_1999Maltodextrin import ATP-binding protein MsmX; Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for energy coupling to the transport system; High confidenc [...]
aspS3 protein networkhttps://string-db.org/network/1216932.CM240_2000Aspartate-tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end [...]
hisS protein networkhttps://string-db.org/network/1216932.CM240_2001Histidine-tRNA ligase (also known as histidyl-tRNA synthetase) is an alpha2 dimer that belongs to class IIa. Every completed genome includes a histidine-tRNA ligase. Apparent second copies from B [...]
CDM69160.1 protein networkhttps://string-db.org/network/1216932.CM240_2002Coproporphyrinogen oxidase uses S-adenosyl-L-methionine (AdoMet) instead of oxygen as oxidant. It occurs mainly in bacteria, whereas eukaryotes use the oxygen-dependent oxidase. The reaction star [...]
CDM69161.1 protein networkhttps://string-db.org/network/1216932.CM240_2003The metallo-beta-lactamase protein fold is a protein domain contained in class B beta-lactamases and a number of other proteins.These proteins include thiolesterases,members of the glyoxalase II [...]
dtd protein networkhttps://string-db.org/network/1216932.CM240_2004D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischar [...]
relA protein networkhttps://string-db.org/network/1216932.CM240_2005GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to chan [...]
apt protein networkhttps://string-db.org/network/1216932.CM240_2006Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
CDM69165.1 protein networkhttps://string-db.org/network/1216932.CM240_2007It is predicted that this family of proteins all perform a phosphoesterase function. It included the single stranded DNA exonuclease RecJ; High confidence in function and specificity.
secF protein networkhttps://string-db.org/network/1216932.CM240_2008Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein [...]
secD protein networkhttps://string-db.org/network/1216932.CM240_2009Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete pro [...]
CDM69168.1 protein networkhttps://string-db.org/network/1216932.CM240_2010Heme biosynthesis; Radical SAM proteins catalyse diverse reactions,including unusual methylations,isomerisation,sulphur insertion, ring formation, anaerobic oxidation and protein radical formatio [...]
CDM69169.1 protein networkhttps://string-db.org/network/1216932.CM240_2011Hypothetical protein; Family membership.
CDM69170.1 protein networkhttps://string-db.org/network/1216932.CM240_2012Putative membrane protein.
CDM69171.1 protein networkhttps://string-db.org/network/1216932.CM240_2013Hypothetical protein; Family membership.
tgt protein networkhttps://string-db.org/network/1216932.CM240_2014Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in [...]
queA protein networkhttps://string-db.org/network/1216932.CM240_2015S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ [...]
ruvB protein networkhttps://string-db.org/network/1216932.CM240_2016Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may [...]
ruvA protein networkhttps://string-db.org/network/1216932.CM240_2017Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand [...]
CDM69176.1 protein networkhttps://string-db.org/network/1216932.CM240_2018Hypothetical protein; Family membership.
CDM69177.1 protein networkhttps://string-db.org/network/1216932.CM240_2019Hypothetical protein membrane; Family membership.
CDM69178.1 protein networkhttps://string-db.org/network/1216932.CM240_2020Putative transcriptional regulatory protein Cbei_4222; This is a family of transcriptional regulators. In mammals, it activates the transcription of mitochondrially-encoded COX1 [2]. In bacteria, [...]
CDM69179.1 protein networkhttps://string-db.org/network/1216932.CM240_2021Hypothetical protein; High confidence in function and specificity.
CDM69180.1 protein networkhttps://string-db.org/network/1216932.CM240_2022Putative membrane protein; High confidence in function and specificity.
CDM69181.1 protein networkhttps://string-db.org/network/1216932.CM240_2023ABC transporters belong to the ATP-Binding Cassette superfamily, which uses the hydrolysis of ATP to translocate a variety of compounds across biological membranes. ABC transporters are minimally [...]
CDM69182.2 protein networkhttps://string-db.org/network/1216932.CM240_2024Hypothetical protein; High confidence in function and specificity.
CDM69183.1 protein networkhttps://string-db.org/network/1216932.CM240_2025Transcriptional regulator; The GntR-like bacterial transcription factors are a family of transcription factors, Many bacterial transcription regulation proteins bind DNA through a helix-turn-heli [...]
CDM69184.1 protein networkhttps://string-db.org/network/1216932.CM240_2026Hypothetical protein; High confidence in function and specificity.
hflX protein networkhttps://string-db.org/network/1216932.CM240_2027GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
CDM69186.1 protein networkhttps://string-db.org/network/1216932.CM240_2028Penicillin-binding proteins (PBPs) are a group of proteins that are characterized by their affinity for and binding of penicillin. They are a normal constituent of many bacteria; the name just re [...]
CDM69187.1 protein networkhttps://string-db.org/network/1216932.CM240_2029Stage V sporulation protein AE; Members of this family are all described as putative stage V sporulation protein AE, although this could not be confirmed. Proteins in this family are approximatel [...]
CDM69188.1 protein networkhttps://string-db.org/network/1216932.CM240_2030Putative membrane protein.
CDM69189.1 protein networkhttps://string-db.org/network/1216932.CM240_2031This family contains the bacterial stage V sporulation protein AD (SpoVAD), which is approximately 340 residues long. This is one of six proteins encoded by the spoVA operon, which is transcribed [...]
CDM69190.1 protein networkhttps://string-db.org/network/1216932.CM240_2032Sporulation stage V, protein AC; Members of this family are all transcribed from the spoVA operon. These proteins are poorly characterised, but are thought to be involved in dipicolinic acid tran [...]
sigF protein networkhttps://string-db.org/network/1216932.CM240_2033RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
spoIIAB protein networkhttps://string-db.org/network/1216932.CM240_2034Putative anti-sigma regulatory factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation m [...]
CDM69193.1 protein networkhttps://string-db.org/network/1216932.CM240_2035The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been sug [...]
luxS protein networkhttps://string-db.org/network/1216932.CM240_2036S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the en [...]
CDM69195.1 protein networkhttps://string-db.org/network/1216932.CM240_2037This domain is found at the C terminus of the TaqI protein and other modification methylases and is involved in DNA-binding and substrate recognition; High confidence in function and specificity.
CDM69196.1 protein networkhttps://string-db.org/network/1216932.CM240_2038Delta-lactam-biosynthetic de-N-acetylase; This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which [...]
CDM69198.1 protein networkhttps://string-db.org/network/1216932.CM240_2040Formiminotransferase-cyclodeaminase; This enzymes containing the cyclodeaminase domain function in channeling one-carbon units to the folate pool. In most cases, this domain acts as a formimidoyl [...]
CDM69199.1 protein networkhttps://string-db.org/network/1216932.CM240_2041Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
SpsK protein networkhttps://string-db.org/network/1216932.CM240_2042Dtdp-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
CDM69201.1 protein networkhttps://string-db.org/network/1216932.CM240_2043Membrane protein; High confidence in function and specificity.
CDM69202.1 protein networkhttps://string-db.org/network/1216932.CM240_2044Cell envelope-related transcriptional attenuato; Domain of unknown function that is found in the predicted extracellular domain of a number of putative membrane-bound proteins. One of these is pr [...]
CDM69203.1 protein networkhttps://string-db.org/network/1216932.CM240_2045N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid [...]
gtaB protein networkhttps://string-db.org/network/1216932.CM240_2046UTP-glucose-1-phosphate uridylyltransferase; Nucleotidyl transferases transfer nucleotides from one compound to another. This domain is found in a number of enzymes that transfer nucleotides onto [...]
CDM69205.1 protein networkhttps://string-db.org/network/1216932.CM240_2047Hypothetical protein; High confidence in function and specificity.
pgcA protein networkhttps://string-db.org/network/1216932.CM240_2048Phosphoglucomutase (PGM). PGM is an enzyme responsible for the conversion of D-glucose 1-phosphate into D-glucose 6-phosphate. PGM participates in both the breakdown and synthesis of glucose; Hig [...]
CDM69207.1 protein networkhttps://string-db.org/network/1216932.CM240_2049Hypothetical protein; Family membership.
CDM69208.1 protein networkhttps://string-db.org/network/1216932.CM240_2050Hypothetical protein; Family membership.
CDM69209.1 protein networkhttps://string-db.org/network/1216932.CM240_2051CDP- glycerol:poly(Glycerophosphate)glycerophosphotransferase; Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall pept [...]
CDM69210.1 protein networkhttps://string-db.org/network/1216932.CM240_2052CDP-glycerol glycerophosphotransferase; Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-posit [...]
CDM69211.1 protein networkhttps://string-db.org/network/1216932.CM240_2053Putative protein; Mutations in this domain of P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including [...]
CDM69212.1 protein networkhttps://string-db.org/network/1216932.CM240_2054Glycerol-3-phosphate cytidylyltransferase; Provides activated glycerol phosphate for teichoic acid synthesis, via incorporation into both the linkage unit and the teichoic acid polymer by TagB an [...]
CDM69213.1 protein networkhttps://string-db.org/network/1216932.CM240_2055Hypothetical protein; Family membership.
CDM69214.1 protein networkhttps://string-db.org/network/1216932.CM240_2056Putative membrane protein; High confidence in function and specificity.
CDM69215.2 protein networkhttps://string-db.org/network/1216932.CM240_2057Glycosyl transferase group 1; The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the [...]
CDM69216.1 protein networkhttps://string-db.org/network/1216932.CM240_2058Glycosyltransferase; The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the transfer [...]
CDM69217.1 protein networkhttps://string-db.org/network/1216932.CM240_2059Hypothetical protein; Family membership.
CDM69218.1 protein networkhttps://string-db.org/network/1216932.CM240_2060Hypothetical protein.
CDM69219.1 protein networkhttps://string-db.org/network/1216932.CM240_2061Hypothetical protein.
CDM69220.1 protein networkhttps://string-db.org/network/1216932.CM240_2062In Bacillus subtilis, LytR is described as a transcriptional attenuator of itself and the LytABC operon,where LytC is N-acetylmuramoyl-L-alanine amidase. A third is CpsA, a putative regulatory pr [...]
CDM69221.1 protein networkhttps://string-db.org/network/1216932.CM240_2063Mannose-6-phosphate isomerase or phosphomannose isomerase (PMI) is the enzyme that catalyses the interconversion of mannose-6-phosphate and fructose-6-phosphate. In eukaryotes PMI is involved in [...]
CDM69222.1 protein networkhttps://string-db.org/network/1216932.CM240_2064Hypothetical protein; High confidence in function and specificity.
CDM69223.1 protein networkhttps://string-db.org/network/1216932.CM240_2065Putative membrane protein.
CDM69224.1 protein networkhttps://string-db.org/network/1216932.CM240_2066Putative glycero-phosphotransferase; CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerisation of the main chain of the teichoic acid by sequential trans [...]
CDM69225.1 protein networkhttps://string-db.org/network/1216932.CM240_2067Putative membrane protein; High confidence in function and specificity.
CDM69226.1 protein networkhttps://string-db.org/network/1216932.CM240_2068This family consists of several capsular polysaccharide proteins. Capsular polysaccharide (CPS) is a major virulence factor in Streptococcus pneumoniae; Family membership.
CDM69227.1 protein networkhttps://string-db.org/network/1216932.CM240_2069Glycerol-3-phosphate cytidylyltransferase; Provides activated glycerol phosphate for teichoic acid synthesis, via incorporation into both the linkage unit and the teichoic acid polymer by TagB an [...]
CDM69228.1 protein networkhttps://string-db.org/network/1216932.CM240_2070Glycosyl transferase, family 2; Diverse family, transferring sugar from UDP-glucose,UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol [...]
CDM69229.1 protein networkhttps://string-db.org/network/1216932.CM240_2071Putative acetyl transferase; A variety of bacterial transferases contain a repeat structure composed of tandem repeats of a [LIV]-G-X(4) hexapeptide, which, in the tertiary structure of LpxA (UDP [...]
CDM69230.1 protein networkhttps://string-db.org/network/1216932.CM240_2072Group 1 glycosyl transferase; Members of this family transfer activated sugars to a variety of substrates, including glycogen,Fructose-6-phosphate and lipopolysaccharides. Members of this family [...]
CDM69231.1 protein networkhttps://string-db.org/network/1216932.CM240_2073Glycosyltransferase; Mutations in this domain of P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, includ [...]
cpsE protein networkhttps://string-db.org/network/1216932.CM240_2074Putative Glycosyltransferase; This protein has a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways; High confidence in function a [...]
CDM69233.1 protein networkhttps://string-db.org/network/1216932.CM240_2075Capsular exopolysaccharide family; High confidence in function and specificity.
CDM69234.1 protein networkhttps://string-db.org/network/1216932.CM240_2076Capsular polysaccharide biosynthesis protein; Family membership.
ywqF protein networkhttps://string-db.org/network/1216932.CM240_2077UDP-glucose 6-dehydrogenase YwqF; Catalyzes the conversion of UDP-glucose into UDP-glucuronate, one of the precursors of teichuronic acid; High confidence in function and specificity.
CDM69236.1 protein networkhttps://string-db.org/network/1216932.CM240_2078Putative Glycosyltransferase; This Pfam family represents a conserved region from a number of different bacterial sugar transferases,involved in diverse biosynthesis pathways; High confidence in [...]
CDM69237.1 protein networkhttps://string-db.org/network/1216932.CM240_2079This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This family comprises the whole length of chain length determinant protein (or wzz protein) that confers a modal d [...]
rplY-2 protein networkhttps://string-db.org/network/1216932.CM240_208050S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
speA protein networkhttps://string-db.org/network/1216932.CM240_2081Arginine decarboxylase; High confidence in function and specificity.
CDM69240.1 protein networkhttps://string-db.org/network/1216932.CM240_2082Hypothetical protein; Family membership.
hypA protein networkhttps://string-db.org/network/1216932.CM240_2083Peptidase M16C associated domain protein; This domain appears in eukaryotes as well as bacteria and tends to be found near the C-terminus of the metalloprotease M16C; High confidence in function [...]
CDM69242.1 protein networkhttps://string-db.org/network/1216932.CM240_2084Hypothetical protein; High confidence in function and specificity.
mutS2 protein networkhttps://string-db.org/network/1216932.CM240_2085Endonuclease MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DN [...]
CDM69244.1 protein networkhttps://string-db.org/network/1216932.CM240_2086Protease; This is a group of peptidases belonging to MEROPS peptidase family U32 (clan U-). The type example is collagenase (gene prtC) from Porphyromonas gingivalis (Bacteroides gingivalis), whi [...]
CDM69245.1 protein networkhttps://string-db.org/network/1216932.CM240_2087Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of th [...]
CDM69246.1 protein networkhttps://string-db.org/network/1216932.CM240_2088Hypothetical protein.
CDM69247.1 protein networkhttps://string-db.org/network/1216932.CM240_2089Putative membrane protein.
pheT protein networkhttps://string-db.org/network/1216932.CM240_2090Phenylalanine-tRNA ligase beta subunit; henylalanine-tRNA synthetase (PheRS) is known to be among the most complex enzymes of the aaRS family. It is a heterodimeric class II enzyme of the (alphab [...]
pheS protein networkhttps://string-db.org/network/1216932.CM240_2091Phenylalanine-tRNA ligase alpha subunit; ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe); High confidence in function and specificity; Belongs to the class-II ami [...]
CDM69250.1 protein networkhttps://string-db.org/network/1216932.CM240_2092tRNA/rRNA methyltransferase SpoU; The spoU gene of Escherichia coli codes for a protein that shows strong similarities to previously characterised 2'-O-methyltransferases; High confidence in func [...]
ktrC protein networkhttps://string-db.org/network/1216932.CM240_2093Ktr system potassium uptake protein C; This domain is often found next to the PF02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified [...]
ntpJ protein networkhttps://string-db.org/network/1216932.CM240_2094V-type sodium ATP synthase subunit J; Mediates electrogenic transport of potassium as well as sodium. Acts probably as a potassium-sodium cotransporter. Major sodium reentry pathway at high pH va [...]
rplT protein networkhttps://string-db.org/network/1216932.CM240_209550S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
rpmI protein networkhttps://string-db.org/network/1216932.CM240_2096Ribosomal protein L35 is one of the proteins from the large subunit of the ribosome; Hypothetical protein; Belongs to the bacterial ribosomal protein bL35 family.
CDM69255.1 protein networkhttps://string-db.org/network/1216932.CM240_2097Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
thrS protein networkhttps://string-db.org/network/1216932.CM240_2098Threonine-tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end o [...]
CDM69257.1 protein networkhttps://string-db.org/network/1216932.CM240_2099Hypothetical protein; Family membership.
CDM69258.1 protein networkhttps://string-db.org/network/1216932.CM240_2100Hypothetical protein; High confidence in function and specificity.
CDM69259.1 protein networkhttps://string-db.org/network/1216932.CM240_2101Hypothetical protein; Frameshift; Family membership; Belongs to the peptidase S8 family.
CDM69261.1 protein networkhttps://string-db.org/network/1216932.CM240_2104Hypothetical protein; Frameshift; High confidence in function and specificity.
CDM69262.1 protein networkhttps://string-db.org/network/1216932.CM240_2105Hypothetical protein; High confidence in function and specificity.
hslO3 protein networkhttps://string-db.org/network/1216932.CM240_2106Heat shock protein 33 homolog; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in th [...]
CDM69264.1 protein networkhttps://string-db.org/network/1216932.CM240_2107S-adenosylmethionine-dependentmethyltransferase; High confidence in function and specificity.
CDM69265.1 protein networkhttps://string-db.org/network/1216932.CM240_2108Small, acid-soluble spore proteins (SASP or ASSP) are proteins bound to the spore DNA of bacteria of the genera Bacillus, Thermoactynomycetes, and Clostridium; Hypothetical protein.
CDM69266.1 protein networkhttps://string-db.org/network/1216932.CM240_2109Putative membrane protein.
appF1 protein networkhttps://string-db.org/network/1216932.CM240_2110Oligopeptide transport ATP-binding protein AppF; High confidence in function and specificity; Belongs to the ABC transporter superfamily.
appD protein networkhttps://string-db.org/network/1216932.CM240_2111Oligopeptide transport ATP-binding protein AppD; High confidence in function and specificity; Belongs to the ABC transporter superfamily.
CDM69269.1 protein networkhttps://string-db.org/network/1216932.CM240_2112Oligopeptide ABC transporter; Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two reciprocal [...]
appB protein networkhttps://string-db.org/network/1216932.CM240_2113This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic [...]
CDM69271.1 protein networkhttps://string-db.org/network/1216932.CM240_2114Oligopeptide-binding protein AppA; Bacterial high affinity transport systems are involved in active transport of solutes across the cytoplasmic membrane. The protein components of these traffic s [...]
oppA1 protein networkhttps://string-db.org/network/1216932.CM240_2115Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein; These homologue proteins do not play an integral role in the transport process per se, but probably serve as receptors to t [...]
oppA3 protein networkhttps://string-db.org/network/1216932.CM240_2116Oligopeptide-binding protein OppA; High confidence in function and specificity.
oppA5 protein networkhttps://string-db.org/network/1216932.CM240_2117Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein; These homologue proteins do not play an integral role in the transport process per se, but probably serve as receptors to t [...]
appF3 protein networkhttps://string-db.org/network/1216932.CM240_2118Oligopeptide transport ATP-binding protein AppF; High confidence in function and specificity; Belongs to the ABC transporter superfamily.
oppD protein networkhttps://string-db.org/network/1216932.CM240_2119Oligopeptide transport ATP-binding protein OppD; High confidence in function and specificity; Belongs to the ABC transporter superfamily.
oppC protein networkhttps://string-db.org/network/1216932.CM240_2120Oligopeptide transport system permease protein OppC; High confidence in function and specificity.
oppB protein networkhttps://string-db.org/network/1216932.CM240_2121Oligopeptide transport system permease protein OppB; High confidence in function and specificity.
dapA1 protein networkhttps://string-db.org/network/1216932.CM240_21224-hydroxy-tetrahydrodipicolinate synthase 1; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
dapB protein networkhttps://string-db.org/network/1216932.CM240_21234-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
CDM69281.1 protein networkhttps://string-db.org/network/1216932.CM240_2124Hypothetical protein.
CDM69282.1 protein networkhttps://string-db.org/network/1216932.CM240_2125Hypothetical protein; Family membership; Belongs to the sigma-70 factor family. ECF subfamily.
CDM69283.1 protein networkhttps://string-db.org/network/1216932.CM240_2126Hypothetical protein; Family membership.
CDM69284.1 protein networkhttps://string-db.org/network/1216932.CM240_21275-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H; High confidence in function and specificity.
CDM69285.1 protein networkhttps://string-db.org/network/1216932.CM240_2128Hypothetical protein.
ung protein networkhttps://string-db.org/network/1216932.CM240_2129Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
CDM69287.1 protein networkhttps://string-db.org/network/1216932.CM240_2130Methyl-accepting chemotaxis sensory transducer; Bacterial chemotactic-signal transducers are proteins that respond to changes in the concentration of attractants and repellents in the environment [...]
CDM69288.1 protein networkhttps://string-db.org/network/1216932.CM240_2131Methyl-accepting chemotaxis sensory transducer; Bacterial chemotactic-signal transducers are proteins that respond to changes in the concentration of attractants and repellents in the environment [...]
CDM69289.1 protein networkhttps://string-db.org/network/1216932.CM240_2132Methyl-accepting chemotaxis sensory transducer; Bacterial chemotactic-signal transducers are proteins that respond to changes in the concentration of attractants and repellents in the environment [...]
purD protein networkhttps://string-db.org/network/1216932.CM240_2133Phosphoribosylamine-glycine ligase; Phosphoribosylglycinamide synthetase (GARS) (phosphoribosylamine glycine ligase)catalyses the second step in the de novo biosynthesis of purine; High confidenc [...]
purH protein networkhttps://string-db.org/network/1216932.CM240_2134Bifunctional purine biosynthesis protein PurH; This is a family of bifunctional enzymes catalysing the last two steps in de novo purine biosynthesis; High confidence in function and specificity.
CDM69292.1 protein networkhttps://string-db.org/network/1216932.CM240_2135Hypothetical protein; Family membership.
purN protein networkhttps://string-db.org/network/1216932.CM240_2136Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylg [...]
purM protein networkhttps://string-db.org/network/1216932.CM240_2137Phosphoribosylformylglycinamidine cyclo-ligase; The purine biosynthetic pathway in procaryotes enlists eleven enzymes, six of which use ATP. Enzymes 5 and 6 of this pathway, formylglycinamide rib [...]
purF protein networkhttps://string-db.org/network/1216932.CM240_2138Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
purC protein networkhttps://string-db.org/network/1216932.CM240_2139Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) catalyzes the seventh step in the de novo purine biosynthetic pathway; the ATP-dependent conversion of 5'-phosphoribos [...]
purE protein networkhttps://string-db.org/network/1216932.CM240_2140N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
CDM69298.1 protein networkhttps://string-db.org/network/1216932.CM240_2141Hypothetical protein.
CDM69299.1 protein networkhttps://string-db.org/network/1216932.CM240_2142Phosphoribosylformylglycinamidine synthase, an enzyme that catalyzes the fourth step in the de novo biosynthesis of purines. In some species of bacteria and archaea, FGAM synthase II is composed [...]
CDM69300.1 protein networkhttps://string-db.org/network/1216932.CM240_2143The DegV protein family received its name based on sequence similarity to the DegV protein from Bacillus subtilis. All members of the DegV family are from bacteria,mostly Firmicutes. The function [...]
dapF protein networkhttps://string-db.org/network/1216932.CM240_2144Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
CDM69302.1 protein networkhttps://string-db.org/network/1216932.CM240_2145Oligoendopeptidase, pepF/M3 family; This domain is found to the N-terminus of the PF01432 domain in bacterial and archaeal proteins including Oligoendopeptidase F; High confidence in function and [...]
CDM69303.1 protein networkhttps://string-db.org/network/1216932.CM240_2146Putative membrane protein.
CDM69304.1 protein networkhttps://string-db.org/network/1216932.CM240_2147Deoxyadenosine kinase / Deoxyguanosine kinase; This family consists of various deoxynucleoside kinases cytidine, guanosine, adenosineand thymidine kinase(which also phosphorylates deoxyuridine an [...]
pfp protein networkhttps://string-db.org/network/1216932.CM240_2148Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like commo [...]
sudA protein networkhttps://string-db.org/network/1216932.CM240_2149Glutamate synthase (NADPH), homotetrameric; This protein is homologous to the small subunit of NADPH and NADH forms of glutamate synthase as found in eukaryotes and some bacteria. This protein is [...]
CDM69307.1 protein networkhttps://string-db.org/network/1216932.CM240_2150Ferredoxin-NADP(+) reductase subunit alpha; In chloroplasts and cyanobacteria the enzyme acts on plant-type [2Fe-2S] ferredoxins, but in other bacteria it can also reduce bacterial 2[4Fe-4S] ferr [...]
perR protein networkhttps://string-db.org/network/1216932.CM240_2151Transcriptional regulator PerR; Represses the expression of most of the genes involved in oxidative stress response, such as rbr3A-rbr3B,dfx, rd, nror, fprA1 and fprA2, coding for reverse rubrery [...]
CDM69309.1 protein networkhttps://string-db.org/network/1216932.CM240_2152Hypothetical protein; Family membership.
CDM69310.1 protein networkhttps://string-db.org/network/1216932.CM240_2153Hypothetical protein; Family membership.
CDM69311.1 protein networkhttps://string-db.org/network/1216932.CM240_2154Hypothetical protein.
CDM69312.1 protein networkhttps://string-db.org/network/1216932.CM240_2155Hypothetical protein.
engB protein networkhttps://string-db.org/network/1216932.CM240_2156Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. E [...]
lon protein networkhttps://string-db.org/network/1216932.CM240_2157Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular home [...]
clpX protein networkhttps://string-db.org/network/1216932.CM240_2158ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in th [...]
clpP3 protein networkhttps://string-db.org/network/1216932.CM240_2159ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
tig protein networkhttps://string-db.org/network/1216932.CM240_2160Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs t [...]
CDM69318.1 protein networkhttps://string-db.org/network/1216932.CM240_2161AP endonuclease family 2; These endonucleases play,a role in DNA repair. Cleave phosphodiester bonds at,apurinic or apyrimidinic sites; High confidence in function and specificity.
CDM69319.1 protein networkhttps://string-db.org/network/1216932.CM240_2162Putative membrane protein.
carB protein networkhttps://string-db.org/network/1216932.CM240_2164Carbamoyl-phosphate synthase (CPSase) catalyzes the ATP-dependent synthesis of carbamyl-phosphate from glutamine or ammonia and bicarbonate [1]. This important enzyme initiates both the urea cycl [...]
carA protein networkhttps://string-db.org/network/1216932.CM240_2165Glutamine-dependent carbamoyl-phosphate synthase (GD-CPSase); an enzyme involved in both arginine and pyrimidine biosynthesis and which catalyzes the ATP-dependent formation of carbamoyl phosphat [...]
pyrD protein networkhttps://string-db.org/network/1216932.CM240_2166Dihydroorotate dehydrogenase B (NAD(+)),catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
pyrK protein networkhttps://string-db.org/network/1216932.CM240_2167Dihydroorotate dehydrogenase B (NAD(+)),electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subun [...]
pyrF protein networkhttps://string-db.org/network/1216932.CM240_2168Orotidine 5'-phosphate decarboxylase (OMPdecase) catalyzes the last step in the de novo biosynthesis of pyrimidines, the decarboxylation of OMP into UMP. In higher eukaryotes OMPdecase is part, w [...]
pyrC protein networkhttps://string-db.org/network/1216932.CM240_2169Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
pyrB protein networkhttps://string-db.org/network/1216932.CM240_2170Aspartate carbamoyltransferase (ATCase) catalyzes the conversion of aspartate and carbamoyl phosphate to carbamoylaspartate, the second step in the de novo biosynthesis of pyrimidine nucleotides. [...]
CDM69328.1 protein networkhttps://string-db.org/network/1216932.CM240_2171Hypothetical protein; Family membership.
CDM69329.1 protein networkhttps://string-db.org/network/1216932.CM240_2185Hypothetical protein.
CDM69330.1 protein networkhttps://string-db.org/network/1216932.CM240_2187Putative phosphoesterase; Members of this largely uncharacterised family share a motif approximating DXH(X25)GDXXD(X25)GNHD as found in several phosphoesterases, including the nucleases SbcD and [...]
CDM69331.1 protein networkhttps://string-db.org/network/1216932.CM240_2188Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonica [...]
CDM69332.1 protein networkhttps://string-db.org/network/1216932.CM240_2189Hypothetical protein; High confidence in function and specificity.
CDM69333.1 protein networkhttps://string-db.org/network/1216932.CM240_2190Putative membrane protein.
CDM69334.1 protein networkhttps://string-db.org/network/1216932.CM240_2191Putative membrane protein; Family membership.
ligA2 protein networkhttps://string-db.org/network/1216932.CM240_2192DNA ligase 2; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sou [...]
pcrA protein networkhttps://string-db.org/network/1216932.CM240_2193ATP-dependent DNA helicase PcrA; Helicases have been classified in 5 superfamilies (SF1-SF5). All of the proteins bind ATP and,consequently,all of them carry the classical Walker A (phosphate-bin [...]
CDM69337.1 protein networkhttps://string-db.org/network/1216932.CM240_2194Putative protein; Family membership.
CDM69338.1 protein networkhttps://string-db.org/network/1216932.CM240_2195Pseudouridine synthases catalyse the isomerisation of uridine to pseudouridine (Psi) in a variety of RNA molecules, and may function as RNA chaperones. Pseudouridine is the most abundant modified [...]
CDM69339.1 protein networkhttps://string-db.org/network/1216932.CM240_2196Transglycosylase, SLT family; Bacterial lytic transglycosylases degrade murein via cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine, with the concomit [...]
CDM69340.1 protein networkhttps://string-db.org/network/1216932.CM240_2197Two component regulator three Y motif protein; This region is mostly found at the end of the beta propellers in a family of two component regulators; Family membership.
pulA1 protein networkhttps://string-db.org/network/1216932.CM240_2198Pullulanase; Pullulan is an unusual, industrially important polysaccharide in which short alpha-1,4 chains (maltotriose) are connected in alpha-1,6 linkages. Enzymes that cleave alpha-1,6 linkage [...]
pgi protein networkhttps://string-db.org/network/1216932.CM240_2199Glucose-6-phosphate isomerase (GPI) or phosphoglucose isomerase is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. PGI is involved in [...]
ilvE protein networkhttps://string-db.org/network/1216932.CM240_2200Putative branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
CDM69344.1 protein networkhttps://string-db.org/network/1216932.CM240_2201P-loop NTPases are characterised by two conserved sequence signatures, the Walker A The Walker A motif (the P-loop proper) and Walker B motifs which bind,respectively,the beta and gamma phosphate [...]
CDM69345.1 protein networkhttps://string-db.org/network/1216932.CM240_2202Hypothetical protein; Family membership.
CDM69346.1 protein networkhttps://string-db.org/network/1216932.CM240_2203Ser/Thr protein phosphatase family protein; Members of this family are part of the Calcineurin-like phosphoesterase superfamily; Family membership.
CDM69347.1 protein networkhttps://string-db.org/network/1216932.CM240_2204Hypothetical protein.
argC protein networkhttps://string-db.org/network/1216932.CM240_2205N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydroge [...]
argB protein networkhttps://string-db.org/network/1216932.CM240_2206Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
argD protein networkhttps://string-db.org/network/1216932.CM240_2207Acetylornithine aminotransferase which catalyzes the transfer of an amino group from acetylornithine to alpha-ketoglutarate, yielding N-acetyl-glutamic-5-semi-aldehyde and glutamic acid; High con [...]
CDM69351.2 protein networkhttps://string-db.org/network/1216932.CM240_2208Puative amidohydrolase; This model represents a subfamily of amidohydrolases which are a subset of those sequences detected by PF01546. Included within this group are hydrolases of hippurate (N-b [...]
yjbG protein networkhttps://string-db.org/network/1216932.CM240_2209Oligoendopeptidase F homolog; This domain is found to the N-terminus of the PF01432 domain in bacterial and archaeal proteins including Oligoendopeptidase F; High confidence in function and speci [...]
CDM69353.1 protein networkhttps://string-db.org/network/1216932.CM240_2210Hypothetical protein.
CDM69354.1 protein networkhttps://string-db.org/network/1216932.CM240_2211The ferric uptake regulator (FUR) family of proteins includes metal ion uptake regulator proteins. These are responsible for controlling the intracellular concentration of iron in many bacteria. [...]
CDM69355.1 protein networkhttps://string-db.org/network/1216932.CM240_2212Putative membrane protein; Probably functions as a manganese efflux pump.
CDM69356.1 protein networkhttps://string-db.org/network/1216932.CM240_2213Major facilitator superfamily MFS_1; Among the different families of transporter, only two occur ubiquitously in all classifications of organisms. These are the ATP-Binding Cassette (ABC) superfa [...]
CDM69357.1 protein networkhttps://string-db.org/network/1216932.CM240_2214N-Acyltransferase GCN5; The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions from bac [...]
CDM69358.1 protein networkhttps://string-db.org/network/1216932.CM240_2215HAD-superfamily hydrolase, subfamily IA,variant 3; The haloacid dehydrogenase (HAD) superfamily includes phosphatases, phosphonatases, P-type ATPases,beta-phosphoglucomutases, phosphomannomutases [...]
CDM69359.1 protein networkhttps://string-db.org/network/1216932.CM240_2216Beta-lactamase domain-containing protein; Apart from the beta-lactamases and metallo-beta-lactamases, a number of other proteins contain this domain. These proteins include thiolesterases, member [...]
CDM69360.1 protein networkhttps://string-db.org/network/1216932.CM240_2217This domain catalyses N-acetyltransferase reactions; High confidence in function and specificity.
CDM69361.1 protein networkhttps://string-db.org/network/1216932.CM240_2218Acetyltransferase, gnat family; The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions [...]
CDM69362.1 protein networkhttps://string-db.org/network/1216932.CM240_22193-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
CDM69363.1 protein networkhttps://string-db.org/network/1216932.CM240_2220Hypothetical protein.
CDM69364.1 protein networkhttps://string-db.org/network/1216932.CM240_2221Hypothetical protein; Family membership.
cotJC protein networkhttps://string-db.org/network/1216932.CM240_2222Protein CotJC; High confidence in function and specificity.
CDM69366.1 protein networkhttps://string-db.org/network/1216932.CM240_2223Nucleotidyltransferase domain-containing protein; Nucleotidyltransferases (EC 2.7.7) comprise a large enzyme family with diverse roles in polynucleotide synthesis and modification. This domain is [...]
CDM69367.1 protein networkhttps://string-db.org/network/1216932.CM240_2224Hypothetical protein.
CDM69368.1 protein networkhttps://string-db.org/network/1216932.CM240_2225LD-carboxypeptidase family protein; Muramoyl-tetrapeptide carboxypeptidase or LD-carboxypeptidase A hydrolyses a peptide bond between a di-basic amino acid and the C-terminal D-alanine in the tet [...]
CDM69369.1 protein networkhttps://string-db.org/network/1216932.CM240_2226Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylene [...]
CDM69370.1 protein networkhttps://string-db.org/network/1216932.CM240_2227The haloacid dehydrogenase (HAD) superfamily includes phosphatases, phosphonatases, P-type ATPases,beta-phosphoglucomutases, phosphomannomutases, and dehalogenases, which are involved in a variet [...]
CDM69371.1 protein networkhttps://string-db.org/network/1216932.CM240_2228The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions from bacterial antibiotic resist [...]
CDM69372.1 protein networkhttps://string-db.org/network/1216932.CM240_2229Transcriptional regulator, CarD family; CarD is a Myxococcus xanthus protein required for the activation of light-and starvation-inducible genes; Family membership.
CDM69373.1 protein networkhttps://string-db.org/network/1216932.CM240_2230Hypothetical protein.
CDM69374.1 protein networkhttps://string-db.org/network/1216932.CM240_2231This is a family of hydrolase enzymes. Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydr [...]
CDM69375.1 protein networkhttps://string-db.org/network/1216932.CM240_2232Aspartate/ornithine carbamoyltransferase,carbamoyl-P binding domain protein; High confidence in function and specificity.
CDM69376.1 protein networkhttps://string-db.org/network/1216932.CM240_2233Hypothetical protein; High confidence in function and specificity.
CDM69377.1 protein networkhttps://string-db.org/network/1216932.CM240_2234Hypothetical protein; Family membership.
CDM69378.1 protein networkhttps://string-db.org/network/1216932.CM240_2235Putative phosphatidylglycerophosphate synthase; All of these members have the ability to catalyse the displacement of CMP from a CDP-alcohol by a second alcohol with formation of a phosphodiester [...]
CDM69379.1 protein networkhttps://string-db.org/network/1216932.CM240_2236Hypothetical protein; Family membership.
mta protein networkhttps://string-db.org/network/1216932.CM240_2237HTH-type transcriptional activator mta; High confidence in function and specificity.
CDM69381.1 protein networkhttps://string-db.org/network/1216932.CM240_2238The Nudix family is a protein family of phosphohydrolases.Using water-mediated catalysis they break a phosphate bond in their substrate to create two products; High confidence in function and spe [...]
CDM69382.1 protein networkhttps://string-db.org/network/1216932.CM240_2239Putative membrane protein.
CDM69383.1 protein networkhttps://string-db.org/network/1216932.CM240_2240Hypothetical protein; High confidence in function and specificity.
CDM69384.1 protein networkhttps://string-db.org/network/1216932.CM240_2241Putative membrane protein.
CDM69385.1 protein networkhttps://string-db.org/network/1216932.CM240_2242Sodium/proline symporter; High confidence in function and specificity; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
CDM69386.1 protein networkhttps://string-db.org/network/1216932.CM240_2243Hypothetical protein; Family membership.
CDM69387.1 protein networkhttps://string-db.org/network/1216932.CM240_2244Putative phenazine biosynthesis PhzC/PhzF protein; PhzC/PhzF is involved in dimerisation of two 2,3-dihydro-3-oxo-anthranilic acid molecules to create PCA by P. fluorescens.This family also conta [...]
CDM69388.1 protein networkhttps://string-db.org/network/1216932.CM240_2245Putative membrane protein; High confidence in function and specificity.
CDM69389.1 protein networkhttps://string-db.org/network/1216932.CM240_2246Methyltransferase type 11; This family appears to be have methyltransferase activity; High confidence in function and specificity.
CDM69390.1 protein networkhttps://string-db.org/network/1216932.CM240_2247Hypothetical protein; Family membership.
cobB3 protein networkhttps://string-db.org/network/1216932.CM240_2248NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. [...]
CDM69393.1 protein networkhttps://string-db.org/network/1216932.CM240_2250Methyl-accepting chemotaxis protein; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs; Hypothetical protein.
CDM69394.1 protein networkhttps://string-db.org/network/1216932.CM240_2251Methyl-accepting chemotaxis sensory transducer; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs; Family membership.
CDM69395.1 protein networkhttps://string-db.org/network/1216932.CM240_2252Hypothetical protein; Framsehift; Family membership.
CDM69396.1 protein networkhttps://string-db.org/network/1216932.CM240_2254Hypothetical protein; High confidence in function and specificity.
CDM69397.1 protein networkhttps://string-db.org/network/1216932.CM240_2255The Peptidase M22 proteins are part of the HSP70-actin superfamily. The region represented here is an insert into the fold and is not found in the rest of the family (beyond the Peptidase M22 fam [...]
CDM69398.2 protein networkhttps://string-db.org/network/1216932.CM240_2256Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.
CDM69399.1 protein networkhttps://string-db.org/network/1216932.CM240_2257Putative membrane protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-trans [...]
ydcI protein networkhttps://string-db.org/network/1216932.CM240_2258This protein defines a novel family of prokaryotic transcriptional accessory factors; High confidence in function and specificity.
prfB protein networkhttps://string-db.org/network/1216932.CM240_2259Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
secA protein networkhttps://string-db.org/network/1216932.CM240_2260Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the [...]
hpf protein networkhttps://string-db.org/network/1216932.CM240_2261Ribosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present d [...]
CDM69404.1 protein networkhttps://string-db.org/network/1216932.CM240_2262Putative membrane protein.
CDM69405.1 protein networkhttps://string-db.org/network/1216932.CM240_2263ComF protein, homolog; This protein is found in species that do (Bacillus subtilis, Haemophilus influenzae) or do not (E. coli,Borrelia burgdorferi) have described systems for natural transformat [...]
CDM69406.1 protein networkhttps://string-db.org/network/1216932.CM240_2264Hypothetical protein.
recD2 protein networkhttps://string-db.org/network/1216932.CM240_2265Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase a [...]
metK5 protein networkhttps://string-db.org/network/1216932.CM240_2266S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formati [...]
CDM69409.1 protein networkhttps://string-db.org/network/1216932.CM240_2272This entry represents the PP-loop motif superfamily. The PP-loop motif appears to be a modified version of the P-loop of nucleotide binding domain that is involved in phosphate binding; High conf [...]
CDM69410.1 protein networkhttps://string-db.org/network/1216932.CM240_2273Sporulation protein YyaC; This family consists of several uncharacterised bacterial proteins which seem to be specific to the orders Clostridia and Bacillales. Family members are typically around [...]
mbl protein networkhttps://string-db.org/network/1216932.CM240_2274MreB-like protein; MreB is known to be a rod shape-determining protein in bacteria and goes to make up the bacterial cytoskeleton. Genes coding for MreB/Mbl are only found in elongated bacteria, [...]
CDM69412.1 protein networkhttps://string-db.org/network/1216932.CM240_2275This stage III sporulation protein is a small DNA-binding family that is essential for gene expression of the mother-cell compartment during sporulation. The domain is found in bacteria and virus [...]
CDM69413.1 protein networkhttps://string-db.org/network/1216932.CM240_2276Hypothetical protein; Family membership.
CDM69414.1 protein networkhttps://string-db.org/network/1216932.CM240_2277This domain is found in the stage II sporulation protein SpoIID. SpoIID is necessary for membrane migration as well as for some of the earlier steps in engulfment during bacterial endospore forma [...]
murA2 protein networkhttps://string-db.org/network/1216932.CM240_2278UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
CDM69416.1 protein networkhttps://string-db.org/network/1216932.CM240_2279Hypothetical protein.
atpC protein networkhttps://string-db.org/network/1216932.CM240_2280Putative ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.
atpD3 protein networkhttps://string-db.org/network/1216932.CM240_2281ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
atpG protein networkhttps://string-db.org/network/1216932.CM240_2282ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of [...]
atpA3 protein networkhttps://string-db.org/network/1216932.CM240_2283ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
atpH protein networkhttps://string-db.org/network/1216932.CM240_2284ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extra [...]
atpF-2 protein networkhttps://string-db.org/network/1216932.CM240_2285ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
atpE protein networkhttps://string-db.org/network/1216932.CM240_2286Putative membrane protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extram [...]
atpB3 protein networkhttps://string-db.org/network/1216932.CM240_2287ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.
CDM69425.1 protein networkhttps://string-db.org/network/1216932.CM240_2288Putative membrane protein.
thlA protein networkhttps://string-db.org/network/1216932.CM240_2289Acetoacetyl-CoA thiolase (also called thiolase II) is specific for the thiolysis of acetoacetyl-CoA and involved in biosynthetic pathways such as poly beta-hydroxybutyrate synthesis or steroid bi [...]
CDM69427.1 protein networkhttps://string-db.org/network/1216932.CM240_2290This family consists of UDP-N-acetylglucosamine 2-epimerasesthis enzyme catalyses the production of UDP-ManNAc from UDP-GlcNAc. Note that some of the enzymes is this family are bifunctional such [...]
CDM69428.1 protein networkhttps://string-db.org/network/1216932.CM240_2291Putative undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphatetransferase; Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is a bacterial enzyme responsible for the formation of the fi [...]
upp protein networkhttps://string-db.org/network/1216932.CM240_2292Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
CDM69430.1 protein networkhttps://string-db.org/network/1216932.CM240_2293Ribose 5-phosphate isomerase forms a homodimer and catalyses the interconversion of D-ribose 5-phosphate and D-ribulose 5-phosphate in the non-oxidative branch of the pentose phosphate pathway. T [...]
ywlC protein networkhttps://string-db.org/network/1216932.CM240_2294SUA5 protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
CDM69432.1 protein networkhttps://string-db.org/network/1216932.CM240_2295Zinc/iron permease; These ZIP zinc transporter proteins define a family of metal ion transporters that are found in plants,protozoa, fungi, invertebrates, and vertebrates,making it now possible t [...]
CDM69433.1 protein networkhttps://string-db.org/network/1216932.CM240_2296Hypothetical protein; Family membership.
prfA protein networkhttps://string-db.org/network/1216932.CM240_2297Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
prmC protein networkhttps://string-db.org/network/1216932.CM240_2298Protein-(Glutamine-N5) methyltransferase,release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally [...]
CDM69436.1 protein networkhttps://string-db.org/network/1216932.CM240_2299Putative membrane protein; High confidence in function and specificity.
tdk protein networkhttps://string-db.org/network/1216932.CM240_2300Thymidine kinase (TK) is an ubiquitous enzyme that catalyzes the ATP-dependent phosphorylation of thymidine. A comparison of TK sequences has shown [1,2,3] that there are two different families o [...]
rpmE protein networkhttps://string-db.org/network/1216932.CM240_230150S ribosomal protein L31; Binds the 23S rRNA.
rho protein networkhttps://string-db.org/network/1216932.CM240_2302Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
pyrG protein networkhttps://string-db.org/network/1216932.CM240_2303CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the fo [...]
CDM69441.1 protein networkhttps://string-db.org/network/1216932.CM240_2304Hypothetical protein.
CDM69442.1 protein networkhttps://string-db.org/network/1216932.CM240_2305Hypothetical protein; High confidence in function and specificity.
ddl5 protein networkhttps://string-db.org/network/1216932.CM240_2306D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
CDM69444.1 protein networkhttps://string-db.org/network/1216932.CM240_2307Monogalactosyldiacylglycerol synthase; This family represents a conserved region of approximately 180 residues within plant and bacterial monogalactosyldiacylglycerol (MGDG) synthase (. In Arabid [...]
CDM69445.1 protein networkhttps://string-db.org/network/1216932.CM240_2308SpoIIR is designated stage II sporulation protein R. A comparative genome analysis of all sequenced genomes of Firmicutes shows that the proteins are strictly conserved among the sub-set of endos [...]
CDM69446.1 protein networkhttps://string-db.org/network/1216932.CM240_2309Germination protein, Ger(X)C family; The GerAC protein of the Bacillus subtilis spore is required for the germination response to L-alanine. Members of this family are thought to be located in th [...]
CDM69447.2 protein networkhttps://string-db.org/network/1216932.CM240_2310Spore germination protein; Amino acid permeases are integral membrane proteins involved in the transport of amino acids into the cell. A number of such proteins have been found to be evolutionary [...]
gerA1 protein networkhttps://string-db.org/network/1216932.CM240_2311Spore germination protein GerA; Involved in the germination response to the combination of glucose, fructose, L-asparagine, and KCl; High confidence in function and specificity.
CDM69449.1 protein networkhttps://string-db.org/network/1216932.CM240_2312Putative membrane protein.
ispE protein networkhttps://string-db.org/network/1216932.CM240_23134-diphosphocytidyl-2-C-methyl-D- erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
CDM69451.1 protein networkhttps://string-db.org/network/1216932.CM240_2314The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding func [...]
CDM69452.1 protein networkhttps://string-db.org/network/1216932.CM240_2315Hypothetical protein.
CDM69453.1 protein networkhttps://string-db.org/network/1216932.CM240_2316Sporulation peptidase YabG; YabG is a protease involved in the proteolysis and maturation of SpoIVA and YrbA proteins, conserved with the cortex and/or coat assembly by Bacillus subtilis; High co [...]
CDM69454.1 protein networkhttps://string-db.org/network/1216932.CM240_2317Members of this entry include the spore coat proteins CotS and YtaA from Bacillus subtilis and, from other endospore-forming bacteria, homologues that are more closely related to these two than t [...]
CDM69455.1 protein networkhttps://string-db.org/network/1216932.CM240_2318Putative glycosyltransferase; The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the [...]
CDM69456.1 protein networkhttps://string-db.org/network/1216932.CM240_2319Spore coat protein; Members of this entry include the spore coat proteins CotS and YtaA from Bacillus subtilis and, from other endospore-forming bacteria, homologues that are more closely related [...]
CDM69457.1 protein networkhttps://string-db.org/network/1216932.CM240_2320Hypothetical protein; High confidence in function and specificity.
CDM69458.1 protein networkhttps://string-db.org/network/1216932.CM240_2321CotS family spore coat protein; The CotS family is more broadly distributed than YutH or YsxE, but still is not universal among spore-formers; High confidence in function and specificity.
CDM69459.1 protein networkhttps://string-db.org/network/1216932.CM240_2322Glycosyltransferase; The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the transfer [...]
CDM69460.1 protein networkhttps://string-db.org/network/1216932.CM240_2323Hypothetical protein; Family membership.
CDM69461.1 protein networkhttps://string-db.org/network/1216932.CM240_2324This domain is present in a variety of proteins that include, bacterial flavohemoprotein, mammalian NADH-cytochrome b5 reductase, eukaryotic NADPH-cytochrome P450 reductase, nitrate reductase fro [...]
gapN3 protein networkhttps://string-db.org/network/1216932.CM240_2325NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; High confidence in function and specificity; Belongs to the aldehyde dehydrogenase family.
CDM69463.1 protein networkhttps://string-db.org/network/1216932.CM240_2326Proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues [1,2,3]. The best studied of these proteins is the prokaryotic catabolite gene activator (also [...]
CDM69464.1 protein networkhttps://string-db.org/network/1216932.CM240_2327Mannose-1-phosphate guanylyltransferase; GTP + alpha-D-mannose 1-phosphate <=> diphosphate + GDP-mannose; High confidence in function and specificity.
CDM69465.1 protein networkhttps://string-db.org/network/1216932.CM240_2328Cation transport ATPase; Transmembrane ATPases are membrane-bound enzyme complexes/ion transporters that use ATP hydrolysis to drive the transport of protons across a membrane. Some transmembrane [...]
CDM69466.1 protein networkhttps://string-db.org/network/1216932.CM240_2329Cation transport ATPase; The P-type ATPases, also known as E1-E2 ATPases,are a large group of evolutionarily related ion and lipid pumps that are found in bacteria, archaea, and eukaryotes; High [...]
CDM69467.1 protein networkhttps://string-db.org/network/1216932.CM240_2330Hypothetical protein; High confidence in function and specificity.
CDM69468.1 protein networkhttps://string-db.org/network/1216932.CM240_2331Hypothetical protein; Family membership.
CDM69469.1 protein networkhttps://string-db.org/network/1216932.CM240_23323-phosphoglycerate dehydrogenase, a bacterial enzyme that catalyzes the oxidation of D-3-phosphoglycerate to 3-phosphohydroxypyruvate. This reaction is the first committed step in the 'phosphoryl [...]
CDM69470.1 protein networkhttps://string-db.org/network/1216932.CM240_2333The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions from bacterial antibiotic resist [...]
CDM69471.1 protein networkhttps://string-db.org/network/1216932.CM240_2334Hypothetical protein; Family membership.
CDM69473.1 protein networkhttps://string-db.org/network/1216932.CM240_2336Hypothetical protein.
copA protein networkhttps://string-db.org/network/1216932.CM240_2337Copper-exporting P-type ATPase A; This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to, which mainly transports the divalent copper ion; High confidence in f [...]
CDM69475.1 protein networkhttps://string-db.org/network/1216932.CM240_2338Hypothetical protein.
CDM69476.1 protein networkhttps://string-db.org/network/1216932.CM240_2339Methylpurine-DNA glycosylase is a base excision-repair protein. It is responsible for the hydrolysis of the deoxyribose N-glycosidic bond, excising 3-methyladenine and 3-methylguanine from damage [...]
CDM69477.1 protein networkhttps://string-db.org/network/1216932.CM240_2340ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM69478.1 protein networkhttps://string-db.org/network/1216932.CM240_2341ABC transporter permease; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as Escherichia coli LivH P08340 and LivM P22729 both of which [...]
CDM69479.1 protein networkhttps://string-db.org/network/1216932.CM240_2342Hypothetical protein; High confidence in function and specificity.
CDM69480.1 protein networkhttps://string-db.org/network/1216932.CM240_2343Hypothetical protein; High confidence in function and specificity.
CDM69481.1 protein networkhttps://string-db.org/network/1216932.CM240_2344Putative membrane protein.
GlyP protein networkhttps://string-db.org/network/1216932.CM240_2345Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural subst [...]
CDM69483.1 protein networkhttps://string-db.org/network/1216932.CM240_2346Hypothetical protein; Family membership.
CDM69484.1 protein networkhttps://string-db.org/network/1216932.CM240_2347Hypothetical protein; Family membership.
yeaC3 protein networkhttps://string-db.org/network/1216932.CM240_2348Putative protein YeaC; High confidence in function and specificity.
leuA protein networkhttps://string-db.org/network/1216932.CM240_23492-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isoprop [...]
CDM69487.1 protein networkhttps://string-db.org/network/1216932.CM240_2350Hypothetical protein; Family membership.
CDM69488.1 protein networkhttps://string-db.org/network/1216932.CM240_2351Hypothetical protein; Family membership.
CDM69489.1 protein networkhttps://string-db.org/network/1216932.CM240_2352Hypothetical protein; Family membership.
CDM69490.1 protein networkhttps://string-db.org/network/1216932.CM240_2353Sensor histidine kinase; The HAMP linker domain (domain present in Histidine kinases, Adenyl cyclases, Methyl-accepting proteins and Phosphatases) is an approximately 50-amino acid alpha-helical [...]
CDM69491.1 protein networkhttps://string-db.org/network/1216932.CM240_2354Transcriptional regulatory protein ResD; High confidence in function and specificity.
map-2 protein networkhttps://string-db.org/network/1216932.CM240_2355Putative methionine aminopeptidase A; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small [...]
CDM69493.1 protein networkhttps://string-db.org/network/1216932.CM240_2356Hypothetical protein; Frameshift; Family membership.
aroE protein networkhttps://string-db.org/network/1216932.CM240_2357Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshiki [...]
dnaK5 protein networkhttps://string-db.org/network/1216932.CM240_2358Molecular chaperone DnaK; Prokaryotic and eukaryotic organisms respond to heat shock or other environmental stress by the induction of the synthesis of proteins collectively known as heat-shock p [...]
CDM69496.1 protein networkhttps://string-db.org/network/1216932.CM240_2359All proteins belonging to the hsp70 family bind ATP. A variety of functions has been postulated for hsp70 proteins. It now appears that some hsp70 proteins play an important role in the transport [...]
CDM69497.1 protein networkhttps://string-db.org/network/1216932.CM240_2360Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the [...]
cls3 protein networkhttps://string-db.org/network/1216932.CM240_2361Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
CDM69499.1 protein networkhttps://string-db.org/network/1216932.CM240_2362Putative membrane protein; High confidence in function and specificity.
CDM69500.1 protein networkhttps://string-db.org/network/1216932.CM240_2363Carboxyl-terminal protease; This group of putative serine peptidases belong to the MEROPS peptidase family S41 (C-terminal processing peptidase family, clan SM). The members of this group include [...]
CDM69501.2 protein networkhttps://string-db.org/network/1216932.CM240_2364Cell division protein FtsX; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein f [...]
ftsE3 protein networkhttps://string-db.org/network/1216932.CM240_2365Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
CDM69503.1 protein networkhttps://string-db.org/network/1216932.CM240_2366Transketolase C-terminal section; Transketolase (TK) catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5-phosphate to an aldose receptor, such as ribose 5-phosphate, to f [...]
CDM69504.2 protein networkhttps://string-db.org/network/1216932.CM240_2367Putative transketolase N-terminal section; Transketolase (TK) catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5-phosphate to an aldose receptor, such as ribose 5-phosph [...]
CDM69505.1 protein networkhttps://string-db.org/network/1216932.CM240_2368PemK-like protein; Toxic component of a type II toxin-antitoxin (TA) system.
CDM69506.1 protein networkhttps://string-db.org/network/1216932.CM240_2369Hypothetical protein.
alr protein networkhttps://string-db.org/network/1216932.CM240_2370Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
CDM69508.1 protein networkhttps://string-db.org/network/1216932.CM240_2371Hypothetical protein; Family membership.
CDM69509.1 protein networkhttps://string-db.org/network/1216932.CM240_2372Hypothetical protein.
CDM69510.1 protein networkhttps://string-db.org/network/1216932.CM240_2373Putative membrane protein; Belongs to the UPF0761 family.
CDM69511.1 protein networkhttps://string-db.org/network/1216932.CM240_2374Hypothetical protein; Family membership.
CDM69512.1 protein networkhttps://string-db.org/network/1216932.CM240_2375Hypothetical protein.
CDM69513.1 protein networkhttps://string-db.org/network/1216932.CM240_2376Hsp70 chaperones help to fold many proteins. Hsp70 assisted folding involves repeated cycles of substrate binding and release. Hsp70 activity is ATP dependent. Hsp70 proteins are made up of two r [...]
CDM69514.1 protein networkhttps://string-db.org/network/1216932.CM240_2377Hypothetical protein; Family membership.
CDM69515.1 protein networkhttps://string-db.org/network/1216932.CM240_2378Hypothetical protein.
CDM69516.1 protein networkhttps://string-db.org/network/1216932.CM240_2379Thiamine-phosphate pyrophosphorylase, putative; Thiamine monophosphate synthase (TMP) (catalyses the substitution of the pyrophosphate of 2-methyl-4-amino-5-hydroxymethylpyrimidine pyrophosphate [...]
thiC protein networkhttps://string-db.org/network/1216932.CM240_2380Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methioni [...]
thiH protein networkhttps://string-db.org/network/1216932.CM240_2381Thiamine biosynthesis protein ThiH; Biotin synthase (BioB), catalyses the last step of the biotin biosynthetic pathway. The reaction consists in the introduction of a sulphur atom into dethiobiot [...]
thiG protein networkhttps://string-db.org/network/1216932.CM240_2382Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of th [...]
CDM69520.1 protein networkhttps://string-db.org/network/1216932.CM240_2383Members of the HesA/MoeB/ThiF family of proteins include a number of members encoded in the midst of thiamine biosynthetic operons. This mix of known and putative ThiF proteins shows a deep split [...]
CDM69521.1 protein networkhttps://string-db.org/network/1216932.CM240_2384Hypothetical protein.
CDM69522.1 protein networkhttps://string-db.org/network/1216932.CM240_2385Alkaline phosphatase (ALP, ALKP) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins,and alkaloids; High confidence in fu [...]
CDM69523.1 protein networkhttps://string-db.org/network/1216932.CM240_2386Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate a [...]
CDM69524.1 protein networkhttps://string-db.org/network/1216932.CM240_2387Putative membrane protein.
CDM69525.1 protein networkhttps://string-db.org/network/1216932.CM240_2388Formate/nitrite transporter; Proteins in this entry belong to the Formate-Nitrite Transporter (FNT) family (TC 2.A.44). The prokaryotic proteins of the FNT family probably function in the transpo [...]
CDM69526.1 protein networkhttps://string-db.org/network/1216932.CM240_2389Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose,UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol [...]
CDM69527.1 protein networkhttps://string-db.org/network/1216932.CM240_2390The PnuC protein of Escherichia coli is membrane protein responsible for nicotinamide mononucleotide transport, subject to regulation by interaction with the NadR (also called NadI) protein. The [...]
CDM69528.1 protein networkhttps://string-db.org/network/1216932.CM240_2391Hypothetical protein; Family membership.
CDM69529.1 protein networkhttps://string-db.org/network/1216932.CM240_2392Family 2 glycosyl transferase; Diverse family, transferring sugar from UDP-glucose,UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol [...]
CDM69530.1 protein networkhttps://string-db.org/network/1216932.CM240_2393Undecaprenyl-phosphate glucose phosphotransferase; Sugar transferases involved in lipopolysaccharide synthesis; High confidence in function and specificity.
CDM69531.1 protein networkhttps://string-db.org/network/1216932.CM240_2394Glycosyl transferase 2 family protein; The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes cata [...]
CDM69532.1 protein networkhttps://string-db.org/network/1216932.CM240_2395Hypothetical protein; Family membership.
CDM69533.1 protein networkhttps://string-db.org/network/1216932.CM240_2396Hypothetical protein; Family membership.
CDM69534.1 protein networkhttps://string-db.org/network/1216932.CM240_2397Putative family 2 glycosyl transferase; The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes cat [...]
rfbB1 protein networkhttps://string-db.org/network/1216932.CM240_2398O-antigen export system ATP-binding protein RfbB; High confidence in function and specificity.
CDM69536.1 protein networkhttps://string-db.org/network/1216932.CM240_2399ABC-2 type transporter; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological import and export systems. ABC transp [...]
rmlC protein networkhttps://string-db.org/network/1216932.CM240_2400dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehy [...]
rfbB3 protein networkhttps://string-db.org/network/1216932.CM240_2401dTDP-glucose 4,6-dehydratase; Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction; High conf [...]
rmlA protein networkhttps://string-db.org/network/1216932.CM240_2402Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymid [...]
glmM protein networkhttps://string-db.org/network/1216932.CM240_2403Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
buk protein networkhttps://string-db.org/network/1216932.CM240_2404Butyrate kinase (gene buk). This enzyme is involved in the interconversion of butyrate and butyryl-CoA via the butyryl phosphate intermediate. Butyrate kinase is involved in the acidogenic phase [...]
ptb protein networkhttps://string-db.org/network/1216932.CM240_2405Phosphate butyryltransferase; Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate; High confidence in function and specificity.
CDM69543.1 protein networkhttps://string-db.org/network/1216932.CM240_2406Putative protein Cbei_0202; High confidence in function and specificity.
CDM69544.1 protein networkhttps://string-db.org/network/1216932.CM240_2407Putative membrane protein.
dacA protein networkhttps://string-db.org/network/1216932.CM240_2408Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
CDM69546.1 protein networkhttps://string-db.org/network/1216932.CM240_2409Putative Spore-cortex-lytic enzyme; These enzymes have been implicated in cell wall hydrolysis, most extensively in Bacillus subtilis. For instance P50739 is expressed during sporulation as an in [...]
CDM69547.1 protein networkhttps://string-db.org/network/1216932.CM240_2410Hypothetical protein; Family membership.
dut protein networkhttps://string-db.org/network/1216932.CM240_2411Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intrace [...]
ptsI protein networkhttps://string-db.org/network/1216932.CM240_2412Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate ac [...]
CDM69550.1 protein networkhttps://string-db.org/network/1216932.CM240_2413Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; High confidence in function and specificity.
CDM69551.1 protein networkhttps://string-db.org/network/1216932.CM240_2414N-acetylmuramoyl-L-alanine amidase is an enzyme that catalyzes a chemical reaction that cleaves the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopept [...]
CDM69552.1 protein networkhttps://string-db.org/network/1216932.CM240_2415This family consists of sodium-dependent phosphate transport proteins of the solute carrier family SLC34A. It includes mammalian type II renal Na+/Pi-cotransporters and other proteins from lower [...]
rpsI protein networkhttps://string-db.org/network/1216932.CM240_2416Ribosomal protein S9 is one of the proteins from the small ribosomal subunit; High confidence in function and specificity; Belongs to the universal ribosomal protein uS9 family.
rplM protein networkhttps://string-db.org/network/1216932.CM240_241750S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
truA2 protein networkhttps://string-db.org/network/1216932.CM240_2418tRNA pseudouridine synthase A 2; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
ecfT protein networkhttps://string-db.org/network/1216932.CM240_2419Energy-coupling factor transporter transmembrane protein EcfT; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF tra [...]
ecfA2 protein networkhttps://string-db.org/network/1216932.CM240_2420Energy-coupling factor transporter ATP-binding protein EcfA 2; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF [...]
ecfA1 protein networkhttps://string-db.org/network/1216932.CM240_2421Energy-coupling factor transporter ATP-binding protein EcfA1; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF [...]
rplQ protein networkhttps://string-db.org/network/1216932.CM240_2422Ribosomal protein L17 is one of the proteins from the large ribosomal subunit; High confidence in function and specificity.
rpoA protein networkhttps://string-db.org/network/1216932.CM240_2423DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpsD1 protein networkhttps://string-db.org/network/1216932.CM240_242430S ribosomal protein S4 A; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpsK protein networkhttps://string-db.org/network/1216932.CM240_242530S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsM protein networkhttps://string-db.org/network/1216932.CM240_242630S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpmJ protein networkhttps://string-db.org/network/1216932.CM240_2427Ribosomal protein L36 is the smallest protein from the large subunit of the prokaryotic ribosome; Hypothetical protein; Belongs to the bacterial ribosomal protein bL36 family.
infA protein networkhttps://string-db.org/network/1216932.CM240_2428Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
CDM69566.1 protein networkhttps://string-db.org/network/1216932.CM240_2429Hypothetical protein.
map protein networkhttps://string-db.org/network/1216932.CM240_2430Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
adk protein networkhttps://string-db.org/network/1216932.CM240_2431Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
secY protein networkhttps://string-db.org/network/1216932.CM240_2432Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at t [...]
rplO protein networkhttps://string-db.org/network/1216932.CM240_243350S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
rpmD protein networkhttps://string-db.org/network/1216932.CM240_2434Part of the 50S ribosomal subunit; Hypothetical protein.
rpsE protein networkhttps://string-db.org/network/1216932.CM240_243530S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 fam [...]
rplR protein networkhttps://string-db.org/network/1216932.CM240_2436Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
rplF protein networkhttps://string-db.org/network/1216932.CM240_243750S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rpsH protein networkhttps://string-db.org/network/1216932.CM240_243830S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to [...]
rpsZ protein networkhttps://string-db.org/network/1216932.CM240_243930S ribosomal protein S14 type Z; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
rplE protein networkhttps://string-db.org/network/1216932.CM240_244050S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rplX protein networkhttps://string-db.org/network/1216932.CM240_244150S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplN protein networkhttps://string-db.org/network/1216932.CM240_244250S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rpsQ protein networkhttps://string-db.org/network/1216932.CM240_244330S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rpmC protein networkhttps://string-db.org/network/1216932.CM240_244450S ribosomal protein L29; About 2/3 of the mass of the ribosome consists of RNA and 1/3 of protein. The proteins are named in accordance with the subunit of the ribosome which they belong to -th [...]
rplP protein networkhttps://string-db.org/network/1216932.CM240_244550S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsC protein networkhttps://string-db.org/network/1216932.CM240_244630S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplV protein networkhttps://string-db.org/network/1216932.CM240_244750S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wal [...]
rpsS protein networkhttps://string-db.org/network/1216932.CM240_244830S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplB protein networkhttps://string-db.org/network/1216932.CM240_244950S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rplW protein networkhttps://string-db.org/network/1216932.CM240_245050S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplD protein networkhttps://string-db.org/network/1216932.CM240_245150S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
rplC protein networkhttps://string-db.org/network/1216932.CM240_245250S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal rib [...]
rpsJ protein networkhttps://string-db.org/network/1216932.CM240_2453Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
tuf1-1 protein networkhttps://string-db.org/network/1216932.CM240_2454Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
fusA protein networkhttps://string-db.org/network/1216932.CM240_2455Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
rpsG protein networkhttps://string-db.org/network/1216932.CM240_245630S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
rpsL protein networkhttps://string-db.org/network/1216932.CM240_245730S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S an [...]
CDM69595.1 protein networkhttps://string-db.org/network/1216932.CM240_2458Putative ribosomal protein L7Ae-like; About 2/3 of the mass of the ribosome consists of RNA and 1/3 of protein. The proteins are named in accordance with the subunit of the ribosome which they be [...]
rpoC protein networkhttps://string-db.org/network/1216932.CM240_2459DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/1216932.CM240_2460DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
licT protein networkhttps://string-db.org/network/1216932.CM240_2461Transcription antiterminator LicT; High confidence in function and specificity.
rplL protein networkhttps://string-db.org/network/1216932.CM240_246250S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the ba [...]
rplJ protein networkhttps://string-db.org/network/1216932.CM240_246350S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
rplA protein networkhttps://string-db.org/network/1216932.CM240_246450S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/1216932.CM240_246550S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/1216932.CM240_2466Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.
secE protein networkhttps://string-db.org/network/1216932.CM240_2467Putative membrane protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
tuf1-2 protein networkhttps://string-db.org/network/1216932.CM240_2468Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
sigH protein networkhttps://string-db.org/network/1216932.CM240_2470RNA polymerase sigma-H factor; High confidence in function and specificity; Belongs to the sigma-70 factor family.
CDM69607.1 protein networkhttps://string-db.org/network/1216932.CM240_2471Hypothetical protein; High confidence in function and specificity.
yacO protein networkhttps://string-db.org/network/1216932.CM240_2472The TrmH family of RNA methyltransferases are involved in rRNA base modification; High confidence in function and specificity; Belongs to the class IV-like SAM-binding methyltransferase superfami [...]
mrnC protein networkhttps://string-db.org/network/1216932.CM240_2473Ribonuclease III; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 3 [...]
cysS protein networkhttps://string-db.org/network/1216932.CM240_2474Cysteine-tRNA ligase (also known as Cysteinyl-tRNA synthetase) is an alpha monomer and belongs to class Ia. It is highly specific despite not possessing the amino acid editing activity characteri [...]
ispD protein networkhttps://string-db.org/network/1216932.CM240_24752-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
yacL protein networkhttps://string-db.org/network/1216932.CM240_2476Putative PIN and TRAM-domain containing protein YacL; The TRAM domain can be found alone or in association with other domains, such as the catalytic biotin/lipoate synthase-like domain, the RNA m [...]
CDM69613.1 protein networkhttps://string-db.org/network/1216932.CM240_2477Hypothetical protein; High confidence in function and specificity.
disA protein networkhttps://string-db.org/network/1216932.CM240_2478DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule tha [...]
radA protein networkhttps://string-db.org/network/1216932.CM240_2479DNA repair protein RadA homolog; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated [...]
clpB3 protein networkhttps://string-db.org/network/1216932.CM240_2480Chaperone protein ClpB; This family belongs to the AAA+ (ATPase associated with diverse cellular activities) superfamily. Most of these proteins of this family (ClpA, ClpC, ClpD,ClpE,ClpX,HslU) a [...]
CDM69617.1 protein networkhttps://string-db.org/network/1216932.CM240_2481ATP:guanido phosphotransferases are a family of structurally and functionally related enzymes that reversibly catalyse the transfer of phosphate between ATP and various phosphogens; High confiden [...]
CDM69618.1 protein networkhttps://string-db.org/network/1216932.CM240_2482Hypothetical protein; High confidence in function and specificity.
CDM69619.1 protein networkhttps://string-db.org/network/1216932.CM240_2483Phosphoglycerate mutase (PGAM) and bisphosphoglycerate mutase (BPGM) are structurally related enzymes which catalyze reactions involving the transfer of phospho groups between the three carbon at [...]
CDM69620.1 protein networkhttps://string-db.org/network/1216932.CM240_2484Hypothetical protein.
CDM69621.1 protein networkhttps://string-db.org/network/1216932.CM240_2485Hypothetical protein; Family membership.
CDM69622.1 protein networkhttps://string-db.org/network/1216932.CM240_2486Putative membrane protein; Family membership.
CDM69623.1 protein networkhttps://string-db.org/network/1216932.CM240_2487ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM69624.1 protein networkhttps://string-db.org/network/1216932.CM240_2488Sensor signal transduction histidine kinase; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine [...]
CDM69625.1 protein networkhttps://string-db.org/network/1216932.CM240_2489Two component transcriptional regulator, winged helix family; Two-component signal transduction systems enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, an [...]
CDM69626.1 protein networkhttps://string-db.org/network/1216932.CM240_2494Metal-dependent phosphohydrolase HD sub domain; HD domain is a conserved protein domain. It is found in a superfamily of enzymes with a predicted or known phosphohydrolase activity. These enzymes [...]
murD protein networkhttps://string-db.org/network/1216932.CM240_2497UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF f [...]
glyQS protein networkhttps://string-db.org/network/1216932.CM240_2498Glycine-tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
yesW protein networkhttps://string-db.org/network/1216932.CM240_2499Rhamnogalacturonan endolyase YesW; High confidence in function and specificity.
CDM69630.1 protein networkhttps://string-db.org/network/1216932.CM240_2501Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS [...]
CDM69631.1 protein networkhttps://string-db.org/network/1216932.CM240_2502Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS [...]
CDM69632.1 protein networkhttps://string-db.org/network/1216932.CM240_2503VanW family protein; Family members include vancomycin resistance protein W (VanW). Genes encoding members of this family have been found in vancomycin resistance gene clusters vanB and vanG. The [...]
dacF protein networkhttps://string-db.org/network/1216932.CM240_2504D-alanyl-D-alanine carboxypeptidase; High confidence in function and specificity.
lysS protein networkhttps://string-db.org/network/1216932.CM240_2505Lysine-tRNA ligase; Aminoacyl-tRNA synthetases are a group of enzymes which activate amino acids and transfer them to specific tRNA molecules as the first step in protein biosynthesis. In prokary [...]
greA protein networkhttps://string-db.org/network/1216932.CM240_2506Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
dus1 protein networkhttps://string-db.org/network/1216932.CM240_2507Putative tRNA-dihydrouridine synthase 1; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target [...]
coaX protein networkhttps://string-db.org/network/1216932.CM240_2508Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
fhs protein networkhttps://string-db.org/network/1216932.CM240_2509Formate-tetrahydrofolate ligase (EC) (formyltetrahydrofolate synthetase) (FTHFS) is one of the enzymes participating in the transfer of one-carbon units,an essential element of various biosynthet [...]
ftsH5 protein networkhttps://string-db.org/network/1216932.CM240_2510ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral memb [...]
CDM69640.1 protein networkhttps://string-db.org/network/1216932.CM240_2511Phosphoribosyltransferases (PRT) are enzymes that catalyze the synthesis of beta-n-5'-monophosphates from phosphoribosylpyrophosphate (PRPP) and an enzyme specific amine. A number of PRT's are in [...]
tilS protein networkhttps://string-db.org/network/1216932.CM240_2512tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is c [...]
CDM69642.1 protein networkhttps://string-db.org/network/1216932.CM240_2513This family contains a number of bacterial stage II sporulation E proteins (. These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic an [...]
CDM69643.1 protein networkhttps://string-db.org/network/1216932.CM240_2518Hypothetical protein; High confidence in function and specificity.
CDM69644.1 protein networkhttps://string-db.org/network/1216932.CM240_2519Hypothetical protein.
CDM69645.1 protein networkhttps://string-db.org/network/1216932.CM240_2520Putative membrane protein.
CDM69646.1 protein networkhttps://string-db.org/network/1216932.CM240_2521Hypothetical protein.
CDM69647.1 protein networkhttps://string-db.org/network/1216932.CM240_2522The S4 domain typically occurs in a single copy at various positions in different proteins. The S4 domain can be found alone as in several small bacterial proteins (e.g. YabO from B. subtilis and [...]
CDM69648.1 protein networkhttps://string-db.org/network/1216932.CM240_2523DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
YabN protein networkhttps://string-db.org/network/1216932.CM240_2524MazG family protein; This domain is about 100 amino acid residues in length. It is found in the MazG protein from E. coli. It contains four conserved negatively charged residues that probably for [...]
CDM69650.1 protein networkhttps://string-db.org/network/1216932.CM240_2525Stage V sporulation protein B; Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of t [...]
spoVT protein networkhttps://string-db.org/network/1216932.CM240_2526Members of this protein family are stage V sporulation protein T, a protein of the sporulation/germination program in Bacillus subtilis and related species. The amino-terminal 50 amino acids are [...]
CDM69652.1 protein networkhttps://string-db.org/network/1216932.CM240_2527Putative membrane protein.
mfd protein networkhttps://string-db.org/network/1216932.CM240_2528Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated tr [...]
pth protein networkhttps://string-db.org/network/1216932.CM240_2529Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
CDM69655.1 protein networkhttps://string-db.org/network/1216932.CM240_2530Putative membrane protein.
CDM69656.1 protein networkhttps://string-db.org/network/1216932.CM240_2531Sensory transduction histidine kinase; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine prote [...]
srrA protein networkhttps://string-db.org/network/1216932.CM240_2532Member of the two-component regulatory system SrrA/SrrB, which is involved in the global regulation of staphylococcal virulence factors in response to environmental oxygen levels. SrrA binds to t [...]
panD protein networkhttps://string-db.org/network/1216932.CM240_2533Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
panC protein networkhttps://string-db.org/network/1216932.CM240_2534Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
panB protein networkhttps://string-db.org/network/1216932.CM240_25353-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to f [...]
CDM69661.1 protein networkhttps://string-db.org/network/1216932.CM240_2536Hypothetical protein; High confidence in function and specificity.
prs protein networkhttps://string-db.org/network/1216932.CM240_2537Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
glmU protein networkhttps://string-db.org/network/1216932.CM240_2538Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer [...]
spoVG protein networkhttps://string-db.org/network/1216932.CM240_2539Putative septation protein SpoVG; Could be involved in septation.
purR protein networkhttps://string-db.org/network/1216932.CM240_2540Pur operon repressor; High confidence in function and specificity.
murC protein networkhttps://string-db.org/network/1216932.CM240_2541UDP-N-acetylmuramate-L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
CDM69667.1 protein networkhttps://string-db.org/network/1216932.CM240_2543Chloride channels (CLCs) constitute an evolutionarily well-conserved family of voltage-gated channels that are structurally unrelated to the other known voltage-gated channels. They are found in [...]
CDM69668.1 protein networkhttps://string-db.org/network/1216932.CM240_2544Hypothetical protein.
CDM69669.1 protein networkhttps://string-db.org/network/1216932.CM240_2545Radical SAM domain-containing protein; This entry represents a family of uncharacterised protein of about 400 amino acids in length that contains a radical SAM domain in the N-terminal half. Memb [...]
CDM69670.1 protein networkhttps://string-db.org/network/1216932.CM240_2546Hypothetical protein; High confidence in function and specificity.
CDM69671.1 protein networkhttps://string-db.org/network/1216932.CM240_2547Hypothetical protein; Family membership.
CDM69672.1 protein networkhttps://string-db.org/network/1216932.CM240_2548MATE efflux family protein; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range of cati [...]
hisK protein networkhttps://string-db.org/network/1216932.CM240_2549Histidinol-phosphatase; This entry represents the histidinol phosphate phosphatase, HisJ of Bacillus subtilis, and related proteins from a number of species within a larger family of phosphatases [...]
CDM69674.1 protein networkhttps://string-db.org/network/1216932.CM240_2550PHP domain protein; The PHP (Polymerase and Histidinol Phosphatase) domain is a putative phosphoesterase domain; High confidence in function and specificity.
CDM69675.1 protein networkhttps://string-db.org/network/1216932.CM240_2551Hypothetical protein.
CDM69676.1 protein networkhttps://string-db.org/network/1216932.CM240_2552Hypothetical protein.
CDM69677.1 protein networkhttps://string-db.org/network/1216932.CM240_2553Hypothetical protein; Family membership.
treR protein networkhttps://string-db.org/network/1216932.CM240_2554Trehalose operon transcriptional repressor; High confidence in function and specificity.
treA protein networkhttps://string-db.org/network/1216932.CM240_2555Trehalose-6-phosphate hydrolase; Trehalose is a glucose disaccharide that serves in many biological systems as a compatible solute for protection against hyperosmotic and thermal stress. This fam [...]
treB protein networkhttps://string-db.org/network/1216932.CM240_2556PTS system trehalose-specific EIIBC component; High confidence in function and specificity.
CDM69681.1 protein networkhttps://string-db.org/network/1216932.CM240_2557Hypothetical protein.
CDM69682.1 protein networkhttps://string-db.org/network/1216932.CM240_2558Hypothetical protein; Family membership.
yfmM protein networkhttps://string-db.org/network/1216932.CM240_2559ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
rlmI protein networkhttps://string-db.org/network/1216932.CM240_2560Ribosomal RNA large subunit methyltransferase I; Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA; High confidence in function and specificity.
CDM69685.1 protein networkhttps://string-db.org/network/1216932.CM240_2561The mutS family of proteins is named after the Salmonella typhimurium MutS protein involved in mismatch repair; other members of the family included the eukaryotic MSH 1,2,3, 4,5 and 6 proteins. [...]
CDM69686.1 protein networkhttps://string-db.org/network/1216932.CM240_2562Putative Galactose-1-phosphate uridylyltransferase; Galactose-1-phosphate uridyl transferase(GalT) catalyses the transfer of an uridyldiphosphate group on galactose (or glucose) 1-phosphate. Duri [...]
CDM69687.1 protein networkhttps://string-db.org/network/1216932.CM240_2563Hypothetical protein.
comB protein networkhttps://string-db.org/network/1216932.CM240_2564Putative 2-phosphosulfolactate phosphatase; Thought to catalyse 2-phosphosulpholactate = sulpholactate + phosphate. probable magnesium cofactor. Involved in the second step of coenzyme M biosynth [...]
ytqA protein networkhttps://string-db.org/network/1216932.CM240_2565Radical SAM proteins catalyse diverse reactions,including unusual methylations,isomerisation,sulphur insertion, ring formation, anaerobic oxidation and protein radical formation; High confidence [...]
CDM69690.1 protein networkhttps://string-db.org/network/1216932.CM240_2566Hypothetical protein; Family membership.
CDM69691.1 protein networkhttps://string-db.org/network/1216932.CM240_2567Putative membrane protein; High confidence in function and specificity.
CDM69692.1 protein networkhttps://string-db.org/network/1216932.CM240_2568Hypothetical protein; High confidence in function and specificity.
CDM69693.1 protein networkhttps://string-db.org/network/1216932.CM240_2569Subtilisin like protease; Subtilases [1,2] are an extensive family of serine proteases whose catalytic activity is provided by a charge relay system; High confidence in function and specificity; [...]
CDM69694.1 protein networkhttps://string-db.org/network/1216932.CM240_2570Putative protein; This domain is functionally uncharacterised. This domain is found in bacteria. This presumed domain is about 170 amino acids in length. The domain appears to be related to the G [...]
murI protein networkhttps://string-db.org/network/1216932.CM240_2571Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
CDM69696.1 protein networkhttps://string-db.org/network/1216932.CM240_2572Hypothetical protein.
CDM69697.1 protein networkhttps://string-db.org/network/1216932.CM240_2573Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PP [...]
CDM69698.1 protein networkhttps://string-db.org/network/1216932.CM240_2574Hypothetical protein.
CDM69699.1 protein networkhttps://string-db.org/network/1216932.CM240_2575DNA-binding protein; The cro/C1-type HTH domain is a DNA-binding,helix-turn-helix (HTH) domain of about 50-60 residues present in transcriptional regulators. The domain is named after the transcr [...]
glgC1 protein networkhttps://string-db.org/network/1216932.CM240_2576Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between AT [...]
glgC3 protein networkhttps://string-db.org/network/1216932.CM240_2577Glucose-1-phosphate adenylyltransferase, GlgD subunit; This family is GlgD, an apparent regulatory protein that appears in an alpha2/beta2 heterotetramer with GlgC (glucose-1-phosphate adenylyltr [...]
glgA protein networkhttps://string-db.org/network/1216932.CM240_2578Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CDM69703.1 protein networkhttps://string-db.org/network/1216932.CM240_2579Hypothetical protein; Family membership.
CDM69704.1 protein networkhttps://string-db.org/network/1216932.CM240_2580Hypothetical protein; Family membership.
nox protein networkhttps://string-db.org/network/1216932.CM240_2581NADH oxidase; High confidence in function and specificity.
CDM69706.1 protein networkhttps://string-db.org/network/1216932.CM240_2582Putative hydrolase; High confidence in function and specificity.
asnS protein networkhttps://string-db.org/network/1216932.CM240_2583Asparagine-tRNA ligase; Aminoacyl-tRNA synthetases [1] are a group of enzymes which activate amino acids and transfer them to specific tRNA molecules as the first step in protein biosynthesis. In [...]
ispF protein networkhttps://string-db.org/network/1216932.CM240_25842-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
CDM69709.1 protein networkhttps://string-db.org/network/1216932.CM240_2585Hypothetical protein.
uvdE protein networkhttps://string-db.org/network/1216932.CM240_2586UV damage endonuclease UvdE; Component in a DNA repair pathway. Removal of UV LIGHT damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion [...]
CDM69711.1 protein networkhttps://string-db.org/network/1216932.CM240_2587Hypothetical protein; Family membership.
YpsC protein networkhttps://string-db.org/network/1216932.CM240_2588Putative RNA methyltransferase; This domain is probably a methylase. It is associated with the THUMP domain that also occurs with RNA modification domains; High confidence in function and specifi [...]
CDM69713.1 protein networkhttps://string-db.org/network/1216932.CM240_2589Putative membrane protein.
CDM69714.1 protein networkhttps://string-db.org/network/1216932.CM240_2590Hypothetical protein.
CDM69715.1 protein networkhttps://string-db.org/network/1216932.CM240_2591araC, the arabinose operon regulatory protein,which activates the transcription of the araBAD genes; High confidence in function and specificity.
CDM69716.1 protein networkhttps://string-db.org/network/1216932.CM240_2592MATE efflux family protein; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range of cati [...]
CDM69717.1 protein networkhttps://string-db.org/network/1216932.CM240_2593Putative membrane protein; Family membership.
CDM69718.1 protein networkhttps://string-db.org/network/1216932.CM240_2594Hypothetical protein; Frameshift; Family membership.
proC protein networkhttps://string-db.org/network/1216932.CM240_2595Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
proB protein networkhttps://string-db.org/network/1216932.CM240_2596Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
CDM69721.1 protein networkhttps://string-db.org/network/1216932.CM240_2597PTS system, glucose subfamily, IIA subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS) [1,2] is a major carbohydrate transport system in bacteria. The PTS catalyzes t [...]
nadA protein networkhttps://string-db.org/network/1216932.CM240_2598Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
nadB protein networkhttps://string-db.org/network/1216932.CM240_2599L-aspartate oxidase; High confidence in function and specificity.
nadC protein networkhttps://string-db.org/network/1216932.CM240_2600Putative nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA); High confidence in function and specificity; Belongs to the NadC/ModD family.
CDM69725.1 protein networkhttps://string-db.org/network/1216932.CM240_2601Hypothetical protein; High confidence in function and specificity.
CDM69726.1 protein networkhttps://string-db.org/network/1216932.CM240_2602Putative membrane protein.
folA protein networkhttps://string-db.org/network/1216932.CM240_2603Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
thyA protein networkhttps://string-db.org/network/1216932.CM240_2604Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...]
asnB protein networkhttps://string-db.org/network/1216932.CM240_2605Asparagine synthetase [glutamine-hydrolyzing] 1; This family is always found associated with PF00310. Members of this family catalyse the conversion of aspartate to asparagine; High confidence in [...]
CDM69730.1 protein networkhttps://string-db.org/network/1216932.CM240_2606Putative secreted protein.
CDM69731.1 protein networkhttps://string-db.org/network/1216932.CM240_2607Putative secreted protein.
CDM69732.1 protein networkhttps://string-db.org/network/1216932.CM240_2608Hypothetical protein; High confidence in function and specificity.
CDM69733.1 protein networkhttps://string-db.org/network/1216932.CM240_2609Hypothetical protein; Family membership; Belongs to the UPF0237 family.
CDM69734.1 protein networkhttps://string-db.org/network/1216932.CM240_2610ABC transporters belong to the ATP-Binding Cassette superfamily, which uses the hydrolysis of ATP to translocate a variety of compounds across biological membranes. ABC transporters are minimally [...]
CDM69735.1 protein networkhttps://string-db.org/network/1216932.CM240_2611ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many co [...]
CDM69736.1 protein networkhttps://string-db.org/network/1216932.CM240_2612Transcriptional regulator, MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a [...]
CDM69737.1 protein networkhttps://string-db.org/network/1216932.CM240_2613Putative lysophospholipase; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with PF00561. Many members are annotated as [...]
proS protein networkhttps://string-db.org/network/1216932.CM240_2614Proline-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(P [...]
CDM69739.1 protein networkhttps://string-db.org/network/1216932.CM240_2615Aspartate aminotransferase family; This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino aci [...]
pulA3 protein networkhttps://string-db.org/network/1216932.CM240_2616Pullulanase; Hydrolysis of (1->6)-alpha-D-glucosidic linkages in pullulan, amylopectin and glycogen, and in the alpha-and beta-limit dextrins of amylopectin and glycogen; High confidence in funct [...]
amyX protein networkhttps://string-db.org/network/1216932.CM240_2617Putative pullulanase, type I; Pullulan is an unusual, industrially important polysaccharide in which short alpha-1,4 chains (maltotriose) are connected in alpha-1,6 linkages. Enzymes that cleave [...]
CDM69742.1 protein networkhttps://string-db.org/network/1216932.CM240_2618Putative membrane protein.
CDM69743.1 protein networkhttps://string-db.org/network/1216932.CM240_2619Na+/H+ antiporter; This family includes integral membrane proteins,some of which are NA+/H+ antiporters; High confidence in function and specificity.
CDM69744.1 protein networkhttps://string-db.org/network/1216932.CM240_2620Hypothetical protein; The function of this family is unknown, but it is upregulated in response to salt stress in Populus balsamifera. It is also found at the C-terminus of an fructose 1,6-bispho [...]
CDM69745.1 protein networkhttps://string-db.org/network/1216932.CM240_2621Hypothetical protein.
CDM69746.1 protein networkhttps://string-db.org/network/1216932.CM240_2622Hypothetical protein; Family membership.
CDM69747.1 protein networkhttps://string-db.org/network/1216932.CM240_2623HAD-superfamily hydrolase, subfamily IIB; Haloacid dehydrogenase superfamily (HAD superfamily) includes phosphatases, phosphonatases,P-type ATPases,beta-phosphoglucomutases,phosphomannomutases, a [...]
metH protein networkhttps://string-db.org/network/1216932.CM240_2624Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor us [...]
ykbA protein networkhttps://string-db.org/network/1216932.CM240_2625Amino acid permeases are membrane permeases involved in the transport of amino acids into the cell. A number of such proteins have been found to be evolutionary related; High confidence in functi [...]
CDM69750.1 protein networkhttps://string-db.org/network/1216932.CM240_2626Hypothetical protein.
CDM69751.1 protein networkhttps://string-db.org/network/1216932.CM240_2627HesA/MoeB/ThiF family protein; This family contains a repeated domain in ubiquitin activating enzyme E1 and members of the bacterial ThiF/MoeB/HesA family; High confidence in function and specifi [...]
CDM69752.1 protein networkhttps://string-db.org/network/1216932.CM240_2628Chloride channels are a superfamily of poorly understood ion channels consisting of approximately 13 members, Chloride channels display a variety of important physiological and cellular roles tha [...]
CDM69753.1 protein networkhttps://string-db.org/network/1216932.CM240_2629ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological import and export systems. ABC transporters are minimally con [...]
ytlC protein networkhttps://string-db.org/network/1216932.CM240_2630ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters; High confidence in function and specificity.
CDM69755.1 protein networkhttps://string-db.org/network/1216932.CM240_2631ABC transporter periplasmic-binding protein; High confidence in function and specificity.
CDM69756.1 protein networkhttps://string-db.org/network/1216932.CM240_2632Hypothetical protein; High confidence in function and specificity.
CDM69757.1 protein networkhttps://string-db.org/network/1216932.CM240_2633Hypothetical protein; Family membership.
CDM69758.1 protein networkhttps://string-db.org/network/1216932.CM240_2634Beta-lactamase domain-containing protein; Apart from the beta-lactamases and metallo-beta-lactamases, a number of other proteins contain this domain [PUBMED:7588620]. These proteins include thiol [...]
murA protein networkhttps://string-db.org/network/1216932.CM240_2635UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
CDM69760.1 protein networkhttps://string-db.org/network/1216932.CM240_2636Hypothetical protein.
CDM69761.1 protein networkhttps://string-db.org/network/1216932.CM240_2637Hypothetical protein.
CDM69762.1 protein networkhttps://string-db.org/network/1216932.CM240_2638Putative membrane protein.
CDM69763.1 protein networkhttps://string-db.org/network/1216932.CM240_2639Subtilases [1,2] are an extensive family of serine proteases whose catalytic activity is provided by a charge relay system; High confidence in function and specificity.
CDM69764.1 protein networkhttps://string-db.org/network/1216932.CM240_2640Putative membrane protein.
CDM69765.1 protein networkhttps://string-db.org/network/1216932.CM240_2641DNA topoisomerase; ATP-independent breakage of single-stranded DNA,followed by passage and rejoining; High confidence in function and specificity.
birA protein networkhttps://string-db.org/network/1216932.CM240_2642biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
accA protein networkhttps://string-db.org/network/1216932.CM240_2643Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on [...]
accD protein networkhttps://string-db.org/network/1216932.CM240_2644Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its [...]
accC1 protein networkhttps://string-db.org/network/1216932.CM240_2645Acetyl-CoA carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the [...]
fabZ protein networkhttps://string-db.org/network/1216932.CM240_26463-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated an [...]
CDM69771.1 protein networkhttps://string-db.org/network/1216932.CM240_2647Acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the car [...]
fabF protein networkhttps://string-db.org/network/1216932.CM240_26483-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
fabG protein networkhttps://string-db.org/network/1216932.CM240_26493-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongati [...]
fabD protein networkhttps://string-db.org/network/1216932.CM240_2650Malonyl CoA-acyl carrier protein transacylases transfer the malonyl moiety from coenzyme A to acyl-carrier protein. These include proteins involved in fatty acid biosynthesis, antibiotic bosynthe [...]
CDM69775.1 protein networkhttps://string-db.org/network/1216932.CM240_2651Putative enoyl-(Acyl-carrier-protein) reductase II; This oxidoreductase of the 2-nitropropane dioxygenase family is commonly found in apparent operons with genes involved in fatty acid biosynthes [...]
fabH protein networkhttps://string-db.org/network/1216932.CM240_26523-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first c [...]
CDM69777.1 protein networkhttps://string-db.org/network/1216932.CM240_2653Transcriptional regulator, MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a [...]
cinA protein networkhttps://string-db.org/network/1216932.CM240_2654Competence-damage inducible protein; Competence is the ability of a cell to take up exogenous DNA from its environment, resulting in transformation.CinA is the first gene in the competence-induci [...]
CDM69779.1 protein networkhttps://string-db.org/network/1216932.CM240_2655Hypothetical protein; Family membership.
dnaD protein networkhttps://string-db.org/network/1216932.CM240_2656The DnaD protein is a component of the PriA primosome. The PriA primosome functions to recruit the replication fork helicase onto the DNA.Members, both chromosomal or phage-associated, are found [...]
CDM69781.1 protein networkhttps://string-db.org/network/1216932.CM240_2657This group consists of DNA replication protein DnaC and insertion sequence IS21/IS1162 putative ATP-binding proteins. DnaC interacts with DnaB and form a primosome complex for DNA replication; Hi [...]
CDM69782.1 protein networkhttps://string-db.org/network/1216932.CM240_2665Putative pyruvate, phosphate dikinase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzin [...]
CDM69783.1 protein networkhttps://string-db.org/network/1216932.CM240_2666Flavoprotein; High confidence in function and specificity.
CDM69784.1 protein networkhttps://string-db.org/network/1216932.CM240_2667Hypothetical protein; Family membership.
purA protein networkhttps://string-db.org/network/1216932.CM240_2668Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
CDM69786.1 protein networkhttps://string-db.org/network/1216932.CM240_2669Phosphatidylglycerophosphate synthase; All of these members have the ability to catalyse the displacement of CMP from a CDP-alcohol by a second alcohol with formation of a phosphodiester bond and [...]
CDM69787.1 protein networkhttps://string-db.org/network/1216932.CM240_2670Hypothetical protein; High confidence in function and specificity.
CDM69788.1 protein networkhttps://string-db.org/network/1216932.CM240_2671Putative DNA polymerase III epsilon subunit; This entry includes a variety of exonuclease proteins, such as ribonuclease T and the epsilon subunit of DNA polymerase III. Ribonuclease T is respons [...]
nrdA protein networkhttps://string-db.org/network/1216932.CM240_2672Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
nrdB protein networkhttps://string-db.org/network/1216932.CM240_2673Ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; [...]
CDM69791.1 protein networkhttps://string-db.org/network/1216932.CM240_2674Acyl-ACP thioesterase; This entry represents various acyl-acyl carrier protein (ACP) thioesterases (TE) which terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid. T [...]
dnaC protein networkhttps://string-db.org/network/1216932.CM240_2675Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
CDM69793.1 protein networkhttps://string-db.org/network/1216932.CM240_2676Bacterial ATP-dependent proteases. The prototype of those bacterial enzymes is the Escherichia coli La protease (gene lon). La is capable of hydrolyzing large proteins; it degrades short-lived re [...]
rplI protein networkhttps://string-db.org/network/1216932.CM240_267750S ribosomal protein L9; Binds to the 23S rRNA.
CDM69795.1 protein networkhttps://string-db.org/network/1216932.CM240_2678Hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
rpsR protein networkhttps://string-db.org/network/1216932.CM240_267930S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
CDM69797.1 protein networkhttps://string-db.org/network/1216932.CM240_2680ssDNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA [...]
rpsF protein networkhttps://string-db.org/network/1216932.CM240_2681Hypothetical protein; Binds together with S18 to 16S ribosomal RNA.
CDM69799.1 protein networkhttps://string-db.org/network/1216932.CM240_2682Hypothetical protein.
CDM69801.1 protein networkhttps://string-db.org/network/1216932.CM240_2684Hypothetical protein; Family membership.
spo0J protein networkhttps://string-db.org/network/1216932.CM240_2685Stage 0 sporulation protein J; Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition by Soj. It probably interacts with a specific D [...]
soj protein networkhttps://string-db.org/network/1216932.CM240_2686Inhibits the initiation of sporulation, Spo0J antagonizes this inhibition. Soj ultimately inhibits the activation (phosphorylation) of Spo0A; High confidence in function and specificity.
noc protein networkhttps://string-db.org/network/1216932.CM240_2687Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid,especially under conditions that dist [...]
rsmG protein networkhttps://string-db.org/network/1216932.CM240_2688Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
mnmG protein networkhttps://string-db.org/network/1216932.CM240_2689tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
mnmE protein networkhttps://string-db.org/network/1216932.CM240_2690tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
CDM69808.1 protein networkhttps://string-db.org/network/1216932.CM240_2691Putative RNA-binding protein; High confidence in function and specificity.
CDM69809.1 protein networkhttps://string-db.org/network/1216932.CM240_2692Putative membrane protein.
rnpA protein networkhttps://string-db.org/network/1216932.CM240_2693Hypothetical protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein [...]
rpmH protein networkhttps://string-db.org/network/1216932.CM240_2694Hypothetical protein; Belongs to the bacterial ribosomal protein bL34 family.
natA protein networkhttps://string-db.org/network/1216932.CM240_2696ATP-binding transport protein NatA; High confidence in function and specificity.
CDM69814.1 protein networkhttps://string-db.org/network/1216932.CM240_2697Hypothetical protein membrane; Family membership.
CDM69815.1 protein networkhttps://string-db.org/network/1216932.CM240_2698Hypothetical protein; High confidence in function and specificity.
CDM69816.1 protein networkhttps://string-db.org/network/1216932.CM240_2699Hypothetical protein; Family membership.
CDM69817.1 protein networkhttps://string-db.org/network/1216932.CM240_2700Response regulator receiver protein; This domain is found in a variety of bacterial transcriptional regulators. The domain binds to a specific DNA sequence pattern; Hypothetical protein.
CDM69818.1 protein networkhttps://string-db.org/network/1216932.CM240_2701Putative membrane protein; Family membership.
CDM69819.1 protein networkhttps://string-db.org/network/1216932.CM240_2702ABC transporters belong to the ATP-Binding Cassette superfamily, which uses the hydrolysis of ATP to translocate a variety of compounds across biological membranes. ABC transporters are minimally [...]
CDM69820.1 protein networkhttps://string-db.org/network/1216932.CM240_2703Putative membrane protein; Family membership.
CDM69821.1 protein networkhttps://string-db.org/network/1216932.CM240_2704Hypothetical protein; Family membership.
CDM69822.1 protein networkhttps://string-db.org/network/1216932.CM240_2705Putative secreted protein.
CDM69823.1 protein networkhttps://string-db.org/network/1216932.CM240_2706ABC transporter, ATP-binding/permease protein; ABC transporter transmembrane domain is main transmembrane structural unit of ATP-binding cassette transporter which consist of six transmembrane do [...]
CDM69824.1 protein networkhttps://string-db.org/network/1216932.CM240_2707ABC transporter transmembrane domain is main transmembrane structural unit of ATP-binding cassette transporter which consist of six transmembrane domaines. Many members of the ABC transporter fam [...]
CDM69825.1 protein networkhttps://string-db.org/network/1216932.CM240_2708The type example being dipeptidase E (alpha-aspartyl dipeptidase) from Escherichia coli. The family contains alpha-aspartyl dipeptidases (dipeptidase E) and cyanophycinases; High confidence in fu [...]
CDM69826.1 protein networkhttps://string-db.org/network/1216932.CM240_2709S-adenosylmethionine-dependentmethyltransferase; Methyl transfer from the ubiquitous S-adenosyl-L-methionine (SAM) to either nitrogen, oxygen or carbon atoms is frequently employed in diverse org [...]
CDM69827.1 protein networkhttps://string-db.org/network/1216932.CM240_2710The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions from bacterial antibiotic resist [...]
CDM69828.1 protein networkhttps://string-db.org/network/1216932.CM240_2711Hypothetical protein.
CDM69829.1 protein networkhttps://string-db.org/network/1216932.CM240_2712Hypothetical protein; Family membership.
CDM69831.1 protein networkhttps://string-db.org/network/1216932.CM240_2714Heat shock protein Hsp20; Prokaryotic and eukaryotic organisms respond to heat shock or other environmental stress by inducing the synthesis of proteins collectively known as heat-shock proteins [...]
CDM69832.1 protein networkhttps://string-db.org/network/1216932.CM240_2715Heat shock protein Hsp20; Prokaryotic and eukaryotic organisms respond to heat shock or other environmental stress by inducing the synthesis of proteins collectively known as heat-shock proteins [...]
CDM69833.1 protein networkhttps://string-db.org/network/1216932.CM240_2716Hypothetical protein; Family membership.
CDM69834.1 protein networkhttps://string-db.org/network/1216932.CM240_2717Beta-lactamases are enzymes produced by some bacteria that provide resistance to beta-lactam antibiotics like penicillins, cephamycins, and carbapenems (ertapenem),although carbapenems are relati [...]
CDM69835.1 protein networkhttps://string-db.org/network/1216932.CM240_2718Hypothetical protein; High confidence in function and specificity.
CDM69836.1 protein networkhttps://string-db.org/network/1216932.CM240_2719This domain catalyses N-acetyltransferase reactions; High confidence in function and specificity.
CDM69837.1 protein networkhttps://string-db.org/network/1216932.CM240_2720Hypothetical protein; Family membership.
CDM69838.1 protein networkhttps://string-db.org/network/1216932.CM240_2721Hypothetical protein.
CDM69839.1 protein networkhttps://string-db.org/network/1216932.CM240_2722Hypothetical protein; Family membership.
CDM69840.1 protein networkhttps://string-db.org/network/1216932.CM240_2723GnaT-family acetyltransferase; This entry represents a structural domain found in several acyl-CoA acyltransferase enzymes; High confidence in function and specificity.
CDM69841.1 protein networkhttps://string-db.org/network/1216932.CM240_2724Putative Phosphoribosylformylglycinamidine cyclo-ligase; ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole; High confidence in [...]
CDM69842.1 protein networkhttps://string-db.org/network/1216932.CM240_2725Hypothetical protein; High confidence in function and specificity.
CDM69843.1 protein networkhttps://string-db.org/network/1216932.CM240_2726The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions from bacterial antibiotic resist [...]
CDM69844.1 protein networkhttps://string-db.org/network/1216932.CM240_2727Also known as aminoglycoside 6-adenylyltransferase (EC:2.7.7), this protein confers resistance to aminoglycoside antibiotics; High confidence in function and specificity.
CDM69845.1 protein networkhttps://string-db.org/network/1216932.CM240_2728Bifunctional 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/phosphatase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosyl [...]
CDM69846.1 protein networkhttps://string-db.org/network/1216932.CM240_2729C_GCAxxG_C_C family protein; This entry represents a putative redox-active protein of about 140 residues, with four perfectly conserved Cys residues. It includes a CGAXXG motif. Most members are [...]
CDM69847.1 protein networkhttps://string-db.org/network/1216932.CM240_2730Hypothetical protein; High confidence in function and specificity.
CDM69848.1 protein networkhttps://string-db.org/network/1216932.CM240_2731Hypothetical protein.
CDM69849.1 protein networkhttps://string-db.org/network/1216932.CM240_2732Hypothetical protein.
CDM69850.1 protein networkhttps://string-db.org/network/1216932.CM240_2733Hypothetical protein; High confidence in function and specificity.
CDM69851.1 protein networkhttps://string-db.org/network/1216932.CM240_2734Hypothetical protein; High confidence in function and specificity.
CDM69852.1 protein networkhttps://string-db.org/network/1216932.CM240_2735Hypothetical protein; High confidence in function and specificity.
CDM69853.1 protein networkhttps://string-db.org/network/1216932.CM240_2736Acetyltransferase; This entry represents a structural domain found in several acyl-CoA acyltransferase enzymes; High confidence in function and specificity.
CDM69854.1 protein networkhttps://string-db.org/network/1216932.CM240_2737Hypothetical protein; High confidence in function and specificity.
CDM69855.1 protein networkhttps://string-db.org/network/1216932.CM240_2738Putative membrane protein.
CDM69856.1 protein networkhttps://string-db.org/network/1216932.CM240_2739Putative manganese catalase; Catalases are important antioxidant metalloenzymes that catalyse disproportionation of hydrogen peroxide,forming dioxygen and water; High confidence in function and s [...]
CDM69857.1 protein networkhttps://string-db.org/network/1216932.CM240_2740Putative membrane protein.
CDM69858.1 protein networkhttps://string-db.org/network/1216932.CM240_2741L-serine dehydratase is found as a heterodimer of alpha and beta chain or as a fusion of the two chains in a single protein. This enzyme catalyses the deamination of serine to form pyruvate and i [...]
CDM69859.1 protein networkhttps://string-db.org/network/1216932.CM240_2742L-serine dehydratase,iron-sulfur-dependent,alpha subunit; L-serine dehydratase (is a found as a heterodimer of alpha and beta chain or as a fusion of the two chains in a single protein. This enzy [...]
CDM69860.1 protein networkhttps://string-db.org/network/1216932.CM240_2743Putative membrane protein.
CDM69861.1 protein networkhttps://string-db.org/network/1216932.CM240_2744Hypothetical protein; Family membership.
CDM69862.1 protein networkhttps://string-db.org/network/1216932.CM240_2745ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters; High confidence in function and specificity.
CDM69863.1 protein networkhttps://string-db.org/network/1216932.CM240_2746Putative membrane protein.
CDM69864.1 protein networkhttps://string-db.org/network/1216932.CM240_2747RNA polymerase recruits alternative sigma factors as a means of switching on specific regulons. Most bacteria express a multiplicity of sigma factors; High confidence in function and specificity; [...]
flaR protein networkhttps://string-db.org/network/1216932.CM240_2748Putative DNA topology modulator FlaR; High confidence in function and specificity.
CDM69866.1 protein networkhttps://string-db.org/network/1216932.CM240_2749Hypothetical protein; Family membership.
CDM69867.1 protein networkhttps://string-db.org/network/1216932.CM240_2750Hypothetical protein; Family membership.
CDM69868.1 protein networkhttps://string-db.org/network/1216932.CM240_2751AraC family transcriptional regulator; Many bacterial transcription regulation proteins bind DNA through a 'helix-turn-helix' (HTH) motif. One major subfamily of these proteins is related to the [...]
CDM69869.1 protein networkhttps://string-db.org/network/1216932.CM240_2752ABC transporter transmembrane domain is main transmembrane structural unit of ATP-binding cassette transporter which consist of six transmembrane domaines. Many members of the ABC transporter fam [...]
CDM69870.1 protein networkhttps://string-db.org/network/1216932.CM240_2753ABC transporter, permease/ATP-binding protein; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC t [...]
CDM69871.1 protein networkhttps://string-db.org/network/1216932.CM240_2754Radical SAM proteins catalyse diverse reactions,including unusual methylations, isomerisation,sulphur insertion, ring formation, anaerobic oxidation and protein radical formation; High confidence [...]
CDM69872.1 protein networkhttps://string-db.org/network/1216932.CM240_2755Hypothetical protein; Family membership.
CDM69873.1 protein networkhttps://string-db.org/network/1216932.CM240_2756Putative membrane protein.
CDM69874.1 protein networkhttps://string-db.org/network/1216932.CM240_2757Zinc metalloprotease (Elastase); Extracellular zinc metalloprotease.
CDM69875.1 protein networkhttps://string-db.org/network/1216932.CM240_2758Hypothetical protein; Family membership.
CDM69876.1 protein networkhttps://string-db.org/network/1216932.CM240_2759Hypothetical protein; High confidence in function and specificity.
CDM69877.1 protein networkhttps://string-db.org/network/1216932.CM240_2760Hypothetical protein.
CDM69878.1 protein networkhttps://string-db.org/network/1216932.CM240_2761The Nudix family is a protein family of phosphohydrolases.[1][2][3] Using water-mediated catalysis they break a phosphate bond in their substrate to create two products. Nudix stands for Nucleosi [...]
CDM69880.1 protein networkhttps://string-db.org/network/1216932.CM240_2763RNA polymerase, sigma-24 subunit, ECF subfamily; RNA polymerase recruits alternative sigma factors as a means of switching on specific regulons. Most bacteria express a multiplicity of sigma fact [...]
CDM69881.1 protein networkhttps://string-db.org/network/1216932.CM240_2764Hypothetical protein; High confidence in function and specificity.
CDM69882.1 protein networkhttps://string-db.org/network/1216932.CM240_2765ABC transporters belong to the ATP-Binding Cassette superfamily, which uses the hydrolysis of ATP to translocate a variety of compounds across biological membranes. ABC transporters are minimally [...]
CDM69883.1 protein networkhttps://string-db.org/network/1216932.CM240_2766Putative uncharacterized protein; This domain is found in predicted permeases and hypothetical transmembrane proteins; High confidence in function and specificity.
CDM69884.1 protein networkhttps://string-db.org/network/1216932.CM240_2767Putative Endoglucanase A; Hydrolyzes barley beta-glucan,lichenan,carboxymethylcellulose and xylan. It shows preferential activity against the larger cellooligosaccharides (cellohexaose and cellop [...]
xynC protein networkhttps://string-db.org/network/1216932.CM240_2768Glucuronoxylanase XynC; High confidence in function and specificity.
CDM69886.1 protein networkhttps://string-db.org/network/1216932.CM240_2769Hypothetical protein; Frameshift.
CDM69887.1 protein networkhttps://string-db.org/network/1216932.CM240_2770Hypothetical protein; Frameshift; Family membership.
CDM69888.1 protein networkhttps://string-db.org/network/1216932.CM240_2771Hypothetical protein; Family membership.
CDM69889.1 protein networkhttps://string-db.org/network/1216932.CM240_2772Putative membrane protein.
CDM69890.1 protein networkhttps://string-db.org/network/1216932.CM240_2773Putative membrane protein; High confidence in function and specificity.
CDM69891.1 protein networkhttps://string-db.org/network/1216932.CM240_2774Hypothetical protein; High confidence in function and specificity.
CDM69892.1 protein networkhttps://string-db.org/network/1216932.CM240_2775Putative secreted protein.
CDM69893.1 protein networkhttps://string-db.org/network/1216932.CM240_2776Predicted membrane protein involved in D-alanine export; High confidence in function and specificity; Belongs to the membrane-bound acyltransferase family.
CDM69894.1 protein networkhttps://string-db.org/network/1216932.CM240_2777Putative membrane protein; Family membership.
CDM69895.1 protein networkhttps://string-db.org/network/1216932.CM240_2778Hypothetical protein; High confidence in function and specificity.
CDM69896.1 protein networkhttps://string-db.org/network/1216932.CM240_2779Hypothetical protein; High confidence in function and specificity.
CDM69898.1 protein networkhttps://string-db.org/network/1216932.CM240_2781This domain represents transcriptional regulators and is presents in Desulfovibrio vulgaris as Protein Rrf2,Escherichia coli as IscR and Bacillus subtilis as NsrR. Protein Rrf2 is a repressor of [...]
vhb protein networkhttps://string-db.org/network/1216932.CM240_2782Hemoglobin-like protein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O2 and NAD(P)H to convert NO to nitrate,which protect [...]
CDM69900.1 protein networkhttps://string-db.org/network/1216932.CM240_2783Putative membrane protein; Family membership.
CDM69901.1 protein networkhttps://string-db.org/network/1216932.CM240_2784Hypothetical protein; High confidence in function and specificity.
CDM69902.1 protein networkhttps://string-db.org/network/1216932.CM240_2785Putative membrane protein; High confidence in function and specificity.
CDM69903.1 protein networkhttps://string-db.org/network/1216932.CM240_2786Putative membrane protein; High confidence in function and specificity.
sbp protein networkhttps://string-db.org/network/1216932.CM240_2787Sulphate-binding protein (gene sbp or sbpA) and thiosulphate-binding protein (gene cysP) are two structurally related periplasmic bacterial proteins which specifically bind sulphate and thiosulph [...]
cysT protein networkhttps://string-db.org/network/1216932.CM240_2788Sulfate ABC transporter, inner membrane subunit CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
cysW protein networkhttps://string-db.org/network/1216932.CM240_2789Sulfate ABC transporter, system permease protein CysW; Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocatio [...]
cysA protein networkhttps://string-db.org/network/1216932.CM240_2790Sulfate/thiosulfate import ATP-binding protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; B [...]
CDM69908.1 protein networkhttps://string-db.org/network/1216932.CM240_2791Adenylylsulfate reductase subunit alpha; This domain is found in proteins that bind FAD,such as the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alph [...]
CDM69909.1 protein networkhttps://string-db.org/network/1216932.CM240_2792Hypothetical protein.
cysD protein networkhttps://string-db.org/network/1216932.CM240_2793Sulfate adenylyltransferase subunit 2; In Escherichia coli, ATP sulfurylase is a heterodimer composed of two subunits encoded by cysD and cysN, with APS kinase encoded by cysC. These genes are lo [...]
cysN protein networkhttps://string-db.org/network/1216932.CM240_2794Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase [...]
CDM69912.1 protein networkhttps://string-db.org/network/1216932.CM240_2795Anaerobic sulfite reductase subunit C; Sulphite reductases (SiRs) and related nitrite reductases (NiRs) catalyse the six-electron reduction reactions of sulphite to sulphide, and nitrite to ammon [...]
CDM69913.1 protein networkhttps://string-db.org/network/1216932.CM240_2796Putative membrane protein; Family membership.
CDM69914.1 protein networkhttps://string-db.org/network/1216932.CM240_2797Exopolysaccharide biosynthesis protein, putative; This domain, found in various hypothetical bacterial proteins, has no known function; High confidence in function and specificity.
CDM69915.1 protein networkhttps://string-db.org/network/1216932.CM240_2798Putative membrane protein.
CDM69916.1 protein networkhttps://string-db.org/network/1216932.CM240_2799Putative membrane protein.
glyA-2 protein networkhttps://string-db.org/network/1216932.CM240_2800Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
gcvT protein networkhttps://string-db.org/network/1216932.CM240_2801Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
gcvH protein networkhttps://string-db.org/network/1216932.CM240_2802Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
gcvPA protein networkhttps://string-db.org/network/1216932.CM240_2803Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; C [...]
gcvPB protein networkhttps://string-db.org/network/1216932.CM240_2804Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; C [...]
CDM69922.1 protein networkhttps://string-db.org/network/1216932.CM240_2805Hypothetical protein; High confidence in function and specificity.
CDM69923.1 protein networkhttps://string-db.org/network/1216932.CM240_2806Dihydrolipoyl dehydrogenase; The pyridine nucleotide-disulphide oxidoreductases are FAD flavoproteins which contains a pair of redox-active cysteines involved in the transfer of reducing equivale [...]
CDM69924.1 protein networkhttps://string-db.org/network/1216932.CM240_2807Amidohydrolase; This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification. Family M20 are Glutamate carboxypeptidases. Peptidase family [...]
CDM69925.1 protein networkhttps://string-db.org/network/1216932.CM240_2808Hypothetical protein; High confidence in function and specificity.
CDM69926.1 protein networkhttps://string-db.org/network/1216932.CM240_2809MATE efflux family protein; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range of cati [...]
CDM69927.1 protein networkhttps://string-db.org/network/1216932.CM240_2810Hypothetical protein; Family membership.
CDM69928.1 protein networkhttps://string-db.org/network/1216932.CM240_2811Hypothetical protein; Family membership.
CDM69929.1 protein networkhttps://string-db.org/network/1216932.CM240_2812Putative membrane protein.
CDM69930.1 protein networkhttps://string-db.org/network/1216932.CM240_2813Hypothetical protein; Family membership.
yvgN-2 protein networkhttps://string-db.org/network/1216932.CM240_2814The aldo-keto reductase family includes a number of related monomeric NADPH-dependent oxidoreductases, such as aldehyde reductase, aldose reductase, prostaglandin F synthase, xylose reductase, rh [...]
CDM69932.1 protein networkhttps://string-db.org/network/1216932.CM240_2815Uridine kinase family protein; High confidence in function and specificity.
CDM69933.1 protein networkhttps://string-db.org/network/1216932.CM240_2816Putative membrane protein.
CDM69934.1 protein networkhttps://string-db.org/network/1216932.CM240_2817Sigma-70 family RNA polymerase sigma factor; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conserva [...]
CDM69935.2 protein networkhttps://string-db.org/network/1216932.CM240_2818Puatative phosphatidylinositol diacylglycerol-lyase; Phosphatidylinositol-specific phospholipase C, an eukaryotic intracellular enzyme, plays an important role in signal transduction processes. I [...]
CDM69936.1 protein networkhttps://string-db.org/network/1216932.CM240_2819Putative membrane protein.
CDM69937.1 protein networkhttps://string-db.org/network/1216932.CM240_2820Hypothetical protein; High confidence in function and specificity.
CDM69938.1 protein networkhttps://string-db.org/network/1216932.CM240_2821Putative transcriptional regulator; Family membership.
CDM69939.1 protein networkhttps://string-db.org/network/1216932.CM240_2822This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase. It [...]
CDM69940.1 protein networkhttps://string-db.org/network/1216932.CM240_2823Hypothetical protein; High confidence in function and specificity.
CDM69941.1 protein networkhttps://string-db.org/network/1216932.CM240_2824Hypothetical protein; High confidence in function and specificity.
CDM69942.1 protein networkhttps://string-db.org/network/1216932.CM240_2825Hypothetical protein; Family membership.
CDM69943.1 protein networkhttps://string-db.org/network/1216932.CM240_2826Hypothetical protein; High confidence in function and specificity.
CDM69944.1 protein networkhttps://string-db.org/network/1216932.CM240_2827Hypothetical protein; Family membership.
CDM69945.1 protein networkhttps://string-db.org/network/1216932.CM240_2828The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions from bacterial antibiotic resist [...]
CDM69946.1 protein networkhttps://string-db.org/network/1216932.CM240_2829Alpha/beta hydrolase; High confidence in function and specificity.
CDM69947.1 protein networkhttps://string-db.org/network/1216932.CM240_2830DeoR-family transcriptional regulator; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site [1]. DeorC senses diverse sugar [...]
soj-2 protein networkhttps://string-db.org/network/1216932.CM240_2831SpoOJ regulator protein; ATPases involved in chromosome partitioning; High confidence in function and specificity.
CDM69949.1 protein networkhttps://string-db.org/network/1216932.CM240_2832Proteins containing this domain, appear to be related to the Escherichia coli plasmid protein ParB,which preferentially cleaves single-stranded DNA. ParB also nicks supercoiled plasmid DNA prefer [...]
CDM69950.1 protein networkhttps://string-db.org/network/1216932.CM240_2833Putative membrane protein.
CDM69951.1 protein networkhttps://string-db.org/network/1216932.CM240_2834Hypothetical protein.
CDM69952.1 protein networkhttps://string-db.org/network/1216932.CM240_2835Hypothetical protein; Family membership.
CDM69953.1 protein networkhttps://string-db.org/network/1216932.CM240_2836Hypothetical protein; Family membership.
CDM69954.1 protein networkhttps://string-db.org/network/1216932.CM240_2837Trans-aconitate 2-methyltransferase; Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate; High confidence in function and specificity.
CDM69955.1 protein networkhttps://string-db.org/network/1216932.CM240_2838Hypothetical protein; Family membership.
CDM69956.1 protein networkhttps://string-db.org/network/1216932.CM240_2839Hypothetical protein; High confidence in function and specificity.
dapB-2 protein networkhttps://string-db.org/network/1216932.CM240_2840Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
CDM69958.1 protein networkhttps://string-db.org/network/1216932.CM240_2841Transcriptional regulator, LysR family; The lysR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 60 residues present in lysR-type transcriptional regulators (LTTR [...]
asd-2 protein networkhttps://string-db.org/network/1216932.CM240_2842Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate; High confidence in function and specificity; Belongs to t [...]
CDM69960.1 protein networkhttps://string-db.org/network/1216932.CM240_2843Putative secreted protein.
CDM69961.1 protein networkhttps://string-db.org/network/1216932.CM240_2844Hypothetical protein; High confidence in function and specificity.
CDM69962.1 protein networkhttps://string-db.org/network/1216932.CM240_2845Putative membrane protein.
CDM69963.1 protein networkhttps://string-db.org/network/1216932.CM240_2846These peptidases have gamma-glutamyl hydrolase activity; that is they catalyse the cleavage of the gamma-glutamyl bond in poly-gamma-glutamyl substrates. They are structurally related to PF00117 [...]
CDM69965.1 protein networkhttps://string-db.org/network/1216932.CM240_2848Putative transport protein; High confidence in function and specificity.
CDM69966.1 protein networkhttps://string-db.org/network/1216932.CM240_2849Transcriptional regulator; The tetR-type HTH domain is a DNA-binding,helix-turn-helix (HTH) domain of about 60 residues present in the tetR family of prokaryotic transcription regulators. Several [...]
ohyA protein networkhttps://string-db.org/network/1216932.CM240_2850Oleate hydratase catalyses the hydration of oleate at its cis-9-double bond to yield 10-hydroxyoctadecanoate. The hydration of unsaturated fatty acids is suggested to be a detoxification mechanis [...]
CDM69968.1 protein networkhttps://string-db.org/network/1216932.CM240_2851Hypothetical protein; High confidence in function and specificity.
CDM69969.1 protein networkhttps://string-db.org/network/1216932.CM240_2852MerR-family transcriptional regulator; The merR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 70 residues present in the merR family of transcriptional regulato [...]
CDM69970.1 protein networkhttps://string-db.org/network/1216932.CM240_2853Putative multidrug efflux protein; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range [...]
glnS-2 protein networkhttps://string-db.org/network/1216932.CM240_2854Glutamine-tRNA ligase; The aminoacyl-tRNA synthetases (EC 6.1.1.) catalyse the attachment of an amino acid to its cognate transfer RNA molecule in a highly specific two-step reaction. These prote [...]
CDM69972.1 protein networkhttps://string-db.org/network/1216932.CM240_2855Putative secreted protein.
CDM69973.1 protein networkhttps://string-db.org/network/1216932.CM240_2856Putative secreted protein.
CDM69974.1 protein networkhttps://string-db.org/network/1216932.CM240_2857Two component transcriptional regulator, winged helix family; This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA b [...]
CDM69975.1 protein networkhttps://string-db.org/network/1216932.CM240_2858Integral membrane sensor signal transduction histidine kinase; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved compo [...]
bceA-2 protein networkhttps://string-db.org/network/1216932.CM240_2859Bacitracin export ATP-binding protein; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are th [...]
CDM69977.1 protein networkhttps://string-db.org/network/1216932.CM240_2860This family represents the permease component of ABC-type antimicrobial peptide transport systems; High confidence in function and specificity.
CDM69978.1 protein networkhttps://string-db.org/network/1216932.CM240_2861Putative membrane protein.
rpsD2 protein networkhttps://string-db.org/network/1216932.CM240_286230S ribosomal protein S4 B; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
CDM69980.1 protein networkhttps://string-db.org/network/1216932.CM240_2863Transcriptional regulator, LysR family; The lysR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 60 residues present in lysR-type transcriptional regulators (LTTR [...]
metE protein networkhttps://string-db.org/network/1216932.CM240_28645-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; B [...]
CDM69982.1 protein networkhttps://string-db.org/network/1216932.CM240_2865Putative membrane protein.
CDM69983.1 protein networkhttps://string-db.org/network/1216932.CM240_2866Hypothetical protein; High confidence in function and specificity.
CDM69984.1 protein networkhttps://string-db.org/network/1216932.CM240_2867Hypothetical protein; Family membership.
CDM69985.1 protein networkhttps://string-db.org/network/1216932.CM240_2868Hypothetical protein; Family membership.
CDM69986.1 protein networkhttps://string-db.org/network/1216932.CM240_2869Putative membrane protein.
CDM69987.1 protein networkhttps://string-db.org/network/1216932.CM240_2870Hypothetical protein; Family membership.
CDM69988.1 protein networkhttps://string-db.org/network/1216932.CM240_2871Putative membrane protein.
CDM69989.1 protein networkhttps://string-db.org/network/1216932.CM240_2872Hypothetical protein; Family membership.
CDM69990.1 protein networkhttps://string-db.org/network/1216932.CM240_2873Proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues. The best studied of these proteins is the prokaryotic catabolite gene activator (also known a [...]
CDM69991.1 protein networkhttps://string-db.org/network/1216932.CM240_2874Hypothetical protein; Family membership.
CDM69992.1 protein networkhttps://string-db.org/network/1216932.CM240_2875Hypothetical protein; Family membership.
CDM69993.1 protein networkhttps://string-db.org/network/1216932.CM240_2876Hypothetical protein.
CDM69994.1 protein networkhttps://string-db.org/network/1216932.CM240_2877Hypothetical protein; Family membership.
CDM69995.1 protein networkhttps://string-db.org/network/1216932.CM240_2878The alpha/beta hydrolase fold is common to a number of hydrolytic enzymes of widely differing phylogenetic origin and catalytic function; High confidence in function and specificity.
CDM69996.1 protein networkhttps://string-db.org/network/1216932.CM240_2879Hypothetical protein; High confidence in function and specificity.
CDM69997.1 protein networkhttps://string-db.org/network/1216932.CM240_2880Protein DJ-1; This entry represents a subset of the functionally diverse DJ-1 domain superfamily. The only functionally and structurally characterised protein in this entry is the Pseudomonas flu [...]
CDM69998.1 protein networkhttps://string-db.org/network/1216932.CM240_2881Acetyltransferase; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins; High confidence in function and specificity.
CDM69999.1 protein networkhttps://string-db.org/network/1216932.CM240_2882Hypothetical protein; High confidence in function and specificity.
CDM70000.1 protein networkhttps://string-db.org/network/1216932.CM240_2883ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters,ABC transporters belong to the ATP-Binding Cassette superfamily, which uses the hydrolysis of AT [...]
CDM70001.1 protein networkhttps://string-db.org/network/1216932.CM240_2884Hypothetical protein; High confidence in function and specificity.
CDM70002.1 protein networkhttps://string-db.org/network/1216932.CM240_2885Hypothetical protein; High confidence in function and specificity.
CDM70003.1 protein networkhttps://string-db.org/network/1216932.CM240_2886Putative membrane protein; Family membership.
hcp1 protein networkhttps://string-db.org/network/1216932.CM240_2887Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
CDM70005.1 protein networkhttps://string-db.org/network/1216932.CM240_2888AraC family transcriptional regulator; The many bacterial transcription regulation proteins which bind DNA through a 'helix-turn-helix' motif can be classified into subfamilies on the basis of se [...]
CDM70006.1 protein networkhttps://string-db.org/network/1216932.CM240_2889Oligo-1,6-glucosidase; Glycoside hydrolase family 13 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond betwe [...]
maa protein networkhttps://string-db.org/network/1216932.CM240_2890Maltose O-acetyltransferase; High confidence in function and specificity.
ADE16 protein networkhttps://string-db.org/network/1216932.CM240_2891Bifunctional purine biosynthesis protein ADE16; This is a family of bifunctional enzymes catalysing the last two steps in de novo purine biosynthesis. The bifunctional enzyme is found in both pro [...]
CDM70009.1 protein networkhttps://string-db.org/network/1216932.CM240_2892Hypothetical protein.
CDM70010.1 protein networkhttps://string-db.org/network/1216932.CM240_2893Hypothetical protein; High confidence in function and specificity.
CDM70011.1 protein networkhttps://string-db.org/network/1216932.CM240_2894Hypothetical protein.
CDM70012.1 protein networkhttps://string-db.org/network/1216932.CM240_2895Hypothetical protein.
CDM70013.1 protein networkhttps://string-db.org/network/1216932.CM240_2896This group of serine peptidases belong to MEROPS peptidase family S26 (signal peptidase I family, clan SF),subfamily S26A.At least 3 eubacterial leader peptidases are known: murein prelipoprotein [...]
CDM70016.1 protein networkhttps://string-db.org/network/1216932.CM240_2899Hypothetical protein; Family membership.
CDM70017.1 protein networkhttps://string-db.org/network/1216932.CM240_2900Putative membrane protein.
CDM70018.1 protein networkhttps://string-db.org/network/1216932.CM240_2901Hypothetical protein.
CDM70019.1 protein networkhttps://string-db.org/network/1216932.CM240_2902Hypothetical protein; High confidence in function and specificity.
CDM70020.1 protein networkhttps://string-db.org/network/1216932.CM240_2903Hypothetical protein; Family membership; Belongs to the peptidase S51 family.
CDM70021.1 protein networkhttps://string-db.org/network/1216932.CM240_2904Hypothetical protein; Family membership.
CDM70022.1 protein networkhttps://string-db.org/network/1216932.CM240_2905The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions from bacterial antibiotic resist [...]
CDM70023.1 protein networkhttps://string-db.org/network/1216932.CM240_2906Hypothetical protein.
CDM70024.1 protein networkhttps://string-db.org/network/1216932.CM240_2907Hypothetical protein.
CDM70025.1 protein networkhttps://string-db.org/network/1216932.CM240_2908Hypothetical protein; High confidence in function and specificity.
CDM70026.1 protein networkhttps://string-db.org/network/1216932.CM240_2909Hypothetical protein; High confidence in function and specificity.
CDM70027.1 protein networkhttps://string-db.org/network/1216932.CM240_2910GCN5-related N-acetyltransferase; High confidence in function and specificity.
CDM70028.1 protein networkhttps://string-db.org/network/1216932.CM240_2911Hypothetical protein; Family membership.
CDM70029.1 protein networkhttps://string-db.org/network/1216932.CM240_2912Filamentation induced by cAMP protein Fic; The Fic/DOC protein family is a family of proteins which includes the Fic (filamentation induced by cAMP) protein and doc (death on curing) protein. The [...]
CDM70030.1 protein networkhttps://string-db.org/network/1216932.CM240_2913TfoX domain protein; TfoX may play a key role in the development of genetic competence by regulating the expression of late competence-specific genes; Family membership.
CDM70031.1 protein networkhttps://string-db.org/network/1216932.CM240_2914The Nudix family is a protein family of phosphohydrolases. Using water-mediated catalysis they break a phosphate bond in their substrate to create two products. Nudix stands for Nucleoside Diphos [...]
CDM70032.1 protein networkhttps://string-db.org/network/1216932.CM240_2915Acetyltransferase, GNAT family; Acetyltransferase (or transacetylase) is a type of transferase enzyme that transfers an acetyl group; High confidence in function and specificity.
CDM70033.1 protein networkhttps://string-db.org/network/1216932.CM240_2916Hypothetical protein.
CDM70034.1 protein networkhttps://string-db.org/network/1216932.CM240_2917Putative membrane protein; High confidence in function and specificity.
YdeE1 protein networkhttps://string-db.org/network/1216932.CM240_2918AraC-family transcriptional regulator; The many bacterial transcription regulation proteins which bind DNA through a 'helix-turn-helix' motif can be classified into subfamilies on the basis of se [...]
CDM70036.1 protein networkhttps://string-db.org/network/1216932.CM240_2919Hypothetical protein; High confidence in function and specificity.
CDM70037.1 protein networkhttps://string-db.org/network/1216932.CM240_2920Hypothetical protein; High confidence in function and specificity.
CDM70038.1 protein networkhttps://string-db.org/network/1216932.CM240_2921Hypothetical protein; Family membership.
CDM70039.1 protein networkhttps://string-db.org/network/1216932.CM240_2922Hypothetical protein; High confidence in function and specificity.
CDM70040.1 protein networkhttps://string-db.org/network/1216932.CM240_2923Putative membrane protein.
CDM70041.1 protein networkhttps://string-db.org/network/1216932.CM240_2924Hypothetical protein.
selO protein networkhttps://string-db.org/network/1216932.CM240_2925Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.
CDM70043.1 protein networkhttps://string-db.org/network/1216932.CM240_2926Hypothetical protein; Family membership.
CDM70044.1 protein networkhttps://string-db.org/network/1216932.CM240_2927Hypothetical protein; Family membership.
CDM70045.1 protein networkhttps://string-db.org/network/1216932.CM240_2928Hypothetical protein; Family membership.
CDM70046.1 protein networkhttps://string-db.org/network/1216932.CM240_2929Hypothetical protein; High confidence in function and specificity.
CDM70047.1 protein networkhttps://string-db.org/network/1216932.CM240_2930Hypothetical protein; High confidence in function and specificity.
CDM70048.1 protein networkhttps://string-db.org/network/1216932.CM240_2931DNA polymerase III subunit epsilon; This family includes a variety of exonuclease proteins, such as ribonuclease T and the epsilon subunit of DNA polymerase III; High confidence in function and s [...]
CDM70049.1 protein networkhttps://string-db.org/network/1216932.CM240_2932Hypothetical protein.
sinIM protein networkhttps://string-db.org/network/1216932.CM240_2933Modification methylase SinI; High confidence in function and specificity.
CDM70051.1 protein networkhttps://string-db.org/network/1216932.CM240_2934This family includes many TdeIII restriction endonucleases that recognise and cleave at GGNCC sites. TdeIII cleave unmethylated double-stranded DNA; High confidence in function and specificity.
CDM70052.1 protein networkhttps://string-db.org/network/1216932.CM240_2935Hypothetical protein.
CDM70053.1 protein networkhttps://string-db.org/network/1216932.CM240_2936Hypothetical protein; Family membership.
CDM70054.1 protein networkhttps://string-db.org/network/1216932.CM240_2937Hypothetical protein.
CDM70055.1 protein networkhttps://string-db.org/network/1216932.CM240_2938Hypothetical protein.
CDM70056.1 protein networkhttps://string-db.org/network/1216932.CM240_2939DEAD/DEAH box helicase domain-containing protein; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related pro [...]
CDM70057.1 protein networkhttps://string-db.org/network/1216932.CM240_2940ABC transporter, ATP-binding protein; Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding dom [...]
CDM70058.1 protein networkhttps://string-db.org/network/1216932.CM240_2941Two component transcriptional regulator, winged helix family; CheY is a member of the response regulator family in bacterial two-component signalling systems, where CheY receives the signal from [...]
CDM70059.1 protein networkhttps://string-db.org/network/1216932.CM240_2942Signal transducing histidine kinases are the key elements in two-component signal transduction systems,which control complex processes such as the initiation of development in microorganisms; Hig [...]
CDM70060.1 protein networkhttps://string-db.org/network/1216932.CM240_2943Putative membrane protein; Family membership.
CDM70061.1 protein networkhttps://string-db.org/network/1216932.CM240_2944Hypothetical protein; Family membership.
CDM70062.1 protein networkhttps://string-db.org/network/1216932.CM240_2945Acetyltransferase; This domain catalyses N-acetyltransferase reactions; High confidence in function and specificity.
CDM70063.1 protein networkhttps://string-db.org/network/1216932.CM240_2946Integral membrane sensor signal transduction histidine kinase; A two-component regulatory system serves as a basic stimulus-response coupling mechanism to allow organisms to sense and respond to [...]
CDM70064.1 protein networkhttps://string-db.org/network/1216932.CM240_2947Two component transcriptional regulator, LuxR family; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a [...]
yfiL protein networkhttps://string-db.org/network/1216932.CM240_2948ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters; High confidence in function and specificity.
CDM70066.1 protein networkhttps://string-db.org/network/1216932.CM240_2949ABC-2 type transporter; High confidence in function and specificity.
CDM70067.1 protein networkhttps://string-db.org/network/1216932.CM240_2950ABC-2 type transporter; High confidence in function and specificity.
CDM70068.1 protein networkhttps://string-db.org/network/1216932.CM240_2951Hypothetical protein; High confidence in function and specificity.
CDM70070.1 protein networkhttps://string-db.org/network/1216932.CM240_2953Acetyltransferase; High confidence in function and specificity.
CDM70071.1 protein networkhttps://string-db.org/network/1216932.CM240_2954Hypothetical protein; Frameshift; High confidence in function and specificity.
CDM70072.1 protein networkhttps://string-db.org/network/1216932.CM240_2955Putative secreted protein.
CDM70073.1 protein networkhttps://string-db.org/network/1216932.CM240_2956Members of this family are transcriptional regulators that appear to be related to the PF01047 family. This family includes PadR Q9EXE6 a protein that is involved in negative regulation of phenol [...]
CDM70075.1 protein networkhttps://string-db.org/network/1216932.CM240_2958Hypothetical protein; High confidence in function and specificity.
CDM70076.1 protein networkhttps://string-db.org/network/1216932.CM240_2959This domain is found to the N-terminus of the PF01432 domain in bacterial and archaeal proteins including Oligoendopeptidase F. An example of this protein is Lactococcus lactis PepF; High confide [...]
CDM70077.1 protein networkhttps://string-db.org/network/1216932.CM240_2960Sulfate transporter family protein; A number of proteins involved in the transport of sulphate across a membrane as well as some yet uncharacterised proteins have been shown to be evolutionary re [...]
CDM70078.1 protein networkhttps://string-db.org/network/1216932.CM240_2961Methylase involved in ubiquinone/menaquinone biosynthesis; Methyl transfer from the ubiquitous S-adenosyl-L-methionine (SAM) to either nitrogen, oxygen or carbon atoms is frequently employed in d [...]
CDM70079.1 protein networkhttps://string-db.org/network/1216932.CM240_2962Hypothetical protein.
CDM70080.1 protein networkhttps://string-db.org/network/1216932.CM240_2963Protein of unknown function DUF161; High confidence in function and specificity.
cshA-2 protein networkhttps://string-db.org/network/1216932.CM240_2964DEAD-box ATP-dependent RNA helicase CshA; May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. Unwinds dsRNA in both [...]
CDM70082.1 protein networkhttps://string-db.org/network/1216932.CM240_2965Putative membrane protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
rnjA-2 protein networkhttps://string-db.org/network/1216932.CM240_2966Ribonuclease J 1; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
CDM70084.1 protein networkhttps://string-db.org/network/1216932.CM240_2967Hypothetical protein.
CDM70085.1 protein networkhttps://string-db.org/network/1216932.CM240_2968Putative membrane protein.
CDM70086.1 protein networkhttps://string-db.org/network/1216932.CM240_2969Transporter, dicarboxylate/amino acid:cation (Na+ or H+) symporter (DAACS) family protein; It has been shown that integral membrane proteins that mediate the uptake of a wide variety of molecules [...]
CDM70087.1 protein networkhttps://string-db.org/network/1216932.CM240_2970Putative membrane protein; High confidence in function and specificity.
CDM70088.1 protein networkhttps://string-db.org/network/1216932.CM240_2971Hypothetical protein; High confidence in function and specificity.
CDM70089.1 protein networkhttps://string-db.org/network/1216932.CM240_2972ABC transporter permease; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of th [...]
CDM70090.1 protein networkhttps://string-db.org/network/1216932.CM240_2973ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component e; ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters; High confidence in [...]
CDM70091.1 protein networkhttps://string-db.org/network/1216932.CM240_2974ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily, which uses the hydrolysis of ATP to energise diverse biological systems. ABC transporters minimally consist of two conserved [...]
CDM70092.1 protein networkhttps://string-db.org/network/1216932.CM240_2975Hypothetical protein; High confidence in function and specificity.
CDM70093.1 protein networkhttps://string-db.org/network/1216932.CM240_2976A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related. The catalytic dom [...]
CDM70094.1 protein networkhttps://string-db.org/network/1216932.CM240_2977Hypothetical protein; High confidence in function and specificity.
pyrE protein networkhttps://string-db.org/network/1216932.CM240_2978Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
CDM70096.1 protein networkhttps://string-db.org/network/1216932.CM240_2979Hypothetical protein.
CDM70097.1 protein networkhttps://string-db.org/network/1216932.CM240_2980This family includes bacterial periplasmic binding proteins. Several of which are involved in iron transport; Conserved hypothetical protein.
CDM70098.1 protein networkhttps://string-db.org/network/1216932.CM240_2981Transport system permease protein; This is a subfamily of bacterial binding-protein-dependent transport systems family, and includes transport system permease proteins involved in the transport a [...]
CDM70099.1 protein networkhttps://string-db.org/network/1216932.CM240_2982Transport system permease; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport sys [...]
fhuC protein networkhttps://string-db.org/network/1216932.CM240_2983ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM70101.1 protein networkhttps://string-db.org/network/1216932.CM240_2984Major facilitator superfamily transporter; Among the different families of transporter, only two occur ubiquitously in all classifications of organisms. These are the ATP-Binding Cassette (ABC) s [...]
CDM70102.1 protein networkhttps://string-db.org/network/1216932.CM240_2985Putative membrane protein.
mutT protein networkhttps://string-db.org/network/1216932.CM240_2986The Nudix family is a protein family of phosphohydrolases. Using water-mediated catalysis they break a phosphate bond in their substrate to create two products. Nudix stands for Nucleoside Diphos [...]
CDM70104.1 protein networkhttps://string-db.org/network/1216932.CM240_2987Putative membrane protein; High confidence in function and specificity.
CDM70105.1 protein networkhttps://string-db.org/network/1216932.CM240_2988Methyl-accepting chemotaxis sensory transducer; Bacterial chemotactic-signal transducers are proteins that respond to changes in the concentration of attractants and repellents in the environment [...]
CDM70106.1 protein networkhttps://string-db.org/network/1216932.CM240_2989Hypothetical protein.
CDM70107.1 protein networkhttps://string-db.org/network/1216932.CM240_2990Hypothetical protein; Family membership.
CDM70108.1 protein networkhttps://string-db.org/network/1216932.CM240_2991Oligoendopeptidase, M3 family; This is the Thimet oligopeptidase family, large family of mammalian and bacterial oligopeptidases that cleave medium sized peptides. The group also contains mitocho [...]
hcp3 protein networkhttps://string-db.org/network/1216932.CM240_2992Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
CDM70110.1 protein networkhttps://string-db.org/network/1216932.CM240_2993Hypothetical protein; High confidence in function and specificity.
CDM70111.1 protein networkhttps://string-db.org/network/1216932.CM240_2994Hypothetical protein.
CDM70112.1 protein networkhttps://string-db.org/network/1216932.CM240_2995tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; [...]
polC-2 protein networkhttps://string-db.org/network/1216932.CM240_2996DNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
yjeM protein networkhttps://string-db.org/network/1216932.CM240_2997Inner membrane transporter YjeM; Amino acid permeases are membrane permeases involved in the transport of amino acids into the cell. A number of such proteins have been found to be evolutionary r [...]
CDM70115.1 protein networkhttps://string-db.org/network/1216932.CM240_2998FliB family protein; High confidence in function and specificity.
eno-2 protein networkhttps://string-db.org/network/1216932.CM240_2999Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
CDM70117.1 protein networkhttps://string-db.org/network/1216932.CM240_3000Hypothetical protein; High confidence in function and specificity.
ilvD protein networkhttps://string-db.org/network/1216932.CM240_3001Dihydroxy-acid dehydratase (gene ilvD or ILV3) which catalyzes the fourth step in the biosynthesis of isoleucine and valine, the dehydratation of 2,3-dihydroxy-isovaleic acid into alpha-ketoisova [...]
CDM70119.1 protein networkhttps://string-db.org/network/1216932.CM240_3002Hypothetical protein.
CDM70120.1 protein networkhttps://string-db.org/network/1216932.CM240_3003Hypothetical protein; Family membership.
CDM70121.1 protein networkhttps://string-db.org/network/1216932.CM240_3004Hypothetical protein; Family membership.
CDM70122.1 protein networkhttps://string-db.org/network/1216932.CM240_3005Hypothetical protein; High confidence in function and specificity.
CDM70123.1 protein networkhttps://string-db.org/network/1216932.CM240_3006Hypothetical protein.
nrgA protein networkhttps://string-db.org/network/1216932.CM240_3007Ammonium transporter NrgA; High confidence in function and specificity.
CDM70125.1 protein networkhttps://string-db.org/network/1216932.CM240_3008P-II is a protein of about 110 amino acid residues extremely well conserved. The tyrosine which is uridylated is located in the central part of the protein. In cyanobacteria, P-II seems to be pho [...]
CDM70126.1 protein networkhttps://string-db.org/network/1216932.CM240_3009Hypothetical protein.
CDM70127.1 protein networkhttps://string-db.org/network/1216932.CM240_3010Hypothetical protein.
CDM70128.1 protein networkhttps://string-db.org/network/1216932.CM240_3011Hypothetical protein; High confidence in function and specificity.
pcp protein networkhttps://string-db.org/network/1216932.CM240_3012Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
CDM70130.1 protein networkhttps://string-db.org/network/1216932.CM240_3013Permease; This family consists of several putative bacterial membrane proteins. The function of this family is unclear; High confidence in function and specificity.
CDM70131.1 protein networkhttps://string-db.org/network/1216932.CM240_3014Permease; High confidence in function and specificity.
CDM70132.1 protein networkhttps://string-db.org/network/1216932.CM240_3015FAD dependent oxidoreductase; High confidence in function and specificity.
CDM70133.1 protein networkhttps://string-db.org/network/1216932.CM240_3016Hypothetical protein; Frameshift; Family membership.
CDM70134.1 protein networkhttps://string-db.org/network/1216932.CM240_3017Hypothetical protein; Family membership.
CDM70135.1 protein networkhttps://string-db.org/network/1216932.CM240_3018ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM70136.1 protein networkhttps://string-db.org/network/1216932.CM240_3019Hypothetical protein; High confidence in function and specificity.
CDM70137.1 protein networkhttps://string-db.org/network/1216932.CM240_3020MATE efflux family protein; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range of cati [...]
CDM70138.1 protein networkhttps://string-db.org/network/1216932.CM240_3021Spermidine/putrescine ABC transporter, permease protein; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological impo [...]
CDM70139.1 protein networkhttps://string-db.org/network/1216932.CM240_3022ABC transporters are minimally constituted of two conserved regions: a highly conserved ATP binding cassette (ABC) and a less conserved transmembrane domain (TMD). These regions can be found on t [...]
CDM70140.1 protein networkhttps://string-db.org/network/1216932.CM240_3023ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological import and export systems. ABC transporters are minimally con [...]
CDM70141.1 protein networkhttps://string-db.org/network/1216932.CM240_3024ABC transporter substrate-binding protein; The bacterial periplasmic spermidine/putrescine-binding proteins are involved in the polyamine transport system. They are required for the activity of t [...]
CDM70142.1 protein networkhttps://string-db.org/network/1216932.CM240_3025Amidohydrolase domain protein; This family of enzymes are a a large metal dependent hydrolase superfamily. The family includes Adenine deaminasethat hydrolyses adenine to form hypoxanthine and am [...]
CDM70144.1 protein networkhttps://string-db.org/network/1216932.CM240_3027Hypothetical protein; Family membership.
CDM70145.1 protein networkhttps://string-db.org/network/1216932.CM240_3028Hypothetical protein; Family membership.
CDM70146.1 protein networkhttps://string-db.org/network/1216932.CM240_3029Hypothetical protein; Family membership.
CDM70147.1 protein networkhttps://string-db.org/network/1216932.CM240_3030Hypothetical protein; High confidence in function and specificity.
CDM70148.1 protein networkhttps://string-db.org/network/1216932.CM240_3031Signal peptidases (SPases)(also known as leader peptidases) remove the signal peptides from secretory proteins. In prokaryotes three types of SPases are known: type I (gene lepB) which is respons [...]
CDM70149.1 protein networkhttps://string-db.org/network/1216932.CM240_3032Hypothetical protein; Family membership.
CDM70150.1 protein networkhttps://string-db.org/network/1216932.CM240_3033Hypothetical protein; Family membership; Belongs to the peptidase S26 family.
CDM70151.1 protein networkhttps://string-db.org/network/1216932.CM240_3034Putative secreted protein.
CDM70152.1 protein networkhttps://string-db.org/network/1216932.CM240_3035Hypothetical protein; Family membership.
CDM70153.1 protein networkhttps://string-db.org/network/1216932.CM240_3036Putative membrane protein.
CDM70154.1 protein networkhttps://string-db.org/network/1216932.CM240_3037Hypothetical protein.
CDM70155.1 protein networkhttps://string-db.org/network/1216932.CM240_3038Putative membrane protein.
CDM70156.1 protein networkhttps://string-db.org/network/1216932.CM240_3039Hypothetical protein; Family membership.
CDM70157.1 protein networkhttps://string-db.org/network/1216932.CM240_3040Hypothetical protein.
CDM70158.1 protein networkhttps://string-db.org/network/1216932.CM240_3041Carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein; Family membership.
CDM70159.1 protein networkhttps://string-db.org/network/1216932.CM240_3042Hypothetical protein; Family membership.
CDM70160.1 protein networkhttps://string-db.org/network/1216932.CM240_3043Putative membrane protein.
CDM70161.1 protein networkhttps://string-db.org/network/1216932.CM240_3044Putative membrane protein.
CDM70162.1 protein networkhttps://string-db.org/network/1216932.CM240_3045Putative membrane protein.
CDM70163.1 protein networkhttps://string-db.org/network/1216932.CM240_3046Putative membrane protein.
CDM70164.1 protein networkhttps://string-db.org/network/1216932.CM240_3047Putative membrane protein; High confidence in function and specificity.
CDM70165.1 protein networkhttps://string-db.org/network/1216932.CM240_3048LysR family transcriptional regulator; The structure of this domain is known and is; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
CDM70166.1 protein networkhttps://string-db.org/network/1216932.CM240_3049Hypothetical protein; Family membership.
CDM70167.1 protein networkhttps://string-db.org/network/1216932.CM240_3050Putative thiazole biosynthesis protein; Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes [Coenzyme metabolism / General function prediction only]; High confidence in function [...]
CDM70168.1 protein networkhttps://string-db.org/network/1216932.CM240_3051Putative secreted protein.
CDM70169.1 protein networkhttps://string-db.org/network/1216932.CM240_3052ABC transporter, ATP-binding/permease protein; ABC transporter transmembrane domain is main transmembrane structural unit of ATP-binding cassette transporter which consist of six transmembrane do [...]
CDM70170.1 protein networkhttps://string-db.org/network/1216932.CM240_3053ABC transporter, permease/ATP-binding protein; ABC transporter transmembrane domain is main transmembrane structural unit of ATP-binding cassette transporter which consist of six transmembrane do [...]
CDM70171.1 protein networkhttps://string-db.org/network/1216932.CM240_3054Hypothetical protein.
CDM70172.1 protein networkhttps://string-db.org/network/1216932.CM240_3055Hypothetical protein; Family membership.
gshAB protein networkhttps://string-db.org/network/1216932.CM240_3056Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate-- [...]
CDM70174.1 protein networkhttps://string-db.org/network/1216932.CM240_3057Hypothetical protein; High confidence in function and specificity.
CDM70175.1 protein networkhttps://string-db.org/network/1216932.CM240_3058Hypothetical protein.
CDM70176.1 protein networkhttps://string-db.org/network/1216932.CM240_3059Hypothetical protein.
CDM70177.1 protein networkhttps://string-db.org/network/1216932.CM240_3060Hypothetical protein.
CDM70178.1 protein networkhttps://string-db.org/network/1216932.CM240_3061CheC domain protein; This entry represents a domain found in chemotaxis phosphatase CheX, which is responsible for modulating the bacterial swimming behavioiur in the presence of external chemica [...]
CDM70179.1 protein networkhttps://string-db.org/network/1216932.CM240_3062Hypothetical protein.
rbr3B protein networkhttps://string-db.org/network/1216932.CM240_3063Reverse rubrerythrin-2; Rubrerythrin (Rr), found in anaerobic sulphate-reducing bacteria, is a fusion protein containing an N-terminal diiron-binding domain and a C-terminal domain homologous to [...]
CDM70181.1 protein networkhttps://string-db.org/network/1216932.CM240_3064Penicillin-binding protein transpeptidase; This entry represents a beta-lactamase structural motif, which contins a cluster of alpha-helices and an alpha/beta sandwich. In addition to beta-lactam [...]
CDM70182.1 protein networkhttps://string-db.org/network/1216932.CM240_3065Putative membrane protein.
CDM70183.1 protein networkhttps://string-db.org/network/1216932.CM240_3066Hypothetical protein; Family membership.
CDM70184.1 protein networkhttps://string-db.org/network/1216932.CM240_3067Flavodoxins [1,E1] are electron-transfer proteins that function in various electron transport systems. Flavodoxins bind one FMN molecule, which serves as a redox-active prosthetic group. Flavodox [...]
CDM70185.1 protein networkhttps://string-db.org/network/1216932.CM240_3068Putative membrane protein; High confidence in function and specificity.
CDM70186.1 protein networkhttps://string-db.org/network/1216932.CM240_3069Membrane-bound protein LytR; This family appears at the C-terminus of members of the LytR_cpsA_psr, PF03816 family; Family membership.
CDM70187.1 protein networkhttps://string-db.org/network/1216932.CM240_3070Type 12 methyltransferase; High confidence in function and specificity.
CDM70188.1 protein networkhttps://string-db.org/network/1216932.CM240_3071Hypothetical protein; High confidence in function and specificity.
CDM70189.1 protein networkhttps://string-db.org/network/1216932.CM240_3072Hypothetical protein; High confidence in function and specificity.
CDM70190.1 protein networkhttps://string-db.org/network/1216932.CM240_3073Putative RNA-splicing ligase; This family of RNA ligases (join 2',3'-cyclic phosphate and 5'-OH ends. They catalyse the splicing of tRNA and may also participate in tRNA repair and recovery from [...]
CDM70191.1 protein networkhttps://string-db.org/network/1216932.CM240_3074Hypothetical protein; Family membership.
CDM70192.1 protein networkhttps://string-db.org/network/1216932.CM240_3075Putative membrane protein.
CDM70193.1 protein networkhttps://string-db.org/network/1216932.CM240_3076Hypothetical protein; High confidence in function and specificity.
CDM70194.1 protein networkhttps://string-db.org/network/1216932.CM240_3077Sensor histidine kinase; A two-component regulatory system serve as a basic stimulus-response coupling mechanism to allow organisms to sense and respond to changes in many different environmental [...]
CDM70195.1 protein networkhttps://string-db.org/network/1216932.CM240_3078Two-component response regulator; Two-component signal transduction systems enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; High co [...]
CDM70196.1 protein networkhttps://string-db.org/network/1216932.CM240_3079Putative ABC transporter, permease protein; This domain is found in predicted permeases and hypothetical transmembrane proteins; Family membership.
CDM70197.1 protein networkhttps://string-db.org/network/1216932.CM240_3080ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM70198.1 protein networkhttps://string-db.org/network/1216932.CM240_3081Hypothetical protein; High confidence in function and specificity.
CDM70199.1 protein networkhttps://string-db.org/network/1216932.CM240_3082Hypothetical protein; Family membership.
CDM70200.1 protein networkhttps://string-db.org/network/1216932.CM240_3083Amidase; The domain is named after the acronym cysteine,histidine-dependent amidohydrolases/peptidases. Many of these proteins are uncharacterised, but it has been proposed that they may function [...]
CDM70201.1 protein networkhttps://string-db.org/network/1216932.CM240_3084Hypothetical protein; Family membership.
CDM70202.1 protein networkhttps://string-db.org/network/1216932.CM240_3085Hypothetical protein; Family membership.
CDM70203.1 protein networkhttps://string-db.org/network/1216932.CM240_3086Hypothetical protein; Family membership.
CDM70204.1 protein networkhttps://string-db.org/network/1216932.CM240_3087ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM70205.1 protein networkhttps://string-db.org/network/1216932.CM240_3088ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM70206.1 protein networkhttps://string-db.org/network/1216932.CM240_3089Transcriptional regulator, MarR family; The marR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 135 amino acids present in transcription regulators of the marR/s [...]
CDM70207.1 protein networkhttps://string-db.org/network/1216932.CM240_3090Putative acetyltransferase, gnat family; The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various f [...]
CDM70208.1 protein networkhttps://string-db.org/network/1216932.CM240_3091The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions from bacterial antibiotic resist [...]
CDM70209.1 protein networkhttps://string-db.org/network/1216932.CM240_3092Hypothetical protein.
CDM70210.1 protein networkhttps://string-db.org/network/1216932.CM240_3093Hypothetical protein; Family membership.
CDM70211.1 protein networkhttps://string-db.org/network/1216932.CM240_3094Transcriptional regulator, MerR family; The merR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 70 residues present in the merR family of transcriptional regulat [...]
CDM70212.1 protein networkhttps://string-db.org/network/1216932.CM240_3095Hypothetical protein; Family membership.
CDM70213.1 protein networkhttps://string-db.org/network/1216932.CM240_3096Putative oxidoreductase; High confidence in function and specificity.
CDM70214.1 protein networkhttps://string-db.org/network/1216932.CM240_3097Oxidoreductase, FAD-binding; This entry includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase,Sarcosine oxidase beta subunit, D-alanine oxidase,D-aspartate oxidase; H [...]
CDM70215.1 protein networkhttps://string-db.org/network/1216932.CM240_3098Exported membrane protein; EamA (named after the O-acetyl-serine/cysteine export gene in E. coli) is a protein domain found in a wide range of proteins including the Erwinia chrysanthemi PecM pro [...]
CDM70216.1 protein networkhttps://string-db.org/network/1216932.CM240_3099Hypothetical protein; Family membership.
CDM70217.1 protein networkhttps://string-db.org/network/1216932.CM240_3100Hypothetical protein; Family membership.
CDM70218.1 protein networkhttps://string-db.org/network/1216932.CM240_3101Hypothetical protein; Family membership.
CDM70219.1 protein networkhttps://string-db.org/network/1216932.CM240_3102Putative membrane protein.
CDM70220.1 protein networkhttps://string-db.org/network/1216932.CM240_3103ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM70221.1 protein networkhttps://string-db.org/network/1216932.CM240_3104Transcriptional regulator, GntR family; The gntR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 60-70 residues present in transcriptional regulators of the gntR [...]
CDM70222.1 protein networkhttps://string-db.org/network/1216932.CM240_3105AraC-family transcriptional regulator; araC, the arabinose operon regulatory protein,which activates the transcription of the araBAD genes; Family membership.
CDM70223.1 protein networkhttps://string-db.org/network/1216932.CM240_3106Hypothetical protein; High confidence in function and specificity.
CDM70224.1 protein networkhttps://string-db.org/network/1216932.CM240_3107Hypothetical protein; Family membership.
CDM70225.1 protein networkhttps://string-db.org/network/1216932.CM240_3108Hypothetical protein; High confidence in function and specificity.
CDM70226.1 protein networkhttps://string-db.org/network/1216932.CM240_3109The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions from bacterial antibiotic resist [...]
CDM70227.1 protein networkhttps://string-db.org/network/1216932.CM240_3110Hypothetical protein; High confidence in function and specificity.
CDM70228.1 protein networkhttps://string-db.org/network/1216932.CM240_3111MerR family transcriptional regulator; The merR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 70 residues present in the merR family of transcriptional regulato [...]
CDM70229.1 protein networkhttps://string-db.org/network/1216932.CM240_3112Putative drug resistance ABC-transporter,membrane protein; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological im [...]
CDM70230.1 protein networkhttps://string-db.org/network/1216932.CM240_3113ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters; High confidence in function and specificity.
CDM70231.1 protein networkhttps://string-db.org/network/1216932.CM240_3114Hypothetical protein; High confidence in function and specificity.
CDM70232.1 protein networkhttps://string-db.org/network/1216932.CM240_3115Hypothetical protein; High confidence in function and specificity.
CDM70233.1 protein networkhttps://string-db.org/network/1216932.CM240_3116Hypothetical protein; Family membership.
CDM70234.1 protein networkhttps://string-db.org/network/1216932.CM240_3117Putative membrane protein.
CDM70235.1 protein networkhttps://string-db.org/network/1216932.CM240_3118Peptidyl-prolyl cis-trans isomerase (PPIase or rotamase) is an enzyme that accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. [...]
CDM70236.1 protein networkhttps://string-db.org/network/1216932.CM240_3119This model describes NifB, a protein required for the biosynthesis of the iron-molybdenum (or iron-vanadium) cofactor used by the nitrogen-fixing enzyme nitrogenase. NifB belongs to the radical S [...]
nifE protein networkhttps://string-db.org/network/1216932.CM240_3120Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE; The enzyme responsible for nitrogen fixation, the nitrogenase, shows a high degree of conservation of structure, function, and amin [...]
nifK protein networkhttps://string-db.org/network/1216932.CM240_3121Nitrogenase molybdenum-iron protein beta chain; All known Mo-nitrogenases consist of two components,component I (also called dinitrogenase, or Fe-Mo protein),an alpha2beta2 tetramer encoded by th [...]
nifD protein networkhttps://string-db.org/network/1216932.CM240_3122Nitrogenase molybdenum-iron protein alpha chain; High confidence in function and specificity.
CDM70240.1 protein networkhttps://string-db.org/network/1216932.CM240_3123Nitrogen regulatory protein P-II; P-II modulates the activity of glutamine synthetase; High confidence in function and specificity; Belongs to the P(II) protein family.
CDM70241.1 protein networkhttps://string-db.org/network/1216932.CM240_3124Nitrogen regulatory protein P-II; P-II modulates the activity of glutamine synthetase; High confidence in function and specificity.
nifH5 protein networkhttps://string-db.org/network/1216932.CM240_3125Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belo [...]
CDM70243.1 protein networkhttps://string-db.org/network/1216932.CM240_3126Molybdate-binding protein; This entry represents members of the periplasmic binding domain superfamily.It is often associated with a helix-turn-helix domain; High confidence in function and speci [...]
CDM70244.1 protein networkhttps://string-db.org/network/1216932.CM240_3127Hypothetical protein; High confidence in function and specificity.
CDM70245.1 protein networkhttps://string-db.org/network/1216932.CM240_3128Hypothetical protein; High confidence in function and specificity.
nifV-ALPHA protein networkhttps://string-db.org/network/1216932.CM240_3129Homocitrate synthase (gene nifV) which is involved in the biosynthesis of the iron-molybdenum cofactor of nitrogenase and catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate into hom [...]
CDM70247.1 protein networkhttps://string-db.org/network/1216932.CM240_3130Hypothetical protein; High confidence in function and specificity.
modA protein networkhttps://string-db.org/network/1216932.CM240_3131Molybdate ABC transporter, periplasmic molybdate-binding protein; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily, which uses the hydrolysis of ATP to energise diverse biolo [...]
modB protein networkhttps://string-db.org/network/1216932.CM240_3132Molybdate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane [...]
CDM70250.1 protein networkhttps://string-db.org/network/1216932.CM240_3133ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM70251.1 protein networkhttps://string-db.org/network/1216932.CM240_3134Cation-transporting ATPase; Members of this families are involved in Na+/K+,H+/K+, Ca++ and Mg++ transport. This family represents 5 transmembrane helices; High confidence in function and specifi [...]
CDM70252.1 protein networkhttps://string-db.org/network/1216932.CM240_3135Glycosyl transferase, family 2; High confidence in function and specificity.
CDM70253.1 protein networkhttps://string-db.org/network/1216932.CM240_3136Hypothetical protein; Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Family membership.
CDM70254.1 protein networkhttps://string-db.org/network/1216932.CM240_3137Putative protein; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to [...]
CDM70255.1 protein networkhttps://string-db.org/network/1216932.CM240_3138Hypothetical protein; High confidence in function and specificity.
CDM70256.1 protein networkhttps://string-db.org/network/1216932.CM240_3139Hypothetical protein; Family membership.
CDM70257.1 protein networkhttps://string-db.org/network/1216932.CM240_3140Hypothetical protein; Family membership.
CDM70258.1 protein networkhttps://string-db.org/network/1216932.CM240_3141Transcriptional regulator, TetR family; This entry represents a DNA-binding domain with a helix-turn-helix (HTH) structure that is found in several bacterial and archaeal transcriptional regulato [...]
CDM70259.1 protein networkhttps://string-db.org/network/1216932.CM240_3142Hypothetical protein; High confidence in function and specificity.
CDM70260.1 protein networkhttps://string-db.org/network/1216932.CM240_3143Histidine kinase; A two-component regulatory system serve as a basic stimulus-response coupling mechanism to allow organisms to sense and respond to changes in many different environmental condit [...]
ykoG protein networkhttps://string-db.org/network/1216932.CM240_3144Two component transcriptional regulator, winged helix family; Two-component signal transduction systems enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, an [...]
CDM70262.1 protein networkhttps://string-db.org/network/1216932.CM240_3145Hypothetical protein; Family membership.
CDM70263.1 protein networkhttps://string-db.org/network/1216932.CM240_3146Hypothetical protein; High confidence in function and specificity.
CDM70264.1 protein networkhttps://string-db.org/network/1216932.CM240_3147Hypothetical protein; Family membership.
CDM70265.1 protein networkhttps://string-db.org/network/1216932.CM240_3148Hypothetical protein; Family membership.
CDM70266.1 protein networkhttps://string-db.org/network/1216932.CM240_3149Hypothetical protein.
CDM70268.1 protein networkhttps://string-db.org/network/1216932.CM240_3151Hypothetical protein; High confidence in function and specificity.
CDM70269.1 protein networkhttps://string-db.org/network/1216932.CM240_3152Pectate lyase is an enzyme involved in the maceration and soft rotting of plant tissue. Pectate lyase is responsible for the eliminative cleavage of pectate,yielding oligosaccharides with 4-deoxy [...]
CDM70270.1 protein networkhttps://string-db.org/network/1216932.CM240_3153Hypothetical protein; Family membership.
CDM70271.1 protein networkhttps://string-db.org/network/1216932.CM240_3154MATE efflux family protein; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range of cati [...]
CDM70273.1 protein networkhttps://string-db.org/network/1216932.CM240_3156Putative metallophosphoesterase; Members of this family are part of the Calcineurin-like phosphoesterase superfamily; Family membership.
CDM70274.1 protein networkhttps://string-db.org/network/1216932.CM240_3157Dihydrofolate reductase family protein; This domain is found in the C terminus of the bifunctional deaminase-reductase of Escherichia coli,Bacillus subtilis and other bacteria in combination with [...]
CDM70275.1 protein networkhttps://string-db.org/network/1216932.CM240_3158Hypothetical protein; High confidence in function and specificity.
CDM70276.1 protein networkhttps://string-db.org/network/1216932.CM240_3159Members of this family are transcriptional regulators that appear to be related to the PF01047 family. This family includes PadR Q9EXE6 a protein that is involved in negative regulation of phenol [...]
CDM70277.1 protein networkhttps://string-db.org/network/1216932.CM240_3160Hypothetical protein; High confidence in function and specificity.
CDM70278.1 protein networkhttps://string-db.org/network/1216932.CM240_3161Hypothetical protein; Family membership.
CDM70279.1 protein networkhttps://string-db.org/network/1216932.CM240_3162Aminoglycoside phosphotransferase; This entry consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include:-aminoglycoside 3'-phosphotrans [...]
CDM70280.1 protein networkhttps://string-db.org/network/1216932.CM240_3163Hypothetical protein.
CDM70281.1 protein networkhttps://string-db.org/network/1216932.CM240_3164Hypothetical protein; Family membership.
CDM70282.1 protein networkhttps://string-db.org/network/1216932.CM240_3165Acetyltransferase, GNAT family; The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions [...]
CDM70283.1 protein networkhttps://string-db.org/network/1216932.CM240_3166ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diver [...]
CDM70284.1 protein networkhttps://string-db.org/network/1216932.CM240_3167ABC transporter permease; High confidence in function and specificity.
CDM70285.1 protein networkhttps://string-db.org/network/1216932.CM240_3168ABC transporter, substrate-binding protein,aliphatic sulphonates; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; High c [...]
CDM70286.1 protein networkhttps://string-db.org/network/1216932.CM240_3169Nitrogen regulatory protein PII; P-II modulates the activity of glutamine synthetase; Hypothetical protein.
CDM70287.1 protein networkhttps://string-db.org/network/1216932.CM240_3170Nitrogen regulatory protein PII; P-II modulates the activity of glutamine synthetase; Family membership.
CDM70288.1 protein networkhttps://string-db.org/network/1216932.CM240_3171Allophanate hydrolase catalyses the second reaction in an ATP-dependent, two-step degradation of urea to ammonia and C02. This follows the action of the biotin-containing urea carboxylase. In bac [...]
DUR1,2 protein networkhttps://string-db.org/network/1216932.CM240_3172Hydrolysis of urea to ammonia and CO2; High confidence in function and specificity.
CDM70290.1 protein networkhttps://string-db.org/network/1216932.CM240_3173Urea carboxylase; A number of bacteria utilise urea as a nitrogen source by the urea carboxylase/allophanate hydrolase pathway, which uses biotin and consumes ATP, rather than by means of the nic [...]
CDM70291.1 protein networkhttps://string-db.org/network/1216932.CM240_3174Urea carboxylase; This family of proteins are functionally uncharacterised; High confidence in function and specificity.
CDM70292.1 protein networkhttps://string-db.org/network/1216932.CM240_3175Hypothetical protein; High confidence in function and specificity.
CDM70293.1 protein networkhttps://string-db.org/network/1216932.CM240_3176The cold-shock domain (CSD) is a protein domain of about 70 amino acids which has been found in prokaryotic and eukaryotic DNA-binding proteins.[1][2][3] Part of this domain is highly; Family mem [...]
CDM70294.1 protein networkhttps://string-db.org/network/1216932.CM240_3177Hypothetical protein; Family membership.
CDM70295.1 protein networkhttps://string-db.org/network/1216932.CM240_3178Hypothetical protein.
CDM70296.1 protein networkhttps://string-db.org/network/1216932.CM240_3179Putative membrane protein.
fldI2 protein networkhttps://string-db.org/network/1216932.CM240_3180Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; High confidence in function and specificity.
CDM70298.1 protein networkhttps://string-db.org/network/1216932.CM240_31812-hydroxyglutaryl-CoA dehydratase subunit D; Degradation of glutamate via the hydroxyglutarate pathway involves the syn-elimination of water from 2-hydroxyglutaryl-CoA. This anaerobic process is [...]
CDM70299.1 protein networkhttps://string-db.org/network/1216932.CM240_3182Polyferredoxin [Energy production and conversion]; Family membership.
CDM70300.1 protein networkhttps://string-db.org/network/1216932.CM240_3183Hypothetical protein; Family membership.
CDM70301.1 protein networkhttps://string-db.org/network/1216932.CM240_3184Hypothetical protein.
CDM70303.1 protein networkhttps://string-db.org/network/1216932.CM240_3186Hypothetical protein.
CDM70304.1 protein networkhttps://string-db.org/network/1216932.CM240_3187Hypothetical protein; Frameshift; Family membership.
catB protein networkhttps://string-db.org/network/1216932.CM240_3188Chloramphenicol acetyltransferase; This enzyme is an effector of chloramphenicol resistance in bacteria; Belongs to the chloramphenicol acetyltransferase family.
CDM70306.1 protein networkhttps://string-db.org/network/1216932.CM240_3189Hypothetical protein; Family membership.
CDM70307.1 protein networkhttps://string-db.org/network/1216932.CM240_3190Putative membrane protein; Family membership.
CDM70308.1 protein networkhttps://string-db.org/network/1216932.CM240_3191Hypothetical protein; Family membership.
CDM70309.1 protein networkhttps://string-db.org/network/1216932.CM240_3192Hypothetical protein; High confidence in function and specificity.
CDM70310.1 protein networkhttps://string-db.org/network/1216932.CM240_3193Hypothetical protein.
CDM70311.1 protein networkhttps://string-db.org/network/1216932.CM240_3194Oxidoreductase; This family of enzymes utilise NADP or NAD. This family is called the GFO/IDH/MOCA family in swiss-prot; High confidence in function and specificity.
CDM70312.1 protein networkhttps://string-db.org/network/1216932.CM240_3195Radical SAM domain protein; Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine; High confidence in function and specificity.
CDM70313.1 protein networkhttps://string-db.org/network/1216932.CM240_3196Hypothetical protein; High confidence in function and specificity.
CDM70314.1 protein networkhttps://string-db.org/network/1216932.CM240_3197Hypothetical protein; High confidence in function and specificity.
CDM70315.1 protein networkhttps://string-db.org/network/1216932.CM240_3198Hypothetical protein.
CDM70316.1 protein networkhttps://string-db.org/network/1216932.CM240_3199Hypothetical protein; Family membership.
CDM70317.1 protein networkhttps://string-db.org/network/1216932.CM240_3200Family 2 glycosyl transferase; The biosynthesis of disaccharides, oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse th [...]
CDM70318.1 protein networkhttps://string-db.org/network/1216932.CM240_3201Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC m [...]
CDM70319.1 protein networkhttps://string-db.org/network/1216932.CM240_3202ABC-type multidrug transport system; ABC transporter transmembrane domain is main transmembrane structural unit of ATP-binding cassette transporter which consist of six transmembrane domaines. Ma [...]
CDM70320.1 protein networkhttps://string-db.org/network/1216932.CM240_3203ABC transporter transmembrane domain is main transmembrane structural unit of ATP-binding cassette transporter which consist of six transmembrane domaines. Many members of the ABC transporter fam [...]
celA1 protein networkhttps://string-db.org/network/1216932.CM240_3204High confidence in function and specificity; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CDM70322.1 protein networkhttps://string-db.org/network/1216932.CM240_3205HAD-superfamily hydrolase; The haloacid dehydrogenase superfamily (HAD superfamily) includes phosphatases, phosphonatases, P-type ATPases, beta-phosphoglucomutases, phosphomannomutases,and dehalo [...]
CDM70323.1 protein networkhttps://string-db.org/network/1216932.CM240_3206Hypothetical protein; Family membership.
CDM70324.1 protein networkhttps://string-db.org/network/1216932.CM240_3207DegV family protein; The structure of this protein revealed a bound fatty-acid molecule in a pocket between the two protein domains. The structure indicates that this family has the molecular fun [...]
rluF-2 protein networkhttps://string-db.org/network/1216932.CM240_3208Ribosomal large subunit pseudouridine synthase; Belongs to the pseudouridine synthase rsuA family; High confidence in function and specificity.
CDM70326.1 protein networkhttps://string-db.org/network/1216932.CM240_3209Hypothetical protein; Family membership.
yybG protein networkhttps://string-db.org/network/1216932.CM240_3210Pentapeptide repeats are a family of sequence motifs found in multiple tandem copies in protein molecules.[2][3] Pentapeptide repeat proteins are found in all species, but they are found in many [...]
CDM70328.1 protein networkhttps://string-db.org/network/1216932.CM240_3211Putative membrane protein; High confidence in function and specificity.
CDM70329.1 protein networkhttps://string-db.org/network/1216932.CM240_3212Hypothetical protein; High confidence in function and specificity.
CDM70330.1 protein networkhttps://string-db.org/network/1216932.CM240_3213Hypothetical protein; High confidence in function and specificity.
CDM70331.1 protein networkhttps://string-db.org/network/1216932.CM240_3214Hypothetical protein; High confidence in function and specificity.
CDM70332.1 protein networkhttps://string-db.org/network/1216932.CM240_3215Flavodoxin; This domain is found in a number of proteins including flavodoxin and nitric-oxide synthase. Flavodoxins are electron-transfer proteins that function in various electron transport sys [...]
CDM70333.1 protein networkhttps://string-db.org/network/1216932.CM240_3216Iron-dependent transcriptional regulator; The iron dependent repressors are a family of bacterial and archaeal transcriptional repressors. At their N-terminus they contain a dtxR-type HTH domain. [...]
CDM70334.1 protein networkhttps://string-db.org/network/1216932.CM240_3217Zinc/iron permease; High confidence in function and specificity.
CDM70335.1 protein networkhttps://string-db.org/network/1216932.CM240_3218Hypothetical protein; Family membership.
CDM70336.1 protein networkhttps://string-db.org/network/1216932.CM240_3219DegV family protein; High confidence in function and specificity.
CDM70337.1 protein networkhttps://string-db.org/network/1216932.CM240_3220Hypothetical protein; High confidence in function and specificity.
CDM70338.1 protein networkhttps://string-db.org/network/1216932.CM240_3221Flavodoxin; This domain is found in a number of proteins including flavodoxin and nitric-oxide synthase. Flavodoxins are electron-transfer proteins that function in various electron transport sys [...]
CDM70339.1 protein networkhttps://string-db.org/network/1216932.CM240_3222Putative membrane protein.
CDM70340.1 protein networkhttps://string-db.org/network/1216932.CM240_3223Hypothetical protein.
dinB-2 protein networkhttps://string-db.org/network/1216932.CM240_3224Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. [...]
CDM70342.1 protein networkhttps://string-db.org/network/1216932.CM240_3225Hypothetical protein.
CDM70343.1 protein networkhttps://string-db.org/network/1216932.CM240_3226Hypothetical protein.
CDM70344.1 protein networkhttps://string-db.org/network/1216932.CM240_3227Mate efflux family protein; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range of cati [...]
CDM70345.1 protein networkhttps://string-db.org/network/1216932.CM240_3228Arsenate reductase family protein; This family describes the well-studied thioredoxin-dependent arsenate reductase of Staphylococcus aureaus plasmid pI258 and other mechanistically similar arsena [...]
CDM70346.1 protein networkhttps://string-db.org/network/1216932.CM240_3229Putative arsenical resistance operon repressor ArsR; The arsR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 90-100 amino acids present in transcription regulato [...]
CDM70347.1 protein networkhttps://string-db.org/network/1216932.CM240_3230The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions from bacterial antibiotic resist [...]
ydeE protein networkhttps://string-db.org/network/1216932.CM240_3231Transcriptional regulator, AraC family; araC, the arabinose operon regulatory protein,which activates the transcription of the araBAD genes; High confidence in function and specificity.
CDM70349.1 protein networkhttps://string-db.org/network/1216932.CM240_3232Putative membrane protein.
CDM70350.1 protein networkhttps://string-db.org/network/1216932.CM240_3233Hypothetical protein; High confidence in function and specificity.
CDM70351.1 protein networkhttps://string-db.org/network/1216932.CM240_3234Putative protein; High confidence in function and specificity.
CDM70352.1 protein networkhttps://string-db.org/network/1216932.CM240_3235Hypothetical protein; Family membership.
CDM70353.1 protein networkhttps://string-db.org/network/1216932.CM240_3236Hypothetical protein; High confidence in function and specificity.
CDM70354.1 protein networkhttps://string-db.org/network/1216932.CM240_3237Hypothetical protein; High confidence in function and specificity.
CDM70355.1 protein networkhttps://string-db.org/network/1216932.CM240_3238ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters; High confidence in function and specificity.
cbiQ protein networkhttps://string-db.org/network/1216932.CM240_3239Cobalt ABC transporter permease CbiQ; This family consists of various cobalt transport proteins Most of which are found in Cobalamin (Vitamin B12) biosynthesis operons. In Salmonella the cbiN cbi [...]
CDM70357.1 protein networkhttps://string-db.org/network/1216932.CM240_3240Putative ABC transporter ATP-binding protein MA_0394; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
cbiM protein networkhttps://string-db.org/network/1216932.CM240_3241Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
cbiN protein networkhttps://string-db.org/network/1216932.CM240_3242Cobalt transport protein CbiN; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.
rodA protein networkhttps://string-db.org/network/1216932.CM240_3243Rod shape-determining protein rodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
CDM70361.1 protein networkhttps://string-db.org/network/1216932.CM240_3244Putative membrane protein.
CDM70362.1 protein networkhttps://string-db.org/network/1216932.CM240_3245Hypothetical protein; Family membership.
CDM70363.1 protein networkhttps://string-db.org/network/1216932.CM240_3246Putative membrane protein.
CDM70364.1 protein networkhttps://string-db.org/network/1216932.CM240_3247Hypothetical protein; Family membership.
CDM70365.1 protein networkhttps://string-db.org/network/1216932.CM240_3248Hypothetical protein; Family membership.
CDM70366.1 protein networkhttps://string-db.org/network/1216932.CM240_3249Transposase proteins are necessary for efficient DNA transposition. This family includes the bacterial insertion sequence (IS) element, IS66, from Agrobacterium tumefaciens. IS66 may cause geneti [...]
CDM70367.1 protein networkhttps://string-db.org/network/1216932.CM240_3250Putative membrane protein.
CDM70369.1 protein networkhttps://string-db.org/network/1216932.CM240_3252Hypothetical protein; Family membership.
CDM70370.1 protein networkhttps://string-db.org/network/1216932.CM240_3253Phage holins and lytic enzymes are both necessary for bacterial lysis and virus dissemination.This family also includes TcdE/UtxA involved in toxin secretion in Clostridium difficile; Hypothetica [...]
agrA-2 protein networkhttps://string-db.org/network/1216932.CM240_3254Accessory gene regulator protein A; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine protein [...]
CDM70372.1 protein networkhttps://string-db.org/network/1216932.CM240_3255Hypothetical protein.
CDM70373.1 protein networkhttps://string-db.org/network/1216932.CM240_3256Putative accessory gene regulator protein; May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor; Belongs to the AgrB family.
CDM70374.1 protein networkhttps://string-db.org/network/1216932.CM240_3257Putative membrane protein; Family membership.
CDM70376.1 protein networkhttps://string-db.org/network/1216932.CM240_3259Hypothetical protein.
CDM70377.1 protein networkhttps://string-db.org/network/1216932.CM240_3260Hypothetical protein; Family membership; Belongs to the sigma-70 factor family.
CDM70378.1 protein networkhttps://string-db.org/network/1216932.CM240_3261Hypothetical protein; Family membership.
xerC protein networkhttps://string-db.org/network/1216932.CM240_3262Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chro [...]
CDM70381.1 protein networkhttps://string-db.org/network/1216932.CM240_3264Putative membrane protein.
CDM70382.1 protein networkhttps://string-db.org/network/1216932.CM240_3265Putative mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; Glycoside hydrolase family 73 is a family of glycoside hydrolases.Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes [...]
CDM70383.1 protein networkhttps://string-db.org/network/1216932.CM240_3266Putative membrane protein.
CDM70384.1 protein networkhttps://string-db.org/network/1216932.CM240_3267Putative membrane protein.
CDM70387.1 protein networkhttps://string-db.org/network/1216932.CM240_3270Hypothetical protein; Family membership.
CDM70389.1 protein networkhttps://string-db.org/network/1216932.CM240_3272Hypothetical protein.
CDM70390.1 protein networkhttps://string-db.org/network/1216932.CM240_3273Hypothetical protein; Family membership.
CDM70391.1 protein networkhttps://string-db.org/network/1216932.CM240_3274Hypothetical protein.
CDM70392.1 protein networkhttps://string-db.org/network/1216932.CM240_3275NADPH-dependent FMN reductase reduces FMN and also reduces riboflavin and FAD, although more slowly. Members of this entry catalyse the reaction NAD(P)H + FMN = NAD(P)(+) + FMNH(2); High confiden [...]
CDM70393.1 protein networkhttps://string-db.org/network/1216932.CM240_3276This family appears to be have methyltransferase activity; High confidence in function and specificity.
CDM70394.1 protein networkhttps://string-db.org/network/1216932.CM240_3277Methyltransferase domain; Members of this family are SAM dependent methyltransferases; High confidence in function and specificity.
CDM70395.1 protein networkhttps://string-db.org/network/1216932.CM240_3278Acetyltransferase (GNAT) family; Acetyltransferase (or transacetylase) is a type of transferase enzyme that transfers an acetyl group; Family membership.
recA-2 protein networkhttps://string-db.org/network/1216932.CM240_3279Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of hom [...]
ManA protein networkhttps://string-db.org/network/1216932.CM240_3280This is a family of bacterial glycoside hydrolases formerly known as cellulase family J, and now known as Cel44A. It is one of the major enzymatic components of the cellulosome of Clostridium the [...]
CDM70398.1 protein networkhttps://string-db.org/network/1216932.CM240_3281PKD domain containing protein; Gycoside hydrolase family 44 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bon [...]
CDM70399.1 protein networkhttps://string-db.org/network/1216932.CM240_3282Hypothetical protein; Frameshift; High confidence in function and specificity.
CDM70400.1 protein networkhttps://string-db.org/network/1216932.CM240_3283Transposase; The helix-turn-helix (HTH) is a major structural motif capable of binding DNA. It is composed of two alpha helices joined by a short strand of amino acids and is found in many protei [...]
CDM70401.1 protein networkhttps://string-db.org/network/1216932.CM240_3284Putative transposase; Involved in the transposition of the insertion sequence IS150; High confidence in function and specificity.
CDM70402.1 protein networkhttps://string-db.org/network/1216932.CM240_3285Hypothetical protein.
CDM70403.1 protein networkhttps://string-db.org/network/1216932.CM240_3286Hypothetical protein; High confidence in function and specificity.
CDM70404.1 protein networkhttps://string-db.org/network/1216932.CM240_3287Hypothetical protein; High confidence in function and specificity.
CDM70405.1 protein networkhttps://string-db.org/network/1216932.CM240_3288Putative membrane protein; Family membership.
CDM70406.1 protein networkhttps://string-db.org/network/1216932.CM240_3289Putative membrane protein.
CDM70407.1 protein networkhttps://string-db.org/network/1216932.CM240_3290ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters; Family membership.
CDM70408.1 protein networkhttps://string-db.org/network/1216932.CM240_3291Hypothetical protein; Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine protein kinase (HK) an [...]
CDM70409.1 protein networkhttps://string-db.org/network/1216932.CM240_3292Sensor Kinase; Family membership.
CDM70410.1 protein networkhttps://string-db.org/network/1216932.CM240_3293Hypothetical protein; Family membership.
CDM70411.1 protein networkhttps://string-db.org/network/1216932.CM240_3294Hypothetical protein.
CDM70412.1 protein networkhttps://string-db.org/network/1216932.CM240_3295Hypothetical protein.
CDM70413.1 protein networkhttps://string-db.org/network/1216932.CM240_3296ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM70414.1 protein networkhttps://string-db.org/network/1216932.CM240_3297Hypothetical protein; Family membership.
CDM70415.1 protein networkhttps://string-db.org/network/1216932.CM240_3298Hypothetical protein; Family membership.
CDM70416.1 protein networkhttps://string-db.org/network/1216932.CM240_3299Putative membrane protein.
CDM70417.1 protein networkhttps://string-db.org/network/1216932.CM240_3300ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological systems. ABC transporters are minimally constituted of two co [...]
CDM70418.1 protein networkhttps://string-db.org/network/1216932.CM240_3301Hypothetical protein; Family membership.
CDM70419.1 protein networkhttps://string-db.org/network/1216932.CM240_3302Hypothetical protein; Family membership.
CDM70420.1 protein networkhttps://string-db.org/network/1216932.CM240_3303Hypothetical protein; Family membership.
CDM70421.1 protein networkhttps://string-db.org/network/1216932.CM240_3304Hypothetical protein; Family membership.
CDM70422.1 protein networkhttps://string-db.org/network/1216932.CM240_3305Hypothetical protein.
CDM70423.1 protein networkhttps://string-db.org/network/1216932.CM240_3306Transposase proteins are necessary for efficient DNA transposition. This family includes the bacterial insertion sequence (IS) element, IS66, from Agrobacterium tumefaciens. IS66 may cause geneti [...]
CDM70424.1 protein networkhttps://string-db.org/network/1216932.CM240_3307Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Family membership.
CDM70425.1 protein networkhttps://string-db.org/network/1216932.CM240_3308Hypothetical protein; Family membership.
CDM70426.1 protein networkhttps://string-db.org/network/1216932.CM240_3309Hypothetical protein; Frameshift; High confidence in function and specificity.
CDM70427.1 protein networkhttps://string-db.org/network/1216932.CM240_3310Hypothetical protein; Frameshift; High confidence in function and specificity.
CDM70428.1 protein networkhttps://string-db.org/network/1216932.CM240_3311Hypothetical protein; Frameshift.
CDM70429.1 protein networkhttps://string-db.org/network/1216932.CM240_3312Hypothetical protein.
CDM70430.1 protein networkhttps://string-db.org/network/1216932.CM240_3313Hypothetical protein.
CDM70431.1 protein networkhttps://string-db.org/network/1216932.CM240_3314Hypothetical protein; High confidence in function and specificity.
CDM70432.1 protein networkhttps://string-db.org/network/1216932.CM240_3315Hypothetical protein; Family membership; Belongs to the glycosyl hydrolase 13 family.
CDM70433.1 protein networkhttps://string-db.org/network/1216932.CM240_3316Glycoside hydrolase family 25 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohyd [...]
CDM70434.1 protein networkhttps://string-db.org/network/1216932.CM240_3317Hypothetical protein.
CDM70435.1 protein networkhttps://string-db.org/network/1216932.CM240_3318Putative membrane protein; Family membership.
CDM70436.1 protein networkhttps://string-db.org/network/1216932.CM240_3319Hypothetical protein; Family membership.
CDM70437.1 protein networkhttps://string-db.org/network/1216932.CM240_3320Putative membrane protein.
CDM70438.1 protein networkhttps://string-db.org/network/1216932.CM240_3321Hypothetical protein.
CDM70439.1 protein networkhttps://string-db.org/network/1216932.CM240_3322Hypothetical protein.
CDM70440.1 protein networkhttps://string-db.org/network/1216932.CM240_3323Hypothetical protein; High confidence in function and specificity.
celK protein networkhttps://string-db.org/network/1216932.CM240_3324Hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains; High confidence in function and specificity; Belongs [...]
celA3 protein networkhttps://string-db.org/network/1216932.CM240_3325High confidence in function and specificity.
celA2 protein networkhttps://string-db.org/network/1216932.CM240_3326Endo-beta-mannanase; Family membership.
cipA protein networkhttps://string-db.org/network/1216932.CM240_3327Cellulosome anchoring protein CipA; Family membership.
xghA protein networkhttps://string-db.org/network/1216932.CM240_3328Xyloglucanase; High confidence in function and specificity.
CDM70446.1 protein networkhttps://string-db.org/network/1216932.CM240_3329N-acetyltransferases, the histone acetyltransferase domain of P300/CBP associating factor PCAF, the catalytic domain of GCN5 histone acetyltransferase, and diamine acetyltransferase; Conserved hy [...]
CDM70447.1 protein networkhttps://string-db.org/network/1216932.CM240_3330Hypothetical protein; Family membership.
CDM70448.1 protein networkhttps://string-db.org/network/1216932.CM240_3331Putative membrane protein.
CDM70449.1 protein networkhttps://string-db.org/network/1216932.CM240_3332Putative membrane protein.
CDM70450.1 protein networkhttps://string-db.org/network/1216932.CM240_3333Transcriptional regulator, AraC family; The helix-turn-helix (HTH) is a major structural motif capable of binding DNA. It is composed of two alpha helices joined by a short strand of amino acids [...]
CDM70451.1 protein networkhttps://string-db.org/network/1216932.CM240_3334Hypothetical protein; Frameshift; Family membership.
CDM70452.1 protein networkhttps://string-db.org/network/1216932.CM240_3335Hypothetical protein.
CDM70453.1 protein networkhttps://string-db.org/network/1216932.CM240_3336Putative threonine aldolase; This domain is found in many tryptophanases (tryptophan indole-lyase, TNase), tyrosine phenol-lyases (TPL) and threonine aldolases. It is involved in the degradation [...]
yhcH protein networkhttps://string-db.org/network/1216932.CM240_3337ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters; High confidence in function and specificity.
CDM70455.1 protein networkhttps://string-db.org/network/1216932.CM240_3338Putative membrane protein.
CDM70456.1 protein networkhttps://string-db.org/network/1216932.CM240_3339Putative membrane protein.
crcB protein networkhttps://string-db.org/network/1216932.CM240_3340Putative membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
CDM70458.1 protein networkhttps://string-db.org/network/1216932.CM240_3341Putative membrane protein.
CDM70459.1 protein networkhttps://string-db.org/network/1216932.CM240_3342ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; High confidence in function and specificity.
CDM70460.1 protein networkhttps://string-db.org/network/1216932.CM240_3343Hypothetical protein; Family membership.
CDM70461.1 protein networkhttps://string-db.org/network/1216932.CM240_3344Hypothetical protein; Family membership.
CDM70462.1 protein networkhttps://string-db.org/network/1216932.CM240_3345Hypothetical protein.
CDM70463.1 protein networkhttps://string-db.org/network/1216932.CM240_3346Hypothetical protein; Family membership.
CDM70464.1 protein networkhttps://string-db.org/network/1216932.CM240_3347Hypothetical protein; Family membership.
CDM70465.1 protein networkhttps://string-db.org/network/1216932.CM240_3348Heat shock protein 70; Prokaryotic and eukaryotic organisms respond to heat shock or other environmental stress by the induction of the synthesis of proteins collectively known as heat-shock prot [...]
CDM70466.1 protein networkhttps://string-db.org/network/1216932.CM240_3349Hypothetical protein; High confidence in function and specificity.
nnrD protein networkhttps://string-db.org/network/1216932.CM240_3350Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted [...]
CDM70468.1 protein networkhttps://string-db.org/network/1216932.CM240_3351Hypothetical protein; Family membership.
CDM70469.1 protein networkhttps://string-db.org/network/1216932.CM240_3352Hypothetical protein.
CDM70470.1 protein networkhttps://string-db.org/network/1216932.CM240_3353The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (P93115 and UDP-N-acetylglucosamine transferase (P74657). This N-terminal domain contains the acceptor binding sit [...]
CDM70471.1 protein networkhttps://string-db.org/network/1216932.CM240_3354DegV domain-containing protein CA_C3284; The structure of this protein revealed a bound fatty-acid molecule in a pocket between the two protein domains. The structure indicates that this family h [...]
CDM70472.1 protein networkhttps://string-db.org/network/1216932.CM240_3355Hypothetical protein; Frameshift; Family membership.
CDM70473.1 protein networkhttps://string-db.org/network/1216932.CM240_3356Hypothetical protein.
CDM70474.1 protein networkhttps://string-db.org/network/1216932.CM240_3357Putative secreted protein.
CDM70475.1 protein networkhttps://string-db.org/network/1216932.CM240_3358Putative membrane protein.
CDM70476.1 protein networkhttps://string-db.org/network/1216932.CM240_3359Hypothetical protein.
CDM70477.1 protein networkhttps://string-db.org/network/1216932.CM240_3360Hypothetical protein.
CDM70478.1 protein networkhttps://string-db.org/network/1216932.CM240_3361Putative membrane protein.
CDM70479.1 protein networkhttps://string-db.org/network/1216932.CM240_3362Acetyltransferase, GNAT family; The N-acetyltransferases (NAT) are enzymes that use acetyl coenzyme A (CoA) to transfer an acetyl group to a substrate, a reaction implicated in various functions [...]
CDM70480.1 protein networkhttps://string-db.org/network/1216932.CM240_3363TetR family transcriptional regulator; This entry represents a DNA-binding domain with a helix-turn-helix (HTH) structure that is found in several bacterial and archaeal transcriptional regulator [...]
CDM70481.1 protein networkhttps://string-db.org/network/1216932.CM240_3364Cyclomaltodextrinase; Glycoside hydrolase family 13 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond betwee [...]
CDM70482.1 protein networkhttps://string-db.org/network/1216932.CM240_3365Hypothetical protein; Family membership.
CDM70483.1 protein networkhttps://string-db.org/network/1216932.CM240_3366Transcriptional regulator; Family membership.
CDM70484.1 protein networkhttps://string-db.org/network/1216932.CM240_3367Hypothetical protein; Family membership.
CDM70485.1 protein networkhttps://string-db.org/network/1216932.CM240_3368Hypothetical protein; Family membership.
CDM70486.1 protein networkhttps://string-db.org/network/1216932.CM240_3369Transposase; The helix-turn-helix (HTH) is a major structural motif capable of binding DNA. It is composed of two alpha helices joined by a short strand of amino acids and is found in many protei [...]
CDM70487.1 protein networkhttps://string-db.org/network/1216932.CM240_3370Integrase, catalytic region; The retroviral integrase is the enzyme responsible for the insertion of a DNA copy of the viral genome into host DNA, an essential step in the replication cycle of vi [...]
CDM70488.1 protein networkhttps://string-db.org/network/1216932.CM240_3371Putative membrane protein.
CDM70489.1 protein networkhttps://string-db.org/network/1216932.CM240_3372Hypothetical protein; Family membership.
CDM70490.1 protein networkhttps://string-db.org/network/1216932.CM240_3373Putative membrane protein.
CDM70491.1 protein networkhttps://string-db.org/network/1216932.CM240_3374Hypothetical protein; High confidence in function and specificity.