| lgt protein network | https://string-db.org/network/1208920.CONE_0001 | Phosphatidylglycerol:prolipoprotein diacylglycerol transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of [...] |
| CONE_0002 protein network | https://string-db.org/network/1208920.CONE_0002 | Cell cycle control, cell division, chromosome partitioning; SecretomeP prediction: 0.07; Protein involved in cell division. |
| CONE_0003 protein network | https://string-db.org/network/1208920.CONE_0003 | Hypothetical protein; SecretomeP prediction: 0.19. |
| rppH protein network | https://string-db.org/network/1208920.CONE_0005 | (di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated [...] |
| proS protein network | https://string-db.org/network/1208920.CONE_0006 | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...] |
| CONE_0007 protein network | https://string-db.org/network/1208920.CONE_0007 | TolB protein; Intracellular trafficking and secretion; SecretomeP prediction: 0.09. |
| CONE_0008 protein network | https://string-db.org/network/1208920.CONE_0008 | Peptidoglycan-associated lipoprotein; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.23. |
| CONE_0009 protein network | https://string-db.org/network/1208920.CONE_0009 | Tol-pal system protein YbgF; Function unknown; SecretomeP prediction: 0.09; Protein involved in binding. |
| CONE_0010 protein network | https://string-db.org/network/1208920.CONE_0010 | Alpha/beta hydrolase fold protein; General function prediction only; SecretomeP prediction: 0.23; Protein involved in hydrolase activity. |
| gltS protein network | https://string-db.org/network/1208920.CONE_0013 | ESS family glutamate:Na+ symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family. |
| CONE_0014 protein network | https://string-db.org/network/1208920.CONE_0014 | TRAP-type transporter, periplasmic component; General function prediction only; SecretomeP prediction: 0.18. |
| dnaQ protein network | https://string-db.org/network/1208920.CONE_0015 | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing funct [...] |
| rnhA protein network | https://string-db.org/network/1208920.CONE_0016 | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. |
| gloB protein network | https://string-db.org/network/1208920.CONE_0017 | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. |
| CONE_0021 protein network | https://string-db.org/network/1208920.CONE_0021 | Membrane-bound lytic murein transglycosylase D; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.71; Protein involved in cell wall macromolecule catabolic process. |
| CONE_0022 protein network | https://string-db.org/network/1208920.CONE_0022 | Enoyl-[acyl-carrier protein] reductase I. |
| CONE_0025 protein network | https://string-db.org/network/1208920.CONE_0025 | Subfamily B ATP-binding cassette; Defense mechanisms; SecretomeP prediction: 0.31; Protein involved in transmembrane transport. |
| CONE_0026 protein network | https://string-db.org/network/1208920.CONE_0026 | Riboflavin synthase alpha chain; Coenzyme metabolism; SecretomeP prediction: 0.04; Protein involved in transferase activity. |
| CONE_0027 protein network | https://string-db.org/network/1208920.CONE_0027 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphat [...] |
| glyA protein network | https://string-db.org/network/1208920.CONE_0028 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major s [...] |
| tyrS protein network | https://string-db.org/network/1208920.CONE_0029 | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...] |
| CONE_0030 protein network | https://string-db.org/network/1208920.CONE_0030 | M23-like peptidase; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.56; Protein involved in hydrolase activity and proteolysis. |
| erpA protein network | https://string-db.org/network/1208920.CONE_0031 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters. |
| argC protein network | https://string-db.org/network/1208920.CONE_0032 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydroge [...] |
| rpsI protein network | https://string-db.org/network/1208920.CONE_0034 | Small subunit ribosomal protein S9; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.34; Protein involved in translation; Belongs to the universal ribosomal protein uS9 f [...] |
| rplM protein network | https://string-db.org/network/1208920.CONE_0035 | Large subunit ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the ea [...] |
| CONE_0036 protein network | https://string-db.org/network/1208920.CONE_0036 | PmbA protein; General function prediction only; SecretomeP prediction: 0.18. |
| CONE_0037 protein network | https://string-db.org/network/1208920.CONE_0037 | Phospholipase/carboxylesterase; General function prediction only; SecretomeP prediction: 0.22; Protein involved in hydrolase activity. |
| CONE_0038 protein network | https://string-db.org/network/1208920.CONE_0038 | Acetyltransferase; Energy production and conversion; SecretomeP prediction: 0.18; Protein involved in transferase activity and metabolic process. |
| gltX protein network | https://string-db.org/network/1208920.CONE_0039 | glutamyl-tRNA synthetase gltX; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor [...] |
| CONE_0040 protein network | https://string-db.org/network/1208920.CONE_0040 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. |
| CONE_0041 protein network | https://string-db.org/network/1208920.CONE_0041 | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Be [...] |
| prmA protein network | https://string-db.org/network/1208920.CONE_0042 | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. |
| CONE_0043 protein network | https://string-db.org/network/1208920.CONE_0043 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier [...] |
| CONE_0044 protein network | https://string-db.org/network/1208920.CONE_0044 | acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carr [...] |
| aroQ protein network | https://string-db.org/network/1208920.CONE_0045 | 3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. |
| CONE_0047 protein network | https://string-db.org/network/1208920.CONE_0047 | Exoribonuclease II; Transcription; SecretomeP prediction: 0.14; Protein involved in ribonuclease activity and hydrolase activity. |
| aroE protein network | https://string-db.org/network/1208920.CONE_0048 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshiki [...] |
| CONE_0052 protein network | https://string-db.org/network/1208920.CONE_0052 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); SecretomeP prediction: 0.05; Protein involved in hydrolase activity. |
| CONE_0053 protein network | https://string-db.org/network/1208920.CONE_0053 | Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. |
| CONE_0054 protein network | https://string-db.org/network/1208920.CONE_0054 | Transcriptional regulator; Transcription; SecretomeP prediction: 0.05; Protein involved in kinase activity; Belongs to the UPF0301 (AlgH) family. |
| hemL protein network | https://string-db.org/network/1208920.CONE_0055 | Glutamate-1-semialdehyde 2,1-aminomutase GSA; Coenzyme metabolism; SecretomeP prediction: 0.16; Protein involved in glutamate-1-semialdehyde 2,1-aminomutase activity. |
| panC protein network | https://string-db.org/network/1208920.CONE_0056 | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase f [...] |
| CONE_0057 protein network | https://string-db.org/network/1208920.CONE_0057 | Conserved hypothetical protein of the DUF3460 family; SecretomeP prediction: 0.78. |
| CONE_0058 protein network | https://string-db.org/network/1208920.CONE_0058 | Octaprenyl diphosphate synthase; Coenzyme metabolism; SecretomeP prediction: 0.06; Protein involved in transferase activity; Belongs to the FPP/GGPP synthase family. |
| rplU protein network | https://string-db.org/network/1208920.CONE_0059 | Large subunit ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. |
| rpmA protein network | https://string-db.org/network/1208920.CONE_0060 | Large subunit ribosomal protein L27; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.53; Belongs to the bacterial ribosomal protein bL27 family. |
| obg protein network | https://string-db.org/network/1208920.CONE_0062 | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role [...] |
| CONE_0064 protein network | https://string-db.org/network/1208920.CONE_0064 | Carboxyl-terminal processing protease; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.09; Protein involved in hydrolase activity; Belongs to the peptidase S41A family. |
| gpmA protein network | https://string-db.org/network/1208920.CONE_0065 | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. |
| CONE_0066 protein network | https://string-db.org/network/1208920.CONE_0066 | Sulfurtransferase; Inorganic ion transport and metabolism; SecretomeP prediction: 0.45. |
| CONE_0067 protein network | https://string-db.org/network/1208920.CONE_0067 | Preprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor p [...] |
| gpsA protein network | https://string-db.org/network/1208920.CONE_0068 | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Energy production and conversion; SecretomeP prediction: 0.13; Protein involved in oxidation-reduction process; Belongs to the NAD-dependent glycerol [...] |
| trmL protein network | https://string-db.org/network/1208920.CONE_0069 | TrmH family, group 2 RNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methy [...] |
| CONE_0070 protein network | https://string-db.org/network/1208920.CONE_0070 | Biotin synthesis protein BioC; Coenzyme metabolism; SecretomeP prediction: 0.21; Protein involved in methyltransferase activity and transferase activity. |
| CONE_0071 protein network | https://string-db.org/network/1208920.CONE_0071 | Two-component system response regulator; Signal transduction mechanisms; SecretomeP prediction: 0.09; Protein involved in regulation of transcription, DNA-dependent. |
| CONE_0072 protein network | https://string-db.org/network/1208920.CONE_0072 | Ribosomal RNA small subunit methyltransferase B; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.19; Protein involved in transferase activity; Belongs to the class I-lik [...] |
| fmt protein network | https://string-db.org/network/1208920.CONE_0073 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...] |
| def protein network | https://string-db.org/network/1208920.CONE_0074 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...] |
| CONE_0075 protein network | https://string-db.org/network/1208920.CONE_0075 | Type III pyridoxal 5-phosphate-dependent enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC [...] |
| ilvA protein network | https://string-db.org/network/1208920.CONE_0076 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a producti [...] |
| CONE_0077 protein network | https://string-db.org/network/1208920.CONE_0077 | Thiol reductant ABC exporter, CydC subunit; Energy production and conversion / Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.3; Protein involved in transm [...] |
| CONE_0078 protein network | https://string-db.org/network/1208920.CONE_0078 | Thiol reductant ABC exporter, CydD subunit; Energy production and conversion / Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.21; Protein involved in trans [...] |
| CONE_0079 protein network | https://string-db.org/network/1208920.CONE_0079 | Cytochrome bd-I oxidase subunit II; Energy production and conversion; SecretomeP prediction: 0.36; Protein involved in oxidation-reduction process. |
| CONE_0080 protein network | https://string-db.org/network/1208920.CONE_0080 | Cytochrome bd-I oxidase subunit I; Energy production and conversion; SecretomeP prediction: 0.24; Protein involved in oxidation-reduction process. |
| CONE_0081 protein network | https://string-db.org/network/1208920.CONE_0081 | Putative sigma-54 modulation protein; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.32; Protein involved in primary metabolic process. |
| hprK protein network | https://string-db.org/network/1208920.CONE_0082 | HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-depend [...] |
| rsmI protein network | https://string-db.org/network/1208920.CONE_0084 | S-adenosylmethionine-dependent methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. |
| CONE_0086 protein network | https://string-db.org/network/1208920.CONE_0086 | Periplasmic or secreted lipoprotein; General function prediction only; SecretomeP prediction: 0.21. |
| argB protein network | https://string-db.org/network/1208920.CONE_0088 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. |
| CONE_0089 protein network | https://string-db.org/network/1208920.CONE_0089 | Sodium:sulfate symporter, transmembrane region; Inorganic ion transport and metabolism; SecretomeP prediction: 0.17; Protein involved in transmembrane transport. |
| CONE_0090 protein network | https://string-db.org/network/1208920.CONE_0090 | L-lactate dehydrogenase; Energy production and conversion; SecretomeP prediction: 0.78; Protein involved in oxidation-reduction process; Belongs to the LDH2/MDH2 oxidoreductase family. |
| mrdB protein network | https://string-db.org/network/1208920.CONE_0093 | Rod shape determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. |
| CONE_0094 protein network | https://string-db.org/network/1208920.CONE_0094 | Penicillin-binding protein 2; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.06; Protein involved in transferase activity, transferring glycosyl groups and peptidoglycan-based [...] |
| CONE_0095 protein network | https://string-db.org/network/1208920.CONE_0095 | Rod shape-determining protein MreD; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.37. |
| CONE_0096 protein network | https://string-db.org/network/1208920.CONE_0096 | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. |
| CONE_0097 protein network | https://string-db.org/network/1208920.CONE_0097 | Rod shape-determining protein MreB; Cell division and chromosome partitioning; SecretomeP prediction: 0.05; Protein involved in ATP binding. |
| CONE_0098 protein network | https://string-db.org/network/1208920.CONE_0098 | aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) [...] |
| gatA protein network | https://string-db.org/network/1208920.CONE_0100 | aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms whi [...] |
| gatB protein network | https://string-db.org/network/1208920.CONE_0101 | aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) [...] |
| pyrE protein network | https://string-db.org/network/1208920.CONE_0102 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). |
| CONE_0103 protein network | https://string-db.org/network/1208920.CONE_0103 | Exodeoxyribonuclease III; DNA replication, recombination, and repair; SecretomeP prediction: 0.04; Protein involved in hydrolase activity and DNA repair. |
| CONE_0104 protein network | https://string-db.org/network/1208920.CONE_0104 | Lysine efflux permease; General function prediction only; SecretomeP prediction: 0.33. |
| ung protein network | https://string-db.org/network/1208920.CONE_0105 | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. |
| CONE_0107 protein network | https://string-db.org/network/1208920.CONE_0107 | Superfamily II DNA and RNA helicase; DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.66; Protein involved in [...] |
| CONE_0109 protein network | https://string-db.org/network/1208920.CONE_0109 | Hypothetical protein; Function unknown; SecretomeP prediction: 0.12. |
| CONE_0110 protein network | https://string-db.org/network/1208920.CONE_0110 | CCA-adding enzyme tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleo [...] |
| CONE_0111 protein network | https://string-db.org/network/1208920.CONE_0111 | 5,10-methenyltetrahydrofolate synthetase; Coenzyme metabolism; SecretomeP prediction: 0.09; Protein involved in 5-formyltetrahydrofolate cyclo-ligase activity. |
| CONE_0112 protein network | https://string-db.org/network/1208920.CONE_0112 | Protein of unknown function DUF1289; General function prediction only; SecretomeP prediction: 0.17. |
| metK protein network | https://string-db.org/network/1208920.CONE_0113 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet forma [...] |
| CONE_0115 protein network | https://string-db.org/network/1208920.CONE_0115 | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid iva acyltransferase msbB; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.09; Protein involved in transferase activity. |
| dapF protein network | https://string-db.org/network/1208920.CONE_0116 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...] |
| xerC protein network | https://string-db.org/network/1208920.CONE_0117 | Integrase/recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert [...] |
| CONE_0118 protein network | https://string-db.org/network/1208920.CONE_0118 | Cobalamin synthesis protein; General function prediction only; SecretomeP prediction: 0.09. |
| dksA protein network | https://string-db.org/network/1208920.CONE_0119 | DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several am [...] |
| hslV protein network | https://string-db.org/network/1208920.CONE_0120 | ATP-dependent HslUV protease, peptidase subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. |
| hslU protein network | https://string-db.org/network/1208920.CONE_0121 | ATP-dependent HslUV protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolys [...] |
| CONE_0122 protein network | https://string-db.org/network/1208920.CONE_0122 | Protein of unknown function of the DUF493 family; Function unknown; SecretomeP prediction: 0.06; Belongs to the UPF0250 family. |
| CONE_0123 protein network | https://string-db.org/network/1208920.CONE_0123 | Penicillin-binding D-alanyl-D-alanine carboxypeptidase; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.09; Protein involved in hydrolase activity; Belongs to the peptidase S11 [...] |
| CONE_0125 protein network | https://string-db.org/network/1208920.CONE_0125 | Hydrolase of the alpha/beta superfamily; General function prediction only; SecretomeP prediction: 0.1; Protein involved in hydrolase activity. |
| CONE_0126 protein network | https://string-db.org/network/1208920.CONE_0126 | BirA family transcriptional regulator, biotin operon repressor; Coenzyme metabolism; SecretomeP prediction: 0.06; Protein involved in ligase activity. |
| coaX protein network | https://string-db.org/network/1208920.CONE_0127 | Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. |
| aspS protein network | https://string-db.org/network/1208920.CONE_0128 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: [...] |
| CONE_0129 protein network | https://string-db.org/network/1208920.CONE_0129 | Conserved hypothetical membrane protein; Function unknown; SecretomeP prediction: 0.14. |
| CONE_0130 protein network | https://string-db.org/network/1208920.CONE_0130 | Aspartate aminotransferase; Transcription / Amino acid transport and metabolism; SecretomeP prediction: 0.25; Protein involved in pyridoxal phosphate binding. |
| ubiA protein network | https://string-db.org/network/1208920.CONE_0132 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubi [...] |
| panB protein network | https://string-db.org/network/1208920.CONE_0133 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to [...] |
| CONE_0134 protein network | https://string-db.org/network/1208920.CONE_0134 | Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of actio [...] |
| CONE_0135 protein network | https://string-db.org/network/1208920.CONE_0135 | Excinuclease ABC subunit A uvrA; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex compos [...] |
| aroB protein network | https://string-db.org/network/1208920.CONE_0136 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). |
| aroK protein network | https://string-db.org/network/1208920.CONE_0137 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. |
| CONE_0140 protein network | https://string-db.org/network/1208920.CONE_0140 | Penicillin-binding protein 1A; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.17; Protein involved in response to antibiotic. |
| cyaY protein network | https://string-db.org/network/1208920.CONE_0141 | CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. |
| CONE_0142 protein network | https://string-db.org/network/1208920.CONE_0142 | Hypothetical protein. |
| lysA protein network | https://string-db.org/network/1208920.CONE_0143 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. |
| engB protein network | https://string-db.org/network/1208920.CONE_0145 | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase fam [...] |
| CONE_0146 protein network | https://string-db.org/network/1208920.CONE_0146 | Porphobilinogen synthase AlaD; Coenzyme metabolism; SecretomeP prediction: 0.15; Protein involved in metal ion binding; Belongs to the ALAD family. |
| rplQ protein network | https://string-db.org/network/1208920.CONE_0148 | Large subunit ribosomal protein L17; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.39. |
| rpoA protein network | https://string-db.org/network/1208920.CONE_0149 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. |
| rpsD protein network | https://string-db.org/network/1208920.CONE_0150 | Small subunit ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. |
| rpsK protein network | https://string-db.org/network/1208920.CONE_0151 | Small subunit ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribos [...] |
| rpsM protein network | https://string-db.org/network/1208920.CONE_0152 | Small subunit ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and [...] |
| infA protein network | https://string-db.org/network/1208920.CONE_0153 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...] |
| secY protein network | https://string-db.org/network/1208920.CONE_0154 | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at t [...] |
| rplO protein network | https://string-db.org/network/1208920.CONE_0155 | Large subunit ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. |
| rpmD protein network | https://string-db.org/network/1208920.CONE_0156 | Large subunit ribosomal protein L30; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.39. |
| rpsE protein network | https://string-db.org/network/1208920.CONE_0157 | Small subunit ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal prote [...] |
| rplR protein network | https://string-db.org/network/1208920.CONE_0159 | Large subunit ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central [...] |
| rplF protein network | https://string-db.org/network/1208920.CONE_0160 | Large subunit ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and [...] |
| rpsH protein network | https://string-db.org/network/1208920.CONE_0161 | Small subunit ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; B [...] |
| rpsN protein network | https://string-db.org/network/1208920.CONE_0162 | Small subunit ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs [...] |
| rplE protein network | https://string-db.org/network/1208920.CONE_0163 | Large subunit ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central pr [...] |
| rplX protein network | https://string-db.org/network/1208920.CONE_0164 | Large subunit ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. |
| rplN protein network | https://string-db.org/network/1208920.CONE_0165 | Large subunit ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. |
| rpsQ protein network | https://string-db.org/network/1208920.CONE_0166 | Small subunit ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. |
| rpmC protein network | https://string-db.org/network/1208920.CONE_0167 | Large subunit ribosomal protein L29; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.35; Protein involved in translation; Belongs to the universal ribosomal protein uL29 [...] |
| rplP protein network | https://string-db.org/network/1208920.CONE_0168 | Large subunit ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. |
| rpsC protein network | https://string-db.org/network/1208920.CONE_0169 | Small subunit ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 fa [...] |
| rplV protein network | https://string-db.org/network/1208920.CONE_0170 | Large subunit ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lin [...] |
| rpsS protein network | https://string-db.org/network/1208920.CONE_0171 | Small subunit ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. |
| rplB protein network | https://string-db.org/network/1208920.CONE_0172 | Large subunit ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond form [...] |
| rplW protein network | https://string-db.org/network/1208920.CONE_0173 | Large subunit ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the [...] |
| rplD protein network | https://string-db.org/network/1208920.CONE_0174 | Large subunit ribosomal protein L4; Forms part of the polypeptide exit tunnel. |
| rplC protein network | https://string-db.org/network/1208920.CONE_0175 | Large subunit ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. |
| rpsJ protein network | https://string-db.org/network/1208920.CONE_0176 | Small subunit ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. |
| tuf protein network | https://string-db.org/network/1208920.CONE_0178 | Elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. |
| fusA protein network | https://string-db.org/network/1208920.CONE_0181 | Elongation factor EF-G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the po [...] |
| rpsG protein network | https://string-db.org/network/1208920.CONE_0182 | Small subunit ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the su [...] |
| rpsL protein network | https://string-db.org/network/1208920.CONE_0183 | Small subunit ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of [...] |
| rpoC protein network | https://string-db.org/network/1208920.CONE_0184 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. |
| rpoB protein network | https://string-db.org/network/1208920.CONE_0185 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. |
| rplL protein network | https://string-db.org/network/1208920.CONE_0186 | Large subunit ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs [...] |
| rplJ protein network | https://string-db.org/network/1208920.CONE_0188 | Large subunit ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribo [...] |
| rplA protein network | https://string-db.org/network/1208920.CONE_0189 | Large subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. |
| rplK protein network | https://string-db.org/network/1208920.CONE_0190 | Large subunit ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. |
| nusG protein network | https://string-db.org/network/1208920.CONE_0191 | Transcriptional antiterminator NusG; Participates in transcription elongation, termination and antitermination. |
| CONE_0192 protein network | https://string-db.org/network/1208920.CONE_0192 | Preprotein translocase subunit SecE; Intracellular trafficking and secretion; SecretomeP prediction: 0.15; Belongs to the SecE/SEC61-gamma family. |
| rsmG protein network | https://string-db.org/network/1208920.CONE_0193 | Glucose inhibited division protein B; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. |
| mnmG protein network | https://string-db.org/network/1208920.CONE_0194 | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s( [...] |
| CONE_0195 protein network | https://string-db.org/network/1208920.CONE_0195 | Elongation factor EF-Tu; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.05; Protein involved in hydrolase activity and translational elongation. |
| mnmE protein network | https://string-db.org/network/1208920.CONE_0196 | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, [...] |
| yidC protein network | https://string-db.org/network/1208920.CONE_0197 | Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane [...] |
| CONE_0198 protein network | https://string-db.org/network/1208920.CONE_0198 | Conserved hypothetical protein of the DUF37 family; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. |
| rnpA protein network | https://string-db.org/network/1208920.CONE_0199 | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...] |
| rpmH protein network | https://string-db.org/network/1208920.CONE_0201 | Large subunit ribosomal protein L34; SecretomeP prediction: 0.58; Belongs to the bacterial ribosomal protein bL34 family. |
| dnaA protein network | https://string-db.org/network/1208920.CONE_0202 | Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically doub [...] |
| CONE_0203 protein network | https://string-db.org/network/1208920.CONE_0203 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadin [...] |
| gyrB protein network | https://string-db.org/network/1208920.CONE_0204 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...] |
| CONE_0205 protein network | https://string-db.org/network/1208920.CONE_0205 | Hypothetical protein; Secondary metabolites biosynthesis, transport, and catabolism; SecretomeP prediction: 0.09; Protein involved in metabolic process. |
| CONE_0207 protein network | https://string-db.org/network/1208920.CONE_0207 | DNA topoisomerase III; DNA replication, recombination, and repair; SecretomeP prediction: 0.15; Protein involved in isomerase activity. |
| CONE_0208 protein network | https://string-db.org/network/1208920.CONE_0208 | acetylornithine/N-succinyldiaminopimelate aminotransferase; Amino acid transport and metabolism; SecretomeP prediction: 0.07; Protein involved in pyridoxal phosphate binding; Belongs to the class [...] |
| CONE_0209 protein network | https://string-db.org/network/1208920.CONE_0209 | Thiol:disulfide interchange protein DsbA; Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.21; Protein involved in cell redox homeostasis. |
| argS protein network | https://string-db.org/network/1208920.CONE_0210 | arginyl-tRNA synthetase; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.15; Protein involved in ligase activity. |
| leuA protein network | https://string-db.org/network/1208920.CONE_0211 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isoprop [...] |
| CONE_0213 protein network | https://string-db.org/network/1208920.CONE_0213 | Hypothetical protein; SecretomeP prediction: 0.24. |
| prfC protein network | https://string-db.org/network/1208920.CONE_0214 | Peptide chain release factor RF-3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference fo [...] |
| CONE_0215 protein network | https://string-db.org/network/1208920.CONE_0215 | Stringent starvation protein B; General function prediction only; SecretomeP prediction: 0.83. |
| CONE_0216 protein network | https://string-db.org/network/1208920.CONE_0216 | Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.06; Protein involved in transferase activity; Belongs to the GST superfamily. |
| CONE_0217 protein network | https://string-db.org/network/1208920.CONE_0217 | NIF3 family metal-binding protein; Function unknown; SecretomeP prediction: 0.29. |
| CONE_0218 protein network | https://string-db.org/network/1208920.CONE_0218 | Cell-cycle regulation hit-like protein; Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only; SecretomeP prediction: 0.08; Protein involv [...] |
| hisE protein network | https://string-db.org/network/1208920.CONE_0220 | phosphoribosyl-ATP pyrophosphohydrolase; Amino acid transport and metabolism; SecretomeP prediction: 0.09; Protein involved in hydrolase activity. |
| hisI protein network | https://string-db.org/network/1208920.CONE_0221 | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. |
| hisF protein network | https://string-db.org/network/1208920.CONE_0222 | Cyclase HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using th [...] |
| hisA protein network | https://string-db.org/network/1208920.CONE_0223 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide isomerase HisA; Amino acid transport and metabolism; SecretomeP prediction: 0.04; Protein involved in isomerase activity. |
| hisH protein network | https://string-db.org/network/1208920.CONE_0224 | Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as pa [...] |
| hisB protein network | https://string-db.org/network/1208920.CONE_0225 | Imidazoleglycerol-phosphate dehydratase; Amino acid transport and metabolism; SecretomeP prediction: 0.05; Protein involved in lyase activity. |
| hisC protein network | https://string-db.org/network/1208920.CONE_0226 | Histidinol-phosphate aminotransferase; Amino acid transport and metabolism; SecretomeP prediction: 0.07; Protein involved in pyridoxal phosphate binding; Belongs to the class-II pyridoxal-phospha [...] |
| hisD protein network | https://string-db.org/network/1208920.CONE_0227 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. |
| hisG protein network | https://string-db.org/network/1208920.CONE_0228 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...] |
| murA protein network | https://string-db.org/network/1208920.CONE_0231 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. |
| CONE_0233 protein network | https://string-db.org/network/1208920.CONE_0233 | ABC-2 type transport system permease protein; Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.35; Protein involved in ATPase activity, c [...] |
| CONE_0234 protein network | https://string-db.org/network/1208920.CONE_0234 | ABC-2 type transport system ATP-binding protein; Defense mechanisms; SecretomeP prediction: 0.09; Protein involved in nucleoside-triphosphatase activity. |
| CONE_0235 protein network | https://string-db.org/network/1208920.CONE_0235 | Toluene tolerance protein; Secondary metabolites biosynthesis, transport, and catabolism; SecretomeP prediction: 0.26. |
| CONE_0236 protein network | https://string-db.org/network/1208920.CONE_0236 | Lipoprotein; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.27. |
| CONE_0238 protein network | https://string-db.org/network/1208920.CONE_0238 | ABC transport system substrate-binding protein; Secondary metabolites biosynthesis, transport, and catabolism; SecretomeP prediction: 0.29. |
| CONE_0239 protein network | https://string-db.org/network/1208920.CONE_0239 | ABC transport system permease protein; Secondary metabolites biosynthesis, transport, and catabolism; SecretomeP prediction: 0.08. |
| CONE_0240 protein network | https://string-db.org/network/1208920.CONE_0240 | ABC transport system ATP-binding protein; Secondary metabolites biosynthesis, transport, and catabolism; SecretomeP prediction: 0.08; Protein involved in nucleoside-triphosphatase activity. |
| CONE_0241 protein network | https://string-db.org/network/1208920.CONE_0241 | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. |
| CONE_0243 protein network | https://string-db.org/network/1208920.CONE_0243 | CPA1 family monovalent cation:H+ antiporter; Inorganic ion transport and metabolism; SecretomeP prediction: 0.14; Protein involved in transmembrane transport. |
| glmU protein network | https://string-db.org/network/1208920.CONE_0246 | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer [...] |
| glmS protein network | https://string-db.org/network/1208920.CONE_0248 | Isomerizing glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. |
| trpC protein network | https://string-db.org/network/1208920.CONE_0249 | Indole-3-glycerol phosphate synthase; Amino acid transport and metabolism; SecretomeP prediction: 0.12; Protein involved in lyase activity and carboxy-lyase activity; Belongs to the TrpC family. |
| trpD protein network | https://string-db.org/network/1208920.CONE_0250 | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranila [...] |
| CONE_0251 protein network | https://string-db.org/network/1208920.CONE_0251 | Anthranilate synthase component II; Amino acid transport and metabolism / Coenzyme metabolism; SecretomeP prediction: 0.05; Protein involved in lyase activity. |
| CONE_0252 protein network | https://string-db.org/network/1208920.CONE_0252 | Anthranilate synthase component I; Amino acid transport and metabolism / Coenzyme metabolism; SecretomeP prediction: 0.07; Protein involved in oxo-acid-lyase activity. |
| CONE_0253 protein network | https://string-db.org/network/1208920.CONE_0253 | Ribulose-phosphate 3-epimerase; Carbohydrate transport and metabolism; SecretomeP prediction: 0.21; Protein involved in isomerase activity; Belongs to the ribulose-phosphate 3-epimerase family. |
| CONE_0255 protein network | https://string-db.org/network/1208920.CONE_0255 | Ubiquinone biosynthesis hydroxylase; Coenzyme metabolism / Energy production and conversion; SecretomeP prediction: 0.07; Protein involved in oxidation-reduction process. |
| CONE_0256 protein network | https://string-db.org/network/1208920.CONE_0256 | Dihydroneopterin aldolase; Coenzyme metabolism; SecretomeP prediction: 0.19; Protein involved in lyase activity. |
| CONE_0257 protein network | https://string-db.org/network/1208920.CONE_0257 | Hypothetical protein; SecretomeP prediction: 0.45. |
| atpB protein network | https://string-db.org/network/1208920.CONE_0258 | F-type H+-transporting ATPase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. |
| atpE protein network | https://string-db.org/network/1208920.CONE_0259 | F-type H+-transporting ATPase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) contain [...] |
| CONE_0261 protein network | https://string-db.org/network/1208920.CONE_0261 | F-type H+-transporting ATPase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). Belongs to the ATPase B chain family. |
| atpH protein network | https://string-db.org/network/1208920.CONE_0262 | F-type H+-transporting ATPase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) con [...] |
| atpA protein network | https://string-db.org/network/1208920.CONE_0263 | F-type H+-transporting ATPase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. |
| atpG protein network | https://string-db.org/network/1208920.CONE_0264 | F-type H+-transporting ATPase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activ [...] |
| atpD protein network | https://string-db.org/network/1208920.CONE_0265 | F-type H+-transporting ATPase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. |
| atpC protein network | https://string-db.org/network/1208920.CONE_0266 | F-type H+-transporting ATPase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. |
| hemE protein network | https://string-db.org/network/1208920.CONE_0267 | Uroporphyrinogen decarboxylase uroD; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. |
| priA protein network | https://string-db.org/network/1208920.CONE_0268 | Superfamily II primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA du [...] |
| nnrD protein network | https://string-db.org/network/1208920.CONE_0269 | Carbohydrate kinase family protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epi [...] |
| gshA protein network | https://string-db.org/network/1208920.CONE_0270 | Glutamate--cysteine ligase; Coenzyme metabolism; SecretomeP prediction: 0.33; Protein involved in ligase activity; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. |
| ubiE protein network | https://string-db.org/network/1208920.CONE_0271 | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methox [...] |
| CONE_0274 protein network | https://string-db.org/network/1208920.CONE_0274 | Tim44-like domain containing protein; Function unknown; SecretomeP prediction: 0.07; Protein involved in P-P-bond-hydrolysis-driven protein transmembrane transporter activity. |
| CONE_0275 protein network | https://string-db.org/network/1208920.CONE_0275 | Hypothetical protein; SecretomeP prediction: 0.25. |
| CONE_0276 protein network | https://string-db.org/network/1208920.CONE_0276 | Ubiquinone biosynthesis protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfam [...] |
| coaE protein network | https://string-db.org/network/1208920.CONE_0277 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. |
| zapD protein network | https://string-db.org/network/1208920.CONE_0278 | Conserved hypothetical protein of the DUF1342 family; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a redu [...] |
| CONE_0279 protein network | https://string-db.org/network/1208920.CONE_0279 | Putative ATPase of the DUF815 family; General function prediction only; SecretomeP prediction: 0.1; Protein involved in nucleoside-triphosphatase activity. |
| argJ protein network | https://string-db.org/network/1208920.CONE_0281 | Glutamate N-acetyltransferase/amino-acid N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from g [...] |
| hemA protein network | https://string-db.org/network/1208920.CONE_0283 | glutamyl-tRNA reductase hemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). |
| prfA protein network | https://string-db.org/network/1208920.CONE_0284 | Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. |
| prmC protein network | https://string-db.org/network/1208920.CONE_0285 | Methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5- [...] |
| CONE_0286 protein network | https://string-db.org/network/1208920.CONE_0286 | Monothiol glutaredoxin; Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.06; Protein involved in cell redox homeostasis; Belongs to the glutaredoxin family. [...] |
| ubiX protein network | https://string-db.org/network/1208920.CONE_0287 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarbo [...] |
| CONE_0288 protein network | https://string-db.org/network/1208920.CONE_0288 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. |
| ppc protein network | https://string-db.org/network/1208920.CONE_0289 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. |
| queC protein network | https://string-db.org/network/1208920.CONE_0290 | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. |
| ilvD protein network | https://string-db.org/network/1208920.CONE_0291 | Dihydroxy-acid dehydratase; Amino acid transport and metabolism / Carbohydrate transport and metabolism; SecretomeP prediction: 0.08; Protein involved in lyase activity; Belongs to the IlvD/Edd f [...] |
| CONE_0292 protein network | https://string-db.org/network/1208920.CONE_0292 | Permease protein; General function prediction only; SecretomeP prediction: 0.39. |
| htpG protein network | https://string-db.org/network/1208920.CONE_0293 | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. |
| ffh protein network | https://string-db.org/network/1208920.CONE_0295 | Signal recognition particle subunit SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome [...] |
| CONE_0296 protein network | https://string-db.org/network/1208920.CONE_0296 | Threonine dehydratase; Amino acid transport and metabolism; SecretomeP prediction: 0.07; Protein involved in pyridoxal phosphate binding. |
| metG protein network | https://string-db.org/network/1208920.CONE_0298 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. |
| CONE_0299 protein network | https://string-db.org/network/1208920.CONE_0299 | Chromosome partitioning ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. |
| CONE_0300 protein network | https://string-db.org/network/1208920.CONE_0300 | Surface antigen family protein; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.17. |
| CONE_0301 protein network | https://string-db.org/network/1208920.CONE_0301 | Hypothetical protein with a DUF490 domain; Function unknown; SecretomeP prediction: 0.05. |
| dcd protein network | https://string-db.org/network/1208920.CONE_0302 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. |
| CONE_0303 protein network | https://string-db.org/network/1208920.CONE_0303 | Arginine decarboxylase; Amino acid transport and metabolism; SecretomeP prediction: 0.08; Protein involved in pyridoxal phosphate binding. |
| CONE_0304 protein network | https://string-db.org/network/1208920.CONE_0304 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. |
| thyA protein network | https://string-db.org/network/1208920.CONE_0305 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...] |
| coq7 protein network | https://string-db.org/network/1208920.CONE_0306 | Ubiquinone biosynthesis monooxygenase Coq7; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. |
| CONE_0307 protein network | https://string-db.org/network/1208920.CONE_0307 | Glycolate oxidase, subunit GlcD; Energy production and conversion; SecretomeP prediction: 0.26; Protein involved in flavin adenine dinucleotide binding. |
| mutM protein network | https://string-db.org/network/1208920.CONE_0308 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a [...] |
| CONE_0310 protein network | https://string-db.org/network/1208920.CONE_0310 | Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. |
| ispE protein network | https://string-db.org/network/1208920.CONE_0311 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. |
| prs protein network | https://string-db.org/network/1208920.CONE_0312 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...] |
| rplY protein network | https://string-db.org/network/1208920.CONE_0313 | Large subunit ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal prote [...] |
| pth protein network | https://string-db.org/network/1208920.CONE_0314 | PTH1 family peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. |
| CONE_0315 protein network | https://string-db.org/network/1208920.CONE_0315 | Hypothetical protein; SecretomeP prediction: 0.31. |
| ychF protein network | https://string-db.org/network/1208920.CONE_0316 | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. |
| coaD protein network | https://string-db.org/network/1208920.CONE_0317 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial Co [...] |
| groL protein network | https://string-db.org/network/1208920.CONE_0318 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. |
| groS protein network | https://string-db.org/network/1208920.CONE_0320 | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. |
| lptD protein network | https://string-db.org/network/1208920.CONE_0322 | LPS-assembly protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. |
| surA protein network | https://string-db.org/network/1208920.CONE_0323 | Peptidyl-prolyl cis-trans isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation [...] |
| rsmA protein network | https://string-db.org/network/1208920.CONE_0324 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...] |
| CONE_0325 protein network | https://string-db.org/network/1208920.CONE_0325 | Magnesium transporter; Acts as a magnesium transporter. |
| CONE_0326 protein network | https://string-db.org/network/1208920.CONE_0326 | acyl-CoA thioesterase YciA; Lipid metabolism; SecretomeP prediction: 0.25. |
| CONE_0327 protein network | https://string-db.org/network/1208920.CONE_0327 | Myo-inositol-1(or 4)-monophosphatase; Carbohydrate transport and metabolism; SecretomeP prediction: 0.05; Protein involved in inositol monophosphate 1-phosphatase activity and hydrolase activity; [...] |
| CONE_0328 protein network | https://string-db.org/network/1208920.CONE_0328 | Hypothetical protein; Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only; SecretomeP prediction: 0.35. |
| CONE_0331 protein network | https://string-db.org/network/1208920.CONE_0331 | Magnesium and cobalt transporter; Inorganic ion transport and metabolism; SecretomeP prediction: 0.05. |
| ybeY protein network | https://string-db.org/network/1208920.CONE_0332 | Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. |
| CONE_0333 protein network | https://string-db.org/network/1208920.CONE_0333 | PhoH-like phosphate starvation-inducible protein; Signal transduction mechanisms; SecretomeP prediction: 0.05; Protein involved in ATP binding. |
| miaB protein network | https://string-db.org/network/1208920.CONE_0334 | Bifunctional tRNA thiolation and methylation protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine [...] |
| secF protein network | https://string-db.org/network/1208920.CONE_0336 | Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete pro [...] |
| secD protein network | https://string-db.org/network/1208920.CONE_0337 | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete pro [...] |
| yajC protein network | https://string-db.org/network/1208920.CONE_0338 | Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into memb [...] |
| tgt protein network | https://string-db.org/network/1208920.CONE_0339 | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in [...] |
| queA protein network | https://string-db.org/network/1208920.CONE_0340 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ [...] |
| CONE_0341 protein network | https://string-db.org/network/1208920.CONE_0341 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiD; Coenzyme metabolism; SecretomeP prediction: 0.09; Protein involved in lyase activity and carboxy-lyase activity; Belongs to the UbiD family. |
| CONE_0342 protein network | https://string-db.org/network/1208920.CONE_0342 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subuni [...] |
| CONE_0343 protein network | https://string-db.org/network/1208920.CONE_0343 | Transketolase; Carbohydrate transport and metabolism; SecretomeP prediction: 0.16; Protein involved in transferase activity; Belongs to the transketolase family. |
| CONE_0344 protein network | https://string-db.org/network/1208920.CONE_0344 | Glyceraldehyde 3-phosphate dehydrogenase; Carbohydrate transport and metabolism; SecretomeP prediction: 0.31; Protein involved in oxidation-reduction process; Belongs to the glyceraldehyde-3-phos [...] |
| pgk protein network | https://string-db.org/network/1208920.CONE_0345 | Phosphoglycerate kinase; Carbohydrate transport and metabolism; SecretomeP prediction: 0.06; Protein involved in transferase activity; Belongs to the phosphoglycerate kinase family. |
| CONE_0347 protein network | https://string-db.org/network/1208920.CONE_0347 | PiT family inorganic phosphate transporter; Inorganic ion transport and metabolism; SecretomeP prediction: 0.35. |
| CONE_0348 protein network | https://string-db.org/network/1208920.CONE_0348 | Class II fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bi [...] |
| purC protein network | https://string-db.org/network/1208920.CONE_0349 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Nucleotide transport and metabolism; SecretomeP prediction: 0.18; Protein involved in ligase activity; Belongs to the SAICAR synthetase f [...] |
| purE protein network | https://string-db.org/network/1208920.CONE_0350 | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). |
| purK protein network | https://string-db.org/network/1208920.CONE_0351 | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAI [...] |
| CONE_0352 protein network | https://string-db.org/network/1208920.CONE_0352 | Putative translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. |
| xerD protein network | https://string-db.org/network/1208920.CONE_0354 | Integrase/recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert [...] |
| CONE_0355 protein network | https://string-db.org/network/1208920.CONE_0355 | Hypothetical protein; DNA replication, recombination, and repair; SecretomeP prediction: 0.2. |
| CONE_0356 protein network | https://string-db.org/network/1208920.CONE_0356 | UvrD/Rep helicase family protein. |
| dnaX protein network | https://string-db.org/network/1208920.CONE_0358 | DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' [...] |
| CONE_0359 protein network | https://string-db.org/network/1208920.CONE_0359 | YbaB/EbfC family DNA-binding protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. |
| recR protein network | https://string-db.org/network/1208920.CONE_0361 | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. |
| tal protein network | https://string-db.org/network/1208920.CONE_0362 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. |
| carA protein network | https://string-db.org/network/1208920.CONE_0363 | Carbamoyl-phosphate synthase small subunit; Amino acid transport and metabolism / Nucleotide transport and metabolism; SecretomeP prediction: 0.19; Protein involved in ligase activity; Belongs to [...] |
| carB protein network | https://string-db.org/network/1208920.CONE_0364 | Carbamoyl-phosphate synthase large subunit; Amino acid transport and metabolism / Nucleotide transport and metabolism; SecretomeP prediction: 0.07; Protein involved in metal ion binding; Belongs [...] |
| greA protein network | https://string-db.org/network/1208920.CONE_0365 | Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...] |
| CONE_0366 protein network | https://string-db.org/network/1208920.CONE_0366 | YhbY family RNA-binding protein; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.04. |
| rlmE protein network | https://string-db.org/network/1208920.CONE_0367 | Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. |
| ftsH protein network | https://string-db.org/network/1208920.CONE_0368 | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane protein [...] |
| CONE_0369 protein network | https://string-db.org/network/1208920.CONE_0369 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate [...] |
| glmM protein network | https://string-db.org/network/1208920.CONE_0370 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. |
| dapA protein network | https://string-db.org/network/1208920.CONE_0371 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). |
| mutS protein network | https://string-db.org/network/1208920.CONE_0372 | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase act [...] |
| CONE_0373 protein network | https://string-db.org/network/1208920.CONE_0373 | Mechanosensitive channel MscS; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.14; Protein involved in transmembrane transport. |
| CONE_0374 protein network | https://string-db.org/network/1208920.CONE_0374 | Myo-inositol-1(or 4)-monophosphatase; Carbohydrate transport and metabolism; SecretomeP prediction: 0.06; Protein involved in hydrolase activity; Belongs to the inositol monophosphatase superfami [...] |
| CONE_0375 protein network | https://string-db.org/network/1208920.CONE_0375 | TerC family/CBS/transporter; Inorganic ion transport and metabolism; SecretomeP prediction: 0.21. |
| uppP protein network | https://string-db.org/network/1208920.CONE_0376 | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. |
| CONE_0379 protein network | https://string-db.org/network/1208920.CONE_0379 | Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclop [...] |
| cysS protein network | https://string-db.org/network/1208920.CONE_0380 | cysteinyl-tRNA synthetase; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.14; Protein involved in ligase activity; Belongs to the class-I aminoacyl-tRNA synthetase fami [...] |
| CONE_0381 protein network | https://string-db.org/network/1208920.CONE_0381 | DNA-3-methyladenine glycosylase II; DNA replication, recombination, and repair; SecretomeP prediction: 0.05; Protein involved in hydrolase activity, acting on glycosyl bonds and base-excision rep [...] |
| accA protein network | https://string-db.org/network/1208920.CONE_0382 | acetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its car [...] |
| tilS protein network | https://string-db.org/network/1208920.CONE_0383 | tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is c [...] |
| CONE_0384 protein network | https://string-db.org/network/1208920.CONE_0384 | Aspartate kinase; Amino acid transport and metabolism; SecretomeP prediction: 0.09; Protein involved in transferase activity; Belongs to the aspartokinase family. |
| CONE_0385 protein network | https://string-db.org/network/1208920.CONE_0385 | Hypothetical protein of the DUF1178 family; Function unknown; SecretomeP prediction: 0.46. |
| efp protein network | https://string-db.org/network/1208920.CONE_0386 | Elongation factor EF-P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indir [...] |
| CONE_0387 protein network | https://string-db.org/network/1208920.CONE_0387 | EF-P-adjacent protein; Function unknown; SecretomeP prediction: 0.2. |
| CONE_0388 protein network | https://string-db.org/network/1208920.CONE_0388 | DNA polymerase III subunit delta; DNA replication, recombination, and repair; SecretomeP prediction: 0.3; Protein involved in nucleotidyltransferase activity. |
| leuS protein network | https://string-db.org/network/1208920.CONE_0389 | leucyl-tRNA synthetase; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.08; Protein involved in ligase activity; Belongs to the class-I aminoacyl-tRNA synthetase family. |
| rpmG protein network | https://string-db.org/network/1208920.CONE_0390 | Large subunit ribosomal protein L33; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.86; Belongs to the bacterial ribosomal protein bL33 family. |
| rpmB protein network | https://string-db.org/network/1208920.CONE_0392 | Large subunit ribosomal protein L28; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.48; Belongs to the bacterial ribosomal protein bL28 family. |
| pdxJ protein network | https://string-db.org/network/1208920.CONE_0394 | Pyridoxine 5-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino [...] |
| acpS protein network | https://string-db.org/network/1208920.CONE_0395 | Holo-[acyl-carrier protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. |
| uvrC protein network | https://string-db.org/network/1208920.CONE_0396 | Excinuclease ABC subunit C uvrC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is resp [...] |
| CONE_0397 protein network | https://string-db.org/network/1208920.CONE_0397 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Lipid metabolism; SecretomeP prediction: 0.38; Protein involved in phosphotransferase activity, for other substituted phosphate [...] |
| CONE_0398 protein network | https://string-db.org/network/1208920.CONE_0398 | Major facilitator superfamily protein; Carbohydrate transport and metabolism; SecretomeP prediction: 0.35; Protein involved in transmembrane transport. |
| CONE_0399 protein network | https://string-db.org/network/1208920.CONE_0399 | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). |
| CONE_0401 protein network | https://string-db.org/network/1208920.CONE_0401 | Lytic murein transglycosylase; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.15; Protein involved in metabolic process. |
| clpB protein network | https://string-db.org/network/1208920.CONE_0402 | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK [...] |
| CONE_0403 protein network | https://string-db.org/network/1208920.CONE_0403 | Phytoene synthase; Lipid metabolism; SecretomeP prediction: 0.28; Protein involved in geranylgeranyl-diphosphate geranylgeranyltransferase activity. |
| radA protein network | https://string-db.org/network/1208920.CONE_0404 | DNA repair protein RadA/Sms; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated str [...] |
| CONE_0406 protein network | https://string-db.org/network/1208920.CONE_0406 | TRAP-type C4-dicarboxylate transport system, periplasmic component; Carbohydrate transport and metabolism; SecretomeP prediction: 0.12. |
| CONE_0408 protein network | https://string-db.org/network/1208920.CONE_0408 | DNA recombination protein RmuC; General function prediction only; SecretomeP prediction: 0.09. |
| rpiA protein network | https://string-db.org/network/1208920.CONE_0409 | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. |
| CONE_0410 protein network | https://string-db.org/network/1208920.CONE_0410 | Fe(2+) trafficking family protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic [...] |
| CONE_0413 protein network | https://string-db.org/network/1208920.CONE_0413 | DNA polymerase III subunit alpha; DNA replication, recombination, and repair; SecretomeP prediction: 0.12; Protein involved in nucleotidyltransferase activity. |
| CONE_0415 protein network | https://string-db.org/network/1208920.CONE_0415 | Ribonuclease G; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.13; Protein involved in hydrolase activity and RNA processing. |
| rlmH protein network | https://string-db.org/network/1208920.CONE_0416 | SPOUT methyltransferase superfamily protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. |
| rsfS protein network | https://string-db.org/network/1208920.CONE_0418 | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S r [...] |
| nadD protein network | https://string-db.org/network/1208920.CONE_0419 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). |
| purD protein network | https://string-db.org/network/1208920.CONE_0420 | Phosphoribosylamine--glycine ligase; Nucleotide transport and metabolism; SecretomeP prediction: 0.09; Protein involved in ligase activity; Belongs to the GARS family. |
| CONE_0421 protein network | https://string-db.org/network/1208920.CONE_0421 | Hypothetical protein of the DUF28 family; Function unknown; SecretomeP prediction: 0.16. |
| CONE_0422 protein network | https://string-db.org/network/1208920.CONE_0422 | Aspartate carbamoyltransferase catalytic subunit; Nucleotide transport and metabolism; SecretomeP prediction: 0.3; Protein involved in carboxyl- or carbamoyltransferase activity; Belongs to the a [...] |
| recA protein network | https://string-db.org/network/1208920.CONE_0423 | Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybrid [...] |
| CONE_0424 protein network | https://string-db.org/network/1208920.CONE_0424 | Regulatory protein; Modulates RecA activity; Belongs to the RecX family. |
| sucC protein network | https://string-db.org/network/1208920.CONE_0425 | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus repr [...] |
| sucD protein network | https://string-db.org/network/1208920.CONE_0426 | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus rep [...] |
| hemC protein network | https://string-db.org/network/1208920.CONE_0427 | Hydroxymethylbilane synthase PBGD; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. |
| CONE_0428 protein network | https://string-db.org/network/1208920.CONE_0428 | uroporphyrinogen-III synthase uroS; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. |
| CONE_0429 protein network | https://string-db.org/network/1208920.CONE_0429 | uroporphyrin-III C-methyltransferase; Coenzyme metabolism; SecretomeP prediction: 0.27; Protein involved in transferase activity. |
| CONE_0431 protein network | https://string-db.org/network/1208920.CONE_0431 | HemY protein; Coenzyme metabolism; SecretomeP prediction: 0.29; Protein involved in binding. |
| ppa protein network | https://string-db.org/network/1208920.CONE_0432 | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. |
| CONE_0433 protein network | https://string-db.org/network/1208920.CONE_0433 | tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines [...] |
| aroC protein network | https://string-db.org/network/1208920.CONE_0434 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...] |
| leuC protein network | https://string-db.org/network/1208920.CONE_0436 | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. |
| leuD protein network | https://string-db.org/network/1208920.CONE_0437 | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to t [...] |
| leuB protein network | https://string-db.org/network/1208920.CONE_0438 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...] |
| asd protein network | https://string-db.org/network/1208920.CONE_0439 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the as [...] |
| truA protein network | https://string-db.org/network/1208920.CONE_0440 | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. |
| trpF protein network | https://string-db.org/network/1208920.CONE_0441 | Phosphoribosylanthranilate isomerase; Amino acid transport and metabolism; SecretomeP prediction: 0.1; Protein involved in isomerase activity; Belongs to the TrpF family. |
| thrS protein network | https://string-db.org/network/1208920.CONE_0442 | threonyl-tRNA synthetase; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.15; Protein involved in tRNA aminoacylation; Belongs to the class-II aminoacyl-tRNA synthetase [...] |
| infC protein network | https://string-db.org/network/1208920.CONE_0443 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...] |
| gshB protein network | https://string-db.org/network/1208920.CONE_0444 | Glutathione synthase; Coenzyme metabolism / Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.04; Protein involved in ligase activity; Belongs to the prokaryotic GSH synth [...] |
| CONE_0445 protein network | https://string-db.org/network/1208920.CONE_0445 | Phosphocarrier protein; Carbohydrate transport and metabolism; SecretomeP prediction: 0.17; Protein involved in transferase activity. |
| CONE_0446 protein network | https://string-db.org/network/1208920.CONE_0446 | dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP [...] |
| CONE_0447 protein network | https://string-db.org/network/1208920.CONE_0447 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoyl [...] |
| lspA protein network | https://string-db.org/network/1208920.CONE_0448 | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. |
| ileS protein network | https://string-db.org/network/1208920.CONE_0449 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...] |
| CONE_0450 protein network | https://string-db.org/network/1208920.CONE_0450 | Riboflavin kinase/FMN adenylyltransferase; Coenzyme metabolism; SecretomeP prediction: 0.08; Protein involved in transferase activity and nucleotidyltransferase activity; Belongs to the ribF fami [...] |
| purN protein network | https://string-db.org/network/1208920.CONE_0451 | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formy [...] |
| CONE_0453 protein network | https://string-db.org/network/1208920.CONE_0453 | DNA helicase II/ATP-dependent DNA helicase PcrA; DNA replication, recombination, and repair; SecretomeP prediction: 0.1; Protein involved in hydrolase activity. |
| CONE_0454 protein network | https://string-db.org/network/1208920.CONE_0454 | Putative adenine-specific DNA-methyltransferase; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.17; Protein involved in methylation; Belongs to the protein N5-glutamine [...] |
| dapE protein network | https://string-db.org/network/1208920.CONE_0455 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in [...] |
| dapD protein network | https://string-db.org/network/1208920.CONE_0456 | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Amino acid transport and metabolism; SecretomeP prediction: 0.14; Protein involved in diaminopimelate biosynthetic process; Belongs [...] |
| CONE_0458 protein network | https://string-db.org/network/1208920.CONE_0458 | acetylornithine/N-succinyldiaminopimelate aminotransferase; Amino acid transport and metabolism; SecretomeP prediction: 0.7; Protein involved in pyridoxal phosphate binding. |
| CONE_0459 protein network | https://string-db.org/network/1208920.CONE_0459 | CspA family beta-ribbon cold shock protein; Transcription; SecretomeP prediction: 0.39; Protein involved in regulation of transcription, DNA-dependent. |
| tig protein network | https://string-db.org/network/1208920.CONE_0460 | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs t [...] |
| clpP protein network | https://string-db.org/network/1208920.CONE_0461 | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradati [...] |
| clpX protein network | https://string-db.org/network/1208920.CONE_0462 | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in th [...] |
| lon protein network | https://string-db.org/network/1208920.CONE_0465 | ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for [...] |
| CONE_0466 protein network | https://string-db.org/network/1208920.CONE_0466 | Aromatic-amino-acid transaminase; Amino acid transport and metabolism; SecretomeP prediction: 0.1; Protein involved in pyridoxal phosphate binding. |
| uvrB protein network | https://string-db.org/network/1208920.CONE_0467 | Excinuclease ABC subunit B uvrB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA fo [...] |
| CONE_0468 protein network | https://string-db.org/network/1208920.CONE_0468 | Protein-tyrosine phosphatase; Signal transduction mechanisms; SecretomeP prediction: 0.09; Protein involved in hydrolase activity and protein dephosphorylation; Belongs to the low molecular weigh [...] |
| CONE_0469 protein network | https://string-db.org/network/1208920.CONE_0469 | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly 7e-38; Transcription; SecretomeP prediction: 0.07; Protein involved in regulation of transcription, DNA-dependent. |
| iscS protein network | https://string-db.org/network/1208920.CONE_0470 | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental [...] |
| CONE_0471 protein network | https://string-db.org/network/1208920.CONE_0471 | Nitrogen fixation protein NifU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off [...] |
| CONE_0472 protein network | https://string-db.org/network/1208920.CONE_0472 | Iron-sulfur cluster assembly protein; Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.05; Protein involved in iron-sulfur cluster binding; Belongs to the He [...] |
| hscB protein network | https://string-db.org/network/1208920.CONE_0473 | Molecular chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family [...] |
| CONE_0474 protein network | https://string-db.org/network/1208920.CONE_0474 | Molecular chaperone HscA; Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.07; Protein involved in unfolded protein binding; Belongs to the heat shock protei [...] |
| CONE_0476 protein network | https://string-db.org/network/1208920.CONE_0476 | Ferredoxin, 2Fe-2S 2e-39; Energy production and conversion; SecretomeP prediction: 0.37; Protein involved in 2 iron, 2 sulfur cluster binding. |
| lysS protein network | https://string-db.org/network/1208920.CONE_0477 | lysyl-tRNA synthetase; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.1; Protein involved in metal ion binding; Belongs to the class-II aminoacyl-tRNA synthetase family [...] |
| prfB protein network | https://string-db.org/network/1208920.CONE_0478 | Peptide chain release factor RF-2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. |
| queE protein network | https://string-db.org/network/1208920.CONE_0479 | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to [...] |
| tadA protein network | https://string-db.org/network/1208920.CONE_0482 | Cytosine/adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. |
| CONE_0483 protein network | https://string-db.org/network/1208920.CONE_0483 | Hypothetical protein; Function unknown; SecretomeP prediction: 0.06. |
| CONE_0484 protein network | https://string-db.org/network/1208920.CONE_0484 | Thioredoxin; Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.14; Protein involved in cell redox homeostasis and oxidation-reduction process; Belongs to the [...] |
| tsaD protein network | https://string-db.org/network/1208920.CONE_0486 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in t [...] |
| plsY protein network | https://string-db.org/network/1208920.CONE_0487 | Glycerol-3-phosphate acyltransferase PlsY; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme [...] |
| surE protein network | https://string-db.org/network/1208920.CONE_0488 | 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. |
| CONE_0489 protein network | https://string-db.org/network/1208920.CONE_0489 | Lipoprotein NlpD; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.07; Protein involved in cell wall macromolecule catabolic process. |
| CONE_0491 protein network | https://string-db.org/network/1208920.CONE_0491 | TrmA family RNA methyltransferase; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.04; Protein involved in transferase activity and 4 iron, 4 sulfur cluster binding; Bel [...] |
| CONE_0492 protein network | https://string-db.org/network/1208920.CONE_0492 | SecretomeP prediction: 0.09; Protein involved in isomerase activity. |
| CONE_0493 protein network | https://string-db.org/network/1208920.CONE_0493 | N6-adenine-specific methylase; DNA replication, recombination, and repair; SecretomeP prediction: 0.54; Protein involved in methylation. |
| CONE_0494 protein network | https://string-db.org/network/1208920.CONE_0494 | Fused signal recognition particle receptor; Intracellular trafficking and secretion; SecretomeP prediction: 0.33; Protein involved in nucleoside-triphosphatase activity and cell division. |
| CONE_0495 protein network | https://string-db.org/network/1208920.CONE_0495 | 3,4-dihydroxy 2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. |
| ribH protein network | https://string-db.org/network/1208920.CONE_0496 | Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is t [...] |
| nusB protein network | https://string-db.org/network/1208920.CONE_0497 | N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of t [...] |
| CONE_0498 protein network | https://string-db.org/network/1208920.CONE_0498 | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). |
| CONE_0499 protein network | https://string-db.org/network/1208920.CONE_0499 | Orotidine-5'-phosphate decarboxylase; Nucleotide transport and metabolism; SecretomeP prediction: 0.13; Protein involved in carboxy-lyase activity. |
| CONE_0500 protein network | https://string-db.org/network/1208920.CONE_0500 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cell [...] |
| rpoZ protein network | https://string-db.org/network/1208920.CONE_0501 | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alp [...] |
| gmk protein network | https://string-db.org/network/1208920.CONE_0502 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. |
| amn protein network | https://string-db.org/network/1208920.CONE_0503 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. |
| CONE_0504 protein network | https://string-db.org/network/1208920.CONE_0504 | Exodeoxyribonuclease III; DNA replication, recombination, and repair; SecretomeP prediction: 0.08; Protein involved in hydrolase activity and DNA repair. |
| rpsT protein network | https://string-db.org/network/1208920.CONE_0505 | Small subunit ribosomal protein S20; Binds directly to 16S ribosomal RNA. |
| murJ protein network | https://string-db.org/network/1208920.CONE_0507 | Virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. |
| adk protein network | https://string-db.org/network/1208920.CONE_0508 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...] |
| xseA protein network | https://string-db.org/network/1208920.CONE_0513 | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucl [...] |
| CONE_0514 protein network | https://string-db.org/network/1208920.CONE_0514 | Fe-Mn family superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase fam [...] |
| CONE_0515 protein network | https://string-db.org/network/1208920.CONE_0515 | CspA family beta-ribbon cold shock protein; Transcription; SecretomeP prediction: 0.87; Protein involved in regulation of transcription, DNA-dependent. |
| CONE_0516 protein network | https://string-db.org/network/1208920.CONE_0516 | Hypothetical protein of the DUF526 family; Function unknown; SecretomeP prediction: 0.07. |
| rpmI protein network | https://string-db.org/network/1208920.CONE_0517 | Large subunit ribosomal protein L35; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.8; Belongs to the bacterial ribosomal protein bL35 family. |
| rplT protein network | https://string-db.org/network/1208920.CONE_0518 | Large subunit ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthes [...] |
| pheS protein network | https://string-db.org/network/1208920.CONE_0519 | phenylalanyl-tRNA synthetase alpha chain; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.09; Protein involved in ligase activity and phenylalanyl-tRNA aminoacylation; B [...] |
| pheT protein network | https://string-db.org/network/1208920.CONE_0520 | phenylalanyl-tRNA synthetase beta chain; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.09; Protein involved in ligase activity; Belongs to the phenylalanyl-tRNA synthe [...] |
| CONE_0521 protein network | https://string-db.org/network/1208920.CONE_0521 | Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tra [...] |
| CONE_0522 protein network | https://string-db.org/network/1208920.CONE_0522 | MerR superfamily transcription regulator; Transcription; SecretomeP prediction: 0.05; Protein involved in regulation of transcription, DNA-dependent. |
| CONE_0523 protein network | https://string-db.org/network/1208920.CONE_0523 | Hypothetical protein; SecretomeP prediction: 0.1. |
| folD protein network | https://string-db.org/network/1208920.CONE_0524 | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofola [...] |
| CONE_0525 protein network | https://string-db.org/network/1208920.CONE_0525 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). |
| CONE_0526 protein network | https://string-db.org/network/1208920.CONE_0526 | Pyruvate dehydrogenase E2 component; Energy production and conversion; SecretomeP prediction: 0.3. |
| CONE_0528 protein network | https://string-db.org/network/1208920.CONE_0528 | Dihydrolipoamide dehydrogenase; Energy production and conversion; SecretomeP prediction: 0.06; Protein involved in oxidation-reduction process. |
| CONE_0529 protein network | https://string-db.org/network/1208920.CONE_0529 | Mechanosensitive channel protein; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.14; Protein involved in transmembrane transport. |
| nadE protein network | https://string-db.org/network/1208920.CONE_0530 | Glutamine-hydrolysing NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. |
| CONE_0531 protein network | https://string-db.org/network/1208920.CONE_0531 | single-stranded-DNA-specific exonuclease; DNA replication, recombination, and repair; SecretomeP prediction: 0.15; Protein involved in manganese ion binding. |
| CONE_0533 protein network | https://string-db.org/network/1208920.CONE_0533 | Hypothetical protein; Function unknown; SecretomeP prediction: 0.08. |
| CONE_0534 protein network | https://string-db.org/network/1208920.CONE_0534 | Lipoprotein-releasing system permease protein; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.08. |
| lolD protein network | https://string-db.org/network/1208920.CONE_0535 | Lipoprotein-releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transpor [...] |
| CONE_0537 protein network | https://string-db.org/network/1208920.CONE_0537 | TatD DNase family protein; DNA replication, recombination, and repair; SecretomeP prediction: 0.1; Protein involved in endodeoxyribonuclease activity, producing 5'-phosphomonoesters. |
| purL protein network | https://string-db.org/network/1208920.CONE_0540 | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ri [...] |
| rph protein network | https://string-db.org/network/1208920.CONE_0541 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucl [...] |
| CONE_0542 protein network | https://string-db.org/network/1208920.CONE_0542 | Dihydrofolate synthase/folylpolyglutamate synthase; Coenzyme metabolism; SecretomeP prediction: 0.04; Protein involved in ligase activity; Belongs to the folylpolyglutamate synthase family. |
| CONE_0543 protein network | https://string-db.org/network/1208920.CONE_0543 | Colicin V production protein CvpA; General function prediction only; SecretomeP prediction: 0.43. |
| purF protein network | https://string-db.org/network/1208920.CONE_0544 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine p [...] |
| CONE_0545 protein network | https://string-db.org/network/1208920.CONE_0545 | Disulfide bond formation protein DsbB; Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.24; Protein involved in oxidation-reduction process. |
| CONE_0546 protein network | https://string-db.org/network/1208920.CONE_0546 | Multiple antibiotic resistance protein; Intracellular trafficking and secretion; SecretomeP prediction: 0.25. |
| map protein network | https://string-db.org/network/1208920.CONE_0548 | Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharge [...] |
| rpsB protein network | https://string-db.org/network/1208920.CONE_0549 | Small subunit ribosomal protein S2; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.08; Belongs to the universal ribosomal protein uS2 family. |
| tsf protein network | https://string-db.org/network/1208920.CONE_0551 | Elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on [...] |
| pyrH protein network | https://string-db.org/network/1208920.CONE_0552 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. |
| frr protein network | https://string-db.org/network/1208920.CONE_0553 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...] |
| CONE_0554 protein network | https://string-db.org/network/1208920.CONE_0554 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. |
| CONE_0555 protein network | https://string-db.org/network/1208920.CONE_0555 | Phosphatidate cytidylyltransferase; Lipid metabolism; SecretomeP prediction: 0.4; Protein involved in nucleotidyltransferase activity; Belongs to the CDS family. |
| dxr protein network | https://string-db.org/network/1208920.CONE_0557 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Be [...] |
| bamA protein network | https://string-db.org/network/1208920.CONE_0559 | Outer membrane protein assembly complex YaeT; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. |
| CONE_0560 protein network | https://string-db.org/network/1208920.CONE_0560 | Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.07; Protein involved in protein binding; Belongs to the skp family. |
| fabZ protein network | https://string-db.org/network/1208920.CONE_0561 | 3R-hydroxymyristoyl ACP dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-h [...] |
| rnhB protein network | https://string-db.org/network/1208920.CONE_0562 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. |
| CONE_0563 protein network | https://string-db.org/network/1208920.CONE_0563 | Conserved hypothetical protein of the DUF299 family; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its [...] |
| CONE_0565 protein network | https://string-db.org/network/1208920.CONE_0565 | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. |
| smpB protein network | https://string-db.org/network/1208920.CONE_0567 | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...] |
| CONE_0568 protein network | https://string-db.org/network/1208920.CONE_0568 | COQ10p-like coenzyme Q-binding protein; Lipid metabolism; SecretomeP prediction: 0.18. |
| CONE_0569 protein network | https://string-db.org/network/1208920.CONE_0569 | Hypothetical protein; Function unknown; SecretomeP prediction: 0.07; Belongs to the UPF0125 (RnfH) family. |
| CONE_0570 protein network | https://string-db.org/network/1208920.CONE_0570 | Nodulin-21-like protein; Function unknown; SecretomeP prediction: 0.17. |
| mltG protein network | https://string-db.org/network/1208920.CONE_0571 | YceG-like protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. |
| tmk protein network | https://string-db.org/network/1208920.CONE_0572 | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. |
| CONE_0573 protein network | https://string-db.org/network/1208920.CONE_0573 | DNA polymerase III subunit delta; DNA replication, recombination, and repair; SecretomeP prediction: 0.24; Protein involved in nucleotidyltransferase activity. |
| CONE_0574 protein network | https://string-db.org/network/1208920.CONE_0574 | TatD DNase family protein; DNA replication, recombination, and repair; SecretomeP prediction: 0.15; Protein involved in endodeoxyribonuclease activity, producing 5'-phosphomonoesters. |
| CONE_0575 protein network | https://string-db.org/network/1208920.CONE_0575 | Lipoate-protein ligase A; Coenzyme metabolism; SecretomeP prediction: 0.11; Protein involved in ligase activity and cellular protein modification process. |
| CONE_0576 protein network | https://string-db.org/network/1208920.CONE_0576 | SecretomeP prediction: 0.03; Protein involved in ligase activity. |
| guaA protein network | https://string-db.org/network/1208920.CONE_0577 | Glutamine-hydrolysing GMP synthase; Catalyzes the synthesis of GMP from XMP. |
| guaB protein network | https://string-db.org/network/1208920.CONE_0578 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleoti [...] |
| CONE_0579 protein network | https://string-db.org/network/1208920.CONE_0579 | Conserved hypothetical protein of the DUF466 family; Function unknown; SecretomeP prediction: 0.17. |
| CONE_0580 protein network | https://string-db.org/network/1208920.CONE_0580 | Carbon starvation protein; Signal transduction mechanisms; SecretomeP prediction: 0.35. |
| CONE_0581 protein network | https://string-db.org/network/1208920.CONE_0581 | ATP-dependent DNA helicase RecG; DNA replication, recombination, and repair / Transcription; SecretomeP prediction: 0.15; Protein involved in hydrolase activity. |
| CONE_0582 protein network | https://string-db.org/network/1208920.CONE_0582 | TdcF protein; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.49. |
| CONE_0583 protein network | https://string-db.org/network/1208920.CONE_0583 | ferredoxin--NADP+ reductase; Energy production and conversion; SecretomeP prediction: 0.04; Protein involved in oxidation-reduction process. |
| CONE_0584 protein network | https://string-db.org/network/1208920.CONE_0584 | Oxygen-independent coproporphyrinogen III oxidase hemN; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. B [...] |
| CONE_0585 protein network | https://string-db.org/network/1208920.CONE_0585 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleo [...] |
| CONE_0586 protein network | https://string-db.org/network/1208920.CONE_0586 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. |
| CONE_0587 protein network | https://string-db.org/network/1208920.CONE_0587 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. |
| CONE_0588 protein network | https://string-db.org/network/1208920.CONE_0588 | TrmH family RNA methyltransferase; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.09; Protein involved in transferase activity; Belongs to the class IV-like SAM-binding [...] |
| rnr protein network | https://string-db.org/network/1208920.CONE_0589 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. |
| CONE_0590 protein network | https://string-db.org/network/1208920.CONE_0590 | Adenylosuccinate lyase; Nucleotide transport and metabolism; SecretomeP prediction: 0.18; Protein involved in (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate AMP-lyase (f [...] |
| mnmA protein network | https://string-db.org/network/1208920.CONE_0592 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. |
| CONE_0593 protein network | https://string-db.org/network/1208920.CONE_0593 | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP [...] |
| CONE_0594 protein network | https://string-db.org/network/1208920.CONE_0594 | TldD protein; General function prediction only; SecretomeP prediction: 0.49; Protein involved in hydrolase activity. |
| CONE_0596 protein network | https://string-db.org/network/1208920.CONE_0596 | Amino acid transport and metabolism; SecretomeP prediction: 0.18; Protein involved in hydrolase activity. |
| fbp protein network | https://string-db.org/network/1208920.CONE_0598 | Carbohydrate transport and metabolism; SecretomeP prediction: 0.16; Protein involved in phosphoric ester hydrolase activity; Belongs to the FBPase class 1 family. |
| CONE_0599 protein network | https://string-db.org/network/1208920.CONE_0599 | Homoserine dehydrogenase; Amino acid transport and metabolism; SecretomeP prediction: 0.06; Protein involved in oxidation-reduction process. |
| CONE_0600 protein network | https://string-db.org/network/1208920.CONE_0600 | Conserved hypothetical protein of the DUF498/DUF598 family; Function unknown; SecretomeP prediction: 0.08. |
| CONE_0602 protein network | https://string-db.org/network/1208920.CONE_0602 | 4-hydroxythreonine-4-phosphate dehydrogenase; Coenzyme metabolism; SecretomeP prediction: 0.07; Protein involved in oxidation-reduction process; Belongs to the PdxA family. |
| CONE_0603 protein network | https://string-db.org/network/1208920.CONE_0603 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...] |
| rplI protein network | https://string-db.org/network/1208920.CONE_0604 | Large subunit ribosomal protein L9; Binds to the 23S rRNA. |
| rpsR protein network | https://string-db.org/network/1208920.CONE_0605 | Small subunit ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacteri [...] |
| CONE_0606 protein network | https://string-db.org/network/1208920.CONE_0606 | DNA replication, recombination, and repair; SecretomeP prediction: 0.2; Protein involved in single-stranded DNA binding. |
| rpsF protein network | https://string-db.org/network/1208920.CONE_0607 | Small subunit ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. |
| folE2 protein network | https://string-db.org/network/1208920.CONE_0608 | GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. |
| dxs protein network | https://string-db.org/network/1208920.CONE_0609 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (D [...] |
| CONE_0610 protein network | https://string-db.org/network/1208920.CONE_0610 | Farnesyl diphosphate synthase; Coenzyme metabolism; SecretomeP prediction: 0.25; Protein involved in transferase activity; Belongs to the FPP/GGPP synthase family. |
| CONE_0611 protein network | https://string-db.org/network/1208920.CONE_0611 | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucl [...] |
| rpoD protein network | https://string-db.org/network/1208920.CONE_0612 | RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is th [...] |
| dnaG protein network | https://string-db.org/network/1208920.CONE_0613 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. |
| rpsU protein network | https://string-db.org/network/1208920.CONE_0614 | Small subunit ribosomal protein S21; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.11; Belongs to the bacterial ribosomal protein bS21 family. |
| purA protein network | https://string-db.org/network/1208920.CONE_0615 | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the [...] |
| CONE_0619 protein network | https://string-db.org/network/1208920.CONE_0619 | Membrane protease subunit HflC; HflC and HflK could regulate a protease. |
| CONE_0621 protein network | https://string-db.org/network/1208920.CONE_0621 | Membrane protease subunit HflK; HflC and HflK could encode or regulate a protease. |
| hflX protein network | https://string-db.org/network/1208920.CONE_0622 | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPa [...] |
| hfq protein network | https://string-db.org/network/1208920.CONE_0623 | Host factor-I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes [...] |
| der protein network | https://string-db.org/network/1208920.CONE_0624 | GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase [...] |
| CONE_0625 protein network | https://string-db.org/network/1208920.CONE_0625 | Hypothetical protein; Function unknown; SecretomeP prediction: 0.08. |
| hisS protein network | https://string-db.org/network/1208920.CONE_0626 | histidyl-tRNA synthetase; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.07; Protein involved in ligase activity. |
| ispG protein network | https://string-db.org/network/1208920.CONE_0627 | (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG f [...] |
| rlmN protein network | https://string-db.org/network/1208920.CONE_0629 | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial [...] |
| ndk protein network | https://string-db.org/network/1208920.CONE_0630 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, [...] |
| valS protein network | https://string-db.org/network/1208920.CONE_0632 | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...] |
| trmD protein network | https://string-db.org/network/1208920.CONE_0633 | tRNA (guanine-N1-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. |
| rimM protein network | https://string-db.org/network/1208920.CONE_0634 | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19 [...] |
| rpsP protein network | https://string-db.org/network/1208920.CONE_0635 | Small subunit ribosomal protein S16; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.56; Belongs to the bacterial ribosomal protein bS16 family. |
| CONE_0636 protein network | https://string-db.org/network/1208920.CONE_0636 | SirA-like protein; Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.05; Protein involved in sulfurtransferase activity and oxidation-reduction process; Belon [...] |
| alaS protein network | https://string-db.org/network/1208920.CONE_0637 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...] |
| CONE_0638 protein network | https://string-db.org/network/1208920.CONE_0638 | CDP-4-dehydro-6-deoxyglucose reductase; Coenzyme metabolism / Energy production and conversion; SecretomeP prediction: 0.04; Protein involved in oxidation-reduction process. |
| rho protein network | https://string-db.org/network/1208920.CONE_0639 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...] |
| queH protein network | https://string-db.org/network/1208920.CONE_0640 | Conserved hypothetical protein of the DUF208 family; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tR [...] |
| CONE_0641 protein network | https://string-db.org/network/1208920.CONE_0641 | Putative divalent heavy-metal cations transporter; Inorganic ion transport and metabolism; SecretomeP prediction: 0.27; Protein involved in transmembrane transport. |
| polA protein network | https://string-db.org/network/1208920.CONE_0642 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. |
| CONE_0643 protein network | https://string-db.org/network/1208920.CONE_0643 | GTP-binding protein; Signal transduction mechanisms; SecretomeP prediction: 0.1; Protein involved in oxidation-reduction process. |
| truB protein network | https://string-db.org/network/1208920.CONE_0644 | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. |
| rbfA protein network | https://string-db.org/network/1208920.CONE_0645 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...] |
| infB protein network | https://string-db.org/network/1208920.CONE_0646 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...] |
| nusA protein network | https://string-db.org/network/1208920.CONE_0647 | N utilization substance protein A; Participates in both transcription termination and antitermination. |
| rimP protein network | https://string-db.org/network/1208920.CONE_0648 | Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. |
| CONE_0649 protein network | https://string-db.org/network/1208920.CONE_0649 | Ribosomal large subunit pseudouridine synthase B; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.54; Protein involved in intramolecular transferase activity; Belongs to [...] |
| ispH protein network | https://string-db.org/network/1208920.CONE_0650 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethyl [...] |
| CONE_0651 protein network | https://string-db.org/network/1208920.CONE_0651 | Large subunit ribosomal protein L31; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.55; Belongs to the bacterial ribosomal protein bL31 family. |
| CONE_0653 protein network | https://string-db.org/network/1208920.CONE_0653 | MATE family multidrug resistance protein. |
| orn protein network | https://string-db.org/network/1208920.CONE_0655 | Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. |
| rsgA protein network | https://string-db.org/network/1208920.CONE_0656 | Ribosome biogenesis GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play [...] |
| rplS protein network | https://string-db.org/network/1208920.CONE_0658 | Large subunit ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. |
| CONE_0659 protein network | https://string-db.org/network/1208920.CONE_0659 | Electron transfer flavoprotein alpha subunit; Energy production and conversion; SecretomeP prediction: 0.13; Protein involved in flavin adenine dinucleotide binding. |
| CONE_0661 protein network | https://string-db.org/network/1208920.CONE_0661 | Electron transfer flavoprotein beta subunit; Energy production and conversion; SecretomeP prediction: 0.08; Protein involved in electron carrier activity. |
| CONE_0662 protein network | https://string-db.org/network/1208920.CONE_0662 | Histone deacetylase-like protein; Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism; SecretomeP prediction: 0.07; Protein involved in acetylspermidi [...] |
| CONE_0664 protein network | https://string-db.org/network/1208920.CONE_0664 | Integration host factor subunit beta; DNA replication, recombination, and repair; SecretomeP prediction: 0.35; Protein involved in DNA binding and regulation of transcription, DNA-dependent; Belo [...] |
| CONE_0665 protein network | https://string-db.org/network/1208920.CONE_0665 | Small subunit ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. |
| cmk protein network | https://string-db.org/network/1208920.CONE_0666 | Cytidylate kinase; Nucleotide transport and metabolism; SecretomeP prediction: 0.07; Protein involved in transferase activity. |
| aroA protein network | https://string-db.org/network/1208920.CONE_0669 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...] |
| CONE_0670 protein network | https://string-db.org/network/1208920.CONE_0670 | Prephenate dehydrogenase; Amino acid transport and metabolism; SecretomeP prediction: 0.11; Protein involved in oxidation-reduction process. |
| hisC-2 protein network | https://string-db.org/network/1208920.CONE_0671 | Histidinol-phosphate aminotransferase; Amino acid transport and metabolism; SecretomeP prediction: 0.08; Protein involved in pyridoxal phosphate binding; Belongs to the class-II pyridoxal-phospha [...] |
| CONE_0672 protein network | https://string-db.org/network/1208920.CONE_0672 | Prephenate dehydratase; Amino acid transport and metabolism; SecretomeP prediction: 0.09; Protein involved in chorismate metabolic process. |
| serC protein network | https://string-db.org/network/1208920.CONE_0673 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belon [...] |
| gyrA protein network | https://string-db.org/network/1208920.CONE_0674 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...] |
| CONE_0675 protein network | https://string-db.org/network/1208920.CONE_0675 | OOP family OmpA-OmpF porin; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.89. |
| ubiG protein network | https://string-db.org/network/1208920.CONE_0676 | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG [...] |
| CONE_0677 protein network | https://string-db.org/network/1208920.CONE_0677 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. |
| trpS protein network | https://string-db.org/network/1208920.CONE_0679 | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. |
| CONE_0680 protein network | https://string-db.org/network/1208920.CONE_0680 | Dihydrolipoamide dehydrogenase; Energy production and conversion; SecretomeP prediction: 0.07; Protein involved in oxidation-reduction process. |
| CONE_0681 protein network | https://string-db.org/network/1208920.CONE_0681 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and [...] |
| CONE_0682 protein network | https://string-db.org/network/1208920.CONE_0682 | 2-oxoglutarate dehydrogenase E1 component; Energy production and conversion; SecretomeP prediction: 0.32; Protein involved in oxidation-reduction process. |
| CONE_0683 protein network | https://string-db.org/network/1208920.CONE_0683 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Energy production and conversion; SecretomeP prediction: 0.12; Protein involved in oxidation-reduction process. |
| CONE_0684 protein network | https://string-db.org/network/1208920.CONE_0684 | N6-adenine-specific DNA methylase; DNA replication, recombination, and repair; SecretomeP prediction: 0.13; Protein involved in methylation; Belongs to the methyltransferase superfamily. |
| eno protein network | https://string-db.org/network/1208920.CONE_0685 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. |
| pyrG protein network | https://string-db.org/network/1208920.CONE_0688 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the fo [...] |
| CONE_0689 protein network | https://string-db.org/network/1208920.CONE_0689 | Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. |
| CONE_0690 protein network | https://string-db.org/network/1208920.CONE_0690 | acetyl-CoA synthetase; Lipid metabolism; SecretomeP prediction: 0.13; Protein involved in ligase activity. |
| CONE_0691 protein network | https://string-db.org/network/1208920.CONE_0691 | Glc operon protein GlcG; General function prediction only; SecretomeP prediction: 0.06. |
| CONE_0692 protein network | https://string-db.org/network/1208920.CONE_0692 | NlpC/P60 family protein; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.44. |
| pepA protein network | https://string-db.org/network/1208920.CONE_0694 | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. |
| CONE_0695 protein network | https://string-db.org/network/1208920.CONE_0695 | DNA polymerase III subunit chi; DNA replication, recombination, and repair; SecretomeP prediction: 0.16; Protein involved in nucleotidyltransferase activity and DNA replication. |
| CONE_0697 protein network | https://string-db.org/network/1208920.CONE_0697 | Inner membrane protein YccA; General function prediction only; SecretomeP prediction: 0.4; Belongs to the BI1 family. |
| recO protein network | https://string-db.org/network/1208920.CONE_0698 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. |
| era protein network | https://string-db.org/network/1208920.CONE_0699 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly als [...] |
| rnc protein network | https://string-db.org/network/1208920.CONE_0701 | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...] |
| CONE_0702 protein network | https://string-db.org/network/1208920.CONE_0702 | Signal peptidase I; Intracellular trafficking and secretion; SecretomeP prediction: 0.1; Protein involved in hydrolase activity; Belongs to the peptidase S26 family. |
| lepA protein network | https://string-db.org/network/1208920.CONE_0704 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...] |
| CONE_0705 protein network | https://string-db.org/network/1208920.CONE_0705 | Serine protease; Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.06; Protein involved in peptidase activity and hydrolase activity; Belongs to the peptidase [...] |
| CONE_0706 protein network | https://string-db.org/network/1208920.CONE_0706 | 3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. |
| acpP protein network | https://string-db.org/network/1208920.CONE_0707 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. |
| CONE_0708 protein network | https://string-db.org/network/1208920.CONE_0708 | 3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cy [...] |
| CONE_0709 protein network | https://string-db.org/network/1208920.CONE_0709 | [acyl-carrier-protein] S-malonyltransferase; Lipid metabolism; SecretomeP prediction: 0.18; Protein involved in transferase activity and fatty acid biosynthetic process. |
| fabH protein network | https://string-db.org/network/1208920.CONE_0710 | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first [...] |
| plsX protein network | https://string-db.org/network/1208920.CONE_0711 | Glycerol-3-phosphate acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty a [...] |
| rpmF protein network | https://string-db.org/network/1208920.CONE_0712 | Large subunit ribosomal protein L32; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.85; Belongs to the bacterial ribosomal protein bL32 family. |
| CONE_0713 protein network | https://string-db.org/network/1208920.CONE_0713 | Hypothetical protein; SecretomeP prediction: 0.32. |
| CONE_0714 protein network | https://string-db.org/network/1208920.CONE_0714 | Septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modi [...] |
| CONE_0715 protein network | https://string-db.org/network/1208920.CONE_0715 | Putative methyltransferase; General function prediction only; SecretomeP prediction: 0.12; Protein involved in transferase activity. |
| CONE_0716 protein network | https://string-db.org/network/1208920.CONE_0716 | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. |
| rne protein network | https://string-db.org/network/1208920.CONE_0717 | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation [...] |
| accD protein network | https://string-db.org/network/1208920.CONE_0719 | acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrie [...] |
| trpA protein network | https://string-db.org/network/1208920.CONE_0720 | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. |
| trpB protein network | https://string-db.org/network/1208920.CONE_0722 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. |
| CONE_0723 protein network | https://string-db.org/network/1208920.CONE_0723 | GTP pyrophosphokinase; Signal transduction mechanisms / Transcription; SecretomeP prediction: 0.16; Protein involved in transferase activity. |
| pncB protein network | https://string-db.org/network/1208920.CONE_0724 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase [...] |
| CONE_0725 protein network | https://string-db.org/network/1208920.CONE_0725 | Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. |
| CONE_0726 protein network | https://string-db.org/network/1208920.CONE_0726 | ferredoxin--NADP+ reductase; Energy production and conversion; SecretomeP prediction: 0.06; Protein involved in oxidation-reduction process. |
| CONE_0727 protein network | https://string-db.org/network/1208920.CONE_0727 | Electron transport complex protein RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferred [...] |
| nth protein network | https://string-db.org/network/1208920.CONE_0728 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- [...] |
| CONE_0729 protein network | https://string-db.org/network/1208920.CONE_0729 | Intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. |
| CONE_0730 protein network | https://string-db.org/network/1208920.CONE_0730 | BolA protein; Signal transduction mechanisms; SecretomeP prediction: 0.05; Belongs to the BolA/IbaG family. |
| CONE_0731 protein network | https://string-db.org/network/1208920.CONE_0731 | Peptidyl-prolyl cis-trans isomerase C; Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.06; Protein involved in isomerase activity. |
| ligA protein network | https://string-db.org/network/1208920.CONE_0734 | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energ [...] |
| CONE_0735 protein network | https://string-db.org/network/1208920.CONE_0735 | Hypothetical protein; SecretomeP prediction: 0.05. |
| CONE_0737 protein network | https://string-db.org/network/1208920.CONE_0737 | Lysophospholipid transporter LplT; SecretomeP prediction: 0.21; Protein involved in transmembrane transport. |
| CONE_0738 protein network | https://string-db.org/network/1208920.CONE_0738 | DNA polymerase bacteriophage-type; DNA replication, recombination, and repair; SecretomeP prediction: 0.06; Protein involved in hydrolase activity, acting on glycosyl bonds. |
| CONE_0739 protein network | https://string-db.org/network/1208920.CONE_0739 | Fused YeaZ/rimI ribosomal protein N-acetyltransferase; Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.2; Protein involved in transferase activity. |
| CONE_0740 protein network | https://string-db.org/network/1208920.CONE_0740 | Alkyl hydroperoxide reductase subunit C; Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.07; Protein involved in cell redox homeostasis and oxidation-reduct [...] |
| ispF protein network | https://string-db.org/network/1208920.CONE_0742 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...] |
| ispD protein network | https://string-db.org/network/1208920.CONE_0743 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). |
| mfd protein network | https://string-db.org/network/1208920.CONE_0744 | Superfamily II transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and i [...] |
| nuoN protein network | https://string-db.org/network/1208920.CONE_0747 | NADH dehydrogenase I subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in [...] |
| CONE_0749 protein network | https://string-db.org/network/1208920.CONE_0749 | NADH dehydrogenase I subunit M; Energy production and conversion; SecretomeP prediction: 0.38; Protein involved in oxidation-reduction process. |
| CONE_0751 protein network | https://string-db.org/network/1208920.CONE_0751 | NADH dehydrogenase I subunit L; Energy production and conversion / Inorganic ion transport and metabolism; SecretomeP prediction: 0.37; Protein involved in oxidation-reduction process. |
| nuoK protein network | https://string-db.org/network/1208920.CONE_0752 | NADH dehydrogenase I subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in [...] |
| CONE_0753 protein network | https://string-db.org/network/1208920.CONE_0753 | NADH dehydrogenase I subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocatio [...] |
| nuoI protein network | https://string-db.org/network/1208920.CONE_0754 | NADH dehydrogenase I subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in [...] |
| nuoH protein network | https://string-db.org/network/1208920.CONE_0755 | NADH dehydrogenase I subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in [...] |
| CONE_0757 protein network | https://string-db.org/network/1208920.CONE_0757 | NADH dehydrogenase I subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocatio [...] |
| CONE_0758 protein network | https://string-db.org/network/1208920.CONE_0758 | NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. |
| CONE_0759 protein network | https://string-db.org/network/1208920.CONE_0759 | NADH dehydrogenase I subunit E; Energy production and conversion; SecretomeP prediction: 0.28; Protein involved in oxidation-reduction process. |
| nuoD protein network | https://string-db.org/network/1208920.CONE_0760 | NADH dehydrogenase I subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in [...] |
| nuoC protein network | https://string-db.org/network/1208920.CONE_0761 | NADH dehydrogenase I subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in [...] |
| nuoB protein network | https://string-db.org/network/1208920.CONE_0762 | NADH dehydrogenase I subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in [...] |
| nuoA protein network | https://string-db.org/network/1208920.CONE_0763 | NADH dehydrogenase I subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in [...] |
| CONE_0764 protein network | https://string-db.org/network/1208920.CONE_0764 | Porin; Cell envelope biogenesis, outer membrane; SecretomeP prediction: 0.89. |
| CONE_0765 protein network | https://string-db.org/network/1208920.CONE_0765 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. |
| tpiA protein network | https://string-db.org/network/1208920.CONE_0766 | Triosephosphate isomerase TIM; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to [...] |
| CONE_0767 protein network | https://string-db.org/network/1208920.CONE_0767 | NADPH2:quinone reductase; Energy production and conversion / General function prediction only; SecretomeP prediction: 0.08; Protein involved in oxidation-reduction process. |
| pnp protein network | https://string-db.org/network/1208920.CONE_0768 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. |
| rpsO protein network | https://string-db.org/network/1208920.CONE_0769 | Small subunit ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. |
| ilvC protein network | https://string-db.org/network/1208920.CONE_0770 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...] |
| CONE_0771 protein network | https://string-db.org/network/1208920.CONE_0771 | Acetolactate synthase I/III small subunit; Amino acid transport and metabolism; SecretomeP prediction: 0.15; Protein involved in transferase activity. |
| CONE_0772 protein network | https://string-db.org/network/1208920.CONE_0772 | Acetolactate synthase I/II/III large subunit; Acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabo [...] |
| serS protein network | https://string-db.org/network/1208920.CONE_0775 | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...] |
| CONE_0776 protein network | https://string-db.org/network/1208920.CONE_0776 | Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue [...] |
| CONE_0778 protein network | https://string-db.org/network/1208920.CONE_0778 | S-DNA-T family DNA segregation ATPase FtsK/SpoIIIE; Cell division and chromosome partitioning; SecretomeP prediction: 0.16; Protein involved in cell division. |
| CONE_0779 protein network | https://string-db.org/network/1208920.CONE_0779 | Thioredoxin reductase (NADPH); Posttranslational modification, protein turnover, chaperones; SecretomeP prediction: 0.19; Protein involved in oxidation-reduction process. |
| CONE_0780 protein network | https://string-db.org/network/1208920.CONE_0780 | Small MutS-related protein; Function unknown; SecretomeP prediction: 0.09. |
| CONE_0781 protein network | https://string-db.org/network/1208920.CONE_0781 | SMR family small multidrug resistance protein; Inorganic ion transport and metabolism; SecretomeP prediction: 0.08. |
| CONE_0782 protein network | https://string-db.org/network/1208920.CONE_0782 | Arginine:ornithine antiporter; Amino acid transport and metabolism; SecretomeP prediction: 0.1; Protein involved in transmembrane transport. |
| CONE_0784 protein network | https://string-db.org/network/1208920.CONE_0784 | Conserved hypothetical protein of the DUF1841 family; SecretomeP prediction: 0.4. |
| dnaJ protein network | https://string-db.org/network/1208920.CONE_0785 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in a [...] |
| dnaK protein network | https://string-db.org/network/1208920.CONE_0786 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. |
| grpE protein network | https://string-db.org/network/1208920.CONE_0787 | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is [...] |
| hemH protein network | https://string-db.org/network/1208920.CONE_0788 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. |
| nadK protein network | https://string-db.org/network/1208920.CONE_0791 | NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of [...] |
| CONE_0792 protein network | https://string-db.org/network/1208920.CONE_0792 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. |
| dapB protein network | https://string-db.org/network/1208920.CONE_0794 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. |
| murB protein network | https://string-db.org/network/1208920.CONE_0795 | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. |
| pyrD protein network | https://string-db.org/network/1208920.CONE_0796 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. |
| CONE_0797 protein network | https://string-db.org/network/1208920.CONE_0797 | Thioredoxin domain protein; Posttranslational modification, protein turnover, chaperones / Energy production and conversion; SecretomeP prediction: 0.04; Protein involved in cell redox homeostasi [...] |
| CONE_0798 protein network | https://string-db.org/network/1208920.CONE_0798 | ATP-dependent RNA helicase RhlE; DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.05; Protein involved in hyd [...] |
| CONE_0799 protein network | https://string-db.org/network/1208920.CONE_0799 | 2-octaprenyl-6-methoxyphenol hydroxylase; Coenzyme metabolism / Energy production and conversion; SecretomeP prediction: 0.05; Protein involved in oxidation-reduction process. |
| CONE_0800 protein network | https://string-db.org/network/1208920.CONE_0800 | Fis family transcriptional regulator, factor for inversion; Transcription / DNA replication, recombination, and repair; SecretomeP prediction: 0.08; Protein involved in regulation of transcriptio [...] |
| purH protein network | https://string-db.org/network/1208920.CONE_0801 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Nucleotide transport and metabolism; SecretomeP prediction: 0.07; Protein involved in hydrolase activity. |
| ruvC protein network | https://string-db.org/network/1208920.CONE_0802 | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to st [...] |
| ruvA protein network | https://string-db.org/network/1208920.CONE_0803 | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand [...] |
| ruvB protein network | https://string-db.org/network/1208920.CONE_0804 | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand [...] |
| CONE_0806 protein network | https://string-db.org/network/1208920.CONE_0806 | glutaminyl-tRNA synthetase; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.18; Protein involved in tRNA aminoacylation. |
| minC protein network | https://string-db.org/network/1208920.CONE_0807 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments tha [...] |
| CONE_0808 protein network | https://string-db.org/network/1208920.CONE_0808 | Septum site-determining protein MinD; Cell division and chromosome partitioning; SecretomeP prediction: 0.05; Protein involved in ATPase activity. |
| minE protein network | https://string-db.org/network/1208920.CONE_0809 | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures c [...] |
| CONE_0810 protein network | https://string-db.org/network/1208920.CONE_0810 | Sulfate-transporting ATPase; General function prediction only; SecretomeP prediction: 0.05; Protein involved in nucleoside-triphosphatase activity. |
| CONE_0811 protein network | https://string-db.org/network/1208920.CONE_0811 | Hypothetical protein; SecretomeP prediction: 0.51. |
| CONE_0812 protein network | https://string-db.org/network/1208920.CONE_0812 | Dual-domain excinuclease ABC subunit A uvrA; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition co [...] |
| CONE_0813 protein network | https://string-db.org/network/1208920.CONE_0813 | Uba/ThiF-type NAD/FAD binding protein; Coenzyme metabolism; SecretomeP prediction: 0.12; Protein involved in metabolic process. |
| pdxH protein network | https://string-db.org/network/1208920.CONE_0814 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). |
| CONE_0816 protein network | https://string-db.org/network/1208920.CONE_0816 | Flavin reductase-like protein; General function prediction only; SecretomeP prediction: 0.23; Protein involved in FMN binding and oxidation-reduction process. |
| CONE_0817 protein network | https://string-db.org/network/1208920.CONE_0817 | Putative ATPase or kinase; General function prediction only; SecretomeP prediction: 0.27. |
| mutL protein network | https://string-db.org/network/1208920.CONE_0821 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchm [...] |
| miaA protein network | https://string-db.org/network/1208920.CONE_0822 | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(di [...] |
| purM protein network | https://string-db.org/network/1208920.CONE_0823 | Phosphoribosylformylglycinamidine cyclo-ligase; Nucleotide transport and metabolism; SecretomeP prediction: 0.05; Protein involved in ligase activity. |
| CONE_0824 protein network | https://string-db.org/network/1208920.CONE_0824 | DnaA-like protein; DNA replication, recombination, and repair; SecretomeP prediction: 0.09; Protein involved in nucleoside-triphosphatase activity; Belongs to the DnaA family. |
| CONE_0825 protein network | https://string-db.org/network/1208920.CONE_0825 | HAD-superfamily hydrolase; Amino acid transport and metabolism; SecretomeP prediction: 0.16; Protein involved in phosphatase activity. |
| pcnB protein network | https://string-db.org/network/1208920.CONE_0826 | poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencin [...] |
| CONE_0827 protein network | https://string-db.org/network/1208920.CONE_0827 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Coenzyme metabolism; SecretomeP prediction: 0.04; Protein involved in transferase activity. |
| glyQ protein network | https://string-db.org/network/1208920.CONE_0828 | glycyl-tRNA synthetase alpha chain; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.06; Protein involved in ligase activity. |
| glyS protein network | https://string-db.org/network/1208920.CONE_0829 | glycyl-tRNA synthetase beta chain; Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.21; Protein involved in ligase activity. |
| CONE_0831 protein network | https://string-db.org/network/1208920.CONE_0831 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Lipid metabolism; SecretomeP prediction: 0.06; Protein involved in transferase activity. |
| secA protein network | https://string-db.org/network/1208920.CONE_0832 | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to [...] |
| CONE_0833 protein network | https://string-db.org/network/1208920.CONE_0833 | Hypothetical protein; SecretomeP prediction: 0.3. |
| ftsZ protein network | https://string-db.org/network/1208920.CONE_0835 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...] |
| ddl protein network | https://string-db.org/network/1208920.CONE_0836 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. |
| murC protein network | https://string-db.org/network/1208920.CONE_0837 | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. |
| murG protein network | https://string-db.org/network/1208920.CONE_0839 | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase MurG; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentape [...] |
| murD protein network | https://string-db.org/network/1208920.CONE_0840 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF [...] |
| mraY protein network | https://string-db.org/network/1208920.CONE_0841 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...] |
| murF protein network | https://string-db.org/network/1208920.CONE_0842 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UM [...] |
| rsmH protein network | https://string-db.org/network/1208920.CONE_0843 | S-adenosyl-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. |
| CONE_0844 protein network | https://string-db.org/network/1208920.CONE_0844 | ABC transporter ATP-binding protein; General function prediction only; SecretomeP prediction: 0.11; Protein involved in nucleoside-triphosphatase activity. |
| pyrC protein network | https://string-db.org/network/1208920.CONE_0845 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. |
| CONE_0846 protein network | https://string-db.org/network/1208920.CONE_0846 | Conserved membrane protein; Function unknown; SecretomeP prediction: 0.29. |