Organism Overview: secondary endosymbiont of Ctenarytaina


 
dnaA protein networkhttps://string-db.org/network/1199245.A359_00010Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically doub [...]
A359_00020 protein networkhttps://string-db.org/network/1199245.A359_00020DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadi [...]
gyrB protein networkhttps://string-db.org/network/1199245.A359_00030DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
A359_00040 protein networkhttps://string-db.org/network/1199245.A359_00040TIGR00255 family protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein.
metG protein networkhttps://string-db.org/network/1199245.A359_00060Protein containing C-terminal region/beta chain of methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through [...]
A359_00070 protein networkhttps://string-db.org/network/1199245.A359_00070PFAM: PAP2 superfamily.
smpB protein networkhttps://string-db.org/network/1199245.A359_00090SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
A359_00100 protein networkhttps://string-db.org/network/1199245.A359_00100Hypothetical protein; PFAM: Smr domain.
A359_00110 protein networkhttps://string-db.org/network/1199245.A359_00110Hypothetical protein.
A359_00120 protein networkhttps://string-db.org/network/1199245.A359_00120Hypothetical protein.
A359_00140 protein networkhttps://string-db.org/network/1199245.A359_00140Hypothetical protein.
A359_00150 protein networkhttps://string-db.org/network/1199245.A359_00150Hypothetical protein.
A359_00160 protein networkhttps://string-db.org/network/1199245.A359_00160Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
A359_00170 protein networkhttps://string-db.org/network/1199245.A359_00170Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
A359_00180 protein networkhttps://string-db.org/network/1199245.A359_00180PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family.
A359_00220 protein networkhttps://string-db.org/network/1199245.A359_00220Peroxiredoxin; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family.
A359_00240 protein networkhttps://string-db.org/network/1199245.A359_00240Phosphatidylglycerophosphatase A-like protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
thiL protein networkhttps://string-db.org/network/1199245.A359_00250Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thi [...]
nusB protein networkhttps://string-db.org/network/1199245.A359_00260NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the rib [...]
ribH protein networkhttps://string-db.org/network/1199245.A359_002706,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
A359_00280 protein networkhttps://string-db.org/network/1199245.A359_00280Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphat [...]
secF protein networkhttps://string-db.org/network/1199245.A359_00300Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) t [...]
secD protein networkhttps://string-db.org/network/1199245.A359_00310Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) t [...]
yajC protein networkhttps://string-db.org/network/1199245.A359_00320Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into mem [...]
tgt protein networkhttps://string-db.org/network/1199245.A359_00330tRNA-guanine transglycosylase, queuosine-34-forming; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon [...]
A359_00340 protein networkhttps://string-db.org/network/1199245.A359_00340Hypothetical protein.
A359_00350 protein networkhttps://string-db.org/network/1199245.A359_00350PFAM: Predicted membrane-bound metal-dependent hydrolase (DUF457).
A359_00360 protein networkhttps://string-db.org/network/1199245.A359_00360PFAM: DNA mismatch repair enzyme MutH; TIGRFAM: DNA mismatch repair endonuclease MutH.
A359_00380 protein networkhttps://string-db.org/network/1199245.A359_00380Acetyltransferase, ribosomal protein N-acetylase; PFAM: Acetyltransferase (GNAT) family.
A359_00400 protein networkhttps://string-db.org/network/1199245.A359_00400PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.
A359_00410 protein networkhttps://string-db.org/network/1199245.A359_00410Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein; PFAM: short chain dehydrogenase.
A359_00420 protein networkhttps://string-db.org/network/1199245.A359_00420Hypothetical protein.
A359_00430 protein networkhttps://string-db.org/network/1199245.A359_00430K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
pepA protein networkhttps://string-db.org/network/1199245.A359_00440Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
A359_00450 protein networkhttps://string-db.org/network/1199245.A359_00450PFAM: Predicted permease YjgP/YjgQ family.
A359_00460 protein networkhttps://string-db.org/network/1199245.A359_00460PFAM: Predicted permease YjgP/YjgQ family.
hdfR protein networkhttps://string-db.org/network/1199245.A359_00480Transcriptional regulator; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
A359_00530 protein networkhttps://string-db.org/network/1199245.A359_00530Hypothetical protein.
A359_00540 protein networkhttps://string-db.org/network/1199245.A359_00540acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the car [...]
A359_00550 protein networkhttps://string-db.org/network/1199245.A359_00550acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier [...]
A359_00570 protein networkhttps://string-db.org/network/1199245.A359_00570Phosphoenolpyruvate carboxylase, type 1.
A359_00580 protein networkhttps://string-db.org/network/1199245.A359_00580Hypothetical protein.
argE protein networkhttps://string-db.org/network/1199245.A359_00590Acetylornithine deacetylase ArgE; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase (ArgE).
argH protein networkhttps://string-db.org/network/1199245.A359_00600PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
A359_00610 protein networkhttps://string-db.org/network/1199245.A359_00610PFAM: 'Cold-shock' DNA-binding domain.
gshA protein networkhttps://string-db.org/network/1199245.A359_00620PFAM: Glutamate-cysteine ligase; TIGRFAM: glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
A359_00630 protein networkhttps://string-db.org/network/1199245.A359_00630PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; beta-phosphoglucomutase family hydrolase; haloaci [...]
A359_00650 protein networkhttps://string-db.org/network/1199245.A359_00650PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
rho protein networkhttps://string-db.org/network/1199245.A359_00660Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
A359_00670 protein networkhttps://string-db.org/network/1199245.A359_00670PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component.
A359_00680 protein networkhttps://string-db.org/network/1199245.A359_00680PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Biotin-requiring enzyme; TIGRFAM: 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component).
A359_00690 protein networkhttps://string-db.org/network/1199245.A359_00690Hypothetical protein.
A359_00700 protein networkhttps://string-db.org/network/1199245.A359_00700Hypothetical protein.
A359_00750 protein networkhttps://string-db.org/network/1199245.A359_00750PFAM: DRTGG domain; Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase.
ackA protein networkhttps://string-db.org/network/1199245.A359_00760Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
clpB protein networkhttps://string-db.org/network/1199245.A359_00770ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belong [...]
A359_00790 protein networkhttps://string-db.org/network/1199245.A359_00790Hypothetical protein.
birA protein networkhttps://string-db.org/network/1199245.A359_00800birA, biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA- [...]
murB protein networkhttps://string-db.org/network/1199245.A359_00810UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
bioD protein networkhttps://string-db.org/network/1199245.A359_00820Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an urei [...]
bioB protein networkhttps://string-db.org/network/1199245.A359_00830Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily [...]
bioA protein networkhttps://string-db.org/network/1199245.A359_00840Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-dia [...]
A359_00860 protein networkhttps://string-db.org/network/1199245.A359_00860Putative permease; PFAM: Domain of unknown function DUF20.
purL protein networkhttps://string-db.org/network/1199245.A359_00870Phosphoribosylformylglycinamidine synthase, single chain form; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of f [...]
A359_00900 protein networkhttps://string-db.org/network/1199245.A359_00900DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
dapD protein networkhttps://string-db.org/network/1199245.A359_00910PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
A359_00920 protein networkhttps://string-db.org/network/1199245.A359_00920PFAM: DHH family; DHHA1 domain; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ.
tadA protein networkhttps://string-db.org/network/1199245.A359_00950Cytosine/adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
uvrB protein networkhttps://string-db.org/network/1199245.A359_00970Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abn [...]
hda protein networkhttps://string-db.org/network/1199245.A359_00980Regulatory inactivation of DnaA Hda protein; Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of AT [...]
A359_00990 protein networkhttps://string-db.org/network/1199245.A359_00990Hypothetical protein.
rpsF protein networkhttps://string-db.org/network/1199245.A359_01000Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
priB protein networkhttps://string-db.org/network/1199245.A359_01010Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
rpsR protein networkhttps://string-db.org/network/1199245.A359_01020Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal p [...]
rplI protein networkhttps://string-db.org/network/1199245.A359_01030Ribosomal protein L9; Binds to the 23S rRNA.
A359_01040 protein networkhttps://string-db.org/network/1199245.A359_01040Hypothetical protein.
A359_01050 protein networkhttps://string-db.org/network/1199245.A359_01050Hypothetical protein.
A359_01060 protein networkhttps://string-db.org/network/1199245.A359_01060Hypothetical protein.
A359_01070 protein networkhttps://string-db.org/network/1199245.A359_01070PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: mannosyl-3-phosphoglycerate phosphatase-related protein; mannosyl-3-phosphoglycerate phosphatase family; HAD-superfamily hydrolase, subfamily [...]
A359_01080 protein networkhttps://string-db.org/network/1199245.A359_01080Hypothetical protein.
A359_01100 protein networkhttps://string-db.org/network/1199245.A359_01100Hypothetical protein.
A359_01110 protein networkhttps://string-db.org/network/1199245.A359_01110FeS assembly protein SufD; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD.
orn protein networkhttps://string-db.org/network/1199245.A359_01120Oligoribonuclease (3'->5' exoribonuclease); 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
nfo protein networkhttps://string-db.org/network/1199245.A359_01140Apurinic endonuclease APN1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deox [...]
mnmA protein networkhttps://string-db.org/network/1199245.A359_01150tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of [...]
hflD protein networkhttps://string-db.org/network/1199245.A359_01160Uncharacterized protein involved in purine metabolism; PFAM: Protein of unknown function (DUF489).
A359_01170 protein networkhttps://string-db.org/network/1199245.A359_01170PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
A359_01180 protein networkhttps://string-db.org/network/1199245.A359_01180Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain.
A359_01190 protein networkhttps://string-db.org/network/1199245.A359_01190Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain; PFAM: Transcriptional regulatory protein, C terminal.
A359_01210 protein networkhttps://string-db.org/network/1199245.A359_01210PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
A359_01230 protein networkhttps://string-db.org/network/1199245.A359_01230Sulfur relay protein, TusE/DsrC/DsvC family; Part of a sulfur-relay system.
A359_01240 protein networkhttps://string-db.org/network/1199245.A359_01240PFAM: Ribonucleotide reductase, small chain.
A359_01250 protein networkhttps://string-db.org/network/1199245.A359_01250Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [...]
ubiG protein networkhttps://string-db.org/network/1199245.A359_012603-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG [...]
gyrA protein networkhttps://string-db.org/network/1199245.A359_01270DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
topA protein networkhttps://string-db.org/network/1199245.A359_01290DNA topoisomerase I, bacterial; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one [...]
A359_01300 protein networkhttps://string-db.org/network/1199245.A359_01300PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family.
tilS protein networkhttps://string-db.org/network/1199245.A359_01310tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is [...]
A359_01320 protein networkhttps://string-db.org/network/1199245.A359_01320Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
bamD protein networkhttps://string-db.org/network/1199245.A359_01330Beta-barrel assembly machine subunit BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Consti [...]
ihfB protein networkhttps://string-db.org/network/1199245.A359_01340Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tra [...]
A359_01350 protein networkhttps://string-db.org/network/1199245.A359_01350Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
cmk protein networkhttps://string-db.org/network/1199245.A359_01360PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
serC protein networkhttps://string-db.org/network/1199245.A359_01380Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreon [...]
A359_01390 protein networkhttps://string-db.org/network/1199245.A359_01390Glycerol dehydrogenase-like oxidoreductase; PFAM: Iron-containing alcohol dehydrogenase.
A359_01400 protein networkhttps://string-db.org/network/1199245.A359_01400Hypothetical protein.
dapF protein networkhttps://string-db.org/network/1199245.A359_01410Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
A359_01420 protein networkhttps://string-db.org/network/1199245.A359_01420PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, [...]
A359_01430 protein networkhttps://string-db.org/network/1199245.A359_01430PFAM: UvrD/REP helicase; TIGRFAM: DNA helicase II.
corA protein networkhttps://string-db.org/network/1199245.A359_01440Magnesium Mg(2+) and cobalt Co(2+) transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
cysC protein networkhttps://string-db.org/network/1199245.A359_01450Adenylylsulfate kinase ApsK; Catalyzes the synthesis of activated sulfate.
cysN protein networkhttps://string-db.org/network/1199245.A359_01460Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...]
cysD protein networkhttps://string-db.org/network/1199245.A359_01470Sulfate adenylyltransferase, small subunit; PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: sulfate adenylyltransferase, small subunit.
cysG protein networkhttps://string-db.org/network/1199245.A359_01480uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. The [...]
cysH protein networkhttps://string-db.org/network/1199245.A359_01490Phosphoadenosine phosphosulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
cysI protein networkhttps://string-db.org/network/1199245.A359_01500Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities [...]
cysJ protein networkhttps://string-db.org/network/1199245.A359_01510Sulfite reductase (NADPH) flavoprotein, alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activitie [...]
A359_01520 protein networkhttps://string-db.org/network/1199245.A359_01520Queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.
queE protein networkhttps://string-db.org/network/1199245.A359_01530Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to [...]
eno protein networkhttps://string-db.org/network/1199245.A359_01540Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
pyrG protein networkhttps://string-db.org/network/1199245.A359_01550CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the fo [...]
A359_01570 protein networkhttps://string-db.org/network/1199245.A359_01570Guanosine polyphosphate synthetase/pyrophosphohydrolase; PFAM: Region found in RelA / SpoT proteins.
clsA protein networkhttps://string-db.org/network/1199245.A359_01590Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin ( [...]
ihfA protein networkhttps://string-db.org/network/1199245.A359_01600Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tr [...]
pheT protein networkhttps://string-db.org/network/1199245.A359_01610phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthe [...]
pheS protein networkhttps://string-db.org/network/1199245.A359_01620phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha s [...]
rplT protein networkhttps://string-db.org/network/1199245.A359_01630Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing function [...]
rpmI protein networkhttps://string-db.org/network/1199245.A359_01640PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
thrS protein networkhttps://string-db.org/network/1199245.A359_01660threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor en [...]
gmhA protein networkhttps://string-db.org/network/1199245.A359_01680Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
dnaQ protein networkhttps://string-db.org/network/1199245.A359_01690DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing func [...]
rnhA protein networkhttps://string-db.org/network/1199245.A359_01700Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
A359_01710 protein networkhttps://string-db.org/network/1199245.A359_01710Methylase involved in ubiquinone/menaquinone biosynthesis; PFAM: Methyltransferase domain.
gloB protein networkhttps://string-db.org/network/1199245.A359_01720Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
A359_01730 protein networkhttps://string-db.org/network/1199245.A359_01730Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
pgl protein networkhttps://string-db.org/network/1199245.A359_017403-carboxymuconate cyclase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.
argS protein networkhttps://string-db.org/network/1199245.A359_01760arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase.
A359_01770 protein networkhttps://string-db.org/network/1199245.A359_01770UDP-glucose pyrophosphorylase; PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase.
A359_01780 protein networkhttps://string-db.org/network/1199245.A359_01780Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehyd [...]
A359_01790 protein networkhttps://string-db.org/network/1199245.A359_01790PFAM: NAD dependent epimerase/dehydratase family.
rnt protein networkhttps://string-db.org/network/1199245.A359_01830Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP [...]
A359_01840 protein networkhttps://string-db.org/network/1199245.A359_01840PFAM: Glutaredoxin; TIGRFAM: monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily.
slyA protein networkhttps://string-db.org/network/1199245.A359_01850Transcriptional regulator; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.
murJ protein networkhttps://string-db.org/network/1199245.A359_01870Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
A359_01920 protein networkhttps://string-db.org/network/1199245.A359_01920Hypothetical protein.
A359_01930 protein networkhttps://string-db.org/network/1199245.A359_01930Enoyl-(acyl-carrier-protein) reductase (NADH).
rppH protein networkhttps://string-db.org/network/1199245.A359_01940NTP pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can [...]
lgt protein networkhttps://string-db.org/network/1199245.A359_01960Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
pyrF protein networkhttps://string-db.org/network/1199245.A359_01970Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamil [...]
A359_01980 protein networkhttps://string-db.org/network/1199245.A359_01980Hypothetical protein.
nfuA protein networkhttps://string-db.org/network/1199245.A359_02000IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S protein [...]
A359_02020 protein networkhttps://string-db.org/network/1199245.A359_02020Hypothetical protein.
tyrS protein networkhttps://string-db.org/network/1199245.A359_02030tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
pdxH protein networkhttps://string-db.org/network/1199245.A359_02040Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
nth protein networkhttps://string-db.org/network/1199245.A359_02060Endonuclease III, DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various dama [...]
A359_02090 protein networkhttps://string-db.org/network/1199245.A359_02090Hypothetical protein.
A359_02100 protein networkhttps://string-db.org/network/1199245.A359_02100Hypothetical protein.
asnS protein networkhttps://string-db.org/network/1199245.A359_02120PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase.
A359_02140 protein networkhttps://string-db.org/network/1199245.A359_02140Zn-dependent hydrolase, glyoxylase; PFAM: Metallo-beta-lactamase superfamily.
folE protein networkhttps://string-db.org/network/1199245.A359_02150PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
A359_02160 protein networkhttps://string-db.org/network/1199245.A359_02160Anaerobic c4-dicarboxylate membrane transporter family protein; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transport [...]
ispF protein networkhttps://string-db.org/network/1199245.A359_021702-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
ispD protein networkhttps://string-db.org/network/1199245.A359_021802-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to [...]
A359_02190 protein networkhttps://string-db.org/network/1199245.A359_02190PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
A359_02210 protein networkhttps://string-db.org/network/1199245.A359_02210PFAM: Serine acetyltransferase, N-terminal; Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; Belongs to the transferase hexapeptide repeat family.
gpsA protein networkhttps://string-db.org/network/1199245.A359_02220PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase fam [...]
secB protein networkhttps://string-db.org/network/1199245.A359_02230Protein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor protein [...]
A359_02240 protein networkhttps://string-db.org/network/1199245.A359_02240Hypothetical protein.
A359_02260 protein networkhttps://string-db.org/network/1199245.A359_02260Rhodanese-related sulfurtransferase; PFAM: Rhodanese-like domain.
ribA protein networkhttps://string-db.org/network/1199245.A359_02300GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
A359_02330 protein networkhttps://string-db.org/network/1199245.A359_023306-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
A359_02340 protein networkhttps://string-db.org/network/1199245.A359_02340Hypothetical protein.
A359_02350 protein networkhttps://string-db.org/network/1199245.A359_02350PFAM: NAD dependent epimerase/dehydratase family.
A359_02360 protein networkhttps://string-db.org/network/1199245.A359_02360PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type; signal peptide peptidase SppA, 67K type.
A359_02380 protein networkhttps://string-db.org/network/1199245.A359_02380Mismatch repair ATPase (MutS family); PFAM: MutS domain V.
A359_02390 protein networkhttps://string-db.org/network/1199245.A359_02390Mismatch repair ATPase (MutS family); PFAM: MutS domain V.
purT protein networkhttps://string-db.org/network/1199245.A359_02410Formate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-p [...]
A359_02420 protein networkhttps://string-db.org/network/1199245.A359_02420Hypothetical protein.
A359_02430 protein networkhttps://string-db.org/network/1199245.A359_02430Hypothetical protein.
glyS protein networkhttps://string-db.org/network/1199245.A359_02440PFAM: Glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, beta subunit.
glyQ protein networkhttps://string-db.org/network/1199245.A359_02450PFAM: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, alpha subunit.
A359_02460 protein networkhttps://string-db.org/network/1199245.A359_02460Hypothetical protein; PFAM: Endonuclease/Exonuclease/phosphatase family.
gpmA protein networkhttps://string-db.org/network/1199245.A359_02480Phosphoglycerate mutase, BPG-dependent, family 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM s [...]
rplY protein networkhttps://string-db.org/network/1199245.A359_02500Ribosomal protein L25 (general stress protein Ctc); This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial [...]
ddl protein networkhttps://string-db.org/network/1199245.A359_02510D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
kdsA protein networkhttps://string-db.org/network/1199245.A359_02530PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family.
A359_02540 protein networkhttps://string-db.org/network/1199245.A359_02540Hypothetical protein.
prmC protein networkhttps://string-db.org/network/1199245.A359_02550protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally [...]
prfA protein networkhttps://string-db.org/network/1199245.A359_02560Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
A359_02570 protein networkhttps://string-db.org/network/1199245.A359_02570PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit.
ribB protein networkhttps://string-db.org/network/1199245.A359_025803,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
A359_02590 protein networkhttps://string-db.org/network/1199245.A359_02590PFAM: Protein of unknown function (DUF526).
hldE protein networkhttps://string-db.org/network/1199245.A359_02600D-heptose-7- phosphate 1-kinase,D-heptose-1-phosphate adenylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- [...]
A359_02610 protein networkhttps://string-db.org/network/1199245.A359_02610Hypothetical protein.
cca protein networkhttps://string-db.org/network/1199245.A359_02620tRNA nucleotidyltransferase/poly(A) polymerase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucle [...]
A359_02630 protein networkhttps://string-db.org/network/1199245.A359_02630PFAM: Haemolysin expression modulating protein.
A359_02650 protein networkhttps://string-db.org/network/1199245.A359_02650GTP-binding protein TypA/BipA; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-bind [...]
coaA protein networkhttps://string-db.org/network/1199245.A359_02660PFAM: Phosphoribulokinase / Uridine kinase family; TIGRFAM: pantothenate kinase, bacterial type.
A359_02670 protein networkhttps://string-db.org/network/1199245.A359_02670Hypothetical protein.
secE protein networkhttps://string-db.org/network/1199245.A359_02730Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; B [...]
nusG protein networkhttps://string-db.org/network/1199245.A359_02740Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the [...]
rplK protein networkhttps://string-db.org/network/1199245.A359_0275050S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
rplA protein networkhttps://string-db.org/network/1199245.A359_02760Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplJ protein networkhttps://string-db.org/network/1199245.A359_02770Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein [...]
rplL protein networkhttps://string-db.org/network/1199245.A359_02780Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacter [...]
rpoB protein networkhttps://string-db.org/network/1199245.A359_02790DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoC protein networkhttps://string-db.org/network/1199245.A359_02800DNA-directed RNA polymerase, beta'' subunit, predominant form; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
A359_02810 protein networkhttps://string-db.org/network/1199245.A359_02810Hypothetical protein.
mrdA protein networkhttps://string-db.org/network/1199245.A359_02820Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
mrdB protein networkhttps://string-db.org/network/1199245.A359_02830Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
A359_02840 protein networkhttps://string-db.org/network/1199245.A359_02840PFAM: Protein of unknown function (DUF493); Belongs to the UPF0250 family.
lipB protein networkhttps://string-db.org/network/1199245.A359_02850Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can al [...]
lipA protein networkhttps://string-db.org/network/1199245.A359_02860Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, ther [...]
panC protein networkhttps://string-db.org/network/1199245.A359_02880Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase f [...]
panB protein networkhttps://string-db.org/network/1199245.A359_028903-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to [...]
A359_02900 protein networkhttps://string-db.org/network/1199245.A359_02900PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.
pcnB protein networkhttps://string-db.org/network/1199245.A359_02910poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencin [...]
dksA protein networkhttps://string-db.org/network/1199245.A359_02920Transcriptional regulator, TraR/DksA family; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regu [...]
A359_02930 protein networkhttps://string-db.org/network/1199245.A359_02930Hypothetical protein.
A359_02940 protein networkhttps://string-db.org/network/1199245.A359_02940Hypothetical protein.
purM protein networkhttps://string-db.org/network/1199245.A359_02960Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synth [...]
epmA protein networkhttps://string-db.org/network/1199245.A359_02970lysyl-tRNA synthetase-like protein GenX; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dep [...]
A359_02980 protein networkhttps://string-db.org/network/1199245.A359_02980PFAM: Mechanosensitive ion channel.
psd protein networkhttps://string-db.org/network/1199245.A359_02990Phosphatidylserine decarboxylase precursor; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
A359_03000 protein networkhttps://string-db.org/network/1199245.A359_03000SufE protein probably involved in Fe-S center assembly; PFAM: Fe-S metabolism associated domain.
A359_03010 protein networkhttps://string-db.org/network/1199245.A359_03010Cysteine desulfurase-like protein, SufS subfamily; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a varie [...]
A359_03020 protein networkhttps://string-db.org/network/1199245.A359_03020ABC-type transport system involved in Fe-S cluster assembly, permease component; PFAM: Uncharacterized protein family (UPF0051).
A359_03030 protein networkhttps://string-db.org/network/1199245.A359_03030PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC.
A359_03040 protein networkhttps://string-db.org/network/1199245.A359_03040FeS assembly protein SufB; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB.
A359_03050 protein networkhttps://string-db.org/network/1199245.A359_03050PFAM: Iron-sulphur cluster biosynthesis; TIGRFAM: FeS assembly scaffold SufA; Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
A359_03060 protein networkhttps://string-db.org/network/1199245.A359_03060Phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III [...]
A359_03070 protein networkhttps://string-db.org/network/1199245.A359_03070Hypothetical protein.
rplQ protein networkhttps://string-db.org/network/1199245.A359_03080PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17.
rpoA protein networkhttps://string-db.org/network/1199245.A359_03090DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpsD protein networkhttps://string-db.org/network/1199245.A359_03100Ribosomal protein S4, bacterial/organelle type; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpsK protein networkhttps://string-db.org/network/1199245.A359_0311030S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
A359_03120 protein networkhttps://string-db.org/network/1199245.A359_03120PFAM: Ribosomal protein S13/S18; TIGRFAM: 30S ribosomal protein S13.
rpmJ protein networkhttps://string-db.org/network/1199245.A359_03140PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type; Belongs to the bacterial ribosomal protein bL36 family.
secY protein networkhttps://string-db.org/network/1199245.A359_03150Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral [...]
rplO protein networkhttps://string-db.org/network/1199245.A359_03160Ribosomal protein L15, bacterial/organelle; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
rpmD protein networkhttps://string-db.org/network/1199245.A359_03170PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle.
rpsE protein networkhttps://string-db.org/network/1199245.A359_03180Ribosomal protein S5, bacterial/organelle type; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal rib [...]
rplR protein networkhttps://string-db.org/network/1199245.A359_03190Ribosomal protein L18, bacterial type; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the centr [...]
rplF protein networkhttps://string-db.org/network/1199245.A359_03200Ribosomal protein L6, bacterial type; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, an [...]
rpsH protein networkhttps://string-db.org/network/1199245.A359_03210Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the [...]
rpsN protein networkhttps://string-db.org/network/1199245.A359_03220Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the univer [...]
rplE protein networkhttps://string-db.org/network/1199245.A359_03230Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In [...]
rplX protein networkhttps://string-db.org/network/1199245.A359_03240Ribosomal protein L24, bacterial/organelle; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplN protein networkhttps://string-db.org/network/1199245.A359_03250Ribosomal protein L14, bacterial/organelle; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rpsQ protein networkhttps://string-db.org/network/1199245.A359_0326030S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rpmC protein networkhttps://string-db.org/network/1199245.A359_03270PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
rplP protein networkhttps://string-db.org/network/1199245.A359_03280Ribosomal protein L16, bacterial/organelle; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsC protein networkhttps://string-db.org/network/1199245.A359_03290Ribosomal protein S3, bacterial type; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 [...]
rplV protein networkhttps://string-db.org/network/1199245.A359_03300Ribosomal protein L22, bacterial type; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that l [...]
rpsS protein networkhttps://string-db.org/network/1199245.A359_03310Ribosomal protein S19, bacterial/organelle; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplB protein networkhttps://string-db.org/network/1199245.A359_03320Ribosomal protein L2, bacterial/organellar; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide b [...]
rplW protein networkhttps://string-db.org/network/1199245.A359_03330Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking [...]
rplD protein networkhttps://string-db.org/network/1199245.A359_0334050S ribosomal protein L4, bacterial/organelle; Forms part of the polypeptide exit tunnel.
rplC protein networkhttps://string-db.org/network/1199245.A359_0335050S ribosomal protein L3, bacterial; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rpsJ protein networkhttps://string-db.org/network/1199245.A359_03360Ribosomal protein S10, bacterial/organelle; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
A359_03370 protein networkhttps://string-db.org/network/1199245.A359_03370Hypothetical protein.
A359_03390 protein networkhttps://string-db.org/network/1199245.A359_03390PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
proS protein networkhttps://string-db.org/network/1199245.A359_03400prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
nadE protein networkhttps://string-db.org/network/1199245.A359_03420NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
zapD protein networkhttps://string-db.org/network/1199245.A359_03430Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
coaE protein networkhttps://string-db.org/network/1199245.A359_03440dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
A359_03450 protein networkhttps://string-db.org/network/1199245.A359_03450Hypothetical protein.
A359_03460 protein networkhttps://string-db.org/network/1199245.A359_03460PFAM: IMP dehydrogenase / GMP reductase domain.
A359_03470 protein networkhttps://string-db.org/network/1199245.A359_03470Hypothetical protein.
secA protein networkhttps://string-db.org/network/1199245.A359_03480Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to [...]
A359_03490 protein networkhttps://string-db.org/network/1199245.A359_03490Hypothetical protein.
A359_03500 protein networkhttps://string-db.org/network/1199245.A359_03500PFAM: Protein of unknown function (DUF721).
lpxC protein networkhttps://string-db.org/network/1199245.A359_03510UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed st [...]
ftsZ protein networkhttps://string-db.org/network/1199245.A359_03520Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
ftsA protein networkhttps://string-db.org/network/1199245.A359_03530Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
A359_03540 protein networkhttps://string-db.org/network/1199245.A359_03540Hypothetical protein.
murC protein networkhttps://string-db.org/network/1199245.A359_03550UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
murG protein networkhttps://string-db.org/network/1199245.A359_03560Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
murD protein networkhttps://string-db.org/network/1199245.A359_03570UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF [...]
mraY protein networkhttps://string-db.org/network/1199245.A359_03580Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...]
murF protein networkhttps://string-db.org/network/1199245.A359_03590UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of mure [...]
murE protein networkhttps://string-db.org/network/1199245.A359_03600UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial ce [...]
A359_03610 protein networkhttps://string-db.org/network/1199245.A359_03610Cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain.
rsmH protein networkhttps://string-db.org/network/1199245.A359_03620S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
recD protein networkhttps://string-db.org/network/1199245.A359_03650DNA helicase/exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and proce [...]
A359_03670 protein networkhttps://string-db.org/network/1199245.A359_03670PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
uvrC protein networkhttps://string-db.org/network/1199245.A359_03680Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsib [...]
cysA protein networkhttps://string-db.org/network/1199245.A359_03730Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
A359_03740 protein networkhttps://string-db.org/network/1199245.A359_03740Sulfate ABC transporter, permease protein CysW; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: sulfate ABC transporter, permease protein CysW; sulfate ABC tra [...]
A359_03750 protein networkhttps://string-db.org/network/1199245.A359_03750Sulfate ABC transporter, permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport syste [...]
A359_03760 protein networkhttps://string-db.org/network/1199245.A359_03760PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: sulfate/thiosulfate-binding protein.
A359_03770 protein networkhttps://string-db.org/network/1199245.A359_03770Hypothetical protein.
A359_03780 protein networkhttps://string-db.org/network/1199245.A359_03780Hypothetical protein.
A359_03790 protein networkhttps://string-db.org/network/1199245.A359_03790Membrane protein TerC, possibly involved in tellurium resistance; PFAM: CBS domain; Integral membrane protein TerC family; Transporter associated domain.
A359_03800 protein networkhttps://string-db.org/network/1199245.A359_03800PFAM: PTS system fructose IIA component; PTS system sorbose subfamily IIB component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component; PTS system, mannose/fructose/sorbose fami [...]
A359_03810 protein networkhttps://string-db.org/network/1199245.A359_03810PFAM: PTS system sorbose-specific iic component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC component.
A359_03820 protein networkhttps://string-db.org/network/1199245.A359_03820PFAM: PTS system mannose/fructose/sorbose family IID component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IID component.
A359_03830 protein networkhttps://string-db.org/network/1199245.A359_03830Hypothetical protein.
A359_03840 protein networkhttps://string-db.org/network/1199245.A359_03840Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
A359_03850 protein networkhttps://string-db.org/network/1199245.A359_03850Putative membrane-associated protein; PFAM: SNARE associated Golgi protein.
A359_03860 protein networkhttps://string-db.org/network/1199245.A359_03860Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
tal protein networkhttps://string-db.org/network/1199245.A359_03870Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
A359_03880 protein networkhttps://string-db.org/network/1199245.A359_03880Hypothetical protein; PFAM: Uncharacterized BCR, YaiI/YqxD family COG1671; Belongs to the UPF0178 family.
A359_03890 protein networkhttps://string-db.org/network/1199245.A359_03890PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ.
A359_03900 protein networkhttps://string-db.org/network/1199245.A359_03900PFAM: 'Cold-shock' DNA-binding domain.
A359_03920 protein networkhttps://string-db.org/network/1199245.A359_03920Hypothetical protein.
A359_03930 protein networkhttps://string-db.org/network/1199245.A359_03930Hypothetical protein.
mtnN protein networkhttps://string-db.org/network/1199245.A359_039505''-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy [...]
A359_03960 protein networkhttps://string-db.org/network/1199245.A359_03960Hypothetical protein.
metK protein networkhttps://string-db.org/network/1199245.A359_03980Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet format [...]
A359_03990 protein networkhttps://string-db.org/network/1199245.A359_03990Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
pyrD protein networkhttps://string-db.org/network/1199245.A359_04000Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
A359_04020 protein networkhttps://string-db.org/network/1199245.A359_04020Folate-binding protein YgfZ; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act [...]
A359_04040 protein networkhttps://string-db.org/network/1199245.A359_04040DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain.
A359_04050 protein networkhttps://string-db.org/network/1199245.A359_04050Hypothetical protein.
A359_04060 protein networkhttps://string-db.org/network/1199245.A359_04060Hypothetical protein.
tuf protein networkhttps://string-db.org/network/1199245.A359_04070Translation elongation factor TU; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
fusA protein networkhttps://string-db.org/network/1199245.A359_04080Translation elongation factor EF-G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PR [...]
rpsG protein networkhttps://string-db.org/network/1199245.A359_04090Ribosomal protein S7, bacterial/organelle; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at [...]
rpsL protein networkhttps://string-db.org/network/1199245.A359_04100Ribosomal protein S12, bacterial/organelle; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interf [...]
tusB protein networkhttps://string-db.org/network/1199245.A359_04110Sulfur relay protein TusB/DsrH; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
tusC protein networkhttps://string-db.org/network/1199245.A359_04120Sulfur relay protein TusC/DsrF; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
tusD protein networkhttps://string-db.org/network/1199245.A359_04130Sulfur relay protein TusD/DsrE; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and [...]
ung protein networkhttps://string-db.org/network/1199245.A359_04140Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
grpE protein networkhttps://string-db.org/network/1199245.A359_04150Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with [...]
nadK protein networkhttps://string-db.org/network/1199245.A359_04160Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-h [...]
A359_04170 protein networkhttps://string-db.org/network/1199245.A359_04170uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
hemC protein networkhttps://string-db.org/network/1199245.A359_04180Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
A359_04190 protein networkhttps://string-db.org/network/1199245.A359_04190Hypothetical protein.
A359_04200 protein networkhttps://string-db.org/network/1199245.A359_04200PFAM: Adenylate cyclase, class-I; Belongs to the adenylyl cyclase class-1 family.
A359_04220 protein networkhttps://string-db.org/network/1199245.A359_04220Potassium uptake protein, TrkH family; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.
A359_04230 protein networkhttps://string-db.org/network/1199245.A359_04230Glycosyltransferase; PFAM: Glycosyl transferases group 1.
A359_04240 protein networkhttps://string-db.org/network/1199245.A359_042403-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV( [...]
A359_04250 protein networkhttps://string-db.org/network/1199245.A359_04250PFAM: Glycosyl transferase family 2.
coaD protein networkhttps://string-db.org/network/1199245.A359_04260Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial Co [...]
rpmG protein networkhttps://string-db.org/network/1199245.A359_04270PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/1199245.A359_04280PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
rpiA protein networkhttps://string-db.org/network/1199245.A359_04290Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
A359_04300 protein networkhttps://string-db.org/network/1199245.A359_04300Hypothetical protein.
fabA protein networkhttps://string-db.org/network/1199245.A359_04310Beta-hydroxyacyl-(acyl carrier protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-de [...]
A359_04320 protein networkhttps://string-db.org/network/1199245.A359_04320Putative ATP-dependent protease; PFAM: Lon protease (S16) C-terminal proteolytic domain.
serS protein networkhttps://string-db.org/network/1199245.A359_04340seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
tsaC protein networkhttps://string-db.org/network/1199245.A359_04350Putative translation factor (SUA5); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the c [...]
A359_04360 protein networkhttps://string-db.org/network/1199245.A359_04360Hypothetical protein.
rnb protein networkhttps://string-db.org/network/1199245.A359_04370Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
A359_04380 protein networkhttps://string-db.org/network/1199245.A359_04380PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin, GrxA family.
A359_04390 protein networkhttps://string-db.org/network/1199245.A359_04390RNA methyltransferase, RsmD family; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
A359_04400 protein networkhttps://string-db.org/network/1199245.A359_04400PFAM: MarC family integral membrane protein; TIGRFAM: membrane protein, MarC family.
asd protein networkhttps://string-db.org/network/1199245.A359_04410Aspartate-semialdehyde dehydrogenase, gamma-proteobacterial; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosp [...]
A359_04420 protein networkhttps://string-db.org/network/1199245.A359_04420Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
rplU protein networkhttps://string-db.org/network/1199245.A359_04430Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
rpmA protein networkhttps://string-db.org/network/1199245.A359_04440PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
A359_04450 protein networkhttps://string-db.org/network/1199245.A359_04450Hypothetical protein.
obg protein networkhttps://string-db.org/network/1199245.A359_04460Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a ro [...]
prfC protein networkhttps://string-db.org/network/1199245.A359_04470Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for U [...]
A359_04480 protein networkhttps://string-db.org/network/1199245.A359_04480Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.
A359_04490 protein networkhttps://string-db.org/network/1199245.A359_04490DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonu [...]
tusA protein networkhttps://string-db.org/network/1199245.A359_04510Putative redox protein, regulator of disulfide bond formation; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during sy [...]
A359_04520 protein networkhttps://string-db.org/network/1199245.A359_04520Hypothetical protein.
A359_04530 protein networkhttps://string-db.org/network/1199245.A359_04530Glycosyltransferase; PFAM: Glycosyl transferases group 1.
A359_04540 protein networkhttps://string-db.org/network/1199245.A359_04540PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs [...]
ychF protein networkhttps://string-db.org/network/1199245.A359_04580GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
pth protein networkhttps://string-db.org/network/1199245.A359_04590peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
prs protein networkhttps://string-db.org/network/1199245.A359_04600Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
ispE protein networkhttps://string-db.org/network/1199245.A359_046104-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. I [...]
lolB protein networkhttps://string-db.org/network/1199245.A359_04620Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
A359_04630 protein networkhttps://string-db.org/network/1199245.A359_04630Hypothetical protein.
A359_04640 protein networkhttps://string-db.org/network/1199245.A359_04640Hypothetical protein.
A359_04650 protein networkhttps://string-db.org/network/1199245.A359_04650PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain; TIGRFAM: TonB-dependent copper receptor.
purH protein networkhttps://string-db.org/network/1199245.A359_04670PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.
purD protein networkhttps://string-db.org/network/1199245.A359_04680Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C doma [...]
queA protein networkhttps://string-db.org/network/1199245.A359_04710S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ [...]
efp protein networkhttps://string-db.org/network/1199245.A359_04730Translation elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, [...]
A359_04740 protein networkhttps://string-db.org/network/1199245.A359_04740PFAM: Radical SAM superfamily; TIGRFAM: KamA family protein; lysine-2,3-aminomutase-related protein.
A359_04750 protein networkhttps://string-db.org/network/1199245.A359_04750ATPase, YjeE family; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family.
A359_04760 protein networkhttps://string-db.org/network/1199245.A359_04760Hypothetical protein.
A359_04770 protein networkhttps://string-db.org/network/1199245.A359_04770Hypothetical protein.
A359_04780 protein networkhttps://string-db.org/network/1199245.A359_04780Hypothetical protein.
miaA protein networkhttps://string-db.org/network/1199245.A359_04790tRNA isopentenyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6- [...]
hfq protein networkhttps://string-db.org/network/1199245.A359_04800RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in [...]
A359_04820 protein networkhttps://string-db.org/network/1199245.A359_04820HflK protein; HflC and HflK could encode or regulate a protease.
A359_04830 protein networkhttps://string-db.org/network/1199245.A359_04830HflC protein; HflC and HflK could regulate a protease.
purA protein networkhttps://string-db.org/network/1199245.A359_04840Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
rnr protein networkhttps://string-db.org/network/1199245.A359_04850Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily.
rlmB protein networkhttps://string-db.org/network/1199245.A359_04860rRNA methylase, putative, group 3; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase [...]
greA protein networkhttps://string-db.org/network/1199245.A359_04880Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
A359_04890 protein networkhttps://string-db.org/network/1199245.A359_0489023S rRNA methylase; PFAM: FtsJ-like methyltransferase; TIGRFAM: cell division protein FtsJ.
ftsH protein networkhttps://string-db.org/network/1199245.A359_04900ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane [...]
A359_04910 protein networkhttps://string-db.org/network/1199245.A359_04910Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate [...]
glmM protein networkhttps://string-db.org/network/1199245.A359_04920Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
A359_04930 protein networkhttps://string-db.org/network/1199245.A359_04930Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
nusA protein networkhttps://string-db.org/network/1199245.A359_04950Transcription termination factor NusA; Participates in both transcription termination and antitermination.
infB protein networkhttps://string-db.org/network/1199245.A359_04960Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
rbfA protein networkhttps://string-db.org/network/1199245.A359_04970Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
truB protein networkhttps://string-db.org/network/1199245.A359_04980tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
A359_04990 protein networkhttps://string-db.org/network/1199245.A359_04990PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain.
A359_05000 protein networkhttps://string-db.org/network/1199245.A359_05000PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
lolA protein networkhttps://string-db.org/network/1199245.A359_05010Periplasmic chaperone LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-ter [...]
pyrI protein networkhttps://string-db.org/network/1199245.A359_05020Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
pyrB protein networkhttps://string-db.org/network/1199245.A359_05030PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; Belongs to t [...]
msbA protein networkhttps://string-db.org/network/1199245.A359_05040Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) [...]
lpxK protein networkhttps://string-db.org/network/1199245.A359_05050lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-pho [...]
A359_05060 protein networkhttps://string-db.org/network/1199245.A359_05060PFAM: Trm112p-like protein; Belongs to the UPF0434 family.
kdsB protein networkhttps://string-db.org/network/1199245.A359_050703-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
ligA protein networkhttps://string-db.org/network/1199245.A359_05080DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as t [...]
zipA protein networkhttps://string-db.org/network/1199245.A359_05090Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also req [...]
hspQ protein networkhttps://string-db.org/network/1199245.A359_05100Hemimethylated DNA binding domain protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.
A359_05110 protein networkhttps://string-db.org/network/1199245.A359_05110Putative periplasmic or secreted lipoprotein; PFAM: Putative phospholipid-binding domain.
nadD protein networkhttps://string-db.org/network/1199245.A359_05120Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
A359_05130 protein networkhttps://string-db.org/network/1199245.A359_05130PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
lptE protein networkhttps://string-db.org/network/1199245.A359_05140Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may s [...]
leuS protein networkhttps://string-db.org/network/1199245.A359_05150PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; Belongs to the class-I aminoacyl-tRNA synthetase f [...]
A359_05160 protein networkhttps://string-db.org/network/1199245.A359_05160Hemagglutinin-like protein; PFAM: Hep_Hag; YadA-like C-terminal region.
rpsO protein networkhttps://string-db.org/network/1199245.A359_05170Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
pnp protein networkhttps://string-db.org/network/1199245.A359_05180Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
deaD protein networkhttps://string-db.org/network/1199245.A359_05190DNA/RNA helicase, superfamily II; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
A359_05200 protein networkhttps://string-db.org/network/1199245.A359_05200Hypothetical protein.
pyrE protein networkhttps://string-db.org/network/1199245.A359_05210Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
dut protein networkhttps://string-db.org/network/1199245.A359_05230Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the int [...]
A359_05240 protein networkhttps://string-db.org/network/1199245.A359_05240Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantot [...]
A359_05280 protein networkhttps://string-db.org/network/1199245.A359_05280PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase family M24.
A359_05290 protein networkhttps://string-db.org/network/1199245.A359_05290PFAM: FAD binding domain; TIGRFAM: 2-polyprenyl-6-methoxyphenol 4-hydroxylase; Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family.
A359_05300 protein networkhttps://string-db.org/network/1199245.A359_05300PFAM: FAD binding domain; TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family.
A359_05320 protein networkhttps://string-db.org/network/1199245.A359_05320PFAM: Exonuclease; Exonuclease C-terminal.
A359_05340 protein networkhttps://string-db.org/network/1199245.A359_05340Metalloendopeptidase-like membrane protein; PFAM: Peptidase family M23.
rpsT protein networkhttps://string-db.org/network/1199245.A359_05360Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
dnaJ protein networkhttps://string-db.org/network/1199245.A359_05370Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an [...]
dnaK protein networkhttps://string-db.org/network/1199245.A359_05380Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
glyA protein networkhttps://string-db.org/network/1199245.A359_05390Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the [...]
A359_05410 protein networkhttps://string-db.org/network/1199245.A359_05410PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family.
ileS protein networkhttps://string-db.org/network/1199245.A359_05420Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
lspA protein networkhttps://string-db.org/network/1199245.A359_05430Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
A359_05440 protein networkhttps://string-db.org/network/1199245.A359_05440Hypothetical protein.
ispH protein networkhttps://string-db.org/network/1199245.A359_05450(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and d [...]
A359_05460 protein networkhttps://string-db.org/network/1199245.A359_05460Hypothetical protein.
djlA protein networkhttps://string-db.org/network/1199245.A359_05470Protein with DnaJ-like domain; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic ac [...]
lptD protein networkhttps://string-db.org/network/1199245.A359_05480Organic solvent tolerance protein OstA; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
surA protein networkhttps://string-db.org/network/1199245.A359_05490Parvulin-like peptidyl-prolyl isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation o [...]
pdxA protein networkhttps://string-db.org/network/1199245.A359_055004-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decar [...]
rsmA protein networkhttps://string-db.org/network/1199245.A359_05510Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
A359_05520 protein networkhttps://string-db.org/network/1199245.A359_05520Hypothetical protein.
apaH protein networkhttps://string-db.org/network/1199245.A359_05530Symmetrical bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
A359_05540 protein networkhttps://string-db.org/network/1199245.A359_05540Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
carB protein networkhttps://string-db.org/network/1199245.A359_05550Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; C [...]
carA protein networkhttps://string-db.org/network/1199245.A359_05560PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
dapB protein networkhttps://string-db.org/network/1199245.A359_05570Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
A359_05590 protein networkhttps://string-db.org/network/1199245.A359_05590Phosphate/sulfate permease; PFAM: Phosphate transporter family.
pgi protein networkhttps://string-db.org/network/1199245.A359_05610PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
A359_05620 protein networkhttps://string-db.org/network/1199245.A359_05620Hypothetical protein.
aspS protein networkhttps://string-db.org/network/1199245.A359_05630aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
A359_05640 protein networkhttps://string-db.org/network/1199245.A359_05640Pyruvate dehydrogenase E1 component, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
A359_05650 protein networkhttps://string-db.org/network/1199245.A359_05650PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long for [...]
A359_05660 protein networkhttps://string-db.org/network/1199245.A359_05660Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
A359_05670 protein networkhttps://string-db.org/network/1199245.A359_05670Molecular chaperone (small heat shock protein); PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family.
A359_05690 protein networkhttps://string-db.org/network/1199245.A359_05690Hypothetical protein.
A359_05700 protein networkhttps://string-db.org/network/1199245.A359_05700PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
A359_05710 protein networkhttps://string-db.org/network/1199245.A359_05710Fe2+/Zn2+ uptake regulation protein; PFAM: Ferric uptake regulator family; Belongs to the Fur family.
A359_05720 protein networkhttps://string-db.org/network/1199245.A359_05720Hypothetical protein.
A359_05730 protein networkhttps://string-db.org/network/1199245.A359_05730PFAM: Uncharacterised protein family (UPF0259).
ybeY protein networkhttps://string-db.org/network/1199245.A359_05740Metalloprotein, YbeY/UPF0054 family; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
A359_05750 protein networkhttps://string-db.org/network/1199245.A359_05750Hypothetical protein.
A359_05760 protein networkhttps://string-db.org/network/1199245.A359_05760Hypothetical protein.
lnt protein networkhttps://string-db.org/network/1199245.A359_05770Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrol [...]
nuoN protein networkhttps://string-db.org/network/1199245.A359_05800Proton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron [...]
A359_05810 protein networkhttps://string-db.org/network/1199245.A359_05810PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.
A359_05820 protein networkhttps://string-db.org/network/1199245.A359_05820Proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM [...]
nuoK protein networkhttps://string-db.org/network/1199245.A359_05830NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron [...]
A359_05840 protein networkhttps://string-db.org/network/1199245.A359_05840NADH:ubiquinone oxidoreductase subunit 6 (chain J); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to [...]
nuoI protein networkhttps://string-db.org/network/1199245.A359_05850NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enz [...]
nuoH protein networkhttps://string-db.org/network/1199245.A359_05860NADH:ubiquinone oxidoreductase subunit 1 (chain H); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron accept [...]
A359_05870 protein networkhttps://string-db.org/network/1199245.A359_05870NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton transl [...]
A359_05880 protein networkhttps://string-db.org/network/1199245.A359_05880NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit f [...]
A359_05890 protein networkhttps://string-db.org/network/1199245.A359_05890PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit.
nuoC protein networkhttps://string-db.org/network/1199245.A359_05900NADH/F420H2 dehydrogenase, subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enz [...]
nuoB protein networkhttps://string-db.org/network/1199245.A359_05910NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the e [...]
nuoA protein networkhttps://string-db.org/network/1199245.A359_05920NADH:ubiquinone oxidoreductase subunit 3 (chain A); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron accept [...]
A359_05930 protein networkhttps://string-db.org/network/1199245.A359_05930Hypothetical protein.
hslU protein networkhttps://string-db.org/network/1199245.A359_05940ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by Hsl [...]
hslV protein networkhttps://string-db.org/network/1199245.A359_05950ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
A359_05960 protein networkhttps://string-db.org/network/1199245.A359_05960Hypothetical protein.
engB protein networkhttps://string-db.org/network/1199245.A359_05970Ribosome biogenesis GTP-binding protein YsxC/EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPas [...]
infA protein networkhttps://string-db.org/network/1199245.A359_05980Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
A359_05990 protein networkhttps://string-db.org/network/1199245.A359_05990Arabinose efflux permease family protein; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily.
glnS protein networkhttps://string-db.org/network/1199245.A359_06000PFAM: tRNA synthetases class I (E and Q), catalytic domain; tRNA synthetases class I (E and Q), anti-codon binding domain; TIGRFAM: glutaminyl-tRNA synthetase.
A359_06060 protein networkhttps://string-db.org/network/1199245.A359_06060PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; Belongs to the GST superfamily.
A359_06070 protein networkhttps://string-db.org/network/1199245.A359_06070PFAM: Stringent starvation protein B.
groL protein networkhttps://string-db.org/network/1199245.A359_06090Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
groS protein networkhttps://string-db.org/network/1199245.A359_06100Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
A359_06110 protein networkhttps://string-db.org/network/1199245.A359_06110Flavodoxin, long chain; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
A359_06120 protein networkhttps://string-db.org/network/1199245.A359_06120Hypothetical protein.
accD protein networkhttps://string-db.org/network/1199245.A359_06130acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carr [...]
A359_06140 protein networkhttps://string-db.org/network/1199245.A359_06140Folylpolyglutamate synthase/dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroat [...]
A359_06150 protein networkhttps://string-db.org/network/1199245.A359_06150Putative membrane protein, required for colicin V production; PFAM: Colicin V production protein.
purF protein networkhttps://string-db.org/network/1199245.A359_06160Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine p [...]
ubiX protein networkhttps://string-db.org/network/1199245.A359_06170Polyprenyl p-hydroxybenzoate/phenylacrylic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic [...]
htpG protein networkhttps://string-db.org/network/1199245.A359_06180Molecular chaperone of HSP90 family; Molecular chaperone. Has ATPase activity.
adk protein networkhttps://string-db.org/network/1199245.A359_06190Adenylate kinase family protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucle [...]
A359_06210 protein networkhttps://string-db.org/network/1199245.A359_06210DNA polymerase III, subunit gamma/tau; PFAM: ATPase family associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; DNA polymerase III tau subunit [...]
A359_06220 protein networkhttps://string-db.org/network/1199245.A359_06220PFAM: Primosomal replication protein priB and priC.
A359_06230 protein networkhttps://string-db.org/network/1199245.A359_06230Hypothetical protein.
folD protein networkhttps://string-db.org/network/1199245.A359_062505,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hyd [...]
cysS protein networkhttps://string-db.org/network/1199245.A359_06260PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
lpxH protein networkhttps://string-db.org/network/1199245.A359_06270UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water [...]
A359_06280 protein networkhttps://string-db.org/network/1199245.A359_06280Hypothetical protein.
purE protein networkhttps://string-db.org/network/1199245.A359_06290Phosphoribosylaminoimidazole carboxylase, PurE protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
purK protein networkhttps://string-db.org/network/1199245.A359_06300Phosphoribosylaminoimidazole carboxylase, PurK protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5- [...]
A359_06310 protein networkhttps://string-db.org/network/1199245.A359_06310PFAM: FAD binding domain; TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family.
tolQ protein networkhttps://string-db.org/network/1199245.A359_06320TolQ protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, fo [...]
A359_06330 protein networkhttps://string-db.org/network/1199245.A359_06330PFAM: Biopolymer transport protein ExbD/TolR; TIGRFAM: TolR protein.
A359_06340 protein networkhttps://string-db.org/network/1199245.A359_06340Membrane protein involved in colicin uptake; PFAM: TolA C-terminal; TIGRFAM: TolA protein.
tolB protein networkhttps://string-db.org/network/1199245.A359_06350Tol-pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membra [...]
pal protein networkhttps://string-db.org/network/1199245.A359_06360Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
cpoB protein networkhttps://string-db.org/network/1199245.A359_06370Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
rpoD protein networkhttps://string-db.org/network/1199245.A359_06390RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma fac [...]
dnaG protein networkhttps://string-db.org/network/1199245.A359_06400DNA primase, catalytic core; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpsU protein networkhttps://string-db.org/network/1199245.A359_06410PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
atpC protein networkhttps://string-db.org/network/1199245.A359_06420ATP synthase, F1 epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
atpD protein networkhttps://string-db.org/network/1199245.A359_06430ATP synthase, F1 beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
atpG protein networkhttps://string-db.org/network/1199245.A359_06440ATP synthase, F1 gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the f [...]
atpA protein networkhttps://string-db.org/network/1199245.A359_06450Proton translocating ATP synthase, F1 alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
atpH protein networkhttps://string-db.org/network/1199245.A359_06460ATP synthase, F1 delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the e [...]
atpF protein networkhttps://string-db.org/network/1199245.A359_06470ATP synthase, F0 subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
atpE protein networkhttps://string-db.org/network/1199245.A359_06480ATP synthase, F0 subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extra [...]
atpB protein networkhttps://string-db.org/network/1199245.A359_06490F0F1-type ATP synthase, alpha subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.
mnmG protein networkhttps://string-db.org/network/1199245.A359_06500Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s( [...]
glmU protein networkhttps://string-db.org/network/1199245.A359_06510UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (U [...]
glmS protein networkhttps://string-db.org/network/1199245.A359_06520Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [...]
A359_06530 protein networkhttps://string-db.org/network/1199245.A359_06530Putative salt-induced outer membrane protein; PFAM: Protein of unknown function, DUF481.
dapA protein networkhttps://string-db.org/network/1199245.A359_06540Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
A359_06550 protein networkhttps://string-db.org/network/1199245.A359_06550PFAM: NlpB/DapX lipoprotein.
purC protein networkhttps://string-db.org/network/1199245.A359_06560PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase.
A359_06570 protein networkhttps://string-db.org/network/1199245.A359_06570Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-b [...]
pgk protein networkhttps://string-db.org/network/1199245.A359_06580PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
A359_06620 protein networkhttps://string-db.org/network/1199245.A359_06620PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
parC protein networkhttps://string-db.org/network/1199245.A359_06630DNA topoisomerase IV, A subunit, proteobacterial; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replic [...]
plsB protein networkhttps://string-db.org/network/1199245.A359_06640PFAM: Acyltransferase; TIGRFAM: glycerol-3-phosphate O-acyltransferase; Belongs to the GPAT/DAPAT family.
rpmH protein networkhttps://string-db.org/network/1199245.A359_06660PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type; Belongs to the bacterial ribosomal protein bL34 family.
rnpA protein networkhttps://string-db.org/network/1199245.A359_06670Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]
yidC protein networkhttps://string-db.org/network/1199245.A359_06680Membrane protein insertase, YidC/Oxa1 family, N-terminal domain protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. [...]
mnmE protein networkhttps://string-db.org/network/1199245.A359_06690tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
recB protein networkhttps://string-db.org/network/1199245.A359_06700DNA helicase/exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and proces [...]
tsaD protein networkhttps://string-db.org/network/1199245.A359_06730Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the tran [...]
A359_06740 protein networkhttps://string-db.org/network/1199245.A359_06740Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
A359_06750 protein networkhttps://string-db.org/network/1199245.A359_06750Hypothetical protein.
A359_06760 protein networkhttps://string-db.org/network/1199245.A359_06760Hypothetical protein.
A359_06770 protein networkhttps://string-db.org/network/1199245.A359_06770Hypothetical protein.
recC protein networkhttps://string-db.org/network/1199245.A359_06790DNA helicase/exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and proce [...]
gmk protein networkhttps://string-db.org/network/1199245.A359_06800Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
rpoZ protein networkhttps://string-db.org/network/1199245.A359_06810DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and al [...]
A359_06820 protein networkhttps://string-db.org/network/1199245.A359_06820(p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in [...]
A359_06830 protein networkhttps://string-db.org/network/1199245.A359_06830TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could a [...]
frr protein networkhttps://string-db.org/network/1199245.A359_06890Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
pyrH protein networkhttps://string-db.org/network/1199245.A359_06900Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
tsf protein networkhttps://string-db.org/network/1199245.A359_06910Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis [...]
rpsB protein networkhttps://string-db.org/network/1199245.A359_06920PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family.
map protein networkhttps://string-db.org/network/1199245.A359_06930Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and [...]
truA protein networkhttps://string-db.org/network/1199245.A359_06940Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
pdxB protein networkhttps://string-db.org/network/1199245.A359_06950Phosphoglycerate dehydrogenase-like oxidoreductase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
queC protein networkhttps://string-db.org/network/1199245.A359_06960Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
A359_07010 protein networkhttps://string-db.org/network/1199245.A359_07010Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
A359_07020 protein networkhttps://string-db.org/network/1199245.A359_07020Hypothetical protein.
A359_07060 protein networkhttps://string-db.org/network/1199245.A359_07060PFAM: Polynucleotide kinase 3 phosphatase; TIGRFAM: D,D-heptose 1,7-bisphosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; histidinol-phosphate phosphatase family domain.
A359_07070 protein networkhttps://string-db.org/network/1199245.A359_07070PTS system, glucose subfamily, IIA component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; TIGRFAM: PTS system, glucose subfamily, IIA component.
A359_07080 protein networkhttps://string-db.org/network/1199245.A359_07080Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate ac [...]
A359_07090 protein networkhttps://string-db.org/network/1199245.A359_07090PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
A359_07100 protein networkhttps://string-db.org/network/1199245.A359_07100Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family.
tpiA protein networkhttps://string-db.org/network/1199245.A359_07110Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
A359_07120 protein networkhttps://string-db.org/network/1199245.A359_07120Hypothetical protein.
A359_07130 protein networkhttps://string-db.org/network/1199245.A359_07130Flavodoxin reductase family protein; PFAM: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain.
A359_07180 protein networkhttps://string-db.org/network/1199245.A359_07180Hypothetical protein.
A359_07190 protein networkhttps://string-db.org/network/1199245.A359_07190Hypothetical protein.
mfd protein networkhttps://string-db.org/network/1199245.A359_07240Transcription-repair coupling factor Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncate [...]
A359_07250 protein networkhttps://string-db.org/network/1199245.A359_07250PFAM: Predicted permease; TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family.
lolD protein networkhttps://string-db.org/network/1199245.A359_07260Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
A359_07270 protein networkhttps://string-db.org/network/1199245.A359_07270PFAM: Predicted permease; TIGRFAM: lipoprotein releasing system, transmembrane protein LolE; lipoprotein releasing system, transmembrane protein, LolC/E family.
A359_07310 protein networkhttps://string-db.org/network/1199245.A359_07310PFAM: ABC transporter; TIGRFAM: ATP-binding cassette protein, ChvD family.
A359_07320 protein networkhttps://string-db.org/network/1199245.A359_07320TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain.
deoD protein networkhttps://string-db.org/network/1199245.A359_07330PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD).
deoB protein networkhttps://string-db.org/network/1199245.A359_07340Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
A359_07360 protein networkhttps://string-db.org/network/1199245.A359_07360Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
A359_07380 protein networkhttps://string-db.org/network/1199245.A359_07380PFAM: DNA polymerase III chi subunit, HolC.
valS protein networkhttps://string-db.org/network/1199245.A359_07390valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
A359_07410 protein networkhttps://string-db.org/network/1199245.A359_07410PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase I.
A359_07420 protein networkhttps://string-db.org/network/1199245.A359_07420Lipopolysaccharide heptosyltransferase II; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase II.
hldD protein networkhttps://string-db.org/network/1199245.A359_07430ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the [...]
arnB protein networkhttps://string-db.org/network/1199245.A359_07460Putative PLP-dependent enzyme possibly involved in cell wall biogenesis; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modifie [...]
arnC protein networkhttps://string-db.org/network/1199245.A359_07470Glycosyl transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to [...]
arnA protein networkhttps://string-db.org/network/1199245.A359_07480methionyl-tRNA formyltransferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a fo [...]
arnD protein networkhttps://string-db.org/network/1199245.A359_07490Putative xylanase/chitin deacetylase; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabino [...]
arnT protein networkhttps://string-db.org/network/1199245.A359_07500PMT family glycosyltransferase, 4-amino-4-deoxy-L-arabinose transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modifi [...]
A359_07510 protein networkhttps://string-db.org/network/1199245.A359_07510Hypothetical protein.
arnF protein networkhttps://string-db.org/network/1199245.A359_07520Cation/cationic drug transporter; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membra [...]
A359_07530 protein networkhttps://string-db.org/network/1199245.A359_07530Hypothetical protein.
A359_07540 protein networkhttps://string-db.org/network/1199245.A359_07540Hypothetical protein.
A359_07550 protein networkhttps://string-db.org/network/1199245.A359_07550Hypothetical protein.
trpD protein networkhttps://string-db.org/network/1199245.A359_07560Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranila [...]
trpF protein networkhttps://string-db.org/network/1199245.A359_07570PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpC family.
trpB protein networkhttps://string-db.org/network/1199245.A359_07580Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpA protein networkhttps://string-db.org/network/1199245.A359_07590Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
A359_07600 protein networkhttps://string-db.org/network/1199245.A359_07600Single stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of act [...]
parE protein networkhttps://string-db.org/network/1199245.A359_07620DNA topoisomerase IV, B subunit, proteobacterial; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replic [...]
A359_07630 protein networkhttps://string-db.org/network/1199245.A359_07630Hypothetical protein.
A359_07640 protein networkhttps://string-db.org/network/1199245.A359_07640Hypothetical protein.
A359_07670 protein networkhttps://string-db.org/network/1199245.A359_07670Hypothetical protein.
aroK protein networkhttps://string-db.org/network/1199245.A359_07680Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
A359_07690 protein networkhttps://string-db.org/network/1199245.A359_07690PFAM: D12 class N6 adenine-specific DNA methyltransferase; TIGRFAM: DNA adenine methylase (dam).
A359_07700 protein networkhttps://string-db.org/network/1199245.A359_07700PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
trpS protein networkhttps://string-db.org/network/1199245.A359_07710tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
ftsY protein networkhttps://string-db.org/network/1199245.A359_07720Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the [...]
rpoH protein networkhttps://string-db.org/network/1199245.A359_07730Alternative sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved [...]
lepA protein networkhttps://string-db.org/network/1199245.A359_07740GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
A359_07750 protein networkhttps://string-db.org/network/1199245.A359_07750PFAM: Peptidase S26; Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
rnc protein networkhttps://string-db.org/network/1199245.A359_07760Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
era protein networkhttps://string-db.org/network/1199245.A359_07770GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly als [...]
pdxJ protein networkhttps://string-db.org/network/1199245.A359_07780Pyridoxine 5''-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-ami [...]
acpS protein networkhttps://string-db.org/network/1199245.A359_07790Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
A359_07800 protein networkhttps://string-db.org/network/1199245.A359_07800Hypothetical protein.
A359_07810 protein networkhttps://string-db.org/network/1199245.A359_07810Periplasmic serine protease, Do/DeqQ family; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family; Belongs to the peptidase S1C family.
A359_07820 protein networkhttps://string-db.org/network/1199245.A359_07820PFAM: Protein of unknown function (DUF1043).
A359_07830 protein networkhttps://string-db.org/network/1199245.A359_07830Exopolyphosphatase; PFAM: Ppx/GppA phosphatase family; TIGRFAM: exopolyphosphatase; Belongs to the GppA/Ppx family.
ppk protein networkhttps://string-db.org/network/1199245.A359_07840Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
A359_07850 protein networkhttps://string-db.org/network/1199245.A359_07850PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
zwf protein networkhttps://string-db.org/network/1199245.A359_07860Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
pyrC protein networkhttps://string-db.org/network/1199245.A359_07880Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
rne protein networkhttps://string-db.org/network/1199245.A359_07890Ribonuclease, Rne/Rng family; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in t [...]
A359_07910 protein networkhttps://string-db.org/network/1199245.A359_07910Hypothetical protein.
gpt protein networkhttps://string-db.org/network/1199245.A359_07920PRPP-binding protein, adenine/guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. [...]
priA protein networkhttps://string-db.org/network/1199245.A359_07940Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA [...]
rpmE protein networkhttps://string-db.org/network/1199245.A359_07950Ribosomal protein L31; Binds the 23S rRNA.
guaB protein networkhttps://string-db.org/network/1199245.A359_07960Inosine-5''-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthes [...]
guaA protein networkhttps://string-db.org/network/1199245.A359_07980GMP synthase, PP-ATPase domain/subunit; Catalyzes the synthesis of GMP from XMP.
mntH protein networkhttps://string-db.org/network/1199245.A359_07990Natural resistance-associated macrophage protein metal ion transporter NRAMP; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
gltX protein networkhttps://string-db.org/network/1199245.A359_08020glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
rlmN protein networkhttps://string-db.org/network/1199245.A359_0806023S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the [...]
A359_08070 protein networkhttps://string-db.org/network/1199245.A359_08070Hypothetical protein.
A359_08080 protein networkhttps://string-db.org/network/1199245.A359_08080ATPase component of Mn/Zn ABC-type transporter; PFAM: ABC transporter.
A359_08090 protein networkhttps://string-db.org/network/1199245.A359_08090ABC-type Mn2+/Zn2+ transport system, permease component; PFAM: ABC 3 transport family.
A359_08100 protein networkhttps://string-db.org/network/1199245.A359_08100ABC-type metal ion transport system, periplasmic component/surface adhesin; PFAM: Periplasmic solute binding protein family; Belongs to the bacterial solute-binding protein 9 family.
rplM protein networkhttps://string-db.org/network/1199245.A359_08120Ribosomal protein L13, bacterial type; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the [...]
rpsI protein networkhttps://string-db.org/network/1199245.A359_08130PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family.
queF protein networkhttps://string-db.org/network/1199245.A359_081507-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
A359_08170 protein networkhttps://string-db.org/network/1199245.A359_08170Hypothetical protein.
thiK protein networkhttps://string-db.org/network/1199245.A359_08180Putative choline kinase involved in LPS biosynthesis; Catalyzes the phosphorylation of thiamine to thiamine phosphate.
A359_08190 protein networkhttps://string-db.org/network/1199245.A359_08190Putative lipoprotein; TIGRFAM: uncharacterized proteobacterial lipoprotein.
A359_08210 protein networkhttps://string-db.org/network/1199245.A359_08210HIT family hydrolase, diadenosine tetraphosphate hydrolase; PFAM: HIT domain.
A359_08220 protein networkhttps://string-db.org/network/1199245.A359_08220Hypothetical protein.
A359_08230 protein networkhttps://string-db.org/network/1199245.A359_08230Hydrolase, TatD family; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family.
A359_08240 protein networkhttps://string-db.org/network/1199245.A359_08240PFAM: DNA polymerase III, delta subunit, C terminal; TIGRFAM: DNA polymerase III, delta' subunit.
tmk protein networkhttps://string-db.org/network/1199245.A359_08250Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
acpP protein networkhttps://string-db.org/network/1199245.A359_08280Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
A359_08290 protein networkhttps://string-db.org/network/1199245.A359_082903-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cy [...]
A359_08300 protein networkhttps://string-db.org/network/1199245.A359_08300PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
fabH protein networkhttps://string-db.org/network/1199245.A359_083103-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first [...]
rpmF protein networkhttps://string-db.org/network/1199245.A359_08320PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
A359_08340 protein networkhttps://string-db.org/network/1199245.A359_08340Hypothetical protein.
A359_08350 protein networkhttps://string-db.org/network/1199245.A359_08350Outer membrane protein; PFAM: Surface antigen.
A359_08360 protein networkhttps://string-db.org/network/1199245.A359_08360Hypothetical protein; PFAM: Family of unknown function (DUF490).
ppa protein networkhttps://string-db.org/network/1199245.A359_08370Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
A359_08380 protein networkhttps://string-db.org/network/1199245.A359_08380Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
A359_08390 protein networkhttps://string-db.org/network/1199245.A359_08390Hypothetical protein.
A359_08400 protein networkhttps://string-db.org/network/1199245.A359_08400Hypothetical protein.
A359_08410 protein networkhttps://string-db.org/network/1199245.A359_08410Hypothetical protein.
A359_08420 protein networkhttps://string-db.org/network/1199245.A359_08420PFAM: Inositol monophosphatase family.
A359_08440 protein networkhttps://string-db.org/network/1199245.A359_08440Cysteine desulfurase family protein; PFAM: Aminotransferase class-V.
cysQ protein networkhttps://string-db.org/network/1199245.A359_084503'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
der protein networkhttps://string-db.org/network/1199245.A359_08460Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA [...]
bamB protein networkhttps://string-db.org/network/1199245.A359_08470Beta-barrel assembly machine subunit BamB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
hisS protein networkhttps://string-db.org/network/1199245.A359_08480PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase.
ispG protein networkhttps://string-db.org/network/1199245.A359_084901-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG [...]
A359_08500 protein networkhttps://string-db.org/network/1199245.A359_08500Helix-turn-helix protein.
A359_08510 protein networkhttps://string-db.org/network/1199245.A359_08510Hypothetical protein.
A359_08530 protein networkhttps://string-db.org/network/1199245.A359_08530Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalentl [...]
A359_08540 protein networkhttps://string-db.org/network/1199245.A359_08540Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference fo [...]
A359_08550 protein networkhttps://string-db.org/network/1199245.A359_08550Putative integral membrane protein; PFAM: YGGT family.
A359_08560 protein networkhttps://string-db.org/network/1199245.A359_08560Fe-S cluster protector protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic en [...]
A359_08570 protein networkhttps://string-db.org/network/1199245.A359_08570A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs.
A359_08590 protein networkhttps://string-db.org/network/1199245.A359_08590Oligoketide cyclase/lipid transport protein; PFAM: Polyketide cyclase / dehydrase and lipid transport.
A359_08600 protein networkhttps://string-db.org/network/1199245.A359_08600Hypothetical protein.
bamE protein networkhttps://string-db.org/network/1199245.A359_08610Small protein A (tmRNA-binding); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
erpA protein networkhttps://string-db.org/network/1199245.A359_08620Iron-sulfur cluster assembly accessory protein; Required for insertion of 4Fe-4S clusters for at least IspG.
A359_08630 protein networkhttps://string-db.org/network/1199245.A359_08630Zn-dependent oligopeptidase; PFAM: Peptidase family M3.
rsmJ protein networkhttps://string-db.org/network/1199245.A359_08640Protein of unknown function (DUF548); Specifically methylates the guanosine in position 1516 of 16S rRNA.
A359_08670 protein networkhttps://string-db.org/network/1199245.A359_08670PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
ubiB protein networkhttps://string-db.org/network/1199245.A359_086802-octaprenylphenol hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
A359_08690 protein networkhttps://string-db.org/network/1199245.A359_08690Hypothetical protein; PFAM: SCP-2 sterol transfer family.
ubiE protein networkhttps://string-db.org/network/1199245.A359_08700Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methox [...]
A359_08710 protein networkhttps://string-db.org/network/1199245.A359_08710Hypothetical protein; PFAM: RmuC family.
A359_08720 protein networkhttps://string-db.org/network/1199245.A359_08720Hypothetical protein.
ubiD protein networkhttps://string-db.org/network/1199245.A359_08730UbiD family decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
A359_08740 protein networkhttps://string-db.org/network/1199245.A359_08740Hypothetical protein.
pepQ protein networkhttps://string-db.org/network/1199245.A359_08750Xaa-Pro aminopeptidase; Splits dipeptides with a prolyl residue in the C-terminal position.
hemE protein networkhttps://string-db.org/network/1199245.A359_08770Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
A359_08780 protein networkhttps://string-db.org/network/1199245.A359_08780Putative HD superfamily hydrolase; PFAM: HD domain.
rplS protein networkhttps://string-db.org/network/1199245.A359_08790Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
trmD protein networkhttps://string-db.org/network/1199245.A359_08800tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rimM protein networkhttps://string-db.org/network/1199245.A359_0881016S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19 [...]
rpsP protein networkhttps://string-db.org/network/1199245.A359_08820PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
ffh protein networkhttps://string-db.org/network/1199245.A359_08830Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of [...]
murA protein networkhttps://string-db.org/network/1199245.A359_08850UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
A359_08860 protein networkhttps://string-db.org/network/1199245.A359_08860Putative transcriptional regulator, BolA superfamily; PFAM: BolA-like protein; Belongs to the BolA/IbaG family.
A359_08870 protein networkhttps://string-db.org/network/1199245.A359_08870Hypothetical protein.
A359_08880 protein networkhttps://string-db.org/network/1199245.A359_08880KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein.
lptC protein networkhttps://string-db.org/network/1199245.A359_08890Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS fr [...]
lptA protein networkhttps://string-db.org/network/1199245.A359_08900Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. M [...]
A359_08910 protein networkhttps://string-db.org/network/1199245.A359_08910ABC-type (unclassified) transport system, ATPase component; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter.
A359_08920 protein networkhttps://string-db.org/network/1199245.A359_08920Hypothetical protein.
A359_08930 protein networkhttps://string-db.org/network/1199245.A359_08930PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN.
rapZ protein networkhttps://string-db.org/network/1199245.A359_08940Putative P-loop-containing kinase; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentratio [...]
A359_08950 protein networkhttps://string-db.org/network/1199245.A359_08950Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
dxs protein networkhttps://string-db.org/network/1199245.A359_089601-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (D [...]
A359_08970 protein networkhttps://string-db.org/network/1199245.A359_089702-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
A359_08980 protein networkhttps://string-db.org/network/1199245.A359_08980Hypothetical protein.
A359_08990 protein networkhttps://string-db.org/network/1199245.A359_08990PFAM: Prokaryotic Cytochrome C oxidase subunit IV; TIGRFAM: cytochrome aa3 quinol oxidase, subunit IV; cytochrome o ubiquinol oxidase subunit IV.
A359_09000 protein networkhttps://string-db.org/network/1199245.A359_09000PFAM: Cytochrome c oxidase subunit III; TIGRFAM: cytochrome o ubiquinol oxidase, subunit III.
A359_09010 protein networkhttps://string-db.org/network/1199245.A359_09010PFAM: Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome o ubiquinol oxidase, subunit I; Belongs to the heme-copper respiratory oxidase family.
A359_09020 protein networkhttps://string-db.org/network/1199245.A359_09020PFAM: COX Aromatic Rich Motif; Cytochrome C oxidase subunit II, periplasmic domain; TIGRFAM: cytochrome o ubiquinol oxidase subunit II.
A359_09030 protein networkhttps://string-db.org/network/1199245.A359_09030Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
lysS protein networkhttps://string-db.org/network/1199245.A359_09040lysyl-tRNA synthetase (class II); PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belon [...]
glk protein networkhttps://string-db.org/network/1199245.A359_09060PFAM: Glucokinase; TIGRFAM: glucokinase, proteobacterial type; Belongs to the bacterial glucokinase family.
A359_09090 protein networkhttps://string-db.org/network/1199245.A359_09090Hypothetical protein.
polA protein networkhttps://string-db.org/network/1199245.A359_09100DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
dusA protein networkhttps://string-db.org/network/1199245.A359_09110tRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines [...]
prmB protein networkhttps://string-db.org/network/1199245.A359_09130protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine [...]
A359_09150 protein networkhttps://string-db.org/network/1199245.A359_09150Hypothetical protein.
A359_09160 protein networkhttps://string-db.org/network/1199245.A359_09160Ferritin-like protein; Iron-storage protein.
gshB protein networkhttps://string-db.org/network/1199245.A359_09180PFAM: Prokaryotic glutathione synthetase, N-terminal domain; Prokaryotic glutathione synthetase, ATP-grasp domain; TIGRFAM: glutathione synthetase, prokaryotic; Belongs to the prokaryotic GSH syn [...]
A359_09190 protein networkhttps://string-db.org/network/1199245.A359_09190Hypothetical protein.
A359_09200 protein networkhttps://string-db.org/network/1199245.A359_09200Hypothetical protein.
A359_09210 protein networkhttps://string-db.org/network/1199245.A359_09210Hypothetical protein.
yqgF protein networkhttps://string-db.org/network/1199245.A359_09220Putative endonuclease involved in recombination; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
def protein networkhttps://string-db.org/network/1199245.A359_09230Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
fmt protein networkhttps://string-db.org/network/1199245.A359_09240methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
uvrA protein networkhttps://string-db.org/network/1199245.A359_09260Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed o [...]
ubiA protein networkhttps://string-db.org/network/1199245.A359_092904-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubi [...]
tdk protein networkhttps://string-db.org/network/1199245.A359_09300PFAM: Thymidine kinase.
csrA protein networkhttps://string-db.org/network/1199245.A359_09330Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from ra [...]
alaS protein networkhttps://string-db.org/network/1199245.A359_09340alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
A359_09350 protein networkhttps://string-db.org/network/1199245.A359_09350Uncharacterized protein (competence- and mitomycin-induced); PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family.
htpX protein networkhttps://string-db.org/network/1199245.A359_09390Zn-dependent protease with chaperone function; PFAM: Peptidase family M48; Belongs to the peptidase M48B family.
proQ protein networkhttps://string-db.org/network/1199245.A359_09400Activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-t [...]
A359_09410 protein networkhttps://string-db.org/network/1199245.A359_09410Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; PFAM: Phospholipase D Active site motif.
A359_09420 protein networkhttps://string-db.org/network/1199245.A359_09420Hypothetical protein.
uppS protein networkhttps://string-db.org/network/1199245.A359_09430Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,3 [...]
A359_09440 protein networkhttps://string-db.org/network/1199245.A359_09440CDP-diglyceride synthetase; PFAM: Cytidylyltransferase family.
A359_09450 protein networkhttps://string-db.org/network/1199245.A359_09450RIP metalloprotease RseP; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP.
bamA protein networkhttps://string-db.org/network/1199245.A359_09460Beta-barrel assembly machine subunit BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Consti [...]
A359_09470 protein networkhttps://string-db.org/network/1199245.A359_09470PFAM: Outer membrane protein (OmpH-like); Belongs to the skp family.
lpxD protein networkhttps://string-db.org/network/1199245.A359_09480UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved [...]
fabZ protein networkhttps://string-db.org/network/1199245.A359_09490Beta-hydroxyacyl-(acyl carrier protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated [...]
lpxA protein networkhttps://string-db.org/network/1199245.A359_09500acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer memb [...]
lpxB protein networkhttps://string-db.org/network/1199245.A359_09510lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid t [...]
A359_09520 protein networkhttps://string-db.org/network/1199245.A359_09520PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc).
accA protein networkhttps://string-db.org/network/1199245.A359_09530acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its c [...]
pfkA protein networkhttps://string-db.org/network/1199245.A359_095606-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
mdtG protein networkhttps://string-db.org/network/1199245.A359_09570Arabinose efflux permease family protein; PFAM: Major Facilitator Superfamily.
A359_09580 protein networkhttps://string-db.org/network/1199245.A359_09580Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domai [...]
A359_09590 protein networkhttps://string-db.org/network/1199245.A359_09590Hypothetical protein.
A359_09600 protein networkhttps://string-db.org/network/1199245.A359_09600Hypothetical protein.
A359_09610 protein networkhttps://string-db.org/network/1199245.A359_09610Stress-induced morphogen; PFAM: BolA-like protein; Belongs to the BolA/IbaG family.
tig protein networkhttps://string-db.org/network/1199245.A359_09620Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs t [...]
clpP protein networkhttps://string-db.org/network/1199245.A359_09630ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the d [...]
clpX protein networkhttps://string-db.org/network/1199245.A359_09640Endopeptidase Clp ATP-binding regulatory subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in [...]
lon protein networkhttps://string-db.org/network/1199245.A359_09650ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for [...]
dxr protein networkhttps://string-db.org/network/1199245.A359_096601-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).