Organism Overview: Wigglesworthia glossinidia endosymbiont of Glossina morsitans


 
gidA protein networkhttps://string-db.org/network/1142511.WIGMOR_0001Glucose-inhibited cell-division protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5 [...]
atpB protein networkhttps://string-db.org/network/1142511.WIGMOR_0002F0 sector of membrane-bound ATP synthase, subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain [...]
atpE protein networkhttps://string-db.org/network/1142511.WIGMOR_0003F0 sector of membrane-bound ATP synthase, subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, [...]
atpF protein networkhttps://string-db.org/network/1142511.WIGMOR_0004F0 sector of membrane-bound ATP synthase, subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
atpH protein networkhttps://string-db.org/network/1142511.WIGMOR_0005ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extrame [...]
atpA protein networkhttps://string-db.org/network/1142511.WIGMOR_0006F1 sector of membrane-bound ATP synthase, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
atpG protein networkhttps://string-db.org/network/1142511.WIGMOR_0007F1 sector of membrane-bound ATP synthase, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating [...]
atpD protein networkhttps://string-db.org/network/1142511.WIGMOR_0008F1 sector of membrane-bound ATP synthase, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subuni [...]
atpC protein networkhttps://string-db.org/network/1142511.WIGMOR_0009F1 sector of membrane-bound ATP synthase, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
glmU protein networkhttps://string-db.org/network/1142511.WIGMOR_0010N-acetyl glucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyl transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylgluc [...]
glmS protein networkhttps://string-db.org/network/1142511.WIGMOR_0011L-glutamine:D-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
mnmE protein networkhttps://string-db.org/network/1142511.WIGMOR_00125-methylaminomethyl-2-thiouridine-synthesizing GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble pos [...]
yidC protein networkhttps://string-db.org/network/1142511.WIGMOR_0013Membrane insertion protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins [...]
yidD protein networkhttps://string-db.org/network/1142511.WIGMOR_0014Uncharacterized DUF37 family protein; Could be involved in insertion of integral membrane proteins into the membrane.
rnpA protein networkhttps://string-db.org/network/1142511.WIGMOR_0015Protein C5 component of RNase P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]
rpmH protein networkhttps://string-db.org/network/1142511.WIGMOR_001650S ribosomal subunit protein L34; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL34 family.
dnaN protein networkhttps://string-db.org/network/1142511.WIGMOR_0017DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadi [...]
gyrB protein networkhttps://string-db.org/network/1142511.WIGMOR_0018DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
AFA40881.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0019Protein involved in response to organic substance and cellular membrane organization.
pdxA protein networkhttps://string-db.org/network/1142511.WIGMOR_00214-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decar [...]
ksgA protein networkhttps://string-db.org/network/1142511.WIGMOR_0022S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRN [...]
apaH protein networkhttps://string-db.org/network/1142511.WIGMOR_0023Protein involved in bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity and hydrolase activity.
folA protein networkhttps://string-db.org/network/1142511.WIGMOR_0024Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
carB protein networkhttps://string-db.org/network/1142511.WIGMOR_0025Protein involved in carbamoyl-phosphate synthase activity, catalytic activity, ATP binding, ligase activity, nitrogen compound metabolic process and metabolic process; Belongs to the CarB family.
carA protein networkhttps://string-db.org/network/1142511.WIGMOR_0026Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Protein involved in carbamoyl-phosphate synthase activity, catalytic activity, nitrogen compound metabolic process, gluta [...]
dapB protein networkhttps://string-db.org/network/1142511.WIGMOR_0027Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
ydiK protein networkhttps://string-db.org/network/1142511.WIGMOR_0028Putative inner membrane protein.
pabA protein networkhttps://string-db.org/network/1142511.WIGMOR_0029Aminodeoxychorismate synthase, subunit II; Protein involved in anthranilate synthase activity, catalytic activity, metabolic process, biosynthetic process and glutamine metabolic process.
rpsL protein networkhttps://string-db.org/network/1142511.WIGMOR_003030S ribosomal subunit protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of th [...]
rpsG protein networkhttps://string-db.org/network/1142511.WIGMOR_003130S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subu [...]
fusA protein networkhttps://string-db.org/network/1142511.WIGMOR_0032GTP-binding protein chain elongation factor EF-G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-trans [...]
flhD protein networkhttps://string-db.org/network/1142511.WIGMOR_0033FlhD family flagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons [...]
flhC protein networkhttps://string-db.org/network/1142511.WIGMOR_0034FlhC family flagellar transcriptional activator; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons [...]
motA protein networkhttps://string-db.org/network/1142511.WIGMOR_0035Proton conductor component of flagella motor; Protein involved in protein transporter activity and transport.
motB protein networkhttps://string-db.org/network/1142511.WIGMOR_0036MotB family proton-channel complex protein.
flhB protein networkhttps://string-db.org/network/1142511.WIGMOR_0037Putative flagellar export pore protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus [...]
flhA protein networkhttps://string-db.org/network/1142511.WIGMOR_0038Putative flagellar export pore protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belo [...]
AFA40900.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0039FlgN family flagellar biosynthesis protein; Protein involved in flagellum assembly.
AFA40901.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0040FlgA family flagellar basal-body P-ring formation protein; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for t [...]
flgB protein networkhttps://string-db.org/network/1142511.WIGMOR_0041Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
flgC protein networkhttps://string-db.org/network/1142511.WIGMOR_0042Flagellar component of cell-proximal portion of basal-body rod.
AFA40904.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0043FlgD family flagellar basal-body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.
flgE protein networkhttps://string-db.org/network/1142511.WIGMOR_0044Flagellar hook protein; Protein involved in motor activity, structural molecule activity and ciliary or flagellar motility.
flgF protein networkhttps://string-db.org/network/1142511.WIGMOR_0045Flagellar component of cell-proximal portion of basal-body rod; Protein involved in motor activity, structural molecule activity and ciliary or flagellar motility.
flgG protein networkhttps://string-db.org/network/1142511.WIGMOR_0046Flagellar component of cell-distal portion of basal-body rod; Protein involved in motor activity, structural molecule activity, cellular component movement, flagellum organization and ciliary or [...]
flgH protein networkhttps://string-db.org/network/1142511.WIGMOR_0047Flagellar protein of basal-body outer-membrane L ring; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
flgI protein networkhttps://string-db.org/network/1142511.WIGMOR_0048Putative flagellar basal body protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
AFA40910.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0049FlgJ family peptidoglycan hydrolase.
flgK protein networkhttps://string-db.org/network/1142511.WIGMOR_0050FlgK family flagellar hook-associated protein; Protein involved in structural molecule activity and flagellum assembly.
AFA40912.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0051FlgL family flagellar hook-associated protein; Protein involved in structural molecule activity and ciliary or flagellar motility.
fliR protein networkhttps://string-db.org/network/1142511.WIGMOR_0052Flagellar export pore protein; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.
fliQ protein networkhttps://string-db.org/network/1142511.WIGMOR_0053Flagellar biosynthesis protein; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.
fliP protein networkhttps://string-db.org/network/1142511.WIGMOR_0054Flagellar biosynthesis protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
AFA40916.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0055FliO family protein; Protein involved in flagellum organization.
fliN protein networkhttps://string-db.org/network/1142511.WIGMOR_0056Flagellar motor switching and energizing component; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. Th [...]
AFA40918.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0057Protein involved in motor activity, ciliary or flagellar motility and chemotaxis.
fliL protein networkhttps://string-db.org/network/1142511.WIGMOR_0058Flagellar biosynthesis protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
AFA40920.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0059FliK family flagellar hook-length control protein; Protein involved in motor activity and flagellum assembly.
fliI protein networkhttps://string-db.org/network/1142511.WIGMOR_0061Flagellum-specific ATP synthase; Frameshift mutation relative to Escherichia coli K-12 MG1655 (ASAP:ABE-0006462); has termination codon at position 109; flagellar export apparatus chaperone (pseu [...]
AFA40922.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0062FliH family flagellar assembly protein; Protein involved in motor activity and ciliary or flagellar motility.
fliG protein networkhttps://string-db.org/network/1142511.WIGMOR_0063Protein involved in motor activity, ciliary or flagellar motility and chemotaxis.
fliF protein networkhttps://string-db.org/network/1142511.WIGMOR_0064Flagellar basal-body MS-ring and collar protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
fliE protein networkhttps://string-db.org/network/1142511.WIGMOR_0065Flagellar basal-body component; Protein involved in motor activity, structural molecule activity and ciliary or flagellar motility.
fliS protein networkhttps://string-db.org/network/1142511.WIGMOR_0066Flagellin chaperone; Protein involved in flagellum assembly.
AFA40927.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0067FliD family flagellar hook-associated protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of g [...]
AFA40928.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0068FliC family flagellar biosynthesis protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
yceA protein networkhttps://string-db.org/network/1142511.WIGMOR_0069Rhodanese-related sulfurtransferase; Belongs to the UPF0176 family.
mdoH protein networkhttps://string-db.org/network/1142511.WIGMOR_0070Glycosyl transferase; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
gloB protein networkhttps://string-db.org/network/1142511.WIGMOR_0071Putative hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
rnhA protein networkhttps://string-db.org/network/1142511.WIGMOR_0072Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
dnaQ protein networkhttps://string-db.org/network/1142511.WIGMOR_0073DNA polymerase III epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing funct [...]
yhhF protein networkhttps://string-db.org/network/1142511.WIGMOR_0074Ribosomal RNA small subunit methyltransferase D; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD [...]
ftsY protein networkhttps://string-db.org/network/1142511.WIGMOR_0075Signal recognition particle (SRP) receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal [...]
rpoH protein networkhttps://string-db.org/network/1142511.WIGMOR_0076RNA polymerase, sigma 32 (sigma H) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor [...]
hemL protein networkhttps://string-db.org/network/1142511.WIGMOR_0077Glutamate-1-semialdehyde aminotransferase (aminomutase); Protein involved in glutamate-1-semialdehyde 2,1-aminomutase activity, transaminase activity, pyridoxal phosphate binding, catalytic activ [...]
erpA protein networkhttps://string-db.org/network/1142511.WIGMOR_0078A-type Fe-S protein; Protein involved in structural molecule activity, iron-sulfur cluster binding and iron-sulfur cluster assembly; Belongs to the HesB/IscA family.
mltC protein networkhttps://string-db.org/network/1142511.WIGMOR_0079Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
yggX protein networkhttps://string-db.org/network/1142511.WIGMOR_0080Iron-sulfur cluster protector protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynth [...]
mutY protein networkhttps://string-db.org/network/1142511.WIGMOR_0081Protein involved in DNA N-glycosylase activity, catalytic activity, hydrolase activity, base-excision repair and DNA repair.
yggV protein networkhttps://string-db.org/network/1142511.WIGMOR_0082dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleot [...]
proC protein networkhttps://string-db.org/network/1142511.WIGMOR_0083Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
yggS protein networkhttps://string-db.org/network/1142511.WIGMOR_0084Pyridoxal 5'-phosphate dependent enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
thrS protein networkhttps://string-db.org/network/1142511.WIGMOR_0085threonyl-tRNA synthetase; Protein involved in threonine-tRNA ligase activity, ATP binding, ligase activity, forming aminoacyl-tRNA and related compounds, nucleotide binding, aminoacyl-tRNA ligase [...]
infC protein networkhttps://string-db.org/network/1142511.WIGMOR_0086Protein chain initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus en [...]
rpmI protein networkhttps://string-db.org/network/1142511.WIGMOR_008750S ribosomal subunit protein L35; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL35 family.
rplT protein networkhttps://string-db.org/network/1142511.WIGMOR_008850S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesiz [...]
pheS protein networkhttps://string-db.org/network/1142511.WIGMOR_0089Phenylalanine tRNA synthetase, alpha subunit; Protein involved in nucleotide binding, phenylalanine-tRNA ligase activity, ATP binding, tRNA binding, aminoacyl-tRNA ligase activity, phenylalanyl-t [...]
pheT protein networkhttps://string-db.org/network/1142511.WIGMOR_0090Phenylalanine tRNA synthetase, beta subunit; Protein involved in magnesium ion binding, phenylalanine-tRNA ligase activity, ATP binding, RNA binding, tRNA binding, nucleotide binding, phenylalany [...]
pyrC protein networkhttps://string-db.org/network/1142511.WIGMOR_0091Dihydro-orotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
AFA40952.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0092Protein involved in ribonuclease activity, RNA binding and RNA processing.
rluC protein networkhttps://string-db.org/network/1142511.WIGMOR_0093Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
rpmF protein networkhttps://string-db.org/network/1142511.WIGMOR_009450S ribosomal subunit protein L32; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL32 family.
fabD protein networkhttps://string-db.org/network/1142511.WIGMOR_0095malonyl-CoA-[acyl-carrier-protein] transacylase; Protein involved in [acyl-carrier-protein] S-malonyltransferase activity, catalytic activity, binding, transferase activity, fatty acid biosynthet [...]
fabG protein networkhttps://string-db.org/network/1142511.WIGMOR_00963-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cy [...]
acpP protein networkhttps://string-db.org/network/1142511.WIGMOR_0097Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis.
pabC protein networkhttps://string-db.org/network/1142511.WIGMOR_00984-amino-4-deoxychorismate lyase component of para-aminobenzoate synthase multienzyme complex; Protein involved in 4-amino-4-deoxychorismate lyase activity, pyridoxal phosphate binding, catalytic [...]
yceG protein networkhttps://string-db.org/network/1142511.WIGMOR_0099Putative aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
tmk protein networkhttps://string-db.org/network/1142511.WIGMOR_0100Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
AFA40961.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0101DNA polymerase III delta prime subunit; Protein involved in DNA binding, DNA-directed DNA polymerase activity and DNA replication.
ycfH protein networkhttps://string-db.org/network/1142511.WIGMOR_0102Putative metallodependent hydrolase; Protein involved in endodeoxyribonuclease activity, producing 5'-phosphomonoesters.
hinT protein networkhttps://string-db.org/network/1142511.WIGMOR_0103Purine nucleoside phosphoramidase; Protein involved in catalytic activity.
ndh protein networkhttps://string-db.org/network/1142511.WIGMOR_0104Respiratory NADH dehydrogenase 2/cupric reductase; Protein involved in oxidoreductase activity and oxidation-reduction process.
AFA40965.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0105Transcription-repair coupling factor; Protein involved in sequence-specific DNA binding transcription factor activity, damaged DNA binding, helicase activity, ATP binding, nucleic acid binding, A [...]
lolC protein networkhttps://string-db.org/network/1142511.WIGMOR_0106Membrane component of an ABC superfamily outer membrane-specific lipoprotein transporter.
lolD protein networkhttps://string-db.org/network/1142511.WIGMOR_0107ATP-binding component of an ABC superfamily outer membrane-specific lipoprotein transporter; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-de [...]
lolE protein networkhttps://string-db.org/network/1142511.WIGMOR_0108Membrane component of an ABC superfamily outer membrane-specific lipoprotein transporter.
purB protein networkhttps://string-db.org/network/1142511.WIGMOR_0109Adenylosuccinate lyase; Protein involved in N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity, catalytic activity, IMP biosynthetic process and purine ribonucleotide biosynthetic p [...]
mnmA protein networkhttps://string-db.org/network/1142511.WIGMOR_0110tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of [...]
htpX protein networkhttps://string-db.org/network/1142511.WIGMOR_0111Protein involved in metalloendopeptidase activity and proteolysis; Belongs to the peptidase M48B family.
yoaE protein networkhttps://string-db.org/network/1142511.WIGMOR_0112Putative membrane protein; Protein involved in protein binding.
pabB protein networkhttps://string-db.org/network/1142511.WIGMOR_0113Aminodeoxychorismate synthase, subunit I; Protein involved in oxo-acid-lyase activity, biosynthetic process and folic acid-containing compound biosynthetic process.
sppA protein networkhttps://string-db.org/network/1142511.WIGMOR_0114Protease IV (signal peptide peptidase); Protein involved in peptidase activity, proteolysis and signal peptide processing.
gapA protein networkhttps://string-db.org/network/1142511.WIGMOR_0115Glyceraldehyde-3-phosphate dehydrogenase A; Protein involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, glyceraldehyde-3-phosphate dehydro [...]
nadK protein networkhttps://string-db.org/network/1142511.WIGMOR_0117NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of [...]
AFA40977.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0118Oligoketide cyclase.
smpB protein networkhttps://string-db.org/network/1142511.WIGMOR_0119Trans-translation protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosome [...]
aspS protein networkhttps://string-db.org/network/1142511.WIGMOR_0121aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
ruvC protein networkhttps://string-db.org/network/1142511.WIGMOR_0122Endonuclease component of RuvABC resolvasome; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to str [...]
znuB protein networkhttps://string-db.org/network/1142511.WIGMOR_0123Membrane component of a high-affinity zinc uptake system; Protein involved in ATP binding, ATPase activity, coupled to transmembrane movement of substances and transport.
znuC protein networkhttps://string-db.org/network/1142511.WIGMOR_0124ATP-binding component of a high-affinity zinc uptake system; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs t [...]
znuA protein networkhttps://string-db.org/network/1142511.WIGMOR_0125Periplasmic component of a high-affinity zinc uptake system; Protein involved in metal ion binding, metal ion transport and cell adhesion; Belongs to the bacterial solute-binding protein 9 family [...]
yebA protein networkhttps://string-db.org/network/1142511.WIGMOR_0126Putative peptidase.
mntH protein networkhttps://string-db.org/network/1142511.WIGMOR_0127Manganese transport protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
ubiE protein networkhttps://string-db.org/network/1142511.WIGMOR_01292-octaprenyl-6-methoxy-1,4-benzoquinone methylase/S-adenosylmethionine:2-DMK methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) an [...]
ubiB protein networkhttps://string-db.org/network/1142511.WIGMOR_01302-octaprenylphenol hydroxylase of ubiquinone biosynthetic pathway; Protein involved in transferase activity, transferring phosphorus-containing groups and ubiquinone biosynthetic process.
ubiD protein networkhttps://string-db.org/network/1142511.WIGMOR_01313-octaprenyl-4-hydroxybenzoate decarboxylase; Protein involved in carboxy-lyase activity and ubiquinone biosynthetic process; Belongs to the UbiD family.
trkH protein networkhttps://string-db.org/network/1142511.WIGMOR_0132Potassium transporter; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.
hemG protein networkhttps://string-db.org/network/1142511.WIGMOR_0133Protoporphyrin oxidase, flavoprotein.
accC protein networkhttps://string-db.org/network/1142511.WIGMOR_0138acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier [...]
accB protein networkhttps://string-db.org/network/1142511.WIGMOR_0139Acetyl CoA carboxylase, BCCP subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and th [...]
aroQ protein networkhttps://string-db.org/network/1142511.WIGMOR_01403-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
mreB protein networkhttps://string-db.org/network/1142511.WIGMOR_0141MreB family actin-like cell wall component; Protein involved in ATP binding and cell morphogenesis.
mreC protein networkhttps://string-db.org/network/1142511.WIGMOR_0142MreC family transmembrane cell wall component; Involved in formation and maintenance of cell shape.
mreD protein networkhttps://string-db.org/network/1142511.WIGMOR_0143MreD family transmembrane cell wall component; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the Mr [...]
pgi protein networkhttps://string-db.org/network/1142511.WIGMOR_0144Protein involved in glucose-6-phosphate isomerase activity, gluconeogenesis and glycolysis; Belongs to the GPI family.
proS protein networkhttps://string-db.org/network/1142511.WIGMOR_0145prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
mrcB protein networkhttps://string-db.org/network/1142511.WIGMOR_0148Penicillin-binding protein 1B (PBP1B); Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-termin [...]
sodA protein networkhttps://string-db.org/network/1142511.WIGMOR_0149Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
glyS protein networkhttps://string-db.org/network/1142511.WIGMOR_0150Glycine tRNA synthetase, beta subunit; Protein involved in nucleotide binding, glycine-tRNA ligase activity, ATP binding and glycyl-tRNA aminoacylation.
glyQ protein networkhttps://string-db.org/network/1142511.WIGMOR_0151Glycine tRNA synthetase, alpha subunit; Protein involved in nucleotide binding, glycine-tRNA ligase activity, ATP binding and glycyl-tRNA aminoacylation.
AFA41003.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0152Putative membrane protein.
thrA protein networkhttps://string-db.org/network/1142511.WIGMOR_0153Bifunctional aspartokinase I/homoserine dehydrogenase I; Protein involved in oxidoreductase activity, NADP binding, aspartate kinase activity, binding, homoserine dehydrogenase activity, cellular [...]
pyrI protein networkhttps://string-db.org/network/1142511.WIGMOR_0154Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
glnA protein networkhttps://string-db.org/network/1142511.WIGMOR_0155Glutamine synthetase; Protein involved in glutamate-ammonia ligase activity, catalytic activity, nitrogen compound metabolic process, glutamine biosynthetic process and nitrogen fixation.
ydjM protein networkhttps://string-db.org/network/1142511.WIGMOR_0156Putative inner membrane protein.
asnB protein networkhttps://string-db.org/network/1142511.WIGMOR_0157Asparagine synthetase B; Protein involved in asparagine synthase (glutamine-hydrolyzing) activity and asparagine biosynthetic process.
emrE protein networkhttps://string-db.org/network/1142511.WIGMOR_0161Multidrug resistance protein.
bioH protein networkhttps://string-db.org/network/1142511.WIGMOR_0162Carboxylesterase; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid syn [...]
hemF protein networkhttps://string-db.org/network/1142511.WIGMOR_0163Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vin [...]
talA protein networkhttps://string-db.org/network/1142511.WIGMOR_0164Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily.
AFA41013.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0165Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
trpS protein networkhttps://string-db.org/network/1142511.WIGMOR_0166tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
rpe protein networkhttps://string-db.org/network/1142511.WIGMOR_0167Protein involved in ribulose-phosphate 3-epimerase activity, catalytic activity, carbohydrate metabolic process and metabolic process; Belongs to the ribulose-phosphate 3-epimerase family.
AFA41016.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0168DamX family protein.
aroB protein networkhttps://string-db.org/network/1142511.WIGMOR_01693-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
aroK protein networkhttps://string-db.org/network/1142511.WIGMOR_0170Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
pck protein networkhttps://string-db.org/network/1142511.WIGMOR_0171Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucl [...]
der protein networkhttps://string-db.org/network/1142511.WIGMOR_0173Putative lipoprotein; Frameshift mutation relative to Escherichia coli K-12 MG1655 (ASAP:ABE-0008270); has termination codon at position 264; ribosome biogenesis GTPase (pseudogene).
AFA41021.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0174Putative membrane protein; Protein involved in binding.
hisS protein networkhttps://string-db.org/network/1142511.WIGMOR_0175Histidyl tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding, histidine-tRNA ligase activity, tRNA aminoacylation for protein translation and hist [...]
ispG protein networkhttps://string-db.org/network/1142511.WIGMOR_01761-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG [...]
AFA41024.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0177Putative DNA-binding protein; Protein involved in DNA binding.
rlmN protein networkhttps://string-db.org/network/1142511.WIGMOR_017823S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofrea [...]
ndk protein networkhttps://string-db.org/network/1142511.WIGMOR_0179Nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the [...]
rplQ protein networkhttps://string-db.org/network/1142511.WIGMOR_018050S ribosomal subunit protein L17; Protein involved in structural constituent of ribosome and translation.
rpoA protein networkhttps://string-db.org/network/1142511.WIGMOR_0181RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpsD protein networkhttps://string-db.org/network/1142511.WIGMOR_018230S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpsK protein networkhttps://string-db.org/network/1142511.WIGMOR_018330S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosom [...]
rpsM protein networkhttps://string-db.org/network/1142511.WIGMOR_018430S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and pr [...]
rpmJ protein networkhttps://string-db.org/network/1142511.WIGMOR_018550S ribosomal subunit protein L36; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL36 family.
secY protein networkhttps://string-db.org/network/1142511.WIGMOR_0186Preprotein translocase membrane subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate [...]
rplO protein networkhttps://string-db.org/network/1142511.WIGMOR_018750S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
rpmD protein networkhttps://string-db.org/network/1142511.WIGMOR_018850S ribosomal subunit protein L30; Protein involved in structural constituent of ribosome and translation.
rpsE protein networkhttps://string-db.org/network/1142511.WIGMOR_018930S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein [...]
rplR protein networkhttps://string-db.org/network/1142511.WIGMOR_019050S ribosomal subunit protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central p [...]
rplF protein networkhttps://string-db.org/network/1142511.WIGMOR_019150S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and ne [...]
rpsH protein networkhttps://string-db.org/network/1142511.WIGMOR_019230S ribosomal subunit protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Bel [...]
rpsN protein networkhttps://string-db.org/network/1142511.WIGMOR_019330S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs t [...]
rplE protein networkhttps://string-db.org/network/1142511.WIGMOR_019450S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central prot [...]
rplX protein networkhttps://string-db.org/network/1142511.WIGMOR_019550S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplN protein networkhttps://string-db.org/network/1142511.WIGMOR_019650S ribosomal subunit protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rpsQ protein networkhttps://string-db.org/network/1142511.WIGMOR_019730S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rpmC protein networkhttps://string-db.org/network/1142511.WIGMOR_019850S ribosomal subunit protein L29; Protein involved in structural constituent of ribosome and translation; Belongs to the universal ribosomal protein uL29 family.
rplP protein networkhttps://string-db.org/network/1142511.WIGMOR_019950S ribosomal subunit protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsC protein networkhttps://string-db.org/network/1142511.WIGMOR_020030S ribosomal subunit protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 fami [...]
rplV protein networkhttps://string-db.org/network/1142511.WIGMOR_020150S ribosomal subunit protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines [...]
rpsS protein networkhttps://string-db.org/network/1142511.WIGMOR_020230S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplB protein networkhttps://string-db.org/network/1142511.WIGMOR_020350S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond format [...]
rplW protein networkhttps://string-db.org/network/1142511.WIGMOR_020450S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the m [...]
rplD protein networkhttps://string-db.org/network/1142511.WIGMOR_020550S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel.
rplC protein networkhttps://string-db.org/network/1142511.WIGMOR_020650S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rpsJ protein networkhttps://string-db.org/network/1142511.WIGMOR_020730S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
AFA41055.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0208Rhodanese-like domain protein.
grxC protein networkhttps://string-db.org/network/1142511.WIGMOR_0209Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
gpsA protein networkhttps://string-db.org/network/1142511.WIGMOR_0210Glycerol-3-phosphate dehydrogenase; Protein involved in oxidoreductase activity, acting on CH-OH group of donors, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acce [...]
cpxA protein networkhttps://string-db.org/network/1142511.WIGMOR_0211Two-component regulatory system sensory histidine kinase; Protein involved in ATP binding, transferase activity, transferring phosphorus-containing groups, signal transducer activity, phosphoryla [...]
cpxR protein networkhttps://string-db.org/network/1142511.WIGMOR_0212Protein involved in two-component response regulator activity, DNA binding, two-component signal transduction system (phosphorelay) and regulation of transcription, DNA-dependent.
dcd protein networkhttps://string-db.org/network/1142511.WIGMOR_02132'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
metG protein networkhttps://string-db.org/network/1142511.WIGMOR_0214methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
rluD protein networkhttps://string-db.org/network/1142511.WIGMOR_021523S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
AFA41063.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0216Putative lipoprotein precursor.
ftsB protein networkhttps://string-db.org/network/1142511.WIGMOR_0217Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, whi [...]
ispD protein networkhttps://string-db.org/network/1142511.WIGMOR_02182-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to [...]
ispF protein networkhttps://string-db.org/network/1142511.WIGMOR_02192C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
yccA protein networkhttps://string-db.org/network/1142511.WIGMOR_0220Inner membrane protein; Belongs to the BI1 family.
hemH protein networkhttps://string-db.org/network/1142511.WIGMOR_0222Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
adk protein networkhttps://string-db.org/network/1142511.WIGMOR_0223Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
htpG protein networkhttps://string-db.org/network/1142511.WIGMOR_0224Molecular chaperone HSP90 family; Molecular chaperone. Has ATPase activity.
ybaB protein networkhttps://string-db.org/network/1142511.WIGMOR_0225DNA-binding protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
dnaX protein networkhttps://string-db.org/network/1142511.WIGMOR_0226DNA polymerase III gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' t [...]
hha protein networkhttps://string-db.org/network/1142511.WIGMOR_0227Hemolysin expression modulating protein.
rpoC protein networkhttps://string-db.org/network/1142511.WIGMOR_0228RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/1142511.WIGMOR_0229RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/1142511.WIGMOR_023050S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs t [...]
rplJ protein networkhttps://string-db.org/network/1142511.WIGMOR_023150S ribosomal subunit protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal riboso [...]
rplA protein networkhttps://string-db.org/network/1142511.WIGMOR_023250S ribosomal subunit protein L1; Protein involved in RNA binding, structural constituent of ribosome and translation; Belongs to the universal ribosomal protein uL1 family.
rplK protein networkhttps://string-db.org/network/1142511.WIGMOR_023350S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/1142511.WIGMOR_0234Transcription termination factor; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polym [...]
secE protein networkhttps://string-db.org/network/1142511.WIGMOR_0235Preprotein translocase membrane subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation [...]
tuf protein networkhttps://string-db.org/network/1142511.WIGMOR_0236Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
coaA protein networkhttps://string-db.org/network/1142511.WIGMOR_0241Protein involved in pantothenate kinase activity, ATP binding, kinase activity, coenzyme A biosynthetic process and metabolic process.
birA protein networkhttps://string-db.org/network/1142511.WIGMOR_0242biotin-[acetylCoA carboxylase] holoenzyme synthetase/DNA-binding transcriptional repressor; Protein involved in catalytic activity, biotin-[acetyl-CoA-carboxylase] ligase activity and protein mod [...]
murB protein networkhttps://string-db.org/network/1142511.WIGMOR_0243FAD-binding UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
purH protein networkhttps://string-db.org/network/1142511.WIGMOR_0244Protein involved in catalytic activity, IMP cyclohydrolase activity, phosphoribosylaminoimidazolecarboxamide formyltransferase activity and purine nucleotide biosynthetic process.
purD protein networkhttps://string-db.org/network/1142511.WIGMOR_0245Protein involved in catalytic activity, ATP binding, phosphoribosylamine-glycine ligase activity, ligase activity and purine base biosynthetic process; Belongs to the GARS family.
hupA protein networkhttps://string-db.org/network/1142511.WIGMOR_0246HU, DNA-binding transcriptional regulator, alpha subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme env [...]
hemE protein networkhttps://string-db.org/network/1142511.WIGMOR_0247Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
thiC protein networkhttps://string-db.org/network/1142511.WIGMOR_0248Thiamin (pyrimidine moiety) biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-ade [...]
thiE protein networkhttps://string-db.org/network/1142511.WIGMOR_0249Thiamin phosphate synthase (thiamin phosphate pyrophosphorylase); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosph [...]
thiS protein networkhttps://string-db.org/network/1142511.WIGMOR_0251Sulfur carrier protein; A single nucleotide substitution within codon 168 relative to Escherichia coli K-12 MG1655 (ASAP:ABE-0013053) results in a termination codon; thiazole biosynthesis adenyly [...]
thiG protein networkhttps://string-db.org/network/1142511.WIGMOR_0252Thiamin biosynthesis ThiGH complex subunit; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thi [...]
thiH protein networkhttps://string-db.org/network/1142511.WIGMOR_0253Thiamin biosynthesis ThiGH complex subunit; Protein involved in iron-sulfur cluster binding, catalytic activity, iron ion binding, 4 iron, 4 sulfur cluster binding, cofactor metabolic process, me [...]
hspQ protein networkhttps://string-db.org/network/1142511.WIGMOR_0254Hemimethylated DNA-binding protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.
rpiA protein networkhttps://string-db.org/network/1142511.WIGMOR_0255Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
glyA protein networkhttps://string-db.org/network/1142511.WIGMOR_0256Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
ssb protein networkhttps://string-db.org/network/1142511.WIGMOR_0257ssDNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA [...]
dnaB protein networkhttps://string-db.org/network/1142511.WIGMOR_0258Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
plsC protein networkhttps://string-db.org/network/1142511.WIGMOR_0259Protein involved in acyltransferase activity, 1-acylglycerol-3-phosphate O-acyltransferase activity, metabolic process and phospholipid biosynthetic process; Belongs to the 1-acyl-sn-glycerol-3-p [...]
aroE protein networkhttps://string-db.org/network/1142511.WIGMOR_0260NAD(P)-binding dehydroshikimate reductase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction [...]
yrdC protein networkhttps://string-db.org/network/1142511.WIGMOR_0261Putative ribosome maturation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the [...]
def protein networkhttps://string-db.org/network/1142511.WIGMOR_0262Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
fmt protein networkhttps://string-db.org/network/1142511.WIGMOR_026310-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the [...]
trkA protein networkhttps://string-db.org/network/1142511.WIGMOR_0264NAD-binding component of TrK potassium transporter; Protein involved in cation transmembrane transporter activity, binding and potassium ion transport.
sdaC protein networkhttps://string-db.org/network/1142511.WIGMOR_0265Putative serine transporter.
trxB protein networkhttps://string-db.org/network/1142511.WIGMOR_0266Protein involved in oxidoreductase activity, thioredoxin-disulfide reductase activity, oxidation-reduction process and removal of superoxide radicals.
lolA protein networkhttps://string-db.org/network/1142511.WIGMOR_0268Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue [...]
serS protein networkhttps://string-db.org/network/1142511.WIGMOR_0269seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
ahpC protein networkhttps://string-db.org/network/1142511.WIGMOR_0270Alkyl hydroperoxide reductase, C22 subunit; Protein involved in antioxidant activity, oxidoreductase activity, peroxiredoxin activity and oxidation-reduction process.
serC protein networkhttps://string-db.org/network/1142511.WIGMOR_02713-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phos [...]
aroA protein networkhttps://string-db.org/network/1142511.WIGMOR_02723-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
cmk protein networkhttps://string-db.org/network/1142511.WIGMOR_0273Protein involved in cytidylate kinase activity, ATP binding and nucleobase, nucleoside, nucleotide and nucleic acid metabolic process.
rpsA protein networkhttps://string-db.org/network/1142511.WIGMOR_027430S ribosomal subunit protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
AFA41115.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0275Surface antigen.
AFA41116.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0276Putative exported protein.
ppa protein networkhttps://string-db.org/network/1142511.WIGMOR_0277Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
fbp protein networkhttps://string-db.org/network/1142511.WIGMOR_0278Protein involved in phosphoric ester hydrolase activity and carbohydrate metabolic process; Belongs to the FBPase class 1 family.
ispB protein networkhttps://string-db.org/network/1142511.WIGMOR_0279Octaprenyl diphosphate synthase; Protein involved in isoprenoid biosynthetic process; Belongs to the FPP/GGPP synthase family.
rplU protein networkhttps://string-db.org/network/1142511.WIGMOR_028050S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
rpmA protein networkhttps://string-db.org/network/1142511.WIGMOR_028150S ribosomal subunit protein L27; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL27 family.
obgE protein networkhttps://string-db.org/network/1142511.WIGMOR_0282DNA repair and cell partioning GTPase; Protein involved in GTP binding, magnesium ion binding and GTPase activity.
ubiF protein networkhttps://string-db.org/network/1142511.WIGMOR_02832-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase; Protein involved in oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of mol [...]
folB protein networkhttps://string-db.org/network/1142511.WIGMOR_02857,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
ygjD protein networkhttps://string-db.org/network/1142511.WIGMOR_0286Putative peptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of [...]
rpsU protein networkhttps://string-db.org/network/1142511.WIGMOR_028730S ribosomal subunit protein S21; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bS21 family.
dnaG protein networkhttps://string-db.org/network/1142511.WIGMOR_0288DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpoD protein networkhttps://string-db.org/network/1142511.WIGMOR_0289RNA polymerase, sigma 70 (sigma D) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor [...]
pgpA protein networkhttps://string-db.org/network/1142511.WIGMOR_0292Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
thiL protein networkhttps://string-db.org/network/1142511.WIGMOR_0293Thiamin-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thia [...]
AFA41132.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0294Protein involved in RNA binding and regulation of transcription, DNA-dependent.
AFA41133.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0295NusB family protein; Protein involved in RNA binding and regulation of transcription, DNA-dependent.
ribE protein networkhttps://string-db.org/network/1142511.WIGMOR_0296Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is t [...]
ribD protein networkhttps://string-db.org/network/1142511.WIGMOR_0297Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphat [...]
pyrB protein networkhttps://string-db.org/network/1142511.WIGMOR_0298Aspartate carbamoyltransferase, catalytic subunit; Protein involved in amino acid binding, carboxyl- or carbamoyltransferase activity, aspartate carbamoyltransferase activity, cellular amino acid [...]
valS protein networkhttps://string-db.org/network/1142511.WIGMOR_0299valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
pepA protein networkhttps://string-db.org/network/1142511.WIGMOR_0300Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
AFA41139.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0301Putative membrane protein.
yjgQ protein networkhttps://string-db.org/network/1142511.WIGMOR_0302Conserved inner membrane protein.
bioD protein networkhttps://string-db.org/network/1142511.WIGMOR_0303Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ur [...]
bioC protein networkhttps://string-db.org/network/1142511.WIGMOR_0304malonyl-CoA methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesi [...]
bioF protein networkhttps://string-db.org/network/1142511.WIGMOR_03058-amino-7-oxononanoate synthase; Protein involved in transferase activity, transferring nitrogenous groups, pyridoxal phosphate binding, catalytic activity and biosynthetic process.
bioB protein networkhttps://string-db.org/network/1142511.WIGMOR_0306Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily [...]
bioA protein networkhttps://string-db.org/network/1142511.WIGMOR_0307Protein involved in adenosylmethionine-8-amino-7-oxononanoate transaminase activity, transaminase activity, pyridoxal phosphate binding, catalytic activity and biotin biosynthetic process; Belong [...]
yraP protein networkhttps://string-db.org/network/1142511.WIGMOR_0308Putative phospholipid-binding protein.
yraL protein networkhttps://string-db.org/network/1142511.WIGMOR_0309Putative methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
panB protein networkhttps://string-db.org/network/1142511.WIGMOR_03113-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to [...]
panC protein networkhttps://string-db.org/network/1142511.WIGMOR_0312Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
ybeY protein networkhttps://string-db.org/network/1142511.WIGMOR_0313Uncharacterized UPF0054 family protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
lnt protein networkhttps://string-db.org/network/1142511.WIGMOR_0314Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrol [...]
gyrA protein networkhttps://string-db.org/network/1142511.WIGMOR_0315DNA gyrase (type II topoisomerase), subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and [...]
ubiG protein networkhttps://string-db.org/network/1142511.WIGMOR_0316Bifunctional 3-demethylubiquinone-9 3-methyltransferase/2-octaprenyl-6-hydroxy phenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathwa [...]
asd protein networkhttps://string-db.org/network/1142511.WIGMOR_0317NAD(P)-binding aspartate-semialdehyde dehydrogenase; Protein involved in N-acetyl-gamma-glutamyl-phosphate reductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of dono [...]
yhgN protein networkhttps://string-db.org/network/1142511.WIGMOR_0318Putative antibiotic transporter.
lysS protein networkhttps://string-db.org/network/1142511.WIGMOR_0319Lysine tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding, nucleic acid binding, lysine-tRNA ligase activity, tRNA aminoacylation for protein tra [...]
prfB protein networkhttps://string-db.org/network/1142511.WIGMOR_0320Peptide chain release factor RF-2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
ygfY protein networkhttps://string-db.org/network/1142511.WIGMOR_0322Uncharacterized DUF339 family protein; Frameshift mutation relative to Escherichia coli K-12 MG1655 (ASAP:ABE-0009492); has termination codon at position 131; ssDNA-specific exonuclease (pseudoge [...]
AFA41159.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0323Protein involved in aminomethyltransferase activity and glycine catabolic process; Belongs to the GcvT family.
pfs protein networkhttps://string-db.org/network/1142511.WIGMOR_03245'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) [...]
ligA protein networkhttps://string-db.org/network/1142511.WIGMOR_0326DNA ligase, NAD(+)-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and a [...]
putA protein networkhttps://string-db.org/network/1142511.WIGMOR_0327Transcriptional repressor/proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; be [...]
zapA protein networkhttps://string-db.org/network/1142511.WIGMOR_0328Protein that localizes to the cytokinetic ring; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessa [...]
pepP protein networkhttps://string-db.org/network/1142511.WIGMOR_0329Protein involved in aminopeptidase activity, manganese ion binding and cellular process.
ubiH protein networkhttps://string-db.org/network/1142511.WIGMOR_0330FAD/NAD(P)-binding 2-octaprenyl-6-methoxyphenol hydroxylase; Protein involved in oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of mole [...]
yqjA protein networkhttps://string-db.org/network/1142511.WIGMOR_0331Conserved inner membrane protein.
orn protein networkhttps://string-db.org/network/1142511.WIGMOR_0332Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
psd protein networkhttps://string-db.org/network/1142511.WIGMOR_0333Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
yjeP protein networkhttps://string-db.org/network/1142511.WIGMOR_0334Putative mechanosensitive channel; Protein involved in transmembrane transport.
poxA protein networkhttps://string-db.org/network/1142511.WIGMOR_0335Putative lysyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding, lysine-tRNA ligase activity, tRNA aminoacylation for protein translation and l [...]
fldA protein networkhttps://string-db.org/network/1142511.WIGMOR_0336Flavodoxin 1; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
pgm protein networkhttps://string-db.org/network/1142511.WIGMOR_0337Phosphoglucomutase; Protein involved in intramolecular transferase activity, phosphotransferases and carbohydrate metabolic process.
ybgI protein networkhttps://string-db.org/network/1142511.WIGMOR_0338Metal-binding predicted hydrolase-oxidase.
sdhC protein networkhttps://string-db.org/network/1142511.WIGMOR_0339Cytochrome b556-binding succinate dehydrogenase membrane subunit; Overlaps another CDS with the same product name; Protein involved in succinate dehydrogenase activity, oxidoreductase activity, a [...]
sdhD protein networkhttps://string-db.org/network/1142511.WIGMOR_0340Cytochrome b556-binding succinate dehydrogenase membrane subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
sdhA protein networkhttps://string-db.org/network/1142511.WIGMOR_0341Succinate dehydrogenase flavoprotein subunit; Protein involved in oxidoreductase activity, oxidoreductase activity, acting on the CH-CH group of donors, flavin adenine dinucleotide binding, elect [...]
sdhB protein networkhttps://string-db.org/network/1142511.WIGMOR_0342Succinate dehydrogenase FeS subunit; Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle and oxidation-reduction process.
sucA protein networkhttps://string-db.org/network/1142511.WIGMOR_0343Thiamin-requiring 2-oxoglutarate decarboxylase; Protein involved in oxoglutarate dehydrogenase (succinyl-transferring) activity, thiamine pyrophosphate binding, oxidoreductase activity, acting on [...]
sucB protein networkhttps://string-db.org/network/1142511.WIGMOR_0344Dihydrolipoyltranssuccinase; Protein involved in dihydrolipoyllysine-residue succinyltransferase activity, acyltransferase activity, tricarboxylic acid cycle and metabolic process.
sucC protein networkhttps://string-db.org/network/1142511.WIGMOR_0345succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus rep [...]
sucD protein networkhttps://string-db.org/network/1142511.WIGMOR_0346succinyl-CoA synthetase, NAD(P)-binding, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or [...]
tolQ protein networkhttps://string-db.org/network/1142511.WIGMOR_0347TolAQR complex membrane spanning protein; Protein involved in protein transporter activity, protein transport and transport.
tolR protein networkhttps://string-db.org/network/1142511.WIGMOR_0348TolAQR complex membrane spanning protein; Protein involved in transporter activity and transport.
AFA41184.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0349TolA family protein; Protein involved in transporter activity and transport.
tolB protein networkhttps://string-db.org/network/1142511.WIGMOR_0350Periplasmic protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a [...]
pal protein networkhttps://string-db.org/network/1142511.WIGMOR_0351Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer memb [...]
ybgF protein networkhttps://string-db.org/network/1142511.WIGMOR_0352SecB-dependent secretory protein; Protein involved in binding and protein binding.
prmB protein networkhttps://string-db.org/network/1142511.WIGMOR_0354Ribosomal protein L3 N5-glutamine methyltransferase; Protein involved in site-specific DNA-methyltransferase (adenine-specific) activity, protein methyltransferase activity, methyltransferase act [...]
aroC protein networkhttps://string-db.org/network/1142511.WIGMOR_0355Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
fabB protein networkhttps://string-db.org/network/1142511.WIGMOR_03563-oxoacyl-[acyl-carrier-protein] synthase I; Protein involved in catalytic activity, biosynthetic process and metabolic process; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP syntha [...]
AFA41191.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0357MarR family transcriptional regulator; Protein involved in sequence-specific DNA binding transcription factor activity and regulation of transcription, DNA-dependent.
gmk protein networkhttps://string-db.org/network/1142511.WIGMOR_0358Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
rpoZ protein networkhttps://string-db.org/network/1142511.WIGMOR_0359RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
rpmG protein networkhttps://string-db.org/network/1142511.WIGMOR_036050S ribosomal subunit protein L33; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/1142511.WIGMOR_036150S ribosomal subunit protein L28; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL28 family.
dfp protein networkhttps://string-db.org/network/1142511.WIGMOR_0362FMN-binding 4'-phosphopantothenoylcysteine decarboxylase/phosphopantothenoylcysteine synthetase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to [...]
dut protein networkhttps://string-db.org/network/1142511.WIGMOR_0363Deoxyuridinetriphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration o [...]
pyrE protein networkhttps://string-db.org/network/1142511.WIGMOR_0364Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
tilS protein networkhttps://string-db.org/network/1142511.WIGMOR_0366tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is [...]
prlC protein networkhttps://string-db.org/network/1142511.WIGMOR_0367Protein involved in metalloendopeptidase activity and proteolysis.
marC protein networkhttps://string-db.org/network/1142511.WIGMOR_0368Putative transporter.
cutA protein networkhttps://string-db.org/network/1142511.WIGMOR_0370Copper binding protein; Protein involved in response to metal ion.
aspA protein networkhttps://string-db.org/network/1142511.WIGMOR_0371Aspartate ammonia-lyase; Protein involved in catalytic activity, aspartate ammonia-lyase activity, lyase activity, aspartate metabolic process and tricarboxylic acid cycle.
dapD protein networkhttps://string-db.org/network/1142511.WIGMOR_0372Protein involved in transferase activity, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity and lysine biosynthetic process via diaminopimelate; Belongs to the transfera [...]
map protein networkhttps://string-db.org/network/1142511.WIGMOR_0373Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
rpsB protein networkhttps://string-db.org/network/1142511.WIGMOR_037430S ribosomal subunit protein S2; Protein involved in structural constituent of ribosome and translation; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/1142511.WIGMOR_0375Protein chain elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrol [...]
frr protein networkhttps://string-db.org/network/1142511.WIGMOR_0376Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
dxr protein networkhttps://string-db.org/network/1142511.WIGMOR_03771-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).
ispU protein networkhttps://string-db.org/network/1142511.WIGMOR_0378Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-F [...]
cdsA protein networkhttps://string-db.org/network/1142511.WIGMOR_0379CDP-diglyceride synthase; Protein involved in transferase activity, transferring phosphorus-containing groups; Belongs to the CDS family.
rseP protein networkhttps://string-db.org/network/1142511.WIGMOR_0380Inner membrane zinc RIP metalloprotease; Protein involved in protein binding, metalloendopeptidase activity and proteolysis.
bamA protein networkhttps://string-db.org/network/1142511.WIGMOR_0381Outer membrane beta-barrel protein assembly factor.
skp protein networkhttps://string-db.org/network/1142511.WIGMOR_0382Periplasmic chaperone; Protein involved in unfolded protein binding; Belongs to the skp family.
lpxD protein networkhttps://string-db.org/network/1142511.WIGMOR_0383UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved [...]
fabZ protein networkhttps://string-db.org/network/1142511.WIGMOR_0384(3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated an [...]
lpxA protein networkhttps://string-db.org/network/1142511.WIGMOR_0385UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
lpxB protein networkhttps://string-db.org/network/1142511.WIGMOR_0386tetraacyldisaccharide-1-P synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycoli [...]
dnaE protein networkhttps://string-db.org/network/1142511.WIGMOR_0387DNA polymerase III alpha subunit; Protein involved in catalytic activity, 3'-5' exonuclease activity, nucleic acid binding, DNA binding, DNA-directed DNA polymerase activity and DNA replication.
accA protein networkhttps://string-db.org/network/1142511.WIGMOR_0388acetyl-CoA carboxylase, carboxytransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its car [...]
cvrA protein networkhttps://string-db.org/network/1142511.WIGMOR_0389Putative cation/proton antiporter; Protein involved in solute:hydrogen antiporter activity, cation transmembrane transporter activity, cation transport, transmembrane transport and potassium ion [...]
dadX protein networkhttps://string-db.org/network/1142511.WIGMOR_0390PLP-binding alanine racemase 2; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
minC protein networkhttps://string-db.org/network/1142511.WIGMOR_0391Cell division inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed [...]
minD protein networkhttps://string-db.org/network/1142511.WIGMOR_0392Protein involved in ATPase activity, barrier septum site selection and ATP catabolic process.
minE protein networkhttps://string-db.org/network/1142511.WIGMOR_0393Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures c [...]
AFA41226.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0394Putative metal-dependent protease molecular chaperone; Protein involved in metalloendopeptidase activity and proteolysis.
xthA protein networkhttps://string-db.org/network/1142511.WIGMOR_0395Exonuclease III; Protein involved in nuclease activity, DNA binding, endonuclease activity and DNA repair.
purU protein networkhttps://string-db.org/network/1142511.WIGMOR_0396Protein involved in formyltetrahydrofolate deformylase activity, hydroxymethyl-, formyl- and related transferase activity, 'de novo' IMP biosynthetic process and biosynthetic process.
galU protein networkhttps://string-db.org/network/1142511.WIGMOR_0397Glucose-1-phosphate uridylyltransferase; Protein involved in nucleotidyltransferase activity and biosynthetic process.
AFA41230.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0398UDP-glucose dehydrogenase; Protein involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, NAD binding, oxidoreductase activity, binding and oxidation-r [...]
hns protein networkhttps://string-db.org/network/1142511.WIGMOR_0399Global DNA-binding transcriptional dual regulator H-NS; Protein involved in DNA binding and regulation of transcription, DNA-dependent; Belongs to the histone-like protein H-NS family.
cls protein networkhttps://string-db.org/network/1142511.WIGMOR_0400Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
yciC protein networkhttps://string-db.org/network/1142511.WIGMOR_0401Putative inner membrane protein.
yciK protein networkhttps://string-db.org/network/1142511.WIGMOR_0402Putative oxoacyl-[acyl carrier protein] reductase; Protein involved in binding, oxidoreductase activity and metabolic process.
ribA protein networkhttps://string-db.org/network/1142511.WIGMOR_0403GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
pyrF protein networkhttps://string-db.org/network/1142511.WIGMOR_0404Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamil [...]
fabI protein networkhttps://string-db.org/network/1142511.WIGMOR_0405NADH-dependent enoyl-[acyl-carrier-protein] reductase; Protein involved in binding, oxidoreductase activity and metabolic process.
sufA protein networkhttps://string-db.org/network/1142511.WIGMOR_0406Fe-S cluster assembly protein; Protein involved in structural molecule activity, iron-sulfur cluster binding and iron-sulfur cluster assembly; Belongs to the HesB/IscA family.
sufB protein networkhttps://string-db.org/network/1142511.WIGMOR_0407Component of SufBCD complex; Protein involved in iron-sulfur cluster assembly.
sufC protein networkhttps://string-db.org/network/1142511.WIGMOR_0408Fe-S cluster assembly transport protein; Protein involved in ATP binding, ATPase activity, nucleotide binding, nucleoside-triphosphatase activity and transport.
sufD protein networkhttps://string-db.org/network/1142511.WIGMOR_0409Component of SufBCD complex; Protein involved in iron-sulfur cluster assembly.
sufS protein networkhttps://string-db.org/network/1142511.WIGMOR_0410PLP-dependent selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-co [...]
sufE protein networkhttps://string-db.org/network/1142511.WIGMOR_0411Sulfur acceptor protein.
AFA41244.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0412Major outer membrane lipoprotein.
pyrG protein networkhttps://string-db.org/network/1142511.WIGMOR_0413CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the [...]
eno protein networkhttps://string-db.org/network/1142511.WIGMOR_0414Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
ybiS protein networkhttps://string-db.org/network/1142511.WIGMOR_0415L,D-transpeptidase; Protein involved in transferase activity.
ychF protein networkhttps://string-db.org/network/1142511.WIGMOR_0416Putative GTP-binding protein; Protein involved in GTP binding.
pth protein networkhttps://string-db.org/network/1142511.WIGMOR_0417peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
prsA protein networkhttps://string-db.org/network/1142511.WIGMOR_0418Phosphoribosylpyrophosphate synthase; Protein involved in magnesium ion binding, ribose phosphate diphosphokinase activity, nucleotide biosynthetic process and nucleoside metabolic process.
ispE protein networkhttps://string-db.org/network/1142511.WIGMOR_04194-diphosphocytidyl-2-C-methylerythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE [...]
hemA protein networkhttps://string-db.org/network/1142511.WIGMOR_0421Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
prfA protein networkhttps://string-db.org/network/1142511.WIGMOR_0422Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
prmC protein networkhttps://string-db.org/network/1142511.WIGMOR_0423Release factors RF-1 and RF-2 N5-glutamine methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally cons [...]
kdsA protein networkhttps://string-db.org/network/1142511.WIGMOR_04243-deoxy-D-manno-octulosonate 8-phosphate synthase; Protein involved in 3-deoxy-8-phosphooctulonate synthase activity, catalytic activity, metabolic process and biosynthetic process; Belongs to th [...]
nadE protein networkhttps://string-db.org/network/1142511.WIGMOR_0425NAD synthetase, NH3/glutamine-dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
fumC protein networkhttps://string-db.org/network/1142511.WIGMOR_0426Fumarate hydratase (fumarase C),aerobic Class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase famil [...]
AFA41258.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0427Putative endonuclease; Protein involved in catalytic activity and metabolic process.
nth protein networkhttps://string-db.org/network/1142511.WIGMOR_0428DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various d [...]
tyrS protein networkhttps://string-db.org/network/1142511.WIGMOR_0429tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
pdxH protein networkhttps://string-db.org/network/1142511.WIGMOR_0430Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
slyA protein networkhttps://string-db.org/network/1142511.WIGMOR_0431DNA-binding transcriptional activator; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.
rnt protein networkhttps://string-db.org/network/1142511.WIGMOR_0432Ribonuclease T (RNase T); Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the ter [...]
grxD protein networkhttps://string-db.org/network/1142511.WIGMOR_0433Monothiol glutaredoxin; Protein involved in electron carrier activity, protein disulfide oxidoreductase activity and cell redox homeostasis; Belongs to the glutaredoxin family. Monothiol subfamil [...]
ribC protein networkhttps://string-db.org/network/1142511.WIGMOR_0434Riboflavin synthase, alpha subunit; Protein involved in riboflavin synthase activity, oxidoreductase activity, riboflavin biosynthetic process and oxidation-reduction process.
purM protein networkhttps://string-db.org/network/1142511.WIGMOR_0436Phosphoribosylaminoimidazole synthetase; Protein involved in phosphoribosylformylglycinamidine cyclo-ligase activity, catalytic activity and 'de novo' IMP biosynthetic process.
dapA protein networkhttps://string-db.org/network/1142511.WIGMOR_0437Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
purC protein networkhttps://string-db.org/network/1142511.WIGMOR_0438Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Protein involved in phosphoribosylaminoimidazolesuccinocarboxamide synthase activity, ATP binding, ligase activity and purine nucleotid [...]
murA protein networkhttps://string-db.org/network/1142511.WIGMOR_0439UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
yrbA protein networkhttps://string-db.org/network/1142511.WIGMOR_0440Putative DNA-binding transcriptional regulator; Belongs to the BolA/IbaG family.
kdsD protein networkhttps://string-db.org/network/1142511.WIGMOR_0441D-arabinose 5-phosphate isomerase; Protein involved in isomerase activity, sugar binding, protein binding and carbohydrate metabolic process.
yhbG protein networkhttps://string-db.org/network/1142511.WIGMOR_0442Putative ATP-binding component of an ABC superfamily transporter; Protein involved in ATP binding and ATPase activity.
AFA41273.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0443YhbN family protein.
lptC protein networkhttps://string-db.org/network/1142511.WIGMOR_0444Lipopolysaccharide transport protein.
AFA41275.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0445Hypothetical protein.
nadC protein networkhttps://string-db.org/network/1142511.WIGMOR_0446Quinolinate phosphoribosyltransferase; Protein involved in nicotinate-nucleotide diphosphorylase (carboxylating) activity, transferase activity, transferring pentosyl groups, catalytic activity, [...]
aceE protein networkhttps://string-db.org/network/1142511.WIGMOR_0447Thiamin-binding pyruvate dehydrogenase, decarboxylase component E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2 [...]
aceF protein networkhttps://string-db.org/network/1142511.WIGMOR_0448Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; Protein involved in acyltransferase activity and metabolic process.
lpd protein networkhttps://string-db.org/network/1142511.WIGMOR_0449Lipoamide dehydrogenase; Protein involved in dihydrolipoyl dehydrogenase activity, flavin adenine dinucleotide binding, oxidoreductase activity, oxidation-reduction process and cell redox homeost [...]
thyA protein networkhttps://string-db.org/network/1142511.WIGMOR_0450Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate [...]
lgt protein networkhttps://string-db.org/network/1142511.WIGMOR_0451Phosphatidylglycerol-prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of [...]
thiD protein networkhttps://string-db.org/network/1142511.WIGMOR_0452Bifunctional hydroxy-methylpyrimidine kinase/hydroxy-phosphomethylpyrimidine kinase; Protein involved in phosphomethylpyrimidine kinase activity and thiamine biosynthetic process.
folE protein networkhttps://string-db.org/network/1142511.WIGMOR_0453Protein involved in GTP cyclohydrolase I activity and tetrahydrofolate biosynthetic process.
metK protein networkhttps://string-db.org/network/1142511.WIGMOR_0454Methionine adenosyltransferase 1; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet form [...]
pgsA protein networkhttps://string-db.org/network/1142511.WIGMOR_0455Phosphatidylglycerophosphate synthetase; Protein involved in CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity, phosphotransferase activity, for other substituted phospha [...]
ubiX protein networkhttps://string-db.org/network/1142511.WIGMOR_04593-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylas [...]
purF protein networkhttps://string-db.org/network/1142511.WIGMOR_0460Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine p [...]
cvpA protein networkhttps://string-db.org/network/1142511.WIGMOR_0461Membrane protein required for colicin V production; Protein involved in toxin biosynthetic process.
folC protein networkhttps://string-db.org/network/1142511.WIGMOR_0462Bifunctional folylpolyglutamate synthase/dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to d [...]
accD protein networkhttps://string-db.org/network/1142511.WIGMOR_0463acetyl-CoA carboxylase carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carri [...]
truA protein networkhttps://string-db.org/network/1142511.WIGMOR_0464tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
pdxB protein networkhttps://string-db.org/network/1142511.WIGMOR_0465Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
surE protein networkhttps://string-db.org/network/1142511.WIGMOR_04675'/3'-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates wit [...]
fbaA protein networkhttps://string-db.org/network/1142511.WIGMOR_0468Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-b [...]
pgk protein networkhttps://string-db.org/network/1142511.WIGMOR_0469Protein involved in phosphoglycerate kinase activity and glycolysis; Belongs to the phosphoglycerate kinase family.
trxA protein networkhttps://string-db.org/network/1142511.WIGMOR_0470Thioredoxin 1; Protein involved in electron carrier activity, protein disulfide oxidoreductase activity, glycerol ether metabolic process and cell redox homeostasis; Belongs to the thioredoxin fa [...]
rho protein networkhttps://string-db.org/network/1142511.WIGMOR_0471Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and releas [...]
rffA protein networkhttps://string-db.org/network/1142511.WIGMOR_0472dTDP-4-keto-6-deoxy-D-glucose aminotransferase; Protein involved in catalytic activity and pyridoxal phosphate binding; Belongs to the DegT/DnrJ/EryC1 family.
gntY protein networkhttps://string-db.org/network/1142511.WIGMOR_0476Putative gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the matura [...]
fabA protein networkhttps://string-db.org/network/1142511.WIGMOR_0477Beta-hydroxydecanoyl thioester dehydrase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and t [...]
dnaK protein networkhttps://string-db.org/network/1142511.WIGMOR_0478Chaperone Hsp70, co-chaperone with DnaJ; Acts as a chaperone; Belongs to the heat shock protein 70 family.
dnaJ protein networkhttps://string-db.org/network/1142511.WIGMOR_0479Chaperone Hsp40, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating prot [...]
nhaA protein networkhttps://string-db.org/network/1142511.WIGMOR_0480Sodium-proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
rpsT protein networkhttps://string-db.org/network/1142511.WIGMOR_048130S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA.
ribF protein networkhttps://string-db.org/network/1142511.WIGMOR_0482Bifunctional riboflavin kinase/FAD synthetase; Protein involved in FMN adenylyltransferase activity, riboflavin kinase activity and riboflavin biosynthetic process; Belongs to the ribF family.
ileS protein networkhttps://string-db.org/network/1142511.WIGMOR_0483isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
lspA protein networkhttps://string-db.org/network/1142511.WIGMOR_0484Prolipoprotein signal peptidase (signal peptidase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
ispH protein networkhttps://string-db.org/network/1142511.WIGMOR_04851-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 4Fe-4S protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosph [...]
purT protein networkhttps://string-db.org/network/1142511.WIGMOR_0486Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N [...]
waaA protein networkhttps://string-db.org/network/1142511.WIGMOR_04873-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP [...]
coaD protein networkhttps://string-db.org/network/1142511.WIGMOR_0488Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD [...]
glnS protein networkhttps://string-db.org/network/1142511.WIGMOR_0489glutamyl-tRNA synthetase; Protein involved in nucleotide binding, ATP binding, ligase activity, forming aminoacyl-tRNA and related compounds, glutamine-tRNA ligase activity, aminoacyl-tRNA ligase [...]
efp protein networkhttps://string-db.org/network/1142511.WIGMOR_0490Elongation factor EF-P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly [...]
yjeK protein networkhttps://string-db.org/network/1142511.WIGMOR_0491Lysine 2,3-aminomutase; Protein involved in catalytic activity, iron-sulfur cluster binding and metabolic process.
AFA41315.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0492Putative membrane protein precursor.
suhB protein networkhttps://string-db.org/network/1142511.WIGMOR_0493Protein involved in inositol or phosphatidylinositol phosphatase activity; Belongs to the inositol monophosphatase superfamily.
iscS protein networkhttps://string-db.org/network/1142511.WIGMOR_0494Cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process.
dapE protein networkhttps://string-db.org/network/1142511.WIGMOR_0496Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in [...]
yadH protein networkhttps://string-db.org/network/1142511.WIGMOR_0497Membrane component of an ABC superfamily transporter; Protein involved in transporter activity and transport.
yadG protein networkhttps://string-db.org/network/1142511.WIGMOR_0498Putative ATP-binding component of an ABC superfamily transporter; Protein involved in nucleotide binding, nucleoside-triphosphatase activity, ATP binding and ATPase activity.
rpmE protein networkhttps://string-db.org/network/1142511.WIGMOR_049950S ribosomal subunit protein L31; Binds the 23S rRNA.
hslV protein networkhttps://string-db.org/network/1142511.WIGMOR_0501ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
hslU protein networkhttps://string-db.org/network/1142511.WIGMOR_0502Molecular chaperone and ATPase component of HslUV protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hyd [...]
emrD protein networkhttps://string-db.org/network/1142511.WIGMOR_0503Multidrug efflux system protein; Protein involved in transmembrane transport.
fpr protein networkhttps://string-db.org/network/1142511.WIGMOR_0504Protein involved in oxidoreductase activity and oxidation-reduction process.
tpiA protein networkhttps://string-db.org/network/1142511.WIGMOR_0505Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
corA protein networkhttps://string-db.org/network/1142511.WIGMOR_0506Magnesium/nickel/cobalt transporter; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
yigB protein networkhttps://string-db.org/network/1142511.WIGMOR_0507FMN phosphatase; Protein involved in phosphoglycolate phosphatase activity, catalytic activity and metabolic process.
dapF protein networkhttps://string-db.org/network/1142511.WIGMOR_0508Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
AFA41330.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0509Protein involved in transporter activity and transport.
amiC protein networkhttps://string-db.org/network/1142511.WIGMOR_0511Exodeoxyribonuclease V alpha chain; Frameshift mutation relative to Escherichia coli K-12 MG1655 (ASAP:ABE-0009238); has termination codon at position 132; N-acetylmuramoyl-L-alanine amidase (pse [...]
recB protein networkhttps://string-db.org/network/1142511.WIGMOR_0512Exonuclease V (RecBCD complex), beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive [...]
recC protein networkhttps://string-db.org/network/1142511.WIGMOR_0513Exodeoxyribonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-depend [...]
folK protein networkhttps://string-db.org/network/1142511.WIGMOR_05142-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Protein involved in 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity and folic acid-containing compou [...]
asnS protein networkhttps://string-db.org/network/1142511.WIGMOR_0515Asparaginyl tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding, asparagine-tRNA ligase activity, nucleic acid binding, tRNA aminoacylation for pr [...]
rpsF protein networkhttps://string-db.org/network/1142511.WIGMOR_051630S ribosomal subunit protein S6; Binds together with S18 to 16S ribosomal RNA.
rpsR protein networkhttps://string-db.org/network/1142511.WIGMOR_051730S ribosomal subunit protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial [...]
rplI protein networkhttps://string-db.org/network/1142511.WIGMOR_051850S ribosomal subunit protein L9; Binds to the 23S rRNA.
AFA41339.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0519Hypothetical protein.
groS protein networkhttps://string-db.org/network/1142511.WIGMOR_0520Cpn10 chaperonin GroES, small subunit of GroESL; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
groL protein networkhttps://string-db.org/network/1142511.WIGMOR_0521Cpn60 chaperonin GroEL, large subunit of GroESL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
dsbA protein networkhttps://string-db.org/network/1142511.WIGMOR_0522Protein involved in protein disulfide oxidoreductase activity.
AFA41343.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0523Protein involved in DNA binding, 5'-3' exonuclease activity and catalytic activity.
yajC protein networkhttps://string-db.org/network/1142511.WIGMOR_0524SecYEG protein translocase auxillary subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins [...]
msbA protein networkhttps://string-db.org/network/1142511.WIGMOR_0525Membrane component of an ABC superfamily lipid transporter; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane doma [...]
ycaR protein networkhttps://string-db.org/network/1142511.WIGMOR_0527UPF0434 protein WIGMOR_0527; Contains multiple defects relative to Wigglesworthia brevipalpis (ASAP:ACB-0135752); has termination codon at position 102; tetraacyldisaccharide 4'-kinase (pseudogen [...]
kdsB protein networkhttps://string-db.org/network/1142511.WIGMOR_05283-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
rplS protein networkhttps://string-db.org/network/1142511.WIGMOR_052950S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
trmD protein networkhttps://string-db.org/network/1142511.WIGMOR_0530tRNA (guanine-1-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rimM protein networkhttps://string-db.org/network/1142511.WIGMOR_053116S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Ess [...]
rpsP protein networkhttps://string-db.org/network/1142511.WIGMOR_053230S ribosomal subunit protein S16; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bS16 family.
ffh protein networkhttps://string-db.org/network/1142511.WIGMOR_0533Signal Recognition Particle (SRP) component with 4.5S RNA (ffs); Protein involved in 7S RNA binding, GTP binding, nucleotide binding, nucleoside-triphosphatase activity and SRP-dependent cotransl [...]
gshA protein networkhttps://string-db.org/network/1142511.WIGMOR_0534Protein involved in glutamate-cysteine ligase activity and glutathione biosynthetic process; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
purK protein networkhttps://string-db.org/network/1142511.WIGMOR_0535N5-carboxyaminoimidazole ribonucleotide synthase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosy [...]
purE protein networkhttps://string-db.org/network/1142511.WIGMOR_0536N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
lpxH protein networkhttps://string-db.org/network/1142511.WIGMOR_0537UDP-2,3-diacylglucosamine pyrophosphatase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of [...]
cysS protein networkhttps://string-db.org/network/1142511.WIGMOR_0538cysteinyl-tRNA synthetase; Protein involved in nucleotide binding, cysteine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, cysteinyl-tRNA aminoacylation and tRNA aminoacylatio [...]
folD protein networkhttps://string-db.org/network/1142511.WIGMOR_0539Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10 [...]
hemD protein networkhttps://string-db.org/network/1142511.WIGMOR_0541Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
hemC protein networkhttps://string-db.org/network/1142511.WIGMOR_0542Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
infA protein networkhttps://string-db.org/network/1142511.WIGMOR_0543Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
cca protein networkhttps://string-db.org/network/1142511.WIGMOR_0544tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'-nucleotidase/phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucle [...]
ribB protein networkhttps://string-db.org/network/1142511.WIGMOR_05453,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
aroF protein networkhttps://string-db.org/network/1142511.WIGMOR_05463-deoxy-D-arabino-heptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7- [...]
recA protein networkhttps://string-db.org/network/1142511.WIGMOR_0547DNA strand exchange/recombination protease/nuclease; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and [...]
alaS protein networkhttps://string-db.org/network/1142511.WIGMOR_0548alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
greA protein networkhttps://string-db.org/network/1142511.WIGMOR_0551Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a [...]
rrmJ protein networkhttps://string-db.org/network/1142511.WIGMOR_055223 S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
ftsH protein networkhttps://string-db.org/network/1142511.WIGMOR_0553Subunit of integral membrane ATP-dependent zinc metallopeptidase; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality [...]
folP protein networkhttps://string-db.org/network/1142511.WIGMOR_05547,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immedi [...]
glmM protein networkhttps://string-db.org/network/1142511.WIGMOR_0555Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
secG protein networkhttps://string-db.org/network/1142511.WIGMOR_0556Preprotein translocase membrane subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
nusA protein networkhttps://string-db.org/network/1142511.WIGMOR_0559Transcription termination/antitermination L factor; Participates in both transcription termination and antitermination.
infB protein networkhttps://string-db.org/network/1142511.WIGMOR_0560Translation initiation factor IF2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to t [...]
rbfA protein networkhttps://string-db.org/network/1142511.WIGMOR_056130s ribosome binding factor; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but [...]
truB protein networkhttps://string-db.org/network/1142511.WIGMOR_0562tRNA U55 pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily [...]
rpsO protein networkhttps://string-db.org/network/1142511.WIGMOR_056330S ribosomal subunit protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
pnp protein networkhttps://string-db.org/network/1142511.WIGMOR_0564Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
deaD protein networkhttps://string-db.org/network/1142511.WIGMOR_0565ATP-dependent RNA helicase; Protein involved in nucleic acid binding, helicase activity, ATP binding and ATP-dependent helicase activity; Belongs to the DEAD box helicase family.
mdlA protein networkhttps://string-db.org/network/1142511.WIGMOR_0566Putative ATP-binding component of multidrug ABC transporter; Protein involved in ATP binding, ATPase activity, coupled to transmembrane movement of substances, nucleotide binding, nucleoside-trip [...]
mdlB protein networkhttps://string-db.org/network/1142511.WIGMOR_0567Putative ATP-binding component of multidrug ABC transporter; Protein involved in ATP binding, ATPase activity, coupled to transmembrane movement of substances, nucleotide binding, nucleoside-trip [...]
gpmA protein networkhttps://string-db.org/network/1142511.WIGMOR_0568Phosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
ddlA protein networkhttps://string-db.org/network/1142511.WIGMOR_0569D-alanine-D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
holE protein networkhttps://string-db.org/network/1142511.WIGMOR_0570DNA polymerase III, theta subunit; Protein involved in DNA binding, DNA-directed DNA polymerase activity and DNA replication.
rsgA protein networkhttps://string-db.org/network/1142511.WIGMOR_0571Ferritin iron storage protein; Iron-storage protein.
mraW protein networkhttps://string-db.org/network/1142511.WIGMOR_0572S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ftsI protein networkhttps://string-db.org/network/1142511.WIGMOR_0573Septal peptidoglycan synthesis transpeptidase (penicillin-binding protein 3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
murE protein networkhttps://string-db.org/network/1142511.WIGMOR_0574UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso- diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (U [...]
murF protein networkhttps://string-db.org/network/1142511.WIGMOR_0575UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murei [...]
mraY protein networkhttps://string-db.org/network/1142511.WIGMOR_0576phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY su [...]
murD protein networkhttps://string-db.org/network/1142511.WIGMOR_0577UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDE [...]
ftsW protein networkhttps://string-db.org/network/1142511.WIGMOR_0578Cell division membrane protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
murG protein networkhttps://string-db.org/network/1142511.WIGMOR_0579Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
murC protein networkhttps://string-db.org/network/1142511.WIGMOR_0580UDP-N-acetylmuramate:L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
ftsQ protein networkhttps://string-db.org/network/1142511.WIGMOR_0581Divisome localization and recruitment protein; Essential cell division protein.
ftsA protein networkhttps://string-db.org/network/1142511.WIGMOR_0582Cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
ftsZ protein networkhttps://string-db.org/network/1142511.WIGMOR_0583GTP-binding tubulin-like cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assem [...]
lpxC protein networkhttps://string-db.org/network/1142511.WIGMOR_0584UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A bi [...]
secA protein networkhttps://string-db.org/network/1142511.WIGMOR_0585Preprotein translocase subunit, ATPase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP [...]
fliA protein networkhttps://string-db.org/network/1142511.WIGMOR_0586RNA polymerase, sigma 28 (sigma F) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor [...]
acpS protein networkhttps://string-db.org/network/1142511.WIGMOR_0587Holo-[acyl-carrier-protein] synthase 1; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
pdxJ protein networkhttps://string-db.org/network/1142511.WIGMOR_0588Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amin [...]
rnc protein networkhttps://string-db.org/network/1142511.WIGMOR_0589RNase III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, a [...]
lepB protein networkhttps://string-db.org/network/1142511.WIGMOR_0590Leader peptidase (signal peptidase I); Protein involved in serine-type peptidase activity and proteolysis; Belongs to the peptidase S26 family.
lepA protein networkhttps://string-db.org/network/1142511.WIGMOR_0591GTP-binding membrane protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one- [...]
coaE protein networkhttps://string-db.org/network/1142511.WIGMOR_0592dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
AFA41407.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0593Protein involved in transporter activity and transport.
AFA41408.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0594GlnQ family glutamine transport ATP-binding protein; Protein involved in nucleotide binding, nucleoside-triphosphatase activity, ATP binding and ATPase activity.
AFA41409.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0595GltJ family glutamate/aspartate transport system permease protein; Protein involved in transporter activity and transport.
yhdY protein networkhttps://string-db.org/network/1142511.WIGMOR_0596Membrane component of an ABC superfamily predicted amino-acid transporter; Protein involved in transporter activity and transport.
hflC protein networkhttps://string-db.org/network/1142511.WIGMOR_0597Modulator for HflB protease specific for phage lambda cII repressor; HflC and HflK could regulate a protease.
hflK protein networkhttps://string-db.org/network/1142511.WIGMOR_0598Modulator for HflB protease specific for phage lambda cII repressor; HflC and HflK could encode or regulate a protease.
hfq protein networkhttps://string-db.org/network/1142511.WIGMOR_0599RNA-binding protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes i [...]
miaA protein networkhttps://string-db.org/network/1142511.WIGMOR_0600Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, lea [...]
phr protein networkhttps://string-db.org/network/1142511.WIGMOR_0601FAD-binding deoxyribodipyrimidine photolyase; Protein involved in DNA photolyase activity and DNA repair.
ackA protein networkhttps://string-db.org/network/1142511.WIGMOR_0602Acetate kinase A and propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
pta protein networkhttps://string-db.org/network/1142511.WIGMOR_0603Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
purA protein networkhttps://string-db.org/network/1142511.WIGMOR_0604Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
rlmB protein networkhttps://string-db.org/network/1142511.WIGMOR_060523S rRNA (Gm2251)-methyltransferase; Protein involved in RNA methyltransferase activity, methyltransferase activity, RNA binding and RNA processing; Belongs to the class IV-like SAM-binding methy [...]
cspE protein networkhttps://string-db.org/network/1142511.WIGMOR_0606DNA-binding transcriptional repressor; Protein involved in nucleic acid binding, DNA binding and regulation of transcription, DNA-dependent.
lipA protein networkhttps://string-db.org/network/1142511.WIGMOR_0607Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, ther [...]
lipB protein networkhttps://string-db.org/network/1142511.WIGMOR_0608Lipoyl-protein ligase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also [...]
dacA protein networkhttps://string-db.org/network/1142511.WIGMOR_0609D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Protein involved in serine-type D-Ala-D-Ala carboxypeptidase activity, carboxypeptidase activity and proteolysis; Belongs to th [...]
mrdB protein networkhttps://string-db.org/network/1142511.WIGMOR_0610Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
mrdA protein networkhttps://string-db.org/network/1142511.WIGMOR_0611Protein involved in penicillin binding, peptidoglycan biosynthetic process and peptidoglycan-based cell wall biogenesis.
nadD protein networkhttps://string-db.org/network/1142511.WIGMOR_0612NAD(P)-dependent nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
AFA41427.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0613DNA polymerase III delta subunit; Protein involved in DNA binding, DNA-directed DNA polymerase activity and DNA replication.
AFA41428.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0614RlpB family protein; Protein involved in cellular membrane organization and Gram-negative-bacterium-type cell outer membrane assembly.
leuS protein networkhttps://string-db.org/network/1142511.WIGMOR_0615leucyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding, leucine-tRNA ligase activity, tRNA aminoacylation for protein translation and leucyl-t [...]
rsmE protein networkhttps://string-db.org/network/1142511.WIGMOR_061616S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
gshB protein networkhttps://string-db.org/network/1142511.WIGMOR_0617Glutathione synthetase; Protein involved in catalytic activity, ATP binding, ligase activity, glutathione synthase activity and glutathione biosynthetic process; Belongs to the prokaryotic GSH sy [...]
AFA41432.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0618Putative Holliday junction resolvase; Protein involved in hydrolase activity, acting on ester bonds, nucleic acid binding, nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, D [...]
arnT protein networkhttps://string-db.org/network/1142511.WIGMOR_06204-amino-4-deoxy-L-arabinose transferase; Frameshift mutation relative to Escherichia coli K-12 MG1655 (ASAP:ABE-0012623); has termination codon at position 142; GTP-binding protein (pseudogene).
pmrJ protein networkhttps://string-db.org/network/1142511.WIGMOR_0621Putative polymyxin resistance deacetylase; Protein involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, catalytic activity and carbohydrate metabolic process.
arnA protein networkhttps://string-db.org/network/1142511.WIGMOR_0622UDP-L-Ara4N formyltransferase/UDP-GlcA C-4'-decarboxylase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) [...]
arnC protein networkhttps://string-db.org/network/1142511.WIGMOR_0623Undecaprenyl-phosphate 4-amino-4-deoxy-L-arabinose transferase.
nadA protein networkhttps://string-db.org/network/1142511.WIGMOR_0624Quinolinate synthase, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
yajR protein networkhttps://string-db.org/network/1142511.WIGMOR_0625Putative transporter; Protein involved in transmembrane transport.
bolA protein networkhttps://string-db.org/network/1142511.WIGMOR_0626BolA family morphoprotein; Belongs to the BolA/IbaG family.
AFA41440.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0627Cell division trigger factor; Protein involved in protein folding and protein transport.
clpP protein networkhttps://string-db.org/network/1142511.WIGMOR_0628ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
clpX protein networkhttps://string-db.org/network/1142511.WIGMOR_0629ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform cha [...]
lon protein networkhttps://string-db.org/network/1142511.WIGMOR_0630DNA-binding ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. R [...]
AFA41444.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0631PpiD family peptidyl-prolyl cis-trans isomerase; Protein involved in isomerase activity, protein folding and protein transport.
cyoE protein networkhttps://string-db.org/network/1142511.WIGMOR_0632Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
cyoD protein networkhttps://string-db.org/network/1142511.WIGMOR_0633Protein involved in cytochrome o ubiquinol oxidase activity and electron transport coupled proton transport.
cyoC protein networkhttps://string-db.org/network/1142511.WIGMOR_0634Protein involved in cytochrome-c oxidase activity, oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor, respiratory electron transport chain, mitocho [...]
cyoB protein networkhttps://string-db.org/network/1142511.WIGMOR_0635Protein involved in cytochrome-c oxidase activity, oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor, iron ion binding, electron carrier activity, [...]
cyoA protein networkhttps://string-db.org/network/1142511.WIGMOR_0636Protein involved in cytochrome-c oxidase activity, copper ion binding, electron carrier activity, heme binding, oxidoreductase activity, acting on diphenols and related substances as donors, oxyg [...]
panE protein networkhttps://string-db.org/network/1142511.WIGMOR_0637NADPH-specific 2-dehydropantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
ispA protein networkhttps://string-db.org/network/1142511.WIGMOR_0639Geranyltranstransferase; N-terminal deletion relative to Escherichia coli K-12 MG1655 (ASAP:ABE-0001470); sulfur transfer protein (pseudogene); Belongs to the FPP/GGPP synthase family.
dxs protein networkhttps://string-db.org/network/1142511.WIGMOR_06401-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP) [...]
degQ protein networkhttps://string-db.org/network/1142511.WIGMOR_0641Serine endoprotease; Protein involved in catalytic activity, protein binding, serine-type endopeptidase activity and proteolysis; Belongs to the peptidase S1C family.
AFA41454.1 protein networkhttps://string-db.org/network/1142511.WIGMOR_0642Putative membrane protein.
yhcM protein networkhttps://string-db.org/network/1142511.WIGMOR_0643Putative nucleoside triphosphate hydrolase; Protein involved in ATP binding.
rplM protein networkhttps://string-db.org/network/1142511.WIGMOR_064450S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the earl [...]
rpsI protein networkhttps://string-db.org/network/1142511.WIGMOR_064530S ribosomal subunit protein S9; Protein involved in structural constituent of ribosome and translation; Belongs to the universal ribosomal protein uS9 family.
tadA protein networkhttps://string-db.org/network/1142511.WIGMOR_0646tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
purL protein networkhttps://string-db.org/network/1142511.WIGMOR_0647Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide [...]
pykA protein networkhttps://string-db.org/network/1142511.WIGMOR_0648Pyruvate kinase II; Protein involved in catalytic activity, pyruvate kinase activity, magnesium ion binding, potassium ion binding and glycolysis; Belongs to the pyruvate kinase family.
pitA protein networkhttps://string-db.org/network/1142511.WIGMOR_0649Phosphate transporter, low-affinity; Protein involved in inorganic phosphate transmembrane transporter activity and phosphate transport.
murI protein networkhttps://string-db.org/network/1142511.WIGMOR_0651Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
hemB protein networkhttps://string-db.org/network/1142511.WIGMOR_0653Porphobilinogen synthase; Protein involved in catalytic activity, porphobilinogen synthase activity, metal ion binding, metabolic process and tetrapyrrole biosynthetic process; Belongs to the ALA [...]
pyrD protein networkhttps://string-db.org/network/1142511.WIGMOR_0654Dihydro-orotate oxidase, FMN-linked; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
yceN protein networkhttps://string-db.org/network/1142511.WIGMOR_0655Putative inner membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
argS protein networkhttps://string-db.org/network/1142511.WIGMOR_0656arginyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding, arginine-tRNA ligase activity, tRNA aminoacylation for protein translation and arginy [...]
plsB protein networkhttps://string-db.org/network/1142511.WIGMOR_0657Protein involved in acyltransferase activity, glycerol-3-phosphate O-acyltransferase activity, metabolic process, phospholipid biosynthetic process and cellular lipid metabolic process; Belongs t [...]
ubiA protein networkhttps://string-db.org/network/1142511.WIGMOR_0658P-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubi [...]
rplY protein networkhttps://string-db.org/network/1142511.WIGMOR_065950S ribosomal subunit protein L25; Protein involved in structural constituent of ribosome, 5S rRNA binding and translation; Belongs to the bacterial ribosomal protein bL25 family.
gltX protein networkhttps://string-db.org/network/1142511.WIGMOR_0661glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
ycbL protein networkhttps://string-db.org/network/1142511.WIGMOR_0663Putative metal-binding enzyme; Protein involved in hydrolase activity.
aspC protein networkhttps://string-db.org/network/1142511.WIGMOR_0664Aspartate transaminase; Protein involved in catalytic activity, pyridoxal phosphate binding, transferase activity, transferring nitrogenous groups, transaminase activity, biosynthetic process and [...]
mqo protein networkhttps://string-db.org/network/1142511.WIGMOR_0671Protein involved in malate dehydrogenase (quinone) activity, tricarboxylic acid cycle and oxidation-reduction process.
guaB protein networkhttps://string-db.org/network/1142511.WIGMOR_0672IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleoti [...]
guaA protein networkhttps://string-db.org/network/1142511.WIGMOR_0673GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP.
yicC protein networkhttps://string-db.org/network/1142511.WIGMOR_0674YicC family protein.
trkD protein networkhttps://string-db.org/network/1142511.WIGMOR_0675Potassium transporter; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system); Belongs to the HAK/KUP transporter [...]
nrdF protein networkhttps://string-db.org/network/1142511.WIGMOR_0676Ferritin-like ribonucleoside-diphosphate reductase 2, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding [...]
nrdE protein networkhttps://string-db.org/network/1142511.WIGMOR_0677Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotid [...]
nrdI protein networkhttps://string-db.org/network/1142511.WIGMOR_0678NrdI family ribonucleotide reduction protein; Probably involved in ribonucleotide reductase function.