Organism Overview: Buchnera aphidicola Ua


 
mnmG protein networkhttps://string-db.org/network/1005057.BUAMB_001tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
atpB protein networkhttps://string-db.org/network/1005057.BUAMB_002F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.
atpE protein networkhttps://string-db.org/network/1005057.BUAMB_003F0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extr [...]
atpF protein networkhttps://string-db.org/network/1005057.BUAMB_004F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
atpH protein networkhttps://string-db.org/network/1005057.BUAMB_005F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the [...]
atpA protein networkhttps://string-db.org/network/1005057.BUAMB_006F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
atpG protein networkhttps://string-db.org/network/1005057.BUAMB_007F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the [...]
atpD protein networkhttps://string-db.org/network/1005057.BUAMB_008F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
atpC protein networkhttps://string-db.org/network/1005057.BUAMB_009F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.
gyrB protein networkhttps://string-db.org/network/1005057.BUAMB_010DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
dnaN protein networkhttps://string-db.org/network/1005057.BUAMB_011DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading [...]
dnaA protein networkhttps://string-db.org/network/1005057.BUAMB_012Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-s [...]
rpmH protein networkhttps://string-db.org/network/1005057.BUAMB_01350S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
rnpA protein networkhttps://string-db.org/network/1005057.BUAMB_014Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]
yidC protein networkhttps://string-db.org/network/1005057.BUAMB_01560 kDa inner-membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane prote [...]
mnmE protein networkhttps://string-db.org/network/1005057.BUAMB_016tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
groES protein networkhttps://string-db.org/network/1005057.BUAMB_018Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
groEL protein networkhttps://string-db.org/network/1005057.BUAMB_019Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
efp protein networkhttps://string-db.org/network/1005057.BUAMB_020Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by [...]
dnaC protein networkhttps://string-db.org/network/1005057.BUAMB_021DNA replication protein DnaC.
dnaT protein networkhttps://string-db.org/network/1005057.BUAMB_022Primosomal protein DnaI; This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert [...]
rsmD protein networkhttps://string-db.org/network/1005057.BUAMB_02316S rRNA m2G966 methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
ftsY protein networkhttps://string-db.org/network/1005057.BUAMB_024Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition par [...]
rpoH protein networkhttps://string-db.org/network/1005057.BUAMB_025RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involve [...]
glmS protein networkhttps://string-db.org/network/1005057.BUAMB_026Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
glmU protein networkhttps://string-db.org/network/1005057.BUAMB_027UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyz [...]
yigL protein networkhttps://string-db.org/network/1005057.BUAMB_028Sugar phosphatase; Fusion of APS loci BU028/BU029.
metE protein networkhttps://string-db.org/network/1005057.BUAMB_0295-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation [...]
purH protein networkhttps://string-db.org/network/1005057.BUAMB_030Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.
hupA protein networkhttps://string-db.org/network/1005057.BUAMB_031DNA-binding protein HU-alpha; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
rpoC protein networkhttps://string-db.org/network/1005057.BUAMB_032DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/1005057.BUAMB_033DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/1005057.BUAMB_03450S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the ba [...]
rplJ protein networkhttps://string-db.org/network/1005057.BUAMB_03550S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
rplA protein networkhttps://string-db.org/network/1005057.BUAMB_03650S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/1005057.BUAMB_03750S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/1005057.BUAMB_038Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the [...]
secE protein networkhttps://string-db.org/network/1005057.BUAMB_039Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Be [...]
murB protein networkhttps://string-db.org/network/1005057.BUAMB_044UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
metF protein networkhttps://string-db.org/network/1005057.BUAMB_0455,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
argG protein networkhttps://string-db.org/network/1005057.BUAMB_046Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
argH protein networkhttps://string-db.org/network/1005057.BUAMB_047Argininosuccinate lyase.
yibN protein networkhttps://string-db.org/network/1005057.BUAMB_048Putative rhodanese-related sulfurtransferase.
secB protein networkhttps://string-db.org/network/1005057.BUAMB_049Preprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor p [...]
cysE protein networkhttps://string-db.org/network/1005057.BUAMB_050Serine acetyltransferase.
rpoD protein networkhttps://string-db.org/network/1005057.BUAMB_051RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the p [...]
dnaG protein networkhttps://string-db.org/network/1005057.BUAMB_052DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpsU protein networkhttps://string-db.org/network/1005057.BUAMB_05330S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
ygjD protein networkhttps://string-db.org/network/1005057.BUAMB_054Putative DNA-binding/iron metalloprotein/AP endonuclease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with ad [...]
ribB protein networkhttps://string-db.org/network/1005057.BUAMB_0553,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
rfaE protein networkhttps://string-db.org/network/1005057.BUAMB_056Kinase.
cca protein networkhttps://string-db.org/network/1005057.BUAMB_057tRNA CCA-pyrophosphorylase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order [...]
bacA protein networkhttps://string-db.org/network/1005057.BUAMB_058Bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
crr protein networkhttps://string-db.org/network/1005057.BUAMB_059Glucose-specific PTS system component.
ptsI protein networkhttps://string-db.org/network/1005057.BUAMB_060Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate ac [...]
ptsH protein networkhttps://string-db.org/network/1005057.BUAMB_061Phosphocarrier protein HPr.
cysK protein networkhttps://string-db.org/network/1005057.BUAMB_062Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
lig protein networkhttps://string-db.org/network/1005057.BUAMB_063DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energ [...]
gltX protein networkhttps://string-db.org/network/1005057.BUAMB_066glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
fliE protein networkhttps://string-db.org/network/1005057.BUAMB_068Flagellar hook-basal body complex protein FliE.
fliF protein networkhttps://string-db.org/network/1005057.BUAMB_069Flagellar MS-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
fliG protein networkhttps://string-db.org/network/1005057.BUAMB_070Flagellar motor switch protein FliG.
fliH protein networkhttps://string-db.org/network/1005057.BUAMB_071Flagellar assembly protein FliH.
fliI protein networkhttps://string-db.org/network/1005057.BUAMB_072Flagellum-specific ATP synthase; APS ortholog longer than E. coli.
fliJ protein networkhttps://string-db.org/network/1005057.BUAMB_073Flagellar FliJ protein.
fliK protein networkhttps://string-db.org/network/1005057.BUAMB_074Flagellar hook-length control protein; Fusion of APS loci BU078/BU079; fused in Sg, 5A.
fliM protein networkhttps://string-db.org/network/1005057.BUAMB_075Flagellar motor switch protein FliM.
fliN protein networkhttps://string-db.org/network/1005057.BUAMB_076Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex inte [...]
fliP protein networkhttps://string-db.org/network/1005057.BUAMB_077Type III secretion system protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
fliQ protein networkhttps://string-db.org/network/1005057.BUAMB_078Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.
fliR protein networkhttps://string-db.org/network/1005057.BUAMB_079Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.
rpmG protein networkhttps://string-db.org/network/1005057.BUAMB_08050S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/1005057.BUAMB_08150S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
ytfN protein networkhttps://string-db.org/network/1005057.BUAMB_082Conserved protein.
ppa protein networkhttps://string-db.org/network/1005057.BUAMB_083Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
pmbA protein networkhttps://string-db.org/network/1005057.BUAMB_084PmbA protein.
rsmI protein networkhttps://string-db.org/network/1005057.BUAMB_08616S rRNA 2'-O-ribose C1402 methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
fabB protein networkhttps://string-db.org/network/1005057.BUAMB_0873-oxoacyl-[acyl-carrier-protein] synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
talA protein networkhttps://string-db.org/network/1005057.BUAMB_088Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
tktB protein networkhttps://string-db.org/network/1005057.BUAMB_089Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
dapE protein networkhttps://string-db.org/network/1005057.BUAMB_090Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in [...]
dapA protein networkhttps://string-db.org/network/1005057.BUAMB_091Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
aroC protein networkhttps://string-db.org/network/1005057.BUAMB_092Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
yfcN protein networkhttps://string-db.org/network/1005057.BUAMB_093Conserved protein; C terminal truncation (8AA); Belongs to the UPF0115 family.
hisG protein networkhttps://string-db.org/network/1005057.BUAMB_094ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
hisD protein networkhttps://string-db.org/network/1005057.BUAMB_095Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisC protein networkhttps://string-db.org/network/1005057.BUAMB_096Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
hisB protein networkhttps://string-db.org/network/1005057.BUAMB_097Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; In the N-terminal section; belongs to the histidinol- phosphatase family.
hisH protein networkhttps://string-db.org/network/1005057.BUAMB_098Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glu [...]
hisA protein networkhttps://string-db.org/network/1005057.BUAMB_0991-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
hisF protein networkhttps://string-db.org/network/1005057.BUAMB_100Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that prod [...]
hisI protein networkhttps://string-db.org/network/1005057.BUAMB_101Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.
gnd protein networkhttps://string-db.org/network/1005057.BUAMB_1026-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
dcd protein networkhttps://string-db.org/network/1005057.BUAMB_103Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
metG protein networkhttps://string-db.org/network/1005057.BUAMB_104methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
tilS protein networkhttps://string-db.org/network/1005057.BUAMB_105Cell cycle protein MesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is conve [...]
ribC protein networkhttps://string-db.org/network/1005057.BUAMB_107Riboflavin synthase subunit alpha.
nth protein networkhttps://string-db.org/network/1005057.BUAMB_108Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- [...]
priA protein networkhttps://string-db.org/network/1005057.BUAMB_109Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its h [...]
tyrS protein networkhttps://string-db.org/network/1005057.BUAMB_110tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
sufA protein networkhttps://string-db.org/network/1005057.BUAMB_111Fe-S cluster assembly, scaffold protein; Belongs to the HesB/IscA family.
ydiK protein networkhttps://string-db.org/network/1005057.BUAMB_112Putative inner membrane protein.
aroH protein networkhttps://string-db.org/network/1005057.BUAMB_113Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate [...]
thrS protein networkhttps://string-db.org/network/1005057.BUAMB_114threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
infC protein networkhttps://string-db.org/network/1005057.BUAMB_115Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
rpmI protein networkhttps://string-db.org/network/1005057.BUAMB_11650S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
rplT protein networkhttps://string-db.org/network/1005057.BUAMB_11750S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
pheS protein networkhttps://string-db.org/network/1005057.BUAMB_118phenylalanyl-tRNA synthetase subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
pheT protein networkhttps://string-db.org/network/1005057.BUAMB_119phenylalanyl-tRNA synthetase subunit beta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
ihfA protein networkhttps://string-db.org/network/1005057.BUAMB_120Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tra [...]
tgt protein networkhttps://string-db.org/network/1005057.BUAMB_121Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in [...]
yajC protein networkhttps://string-db.org/network/1005057.BUAMB_122Hypothetical protein; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and asse [...]
glyS protein networkhttps://string-db.org/network/1005057.BUAMB_123glycyl-tRNA synthetase beta chain.
glyQ protein networkhttps://string-db.org/network/1005057.BUAMB_124glycyl-tRNA synthetase subunit alpha.
nfo protein networkhttps://string-db.org/network/1005057.BUAMB_125Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-p [...]
rplY protein networkhttps://string-db.org/network/1005057.BUAMB_12650S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
yabI protein networkhttps://string-db.org/network/1005057.BUAMB_127Conserved inner membrane protein.
surA protein networkhttps://string-db.org/network/1005057.BUAMB_128Survival protein SurA precursor.
rsmA protein networkhttps://string-db.org/network/1005057.BUAMB_129Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
apaH protein networkhttps://string-db.org/network/1005057.BUAMB_130Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
folA protein networkhttps://string-db.org/network/1005057.BUAMB_131Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
carB protein networkhttps://string-db.org/network/1005057.BUAMB_132Carbamoyl phosphate synthase large subunit; Belongs to the CarB family.
carA protein networkhttps://string-db.org/network/1005057.BUAMB_133Carbamoyl phosphate synthase small subunit; Belongs to the CarA family.
dapB protein networkhttps://string-db.org/network/1005057.BUAMB_134Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
ispH protein networkhttps://string-db.org/network/1005057.BUAMB_1354-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethyl [...]
lspA protein networkhttps://string-db.org/network/1005057.BUAMB_136Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
ileS protein networkhttps://string-db.org/network/1005057.BUAMB_137isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
rpsT protein networkhttps://string-db.org/network/1005057.BUAMB_13930S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
dnaJ protein networkhttps://string-db.org/network/1005057.BUAMB_140DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous [...]
dnaK protein networkhttps://string-db.org/network/1005057.BUAMB_141Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
nuoA protein networkhttps://string-db.org/network/1005057.BUAMB_142NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoB protein networkhttps://string-db.org/network/1005057.BUAMB_143NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoCD protein networkhttps://string-db.org/network/1005057.BUAMB_144Bifunctional NADH:ubiquinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron a [...]
nuoE protein networkhttps://string-db.org/network/1005057.BUAMB_145NADH dehydrogenase subunit E.
nuoF protein networkhttps://string-db.org/network/1005057.BUAMB_146NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
nuoG protein networkhttps://string-db.org/network/1005057.BUAMB_147NADH dehydrogenase subunit G.
nuoH protein networkhttps://string-db.org/network/1005057.BUAMB_148NADH dehydrogenase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoI protein networkhttps://string-db.org/network/1005057.BUAMB_149NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoJ protein networkhttps://string-db.org/network/1005057.BUAMB_150NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation [...]
nuoK protein networkhttps://string-db.org/network/1005057.BUAMB_151NADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoL protein networkhttps://string-db.org/network/1005057.BUAMB_152NADH dehydrogenase I chain L.
nuoM protein networkhttps://string-db.org/network/1005057.BUAMB_153NADH dehydrogenase I chain M.
nuoN protein networkhttps://string-db.org/network/1005057.BUAMB_154NADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
folC protein networkhttps://string-db.org/network/1005057.BUAMB_155Dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2 [...]
cvpA protein networkhttps://string-db.org/network/1005057.BUAMB_156Colicin V production protein.
prs protein networkhttps://string-db.org/network/1005057.BUAMB_157Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
ispE protein networkhttps://string-db.org/network/1005057.BUAMB_1584-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. I [...]
prfA protein networkhttps://string-db.org/network/1005057.BUAMB_159Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
prmC protein networkhttps://string-db.org/network/1005057.BUAMB_160HemK protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-gluta [...]
ychA protein networkhttps://string-db.org/network/1005057.BUAMB_161Putative transcriptional regulator.
nadE protein networkhttps://string-db.org/network/1005057.BUAMB_162NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
ackA protein networkhttps://string-db.org/network/1005057.BUAMB_163Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
pta protein networkhttps://string-db.org/network/1005057.BUAMB_164Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
yfaE protein networkhttps://string-db.org/network/1005057.BUAMB_1652Fe-2S cluster-containing protein involved in diferric-tyrosyl radical cofactor maintenance.
nrdB protein networkhttps://string-db.org/network/1005057.BUAMB_166Ribonucleotide-diphosphate reductase subunit beta.
nrdA protein networkhttps://string-db.org/network/1005057.BUAMB_167Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
gyrA protein networkhttps://string-db.org/network/1005057.BUAMB_168DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
yba2 protein networkhttps://string-db.org/network/1005057.BUAMB_169Hypothetical protein.
ahpC protein networkhttps://string-db.org/network/1005057.BUAMB_170Alkyl hydroperoxide reductase.
ung protein networkhttps://string-db.org/network/1005057.BUAMB_171uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
grpE protein networkhttps://string-db.org/network/1005057.BUAMB_172Heat shock protein GrpE2; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is [...]
nadK protein networkhttps://string-db.org/network/1005057.BUAMB_173Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosph [...]
grxD protein networkhttps://string-db.org/network/1005057.BUAMB_175Glutaredoxin 4; Belongs to the glutaredoxin family. Monothiol subfamily.
rnt protein networkhttps://string-db.org/network/1005057.BUAMB_176Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP [...]
sodA protein networkhttps://string-db.org/network/1005057.BUAMB_177Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
pth protein networkhttps://string-db.org/network/1005057.BUAMB_178peptidyl-tRNA hydrolase.
ychF protein networkhttps://string-db.org/network/1005057.BUAMB_179GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
thrC protein networkhttps://string-db.org/network/1005057.BUAMB_180Threonine synthase.
thrB protein networkhttps://string-db.org/network/1005057.BUAMB_181Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
thrA protein networkhttps://string-db.org/network/1005057.BUAMB_182Bifunctional aspartokinase I/homoserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family.
hpt protein networkhttps://string-db.org/network/1005057.BUAMB_183Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
dksA protein networkhttps://string-db.org/network/1005057.BUAMB_184DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several am [...]
truA protein networkhttps://string-db.org/network/1005057.BUAMB_185tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
mrcB protein networkhttps://string-db.org/network/1005057.BUAMB_186Penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domai [...]
secA protein networkhttps://string-db.org/network/1005057.BUAMB_187Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to [...]
coaE protein networkhttps://string-db.org/network/1005057.BUAMB_188dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
guaC protein networkhttps://string-db.org/network/1005057.BUAMB_189Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivative [...]
aceE protein networkhttps://string-db.org/network/1005057.BUAMB_190Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
aceF protein networkhttps://string-db.org/network/1005057.BUAMB_191Branched-chain alpha-keto acid dehydrogenase subunit E2.
lpdA protein networkhttps://string-db.org/network/1005057.BUAMB_192Dihydrolipoamide dehydrogenase.
mtn protein networkhttps://string-db.org/network/1005057.BUAMB_1935'-methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the cor [...]
erpA protein networkhttps://string-db.org/network/1005057.BUAMB_194Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG.
ftsZ protein networkhttps://string-db.org/network/1005057.BUAMB_195Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
ftsA protein networkhttps://string-db.org/network/1005057.BUAMB_196Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
ddl protein networkhttps://string-db.org/network/1005057.BUAMB_197D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
murC protein networkhttps://string-db.org/network/1005057.BUAMB_198UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
murG protein networkhttps://string-db.org/network/1005057.BUAMB_199Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptid [...]
ftsW protein networkhttps://string-db.org/network/1005057.BUAMB_200Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
murD protein networkhttps://string-db.org/network/1005057.BUAMB_201UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF f [...]
mraY protein networkhttps://string-db.org/network/1005057.BUAMB_202phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...]
murE protein networkhttps://string-db.org/network/1005057.BUAMB_204UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) [...]
ftsI protein networkhttps://string-db.org/network/1005057.BUAMB_205Cell division protein FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
ftsL protein networkhttps://string-db.org/network/1005057.BUAMB_206Cell division protein.
rsmH protein networkhttps://string-db.org/network/1005057.BUAMB_20716S rRNA m4C1402 methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ilvH protein networkhttps://string-db.org/network/1005057.BUAMB_208Acetolactate synthase small subunit.
ilvI protein networkhttps://string-db.org/network/1005057.BUAMB_209Acetolactate synthase large subunit.
degP protein networkhttps://string-db.org/network/1005057.BUAMB_210Serine endoprotease; Belongs to the peptidase S1C family.
dapD protein networkhttps://string-db.org/network/1005057.BUAMB_2112,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
map protein networkhttps://string-db.org/network/1005057.BUAMB_212Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
rpsB protein networkhttps://string-db.org/network/1005057.BUAMB_21330S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/1005057.BUAMB_214Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
pyrH protein networkhttps://string-db.org/network/1005057.BUAMB_215Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
frr protein networkhttps://string-db.org/network/1005057.BUAMB_216Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
dxr protein networkhttps://string-db.org/network/1005057.BUAMB_2171-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).
ispU protein networkhttps://string-db.org/network/1005057.BUAMB_218Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,3 [...]
bamA protein networkhttps://string-db.org/network/1005057.BUAMB_219Outer membrane associated protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, w [...]
fabZ protein networkhttps://string-db.org/network/1005057.BUAMB_2203-hydroxy-acyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and un [...]
dnaE protein networkhttps://string-db.org/network/1005057.BUAMB_221DNA polymerase III alpha chain.
proS protein networkhttps://string-db.org/network/1005057.BUAMB_222prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
flhB protein networkhttps://string-db.org/network/1005057.BUAMB_223Flagellar biosynthesis protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of [...]
flhA protein networkhttps://string-db.org/network/1005057.BUAMB_224Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs [...]
argS protein networkhttps://string-db.org/network/1005057.BUAMB_225arginyl-tRNA synthetase.
gloB protein networkhttps://string-db.org/network/1005057.BUAMB_229Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
rnhA protein networkhttps://string-db.org/network/1005057.BUAMB_230Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family.
dnaQ protein networkhttps://string-db.org/network/1005057.BUAMB_231DNA polymerase III epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing functio [...]
lpcA protein networkhttps://string-db.org/network/1005057.BUAMB_233Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
gpt protein networkhttps://string-db.org/network/1005057.BUAMB_234Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
grpE1 protein networkhttps://string-db.org/network/1005057.BUAMB_235Heat shock protein GrpE1; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is [...]
smpB protein networkhttps://string-db.org/network/1005057.BUAMB_236SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
tadA protein networkhttps://string-db.org/network/1005057.BUAMB_237tRNA-specific adenosine deaminase monomer; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
acpS protein networkhttps://string-db.org/network/1005057.BUAMB_238Holo-[acyl-carrier protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
era protein networkhttps://string-db.org/network/1005057.BUAMB_239GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly als [...]
rnc protein networkhttps://string-db.org/network/1005057.BUAMB_240Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
lepB protein networkhttps://string-db.org/network/1005057.BUAMB_241Signal peptidase I; Belongs to the peptidase S26 family.
lepA protein networkhttps://string-db.org/network/1005057.BUAMB_242GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
mnmA protein networkhttps://string-db.org/network/1005057.BUAMB_243tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step o [...]
purB protein networkhttps://string-db.org/network/1005057.BUAMB_245Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
emtA protein networkhttps://string-db.org/network/1005057.BUAMB_246Membrane-bound lytic murein transglycosylase E; N terminal truncation (25AA).
fabI protein networkhttps://string-db.org/network/1005057.BUAMB_247Enoyl-[acyl-carrier-protein] reductase (NADH).
rnb protein networkhttps://string-db.org/network/1005057.BUAMB_248Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
ychE protein networkhttps://string-db.org/network/1005057.BUAMB_249Putative inner membrane protein.
lipB protein networkhttps://string-db.org/network/1005057.BUAMB_250Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act [...]
lipA protein networkhttps://string-db.org/network/1005057.BUAMB_251Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, there [...]
pyrF protein networkhttps://string-db.org/network/1005057.BUAMB_252Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamil [...]
ribA protein networkhttps://string-db.org/network/1005057.BUAMB_253GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
cls protein networkhttps://string-db.org/network/1005057.BUAMB_254Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
yciA protein networkhttps://string-db.org/network/1005057.BUAMB_255acyl-CoA thioesterase.
yciB protein networkhttps://string-db.org/network/1005057.BUAMB_256Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
yciC protein networkhttps://string-db.org/network/1005057.BUAMB_257Putative inner membrane protein.
trpA protein networkhttps://string-db.org/network/1005057.BUAMB_258Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
trpB protein networkhttps://string-db.org/network/1005057.BUAMB_259Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpC protein networkhttps://string-db.org/network/1005057.BUAMB_260Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Belongs to the TrpC family.
trpD protein networkhttps://string-db.org/network/1005057.BUAMB_261Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranila [...]
yedA protein networkhttps://string-db.org/network/1005057.BUAMB_262Putative membrane transport protein.
rluB protein networkhttps://string-db.org/network/1005057.BUAMB_26323S rRNA pseudouridine 2605 synthase; Belongs to the pseudouridine synthase RsuA family.
sohB protein networkhttps://string-db.org/network/1005057.BUAMB_264Putative periplasmic protease.
topA protein networkhttps://string-db.org/network/1005057.BUAMB_265DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of [...]
suhB protein networkhttps://string-db.org/network/1005057.BUAMB_266Extragenic suppressor protein SuhB; Belongs to the inositol monophosphatase superfamily.
rlmN protein networkhttps://string-db.org/network/1005057.BUAMB_26723S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the [...]
ispG protein networkhttps://string-db.org/network/1005057.BUAMB_2684-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG fa [...]
hisS protein networkhttps://string-db.org/network/1005057.BUAMB_269histidyl-tRNA synthetase.
glyA protein networkhttps://string-db.org/network/1005057.BUAMB_270Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
bioD protein networkhttps://string-db.org/network/1005057.BUAMB_271Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ur [...]
bioB protein networkhttps://string-db.org/network/1005057.BUAMB_272Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfami [...]
bioA protein networkhttps://string-db.org/network/1005057.BUAMB_273Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8 [...]
pgl protein networkhttps://string-db.org/network/1005057.BUAMB_2746-phosphogluconolactonase.
mfd protein networkhttps://string-db.org/network/1005057.BUAMB_275Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated tr [...]
lolC protein networkhttps://string-db.org/network/1005057.BUAMB_276Membrane component of lipoprotein export ABC transporter.
lolD protein networkhttps://string-db.org/network/1005057.BUAMB_277ABC transporter ATP-binding protein of lipoprotein export ABC transporter; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
gapA protein networkhttps://string-db.org/network/1005057.BUAMB_279Glyceraldehyde 3-phosphate dehydrogenase A; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
fldA protein networkhttps://string-db.org/network/1005057.BUAMB_280Flavodoxin FldA; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
phr protein networkhttps://string-db.org/network/1005057.BUAMB_281Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family.
ybgI protein networkhttps://string-db.org/network/1005057.BUAMB_282Conserved metal-binding protein.
sucA protein networkhttps://string-db.org/network/1005057.BUAMB_2832-oxoglutarate dehydrogenase E1 component.
sucB protein networkhttps://string-db.org/network/1005057.BUAMB_2842-oxoglutarate dehydrogenase E2 component.
gpmA protein networkhttps://string-db.org/network/1005057.BUAMB_285Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
pfkA protein networkhttps://string-db.org/network/1005057.BUAMB_2866-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
glpF protein networkhttps://string-db.org/network/1005057.BUAMB_287Glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
tpiA protein networkhttps://string-db.org/network/1005057.BUAMB_288Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
ihfB protein networkhttps://string-db.org/network/1005057.BUAMB_289Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tran [...]
rpsA protein networkhttps://string-db.org/network/1005057.BUAMB_29030S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
aroA protein networkhttps://string-db.org/network/1005057.BUAMB_2913-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
serC protein networkhttps://string-db.org/network/1005057.BUAMB_292Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belon [...]
serS protein networkhttps://string-db.org/network/1005057.BUAMB_293seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
trxB protein networkhttps://string-db.org/network/1005057.BUAMB_294Thioredoxin reductase.
infA protein networkhttps://string-db.org/network/1005057.BUAMB_295Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
aspS protein networkhttps://string-db.org/network/1005057.BUAMB_296aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
znuB protein networkhttps://string-db.org/network/1005057.BUAMB_297High-affinity zinc uptake system membrane protein ZnuB.
znuC protein networkhttps://string-db.org/network/1005057.BUAMB_298High-affinity zinc uptake system ATP-binding protein ZnuC; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to [...]
pykA protein networkhttps://string-db.org/network/1005057.BUAMB_299Pyruvate kinase; Belongs to the pyruvate kinase family.
zwf protein networkhttps://string-db.org/network/1005057.BUAMB_300Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
htpX protein networkhttps://string-db.org/network/1005057.BUAMB_301Heat shock protein HtpX; Belongs to the peptidase M48B family.
cspC protein networkhttps://string-db.org/network/1005057.BUAMB_302Cold shock-like protein CspC.
yoaE protein networkhttps://string-db.org/network/1005057.BUAMB_303Putative inner membrane protein.
minE protein networkhttps://string-db.org/network/1005057.BUAMB_305Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensu [...]
minD protein networkhttps://string-db.org/network/1005057.BUAMB_306Septum site-determining protein MinD.
minC protein networkhttps://string-db.org/network/1005057.BUAMB_307Cell division inhibitor MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have f [...]
rsmC protein networkhttps://string-db.org/network/1005057.BUAMB_30816S rRNA m2G1207 methyltransferas; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.
ompA protein networkhttps://string-db.org/network/1005057.BUAMB_312Outer membrane protein A precursor; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
murJ protein networkhttps://string-db.org/network/1005057.BUAMB_313Virulence factor MviN-like protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
flgN protein networkhttps://string-db.org/network/1005057.BUAMB_314Flagella synthesis protein FlgN.
flgA protein networkhttps://string-db.org/network/1005057.BUAMB_315Flagella basal-body P-ring formation protein FlgA precursor; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for [...]
flgB protein networkhttps://string-db.org/network/1005057.BUAMB_316Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
flgC protein networkhttps://string-db.org/network/1005057.BUAMB_317Flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family.
flgD protein networkhttps://string-db.org/network/1005057.BUAMB_318Basal-body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
flgE protein networkhttps://string-db.org/network/1005057.BUAMB_319Flagellar hook protein FlgE.
flgF protein networkhttps://string-db.org/network/1005057.BUAMB_320Flagellar basal body rod protein FlgF.
flgG protein networkhttps://string-db.org/network/1005057.BUAMB_321Flagellar basal body rod protein FlgG; Belongs to the flagella basal body rod proteins family.
flgH protein networkhttps://string-db.org/network/1005057.BUAMB_322Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
flgI protein networkhttps://string-db.org/network/1005057.BUAMB_323Flagellar basal body P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
flgJ protein networkhttps://string-db.org/network/1005057.BUAMB_324Flagellar protein FlgJ.
flgK protein networkhttps://string-db.org/network/1005057.BUAMB_325Flagellar hook-associated protein 1.
rne protein networkhttps://string-db.org/network/1005057.BUAMB_326Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation [...]
rluC protein networkhttps://string-db.org/network/1005057.BUAMB_327Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
rpmF protein networkhttps://string-db.org/network/1005057.BUAMB_32850S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
fabG protein networkhttps://string-db.org/network/1005057.BUAMB_3303-oxoacyl-[acyl-carrier protein] reductase.
acpP protein networkhttps://string-db.org/network/1005057.BUAMB_331Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
tmk protein networkhttps://string-db.org/network/1005057.BUAMB_332Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
holB protein networkhttps://string-db.org/network/1005057.BUAMB_333DNA polymerase III delta' subunit; N terminal truncation (38AA); 11A homopolymer, 1 bp deletion.
ycfH protein networkhttps://string-db.org/network/1005057.BUAMB_334Putative metallodependent hydrolase.
ptsG protein networkhttps://string-db.org/network/1005057.BUAMB_335Glucose-specific PTS system IIBC components.
hinT protein networkhttps://string-db.org/network/1005057.BUAMB_336Purine nucleoside phosphoramidase.
ycfM protein networkhttps://string-db.org/network/1005057.BUAMB_337Outer membrane lipoprotein - activator of PBP1B activity.
ompF protein networkhttps://string-db.org/network/1005057.BUAMB_338OmpF-like porin.
asnC protein networkhttps://string-db.org/network/1005057.BUAMB_339asparaginyl-tRNA synthetase.
pncB protein networkhttps://string-db.org/network/1005057.BUAMB_340Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase [...]
rlmL protein networkhttps://string-db.org/network/1005057.BUAMB_34123S rRNA m(2)G2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase super [...]
uup protein networkhttps://string-db.org/network/1005057.BUAMB_342ABC transporter ATP-binding protein Uup.
yceA protein networkhttps://string-db.org/network/1005057.BUAMB_343Conserved protein; Belongs to the UPF0176 family.
valS protein networkhttps://string-db.org/network/1005057.BUAMB_344valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
pepA protein networkhttps://string-db.org/network/1005057.BUAMB_345Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
argF protein networkhttps://string-db.org/network/1005057.BUAMB_346Ornithine carbamoyltransferase subunit I; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
tdcF protein networkhttps://string-db.org/network/1005057.BUAMB_347Putative L-PSP (mRNA) endoribonuclease.
deaD protein networkhttps://string-db.org/network/1005057.BUAMB_348ATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
pnp protein networkhttps://string-db.org/network/1005057.BUAMB_349Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
rpsO protein networkhttps://string-db.org/network/1005057.BUAMB_35030S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
truB protein networkhttps://string-db.org/network/1005057.BUAMB_351tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
rbfA protein networkhttps://string-db.org/network/1005057.BUAMB_352Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
infB protein networkhttps://string-db.org/network/1005057.BUAMB_353Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
nusA protein networkhttps://string-db.org/network/1005057.BUAMB_354Transcription elongation factor NusA; Participates in both transcription termination and antitermination.
secG protein networkhttps://string-db.org/network/1005057.BUAMB_356Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
glmM protein networkhttps://string-db.org/network/1005057.BUAMB_357MrsA protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
ftsH protein networkhttps://string-db.org/network/1005057.BUAMB_358Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [...]
rlmE protein networkhttps://string-db.org/network/1005057.BUAMB_359Cell division protein FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
greA protein networkhttps://string-db.org/network/1005057.BUAMB_360Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
yrbA protein networkhttps://string-db.org/network/1005057.BUAMB_361Putative DNA-binding transcriptional regulator; Belongs to the BolA/IbaG family.
murA protein networkhttps://string-db.org/network/1005057.BUAMB_362UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
rplU protein networkhttps://string-db.org/network/1005057.BUAMB_36350S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
rpmA protein networkhttps://string-db.org/network/1005057.BUAMB_36450S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
obgE protein networkhttps://string-db.org/network/1005057.BUAMB_365GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in contr [...]
rpsI protein networkhttps://string-db.org/network/1005057.BUAMB_36630S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
rplM protein networkhttps://string-db.org/network/1005057.BUAMB_36750S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
pheA protein networkhttps://string-db.org/network/1005057.BUAMB_368Chorismate mutase.
ffh protein networkhttps://string-db.org/network/1005057.BUAMB_369Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nasce [...]
rpsP protein networkhttps://string-db.org/network/1005057.BUAMB_37030S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
rimM protein networkhttps://string-db.org/network/1005057.BUAMB_37116S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19 [...]
trmD protein networkhttps://string-db.org/network/1005057.BUAMB_372tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rplS protein networkhttps://string-db.org/network/1005057.BUAMB_37350S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
tldD protein networkhttps://string-db.org/network/1005057.BUAMB_374TldD protein.
aroD protein networkhttps://string-db.org/network/1005057.BUAMB_3753-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
fis protein networkhttps://string-db.org/network/1005057.BUAMB_376Factor-for-inversion stimulation protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family [...]
rluD protein networkhttps://string-db.org/network/1005057.BUAMB_377Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
bamD protein networkhttps://string-db.org/network/1005057.BUAMB_378Part of large protein complex involved in outer membrane protein biogenesis.
alaS protein networkhttps://string-db.org/network/1005057.BUAMB_379alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
csrA protein networkhttps://string-db.org/network/1005057.BUAMB_380Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid g [...]
gshA protein networkhttps://string-db.org/network/1005057.BUAMB_383Glutamate-cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
endA protein networkhttps://string-db.org/network/1005057.BUAMB_385Endonuclease I.
rsmE protein networkhttps://string-db.org/network/1005057.BUAMB_38616S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
rpiA protein networkhttps://string-db.org/network/1005057.BUAMB_387Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
glnS protein networkhttps://string-db.org/network/1005057.BUAMB_391glutaminyl-tRNA synthetase.
pyrG protein networkhttps://string-db.org/network/1005057.BUAMB_392CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the [...]
eno protein networkhttps://string-db.org/network/1005057.BUAMB_393Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
nlpD protein networkhttps://string-db.org/network/1005057.BUAMB_394Lipoprotein NlpD precursor.
ispF protein networkhttps://string-db.org/network/1005057.BUAMB_3952-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
ispD protein networkhttps://string-db.org/network/1005057.BUAMB_3962-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to [...]
cysC protein networkhttps://string-db.org/network/1005057.BUAMB_398Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
cysN protein networkhttps://string-db.org/network/1005057.BUAMB_399Sulfate adenylate transferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPa [...]
cysD protein networkhttps://string-db.org/network/1005057.BUAMB_400Sulfate adenylyltransferase subunit 2.
cysG protein networkhttps://string-db.org/network/1005057.BUAMB_401Ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD [...]
cysH protein networkhttps://string-db.org/network/1005057.BUAMB_402Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
cysI protein networkhttps://string-db.org/network/1005057.BUAMB_403Sulfite reductase subunit beta; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosyn [...]
cysJ protein networkhttps://string-db.org/network/1005057.BUAMB_404Sulfite reductase (NADPH) flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities [...]
dsbA protein networkhttps://string-db.org/network/1005057.BUAMB_405Thiol:disulfide interchange protein DsbA precursor; Belongs to the thioredoxin family.
polA protein networkhttps://string-db.org/network/1005057.BUAMB_406DNA polymerase I.
yihA protein networkhttps://string-db.org/network/1005057.BUAMB_407Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase sup [...]
typA protein networkhttps://string-db.org/network/1005057.BUAMB_408GTP-binding protein BipA.
gmk protein networkhttps://string-db.org/network/1005057.BUAMB_409Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
ygfZ protein networkhttps://string-db.org/network/1005057.BUAMB_410Folate-binding protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via [...]
prfB protein networkhttps://string-db.org/network/1005057.BUAMB_411Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
lysS protein networkhttps://string-db.org/network/1005057.BUAMB_412lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
lysA protein networkhttps://string-db.org/network/1005057.BUAMB_413Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
lgt protein networkhttps://string-db.org/network/1005057.BUAMB_414Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
thyA protein networkhttps://string-db.org/network/1005057.BUAMB_415Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...]
miaB protein networkhttps://string-db.org/network/1005057.BUAMB_416Isopentenyl-adenosine A37 tRNA methylthiolase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i [...]
ybeY protein networkhttps://string-db.org/network/1005057.BUAMB_417Conserved protein involved in translation; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA [...]
ybeX protein networkhttps://string-db.org/network/1005057.BUAMB_418Putative ion transport protein.
leuS protein networkhttps://string-db.org/network/1005057.BUAMB_419leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
holA protein networkhttps://string-db.org/network/1005057.BUAMB_420DNA polymerase III delta subunit.
nadD protein networkhttps://string-db.org/network/1005057.BUAMB_421Nicotinate-mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
sirA protein networkhttps://string-db.org/network/1005057.BUAMB_422Sulfur transfer protein SirA; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the m [...]
asd protein networkhttps://string-db.org/network/1005057.BUAMB_423Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the as [...]
yhgN protein networkhttps://string-db.org/network/1005057.BUAMB_424Putative dITP- and XTP- hydrolase.
pgk protein networkhttps://string-db.org/network/1005057.BUAMB_425Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
fba protein networkhttps://string-db.org/network/1005057.BUAMB_426Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphat [...]
mscS protein networkhttps://string-db.org/network/1005057.BUAMB_427Mechanosensitive channel.
recC protein networkhttps://string-db.org/network/1005057.BUAMB_428Exodeoxyribonuclease V 125 kDa polypeptide; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive AT [...]
recB protein networkhttps://string-db.org/network/1005057.BUAMB_429Exodeoxyribonuclease V 135 kDa polypeptide; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive AT [...]
recD protein networkhttps://string-db.org/network/1005057.BUAMB_430Exodeoxyribonuclease V 67 kDa polypeptide; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP [...]
mltA protein networkhttps://string-db.org/network/1005057.BUAMB_432Murein transglycosylase A; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
ribE protein networkhttps://string-db.org/network/1005057.BUAMB_4336,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
ribD1 protein networkhttps://string-db.org/network/1005057.BUAMB_435Riboflavin deaminase; APS ortholog shorter than E. coli, ribD1/2 fused in E. coli.
ribD2 protein networkhttps://string-db.org/network/1005057.BUAMB_436Riboflavin reductase; APS ortholog shorter than E. coli, ribD1/2 fused in E. coli.
nusB protein networkhttps://string-db.org/network/1005057.BUAMB_437Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequ [...]
dxs protein networkhttps://string-db.org/network/1005057.BUAMB_4381-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (D [...]
yajR protein networkhttps://string-db.org/network/1005057.BUAMB_440MFS transporter; N terminal truncation; 9T homopolymer, 1 bp deletion.
yccK protein networkhttps://string-db.org/network/1005057.BUAMB_441Sulfur transfer protein; Part of a sulfur-relay system.
cyoE protein networkhttps://string-db.org/network/1005057.BUAMB_442Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
cyoD protein networkhttps://string-db.org/network/1005057.BUAMB_443Cytochrome O ubiquinol oxidase subunit IV.
cyoC protein networkhttps://string-db.org/network/1005057.BUAMB_444Cytochrome O ubiquinol oxidase subunit III.
cyoB protein networkhttps://string-db.org/network/1005057.BUAMB_445Cytochrome O ubiquinol oxidase subunit I; Belongs to the heme-copper respiratory oxidase family.
cyoA protein networkhttps://string-db.org/network/1005057.BUAMB_446Cytochrome O ubiquinol oxidase subunit II.
tig protein networkhttps://string-db.org/network/1005057.BUAMB_448Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs t [...]
clpP protein networkhttps://string-db.org/network/1005057.BUAMB_449ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
clpX protein networkhttps://string-db.org/network/1005057.BUAMB_450ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the ab [...]
lon protein networkhttps://string-db.org/network/1005057.BUAMB_451ATP-dependent protease LA; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for [...]
ppiD protein networkhttps://string-db.org/network/1005057.BUAMB_452Peptidyl-prolyl cis-trans isomerase D.
mdlA protein networkhttps://string-db.org/network/1005057.BUAMB_453Multidrug resistance-like ATP-binding protein Mdl.
mdlB protein networkhttps://string-db.org/network/1005057.BUAMB_454Multidrug resistance-like ATP-binding protein MdlB.
dnaX protein networkhttps://string-db.org/network/1005057.BUAMB_456DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' t [...]
ybaB protein networkhttps://string-db.org/network/1005057.BUAMB_457Conserved DNA-binding protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
htpG protein networkhttps://string-db.org/network/1005057.BUAMB_458Heat shock protein 90; Molecular chaperone. Has ATPase activity.
adk protein networkhttps://string-db.org/network/1005057.BUAMB_459Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
folD protein networkhttps://string-db.org/network/1005057.BUAMB_461Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10 [...]
cysS protein networkhttps://string-db.org/network/1005057.BUAMB_462cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
ybeD protein networkhttps://string-db.org/network/1005057.BUAMB_463Conserved protein; Belongs to the UPF0250 family.
cspE protein networkhttps://string-db.org/network/1005057.BUAMB_464Cold shock protein CspE.
aroE protein networkhttps://string-db.org/network/1005057.BUAMB_468Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshi [...]
rimN protein networkhttps://string-db.org/network/1005057.BUAMB_469Protein involved in synthesis of threonylcarbamoyladenosine-modified tRNA; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons [...]
smg protein networkhttps://string-db.org/network/1005057.BUAMB_470Smg protein; Belongs to the Smg family.
def protein networkhttps://string-db.org/network/1005057.BUAMB_471Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
fmt protein networkhttps://string-db.org/network/1005057.BUAMB_472methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
rplQ protein networkhttps://string-db.org/network/1005057.BUAMB_47350S ribosomal protein L17; Alpha operon.
rpoA protein networkhttps://string-db.org/network/1005057.BUAMB_474DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpsD protein networkhttps://string-db.org/network/1005057.BUAMB_47530S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpsK protein networkhttps://string-db.org/network/1005057.BUAMB_47630S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsM protein networkhttps://string-db.org/network/1005057.BUAMB_47730S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpmJ protein networkhttps://string-db.org/network/1005057.BUAMB_47850S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
secY protein networkhttps://string-db.org/network/1005057.BUAMB_479Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at t [...]
rplO protein networkhttps://string-db.org/network/1005057.BUAMB_48050S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
rpmD protein networkhttps://string-db.org/network/1005057.BUAMB_48150S ribosomal protein L30.
rpsE protein networkhttps://string-db.org/network/1005057.BUAMB_48230S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 fam [...]
rplR protein networkhttps://string-db.org/network/1005057.BUAMB_48350S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
rplF protein networkhttps://string-db.org/network/1005057.BUAMB_48450S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rpsH protein networkhttps://string-db.org/network/1005057.BUAMB_48530S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to [...]
rpsN protein networkhttps://string-db.org/network/1005057.BUAMB_48630S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the un [...]
rplE protein networkhttps://string-db.org/network/1005057.BUAMB_48750S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rplX protein networkhttps://string-db.org/network/1005057.BUAMB_48850S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplN protein networkhttps://string-db.org/network/1005057.BUAMB_48950S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rpsQ protein networkhttps://string-db.org/network/1005057.BUAMB_49030S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rpmC protein networkhttps://string-db.org/network/1005057.BUAMB_49150S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
rplP protein networkhttps://string-db.org/network/1005057.BUAMB_49250S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsC protein networkhttps://string-db.org/network/1005057.BUAMB_49330S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplV protein networkhttps://string-db.org/network/1005057.BUAMB_49450S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wal [...]
rpsS protein networkhttps://string-db.org/network/1005057.BUAMB_49530S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplB protein networkhttps://string-db.org/network/1005057.BUAMB_49650S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rplW protein networkhttps://string-db.org/network/1005057.BUAMB_49750S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplD protein networkhttps://string-db.org/network/1005057.BUAMB_49850S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
rplC protein networkhttps://string-db.org/network/1005057.BUAMB_49950S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rpsJ protein networkhttps://string-db.org/network/1005057.BUAMB_50030S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
tufA protein networkhttps://string-db.org/network/1005057.BUAMB_501Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
fusA protein networkhttps://string-db.org/network/1005057.BUAMB_502Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
rpsG protein networkhttps://string-db.org/network/1005057.BUAMB_50330S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
rpsL protein networkhttps://string-db.org/network/1005057.BUAMB_50430S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S an [...]
yheL protein networkhttps://string-db.org/network/1005057.BUAMB_505Sulfur transfer complex subunit TusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
yheM protein networkhttps://string-db.org/network/1005057.BUAMB_506Sulfur relay protein TusC; Belongs to the DsrF/TusC family.
yheN protein networkhttps://string-db.org/network/1005057.BUAMB_507Sulfur transfer complex subunit TusD.
fkpA protein networkhttps://string-db.org/network/1005057.BUAMB_508FKBP-type peptidyl-prolyl cis-trans isomerase FkpA precursor; APS ortholog shorter than E. coli.
tsgA protein networkhttps://string-db.org/network/1005057.BUAMB_509MFS transporter.
trpS protein networkhttps://string-db.org/network/1005057.BUAMB_510tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
rpe protein networkhttps://string-db.org/network/1005057.BUAMB_511Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
aroB protein networkhttps://string-db.org/network/1005057.BUAMB_5123-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
aroK protein networkhttps://string-db.org/network/1005057.BUAMB_513Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
deoD protein networkhttps://string-db.org/network/1005057.BUAMB_515Purine nucleoside phosphorylase.
deoB protein networkhttps://string-db.org/network/1005057.BUAMB_516Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
prfC protein networkhttps://string-db.org/network/1005057.BUAMB_517Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for U [...]
nfuA protein networkhttps://string-db.org/network/1005057.BUAMB_518Iron-sulfur cluster scaffold protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/ [...]
bioH protein networkhttps://string-db.org/network/1005057.BUAMB_519Carboxylesterase; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid syn [...]
ssb protein networkhttps://string-db.org/network/1005057.BUAMB_520Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action du [...]
dnaB protein networkhttps://string-db.org/network/1005057.BUAMB_521Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
gshB protein networkhttps://string-db.org/network/1005057.BUAMB_522Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
yqgF protein networkhttps://string-db.org/network/1005057.BUAMB_523Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
yggW protein networkhttps://string-db.org/network/1005057.BUAMB_524Putative oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cl [...]
trmI protein networkhttps://string-db.org/network/1005057.BUAMB_525tRNA (m7G46) methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
mutY protein networkhttps://string-db.org/network/1005057.BUAMB_526A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
yggX protein networkhttps://string-db.org/network/1005057.BUAMB_527Protein that protects iron-sulfur proteins against oxidative damage; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repai [...]
murI protein networkhttps://string-db.org/network/1005057.BUAMB_528Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
yeeX protein networkhttps://string-db.org/network/1005057.BUAMB_530Conserved protein; Belongs to the UPF0265 family.
pyrE protein networkhttps://string-db.org/network/1005057.BUAMB_533Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
dut protein networkhttps://string-db.org/network/1005057.BUAMB_534Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intrace [...]
cysQ protein networkhttps://string-db.org/network/1005057.BUAMB_535CysQ protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
rplI protein networkhttps://string-db.org/network/1005057.BUAMB_53650S ribosomal protein L9; Binds to the 23S rRNA.
rpsR protein networkhttps://string-db.org/network/1005057.BUAMB_53730S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
rpsF protein networkhttps://string-db.org/network/1005057.BUAMB_53830S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
rnr protein networkhttps://string-db.org/network/1005057.BUAMB_539VacB protein; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily.
purA protein networkhttps://string-db.org/network/1005057.BUAMB_540Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
hflC protein networkhttps://string-db.org/network/1005057.BUAMB_541FtsH protease regulator HflC; HflC and HflK could regulate a protease.
hflK protein networkhttps://string-db.org/network/1005057.BUAMB_542HflK protein; HflC and HflK could encode or regulate a protease.
miaA protein networkhttps://string-db.org/network/1005057.BUAMB_543tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to th [...]
mtlD protein networkhttps://string-db.org/network/1005057.BUAMB_544Mannitol-1-phosphate 5-dehydrogenase.
mtlA protein networkhttps://string-db.org/network/1005057.BUAMB_545PTS system mannitol-specific IIABC component.
pgi protein networkhttps://string-db.org/network/1005057.BUAMB_546Glucose-6-phosphate isomerase; Belongs to the GPI family.
orn protein networkhttps://string-db.org/network/1005057.BUAMB_547Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
amiB protein networkhttps://string-db.org/network/1005057.BUAMB_549N-acetylmuramoyl-L-alanine amidase precursor.
rpmE protein networkhttps://string-db.org/network/1005057.BUAMB_55050S ribosomal protein L31; Binds the 23S rRNA.
hslV protein networkhttps://string-db.org/network/1005057.BUAMB_551ATP-dependent protease peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
hslU protein networkhttps://string-db.org/network/1005057.BUAMB_552ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by [...]
ibpA protein networkhttps://string-db.org/network/1005057.BUAMB_55316 kDa heat shock protein A; Belongs to the small heat shock protein (HSP20) family.
fpr protein networkhttps://string-db.org/network/1005057.BUAMB_554ferredoxin-NADP reductase.
poxA protein networkhttps://string-db.org/network/1005057.BUAMB_555lysyl-tRNA synthetase; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent activation [...]
coaD protein networkhttps://string-db.org/network/1005057.BUAMB_556Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD [...]
yhiQ protein networkhttps://string-db.org/network/1005057.BUAMB_558Putative SAM-dependent methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA.
pitA protein networkhttps://string-db.org/network/1005057.BUAMB_559Low-affinity inorganic phosphate transporter.
ynfM protein networkhttps://string-db.org/network/1005057.BUAMB_560MFS transporter.
dapF protein networkhttps://string-db.org/network/1005057.BUAMB_561Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
cyaY protein networkhttps://string-db.org/network/1005057.BUAMB_562CyaY protein; Belongs to the frataxin family.
hemC protein networkhttps://string-db.org/network/1005057.BUAMB_563Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
rho protein networkhttps://string-db.org/network/1005057.BUAMB_568Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
trxA protein networkhttps://string-db.org/network/1005057.BUAMB_569Thioredoxin; Belongs to the thioredoxin family.
rep protein networkhttps://string-db.org/network/1005057.BUAMB_570ATP-dependent DNA helicase Rep.
ilvC protein networkhttps://string-db.org/network/1005057.BUAMB_571Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
ilvD protein networkhttps://string-db.org/network/1005057.BUAMB_572Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
iscS protein networkhttps://string-db.org/network/1005057.BUAMB_574Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental [...]
iscU protein networkhttps://string-db.org/network/1005057.BUAMB_575Scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters [...]
hscB protein networkhttps://string-db.org/network/1005057.BUAMB_576Chaperone protein HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
hscA protein networkhttps://string-db.org/network/1005057.BUAMB_577Heat shock protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in th [...]
fdx protein networkhttps://string-db.org/network/1005057.BUAMB_578Ferredoxin 2fe-2s.
der protein networkhttps://string-db.org/network/1005057.BUAMB_579GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) G [...]
yfgM protein networkhttps://string-db.org/network/1005057.BUAMB_580Conserved protein.