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CAMK2D CAMK2D CTNNA3 CTNNA3 ENSMNEP00000034665 ENSMNEP00000034665 DSP DSP ANK2 ANK2 ATP2A1 ATP2A1 ENSMNEP00000026506 ENSMNEP00000026506 JUP JUP RANGRF RANGRF ATP2A2 ATP2A2 CACNA1C CACNA1C GATA4 GATA4 SRI SRI PKP2 PKP2 DSG2 DSG2 PDE4D PDE4D BIN1 BIN1 ENSMNEP00000006277 ENSMNEP00000006277 DSC2 DSC2 GJA5 GJA5 SCN5A SCN5A ENSMNEP00000003112 ENSMNEP00000003112 RYR2 RYR2 PLN PLN SUMO1 SUMO1 PDE4B PDE4B AKAP9 AKAP9 ENSMNEP00000042578 ENSMNEP00000042578 TRPM4 TRPM4 DLG1 DLG1 STC1 STC1 CAV1 CAV1 CAV3 CAV3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
CTNNA3Catenin alpha 3. (895 aa)
ENSMNEP00000034665Uncharacterized protein. (98 aa)
DSPDesmoplakin. (2272 aa)
ANK2Ankyrin 2. (3921 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1030 aa)
ENSMNEP00000026506Uncharacterized protein. (90 aa)
JUPJunction plakoglobin. (745 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
GATA4GATA binding protein 4. (443 aa)
SRISorcin. (198 aa)
PKP2Plakophilin 2. (869 aa)
DSG2Desmoglein 2. (1118 aa)
PDE4DPhosphodiesterase. (809 aa)
BIN1Bridging integrator 1. (608 aa)
ENSMNEP00000006277Rad60-SLD domain-containing protein. (67 aa)
DSC2Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (901 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
ENSMNEP00000003112Small ubiquitin-related modifier. (113 aa)
RYR2Ryanodine receptor 2. (4951 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
SUMO1Ubiquitin-like domain-containing protein. (146 aa)
PDE4BPhosphodiesterase. (736 aa)
AKAP9A-kinase anchoring protein 9. (3909 aa)
ENSMNEP00000042578Rad60-SLD domain-containing protein. (65 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (992 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (947 aa)
STC1Stanniocalcin 1. (247 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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