(23 nodes) Regulation of dopamine secretion network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103466506	Synaptotagmin VIIa. (606 aa)
	syt4	Synaptotagmin IV. (471 aa)
	LOC103466244	Synaptotagmin IXb. (529 aa)
	LOC103481534	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family. (234 aa)
	LOC103467654	Synaptotagmin IIa. (430 aa)
	LOC103466664	Synaptotagmin Ib. (387 aa)
	LOC103462615	C2 domain-containing protein. (380 aa)
	dtnbp1	Dystrobrevin binding protein 1b. (229 aa)
	LOC103481621	Synaptotagmin XV. (304 aa)
	syt3	Synaptotagmin III. (558 aa)
	syt12	Synaptotagmin XII. (423 aa)
	SYT2	Synaptotagmin 2. (413 aa)
	sncg	Gamma-synuclein; Belongs to the synuclein family. (122 aa)
	LOC103462870	Synaptotagmin IXa. (559 aa)
	syt11	Synaptotagmin XIb. (468 aa)
	LOC103473856	Uncharacterized protein; Belongs to the synuclein family. (149 aa)
	drd3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (455 aa)
	LOC103467834	Synaptotagmin VIa. (541 aa)
	LOC103481238	Synaptotagmin Vb. (424 aa)
	pink1	PTEN induced kinase 1. (575 aa)
	syt1	Synaptotagmin Ia. (422 aa)
	syt10	Synaptotagmin X. (434 aa)
	LOC103462425	Synaptotagmin VIIb. (468 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103462615	LOC103462870	ENSPREP00000012268	ENSPREP00000019678	C2 domain-containing protein.	Synaptotagmin IXa.	0.418
LOC103462615	LOC103466244	ENSPREP00000012268	ENSPREP00000002121	C2 domain-containing protein.	Synaptotagmin IXb.	0.418
LOC103462615	LOC103466664	ENSPREP00000012268	ENSPREP00000008646	C2 domain-containing protein.	Synaptotagmin Ib.	0.623
LOC103462615	LOC103467654	ENSPREP00000012268	ENSPREP00000007201	C2 domain-containing protein.	Synaptotagmin IIa.	0.623
LOC103462615	LOC103481238	ENSPREP00000012268	ENSPREP00000032319	C2 domain-containing protein.	Synaptotagmin Vb.	0.623
LOC103462615	SYT2	ENSPREP00000012268	ENSPREP00000018469	C2 domain-containing protein.	Synaptotagmin 2.	0.623
LOC103462615	syt1	ENSPREP00000012268	ENSPREP00000033265	C2 domain-containing protein.	Synaptotagmin Ia.	0.623
LOC103462870	LOC103462615	ENSPREP00000019678	ENSPREP00000012268	Synaptotagmin IXa.	C2 domain-containing protein.	0.418
LOC103462870	LOC103466664	ENSPREP00000019678	ENSPREP00000008646	Synaptotagmin IXa.	Synaptotagmin Ib.	0.456
LOC103462870	LOC103467654	ENSPREP00000019678	ENSPREP00000007201	Synaptotagmin IXa.	Synaptotagmin IIa.	0.468
LOC103462870	LOC103481238	ENSPREP00000019678	ENSPREP00000032319	Synaptotagmin IXa.	Synaptotagmin Vb.	0.463
LOC103462870	SYT2	ENSPREP00000019678	ENSPREP00000018469	Synaptotagmin IXa.	Synaptotagmin 2.	0.454
LOC103462870	syt1	ENSPREP00000019678	ENSPREP00000033265	Synaptotagmin IXa.	Synaptotagmin Ia.	0.463
LOC103462870	syt11	ENSPREP00000019678	ENSPREP00000024936	Synaptotagmin IXa.	Synaptotagmin XIb.	0.418
LOC103462870	syt4	ENSPREP00000019678	ENSPREP00000001860	Synaptotagmin IXa.	Synaptotagmin IV.	0.418
LOC103466244	LOC103462615	ENSPREP00000002121	ENSPREP00000012268	Synaptotagmin IXb.	C2 domain-containing protein.	0.418
LOC103466244	LOC103466664	ENSPREP00000002121	ENSPREP00000008646	Synaptotagmin IXb.	Synaptotagmin Ib.	0.455
LOC103466244	LOC103467654	ENSPREP00000002121	ENSPREP00000007201	Synaptotagmin IXb.	Synaptotagmin IIa.	0.454
LOC103466244	LOC103481238	ENSPREP00000002121	ENSPREP00000032319	Synaptotagmin IXb.	Synaptotagmin Vb.	0.475
LOC103466244	SYT2	ENSPREP00000002121	ENSPREP00000018469	Synaptotagmin IXb.	Synaptotagmin 2.	0.466