Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSDARP00000125042 | foxa2 | ENSDARP00000125042 | ENSDARP00000007827 | Patched 1. | Forkhead box protein A2; May play a crucial role in specification of both the axial mesendoderm and the ventral nervous system. | 0.424 |
| ENSDARP00000125042 | gli1 | ENSDARP00000125042 | ENSDARP00000129932 | Patched 1. | GLI family zinc finger 1. | 0.961 |
| ENSDARP00000125042 | gli2a | ENSDARP00000125042 | ENSDARP00000010693 | Patched 1. | GLI family zinc finger 2a. | 0.959 |
| ENSDARP00000125042 | nkx2.2a | ENSDARP00000125042 | ENSDARP00000153588 | Patched 1. | Homeobox protein Nkx-2.2a; Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (By similarity). | 0.609 |
| ENSDARP00000125042 | notch1a | ENSDARP00000125042 | ENSDARP00000137942 | Patched 1. | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | 0.629 |
| ENSDARP00000125042 | smo | ENSDARP00000125042 | ENSDARP00000013486 | Patched 1. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.996 |
| aldh1a2 | notch1a | ENSDARP00000070001 | ENSDARP00000137942 | Aldehyde dehydrogenase 1 family, member A2; Belongs to the aldehyde dehydrogenase family. | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | 0.633 |
| aldh1a2 | vegfaa | ENSDARP00000070001 | ENSDARP00000133415 | Aldehyde dehydrogenase 1 family, member A2; Belongs to the aldehyde dehydrogenase family. | Vascular endothelial growth factor A-A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels. Acts both upstream of kdr and tie1 to stimulate endothelial cell differentiation, and upstream of gata1 to stimulate hematopoietic cell differentiation. | 0.452 |
| chrd | foxa2 | ENSDARP00000045109 | ENSDARP00000007827 | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity); Belongs to the chordin family. | Forkhead box protein A2; May play a crucial role in specification of both the axial mesendoderm and the ventral nervous system. | 0.671 |
| chrd | nkx2.2a | ENSDARP00000045109 | ENSDARP00000153588 | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity); Belongs to the chordin family. | Homeobox protein Nkx-2.2a; Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (By similarity). | 0.555 |
| chrd | notch1a | ENSDARP00000045109 | ENSDARP00000137942 | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity); Belongs to the chordin family. | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | 0.483 |
| chrd | smad2 | ENSDARP00000045109 | ENSDARP00000106756 | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity); Belongs to the chordin family. | Mothers against decapentaplegic homolog 2; Promotes differentiation of dorsal tissues. May be involved in the mediation of Ndr2 signaling during mesoderm and axis formation during embryogenesis. | 0.693 |
| dla | notch1a | ENSDARP00000013374 | ENSDARP00000137942 | Delta-like protein A; Acts as a ligand for Notch receptors and is involved in primary neurogenesis. Can activate Notch receptors, thereby playing a key role in lateral inhibition, a process that prevents the immediate neighbors of each nascent neural cell from simultaneously embarking on neural differentiation. Required for boundary formation during segmentation of the hindbrain. Required for midline cell fate specification prior to germ layer formation; regulates specification of floorplate, notochord and hypochord. In inner ear, it prevents adjacent cells from adopting the same cell [...] | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | 0.863 |
| foxa2 | ENSDARP00000125042 | ENSDARP00000007827 | ENSDARP00000125042 | Forkhead box protein A2; May play a crucial role in specification of both the axial mesendoderm and the ventral nervous system. | Patched 1. | 0.424 |
| foxa2 | chrd | ENSDARP00000007827 | ENSDARP00000045109 | Forkhead box protein A2; May play a crucial role in specification of both the axial mesendoderm and the ventral nervous system. | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity); Belongs to the chordin family. | 0.671 |
| foxa2 | gli1 | ENSDARP00000007827 | ENSDARP00000129932 | Forkhead box protein A2; May play a crucial role in specification of both the axial mesendoderm and the ventral nervous system. | GLI family zinc finger 1. | 0.469 |
| foxa2 | gli2a | ENSDARP00000007827 | ENSDARP00000010693 | Forkhead box protein A2; May play a crucial role in specification of both the axial mesendoderm and the ventral nervous system. | GLI family zinc finger 2a. | 0.585 |
| foxa2 | myca | ENSDARP00000007827 | ENSDARP00000100455 | Forkhead box protein A2; May play a crucial role in specification of both the axial mesendoderm and the ventral nervous system. | Transcriptional regulator Myc-A; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. | 0.466 |
| foxa2 | nkx2.2a | ENSDARP00000007827 | ENSDARP00000153588 | Forkhead box protein A2; May play a crucial role in specification of both the axial mesendoderm and the ventral nervous system. | Homeobox protein Nkx-2.2a; Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (By similarity). | 0.881 |
| foxa2 | notch1a | ENSDARP00000007827 | ENSDARP00000137942 | Forkhead box protein A2; May play a crucial role in specification of both the axial mesendoderm and the ventral nervous system. | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | 0.504 |
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