108 items (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102350907	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	M3XL18_LATCH	Uncharacterized protein. (484 aa)
	TOLLIP	Toll interacting protein. (274 aa)
	LRRC74A	Leucine rich repeat containing 74A. (456 aa)
	LRRC71	Uncharacterized protein. (545 aa)
	LOC102349804	Proteasome subunit alpha type. (274 aa)
	PELI2	Pellino E3 ubiquitin protein ligase family member 2. (420 aa)
	NFKBIB	NFKB inhibitor beta. (397 aa)
	UBE2V1	UBIQUITIN_CONJUGAT_2 domain-containing protein. (153 aa)
	NLRX1	NLR family member X1. (855 aa)
	NFKBIA	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (298 aa)
	TAB2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (691 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
	H3BAP4_LATCH	EF-hand domain-containing protein. (105 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (172 aa)
	TAB3	TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (672 aa)
	LRRC74B	Leucine rich repeat containing 74B. (418 aa)
	NFKB2	Nuclear factor kappa B subunit 2. (914 aa)
	IRAK4	Interleukin 1 receptor associated kinase 4. (454 aa)
	IL1RAP	Interleukin 1 receptor accessory protein. (688 aa)
	LOC102350357	Uncharacterized protein. (577 aa)
	LRRC34	Leucine rich repeat containing 34. (343 aa)
	PELI1	Pellino E3 ubiquitin protein ligase 1. (445 aa)
	H3B7W4_LATCH	Uncharacterized protein. (725 aa)
	LRRC31	Leucine rich repeat containing 31. (498 aa)
	VWC2L	Von Willebrand factor C domain containing 2 like. (176 aa)
	PSMD8	Proteasome 26S subunit, non-ATPase 8. (309 aa)
	H3B6K7_LATCH	IKKbetaNEMObind domain-containing protein. (241 aa)
	LOC102350961	Proteasome subunit beta. (260 aa)
	LOC102358862	Proteasome subunit beta. (272 aa)
	PSMB11	Proteasome subunit beta. (269 aa)
	H3B5B6_LATCH	NACHT domain-containing protein. (692 aa)
	H3B531_LATCH	Uncharacterized protein. (868 aa)
	N4BP1	NEDD4 binding protein 1. (806 aa)
	USP14	Ubiquitin carboxyl-terminal hydrolase. (490 aa)
	H3B3Q3_LATCH	Uncharacterized protein. (246 aa)
	VWC2	Von Willebrand factor C domain containing 2. (270 aa)
	PSMB9	Proteasome subunit beta. (219 aa)
	H3B2N1_LATCH	NACHT domain-containing protein. (429 aa)
	PSMB8	Proteasome subunit beta. (271 aa)
	UBE2V2-2	Ubiquitin-conjugating enzyme E2 variant 2. (102 aa)
	H3AZ93_LATCH	NACHT domain-containing protein. (591 aa)
	IRAK1	Interleukin 1 receptor associated kinase 1. (673 aa)
	MFSD1	Major facilitator superfamily domain containing 1. (518 aa)
	PSMD10	Proteasome 26S subunit, non-ATPase 10. (234 aa)
	PSMA1	Proteasome subunit alpha type. (269 aa)
	MAP3K3	Mitogen-activated protein kinase kinase kinase 3. (658 aa)
	SQSTM1	Sequestosome 1. (441 aa)
	H3AVW1_LATCH	NACHT domain-containing protein. (614 aa)
	H3AVE1_LATCH	NACHT domain-containing protein. (574 aa)
	LOC102361553	Si:dkey-118k5.3. (792 aa)
	H3AUI4_LATCH	Uncharacterized protein. (597 aa)
	H3AUI0_LATCH	NACHT domain-containing protein. (572 aa)
	PSMA8	Proteasome subunit alpha type. (251 aa)
	LRRC45	Leucine rich repeat containing 45. (679 aa)
	H3AQ35_LATCH	NACHT domain-containing protein. (880 aa)
	H3APC7_LATCH	NACHT domain-containing protein. (686 aa)
	H3ANY4_LATCH	NACHT domain-containing protein. (596 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7. (580 aa)
	LOC102354461	Uncharacterized protein. (1107 aa)
	H3AM29_LATCH	NACHT domain-containing protein. (549 aa)
	H3ALU7_LATCH	NACHT domain-containing protein. (877 aa)
	H3AKZ9_LATCH	NACHT domain-containing protein. (657 aa)
	H3AIB1_LATCH	Uncharacterized protein. (909 aa)
	KXD1	Ubiquitin-like domain-containing protein. (231 aa)
	H3AH96_LATCH	Uncharacterized protein. (227 aa)
	H3AGQ6_LATCH	Uncharacterized protein. (442 aa)
	LOC102346630	Im:7160594. (484 aa)
	RPS27A	Ribosomal protein S27a. (156 aa)
	UBE2N	Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
	H3ADL4_LATCH	Uncharacterized protein. (396 aa)
	H3ADB2_LATCH	NACHT domain-containing protein. (685 aa)
	H3AC12_LATCH	RNase_Zc3h12a domain-containing protein. (910 aa)
	H3ABX3_LATCH	NACHT domain-containing protein. (488 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (700 aa)
	H3ABP0_LATCH	Uncharacterized protein. (387 aa)
	LOC102358143	NACHT domain-containing protein. (1014 aa)
	S100B	S100 calcium binding protein B; Belongs to the S-100 family. (114 aa)
	IL1R2	Interleukin 1 receptor type 2. (378 aa)
	H3A8H2_LATCH	Uncharacterized protein. (541 aa)
	RBX1	Ring-box 1. (108 aa)
	PSMA7	Proteasome subunit alpha type. (251 aa)
	TONSL	Tonsoku like, DNA repair protein. (1417 aa)
	IKBKG	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (435 aa)
	H3A4V8_LATCH	Proteasome subunit beta. (260 aa)
	H3A4J0_LATCH	NACHT domain-containing protein. (800 aa)
	MAP3K20	Uncharacterized protein. (792 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
	H3A1K7_LATCH	Uncharacterized protein. (297 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	LOC102346166	Ubiquitin-like domain-containing protein. (95 aa)
	PSME1	Proteasome activator subunit 1. (252 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (969 aa)
	H3A007_LATCH	Uncharacterized protein. (52 aa)
	PELI3	Pellino E3 ubiquitin protein ligase family member 3. (443 aa)
	PSME4	Proteasome activator subunit 4. (1848 aa)
	H2ZWW7_LATCH	NACHT domain-containing protein. (1035 aa)
	NKIRAS1	NFKB inhibitor interacting Ras like 1. (191 aa)
	APP	Amyloid beta precursor protein. (652 aa)
	IRAK3	Interleukin 1 receptor associated kinase 3. (546 aa)
	MAP3K2	Mitogen-activated protein kinase kinase kinase 2. (664 aa)
	PSME2	Proteasome activator subunit 2. (241 aa)
	H2ZT63_LATCH	Uncharacterized protein. (292 aa)
	TAB1	TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (436 aa)
	LRRC14	Uncharacterized protein. (206 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (730 aa)
	LOC102354587	Uncharacterized protein. (258 aa)
	H2ZSA7_LATCH	NACHT domain-containing protein. (707 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	NFKB1	ENSLACP00000001643	ENSLACP00000003071	Amyloid beta precursor protein.	Nuclear factor kappa B subunit 1.	0.513
APP	NFKB2	ENSLACP00000001643	ENSLACP00000018524	Amyloid beta precursor protein.	Nuclear factor kappa B subunit 2.	0.513
APP	S100B	ENSLACP00000001643	ENSLACP00000006063	Amyloid beta precursor protein.	S100 calcium binding protein B; Belongs to the S-100 family.	0.580
CHUK	CUL1	ENSLACP00000007128	ENSLACP00000003516	Component of inhibitor of nuclear factor kappa B kinase complex.	Cullin 1; Belongs to the cullin family.	0.651
CHUK	H2ZT63_LATCH	ENSLACP00000007128	ENSLACP00000000584	Component of inhibitor of nuclear factor kappa B kinase complex.	Uncharacterized protein.	0.413
CHUK	H2ZWW7_LATCH	ENSLACP00000007128	ENSLACP00000001888	Component of inhibitor of nuclear factor kappa B kinase complex.	NACHT domain-containing protein.	0.413
CHUK	H3A007_LATCH	ENSLACP00000007128	ENSLACP00000002978	Component of inhibitor of nuclear factor kappa B kinase complex.	Uncharacterized protein.	0.583
CHUK	H3A1K7_LATCH	ENSLACP00000007128	ENSLACP00000003528	Component of inhibitor of nuclear factor kappa B kinase complex.	Uncharacterized protein.	0.413
CHUK	H3A8H2_LATCH	ENSLACP00000007128	ENSLACP00000005943	Component of inhibitor of nuclear factor kappa B kinase complex.	Uncharacterized protein.	0.544
CHUK	H3ABP0_LATCH	ENSLACP00000007128	ENSLACP00000007061	Component of inhibitor of nuclear factor kappa B kinase complex.	Uncharacterized protein.	0.413
CHUK	H3ADL4_LATCH	ENSLACP00000007128	ENSLACP00000007735	Component of inhibitor of nuclear factor kappa B kinase complex.	Uncharacterized protein.	0.413
CHUK	H3AH96_LATCH	ENSLACP00000007128	ENSLACP00000009017	Component of inhibitor of nuclear factor kappa B kinase complex.	Uncharacterized protein.	0.413
CHUK	H3AUI4_LATCH	ENSLACP00000007128	ENSLACP00000013305	Component of inhibitor of nuclear factor kappa B kinase complex.	Uncharacterized protein.	0.623
CHUK	H3B2N1_LATCH	ENSLACP00000007128	ENSLACP00000016152	Component of inhibitor of nuclear factor kappa B kinase complex.	NACHT domain-containing protein.	0.413
CHUK	H3B6K7_LATCH	ENSLACP00000007128	ENSLACP00000017528	Component of inhibitor of nuclear factor kappa B kinase complex.	IKKbetaNEMObind domain-containing protein.	0.998
CHUK	IKBKG	ENSLACP00000007128	ENSLACP00000004753	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.831
CHUK	IRAK1	ENSLACP00000007128	ENSLACP00000014884	Component of inhibitor of nuclear factor kappa B kinase complex.	Interleukin 1 receptor associated kinase 1.	0.863
CHUK	IRAK4	ENSLACP00000007128	ENSLACP00000018448	Component of inhibitor of nuclear factor kappa B kinase complex.	Interleukin 1 receptor associated kinase 4.	0.647
CHUK	KXD1	ENSLACP00000007128	ENSLACP00000009213	Component of inhibitor of nuclear factor kappa B kinase complex.	Ubiquitin-like domain-containing protein.	0.671
CHUK	LOC102346166	ENSLACP00000007128	ENSLACP00000003410	Component of inhibitor of nuclear factor kappa B kinase complex.	Ubiquitin-like domain-containing protein.	0.508