(51 nodes) Actin filament organization network (Melampsora laricipopulina)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F4RKV7_MELLP	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (398 aa)
	F4RKX2_MELLP	Uncharacterized protein. (364 aa)
	F4RKX3_MELLP	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (410 aa)
	F4RLM8_MELLP	Uncharacterized protein. (329 aa)
	F4RMF7_MELLP	Uncharacterized protein; Belongs to the actin family. (442 aa)
	F4RMM8_MELLP	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (162 aa)
	F4RNR2_MELLP	Uncharacterized protein. (350 aa)
	F4RPW0_MELLP	FH2 domain-containing protein. (424 aa)
	F4RQ81_MELLP	Uncharacterized protein. (229 aa)
	F4RQK7_MELLP	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (160 aa)
	F4RQZ8_MELLP	Uncharacterized protein. (212 aa)
	F4R3J0_MELLP	Uncharacterized protein. (682 aa)
	F4R4G5_MELLP	Gelsolin-like domain-containing protein. (1384 aa)
	F4SCR1_MELLP	Uncharacterized protein. (87 aa)
	F4S9A5_MELLP	Uncharacterized protein. (691 aa)
	F4S990_MELLP	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (136 aa)
	F4S7S6_MELLP	Uncharacterized protein. (223 aa)
	F4S704_MELLP	Uncharacterized protein. (197 aa)
	F4S6W2_MELLP	GAR domain-containing protein. (2065 aa)
	F4S5V4_MELLP	Secreted protein. (279 aa)
	F4S2U1_MELLP	ENTH domain-containing protein. (492 aa)
	F4S2N8_MELLP	Uncharacterized protein. (887 aa)
	F4S0E8_MELLP	Uncharacterized protein. (720 aa)
	F4RZM9_MELLP	Uncharacterized protein. (126 aa)
	F4RXC4_MELLP	ANTH domain-containing protein. (184 aa)
	F4RV22_MELLP	SH3 domain-containing protein. (347 aa)
	F4RUT5_MELLP	Rho-GAP domain-containing protein. (927 aa)
	F4RUB1_MELLP	WD_REPEATS_REGION domain-containing protein. (541 aa)
	F4RU76_MELLP	Uncharacterized protein. (207 aa)
	F4RU04_MELLP	Secreted protein. (238 aa)
	F4RTM6_MELLP	Uncharacterized protein. (115 aa)
	F4RSK9_MELLP	Uncharacterized protein. (1175 aa)
	F4RSG2_MELLP	Ysc84 domain-containing protein. (298 aa)
	F4RS15_MELLP	HATPase_c domain-containing protein. (928 aa)
	F4R738_MELLP	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1313 aa)
	F4R7N5_MELLP	Uncharacterized protein. (616 aa)
	F4RAA3_MELLP	Uncharacterized protein. (283 aa)
	F4RAK2_MELLP	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
	F4RCE4_MELLP	Adenylyl cyclase-associated protein; Belongs to the CAP family. (531 aa)
	F4RRM7_MELLP	Uncharacterized protein. (498 aa)
	F4RCV0_MELLP	Uncharacterized protein. (210 aa)
	F4RDG1_MELLP	Uncharacterized protein. (529 aa)
	F4RDW5_MELLP	Uncharacterized protein. (1540 aa)
	F4RE24_MELLP	VHS domain-containing protein. (497 aa)
	F4REN7_MELLP	AIP3 domain-containing protein. (768 aa)
	F4RG60_MELLP	PINc domain-containing protein. (378 aa)
	F4RGN4_MELLP	Uncharacterized protein. (626 aa)
	F4RHJ1_MELLP	Uncharacterized protein. (161 aa)
	F4RIR3_MELLP	Uncharacterized protein. (221 aa)
	F4RKB4_MELLP	Uncharacterized protein. (1097 aa)
	F4RKN6_MELLP	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (302 aa)

Your Current Organism:

Melampsora laricipopulina

NCBI taxonomy Id: 747676
Other names: M. larici-populina 98AG31, Melampsora larici-populina 98AG31, Melampsora laricis-populina 98AG31

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F4R3J0_MELLP	F4R738_MELLP	F4R3J0	F4R738	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.874
F4R3J0_MELLP	F4RAA3_MELLP	F4R3J0	F4RAA3	Uncharacterized protein.	Uncharacterized protein.	0.470
F4R3J0_MELLP	F4RCV0_MELLP	F4R3J0	F4RCV0	Uncharacterized protein.	Uncharacterized protein.	0.470
F4R3J0_MELLP	F4RGN4_MELLP	F4R3J0	F4RGN4	Uncharacterized protein.	Uncharacterized protein.	0.457
F4R3J0_MELLP	F4RIR3_MELLP	F4R3J0	F4RIR3	Uncharacterized protein.	Uncharacterized protein.	0.470
F4R3J0_MELLP	F4RKV7_MELLP	F4R3J0	F4RKV7	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.626
F4R3J0_MELLP	F4RQ81_MELLP	F4R3J0	F4RQ81	Uncharacterized protein.	Uncharacterized protein.	0.470
F4R3J0_MELLP	F4RRM7_MELLP	F4R3J0	F4RRM7	Uncharacterized protein.	Uncharacterized protein.	0.981
F4R3J0_MELLP	F4RTM6_MELLP	F4R3J0	F4RTM6	Uncharacterized protein.	Uncharacterized protein.	0.470
F4R3J0_MELLP	F4RUB1_MELLP	F4R3J0	F4RUB1	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.412
F4R3J0_MELLP	F4RZM9_MELLP	F4R3J0	F4RZM9	Uncharacterized protein.	Uncharacterized protein.	0.772
F4R3J0_MELLP	F4S0E8_MELLP	F4R3J0	F4S0E8	Uncharacterized protein.	Uncharacterized protein.	0.470
F4R3J0_MELLP	F4S2U1_MELLP	F4R3J0	F4S2U1	Uncharacterized protein.	ENTH domain-containing protein.	0.483
F4R3J0_MELLP	F4S5V4_MELLP	F4R3J0	F4S5V4	Uncharacterized protein.	Secreted protein.	0.651
F4R3J0_MELLP	F4S704_MELLP	F4R3J0	F4S704	Uncharacterized protein.	Uncharacterized protein.	0.470
F4R4G5_MELLP	F4R7N5_MELLP	F4R4G5	F4R7N5	Gelsolin-like domain-containing protein.	Uncharacterized protein.	0.471
F4R4G5_MELLP	F4RGN4_MELLP	F4R4G5	F4RGN4	Gelsolin-like domain-containing protein.	Uncharacterized protein.	0.548
F4R4G5_MELLP	F4RKV7_MELLP	F4R4G5	F4RKV7	Gelsolin-like domain-containing protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.578
F4R4G5_MELLP	F4RNR2_MELLP	F4R4G5	F4RNR2	Gelsolin-like domain-containing protein.	Uncharacterized protein.	0.706
F4R4G5_MELLP	F4RRM7_MELLP	F4R4G5	F4RRM7	Gelsolin-like domain-containing protein.	Uncharacterized protein.	0.683