STRINGSTRING
ARAM_003216 ARAM_003216 ARAM_004273 ARAM_004273 ARAM_005997 ARAM_005997 hxB hxB uba4 uba4 ARAM_000407 ARAM_000407 ARAM_003541 ARAM_003541 ARAM_007286 ARAM_007286 cnxH cnxH ARAM_006239 ARAM_006239 ARAM_000061 ARAM_000061 ARAM_004448 ARAM_004448
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARAM_003216Uncharacterized protein. (81 aa)
ARAM_004273Putative thiosulfate sulfurtransferase. (344 aa)
ARAM_005997Uncharacterized protein. (380 aa)
hxBMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (827 aa)
uba4Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (1012 aa)
ARAM_000407Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (423 aa)
ARAM_003541Uncharacterized protein. (299 aa)
ARAM_007286Aminotran_5 domain-containing protein. (532 aa)
cnxHMolybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. (206 aa)
ARAM_006239Rhodanese domain-containing protein. (232 aa)
ARAM_000061tRNA splicing protein. (509 aa)
ARAM_004448Uncharacterized protein. (699 aa)
Your Current Organism:
Aspergillus rambellii
NCBI taxonomy Id: 308745
Other names: A. rambellii, ATCC 42001, CBS 101887, IBT 14580
Server load: low (34%) [HD]