STRINGSTRING
Esi_0061_0003 Esi_0061_0003 SHMT2-3 SHMT2-3 Esi_0090_0074 Esi_0090_0074 IPMS3 IPMS3 Esi_0009_0096 Esi_0009_0096 TIC-5 TIC-5 SK SK DHQ-SDH DHQ-SDH ASL ASL BCAT3-2 BCAT3-2 BCAT3 BCAT3 Esi_0081_0025 Esi_0081_0025 BCAT2 BCAT2 THA2 THA2 BCAT1 BCAT1 Esi_0072_0092 Esi_0072_0092 NAG-PR NAG-PR Esi_0070_0078 Esi_0070_0078 Esi_0070_0073 Esi_0070_0073 TIC20 TIC20 TIC-4 TIC-4 Esi_0007_0086 Esi_0007_0086 Esi_0007_0085 Esi_0007_0085 Esi_0002_0003 Esi_0002_0003 PSP PSP PYK PYK HIS8 HIS8 Esi_0188_0005 Esi_0188_0005 Esi_0188_0004 Esi_0188_0004 Esi_0187_0064 Esi_0187_0064 Esi_0187_0063 Esi_0187_0063 GAP-2 GAP-2 FBA1 FBA1 Esi_0183_0045 Esi_0183_0045 HSDH HSDH IGP-DH IGP-DH Esi_0179_0062 Esi_0179_0062 Esi_0175_0040 Esi_0175_0040 SAMS1 SAMS1 GAP GAP CBL2 CBL2 Esi_0164_0038 Esi_0164_0038 Esi_0163_0013 Esi_0163_0013 Esi_0016_0192 Esi_0016_0192 PDGH PDGH Esi_0016_0022 Esi_0016_0022 AS-B AS-B CBL1 CBL1 Esi_0143_0070 Esi_0143_0070 Esi_0138_0072 Esi_0138_0072 PGDH-2 PGDH-2 ARGA ARGA Esi_0130_0062 Esi_0130_0062 Esi_0109_0013 Esi_0109_0013 Esi_0109_0012 Esi_0109_0012 IGPS IGPS PGDH PGDH AK AK SATase-2 SATase-2 SATase SATase Esi_0034_0073 Esi_0034_0073 AK1 AK1 Esi_0320_0040 Esi_0320_0040 Esi_0311_0010 Esi_0311_0010 ilvB ilvB ilvH ilvH TIC-3 TIC-3 TIC-2 TIC-2 Esi_0007_0171 Esi_0007_0171 Esi_0069_0026 Esi_0069_0026 OCD OCD RPE-2 RPE-2 IPMS2 IPMS2 Esi_0060_0108 Esi_0060_0108 Esi_0060_0102 Esi_0060_0102 PYK-2 PYK-2 Esi_0005_0248 Esi_0005_0248 TS TS Esi_0401_0019 Esi_0401_0019 HISF HISF Esi_0038_0153 Esi_0038_0153 Esi_0038_0129 Esi_0038_0129 OTC OTC Esi_0036_0051 Esi_0036_0051 Esi_0036_0001 Esi_0036_0001 SHMT2-2 SHMT2-2 HSK HSK Esi_0031_0082 Esi_0031_0082 CBS CBS Esi_0292_0040 Esi_0292_0040 Esi_0281_0044 Esi_0281_0044 Esi_0281_0043 Esi_0281_0043 TAL2 TAL2 CGL CGL Esi_0264_0007 Esi_0264_0007 BCAT4 BCAT4 ATP-PRT ATP-PRT P5CR-3 P5CR-3 P5CR-2 P5CR-2 Esi_0349_0004 Esi_0349_0004 Esi_0349_0012 Esi_0349_0012 Esi_0378_0002 Esi_0378_0002 Esi_0391_0022 Esi_0391_0022 TPI-2 TPI-2 FBA1-3 FBA1-3 Esi_0042_0138 Esi_0042_0138 Esi_0420_0016 Esi_0420_0016 Esi_0437_0013 Esi_0437_0013 Esi_0437_0015 Esi_0437_0015 IMDH IMDH HDH HDH Esi_0476_0015 Esi_0476_0015 IGPS-2 IGPS-2 Esi_0048_0101 Esi_0048_0101 Esi_0050_0003 Esi_0050_0003 HIS4 HIS4 Esi_0504_0005 Esi_0504_0005 CYS CYS P5CS P5CS P5CR P5CR Esi_0068_0067 Esi_0068_0067 Esi_0068_0069 Esi_0068_0069 ARI ARI P5CR-4 P5CR-4 Esi_0079_0076 Esi_0079_0076 CYS-2 CYS-2 Esi_0008_0180 Esi_0008_0180 OsNAAT1-2 OsNAAT1-2 Esi_0850_0001 Esi_0850_0001 Esi_0086_0074 Esi_0086_0074 Esi_0088_0007 Esi_0088_0007 Esi_0088_0011 Esi_0088_0011 SATase-3 SATase-3 Esi_0098_0077 Esi_0098_0077 IGPS-3 IGPS-3 Esi_0000_0454 Esi_0000_0454 RPE RPE CM-PDT-PDH CM-PDT-PDH signal signal Esi_0100_0065 Esi_0100_0065 Esi_0011_0179 Esi_0011_0179 PYC PYC SATase-4 SATase-4 Esi_0112_0047 Esi_0112_0047 ASS ASS DHDPR DHDPR Esi_0121_0007 Esi_0121_0007 Esi_0121_0078 Esi_0121_0078 Esi_0126_0079 Esi_0126_0079 RPI RPI Esi_0129_0047 Esi_0129_0047 Esi_0013_0196 Esi_0013_0196 Esi_0003_0266 Esi_0003_0266 Esi_0003_0136 Esi_0003_0136 AAT AAT Esi_0298_0027 Esi_0298_0027 Esi_0286_0022 Esi_0286_0022 Esi_0279_0004 Esi_0279_0004 Esi_0279_0001 Esi_0279_0001 Esi_0278_0043 Esi_0278_0043 Esi_0278_0034 Esi_0278_0034 DAD-3 DAD-3 DAD-2 DAD-2 DAD DAD Esi_0027_0091 Esi_0027_0091 Esi_0252_0029 Esi_0252_0029 Esi_0252_0005 Esi_0252_0005 GAP-3 GAP-3 TPI TPI Esi_0216_0030 Esi_0216_0030 Esi_0215_0007 Esi_0215_0007 Esi_0215_0004 Esi_0215_0004 Esi_0214_0047 Esi_0214_0047 Esi_0214_0022 Esi_0214_0022 Esi_0214_0021 Esi_0214_0021 ACO ACO Esi_0002_0203 Esi_0002_0203 Esi_0002_0158 Esi_0002_0158 CM CM FBA1-2 FBA1-2 Esi_0137_0084 Esi_0137_0084 PGK PGK THA1 THA1 SHMT2 SHMT2 Esi_0148_0046 Esi_0148_0046 Esi_0151_0005 Esi_0151_0005 ARGB ARGB HSDH-2 HSDH-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Esi_0061_0003tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. (294 aa)
SHMT2-3Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (491 aa)
Esi_0090_0074Glyceraldehyde-3-phosphate dehydrogenase. (346 aa)
IPMS32-Isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (606 aa)
Esi_0009_00965-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. (806 aa)
TIC-5TIC 20 related, plastid import. (437 aa)
SKShikimate Kinase. (224 aa)
DHQ-SDHBifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase. (696 aa)
ASLArgininosuccinate lyase. (476 aa)
BCAT3-2C-terminal branched chain amino acid aminotransferase BACT3. (116 aa)
BCAT3Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (430 aa)
Esi_0081_0025D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (342 aa)
BCAT2Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (405 aa)
THA2Threonine aldolase. (471 aa)
BCAT1Branched chain amino acid aminotransferase. (352 aa)
Esi_0072_0092Glutamine synthetase. (407 aa)
NAG-PRN-acetyl-gamma-glutamyl-phosphate reductase, C-terminal part. (355 aa)
Esi_0070_0078Phosphoglycerate kinase. (414 aa)
Esi_0070_0073Phosphoglycerate kinase. (411 aa)
TIC20Tic20 protein-related. (413 aa)
TIC-4TIC 20 plastid import protein. (413 aa)
Esi_0007_0086Uncharacterized protein. (400 aa)
Esi_0007_0085Uncharacterized protein. (413 aa)
Esi_0002_0003tRNA (Guanine-N(7)-)-methyltransferase. (235 aa)
PSPPhosphoserine phosphatase. (306 aa)
PYKPyruvate kinase; Belongs to the pyruvate kinase family. (499 aa)
HIS8Histidinol-phosphate transaminase. (400 aa)
Esi_0188_0005Glutamine synthetase. (334 aa)
Esi_0188_0004Glutamine synthetase. (363 aa)
Esi_0187_0064Uncharacterized protein. (346 aa)
Esi_0187_0063Uncharacterized protein. (346 aa)
GAP-2Triosephosphate isomerase/glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (587 aa)
FBA1Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (397 aa)
Esi_0183_00452-hydroxyacid dehydrogenase. (510 aa)
HSDHHomoserine dehydrogenase. (493 aa)
IGP-DHImidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (474 aa)
Esi_0179_0062Novel protein. (1353 aa)
Esi_0175_0040Uncharacterized protein. (304 aa)
SAMS1S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (397 aa)
GAPGlyceraldehyde 3-phosphate dehydrogenase alternative name: imm downregulated 12; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (314 aa)
CBL2Cystathionine beta-lyase. (149 aa)
Esi_0164_0038M20_dimer domain-containing protein. (374 aa)
Esi_0163_0013Uncharacterized protein. (183 aa)
Esi_0016_0192rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (310 aa)
PDGHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (965 aa)
Esi_0016_0022AAA domain-containing protein. (709 aa)
AS-BAsparagine synthase (Glutamine-hydrolyzing). (580 aa)
CBL1Cystathionine beta-lyase. (517 aa)
Esi_0143_0070TPR_REGION domain-containing protein. (440 aa)
Esi_0138_0072Uncharacterized protein. (320 aa)
PGDH-2D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (623 aa)
ARGAAmino-acid N-acetyltransferase. (497 aa)
Esi_0130_0062AB hydrolase-1 domain-containing protein. (344 aa)
Esi_0109_0013Ribose-phosphate pyrophosphokinase. (180 aa)
Esi_0109_0012Phosphoribosylpyrophosphate synthetase. (384 aa)
IGPSIndole-3-glycerol-phosphate synthase. (313 aa)
PGDHPhosphoglycerate dehydrogenase, incomplete; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (304 aa)
AKAspartate kinase/homoserine dehydrogenase. (945 aa)
SATase-2Serine O-acetyltransferase. (479 aa)
SATaseSerine O-acetyltransferase. (322 aa)
Esi_0034_0073Serine O-acetyltransferase. (207 aa)
AK1Aspartokinase; Belongs to the aspartokinase family. (469 aa)
Esi_0320_0040Pribosyltran_N domain-containing protein. (406 aa)
Esi_0311_0010Uncharacterized protein. (2135 aa)
ilvBAcetolactate synthase. (735 aa)
ilvHAcetolactate synthase small subunit. (194 aa)
TIC-3TIC 20 related, plastid import. (413 aa)
TIC-2TIC 20 related, plastid import. (413 aa)
Esi_0007_0171Phosphoglycerate kinase. (427 aa)
Esi_0069_00263-isopropylmalate dehydratase. (255 aa)
OCDOrnithine cyclodeaminase. (348 aa)
RPE-2Ribulose-phosphate 3-epimerase. (285 aa)
IPMS22-Isopropylmalate synthase. (515 aa)
Esi_0060_0108Tryptophan synthase (Alpha / beta chains). (681 aa)
Esi_0060_0102rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (433 aa)
PYK-2Pyruvate kinase; Belongs to the pyruvate kinase family. (623 aa)
Esi_0005_0248tRNA (Guanine-N(7)-)-methyltransferase trmB. (375 aa)
TSThreonine synthase. (492 aa)
Esi_0401_0019Transaldolase B. (422 aa)
HISFImidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (584 aa)
Esi_0038_0153M20_dimer domain-containing protein. (446 aa)
Esi_0038_0129Carboxylase. (1235 aa)
OTCOrnithine transcarbamoylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (320 aa)
Esi_0036_0051Tryptophan synthase (Alpha / beta chains). (741 aa)
Esi_0036_0001Similar to Calcium-independent phospholipase A2-gamma, C terminal part. (370 aa)
SHMT2-2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (538 aa)
HSKHomoserine kinase. (467 aa)
Esi_0031_0082Chorismate Synthase. (437 aa)
CBSCystathionine beta-synthase. (572 aa)
Esi_0292_0040Uncharacterized protein. (194 aa)
Esi_0281_0044Bifunctional Indole-3-Glycerol Phosphate Synthase/Phosphoribosylanthranilate Isomerase (N-terminal). (210 aa)
Esi_0281_0043Bifunctional Indole-3-Glycerol Phosphate Synthase/Phosphoribosylanthranilate Isomerase (C-terminal). (411 aa)
TAL2Threonine dehydratase. (595 aa)
CGLCystathionine gamma-lyase. (400 aa)
Esi_0264_0007SUI1 domain-containing protein. (712 aa)
BCAT4Branched chain amino acid aminotransferase. (614 aa)
ATP-PRTATP phosphoribosyltransferase. (304 aa)
P5CR-3Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (335 aa)
P5CR-2Delta-1-pyrroline-5-carboxylate reductase, partial. (59 aa)
Esi_0349_0004Enolase. (455 aa)
Esi_0349_0012Pyruvate kinase; Belongs to the pyruvate kinase family. (504 aa)
Esi_0378_0002Glyceraldehyde-3-phosphate dehydrogenase. (324 aa)
Esi_0391_0022Diaminopimelate epimerase. (285 aa)
TPI-2Triosephosphate isomerase. (257 aa)
FBA1-3Fructose-1,6-bisphosphate aldolase. (380 aa)
Esi_0042_0138Helicase C-terminal domain-containing protein. (238 aa)
Esi_0420_0016Pribosyltran domain-containing protein; Belongs to the ribose-phosphate pyrophosphokinase family. (340 aa)
Esi_0437_0013Pyrophosphate-dependent phosphofructose kinase. (549 aa)
Esi_0437_00156-phosphofructokinase. (109 aa)
IMDH3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (427 aa)
HDHHistidinol dehydrogenase; Belongs to the histidinol dehydrogenase family. (426 aa)
Esi_0476_0015Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate; Belongs to the ArgJ family. (473 aa)
IGPS-2annotation not available (387 aa)
Esi_0048_0101Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
Esi_0050_0003Putative periplasmic protease. (898 aa)
HIS41-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family. (292 aa)
Esi_0504_0005Uncharacterized protein. (164 aa)
CYSCysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (345 aa)
P5CSDelta-1-pyrroline-5-carboxylate synthase. (625 aa)
P5CRDelta-1-pyrroline-5-carboxylate reductase, partial. (107 aa)
Esi_0068_0067Putative homoaconitate hydratase, c-terminal part. (283 aa)
Esi_0068_0069Putative homoaconitate hydratase, N-terminal part. (278 aa)
ARIArginase; Belongs to the arginase family. (383 aa)
P5CR-4Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (279 aa)
Esi_0079_0076Uncharacterized protein. (893 aa)
CYS-2Cysteine synthase. (422 aa)
Esi_0008_0180Cysteine synthase. (354 aa)
OsNAAT1-2Nicotinanamine aminotransferase A. (490 aa)
Esi_0850_0001Uncharacterized protein. (573 aa)
Esi_0086_0074Similar to 2-Epi-5-Epi-Valiolone Synthase (Sedoheptulose 7-Phosphate Cyclase). (434 aa)
Esi_0088_0007Uncharacterized protein. (737 aa)
Esi_0088_0011UBA/TS-N domain containing protein. (825 aa)
SATase-3Serine O-acetyltransferase. (451 aa)
Esi_0098_0077Glutamine amidotransferase type-2 domain-containing protein. (1083 aa)
IGPS-3Indole-3-glycerol-phosphate synthase. (903 aa)
Esi_0000_0454Uncharacterized protein. (522 aa)
RPERibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (276 aa)
CM-PDT-PDHTrifunctional Chorismate Mutase/Prephenate Dehydratase/Prephenate Dehydrogenase. (729 aa)
signalSignal peptide peptidase. (915 aa)
Esi_0100_0065Uncharacterized protein. (480 aa)
Esi_0011_0179PALP domain-containing protein. (490 aa)
PYCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1152 aa)
SATase-4Serine O-acetyltransferase, incomplete. (333 aa)
Esi_0112_0047AAA domain-containing protein; Belongs to the AAA ATPase family. (498 aa)
ASSArgininosuccinate synthetase. (432 aa)
DHDPRDihydrodipicolinate reductase. (333 aa)
Esi_0121_0007Uncharacterized protein. (447 aa)
Esi_0121_0078PRA-CH domain-containing protein. (461 aa)
Esi_0126_0079Uncharacterized protein. (3616 aa)
RPIRibose-5-phosphate isomerase. (234 aa)
Esi_0129_0047Uncharacterized protein. (380 aa)
Esi_0013_01963-Dehydroquinate Synthase. (444 aa)
Esi_0003_0266Anthranilate Phosphoribosyltransferase. (372 aa)
Esi_0003_0136Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (693 aa)
AATAspartate aminotransferase. (401 aa)
Esi_0298_0027Alanine transaminase. (510 aa)
Esi_0286_0022Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (1147 aa)
Esi_0279_0004DNA repair protein. (644 aa)
Esi_0279_0001Uncharacterized protein. (126 aa)
Esi_0278_0043PARP catalytic domain-containing protein. (571 aa)
Esi_0278_0034PARP catalytic domain-containing protein. (939 aa)
DAD-3Dihydroxy-acid dehydratase, N-termnial part. (312 aa)
DAD-2Dihydroxy-acid dehydratase. (64 aa)
DADDihydroxy-acid dehydratase, C-termnial part. (213 aa)
Esi_0027_0091Aminotran_1_2 domain-containing protein. (386 aa)
Esi_0252_0029Putative fusion of putative sugar/xylulosekinase and ribulose-phosphate epimerase. (475 aa)
Esi_0252_0005Pribosyltran_N domain-containing protein. (461 aa)
GAP-3Glyceraldehyde-3-phosphate dehydrogenase. (385 aa)
TPITriosephosphate isomerase. (255 aa)
Esi_0216_0030Pyrophosphate-dependent phosphofructose kinase. (488 aa)
Esi_0215_0007M20_dimer domain-containing protein. (489 aa)
Esi_0215_0004Signal peptide peptidase. (625 aa)
Esi_0214_0047Uncharacterized protein. (386 aa)
Esi_0214_0022Uncharacterized protein. (399 aa)
Esi_0214_0021Uncharacterized protein. (339 aa)
ACOAconitate hydratase. (788 aa)
Esi_0002_0203Uncharacterized protein. (370 aa)
Esi_0002_0158Aspartate-semialdehyde dehydrogenase. (348 aa)
CMChorismate Mutase. (396 aa)
FBA1-2Fructose-1,6-bisphosphate aldolase. (413 aa)
Esi_0137_00843-phosphoshikimate 1-carboxyvinyltransferase; Belongs to the EPSP synthase family. (515 aa)
PGKPhosphoglycerate kinase. (485 aa)
THA1Threonine aldolase. (1025 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (471 aa)
Esi_0148_0046Uncharacterized protein. (396 aa)
Esi_0151_0005Phosphoglycerate kinase. (444 aa)
ARGBAcetylglutamate kinase. (359 aa)
HSDH-2Homoserine dehydrogenase. (434 aa)
Your Current Organism:
Ectocarpus siliculosus
NCBI taxonomy Id: 2880
Other names: E. siliculosus
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