83 items (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AP2M1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (435 aa)
	apoe	Uncharacterized protein. (252 aa)
	LOC100557849	Uncharacterized protein. (407 aa)
	LOC103282660	Adaptin_N domain-containing protein. (164 aa)
	ANGPTL3	Angiopoietin like 3. (422 aa)
	H9GRS7_ANOCA	Ubiquitin-like domain-containing protein. (33 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (69 aa)
	LOC100553583	Uncharacterized protein. (1754 aa)
	LOC100564642	Uncharacterized protein. (1493 aa)
	APOF	Apolipoprotein F. (257 aa)
	LOC100565869	Uncharacterized protein. (329 aa)
	G1KZB6_ANOCA	Uncharacterized protein. (1398 aa)
	LOC100561183	UPAR/Ly6 domain-containing protein. (126 aa)
	LOC100559048	Uncharacterized protein. (1473 aa)
	R4GC60_ANOCA	SSD domain-containing protein. (526 aa)
	LOC100560787	UPAR/Ly6 domain-containing protein. (125 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (417 aa)
	LCAT	Lecithin-cholesterol acyltransferase. (442 aa)
	LSR	Lipolysis stimulated lipoprotein receptor. (578 aa)
	Prkaca	Uncharacterized protein. (172 aa)
	ILDR2	Immunoglobulin like domain containing receptor 2. (640 aa)
	LOC100565626	Vitellogenin domain-containing protein. (887 aa)
	CETP	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (500 aa)
	ZDHHC8	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (804 aa)
	LOC100564258	SSD domain-containing protein. (896 aa)
	PTCHD1	Patched domain containing 1. (905 aa)
	ZDHHC5	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (724 aa)
	Zdhhc19	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (161 aa)
	LOC100552825	Uncharacterized protein. (410 aa)
	LMF1	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (563 aa)
	LOC103282702	P/Homo B domain-containing protein. (214 aa)
	H9GAF3_ANOCA	Uncharacterized protein. (1812 aa)
	H9GAE5_ANOCA	Uncharacterized protein. (662 aa)
	PCSK5	Proprotein convertase subtilisin/kexin type 5. (1698 aa)
	PLEKHD1	Pleckstrin homology and coiled-coil domain containing D1. (501 aa)
	Cubn	Uncharacterized protein. (2240 aa)
	FURIN	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (885 aa)
	LOC100558432	Uncharacterized protein. (1257 aa)
	MYLIP	Myosin regulatory light chain interacting protein. (445 aa)
	LOC100558851	Uncharacterized protein. (1479 aa)
	ubc	Uncharacterized protein. (381 aa)
	H9GQ07_ANOCA	Uncharacterized protein. (405 aa)
	PLG	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (801 aa)
	rps27a	Ubiquitin-like domain-containing protein. (156 aa)
	CLHC1	Clathrin heavy chain linker domain-containing protein 1. (592 aa)
	pcsk6	PLAC domain-containing protein. (146 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (408 aa)
	LOC100557651	Uncharacterized protein. (407 aa)
	H9G675_ANOCA	Uncharacterized protein. (403 aa)
	LOC100560210	Uncharacterized protein. (412 aa)
	SAR1B	Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	HDLBP	High density lipoprotein binding protein. (1267 aa)
	LOC100564843	Uncharacterized protein. (1522 aa)
	NPC2	NPC intracellular cholesterol transporter 2. (148 aa)
	NCEH1	Neutral cholesterol ester hydrolase 1. (361 aa)
	AP2A2	Alpha_adaptinC2 domain-containing protein. (852 aa)
	pdia2	Uncharacterized protein. (552 aa)
	LOC100557873	Uncharacterized protein. (1439 aa)
	LOC100558263	Uncharacterized protein. (1492 aa)
	LIPC	Lipase C, hepatic type. (513 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (539 aa)
	PLTP	Phospholipid transfer protein. (489 aa)
	CDCP2	CUB domain containing protein 2. (351 aa)
	LPL	Lipoprotein lipase. (466 aa)
	Ldlrap1	PID domain-containing protein. (64 aa)
	H9GK63_ANOCA	Uncharacterized protein. (304 aa)
	ap2a1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (967 aa)
	PTCHD4	Patched domain containing 4. (863 aa)
	LMF2	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (685 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (436 aa)
	LOC100560410	Uncharacterized protein. (350 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9. (690 aa)
	AMN	Amnion associated transmembrane protein. (484 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (572 aa)
	sar1a	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	SMPDL3A	Acid sphingomyelinase-like phosphodiesterase. (455 aa)
	APOA4	Apolipoprotein A4. (369 aa)
	MTTP	Microsomal triglyceride transfer protein. (892 aa)
	LOC103279522	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (223 aa)
	AP2S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	APOB	Apolipoprotein B. (4561 aa)
	P4HB	Protein disulfide-isomerase. (538 aa)
	LOC100566071	Uncharacterized protein. (410 aa)

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMN	CDCP2	ENSACAP00000000200	ENSACAP00000013894	Amnion associated transmembrane protein.	CUB domain containing protein 2.	0.852
AMN	Cubn	ENSACAP00000000200	ENSACAP00000004939	Amnion associated transmembrane protein.	Uncharacterized protein.	0.936
AMN	G1KZB6_ANOCA	ENSACAP00000000200	ENSACAP00000021577	Amnion associated transmembrane protein.	Uncharacterized protein.	0.936
ANGPTL3	APOB	ENSACAP00000018729	ENSACAP00000010611	Angiopoietin like 3.	Apolipoprotein B.	0.591
ANGPTL3	LMF1	ENSACAP00000018729	ENSACAP00000005999	Angiopoietin like 3.	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	0.519
ANGPTL3	NCEH1	ENSACAP00000018729	ENSACAP00000016136	Angiopoietin like 3.	Neutral cholesterol ester hydrolase 1.	0.400
ANGPTL3	PCSK9	ENSACAP00000018729	ENSACAP00000000160	Angiopoietin like 3.	Proprotein convertase subtilisin/kexin type 9.	0.435
ANGPTL3	PLG	ENSACAP00000018729	ENSACAP00000003302	Angiopoietin like 3.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.402
AP2A2	AP2M1	ENSACAP00000015443	ENSACAP00000010344	Alpha_adaptinC2 domain-containing protein.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.995
AP2A2	AP2S1	ENSACAP00000015443	ENSACAP00000011452	Alpha_adaptinC2 domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.995
AP2A2	H9GK63_ANOCA	ENSACAP00000015443	ENSACAP00000013468	Alpha_adaptinC2 domain-containing protein.	Uncharacterized protein.	0.425
AP2A2	UBA52	ENSACAP00000015443	ENSACAP00000019197	Alpha_adaptinC2 domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.423
AP2A2	ap2a1	ENSACAP00000015443	ENSACAP00000013323	Alpha_adaptinC2 domain-containing protein.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.935
AP2A2	rps27a	ENSACAP00000015443	ENSACAP00000003208	Alpha_adaptinC2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.464
AP2A2	ubc	ENSACAP00000015443	ENSACAP00000017814	Alpha_adaptinC2 domain-containing protein.	Uncharacterized protein.	0.425
AP2M1	AP2A2	ENSACAP00000010344	ENSACAP00000015443	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Alpha_adaptinC2 domain-containing protein.	0.995
AP2M1	AP2S1	ENSACAP00000010344	ENSACAP00000011452	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
AP2M1	APOB	ENSACAP00000010344	ENSACAP00000010611	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Apolipoprotein B.	0.565
AP2M1	CLHC1	ENSACAP00000010344	ENSACAP00000003184	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Clathrin heavy chain linker domain-containing protein 1.	0.763
AP2M1	H9GK63_ANOCA	ENSACAP00000010344	ENSACAP00000013468	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Uncharacterized protein.	0.592