STRINGSTRING
DNA2 DNA2 EXO1 EXO1 RFC3 RFC3 ATAD5 ATAD5 WRN WRN RFC1 RFC1 RFC5 RFC5 RFC4 RFC4 PCNA PCNA LIG1 LIG1 FEN1 FEN1 RFC2 RFC2 ENSTSYP00000034634 ENSTSYP00000034634
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DNA2DNA replication ATP-dependent helicase/nuclease DNA2. (1061 aa)
EXO1Exonuclease 1 isoform X1. (846 aa)
RFC3Replication factor C subunit 3 isoform X1. (270 aa)
ATAD5ATPase family AAA domain-containing protein 5-like. (1204 aa)
WRNLOW QUALITY PROTEIN: Werner syndrome ATP-dependent helicase. (1403 aa)
RFC1Replication factor C subunit 1. (1147 aa)
RFC5Replication factor C subunit 5 isoform X1. (339 aa)
RFC4Replication factor C subunit 4. (363 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
LIG1DNA ligase. (936 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
RFC2Replication factor C subunit 2 isoform X1. (352 aa)
ENSTSYP00000034634annotation not available (328 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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