STRINGSTRING
espA espA fliC fliC espB espB espD espD eae eae tir tir Z5444 Z5444
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
espASecreted protein EspA; Residues 1 to 192 of 192 are 100.00 pct identical to residues 1 to 192 of 192 from GenPept 118 : gi|3414890|gb|AAC31501.1| (AF071034) L0022 [Escherichia coli]. (192 aa)
fliCFlagellar biosynthesis; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (585 aa)
espBSecreted protein EspB; Residues 1 to 312 of 312 are 99.67 pct identical to residues 1 to 312 of 312 from GenPept 118 : gi|3115186|emb|CAA73508.1| (Y13068) EspB protein [Escherichia coli]. (312 aa)
espDSecreted protein EspD; Residues 1 to 374 of 374 are 100.00 pct identical to residues 1 to 374 of 374 from GenPept 118 : gi|3414889|gb|AAC31500.1| (AF071034) L0021 [Escherichia coli]. (374 aa)
eaeIntimin adherence protein; Necessary for the production of attaching and effacing lesions on tissue culture cells; Belongs to the intimin/invasin family. (934 aa)
tirPutative translocated intimin receptor protein; Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion. In strain EDL933, acts via the effector protein EspF(U), in a phosphotyrosine- and NCK- independent [...] (558 aa)
Z5444Putative glycoporin; Residues 1 to 464 of 464 are 78.01 pct identical to residues 1 to 464 of 464 from GenPept 118 : gi|1773072|gb|AAB71432.1| (U82290) putative glycoporin [Escherichia coli]. (464 aa)
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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