STRINGSTRING
CBH20755.1 CBH20755.1 folD folD lysA lysA mtnK mtnK CBH20516.1 CBH20516.1 asnB asnB thrB thrB thrC thrC metAA metAA pfs pfs CBH20275.1 CBH20275.1 CBH20274.1 CBH20274.1 CBH20211.1 CBH20211.1 asd asd dapF dapF dapA dapA dapB dapB dapH dapH CBH21533.1 CBH21533.1 CBH21293.1 CBH21293.1 CBH21290.1 CBH21290.1 CBH21202.1 CBH21202.1 CBH21149.1 CBH21149.1 CBH21026.1 CBH21026.1 mtnA mtnA mtrK mtrK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBH20755.1Putative amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (380 aa)
folDBifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa)
mtnK5-methylribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (406 aa)
CBH20516.1Putative translation initiation factor EIF-2B subunit 1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the eIF-2B alpha/beta/delta subunits family. (350 aa)
asnBAsparagine synthase (Glutamine-hydrolyzing). (605 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (298 aa)
thrCThrC; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (353 aa)
metAAHomoserine O-succinyltransferase (Homoserine O-transsuccinylase) (HTS) (modular protein); Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (589 aa)
pfs5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (230 aa)
CBH20275.1Homologs of previously reported genes of unknown function. (211 aa)
CBH20274.1Putative 5-methyltetrahydrofolate--homocysteine methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (770 aa)
CBH20211.1Homologs of previously reported genes of unknown function. (595 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (327 aa)
dapFDiaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (281 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa)
dapBDihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (253 aa)
dapHTetrahydrodipicolinate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (238 aa)
CBH21533.1Aspartokinase; Belongs to the aspartokinase family. (442 aa)
CBH21293.1Ferredoxin; Function of strongly homologous gene; transporter. (643 aa)
CBH21290.15-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (261 aa)
CBH21202.1Homologs of previously reported genes of unknown function. (215 aa)
CBH21149.1Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (222 aa)
CBH21026.1Homoserine dehydrogenase. (403 aa)
mtnAPutative Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (354 aa)
mtrK5-methylribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (401 aa)
Your Current Organism:
Acetoanaerobium sticklandii
NCBI taxonomy Id: 1511
Other names: A. sticklandii, ATCC 12662, BCRC 14485, CCRC 14485, CCRC:14485, CCUG 9281, Clostridium sticklandii, DSM 519, NCIMB 10654, strain StadtmanHF
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