STRINGSTRING
thiE thiE AJY48526.1 AJY48526.1 AJY48559.1 AJY48559.1 AJY48780.1 AJY48780.1 thiG thiG AJY48803.1 AJY48803.1 dxs dxs AJY48857.1 AJY48857.1 AJY50630.1 AJY50630.1 thiL thiL AJY51611.1 AJY51611.1 thiC thiC AJY51753.1 AJY51753.1 thiM thiM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (207 aa)
AJY48526.1PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: thiD; phosphomethylpyrimidine kinase. (269 aa)
AJY48559.1KEGG: hypothetical protein. (230 aa)
AJY48780.1TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: thiD; phosphomethylpyrimidine kinase. (276 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (269 aa)
AJY48803.1TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamine S protein; KEGG: thiS; thiamine biosynthesis protein ThiS. (68 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (641 aa)
AJY48857.1Hypothetical protein; KEGG: ssuA; putative periplasmic-binding protein. (362 aa)
AJY50630.1Hypothetical protein; KEGG: ABC transporter periplasmic protein. (381 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (333 aa)
AJY51611.1TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; KEGG: cof; hypothetical protein. (265 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (629 aa)
AJY51753.1KEGG: thiC; thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC. (272 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (269 aa)
Your Current Organism:
Halomonas sp. KO116
NCBI taxonomy Id: 1504981
Other names: H. sp. KO116
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