30 items (Pediculus humanus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	E0VF66_PEDHC	DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide, putative. (132 aa)
	E0VCI8_PEDHC	DNA excision repair protein haywire, putative. (794 aa)
	E0VCF0_PEDHC	TFIIH basal transcription factor complex subunit, putative. (560 aa)
	E0VBV6_PEDHC	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (124 aa)
	E0VAF8_PEDHC	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
	E0V9D3_PEDHC	Cyclin H, putative (Fragment); Belongs to the cyclin family. (155 aa)
	E0V959_PEDHC	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	E0V939_PEDHC	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (121 aa)
	E0V937_PEDHC	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (130 aa)
	E0V8Y6_PEDHC	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1114 aa)
	E0W4E7_PEDHC	Glutamic acid-rich protein precursor, putative. (817 aa)
	E0W239_PEDHC	TFIIH basal transcription factor complex helicase subunit, putative. (747 aa)
	E0W1Z4_PEDHC	Coiled-coil domain-containing protein, putative. (633 aa)
	E0VZG8_PEDHC	Trf2 protein, putative. (298 aa)
	E0VYT4_PEDHC	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (467 aa)
	E0VYJ4_PEDHC	DNA-directed RNA polymerase I 40 kDa polypeptide, putative. (347 aa)
	E0VXR9_PEDHC	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa)
	E0VXR4_PEDHC	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (115 aa)
	E0VV37_PEDHC	SprT-like domain-containing protein. (518 aa)
	E0VUA1_PEDHC	Transcription initiation factor ia, putative. (555 aa)
	E0VSA8_PEDHC	DNA-directed RNA polymerase II 23 kDa polypeptide, putative. (210 aa)
	E0VRJ7_PEDHC	Mitogen-activated protein kinase ERK-A, putative; Belongs to the protein kinase superfamily. (340 aa)
	E0VQA4_PEDHC	Trf2 protein, putative. (289 aa)
	E0VNT9_PEDHC	Trf2 protein, putative. (231 aa)
	E0VLT0_PEDHC	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1659 aa)
	E0VLM4_PEDHC	DNA-directed RNA polymerases I, II, and III 7.0 kDa polypeptide, putative. (57 aa)
	E0VKS5_PEDHC	TFIIH basal transcription factor complex TTD-A subunit, putative. (71 aa)
	E0VIS9_PEDHC	DNA-directed RNA polymerase I-associated factor 53 kDa subunit, putative. (311 aa)
	E0VGE5_PEDHC	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	E0VFY0_PEDHC	General transcription factor IIH subunit. (401 aa)

Your Current Organism:

Pediculus humanus

NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E0V8Y6_PEDHC	E0V937_PEDHC	E0V8Y6	E0V937	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.542
E0V8Y6_PEDHC	E0V939_PEDHC	E0V8Y6	E0V939	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.542
E0V8Y6_PEDHC	E0V959_PEDHC	E0V8Y6	E0V959	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.542
E0V8Y6_PEDHC	E0V9D3_PEDHC	E0V8Y6	E0V9D3	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Cyclin H, putative (Fragment); Belongs to the cyclin family.	0.767
E0V8Y6_PEDHC	E0VAF8_PEDHC	E0V8Y6	E0VAF8	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.859
E0V8Y6_PEDHC	E0VBV6_PEDHC	E0V8Y6	E0VBV6	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.998
E0V8Y6_PEDHC	E0VCF0_PEDHC	E0V8Y6	E0VCF0	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	TFIIH basal transcription factor complex subunit, putative.	0.859
E0V8Y6_PEDHC	E0VCI8_PEDHC	E0V8Y6	E0VCI8	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA excision repair protein haywire, putative.	0.889
E0V8Y6_PEDHC	E0VF66_PEDHC	E0V8Y6	E0VF66	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide, putative.	0.999
E0V8Y6_PEDHC	E0VFY0_PEDHC	E0V8Y6	E0VFY0	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	General transcription factor IIH subunit.	0.872
E0V8Y6_PEDHC	E0VGE5_PEDHC	E0V8Y6	E0VGE5	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.995
E0V8Y6_PEDHC	E0VIS9_PEDHC	E0V8Y6	E0VIS9	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase I-associated factor 53 kDa subunit, putative.	0.999
E0V8Y6_PEDHC	E0VKS5_PEDHC	E0V8Y6	E0VKS5	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	TFIIH basal transcription factor complex TTD-A subunit, putative.	0.673
E0V8Y6_PEDHC	E0VLM4_PEDHC	E0V8Y6	E0VLM4	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerases I, II, and III 7.0 kDa polypeptide, putative.	0.997
E0V8Y6_PEDHC	E0VLT0_PEDHC	E0V8Y6	E0VLT0	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
E0V8Y6_PEDHC	E0VNT9_PEDHC	E0V8Y6	E0VNT9	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Trf2 protein, putative.	0.767
E0V8Y6_PEDHC	E0VQA4_PEDHC	E0V8Y6	E0VQA4	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Trf2 protein, putative.	0.695
E0V8Y6_PEDHC	E0VRJ7_PEDHC	E0V8Y6	E0VRJ7	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Mitogen-activated protein kinase ERK-A, putative; Belongs to the protein kinase superfamily.	0.688
E0V8Y6_PEDHC	E0VSA8_PEDHC	E0V8Y6	E0VSA8	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase II 23 kDa polypeptide, putative.	0.999
E0V8Y6_PEDHC	E0VUA1_PEDHC	E0V8Y6	E0VUA1	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Transcription initiation factor ia, putative.	0.997